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Irina Caminschi

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Dominique Gatto; Gunasegaran Karupiah; Danielle Murphy-Durland; Peter Schofield; Katherine Wood; Irina Caminschi; Daniel Christ; Robert Brink
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells.
Jessica M Moffat; Elodie Segura; Jose A Villadangos; Paul U Cameron; Irina Caminschi; Gabriela Khoury; Sharon R Lewin; Justine D Mintern
Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation.
Ya Wang; Yiping Wang; Yuan Min Wang; Debbie Watson; Huiling Wu; Geoff Yu Zhang; Dong Zheng; Guoping Zheng; Jimmy Jianheng Zhou; Irina Caminschi; Qi Cao; David C Harris; Min Hu; Mireille H Lahoud; Thian Kui Tan; ChangQi Wang; Stephen I Alexander
DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats.

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All Publications

2013: Dominique Gatto; Gunasegaran Karupiah; Danielle Murphy-Durland; Peter Schofield; Katherine Wood; Irina Caminschi; Daniel Christ; Robert Brink
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells.
Nature immunology 2013;14(5):446-53.
2013: Jessica M Moffat; Elodie Segura; Jose A Villadangos; Paul U Cameron; Irina Caminschi; Gabriela Khoury; Sharon R Lewin; Justine D Mintern
Targeting antigen to bone marrow stromal cell-2 expressed by conventional and plasmacytoid dendritic cells elicits efficient antigen presentation.
European journal of immunology 2013;43(3):595-605.
2013: Ya Wang; Yiping Wang; Yuan Min Wang; Debbie Watson; Huiling Wu; Geoff Yu Zhang; Dong Zheng; Guoping Zheng; Jimmy Jianheng Zhou; Irina Caminschi; Qi Cao; David C Harris; Min Hu; Mireille H Lahoud; Thian Kui Tan; ChangQi Wang; Stephen I Alexander
DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats.
Kidney international 2013;83(2):223-32.
2012: Mireille Lahoud; Chin-Nien Lee; Simone Meuter; Justine D Mintern; Nicos A Nicola; Michel C Nussenzweig; Meredith O'Keeffe; Antonia N Policheni; Jamie Rossjohn; Ken Shortman; Katryn J Stacey; Lucy C Sullivan; Javier Vega-Ramos; Jose A Villadangos; Jian-Guo Zhang; Fatma Ahmet; Richard Berry; Andrew G Brooks; William R Heath; Susie Kitsoulis; Irina Caminschi
DEC-205 is a cell surface receptor for CpG oligonucleotides.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(40):16270-5.
2012: Jian-Guo Zhang; Soo San Wan; Jake Baum; Rajini Brammananth; Irina Caminschi; Wei Jin Chin; Peter M Colman; Ross L Coppel; Peter Czabotar; David C S Huang; Emma C Josefsson; Benjamin T Kile; Susie Kitsoulis; Jinhua Lu; Justine D Mintern; Narla Mohandas; Nicos A Nicola; Maya A Olshina; Lorraine A O'Reilly; Antonia N Policheni; Adeline Y Robin; Ken Shortman; Kirsteen M Tullett; Mark F Van Delft; Wilson Wong; Mark D Wright; Mireille Lahoud
The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.
Immunity 2012;36(4):646-57.
2012: Irina Caminschi; William R Heath; Mireille Lahoud; Kenneth M Murphy; Jose A Villadangos; David Vremec; eta ahmet; Ken Shortman
Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3(-/-) mice.
Molecular immunology 2012;50(1-2):9-17.
2012: Irina Caminschi; Ken Shortman
Boosting antibody responses by targeting antigens to dendritic cells.
Trends in immunology 2012;33(2):71-7.
2012: Irina Caminschi; Eugene Maraskovsky; William Ross Heath
Targeting Dendritic Cells in vivo for Cancer Therapy.
Frontiers in immunology 2012;3():13.
2011: A Nicole Desch; Emmanuel L Gautier; Peter M Henson; Ross M Kedl; Mireille Lahoud; Kenneth Murphy; Gwendalyn J Randolph; Ken Shortman; Irina Caminschi; Claudia V Jakubzick
CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen.
The Journal of experimental medicine 2011;208(9):1789-97.
2011: Mireille Lahoud; Chin-Nien Lee; Andrew M Lew; Scott N Mueller; Belinda Phipson; Wei Shi; Ken Shortman; Gordon K Smyth; David Vremec; Soo San Wan; Gayle M Davey; William R Heath; Yu Kato; Susie Kitsoulis; eta ahmet; Irina Caminschi
Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(2):842-50.
2011: Juliana Idoyaga; Ashira Lubkin; Christopher Fiorese; Mireille H Lahoud; Irina Caminschi; Yaoxing Huang; Anthony Rodriguez; Björn E Clausen; Chae Gyu Park; Christine Trumpfheller; Ralph M Steinman
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(6):2384-9.
2009: Mireille Lahoud; Anna I Proietto; eta ahmet; Susie Kitsoulis; liv eidsmo; Li Wu; Priyanka Sathe; Suzanne Pietersz; Hsuen-Wen Chang; Ian D Walker; Eugene Maraskovsky; Hal Braley; Andrew M Lew; Mark D Wright; William R Heath; Ken Shortman; Irina Caminschi
The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(12):7587-94.
2009: C Lee; T B Kolesnik; Irina Caminschi; A Chakravorty; W Carter; W S Alexander; J Jones; Gary P Anderson; S E Nicholson
Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(6):897-907.
2009: Sammy Bedoui; Paul G Whitney; Jason Waithman; liv eidsmo; Linda Wakim; Irina Caminschi; Rhys S Allan; Magdalena Wojtasiak; Ken Shortman; Francis R Carbone; Andrew G Brooks; William R Heath
Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells.
Nature immunology 2009;10(5):488-95.
2009: Irina Caminschi; Mireille Lahoud; Ken Shortman
Enhancing immune responses by targeting antigen to DC.
European journal of immunology 2009;39(4):931-8.
2009: liv eidsmo; Rhys Allan; Irina Caminschi; Nico van Rooijen; William R Heath; Francis R Carbone
Differential migration of epidermal and dermal dendritic cells during skin infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3165-72.
2009: Ken Shortman; Mireille Lahoud; Irina Caminschi
Improving vaccines by targeting antigens to dendritic cells.
Experimental & molecular medicine 2009;41(2):61-6.
2008: Irina Caminschi; Anna I Proietto; eta ahmet; Susie Kitsoulis; Joo Shin Teh; Jennifer C Y Lo; alexandra rizzitelli; Li Wu; David Vremec; Serani L H van Dommelen; Ian K Campbell; Eugene Maraskovsky; Hal Braley; Gayle M Davey; Patricia Mottram; Nicholas van de Velde; Kent Jensen; Andrew M Lew; Mark D Wright; William R Heath; Ken Shortman; Mireille Lahoud
The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement.
Blood 2008;112(8):3264-73.
2007: Dorothee Bourges; Yifan Zhan; Jamie L Brady; Hal Braley; Irina Caminschi; Sandro Prato; Jose A Villadangos; Andrew M Lew
Targeting the gut vascular endothelium induces gut effector CD8 T cell responses via cross-presentation by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5678-85.
2007: Irina Caminschi; Fatma Ahmet; Klaus Heger; Jason Brady; Stephen L Nutt; David Vremec; Suzanne Pietersz; Mireille Lahoud; Louis Schofield; Diana Hansen; Meredith O'Keeffe; Mark J Smyth; Sammy Bedoui; Gayle M Davey; Jose A Villadangos; William R Heath; Ken Shortman
Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells.
The Journal of experimental medicine 2007;204(11):2579-90.
2007: David Vremec; Meredith O'Keeffe; Hubertus Hochrein; Martina Fuchsberger; Irina Caminschi; Mireille Lahoud; Ken Shortman
Production of interferons by dendritic cells, plasmacytoid cells, natural killer cells, and interferon-producing killer dendritic cells.
Blood 2007;109(3):1165-73.
2006: Mireille Lahoud; Anna I Proietto; Kate H Gartlan; Susie Kitsoulis; Joan Curtis; James Wettenhall; Mariam Sofi; Carmel Daunt; Meredith O'Keeffe; Irina Caminschi; Keith Satterley; alexandra rizzitelli; Petra Schnorrer; Atsushi Hinohara; Yasunori Yamaguchi; Li Wu; Gordon K Smyth; Emanuela Handman; Ken Shortman; Mark D Wright
Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):372-82.
2006: Irina Caminschi; Alexandra J Corbett; Corina Zahra; Mireille Lahoud; Karen M Lucas; Mariam Sofi; David Vremec; Thomas Gramberg; Stefan Pöhlmann; Joan Curtis; Emanuela Handman; Serani L H van Dommelen; Peter Fleming; Mariapia A Degli-Esposti; Ken Shortman; Mark D Wright
Functional comparison of mouse CIRE/mouse DC-SIGN and human DC-SIGN.
International immunology 2006;18(5):741-53.
2006: Thomas Gramberg; Irina Caminschi; Anja Wegele; Heike Hofmann; Stefan Pöhlmann
Evidence that multiple defects in murine DC-SIGN inhibit a functional interaction with pathogens.
Virology 2006;345(2):482-91.
2006: Irina Caminschi; Stephane Vandenabeele; Mariam Sofi; Andrew J McKnight; Neil Ward; Thomas C Brodnicki; Tracey Toy; Mireille Lahoud; Eugene Maraskovsky; Ken Shortman; Mark D Wright
Gene structure and transcript analysis of the human and mouse EGF-TM7 molecule, FIRE.
DNA sequence : the journal of DNA sequencing and mapping 2006;17(1):8-14.
2005: Alexandra J Corbett; Irina Caminschi; Brent S McKenzie; Jamie L Brady; Mark D Wright; Patricia L Mottram; P Mark Hogarth; Anthony N Hodder; Yifan Zhan; David M Tarlinton; Ken Shortman; Andrew M Lew
Antigen delivery via two molecules on the CD8- dendritic cell subset induces humoral immunity in the absence of conventional "danger".
European journal of immunology 2005;35(10):2815-25.
2002: Meredith O'Keeffe; Hubertus Hochrein; David Vremec; Irina Caminschi; Joanna L Miller; E Margot Anders; Li Wu; Mireille Lahoud; Sandrine Henri; Bernadette Scott; Paul J Hertzog; Lilliana Tatarczuch; Ken Shortman
Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus.
The Journal of experimental medicine 2002;196(10):1307-19.
2001: Raelene J Grumont; Hubertus Hochrein; Meredith O'Keeffe; Raffi Gugasyan; C White; Irina Caminschi; W Cook; Steve Gerondakis
c-Rel regulates interleukin 12 p70 expression in CD8(+) dendritic cells by specifically inducing p35 gene transcription.
The Journal of experimental medicine 2001;194(8):1021-32.
2001: Irina Caminschi; Karen M Lucas; Meredith O'Keeffe; Hubertus Hochrein; Yacine LAABI; F Köntgen; Andrew M Lew; Ken Shortman; Mark D Wright
Molecular cloning of F4/80-like-receptor, a seven-span membrane protein expressed differentially by dendritic cell and monocyte-macrophage subpopulations.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(7):3570-6.
2001: Irina Caminschi; Karen M Lucas; Meredith O'Keeffe; Hubertus Hochrein; Yacine LAABI; Thomas C Brodnicki; Andrew M Lew; Ken Shortman; Mark D Wright
Molecular cloning of a C-type lectin superfamily protein differentially expressed by CD8alpha(-) splenic dendritic cells.
Molecular immunology 2001;38(5):365-73.
2001: V Kronin; CJ Fitzmaurice; Irina Caminschi; Ken Shortman; David C Jackson; Lorena E Brown
Differential effect of CD8(+) and CD8(-) dendritic cells in the stimulation of secondary CD4(+) T cells.
International immunology 2001;13(4):465-73.
1999: William R Heath; C Kurts; Irina Caminschi; Francis R Carbone; J F Miller
CD30 prevents T-cell responses to non-lymphoid tissues.
Immunological reviews 1999;169():23-9.