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Rüdiger Köhling

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Matthew C Walker; Rüdiger Köhling
The problems facing epilepsy therapy.
Lorenz Müller; Katrin Porath; Tursonjan Tokay; Rüdiger Köhling; Timo Kirschstein
Enhanced NMDA receptor-dependent LTP in the epileptic CA1 area via upregulation of NR2B.
Massimo Avoli; Marco de Curtis; Rüdiger Köhling
Does interictal synchronization influence ictogenesis?

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All Publications

2013: Matthew C Walker; Rüdiger Köhling
The problems facing epilepsy therapy.
Neuropharmacology 2013;69():1-2.
2013: Lorenz Müller; Katrin Porath; Tursonjan Tokay; Rüdiger Köhling; Timo Kirschstein
Enhanced NMDA receptor-dependent LTP in the epileptic CA1 area via upregulation of NR2B.
Neurobiology of disease 2013;54():183-93.
2013: Massimo Avoli; Marco de Curtis; Rüdiger Köhling
Does interictal synchronization influence ictogenesis?
Neuropharmacology 2013;69():37-44.
2012: Yosef Avchalumov; Timo Kirschstein; Jan Lukas; Jiankai Luo; Arndt Rolfs; Andreas Wree; Rüdiger Köhling
Increased excitability and compromised long-term potentiation in the neocortex of NPC1(-/-) mice.
Brain research 2012;1444():20-6.
2012: Judith Rohde; Tursonjan Tokay; Wiebke Wilkars; Roland A Bender; Timo Kirschstein; Lorenz Müller; Katrin Porath; Rüdiger Köhling
Upregulation of presynaptic mGluR2, but not mGluR3 in the epileptic medial perforant path.
Neuropharmacology 2012;62(4):1867-73.
2012: Xiati Guli; Rüdiger Köhling; Marco Rohde; Tursonjan Tokay; Roland A Bender; Timo Kirschstein
ZD7288 enhances long-term depression at early postnatal medial perforant path-granule cell synapses.
Neural plasticity 2012;2012():237913.
2012: Robert Schulz; Hannes Brehme; Timo Kirschstein; Ulrike Mikkat; Katrin Porath; Rüdiger Köhling
Network excitability in a model of chronic temporal lobe epilepsy critically depends on SK channel-mediated AHP currents.
Neurobiology of disease 2012;45(1):337-47.
2011: Xin Yan; Arndt Rolfs; Martin Witt; Andreas Wree; Moritz Frech; Rayk Hübner; Rüdiger Köhling; Jan Lukas; Jiankai Luo
Decreased expression of myelin gene regulatory factor in Niemann-Pick type C 1 mouse.
Metabolic brain disease 2011;26(4):299-306.
2011: Rüdiger Köhling; Kevin Staley
Network mechanisms for fast ripple activity in epileptic tissue.
Epilepsy research 2011;97(3):318-23.
2011: Gleb Barmashenko; Stefan Hefft; Timo Kirschstein; Ad Aertsen; Rüdiger Köhling
Positive shifts of the GABAA receptor reversal potential due to altered chloride homeostasis is widespread after status epilepticus.
Epilepsia 2011;52(9):1570-8.
2011: Rika Bajorat; Timo Kirschstein; Tina Sellmann; Marleen Wilde; Rüdiger Köhling
Seizure frequency in pilocarpine-treated rats is independent of circadian rhythm.
Epilepsia 2011;52(9):e118-22.
2011: Yosef Avchalumov; Timo Kirschstein; Rüdiger Köhling
Altered physiology and pharmacology in the corticostriatal system in a model of temporal lobe epilepsy.
Epilepsia 2011;52(1):151-7.
2010: Wolfgang Löscher; Rüdiger Köhling
Functional, metabolic, and synaptic changes after seizures as potential targets for antiepileptic therapy.
Epilepsy & behavior : E&B 2010;19(2):105-13.
2010: Steve Hildebrandt; Anke Schmidt; Anja Stoll; Oliver Schmitt; Rüdiger Köhling; Andreas Wree; Stefan J-P Haas; Brigitte M Pützer
Targeting of neural stem cells in the hippocampus of adult rats by custom-made Ad vectors.
Brain structure & function 2010;215(2):105-13.
2010: Anju Vasudevan; Matthew S P Ho; Marco Weiergräber; Roswitha Nischt; Toni Schneider; Ailing Lie; Neil Smyth; Rüdiger Köhling
Basement membrane protein nidogen-1 shapes hippocampal synaptic plasticity and excitability.
Hippocampus 2010;20(5):608-20.
2010: Marco Weiergräber; Ulrich Stephani; Rüdiger Köhling
Voltage-gated calcium channels in the etiopathogenesis and treatment of absence epilepsy.
Brain research reviews 2010;62(2):245-71.
2010: Margherita D'Antuono; Rüdiger Köhling; Serena Ricalzone; Jean Gotman; Giuseppe Biagini; Massimo Avoli
Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro.
Epilepsia 2010;51(3):423-31.
2009: Marco Rohde; Tursonjan Tokay; Rüdiger Köhling; Timo Kirschstein
GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses.
Neuroscience letters 2009;467(1):20-5.
2009: Tursonjan Tokay; Marco Rohde; Sabine Krabbe; Mirko Rehberg; Roland A Bender; Rüdiger Köhling; Timo Kirschstein
HCN1 channels constrain DHPG-induced LTD at hippocampal Schaffer collateral-CA1 synapses.
Learning & memory (Cold Spring Harbor, N.Y.) 2009;16(12):769-76.
2009: Timo Kirschstein; Fabian Dammann; Jenny Klostermann; Mirko Rehberg; Tursonjan Tokay; Rudolf Schubert; Rüdiger Köhling
Dopamine induces contraction in the proximal, but relaxation in the distal rat isolated small intestine.
Neuroscience letters 2009;465(1):21-6.
2009: Tursonjan Tokay; Norman Holl; Timo Kirschstein; Volker Zschorlich; Rüdiger Köhling
High-frequency magnetic stimulation induces long-term potentiation in rat hippocampal slices.
Neuroscience letters 2009;461(2):150-4.
2009: Timo Kirschstein; Mirko Rehberg; Rika Bajorat; Tursonjan Tokay; Katrin Porath; Rüdiger Köhling
High K+-induced contraction requires depolarization-induced Ca2+ release from internal stores in rat gut smooth muscle.
Acta pharmacologica Sinica 2009;30(8):1123-31.
2009: Timo Kirschstein; Rüdiger Köhling
What is the source of the EEG?
Clinical EEG and neuroscience : official journal of the EEG and Clinical Neuroscience Society (ENCS) 2009;40(3):146-9.
2008: Ulf Strauss; Fu-Wen Zhou; Jeannette Henning; Arne Battefeld; Andreas Wree; Rüdiger Köhling; Stefan Jean-Pierre Haas; Reiner Benecke; Arndt Rolfs; Ulrike Gimsa
Increasing extracellular potassium results in subthalamic neuron activity resembling that seen in a 6-hydroxydopamine lesion.
Journal of neurophysiology 2008;99(6):2902-15.
2006: Rüdiger Köhling; Massimo Avoli
Methodological approaches to exploring epileptic disorders in the human brain in vitro.
Journal of neuroscience methods 2006;155(1):1-19.
2006: Anke Wallraff; Rüdiger Köhling; Uwe Heinemann; Martin Theis; Klaus Willecke; Christian Steinhäuser
The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(20):5438-47.
2006: Johannes Wölfer; Carsten Bantel; Rüdiger Köhling; Erwin-Josef Speckmann; Hansdetlef Wassmann; Christoph Greiner
Electrophysiology in ischemic neocortical brain slices: species differences vs. influences of anaesthesia and preparation.
The European journal of neuroscience 2006;23(7):1795-800.
2006: Rüdiger Köhling; Volker Senner; Werner Paulus; Erwin-Josef Speckmann
Epileptiform activity preferentially arises outside tumor invasion zone in glioma xenotransplants.
Neurobiology of disease 2006;22(1):64-75.
2006: Rüdiger Köhling; Roswitha Nischt; Anju Vasudevan; Matthew Ho; Marco Weiergräber; Toni Schneider; Neil Smyth
Nidogen and nidogen-associated basement membrane proteins and neuronal plasticity.
Neuro-degenerative diseases 2006;3(1-2):56-61.
2005: Rüdiger Köhling; Raffaella Melani; Uwe Koch; Erwin-Josef Speckmann; Milena Koudelka-Hep; Pierre Thiébaud; Maurizio Balestrino
Detection of electrophysiological indicators of neurotoxicity in human and rat brain slices by a three-dimensional microelectrode array.
Alternatives to laboratory animals : ATLA 2005;33(6):579-89.
2005: Massimo Avoli; Jacques Louvel; René Pumain; Rüdiger Köhling
Cellular and molecular mechanisms of epilepsy in the human brain.
Progress in neurobiology 2005;77(3):166-200.
2005: Uwe-Robert Koch; Ulrich Musshoff; Heinz Wolfgang Pannek; alois ebner; Peter Wolf; Erwin-Josef Speckmann; Rüdiger Köhling
Intrinsic excitability, synaptic potentials, and short-term plasticity in human epileptic neocortex.
Journal of neuroscience research 2005;80(5):715-26.
2005: Christoph Redecker; Georg Hagemann; Rüdiger Köhling; Heidrun Straub; Otto W Witte; Erwin-Josef Speckmann
Optical imaging of epileptiform activity in experimentally induced cortical malformations.
Experimental neurology 2005;192(2):288-98.
2005: Juergen Fell; Rüdiger Köhling; Thomas Grunwald; Peter Klaver; Thomas Dietl; Carlo Schaller; Albert Becker; Christian E Elger; Guillén Fernández
Phase-locking characteristics of limbic P3 responses in hippocampal sclerosis.
NeuroImage 2005;24(4):980-9.
2005: Frank Pillekamp; Michael Reppel; Vera Dinkelacker; Yaqi Duan; Nathalie Jazmati; Wilhelm Bloch; Konrad Brockmeier; Jürgen Hescheler; Bernd K Fleischmann; Rüdiger Köhling
Establishment and characterization of a mouse embryonic heart slice preparation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2005;16(1-3):127-32.
2004: Christiane Rüschenschmidt; Heidrun Straub; Rüdiger Köhling; Elke Siep; Ali Gorji; Erwin-Josef Speckmann
Reduction of human neocortical and guinea pig CA1-neuron A-type currents by organic calcium channel blockers.
Neuroscience letters 2004;368(1):57-62.
2004: Margherita D'Antuono; Jacques Louvel; Rüdiger Köhling; Donatella Mattia; A Bernasconi; André Olivier; Baris Turak; A Devaux; René Pumain; Massimo Avoli
GABAA receptor-dependent synchronization leads to ictogenesis in the human dysplastic cortex.
Brain : a journal of neurology 2004;127(Pt 7):1626-40.
2004: Rüdiger Köhling; Uwe-Robert Koch; Melanie Hamann; Angelika Richter
Increased excitability in cortico-striatal synaptic pathway in a model of paroxysmal dystonia.
Neurobiology of disease 2004;16(1):236-45.
2004: Christiane Rüschenschmidt; Rüdiger Köhling; M Schwarz; Heidrun Straub; Ali Gorji; Elke Siep; alois ebner; Heinz Wolfgang Pannek; Ingrid Tuxhorn; Peter Wolf; Erwin-Josef Speckmann
Characterization of a fast transient outward current in neocortical neurons from epilepsy patients.
Journal of neuroscience research 2004;75(6):807-16.
2004: W Vollmar; J Gloger; E Berger; G Kortenbruck; Rüdiger Köhling; Erwin-Josef Speckmann; Ulrich Musshoff
RNA editing (R/G site) and flip-flop splicing of the AMPA receptor subunit GluR2 in nervous tissue of epilepsy patients.
Neurobiology of disease 2004;15(2):371-9.
2004: Iskender Teber; Rüdiger Köhling; Erwin-Josef Speckmann; Angelika Barnekow; Joachim Kremerskothen
Muscarinic acetylcholine receptor stimulation induces expression of the activity-regulated cytoskeleton-associated gene (ARC).
Brain research. Molecular brain research 2004;121(1-2):131-6.
2004: Volker Senner; Rüdiger Köhling; Sylvia Püttmann-Cyrus; Heidrun Straub; Werner Paulus; Erwin-Josef Speckmann
A new neurophysiological/neuropathological ex vivo model localizes the origin of glioma-associated epileptogenesis in the invasion area.
Acta neuropathologica 2004;107(1):1-7.
2003: Rüdiger Köhling; Uwe-Robert Koch; Georg Hagemann; Christoph Redecker; Heidrun Straub; Erwin-Josef Speckmann
Differential sensitivity to induction of spreading depression by partial disinhibition in chronically epileptic human and rat as compared to native rat neocortical tissue.
Brain research 2003;975(1-2):129-34.
2003: Christoph Greiner; Johannes Wölfer; Swen Hülsmann; Sampsa Vanhatalo; Rüdiger Köhling; Heinz Wolfgang Pannek; Erwin-Josef Speckmann; Hansdetlef Wassmann
Bioelectrical behaviour of hypoxic human neocortical tissue under the influence of nimodipine and dimethyl sulfoxide.
Brain research 2003;959(2):199-205.
2003: Heidrun Straub; U Kuhnt; Jorg-Michael Höhling; Rüdiger Köhling; Ali Gorji; D Kuhlmann; Ingrid Tuxhorn; alois ebner; Peter Wolf; Heinz Wolfgang Pannek; Rainer Lahl; Erwin-Josef Speckmann
Stimulus-induced patterns of bioelectric activity in human neocortical tissue recorded by a voltage sensitive dye.
Neuroscience 2003;121(3):587-604.
2002: Ali Gorji; Jorg-Michael Höhling; Michael Madeja; Heidrun Straub; Rüdiger Köhling; Ingrid Tuxhorn; alois ebner; Peter Wolf; H W Panneck; Friedrich Behne; Rainer Lahl; Erwin-Josef Speckmann
Effect of levetiracetam on epileptiform discharges in human neocortical slices.
Epilepsia 2002;43(12):1480-7.
2002: Rüdiger Köhling; Klaus König; Anne Lücke; Thomas Mayer; Peter Wolf; Erwin-Josef Speckmann
Pre- rather than co-application of vigabatrin increases the efficacy of tiagabine in hippocampal slices.
Epilepsia 2002;43(12):1455-61.
2002: Rüdiger Köhling
Neuroscience. GABA becomes exciting.
Science (New York, N.Y.) 2002;298(5597):1350-1.
2002: Rüdiger Köhling
Voltage-gated sodium channels in epilepsy.
Epilepsia 2002;43(11):1278-95.
2002: Massimo Avoli; Margherita D'Antuono; Jacques Louvel; Rüdiger Köhling; Giuseppe Biagini; René Pumain; Giovanna D'Arcangelo; Virginia Tancredi
Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro.
Progress in neurobiology 2002;68(3):167-207.
2002: Christoph Greiner; Johannes Wölfer; Hansdetlef Wassmann; Rüdiger Köhling; Erwin-Josef Speckmann
Effects of methohexital on bioelectrical reactions in guinea pig hippocampal slices during hypoxia.
Neuroscience letters 2002;329(2):227-31.
2002: Elke Siep; A Richter; Wolfgang Löscher; Erwin-Josef Speckmann; Rüdiger Köhling
Sodium currents in striatal neurons from dystonic dt(sz) hamsters: altered response to lamotrigine.
Neurobiology of disease 2002;9(2):258-68.
2002: Rüdiger Köhling; J Reinel; J Vahrenhold; K Hinrichs; Erwin-Josef Speckmann
Spatio-temporal patterns of neuronal activity: analysis of optical imaging data using geometric shape matching.
Journal of neuroscience methods 2002;114(1):17-23.
2002: Marom Bikson; R Id Bihi; Martin Vreugdenhil; Rüdiger Köhling; John E Fox; John Jefferys
Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro.
Neuroscience 2002;115(1):251-61.
2001: Ali Gorji; Michael Madeja; Heidrun Straub; Rüdiger Köhling; Erwin-Josef Speckmann
Lowering of the potassium concentration induces epileptiform activity in guinea-pig hippocampal slices.
Brain research 2001;908(2):130-9.
2001: Ali Gorji; DK Scheller; Heidrun Straub; F Tegtmeier; Rüdiger Köhling; Jorg-Michael Höhling; Ingrid Tuxhorn; alois ebner; Peter Wolf; H Werner Panneck; F Oppel; Erwin-Josef Speckmann
Spreading depression in human neocortical slices.
Brain research 2001;906(1-2):74-83.
2001: Heidrun Straub; Rüdiger Köhling; Jorg-Michael Höhling; C Rundfeldt; Ingrid Tuxhorn; alois ebner; Peter Wolf; Heinz Wolfgang Pannek; Erwin-Josef Speckmann
Effects of retigabine on rhythmic synchronous activity of human neocortical slices.
Epilepsy research 2001;44(2-3):155-65.
2001: Ali Gorji; Rüdiger Köhling; Heidrun Straub; Jorg-Michael Höhling; Michael Madeja
Lowering the extracellular potassium concentration elicits epileptic activity in neocortical tissue of epileptic patients.
The European journal of neuroscience 2001;13(3):639-40.
2001: Rüdiger Köhling; SJ Gladwell; Enrico Bracci; Martin Vreugdenhil; John Jefferys
Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling.
Neuroscience 2001;105(3):579-87.
2000: Christoph Greiner; A Schmidinger; Swen Hülsmann; Dag Moskopp; Johannes Wölfer; Rüdiger Köhling; Erwin-Josef Speckmann; Hansdetlef Wassmann
Acute protective effect of nimodipine and dimethyl sulfoxide against hypoxic and ischemic damage in brain slices.
Brain research 2000;887(2):316-22.
2000: Dieter Bingmann; Martin Wiemann; Erwin-Josef Speckmann; Rüdiger Köhling; Heidrun Straub; K Dunze; Werner Wittkowski
Cutting of living hippocampal slices by a highly pressurised water jet (macromingotome).
Journal of neuroscience methods 2000;102(1):1-9.
2000: Ali Gorji; DK Scheller; F Tegtmeier; Rüdiger Köhling; Heidrun Straub; Erwin-Josef Speckmann
NiCl2 and amiloride induce spreading depression in guinea pig hippocampal slices.
Cephalalgia : an international journal of headache 2000;20(8):740-7.
2000: Rüdiger Köhling; Jorg-Michael Höhling; Heidrun Straub; D Kuhlmann; U Kuhnt; Ingrid Tuxhorn; alois ebner; Peter Wolf; Heinz Wolfgang Pannek; Ali Gorji; Erwin-Josef Speckmann
Optical monitoring of neuronal activity during spontaneous sharp waves in chronically epileptic human neocortical tissue.
Journal of neurophysiology 2000;84(4):2161-5.
2000: Rüdiger Köhling; Martin Vreugdenhil; Enrico Bracci; John Jefferys
Ictal epileptiform activity is facilitated by hippocampal GABAA receptor-mediated oscillations.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(18):6820-9.
2000: Ulrich Musshoff; Rüdiger Köhling; Anne Lücke; Erwin-Josef Speckmann; Ingrid Tuxhorn; Peter Wolf; H W Pauuek; F Oppel
Vigabatrin reduces epileptiform activity in brain slices from pharmacoresistant epilepsy patients.
European journal of pharmacology 2000;401(2):167-72.
2000: Rüdiger Köhling; Heidrun Straub; Erwin-Josef Speckmann
Differential involvement of L-type calcium channels in epileptogenesis of rat hippocampal slices during ontogenesis.
Neurobiology of disease 2000;7(4):471-82.
2000: Ulrich Musshoff; U Schünke; Rüdiger Köhling; Erwin-Josef Speckmann
Alternative splicing of the NMDAR1 glutamate receptor subunit in human temporal lobe epilepsy.
Brain research. Molecular brain research 2000;76(2):377-84.
2000: Heidrun Straub; Jorg-Michael Höhling; Rüdiger Köhling; Anne Lücke; Ingrid Tuxhorn; alois ebner; Peter Wolf; Heinz Wolfgang Pannek; F Oppel; Erwin-Josef Speckmann
Effects of nifedipine on rhythmic synchronous activity of human neocortical slices.
Neuroscience 2000;100(3):445-52.
2000: Heidrun Straub; Rüdiger Köhling; A Frieler; M Grigat; Erwin-Josef Speckmann
Contribution of L-type calcium channels to epileptiform activity in hippocampal and neocortical slices of guinea-pigs.
Neuroscience 2000;95(1):63-72.
1999: Swen Hülsmann; Rüdiger Köhling; Christoph Greiner; Dag Moskopp; Anne Lücke; Hansdetlef Wassmann; Erwin-Josef Speckmann
Neuroprotection by 21-aminosteroids: insights from latencies of anoxic terminal negativity in hippocampus slices of guinea pig.
Neurological research 1999;21(3):305-8.
1999: Swen Hülsmann; Christoph Greiner; Rüdiger Köhling; Johannes Wölfer; Dag Moskopp; Burkhard Riemann; Anne Lücke; Hansdetlef Wassmann; Erwin-Josef Speckmann
Dimethyl sulfoxide increases latency of anoxic terminal negativity in hippocampal slices of guinea pig in vitro.
Neuroscience letters 1999;261(1-2):1-4.
1999: Karl Zilles; MS Qü; Rüdiger Köhling; Erwin-Josef Speckmann
Ionotropic glutamate and GABA receptors in human epileptic neocortical tissue: quantitative in vitro receptor autoradiography.
Neuroscience 1999;94(4):1051-61.
1999: Rüdiger Köhling; MS Qü; Karl Zilles; Erwin-Josef Speckmann
Current-source-density profiles associated with sharp waves in human epileptic neocortical tissue.
Neuroscience 1999;94(4):1039-50.
1998: Rüdiger Köhling; Christoph Greiner; Johannes Wölfer; Hansdetlef Wassmann; Erwin-Josef Speckmann
Optical monitoring of PO2 changes and simultaneous recording of bioelectric activity in human and animal brain slices.
Journal of neuroscience methods 1998;85(2):181-6.
1998: B Albowitz; U Kuhnt; Rüdiger Köhling; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann; Ingrid Tuxhorn; Peter Wolf; Heinz Wolfgang Pannek; F Oppel
Spatio-temporal distribution of epileptiform activity in slices from human neocortex: recordings with voltage-sensitive dyes.
Epilepsy research 1998;32(1-2):224-32.
1998: Erwin-Josef Speckmann; Rüdiger Köhling; Anne Lücke; Heidrun Straub; Werner Wittkowski; C E Elger; Martin Wiemann; Dieter Bingmann
Microcutting of living brain slices by a pulsed ultrafine water jet which allows simultaneous electrophysiological recordings (micromingotome).
Journal of neuroscience methods 1998;82(1):53-8.
1998: Rüdiger Köhling; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann; I Tuxhorn; P Wolf; Heinz Wolfgang Pannek; F Oppel
Spontaneous sharp waves in human neocortical slices excised from epileptic patients.
Brain : a journal of neurology 1998;121 ( Pt 6)():1073-87.
1998: A Schmidinger; Christoph Greiner; S Reinker; Rüdiger Köhling; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann; Dag Moskopp; Hansdetlef Wassmann; Rainer Lahl; Heinz Wolfgang Pannek; F Oppel
Flat and steep terminal negativity in the DC-potential after deprivation of oxygen and glucose in human neocortical slices.
Brain research 1998;794(1):28-34.
1998: Anne Lücke; Ulrich Musshoff; Rüdiger Köhling; M Osterfeld; T Mayer; Peter Wolf; W Schütte; Erwin-Josef Speckmann
Gabapentin potentiation of the antiepileptic efficacy of vigabatrin in an in vitro model of epilepsy.
British journal of pharmacology 1998;124(2):370-6.
1998: Christoph Greiner; Swen Hülsmann; Hansdetlef Wassmann; Dag Moskopp; A Schmidinger; Johannes Wölfer; Rüdiger Köhling; Anne Lücke; Erwin-Josef Speckmann
Neuroprotection of mild hypothermia: differential effects.
Brain research 1998;786(1-2):267-9.
1997: Heidrun Straub; Rüdiger Köhling; Erwin-Josef Speckmann
Strychnine-induced epileptiform activity in hippocampal and neocortical slice preparations: suppression by the organic calcium antagonists verapamil and flunarizine.
Brain research 1997;773(1-2):173-80.
1996: Massimo Avoli; Rüdiger Köhling; Michaela Barbarosie
Anoxia blocks the presynaptic control of GABA release at inhibitory terminals in the rat hippocampus.
Neuroscience 1996;75(4):999-1002.
1996: Rüdiger Köhling; A Schmidinger; Swen Hülsmann; S Vanhatalo; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann; Ingrid Tuxhorn; Peter Wolf; R Lahl; Heinz Wolfgang Pannek; F Oppel; Christoph Greiner; Dag Moskopp; Hansdetlef Wassmann
Anoxic terminal negative DC-shift in human neocortical slices in vitro.
Brain research 1996;741(1-2):174-9.
1996: Massimo Avoli; T Nagao; Rüdiger Köhling; Anne Lücke; D Mattia
Synchronization of rat hippocampal neurons in the absence of excitatory amino acid-mediated transmission.
Brain research 1996;735(2):188-96.
1996: Anne Lücke; Rüdiger Köhling; Erwin-Josef Speckmann
Effects of glutamate application on the rhythm of low magnesium-induced epileptiform activity in hippocampal slices of guinea-pigs.
The European journal of neuroscience 1996;8(10):2137-48.
1996: Heidrun Straub; Rüdiger Köhling; A Lüke; Jan-Dirk Fauteck; Erwin-Josef Speckmann; Dag Moskopp; Hansdetlef Wassmann; Ingrid Tuxhorn; Peter Wolf; Heinz Wolfgang Pannek; F Oppel
The effects of verapamil and flunarizine on epileptiform activity induced by bicuculline and low Mg2+ in neocortical tissue of epileptic and primary non-epileptic patients.
Brain research 1996;733(2):307-11.
1996: Hansdetlef Wassmann; Dag Moskopp; B Woesler; Anne Lücke; Erwin-Josef Speckmann; Rüdiger Köhling; Heidrun Straub; Swen Hülsmann; Christoph Greiner
Repetitive hypoxic exposure of brain slices and electrophysiological responses as an experimental model for investigation of cerebroprotective measurements.
Neurological research 1996;18(4):367-9.
1996: Rüdiger Köhling; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann
A portable chamber for long-distance transport of surviving human brain slice preparations.
Journal of neuroscience methods 1996;67(2):233-6.
1996: Massimo Avoli; Michaela Barbarosie; Anne Lücke; T Nagao; V Lopantsev; Rüdiger Köhling
Synchronous GABA-mediated potentials and epileptiform discharges in the rat limbic system in vitro.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(12):3912-24.
1995: Rüdiger Köhling; Anne Lücke; T Nagao; E J Speckmann; Massimo Avoli
Extracellular potassium elevations in the hippocampus of rats with long-term pilocarpine seizures.
Neuroscience letters 1995;201(1):87-91.
1995: Anne Lücke; T Nagao; Rüdiger Köhling; Massimo Avoli
Synchronous potentials and elevations in [K+]o in the adult rat entorhinal cortex maintained in vitro.
Neuroscience letters 1995;185(3):155-8.
1995: Anne Lücke; Rüdiger Köhling; Heidrun Straub; Dag Moskopp; Hansdetlef Wassmann; Erwin-Josef Speckmann
Changes of extracellular calcium concentration induced by application of excitatory amino acids in the human neocortex in vitro.
Brain research 1995;671(2):222-6.
1995: Jan-Dirk Fauteck; Jürgen Bockmann; Tobias M Böckers; Werner Wittkowski; Rüdiger Köhling; Anne Lücke; Heidrun Straub; Erwin-Josef Speckmann; Ingrid Tuxhorn; Peter Wolf
Melatonin reduces low-Mg2+ epileptiform activity in human temporal slices.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1995;107(2):321-5.
1994: Heidrun Straub; Rüdiger Köhling; Erwin-Josef Speckmann
Picrotoxin-induced epileptic activity in hippocampal and neocortical slices (guinea pig): suppression by organic calcium channel blockers.
Brain research 1994;658(1-2):119-26.
1994: Andreas Schulze-Bonhage; Rüdiger Köhling; Heidrun Straub; Erwin-Josef Speckmann
Flunarizine shows increased antiepileptic efficacy with elevated K+ levels in low magnesium induced epileptic activity (neocortical slices, guinea pig).
Neuropharmacology 1994;33(5):613-8.
1994: Rüdiger Köhling; Heidrun Straub; Erwin-Josef Speckmann
Spontaneous and stimulus-triggered epileptic discharges: delayed antiepileptic effect with triggering.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1994;100(3):376-84.
1993: Rüdiger Köhling; A Lehmenkükhler; C Nicholson; Erwin-Josef Speckmann
Superfusion of verapamil on the cerebral cortex does not suppress epileptic discharges due to restricted diffusion (rats, in vivo).
Brain research 1993;626(1-2):149-55.
1993: E J Speckmann; H Straub; Rüdiger Köhling
Contribution of calcium ions to the generation of epileptic activity and antiepileptic calcium antagonism.
Neuropsychobiology 1993;27(3):122-6.
1992: Heidrun Straub; Rüdiger Köhling; Erwin-Josef Speckmann
Low magnesium induced epileptiform discharges in neocortical slices (guinea pig): increased antiepileptic efficacy of organic calcium antagonist verapamil with elevation of extracellular K+ concentration.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1992;103(1):57-63.