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Dirk Linke

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Marcus Hartmann; Silvia Deiss; Stanislaw Dunin-Horkawicz; Iwan Grin; Dirk Linke; Andrei N Lupas; Birte Hernandez Alvarez
Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria.
Shakeel Ahmad Shahid; Barth-Jan van Rossum; Benjamin Bardiaux; W Trent Franks; Michael Habeck; Ludwig Krabben; Dirk Linke
Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals.
Jack C Leo; Iwan Grin; Dirk Linke
Type V secretion: mechanism(s) of autotransport through the bacterial outer membrane.

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All Publications

2012: Marcus Hartmann; Silvia Deiss; Stanislaw Dunin-Horkawicz; Iwan Grin; Dirk Linke; Andrei N Lupas; Birte Hernandez Alvarez
Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(51):20907-12.
2012: Shakeel Ahmad Shahid; Barth-Jan van Rossum; Benjamin Bardiaux; W Trent Franks; Michael Habeck; Ludwig Krabben; Dirk Linke
Membrane-protein structure determination by solid-state NMR spectroscopy of microcrystals.
Nature methods 2012;9(12):1212-7.
2012: Jack C Leo; Iwan Grin; Dirk Linke
Type V secretion: mechanism(s) of autotransport through the bacterial outer membrane.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2012;367(1592):1088-101.
2012: Maren Paulmann; Thomas Arnold; Jochen Bürck; Thomas Gutsmann; Michael Habeck; Hubert Kalbacher; Annika Kopp; Dirk Linke; Verena J Schuenemann; Anne S Ulrich; Ines Wanke; Suat Ozdirekcan; Birgit Schittek
Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide present in human sweat.
The Journal of biological chemistry 2012;287(11):8434-43.
2012: Patrick O Kaiser; Jack C Leo; Dirk Linke; Heinz Schwarz; Volkhard A J Kempf
Analysis of the BadA stalk from Bartonella henselae reveals domain-specific and domain-overlapping functions in the host cell infection process.
Cellular microbiology 2012;14(2):198-209.
2012: Shakeel A Shahid; Dirk Linke; Stefan Markovic; Barth-Jan van Rossum
Assignment and secondary structure of the YadA membrane protein by solid-state MAS NMR.
Scientific reports 2012;2():803.
2012: Philipp Oberhettinger; Monika Schütz; Ingo B Autenrieth; Jürgen Berger; Nadja Heinz; Jack C Leo; Dirk Linke
Intimin and invasin export their C-terminus to the bacterial cell surface using an inverse mechanism compared to classical autotransport.
PloS one 2012;7(10):e47069.
2012: Nagarajan Paramasivam; Michael Habeck; Dirk Linke
Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not?
BMC genomics 2012;13():510.
2011: Dennis Gessmann; Jie Liang; Dirk Linke; Frauke Mager; Hammad Naveed; Thomas Arnold; Sara Weirich; Stephan Nussberger
Improving the resistance of a eukaryotic β-barrel protein to thermal and chemical perturbations.
Journal of molecular biology 2011;413(1):150-61.
2011: Carolin Wagner; Roman G Gerlach; Dirk Linke; Melanie Polke; Heinz Schwarz; York-Dieter Stierhof; Michael Hensel
Functional dissection of SiiE, a giant non-fimbrial adhesin of Salmonella enterica.
Cellular microbiology 2011;13(8):1286-301.
2011: Iwan Grin; Dirk Linke
GCView: the genomic context viewer for protein homology searches.
Nucleic acids research 2011;39(Web Server issue):W353-6.
2011: Niklas F Müller; Tanja Riess; Andrea Schäfer; Heinz Schwarz; Johannes A Eble; Patrick O Kaiser; Dirk Linke; Volkhard A J Kempf
Trimeric autotransporter adhesin-dependent adherence of Bartonella henselae, Bartonella quintana, and Yersinia enterocolitica to matrix components and endothelial cells under static and dynamic flow conditions.
Infection and immunity 2011;79(7):2544-53.
2011: Jutta Vogelmann; Moritz Ammelburg; Constanze Finger; Jamil Guezguez; Dirk Linke; Matthias Floetenmeyer; York-Dieter Stierhof; Wolfgang Wohlleben; Günther Muth
Conjugal plasmid transfer in Streptomyces resembles bacterial chromosome segregation by FtsK/SpoIIIE.
The EMBO journal 2011;30(11):2246-54.
2011: Nagarajan Paramasivam; Dirk Linke
ClubSub-P: Cluster-Based Subcellular Localization Prediction for Gram-Negative Bacteria and Archaea.
Frontiers in microbiology 2011;2():218.
2011: Iwan Grin; Heinz Schwarz; Dirk Linke
Electron microscopy techniques to study bacterial adhesion.
Advances in experimental medicine and biology 2011;715():257-69.
2011: Fiona O'Rourke; Thomas Schmidgen; Patrick O Kaiser; Dirk Linke; Volkhard A J Kempf
Adhesins of Bartonella spp.
Advances in experimental medicine and biology 2011;715():51-70.
2011: Philipp Oberhettinger; Monika Schütz; Günter Raddatz; Heike Keller; Ingo B Autenrieth; Dirk Linke
The sequence of the pYV virulence plasmid from Yersinia enterocolitica strain WA-314 biogroup 1B serotype O:8.
Plasmid 2011;65(1):20-4.
2011: Patrick O Kaiser; Tanja Riess; Fiona O'Rourke; Dirk Linke; Volkhard A J Kempf
Bartonella spp.: throwing light on uncommon human infections.
International journal of medical microbiology : IJMM 2011;301(1):7-15.
2010: Marcus Thein; Guido Sauer; Nagarajan Paramasivam; Iwan Grin; Dirk Linke
Efficient subfractionation of gram-negative bacteria for proteomics studies.
Journal of proteome research 2010;9(12):6135-47.
2010: U Lehr; M Schütz; P Oberhettinger; Fernando Ruiz-Perez; J W Donald; T Palmer; Dirk Linke; I R Henderson; Ingo B Autenrieth
C-terminal amino acid residues of the trimeric autotransporter adhesin YadA of Yersinia enterocolitica are decisive for its recognition and assembly by BamA.
Molecular microbiology 2010;78(4):932-46.
2010: Thomas Arnold; Kornelius Zeth; Dirk Linke
Omp85 from the thermophilic cyanobacterium Thermosynechococcus elongatus differs from proteobacterial Omp85 in structure and domain composition.
The Journal of biological chemistry 2010;285(23):18003-15.
2010: M Schütz; E-M Weiss; M Schindler; T Hallström; P F Zipfel; Dirk Linke; Ingo B Autenrieth
Trimer stability of YadA is critical for virulence of Yersinia enterocolitica.
Infection and immunity 2010;78(6):2677-90.
2010: M Remmert; A Biegert; Dirk Linke; A N Lupas; J Söding
Evolution of outer membrane beta-barrels from an ancestral beta beta hairpin.
Molecular biology and evolution 2010;27(6):1348-58.
2010: Michaela Norum; Erika Tång; Tina Chavoshi; Heinz Schwarz; Dirk Linke; Anne Uv; Bernard Moussian
Trafficking through COPII stabilises cell polarity and drives secretion during Drosophila epidermal differentiation.
PloS one 2010;5(5):e10802.
2009: Dirk Linke
Commentary: Never trust your word processor.
Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 2009;37(6):377.
2009: Nicolas Rohner; Miklós Bercsényi; Laszlo Orban; Maria E Kolanczyk; Dirk Linke; Michael Brand; Christiane Nüsslein-Volhard; Matthew P Harris
Duplication of fgfr1 permits Fgf signaling to serve as a target for selection during domestication.
Current biology : CB 2009;19(19):1642-7.
2009: Sabine Gröbner; Dirk Linke; Wolfgang Schütz; Claudia Fladerer; Johannes Madlung; Ingo B Autenrieth; Wolfgang Witte; Yvonne Pfeifer
Emergence of carbapenem-non-susceptible extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates at the university hospital of Tübingen, Germany.
Journal of medical microbiology 2009;58(Pt 7):912-22.
2009: Michael Remmert; Dirk Linke; Andrei N Lupas; Johannes Söding
HHomp--prediction and classification of outer membrane proteins.
Nucleic acids research 2009;37(Web Server issue):W446-51.
2009: Thomas Arnold; Kornelius Zeth; Dirk Linke
Structure and function of colicin S4, a colicin with a duplicated receptor-binding domain.
The Journal of biological chemistry 2009;284(10):6403-13.
2009: Dirk Linke
Detergents: an overview.
Methods in enzymology 2009;463():603-17.
2008: Patrick O Kaiser; Tanja Riess; Carola L Wagner; Dirk Linke; Andrei N Lupas; Heinz Schwarz; Günter Raddatz; Andrea Schäfer; Volkhard A J Kempf
The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae.
Cellular microbiology 2008;10(11):2223-34.
2008: Carola L Wagner; Tanja Riess; Dirk Linke; Christian Eberhardt; Andrea Schäfer; Sabine Reutter; Ricardo Maggi; Volkhard A J Kempf
Use of Bartonella adhesin A (BadA) immunoblotting in the serodiagnosis of Bartonella henselae infections.
International journal of medical microbiology : IJMM 2008;298(7-8):579-90.
2008: Thomas Arnold; Dirk Linke
The use of detergents to purify membrane proteins.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2008;Chapter 4():Unit 4.8.1-4.8.30.
2008: Pawel Szczesny; Dirk Linke; Astrid Ursinus; Kerstin Bär; Heinz Schwarz; Tanja M Riess; Volkhard A J Kempf; Andrei N Lupas; Jörg Martin; Kornelius Zeth
Structure of the head of the Bartonella adhesin BadA.
PLoS pathogens 2008;4(8):e1000119.
2008: Birte Hernandez Alvarez; Marcus Hartmann; Reinhard Albrecht; Andrei N Lupas; Kornelius Zeth; Dirk Linke
A new expression system for protein crystallization using trimeric coiled-coil adaptors.
Protein engineering, design & selection : PEDS 2008;21(1):11-8.
2007: Ulrike Grosskinsky; Monika Schütz; Michaela Fritz; Yvonne Schmid; Marina C Lamparter; Pawel Szczesny; Andrei N Lupas; Ingo B Autenrieth; Dirk Linke
A conserved glycine residue of trimeric autotransporter domains plays a key role in Yersinia adhesin A autotransport.
Journal of bacteriology 2007;189(24):9011-9.
2007: Thomas Arnold; Dirk Linke
Phase separation in the isolation and purification of membrane proteins.
BioTechniques 2007;43(4):427-30, 432, 434 passim.
2007: Nai-Hua Hsiao; Johannes Söding; Dirk Linke; Corinna Lange; Christian Hertweck; Wolfgang Wohlleben; Eriko Takano
ScbA from Streptomyces coelicolor A3(2) has homology to fatty acid synthases and is able to synthesize gamma-butyrolactones.
Microbiology (Reading, England) 2007;153(Pt 5):1394-404.
2007: Thomas Arnold; Melissa Poynor; Stephan Nussberger; Andrei N Lupas; Dirk Linke
Gene duplication of the eight-stranded beta-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane beta-barrels.
Journal of molecular biology 2007;366(4):1174-84.
2007: Tanja Riess; Günter Raddatz; Dirk Linke; Andrea Schäfer; Volkhard A J Kempf
Analysis of Bartonella adhesin A expression reveals differences between various B. henselae strains.
Infection and immunity 2007;75(1):35-43.
2006: Berit Schulte; Dirk Linke; Sandra Klumpp; Martin Schaller; Tanja Riess; Ingo B Autenrieth; Volkhard A J Kempf
Bartonella quintana variably expressed outer membrane proteins mediate vascular endothelial growth factor secretion but not host cell adherence.
Infection and immunity 2006;74(9):5003-13.
2006: Petra Wollmann; Kornelius Zeth; Andrei N Lupas; Dirk Linke
Purification of the YadA membrane anchor for secondary structure analysis and crystallization.
International journal of biological macromolecules 2006;39(1-3):3-9.
2006: Dirk Linke; Tanja Riess; Ingo B Autenrieth; Andrei N Lupas; Volkhard A J Kempf
Trimeric autotransporter adhesins: variable structure, common function.
Trends in microbiology 2006;14(6):264-70.
2006: Reinhard Albrecht; Kornelius Zeth; Johannes Söding; Andrei N Lupas; Dirk Linke
Expression, crystallization and preliminary X-ray crystallographic studies of the outer membrane protein OmpW from Escherichia coli.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 4):415-8.
2004: Dirk Linke; Joachim Frank; Matthew S Pope; Jürgen Soll; Iryna Ilkavets; Petra Fromme; Edward A Burstein; Yana K Reshetnyak; Victor I Emelyanenko
Folding kinetics and structure of OEP16.
Biophysical journal 2004;86(3):1479-87.
2000: Dirk Linke; Joachim Frank; Josef F Holzwarth; J Soll; C Boettcher; Petra Fromme
In vitro reconstitution and biophysical characterization of OEP16, an outer envelope pore protein of pea chloroplasts.
Biochemistry 2000;39(36):11050-6.
2000: T Strauss; Alfred Botha; Johan L F Kock; I Paul; DP Smith; Dirk Linke; Tankred Schewe; Santosh Nigam
Mapping the distribution of 3-hydroxylipins in the Mucorales using immunofluorescence microscopy.
Antonie van Leeuwenhoek 2000;78(1):39-42.
1998: Johan L F Kock; P Venter; Dirk Linke; Tankred Schewe; Santosh Nigam
Biological dynamics and distribution of 3-hydroxy fatty acids in the yeast Dipodascopsis uninucleata as investigated by immunofluorescence microscopy. Evidence for a putative regulatory role in the sexual reproductive cycle.
FEBS letters 1998;427(3):345-8.
1998: B Essigmann; S Güler; R A Narang; Dirk Linke; Christoph Benning
Phosphate availability affects the thylakoid lipid composition and the expression of SQD1, a gene required for sulfolipid biosynthesis in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1950-5.