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Jeffrey Pessin

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Claire Bastie; Elena Dhima; Erin Gaffney-Stomberg; Ting-Wen A Lee; Jeffrey Pessin; Leonard H Augenlicht
Dietary cholecalciferol and calcium levels in a Western-style defined rodent diet alter energy metabolism and inflammatory responses in mice.
Susmita Kaushik; Hyok Joon Kwon; Nuria Martinez Lopez; Jeffrey Pessin; Srabani Sahu; Gary J Schwartz; Esperanza Arias; Diana Athonvarangkul; Rajat Singh
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
Haihong Zong; Michal Armoni; Chava Harel; Eddy Karnieli; Jeffrey Pessin
Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance.

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2012: Claire Bastie; Elena Dhima; Erin Gaffney-Stomberg; Ting-Wen A Lee; Jeffrey Pessin; Leonard H Augenlicht
Dietary cholecalciferol and calcium levels in a Western-style defined rodent diet alter energy metabolism and inflammatory responses in mice.
The Journal of nutrition 2012;142(5):859-65.
2012: Susmita Kaushik; Hyok Joon Kwon; Nuria Martinez Lopez; Jeffrey Pessin; Srabani Sahu; Gary J Schwartz; Esperanza Arias; Diana Athonvarangkul; Rajat Singh
Loss of autophagy in hypothalamic POMC neurons impairs lipolysis.
EMBO reports 2012;13(3):258-65.
2012: Haihong Zong; Michal Armoni; Chava Harel; Eddy Karnieli; Jeffrey Pessin
Cytochrome P-450 CYP2E1 knockout mice are protected against high-fat diet-induced obesity and insulin resistance.
American journal of physiology. Endocrinology and metabolism 2012;302(5):E532-9.
2012: Manu Vatish; Eijiro Yamada; Claire Bastie; dimitris grammatopoulos; Lydia Tesfa; Jeffrey Pessin
Inhibition of Akt activity and calcium channel function coordinately drive cell-cell fusion in the BeWO choriocarcinoma placental cell line.
PloS one 2012;7(1):e29353.
2011: Atsushi Nohara; Kihachi Ohshima; Shuichi Okada; Jeffrey Pessin; Masatomo Mori
Cyclin-dependent kinase-5 is a key molecule in tumor necrosis factor-α-induced insulin resistance.
The Journal of biological chemistry 2011;286(38):33457-65.
2011: Daorong Feng; Meredith Hawkins; Richard N Kitsis; Hyok Joon Kwon; Yan Tang; Haihong Zong; Jeffrey Pessin
High-fat diet-induced adipocyte cell death occurs through a cyclophilin D intrinsic signaling pathway independent of adipose tissue inflammation.
Diabetes 2011;60(8):2134-43.
2011: Laura Cheney; June C Hou; Sidonie Morrison; Jeffrey Pessin; Roy T Steigbigel
Nef inhibits glucose uptake in adipocytes and contributes to insulin resistance in human immunodeficiency virus type I infection.
The Journal of infectious diseases 2011;203(12):1824-31.
2011: Ping Huang; Oladapo Yeku; Haihong Zong; Phyllis Tsang; Wenjuan Su; Xiao Yu; Shuzhi Teng; Mary Osisami; Yasunori Kanaho; Jeffrey Pessin; Michael A Frohman
Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice.
Diabetes 2011;60(2):454-63.
2011: Haihong Zong; Cheng-Chun Wang; Bhavapriya Vaitheesvaran; Irwin Kurland; Wanjin Hong; Jeffrey Pessin
Enhanced energy expenditure, glucose utilization, and insulin sensitivity in VAMP8 null mice.
Diabetes 2011;60(1):30-8.
2010: Eijiro Yamada; Ting-Wen A Lee; Jeffrey Pessin; Claire Bastie
Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance.
Future medicinal chemistry 2010;2(12):1785-96.
2010: Jennifer Pfaffly; Michael Michaelides; Gene-Jack Wang; Jeffrey Pessin; Nora D Volkow; Panayotis K Thanos
Leptin increases striatal dopamine D2 receptor binding in leptin-deficient obese (ob/ob) mice.
Synapse (New York, N.Y.) 2010;64(7):503-10.
2010: Pingping Li; Min Lu; M T Audrey Nguyen; Eun Ju Bae; Justin Chapman; Daorong Feng; Meredith Hawkins; Jeffrey Pessin; Dorothy D Sears; Anh-Khoi Nguyen; Arezou Amidi; Steven M Watkins; Uyenthao Nguyen; Jerrold M Olefsky
Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.
The Journal of biological chemistry 2010;285(20):15333-45.
2010: Eijiro Yamada; Jeffrey Pessin; Irwin Kurland; Gary J Schwartz; Claire Bastie
Fyn-dependent regulation of energy expenditure and body weight is mediated by tyrosine phosphorylation of LKB1.
Cell metabolism 2010;11(2):113-24.
2010: Encarnación Capilla; Mònica Díaz; June Chunqiu Hou; Josep V Planas; Jeffrey Pessin
High basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes.
American journal of physiology. Endocrinology and metabolism 2010;298(2):E329-36.
2010: Yen K Luu; E Ozcivici; Encarnación Capilla; B Adler; E Chan; K Shroyer; Janet Rubin; Stefan Judex; Jeffrey Pessin; C T Rubin
Development of diet-induced fatty liver disease in the aging mouse is suppressed by brief daily exposure to low-magnitude mechanical signals.
International journal of obesity (2005) 2010;34(2):401-5.
2010: Maria D'Apolito; Xue-Liang Du; Haihong Zong; Alessandra Catucci; Luigi Maiuri; Tiziana Trivisano; Massimo Pettoello-Mantovani; Angelo Campanozzi; Valeria Raia; Jeffrey Pessin; Michael Brownlee; Ida Giardino
Urea-induced ROS generation causes insulin resistance in mice with chronic renal failure.
The Journal of clinical investigation 2010;120(1):203-13.
2010: Alejandra Tomas; Barbara Yermen; Romano Regazzi; Jeffrey Pessin; Philippe A Halban
Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate.
Traffic (Copenhagen, Denmark) 2010;11(1):123-37.
2009: Dumaine Williams; Jérome Vicôgne; Irina Zaitseva; Stuart McLaughlin; Jeffrey Pessin
Evidence that electrostatic interactions between vesicle-associated membrane protein 2 and acidic phospholipids may modulate the fusion of transport vesicles with the plasma membrane.
Molecular biology of the cell 2009;20(23):4910-9.
2009: Rajat Singh; Youqing Xiang; Yongjun Wang; Kiran Baikati; Ana Maria Cuervo; Yen K Luu; Yan Tang; Jeffrey Pessin; Gary J Schwartz; Mark J Czaja
Autophagy regulates adipose mass and differentiation in mice.
The Journal of clinical investigation 2009;119(11):3329-39.
2009: Manu Vatish; Eijiro Yamada; Jeffrey Pessin; Claire Bastie
Fyn kinase function in lipid utilization: a new upstream regulator of AMPK activity?
Archives of physiology and biochemistry 2009;115(4):191-8.
2009: June Chunqiu Hou; Dumaine Williams; Jérôme Vicogne; Jeffrey Pessin
The glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner.
Endocrinology 2009;150(9):4056-64.
2009: severine groh; Haihong Zong; Matthew M Goddeeris; Connie S Lebakken; David Venzke; Jeffrey Pessin; Kevin P Campbell
Sarcoglycan complex: implications for metabolic defects in muscular dystrophies.
The Journal of biological chemistry 2009;284(29):19178-82.
2009: Ilana Kachko; Adva Maissel; Livnat Mazor; Ronit Ben-Romano; Robert T Watson; June C Hou; Jeffrey Pessin; Nava Bashan; Assaf Rudich
Postreceptoral adipocyte insulin resistance induced by nelfinavir is caused by insensitivity of PKB/Akt to phosphatidylinositol-3,4,5-trisphosphate.
Endocrinology 2009;150(6):2618-26.
2009: Lin V Li; Kyriaki Bakirtzi; Robert T Watson; Jeffrey Pessin; Konstantin V Kandror
The C-terminus of GLUT4 targets the transporter to the perinuclear compartment but not to the insulin-responsive vesicles.
The Biochemical journal 2009;419(1):105-12, 1 p following 112.
2009: Naoko Sasaki-Suzuki; K i Arai; Tomomi Ogata; Kouhei Kasahara; Hideyuki Sakoda; Kazuhiro Chida; Tomoichiro Asano; Jeffrey Pessin; Fumihiko Hakuno; Shin-Ichiro Takahashi
Growth hormone inhibition of glucose uptake in adipocytes occurs without affecting GLUT4 translocation through an insulin receptor substrate-2-phosphatidylinositol 3-kinase-dependent pathway.
The Journal of biological chemistry 2009;284(10):6061-70.
2009: Haihong Zong; Claire Bastie; Jun Xu; Reinhard Fassler; Kevin P Campbell; Irwin Kurland; Jeffrey Pessin
Insulin resistance in striated muscle-specific integrin receptor beta1-deficient mice.
The Journal of biological chemistry 2009;284(7):4679-88.
2009: June Chunqiu Hou; Le Min; Jeffrey Pessin
Insulin granule biogenesis, trafficking and exocytosis.
Vitamins and hormones 2009;80():473-506.
2009: Yen Kim Luu; Encarnacion Capilla; Clifford J Rosen; Vicente Gilsanz; Jeffrey Pessin; Stefan Judex; Clinton T Rubin
Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009;24(1):50-61.
2009: Yen K Luu; S Lublinsky; E Ozcivici; Encarnación Capilla; Jeffrey Pessin; C T Rubin; Stefan Judex
In vivo quantification of subcutaneous and visceral adiposity by micro-computed tomography in a small animal model.
Medical engineering & physics 2009;31(1):34-41.
2008: Shuichi Okada; Eijiro Yamada; Tsugumichi Saito; Kihachi Ohshima; Koshi Hashimoto; Masanobu Yamada; Yutaka Uehara; Takafumi Tsuchiya; Hiroyuki Shimizu; Kazuaki Tatei; Takashi Izumi; Keishi Yamauchi; Shin-Ichi Hisanaga; Jeffrey Pessin; Masatomo Mori
CDK5-dependent phosphorylation of the Rho family GTPase TC10(alpha) regulates insulin-stimulated GLUT4 translocation.
The Journal of biological chemistry 2008;283(51):35455-63.
2008: Giuseppe Procino; Claudia Barbieri; Grazia Tamma; Leonarda De Benedictis; Jeffrey Pessin; Maria Svelto; Giovanna Valenti
AQP2 exocytosis in the renal collecting duct -- involvement of SNARE isoforms and the regulatory role of Munc18b.
Journal of cell science 2008;121(Pt 12):2097-106.
2008: Victor A Drover; David V Nguyen; Claire Bastie; Yolanda F Darlington; Nada A Abumrad; Jeffrey Pessin; Erwin London; Daisy Sahoo; Michael C Phillips
CD36 mediates both cellular uptake of very long chain fatty acids and their intestinal absorption in mice.
The Journal of biological chemistry 2008;283(19):13108-15.
2008: Alejandra Tomas; Paolo Meda; Romano Regazzi; Jeffrey Pessin; Philippe A Halban
Munc 18-1 and granuphilin collaborate during insulin granule exocytosis.
Traffic (Copenhagen, Denmark) 2008;9(5):813-32.
2008: Robert T Watson; June C Hou; Jeffrey Pessin
Recycling of IRAP from the plasma membrane back to the insulin-responsive compartment requires the Q-SNARE syntaxin 6 but not the GGA clathrin adaptors.
Journal of cell science 2008;121(Pt 8):1243-51.
2008: Dumaine Williams; Jeffrey Pessin
Mapping of R-SNARE function at distinct intracellular GLUT4 trafficking steps in adipocytes.
The Journal of cell biology 2008;180(2):375-87.
2008: Jérôme Vicogne; Jeffrey Pessin
SNARE-mediated fusion of liposomes.
Methods in molecular biology (Clifton, N.J.) 2008;457():241-51.
2008: Mitsuhiko Umahara; Shuichi Okada; Eijiro Yamada; Tsugumichi Saito; Kihachi Ohshima; Koshi Hashimoto; Masanobu Yamada; Hiroyuki Shimizu; Jeffrey Pessin; Masatomo Mori
Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytes.
Endocrinology 2008;149(1):40-9.
2007: Fumihiko Hakuno; Shigekazu Kurihara; Robert T Watson; Jeffrey Pessin; Shin-Ichiro Takahashi
53BP2S, interacting with insulin receptor substrates, modulates insulin signaling.
The Journal of biological chemistry 2007;282(52):37747-58.
2007: Encarnación Capilla; Naoko Suzuki; Jeffrey Pessin; June Chunqiu Hou
The glucose transporter 4 FQQI motif is necessary for Akt substrate of 160-kilodalton-dependent plasma membrane translocation but not Golgi-localized (gamma)-ear-containing Arf-binding protein-dependent entry into the insulin-responsive storage compartment.
Molecular endocrinology (Baltimore, Md.) 2007;21(12):3087-99.
2007: Le Min; Yuk M Leung; Alejandra Tomas; Robert T Watson; Herbert Y Gaisano; Philippe A Halban; Jeffrey Pessin; June Chunqiu Hou
Dynamin is functionally coupled to insulin granule exocytosis.
The Journal of biological chemistry 2007;282(46):33530-6.
2007: Clinton T Rubin; Encarnación Capilla; Y K Luu; Bhavin Busa; H Crawford; Daniel J Nolan; Vivek Mittal; C J Rosen; Jeffrey Pessin; Stefan Judex
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17879-84.
2007: Robert T Watson; Jeffrey Pessin
GLUT4 translocation: the last 200 nanometers.
Cellular signalling 2007;19(11):2209-17.
2007: June Chunqiu Hou; Jeffrey Pessin
Ins (endocytosis) and outs (exocytosis) of GLUT4 trafficking.
Current opinion in cell biology 2007;19(4):466-73.
2007: Claire Bastie; Haihong Zong; Jun Xu; Bhavin Busa; Stefan Judex; Irwin Kurland; Jeffrey Pessin
Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn.
Cell metabolism 2007;5(5):371-81.
2007: Irfan J Lodhi; Shian-Huey Chiang; Louise Chang; Daniel Vollenweider; Robert T Watson; Mayumi Inoue; Jeffrey Pessin; Alan Saltiel
Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.
Cell metabolism 2007;5(1):59-72.
2006: Dumaine Williams; Stuart W Hicks; Carolyn E Machamer; Jeffrey Pessin
Golgin-160 is required for the Golgi membrane sorting of the insulin-responsive glucose transporter GLUT4 in adipocytes.
Molecular biology of the cell 2006;17(12):5346-55.
2006: June Chunqiu Hou; Naoko Suzuki; Jeffrey Pessin; Robert T Watson
A specific dileucine motif is required for the GGA-dependent entry of newly synthesized insulin-responsive aminopeptidase into the insulin-responsive compartment.
The Journal of biological chemistry 2006;281(44):33457-66.
2006: Jérôme Vicogne; Daniel Vollenweider; Jeffery R Smith; Ping Huang; Michael A Frohman; Jeffrey Pessin
Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(40):14761-6.
2006: June Chunqiu Hou; Satoshi Shigematsu; Howard C Crawford; PZ Anastasiadis; Jeffrey Pessin
Dual regulation of Rho and Rac by p120 catenin controls adipocyte plasma membrane trafficking.
The Journal of biological chemistry 2006;281(33):23307-12.
2006: Alejandra Tomas; Barbara Yermen; Le Min; Jeffrey Pessin; Philippe A Halban
Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway.
Journal of cell science 2006;119(Pt 10):2156-67.
2006: Giuseppe Procino; Donne Bennett Caces; Giovanna Valenti; Jeffrey Pessin
Adipocytes support cAMP-dependent translocation of aquaporin-2 from intracellular sites distinct from the insulin-responsive GLUT4 storage compartment.
American journal of physiology. Renal physiology 2006;290(5):F985-94.
2006: Robert T Watson; Jeffrey Pessin
Bridging the GAP between insulin signaling and GLUT4 translocation.
Trends in biochemical sciences 2006;31(4):215-22.
2006: Linglin Xie; Daniel Boyle; Daniel Sanford; Philipp E Scherer; Jeffrey Pessin; Silvia Mora
Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles.
The Journal of biological chemistry 2006;281(11):7253-9.
2005: Gang Liu; June Chunqiu Hou; Robert T Watson; Jeffrey Pessin
Initial entry of IRAP into the insulin-responsive storage compartment occurs prior to basal or insulin-stimulated plasma membrane recycling.
American journal of physiology. Endocrinology and metabolism 2005;289(5):E746-52.
2005: Ping Huang; Yelena M Altshuller; June Chunqiu Hou; Jeffrey Pessin; Michael A Frohman
Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1.
Molecular biology of the cell 2005;16(6):2614-23.
2005: Jeffrey Pessin; Sherry A Marts
Sex, gender, drugs, and the brain.
Endocrinology 2005;146(4):1649.
2005: Eunjin Oh; Beth A Spurlin; Jeffrey Pessin; Debbie C Thurmond
Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance.
Diabetes 2005;54(3):638-47.
2004: Todd D Schraw; Garland L Crawford; Qiansheng Ren; Wangsun Choi; Debbie C Thurmond; Jeffrey Pessin; Sidney W Whiteheart
Platelets from Munc18c heterozygous mice exhibit normal stimulus-induced release.
Thrombosis and haemostasis 2004;92(4):829-37.
2004: Ahmir H Khan; Encarnación Capilla; June Chunqiu Hou; Robert T Watson; Jeffery R Smith; Jeffrey Pessin
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is dependent upon both the amino terminus and the large cytoplasmic loop.
The Journal of biological chemistry 2004;279(36):37505-11.
2004: Tsugumichi Saito; Shuichi Okada; Kihachi Ohshima; Eijiro Yamada; Minoru Sato; Yutaka Uehara; Hiroyuki Shimizu; Jeffrey Pessin; Masatomo Mori
Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF.
Endocrinology 2004;145(9):4232-43.
2004: Encarnación Capilla; Mònica Díaz; Amaya Albalat; Isabel Navarro; Jeffrey Pessin; Konrad Keller; Josep V Planas
Functional characterization of an insulin-responsive glucose transporter (GLUT4) from fish adipose tissue.
American journal of physiology. Endocrinology and metabolism 2004;287(2):E348-57.
2004: Makoto Kanzaki; Megumi Furukawa; William Raab; Jeffrey Pessin
Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling.
The Journal of biological chemistry 2004;279(29):30622-33.
2004: Robert T Watson; Ahmir H Khan; Megumi Furukawa; June Chunqiu Hou; Lin Li; Makoto Kanzaki; Shuichi Okada; Konstantin V Kandror; Jeffrey Pessin
Entry of newly synthesized GLUT4 into the insulin-responsive storage compartment is GGA dependent.
The EMBO journal 2004;23(10):2059-70.
2004: Robert T Watson; Makoto Kanzaki; Jeffrey Pessin
Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes.
Endocrine reviews 2004;25(2):177-204.
2004: Makoto Kanzaki; Silvia Mora; Joseph B Hwang; Alan Saltiel; Jeffrey Pessin
Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways.
The Journal of cell biology 2004;164(2):279-90.
2003: Alan Saltiel; Jeffrey Pessin
Insulin signaling in microdomains of the plasma membrane.
Traffic (Copenhagen, Denmark) 2003;4(11):711-6.
2003: Amanda H Wyman; Maggie M-Y Chi; Joan Riley; Mary O Carayannopoulos; Chunmei Yang; Kenneth Coker; Jeffrey Pessin; Kelle H Moley
Syntaxin 4 expression affects glucose transporter 8 translocation and embryo survival.
Molecular endocrinology (Baltimore, Md.) 2003;17(10):2096-102.
2003: Tsugumichi Saito; Shuichi Okada; Eijiro Yamada; Kihachi Ohshima; Hiroyuki Shimizu; Kenju Shimomura; Minoru Sato; Jeffrey Pessin; Masatomo Mori
Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell.
The Journal of biological chemistry 2003;278(38):36718-25.
2003: June Chunqiu Hou; Jeffrey Pessin
Lipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actin.
Molecular biology of the cell 2003;14(9):3578-91.
2003: Todd D Schraw; Tara W Rutledge; Garland L Crawford; Audrey M Bernstein; Amanda L Kalen; Jeffrey Pessin; Sidney W Whiteheart
Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release.
Blood 2003;102(5):1716-22.
2003: Makoto Kanzaki; Jeffrey Pessin
Insulin signaling: GLUT4 vesicles exit via the exocyst.
Current biology : CB 2003;13(14):R574-6.
2003: Sean M Crosson; Ahmir Khan; John Printen; Jeffrey Pessin; Alan Saltiel
PTG gene deletion causes impaired glycogen synthesis and developmental insulin resistance.
The Journal of clinical investigation 2003;111(9):1423-32.
2003: Debbie C Thurmond; Carmen Gonelle-Gispert; Megumi Furukawa; Philippe A Halban; Jeffrey Pessin
Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):732-42.
2003: Satoshi Shigematsu; Robert T Watson; Ahmir H Khan; Jeffrey Pessin
The adipocyte plasma membrane caveolin functional/structural organization is necessary for the efficient endocytosis of GLUT4.
The Journal of biological chemistry 2003;278(12):10683-90.
2003: Robert T Watson; Megumi Furukawa; Shian-Huey Chiang; Diana Boeglin; Makoto Kanzaki; Alan Saltiel; Jeffrey Pessin
The exocytotic trafficking of TC10 occurs through both classical and nonclassical secretory transport pathways in 3T3L1 adipocytes.
Molecular and cellular biology 2003;23(3):961-74.
2003: Kendall D Carey; Robert T Watson; Jeffrey Pessin; Philip J S Stork
The requirement of specific membrane domains for Raf-1 phosphorylation and activation.
The Journal of biological chemistry 2003;278(5):3185-96.
2003: Shuichi Okada; Masatomo Mori; Jeffrey Pessin
Introduction of DNA into 3T3-L1 adipocytes by electroporation.
Methods in molecular medicine 2003;83():93-6.
2002: Philippe Gual; Satoshi Shigematsu; Makoto Kanzaki; Thierry Grémeaux; Teresa Gonzalez; Jeffrey Pessin; Yannick Le Marchand-Brustel; Jean-François Tanti
A Crk-II/TC10 signaling pathway is required for osmotic shock-stimulated glucose transport.
The Journal of biological chemistry 2002;277(46):43980-6.
2002: Ahmir H Khan; Jeffrey Pessin
Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways.
Diabetologia 2002;45(11):1475-83.
2002: Silvia Mora; Jeffrey Pessin
An adipocentric view of signaling and intracellular trafficking.
Diabetes/metabolism research and reviews 2002;18(5):345-56.
2002: Akiko Kimura; Silvia Mora; Satoshi Shigematsu; Jeffrey Pessin; Alan Saltiel
The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1.
The Journal of biological chemistry 2002;277(33):30153-8.
2002: Silvia Mora; Paul L Durham; Jeffery R Smith; Andrew F Russo; Andreas Jeromin; Jeffrey Pessin
NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway.
The Journal of biological chemistry 2002;277(30):27494-500.
2002: Makoto Kanzaki; Jeffrey Pessin
Caveolin-associated filamentous actin (Cav-actin) defines a novel F-actin structure in adipocytes.
The Journal of biological chemistry 2002;277(29):25867-9.
2002: Makoto Kanzaki; Robert T Watson; June Chunqiu Hou; Mark Stamnes; Alan Saltiel; Jeffrey Pessin
Small GTP-binding protein TC10 differentially regulates two distinct populations of filamentous actin in 3T3L1 adipocytes.
Molecular biology of the cell 2002;13(7):2334-46.
2002: Lee-Ann H Allen; Chunmei Yang; Jeffrey Pessin
Rate and extent of phagocytosis in macrophages lacking vamp3.
Journal of leukocyte biology 2002;72(1):217-21.
2002: Satoshi Shigematsu; Ahmir H Khan; Makoto Kanzaki; Jeffrey Pessin
Intracellular insulin-responsive glucose transporter (GLUT4) distribution but not insulin-stimulated GLUT4 exocytosis and recycling are microtubule dependent.
Molecular endocrinology (Baltimore, Md.) 2002;16(5):1060-8.
2002: Shian-Huey Chiang; June Chunqiu Hou; Joseph Hwang; Jeffrey Pessin; Alan Saltiel
Cloning and functional characterization of related TC10 isoforms, a subfamily of Rho proteins involved in insulin-stimulated glucose transport.
The Journal of biological chemistry 2002;277(15):13067-73.
2002: Ognian C Ikonomov; Diego Sbrissa; Krzysztof Mlak; Makoto Kanzaki; Jeffrey Pessin; Assia Shisheva
Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.
The Journal of biological chemistry 2002;277(11):9206-11.
2002: Alan Saltiel; Jeffrey Pessin
Insulin signaling pathways in time and space.
Trends in cell biology 2002;12(2):65-71.
2001: Makoto Kanzaki; Robert T Watson; Ahmir H Khan; Jeffrey Pessin
Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes.
The Journal of biological chemistry 2001;276(52):49331-6.
2001: Robert T Watson; Jeffrey Pessin
Subcellular compartmentalization and trafficking of the insulin-responsive glucose transporter, GLUT4.
Experimental cell research 2001;271(1):75-83.
2001: Makoto Kanzaki; Jeffrey Pessin
Insulin-stimulated GLUT4 translocation in adipocytes is dependent upon cortical actin remodeling.
The Journal of biological chemistry 2001;276(45):42436-44.
2001: Debbie C Thurmond; Jeffrey Pessin
Molecular machinery involved in the insulin-regulated fusion of GLUT4-containing vesicles with the plasma membrane (review).
Molecular membrane biology 2001;18(4):237-45.
2001: Robert T Watson; Satoshi Shigematsu; Shian-Huey Chiang; Silvia Mora; Makoto Kanzaki; Ian G Macara; Alan Saltiel; Jeffrey Pessin
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation.
The Journal of cell biology 2001;154(4):829-40.
2001: Robert T Watson; Jeffrey Pessin
Transmembrane domain length determines intracellular membrane compartment localization of syntaxins 3, 4, and 5.
American journal of physiology. Cell physiology 2001;281(1):C215-23.
2001: Satoshi Shigematsu; S L Miller; Jeffrey Pessin
Differentiated 3T3L1 adipocytes are composed of heterogenous cell populations with distinct receptor tyrosine kinase signaling properties.
The Journal of biological chemistry 2001;276(18):15292-7.
2001: Chunmei Yang; Kenneth Coker; J K Kim; Silvia Mora; Debbie C Thurmond; A C Davis; Baoli Yang; R A Williamson; Gerald I Shulman; Jeffrey Pessin
Syntaxin 4 heterozygous knockout mice develop muscle insulin resistance.
The Journal of clinical investigation 2001;107(10):1311-8.
2001: Silvia Mora; Chunmei Yang; J W Ryder; Diana Boeglin; Jeffrey Pessin
The MEF2A and MEF2D isoforms are differentially regulated in muscle and adipose tissue during states of insulin deficiency.
Endocrinology 2001;142(5):1999-2004.
2001: Shian-Huey Chiang; Christian A Baumann; Makoto Kanzaki; D C Thurmond; Robert T Watson; CL Neudauer; Ian G Macara; Jeffrey Pessin; Alan Saltiel
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10.
Nature 2001;410(6831):944-8.
2001: Chunmei Yang; Silvia Mora; J W Ryder; Kenneth Coker; P Hansen; Lee-Ann H Allen; Jeffrey Pessin
VAMP3 null mice display normal constitutive, insulin- and exercise-regulated vesicle trafficking.
Molecular and cellular biology 2001;21(5):1573-80.
2001: Ahmir H Khan; Debbie C Thurmond; Chunmei Yang; Brian P Ceresa; Curt D Sigmund; Jeffrey Pessin
Munc18c regulates insulin-stimulated glut4 translocation to the transverse tubules in skeletal muscle.
The Journal of biological chemistry 2001;276(6):4063-9.
2001: Makoto Kanzaki; Jeffrey Pessin
Signal integration and the specificity of insulin action.
Cell biochemistry and biophysics 2001;35(2):191-209.
2001: Robert T Watson; Jeffrey Pessin
Intracellular organization of insulin signaling and GLUT4 translocation.
Recent progress in hormone research 2001;56():175-93.
2000: Christian A Baumann; V Ribon; Makoto Kanzaki; D C Thurmond; S Mora; S Shigematsu; P E Bickel; Jeffrey Pessin; Alan Saltiel
CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Nature 2000;407(6801):202-7.
2000: Debbie C Thurmond; Jeffrey Pessin
Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant.
The EMBO journal 2000;19(14):3565-75.
2000: Jeffrey Pessin; Alan Saltiel
Signaling pathways in insulin action: molecular targets of insulin resistance.
The Journal of clinical investigation 2000;106(2):165-9.
2000: Silvia Mora; Jeffrey Pessin
The MEF2A isoform is required for striated muscle-specific expression of the insulin-responsive GLUT4 glucose transporter.
The Journal of biological chemistry 2000;275(21):16323-8.
2000: AW Kao; Chunmei Yang; Jeffrey Pessin
Functional comparison of the role of dynamin 2 splice variants on GLUT-4 endocytosis in 3T3L1 adipocytes.
American journal of physiology. Endocrinology and metabolism 2000;278(5):E825-31.
2000: Makoto Kanzaki; Robert T Watson; Nikolai O Artemyev; Jeffrey Pessin
The trimeric GTP-binding protein (G(q)/G(11)) alpha subunit is required for insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes.
The Journal of biological chemistry 2000;275(10):7167-75.
2000: Chunmei Yang; Robert T Watson; Jeffrey S Elmendorf; D B Sacks; Jeffrey Pessin
Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) 2000;14(2):317-26.
2000: Robert T Watson; Jeffrey Pessin
Functional cooperation of two independent targeting domains in syntaxin 6 is required for its efficient localization in the trans-golgi network of 3T3L1 adipocytes.
The Journal of biological chemistry 2000;275(2):1261-8.
2000: Debbie C Thurmond; Makoto Kanzaki; Ahmir H Khan; Jeffrey Pessin
Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesicles.
Molecular and cellular biology 2000;20(1):379-88.
1999: Jeffrey S Elmendorf; Diana Boeglin; Jeffrey Pessin
Temporal separation of insulin-stimulated GLUT4/IRAP vesicle plasma membrane docking and fusion in 3T3L1 adipocytes.
The Journal of biological chemistry 1999;274(52):37357-61.
1999: Dongsheng Duan; Q Li; AW Kao; Y Yue; Jeffrey Pessin; John F Engelhardt
Dynamin is required for recombinant adeno-associated virus type 2 infection.
Journal of virology 1999;73(12):10371-6.
1999: Jeffrey S Elmendorf; Jeffrey Pessin
Insulin signaling regulating the trafficking and plasma membrane fusion of GLUT4-containing intracellular vesicles.
Experimental cell research 1999;253(1):55-62.
1999: Desheng Chen; Raymond V Fucini; Ann Louise Olson; B A Hemmings; Jeffrey Pessin
Osmotic shock inhibits insulin signaling by maintaining Akt/protein kinase B in an inactive dephosphorylated state.
Molecular and cellular biology 1999;19(7):4684-94.
1999: Raymond V Fucini; S Okada; Jeffrey Pessin
Insulin-induced desensitization of extracellular signal-regulated kinase activation results from an inhibition of Raf activity independent of Ras activation and dissociation of the Grb2-SOS complex.
The Journal of biological chemistry 1999;274(26):18651-8.
1999: SA Summers; A W Kao; AD Kohn; G S Backus; Richard A Roth; Jeffrey Pessin; Morris J Birnbaum
The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism.
The Journal of biological chemistry 1999;274(25):17934-40.
1999: AW Kao; Y Noda; J H Johnson; Jeffrey Pessin; Alan Saltiel
Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4.
The Journal of biological chemistry 1999;274(25):17742-7.
1999: J Min; S Okada; M Kanzaki; Jeffrey S Elmendorf; Kenneth Coker; Brian P Ceresa; Li-Jyun Syu; Y Noda; Alan Saltiel; Jeffrey Pessin
Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes.
Molecular cell 1999;3(6):751-60.
1999: Jeffrey Pessin; S Okada
Insulin and EGF receptors integrate the Ras and Rap signaling pathways.
Endocrine journal 1999;46 Suppl():S11-6.
1999: Jeffrey Pessin; Debbie C Thurmond; Jeffrey S Elmendorf; Kenneth Coker; S Okada
Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!
The Journal of biological chemistry 1999;274(5):2593-6.
1998: Debbie C Thurmond; Brian P Ceresa; S Okada; Jeffrey S Elmendorf; Kenneth Coker; Jeffrey Pessin
Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytes.
The Journal of biological chemistry 1998;273(50):33876-83.
1998: D K Short; S Okada; K Yamauchi; Jeffrey Pessin
Adenovirus-mediated transfer of a modified human proinsulin gene reverses hyperglycemia in diabetic mice.
The American journal of physiology 1998;275(5 Pt 1):E748-56.
1998: AW Kao; Brian P Ceresa; S R Santeler; Jeffrey Pessin
Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling.
The Journal of biological chemistry 1998;273(39):25450-7.
1998: Brian P Ceresa; AW Kao; S R Santeler; Jeffrey Pessin
Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways.
Molecular and cellular biology 1998;18(7):3862-70.
1998: M V Thai; Suresh Guruswamy; KT Cao; Jeffrey Pessin; Ann Louise Olson
Myocyte enhancer factor 2 (MEF2)-binding site is required for GLUT4 gene expression in transgenic mice. Regulation of MEF2 DNA binding activity in insulin-deficient diabetes.
The Journal of biological chemistry 1998;273(23):14285-92.
1998: Jeffrey S Elmendorf; Desheng Chen; Jeffrey Pessin
Guanosine 5'-O-(3-thiotriphosphate) (GTPgammaS) stimulation of GLUT4 translocation is tyrosine kinase-dependent.
The Journal of biological chemistry 1998;273(21):13289-96.
1998: H Zhao; S Okada; Jeffrey Pessin; Gary A Koretzky
Insulin receptor-mediated dissociation of Grb2 from Sos involves phosphorylation of Sos by kinase(s) other than extracellular signal-regulated kinase.
The Journal of biological chemistry 1998;273(20):12061-7.
1998: Brian P Ceresa; Jeffrey Pessin
Insulin regulation of the Ras activation/inactivation cycle.
Molecular and cellular biochemistry 1998;182(1-2):23-9.
1998: JP Jones; Edward B Tapscott; Ann Louise Olson; Jeffrey Pessin; G Lynis Dohm
Regulation of glucose transporters GLUT-4 and GLUT-1 gene transcription in denervated skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;84(5):1661-6.
1998: S Okada; M Matsuda; M Anafi; T Pawson; Jeffrey Pessin
Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.
The EMBO journal 1998;17(9):2554-65.
1997: S Okada; Jeffrey Pessin
Insulin and epidermal growth factor stimulate a conformational change in Rap1 and dissociation of the CrkII-C3G complex.
The Journal of biological chemistry 1997;272(45):28179-82.
1997: S Okada; AW Kao; Brian P Ceresa; PA Blaikie; Benjamin L Margolis; Jeffrey Pessin
The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway.
The Journal of biological chemistry 1997;272(44):28042-9.
1997: Desheng Chen; Jeffrey S Elmendorf; Ann Louise Olson; X Li; Henry Earp; Jeffrey Pessin
Osmotic shock stimulates GLUT4 translocation in 3T3L1 adipocytes by a novel tyrosine kinase pathway.
The Journal of biological chemistry 1997;272(43):27401-10.
1997: J A Vanderkuur; Elizabeth R Butch; S B Waters; Jeffrey Pessin; Kun-Liang Guan; Christin Carter-Su
Signaling molecules involved in coupling growth hormone receptor to mitogen-activated protein kinase activation.
Endocrinology 1997;138(10):4301-7.
1997: Brian P Ceresa; Curt M Horvath; Jeffrey Pessin
Signal transducer and activator of transcription-3 serine phosphorylation by insulin is mediated by a Ras/Raf/MEK-dependent pathway.
Endocrinology 1997;138(10):4131-7.
1997: H Zhao; Y Y Li; Raymond V Fucini; SE Ross; Jeffrey Pessin; Gary A Koretzky
T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.
The Journal of biological chemistry 1997;272(34):21625-34.
1997: AW Kao; S B Waters; S Okada; Jeffrey Pessin
Insulin stimulates the phosphorylation of the 66- and 52-kilodalton Shc isoforms by distinct pathways.
Endocrinology 1997;138(6):2474-80.
1997: Ann Louise Olson; John B Knight; Jeffrey Pessin
Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes.
Molecular and cellular biology 1997;17(5):2425-35.
1997: C J Torrance; stephen usala; Jeffrey Pessin; G Lynis Dohm
Characterization of a low affinity thyroid hormone receptor binding site within the rat GLUT4 gene promoter.
Endocrinology 1997;138(3):1215-23.
1996: S Okada; Jeffrey Pessin
Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor.
The Journal of biological chemistry 1996;271(41):25533-8.
1996: Y Y Li; M Baccam; S B Waters; Jeffrey Pessin; Gail A Bishop; Gary A Koretzky
CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1440-7.
1996: S B Waters; Desheng Chen; AW Kao; S Okada; KH Holt; Jeffrey Pessin
Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation.
The Journal of biological chemistry 1996;271(30):18224-30.
1996: Brian P Ceresa; Jeffrey Pessin
Insulin stimulates the serine phosphorylation of the signal transducer and activator of transcription (STAT3) isoform.
The Journal of biological chemistry 1996;271(21):12121-4.
1996: KH Holt; S B Waters; S Okada; K Yamauchi; S J Decker; Alan Saltiel; David G Motto; Gary A Koretzky; Jeffrey Pessin
Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex.
The Journal of biological chemistry 1996;271(14):8300-6.
1996: S B Waters; KH Holt; Jeffrey Pessin
SOS phosphorylation and disassociation of the Grb2-SOS complex by the ERK and JNK signaling pathways.
The Journal of biological chemistry 1996;271(11):6328-32.
1996: Sophie Tartare-Deckert; J Murdaca; Dominique Sawka-Verhelle; K H Holt; Jeffrey Pessin; Emmanuel Van Obberghen
Interaction of the molecular weight 85K regulatory subunit of the phosphatidylinositol 3-kinase with the insulin receptor and the insulin-like growth factor-1 (IGF- I) receptor: comparative study using the yeast two-hybrid system.
Endocrinology 1996;137(3):1019-24.
1996: KH Holt; B G Kasson; Jeffrey Pessin
Insulin stimulation of a MEK-dependent but ERK-independent SOS protein kinase.
Molecular and cellular biology 1996;16(2):577-83.
1996: S B Waters; Jeffrey Pessin
Insulin receptor substrate 1 and 2 (IRS1 and IRS2): what a tangled web we weave.
Trends in cell biology 1996;6(1):1-4.
1996: Ann Louise Olson; Jeffrey Pessin
Structure, function, and regulation of the mammalian facilitative glucose transporter gene family.
Annual review of nutrition 1996;16():235-56.
1995: Ann Louise Olson; Jeffrey Pessin
Transcriptional regulation of the human GLUT4 gene promoter in diabetic transgenic mice.
The Journal of biological chemistry 1995;270(40):23491-5.
1995: S B Waters; KH Holt; S E Ross; Li-Jyun Syu; K L Guan; Alan Saltiel; Gary A Koretzky; Jeffrey Pessin
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
The Journal of biological chemistry 1995;270(36):20883-6.
1995: D F Lazar; R J Wiese; MJ Brady; CC Mastick; S B Waters; K Yamauchi; Jeffrey Pessin; P Cuatrecasas; Alan Saltiel
Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin.
The Journal of biological chemistry 1995;270(35):20801-7.
1995: S Okada; K Yamauchi; Jeffrey Pessin
Shc isoform-specific tyrosine phosphorylation by the insulin and epidermal growth factor receptors.
The Journal of biological chemistry 1995;270(35):20737-41.
1995: K Yamauchi; V Ribon; Alan Saltiel; Jeffrey Pessin
Identification of the major SHPTP2-binding protein that is tyrosine-phosphorylated in response to insulin.
The Journal of biological chemistry 1995;270(30):17716-22.
1995: K Yamauchi; Jeffrey Pessin
Epidermal growth factor-induced association of the SHPTP2 protein tyrosine phosphatase with a 115-kDa phosphotyrosine protein.
The Journal of biological chemistry 1995;270(25):14871-4.
1995: S B Waters; K Yamauchi; Jeffrey Pessin
Insulin-stimulated disassociation of the SOS-Grb2 complex.
Molecular and cellular biology 1995;15(5):2791-9.
1995: Ann Louise Olson; N P Edgington; W Scott Moye-Rowley; Jeffrey Pessin
Characterization of 5'-heterogeneity of the rat GLUT4/muscle-adipose glucose transporter gene product.
Endocrinology 1995;136(5):1962-8.
1995: J B Knight; K Yamauchi; Jeffrey Pessin
Divergent insulin and platelet-derived growth factor regulation of focal adhesion kinase (pp125FAK) tyrosine phosphorylation, and rearrangement of actin stress fibers.
The Journal of biological chemistry 1995;270(17):10199-203.
1995: E Michael Gibbs; Jeffrey L Stock; S C McCoid; H A Stukenbrok; Jeffrey Pessin; Ralph W Stevenson; Anthony J Milici; John McNeish
Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).
The Journal of clinical investigation 1995;95(4):1512-8.
1995: K Yamauchi; K L Milarski; Alan Saltiel; Jeffrey Pessin
Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):664-8.
1995: Polly A Hansen; Eric Gulve; BA Marshall; J Gao; Jeffrey Pessin; John O Holloszy; Mike Mueckler
Skeletal muscle glucose transport and metabolism are enhanced in transgenic mice overexpressing the Glut4 glucose transporter.
The Journal of biological chemistry 1995;270(4):1679-84.
1994: K Yamauchi; Jeffrey Pessin
Insulin receptor substrate-1 (IRS1) and Shc compete for a limited pool of Grb2 in mediating insulin downstream signaling.
The Journal of biological chemistry 1994;269(49):31107-14.
1994: Judith L Treadway; D M Hargrove; N A Nardone; R Kirk McPherson; J F Russo; Anthony J Milici; H A Stukenbrok; E Michael Gibbs; Ralph W Stevenson; Jeffrey Pessin
Enhanced peripheral glucose utilization in transgenic mice expressing the human GLUT4 gene.
The Journal of biological chemistry 1994;269(47):29956-61.
1994: M L Liu; Ann Louise Olson; N P Edgington; W Scott Moye-Rowley; Jeffrey Pessin
Myocyte enhancer factor 2 (MEF2) binding site is essential for C2C12 myotube-specific expression of the rat GLUT4/muscle-adipose facilitative glucose transporter gene.
The Journal of biological chemistry 1994;269(45):28514-21.
1994: K Yamauchi; Jeffrey Pessin
Enhancement or inhibition of insulin signaling by insulin receptor substrate 1 is cell context dependent.
Molecular and cellular biology 1994;14(7):4427-34.
1994: Ann Louise Olson; Jeffrey Pessin
Regulation of c-fos expression in adipose and muscle tissue of diabetic rats.
Endocrinology 1994;134(1):271-6.
1994: KH Holt; L Olson; W Scott Moye-Rowley; Jeffrey Pessin
Phosphatidylinositol 3-kinase activation is mediated by high-affinity interactions between distinct domains within the p110 and p85 subunits.
Molecular and cellular biology 1994;14(1):42-9.
1993: M L Liu; E Michael Gibbs; S C McCoid; Anthony J Milici; H A Stukenbrok; R Kirk McPherson; Judith L Treadway; Jeffrey Pessin
Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11346-50.
1993: S B Waters; K Yamauchi; Jeffrey Pessin
Functional expression of insulin receptor substrate-1 is required for insulin-stimulated mitogenic signaling.
The Journal of biological chemistry 1993;268(30):22231-4.
1993: J M Richardson; Jeffrey Pessin
Identification of a skeletal muscle-specific regulatory domain in the rat GLUT4/muscle-fat gene.
The Journal of biological chemistry 1993;268(28):21021-7.
1993: Jeffrey Pessin; A L Frattali
Molecular dynamics of insulin/IGF-I receptor transmembrane signaling.
Molecular reproduction and development 1993;35(4):339-44; discussion 344-5.
1993: K Yamauchi; KH Holt; Jeffrey Pessin
Phosphatidylinositol 3-kinase functions upstream of Ras and Raf in mediating insulin stimulation of c-fos transcription.
The Journal of biological chemistry 1993;268(20):14597-600.
1993: A L Frattali; Jeffrey Pessin
Molecular defects of insulin/IGF-1 receptor transmembrane signaling.
Annals of the New York Academy of Sciences 1993;687():77-89.
1993: Ann Louise Olson; M L Liu; W Scott Moye-Rowley; John B Buse; Graeme I Bell; Jeffrey Pessin
Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
The Journal of biological chemistry 1993;268(13):9839-46.
1993: A L Frattali; Jeffrey Pessin
Relationship between alpha subunit ligand occupancy and beta subunit autophosphorylation in insulin/insulin-like growth factor-1 hybrid receptors.
The Journal of biological chemistry 1993;268(10):7393-400.
1993: P M Gerrits; Ann Louise Olson; Jeffrey Pessin
Regulation of the GLUT4/muscle-fat glucose transporter mRNA in adipose tissue of insulin-deficient diabetic rats.
The Journal of biological chemistry 1993;268(1):640-4.
1993: Jeffrey Pessin
Molecular properties of insulin/IGF-1 hybrid receptors. 4th International Symposium on Insulin, IGFs and their Receptors.
Advances in experimental medicine and biology 1993;343():133-44.
1992: Judith L Treadway; A L Frattali; Jeffrey Pessin
Intramolecular subunit interactions between insulin and insulin-like growth factor 1 alpha beta half-receptors induced by ligand and Mn/MgATP binding.
Biochemistry 1992;31(47):11801-5.
1992: William I Sivitz; S L DeSautel; E C Lee; Jeffrey Pessin
Time-dependent regulation of rat adipose tissue glucose transporter (GLUT4) mRNA and protein by insulin in streptozocin-diabetic and normal rats.
Metabolism: clinical and experimental 1992;41(11):1267-72.
1992: John B Buse; K Yasuda; T P Lay; T S Seo; Ann Louise Olson; Jeffrey Pessin; J H Karam; S Seino; Graeme I Bell
Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
Diabetes 1992;41(11):1436-45.
1992: A L Frattali; Judith L Treadway; Jeffrey Pessin
Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation.
The Journal of biological chemistry 1992;267(27):19521-8.
1992: André Marette; J M Richardson; T Ramlal; T W Balon; Mladen Vranic; Jeffrey Pessin; Amira Klip
Abundance, localization, and insulin-induced translocation of glucose transporters in red and white muscle.
The American journal of physiology 1992;263(2 Pt 1):C443-52.
1992: M L Liu; Ann Louise Olson; W Scott Moye-Rowley; John B Buse; Graeme I Bell; Jeffrey Pessin
Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
The Journal of biological chemistry 1992;267(17):11673-6.
1992: Jeffrey Pessin; Graeme I Bell
Mammalian facilitative glucose transporter family: structure and molecular regulation.
Annual review of physiology 1992;54():911-30.
1992: A L Frattali; Judith L Treadway; Jeffrey Pessin
Insulin/IGF-1 hybrid receptors: implications for the dominant-negative phenotype in syndromes of insulin resistance.
Journal of cellular biochemistry 1992;48(1):43-50.
1991: G I Bell; H Fukumoto; Charles F Burant; S Seino; William I Sivitz; Jeffrey Pessin
Facilitative glucose transport proteins: structure and regulation of expression in adipose tissue.
International journal of obesity 1991;15 Suppl 2():127-32.
1991: J M Richardson; T W Balon; Judith L Treadway; Jeffrey Pessin
Differential regulation of glucose transporter activity and expression in red and white skeletal muscle.
The Journal of biological chemistry 1991;266(19):12690-4.
1991: A L Frattali; Judith L Treadway; Jeffrey Pessin
Evidence supporting a passive role for the insulin receptor transmembrane domain in insulin-dependent signal transduction.
The Journal of biological chemistry 1991;266(15):9829-34.
1991: Judith L Treadway; B D Morrison; M A Soos; K Siddle; J Olefsky; A Ullrich; D A McClain; Jeffrey Pessin
Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(1):214-8.
1991: Jeffrey Pessin; J M Richardson; William I Sivitz
Regulation of the glucose transporter in animal models of diabetes.
Advances in experimental medicine and biology 1991;293():249-62.
1991: Charles F Burant; William I Sivitz; H Fukumoto; T Kayano; S Nagamatsu; S Seino; Jeffrey Pessin; Graeme I Bell
Mammalian glucose transporters: structure and molecular regulation.
Recent progress in hormone research 1991;47():349-87; discussion 387-8.
1990: Judith L Treadway; B D Morrison; John A Wemmie; I Frias; Thomas O'Hare; P F Pilch; Jeffrey Pessin
The endogenous functional turkey erythrocyte and rat liver insulin receptor is an alpha 2 beta 2 heterotetrameric complex.
The Biochemical journal 1990;271(1):99-105.
1990: William I Sivitz; S L DeSautel; T Kayano; Graeme I Bell; Jeffrey Pessin
Regulation of glucose transporter messenger RNA levels in rat adipose tissue by insulin.
Molecular endocrinology (Baltimore, Md.) 1990;4(4):583-8.
1990: P S Walker; T Ramlal; V Sarabia; U M Koivisto; Philip J Bilan; Jeffrey Pessin; Amira Klip
Glucose transport activity in L6 muscle cells is regulated by the coordinate control of subcellular glucose transporter distribution, biosynthesis, and mRNA transcription.
The Journal of biological chemistry 1990;265(3):1516-23.
1989: Judith L Treadway; B D Morrison; Ira D Goldfine; Jeffrey Pessin
Assembly of insulin/insulin-like growth factor-1 hybrid receptors in vitro.
The Journal of biological chemistry 1989;264(36):21450-3.
1989: P A Wilden; Judith L Treadway; B D Morrison; Jeffrey Pessin
IGF-1-dependent subunit communication of the IGF-1 holoreceptor: interactions between alpha beta heterodimeric receptor halves.
Biochemistry 1989;28(25):9734-40.
1989: Judith L Treadway; J Whittaker; Jeffrey Pessin
Regulation of the insulin receptor kinase by hyperinsulinism.
The Journal of biological chemistry 1989;264(25):15136-43.
1989: William I Sivitz; S L DeSautel; T Kayano; Graeme I Bell; Jeffrey Pessin
Regulation of glucose transporter messenger RNA in insulin-deficient states.
Nature 1989;340(6228):72-4.
1989: B D Morrison; S M Feltz; Jeffrey Pessin
Polylysine specifically activates the insulin-dependent insulin receptor protein kinase.
The Journal of biological chemistry 1989;264(17):9994-10001.
1989: M L Swanson; Jeffrey Pessin
High affinity insulin binding in the human placenta insulin receptor requires alpha beta heterodimeric subunit interactions.
The Journal of membrane biology 1989;108(3):217-25.
1989: P S Walker; T Ramlal; J A Donovan; T P Doering; A Sandra; Amira Klip; Jeffrey Pessin
Insulin and glucose-dependent regulation of the glucose transport system in the rat L6 skeletal muscle cell line.
The Journal of biological chemistry 1989;264(11):6587-95.
1989: William I Sivitz; S DeSautel; P S Walker; Jeffrey Pessin
Regulation of the glucose transporter in developing rat brain.
Endocrinology 1989;124(4):1875-80.
1989: P A Wilden; B D Morrison; Jeffrey Pessin
Wheat germ agglutinin stimulation of alpha beta heterodimeric insulin receptor beta-subunit autophosphorylation by noncovalent association into an alpha 2 beta 2 heterotetrameric state.
Endocrinology 1989;124(2):971-9.
1989: P A Wilden; B D Morrison; Jeffrey Pessin
Relationship between insulin receptor subunit association and protein kinase activation: insulin-dependent covalent and Mn/MgATP-dependent noncovalent association of alpha beta heterodimeric insulin receptors into an alpha 2 beta 2 heterotetrameric state.
Biochemistry 1989;28(2):785-92.
1988: P S Walker; J A Donovan; Brian Van Ness; R E Fellows; Jeffrey Pessin
Glucose-dependent regulation of glucose transport activity, protein, and mRNA in primary cultures of rat brain glial cells.
The Journal of biological chemistry 1988;263(30):15594-601.
1988: M L Swanson; R K Keast; Michael L Jennings; Jeffrey Pessin
Heterogeneity in the human erythrocyte band 3 anion-transporter revealed by Triton X-114 phase partitioning.
The Biochemical journal 1988;255(1):229-34.
1988: B D Morrison; M L Swanson; L J Sweet; Jeffrey Pessin
Insulin-dependent covalent reassociation of isolated alpha beta heterodimeric insulin receptors into an alpha 2 beta 2 heterotetrameric disulfide-linked complex.
The Journal of biological chemistry 1988;263(16):7806-13.
1988: C Hofmann; R Thys; L J Sweet; A A Spector; Jeffrey Pessin
Transfer of functional insulin receptors to receptor-deficient target cells.
Endocrinology 1988;122(6):2865-72.
1988: S M Feltz; M L Swanson; John A Wemmie; Jeffrey Pessin
Functional properties of an isolated alpha beta heterodimeric human placenta insulin-like growth factor 1 receptor complex.
Biochemistry 1988;27(9):3234-42.
1988: M L Swanson; D T Dudley; P S Walker; T R Boyle; Jeffrey Pessin
Functional differences in insulin receptors in rat adipocyte and human placenta membranes.
Endocrinology 1988;122(3):967-75.
1987: L J Sweet; B D Morrison; P A Wilden; Jeffrey Pessin
Insulin-dependent intermolecular subunit communication between isolated alpha beta heterodimeric insulin receptor complexes.
The Journal of biological chemistry 1987;262(34):16730-8.
1987: P A Wilden; Jeffrey Pessin
Differential sensitivity of the insulin-receptor kinase to thiol and oxidizing agents in the absence and presence of insulin.
The Biochemical journal 1987;245(2):325-31.
1987: L J Sweet; D T Dudley; Jeffrey Pessin; A A Spector
Phospholipid activation of the insulin receptor kinase: regulation by phosphatidylinositol.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1987;1(1):55-9.
1987: L J Sweet; B D Morrison; Jeffrey Pessin
Isolation of functional alpha beta heterodimers from the purified human placental alpha 2 beta 2 heterotetrameric insulin receptor complex. A structural basis for insulin binding heterogeneity.
The Journal of biological chemistry 1987;262(15):6939-42.
1987: B D Morrison; Jeffrey Pessin
Insulin stimulation of the insulin receptor kinase can occur in the complete absence of beta subunit autophosphorylation.
The Journal of biological chemistry 1987;262(6):2861-8.
1986: L J Sweet; P A Wilden; Jeffrey Pessin
Dithiothreitol activation of the insulin receptor/kinase does not involve subunit dissociation of the native alpha 2 beta 2 insulin receptor subunit complex.
Biochemistry 1986;25(22):7068-74.
1986: P A Wilden; T R Boyle; M L Swanson; L J Sweet; Jeffrey Pessin
Alteration of intramolecular disulfides in insulin receptor/kinase by insulin and dithiothreitol: insulin potentiates the apparent dithiothreitol-dependent subunit reduction of insulin receptor.
Biochemistry 1986;25(15):4381-8.
1985: L J Sweet; P A Wilden; A A Spector; Jeffrey Pessin
Incorporation of the purified human placental insulin receptor into phospholipid vesicles.
Biochemistry 1985;24(23):6571-80.
1985: K T Yu; Jeffrey Pessin; M P Czech
Regulation of insulin receptor kinase by multisite phosphorylation.
Biochimie 1985;67(10-11):1081-93.
1985: T R Boyle; J Campana; L J Sweet; Jeffrey Pessin
Subunit structure of the purified human placental insulin receptor. Intramolecular subunit dissociation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
The Journal of biological chemistry 1985;260(14):8593-600.
1984: D J Kelleher; Jeffrey Pessin; Arnold E Ruoho; Gary L Johnson
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4316-20.
1984: Jeffrey Pessin; L G Tillotson; K J Isselbacher; M P Czech
Photoaffinity labeling of the stereospecific D-glucose transport system with cytochalasin B.
Federation proceedings 1984;43(8):2258-61.
1983: F J Chlapowski; B K Bertrand; Jeffrey Pessin; Y Oka; M P Czech
The relationship of microvesicles to the plasmalemma of rat adipocytes.
European journal of cell biology 1983;32(1):24-30.
1983: Jeffrey Pessin; W Gitomer; Y Oka; C L Oppenheimer; M P Czech
beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes.
The Journal of biological chemistry 1983;258(12):7386-94.
1983: C L Oppenheimer; Jeffrey Pessin; J Massague; W Gitomer; M P Czech
Insulin action rapidly modulates the apparent affinity of the insulin-like growth factor II receptor.
The Journal of biological chemistry 1983;258(8):4824-30.
1982: Christin Carter-Su; Jeffrey Pessin; R Mora; W Gitomer; M P Czech
Photoaffinity labeling of the human erythrocyte D-glucose transporter.
The Journal of biological chemistry 1982;257(10):5419-25.
1982: Jeffrey Pessin; L G Tillotson; K Yamada; W Gitomer; Christin Carter-Su; R Mora; K J Isselbacher; M P Czech
Identification of the stereospecific hexose transporter from starved and fed chicken embryo fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(7):2286-90.
1982: G M Omann; J Cimino; Jeffrey Pessin; M Glaser
Formation of the envelope of rous sarcoma virus and vesicular stomatitis virus from localized lipid regions in the plasma membrane.
Biophysical journal 1982;37(1):135-6.
1980: Jeffrey Pessin; M Glaser
Budding of Rous sarcoma virus and vesicular stomatitis virus from localized lipid regions in the plasma membrane of chicken embryo fibroblasts.
The Journal of biological chemistry 1980;255(19):9044-50.
1980: S Gidwitz; Jeffrey Pessin; M J Weber; M Glaser; D R Storm
Effect of membrane phospholipid composition changes on adenylate cyclase activity in normal and rous-sarcoma-transformed chicken embryo fibroblasts.
Biochimica et biophysica acta 1980;628(3):263-76.
1978: Jeffrey Pessin; D W Salter; M Glaser
Use of a fluorescent probe to compare the plasma membrane properties in normal and transformed cells. Evaluation of the interference by triacylglycerols and alkyldiacylglycerols.
Biochemistry 1978;17(10):1997-2004.
1977: A H Hale; Jeffrey Pessin; F Palmer; M J Weber; M Glaser
Modification of the lipid composition of normal and Rous sarcoma virus-infected cells. Effects on transformation-associated membrane properties.
The Journal of biological chemistry 1977;252(17):6190-200.