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Michael Schlosser

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Andreas Hoene; Silke Lucke; Hans-Georg Neumann; Maciej Patrzyk; Cornelia Prinz; Uwe Walschus; Lutz Wilhelm; Michael Schlosser
In vivo evaluation of copper release and acute local tissue reactions after implantation of copper-coated titanium implants in rats.
Andreas Hoene; Jürgen Meichsner; Barbara Nebe; Maciej Patrzyk; Andreas Podbielski; Henrike Rebl; Vítězslav Straňák; Holger Testrich; Uwe Walschus; Carmen Zietz; Rainer Bader; Birgit Finke; Rainer Hippler; Michael Schlosser
In vivo examination of the local inflammatory response after implantation of Ti6Al4V samples with a combined low-temperature plasma treatment using pulsed magnetron sputtering of copper and plasma-polymerized ethylenediamine.
Uwe Walschus; Lutz Wilhelm; Karsten Schroeder; Birgit Finke; Andreas Hoene; Silke Lucke; Barbara Nebe; Maciej Patrzyk; Andreas Podbielski; Martin Polak; Michael Schlosser
Serum profile of pro- and anti-inflammatory cytokines in rats following implantation of low-temperature plasma-modified titanium plates.

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All Publications

2013: Andreas Hoene; Silke Lucke; Hans-Georg Neumann; Maciej Patrzyk; Cornelia Prinz; Uwe Walschus; Lutz Wilhelm; Michael Schlosser
In vivo evaluation of copper release and acute local tissue reactions after implantation of copper-coated titanium implants in rats.
Biomedical materials (Bristol, England) 2013;8(3):035009.
2013: Andreas Hoene; Jürgen Meichsner; Barbara Nebe; Maciej Patrzyk; Andreas Podbielski; Henrike Rebl; Vítězslav Straňák; Holger Testrich; Uwe Walschus; Carmen Zietz; Rainer Bader; Birgit Finke; Rainer Hippler; Michael Schlosser
In vivo examination of the local inflammatory response after implantation of Ti6Al4V samples with a combined low-temperature plasma treatment using pulsed magnetron sputtering of copper and plasma-polymerized ethylenediamine.
Journal of materials science. Materials in medicine 2013;24(3):761-71.
2012: Uwe Walschus; Lutz Wilhelm; Karsten Schroeder; Birgit Finke; Andreas Hoene; Silke Lucke; Barbara Nebe; Maciej Patrzyk; Andreas Podbielski; Martin Polak; Michael Schlosser
Serum profile of pro- and anti-inflammatory cytokines in rats following implantation of low-temperature plasma-modified titanium plates.
Journal of materials science. Materials in medicine 2012;23(5):1299-307.
2011: Vito Lampasona; Patricia W Mueller; Michael Schlosser; Janet M Wenzlau; Alistair J K Williams; John C Hutton; Peter Achenbach
Diabetes antibody standardization program: first proficiency evaluation of assays for autoantibodies to zinc transporter 8.
Clinical chemistry 2011;57(12):1693-702.
2011: Michael Schlosser; Peter Achenbach; Polly J Bingley; Vito Lampasona; Patricia W Mueller
Diabetes Antibody Standardization Program: First evaluation of assays for autoantibodies to IA-2β.
Diabetes care 2011;34(11):2410-2.
2011: Alexandra Kochanowski; Andreas Hoene; Maciej Patrzyk; Uwe Walschus; Birgit Finke; Bérengère Luthringer; Frank Feyerabend; Regine Willumeit; Silke Lucke; Michael Schlosser
Examination of the inflammatory response following implantation of titanium plates coated with phospholipids in rats.
Journal of materials science. Materials in medicine 2011;22(4):1015-26.
2011: U Walschus; Andreas Hoene; A Kochanowski; B Neukirch; Maciej Patrzyk; Lutz Wilhelm; K Schröder; Michael Schlosser
Quantitative immunohistochemical examination of the local cellular reactions following implantation of biomaterials.
Journal of microscopy 2011;242(1):94-9.
2010: Michael Schlosser; P W Mueller; C Törn; Ezio Bonifacio; P J Bingley
Diabetes Antibody Standardization Program: evaluation of assays for insulin autoantibodies.
Diabetologia 2010;53(12):2611-20.
2010: Maciej Patrzyk; Andreas Hoene; Raymond Jarchow; Lutz Wilhelm; Uwe Walschus; Roland Zippel; Michael Schlosser
Time course of fibronectin in the peri-implant tissue and neointima formation after functional implantation of polyester-based vascular prostheses with different porosity in pigs.
Biomedical materials (Bristol, England) 2010;5(5):055003.
2010: Andreas Hoene; U Walschus; Maciej Patrzyk; B Finke; S Lucke; B Nebe; K Schroeder; A Ohl; Michael Schlosser
In vivo investigation of the inflammatory response against allylamine plasma polymer coated titanium implants in a rat model.
Acta biomaterialia 2010;6(2):676-83.
2009: Uwe Walschus; Andreas Hoene; Hans-Georg Neumann; Lutz Wilhelm; Silke Lucke; Frank Lüthen; Joachim Rychly; Michael Schlosser
Morphometric immunohistochemical examination of the inflammatory tissue reaction after implantation of calcium phosphate-coated titanium plates in rats.
Acta biomaterialia 2009;5(2):776-84.
2008: C Törn; P W Mueller; Michael Schlosser; E Bonifacio; P J Bingley
Diabetes Antibody Standardization Program: evaluation of assays for autoantibodies to glutamic acid decarboxylase and islet antigen-2.
Diabetologia 2008;51(5):846-52.
2008: Roland Zippel; Lutz Wilhelm; Andreas Hoene; Uwe Walschus; Torsten Ueberrueck; Michael Schlosser
Local tissue reaction and differentiation of the prosthesis-specific antibody response following functional implantation of vascular grafts in pigs.
Journal of biomedical materials research. Part B, Applied biomaterials 2008;85(2):334-42.
2008: Uwe Walschus; Helmut Goldmann; Torsten Ueberrueck; Andreas Hoene; Lutz Wilhelm; Michael Schlosser
Evaluation of the biocompatibility of a new vascular prosthesis coating by detection of prosthesis-specific antibodies.
Journal of materials science. Materials in medicine 2008;19(4):1595-600.
2008: Michael Schlosser; Uwe Walschus; Ingrid Klöting; Reinhard Walther
Determination of glutamic acid decarboxylase (GAD65) in pancreatic islets and its in vitro and in vivo degradation kinetics in serum using a highly sensitive enzyme immunoassay.
Disease markers 2008;24(3):191-8.
2007: Tarvo Rajasalu; Kadri Haller; Liina Salur; Kai E Kisand; Vallo Tillmann; Michael Schlosser; Raivo Uibo
Insulin VNTR I/III genotype is associated with autoantibodies against glutamic acid decarboxylase in newly diagnosed type 1 diabetes.
Diabetes/metabolism research and reviews 2007;23(7):567-71.
2007: Lutz Wilhelm; Roland Zippel; Th von Woedtke; Heidrun Kenk; Andreas Hoene; Maciej Patrzyk; Michael Schlosser
Immune response against polyester implants is influenced by the coating substances.
Journal of biomedical materials research. Part A 2007;83(1):104-13.
2007: Anja Mayr; Michael Schlosser; Natalie Grober; Heidrun Kenk; Anette-G Ziegler; Ezio Bonifacio; Peter Achenbach
GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes.
Diabetes 2007;56(6):1527-33.
2007: Peter Achenbach; Michael Schlosser; Alistair J K Williams; Liping Yu; Patricia W Mueller; Polly J Bingley; Ezio Bonifacio
Combined testing of antibody titer and affinity improves insulin autoantibody measurement: Diabetes Antibody Standardization Program.
Clinical immunology (Orlando, Fla.) 2007;122(1):85-90.
2006: Roland Zippel; Andreas Hoene; Uwe Walschus; Raymond Jarchow; Torsten Ueberrueck; Maciej Patrzyk; Michael Schlosser; Lutz Wilhelm
Digital image analysis for morphometric evaluation of tissue response after implanting alloplastic vascular prostheses.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2006;12(5):366-75.
2006: Josef Endl; Silke Rosinger; Barbara Schwarz; Sven-Olaf Friedrich; Gregor Rothe; Wolfram Karges; Michael Schlosser; Thomas Eiermann; Dolores Schendel; Bernhard O Boehm
Coexpression of CD25 and OX40 (CD134) receptors delineates autoreactive T-cells in type 1 diabetes.
Diabetes 2006;55(1):50-60.
2005: Ivana Durinovic-Belló; Eva Jelinek; Michael Schlosser; Thomas Eiermann; Bernhard O Boehm; Wolfram Karges; Luc Marchand; Constantin Polychronakos
Class III alleles at the insulin VNTR polymorphism are associated with regulatory T-cell responses to proinsulin epitopes in HLA-DR4, DQ8 individuals.
Diabetes 2005;54 Suppl 2():S18-24.
2005: V Moya-Suri; Michael Schlosser; K Zimmermann; Ilona Rjasanowski; Lutz G Gürtler; Renate Mentel
Enterovirus RNA sequences in sera of schoolchildren in the general population and their association with type 1-diabetes-associated autoantibodies.
Journal of medical microbiology 2005;54(Pt 9):879-83.
2005: Michael Schlosser; Kerstin Koczwara; Heidrun Kenk; Martina Strebelow; Ilona Rjasanowski; Ralf Wassmuth; Peter Achenbach; Anette-G Ziegler; Ezio Bonifacio
In insulin-autoantibody-positive children from the general population, antibody affinity identifies those at high and low risk.
Diabetologia 2005;48(9):1830-2.
2005: Christiane S Hampe; Angela R Wallen; Michael Schlosser; Manfred Ziegler; Ian R Sweet
Quantitative evaluation of a monoclonal antibody and its fragment as potential markers for pancreatic beta cell mass.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(7):381-7.
2005: Michael Schlosser; J Paul Banga; Anne-Marie Madec; Katherine A Binder; Martina Strebelow; Ilona Rjasanowski; Ralf Wassmuth; Lisa K Gilliam; Dong Luo; Christiane S Hampe
Dynamic changes of GAD65 autoantibody epitope specificities in individuals at risk of developing type 1 diabetes.
Diabetologia 2005;48(5):922-30.
2005: Michael Schlosser; Roland Zippel; Andreas Hoene; G Urban; Torsten Ueberrueck; F Marusch; A Koch; L Meyer; Lutz Wilhelm
Antibody response to collagen after functional implantation of different polyester vascular prostheses in pigs.
Journal of biomedical materials research. Part A 2005;72(3):317-25.
2004: Michael Schlosser; Martina Strebelow; Ilona Rjasanowski; Wolfgang Kerner; Ralf Wassmuth; Manfred Ziegler
Prevalence of diabetes-associated autoantibodies in schoolchildren: the Karlsburg Type 1 Diabetes Risk Study.
Annals of the New York Academy of Sciences 2004;1037():114-7.
2004: Silvia Rathmann; Tarvo Rajasalu; Silke Rosinger; Michael Schlosser; Thomas Eiermann; Bernhard O Boehm; Ivana Durinovic-Belló
Preproinsulin-specific CD8+ T cells secrete IFNgamma in human type 1 diabetes.
Annals of the New York Academy of Sciences 2004;1037():22-5.
2004: Ivana Durinovic-Belló; Michael Schlosser; M Riedl; Nicola Maisel; Silke Rosinger; Hubert Kalbacher; Martin Deeg; M Ziegler; J Elliott; Bart O Roep; Wolfram Karges; Bernhard O Boehm
Pro- and anti-inflammatory cytokine production by autoimmune T cells against preproinsulin in HLA-DRB1*04, DQ8 Type 1 diabetes.
Diabetologia 2004;47(3):439-50.
2003: Th von Woedtke; Michael Schlosser; G Urban; Vera Hartmann; Wolf-Dieter Jülich; PU Abel; Lutz Wilhelm
The influence of antimicrobial treatments on the cytocompatibility of polyurethane biosensor membranes.
Biosensors & bioelectronics 2003;19(3):269-76.
2003: Ivana Durinovic-Belló; Nicola Maisel; Michael Schlosser; Hubert Kalbacher; Martin Deeg; Thomas Eiermann; Wolfram Karges; Bernhard O Boehm
Relationship between T and B cell responses to proinsulin in human type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():288-94.
2003: Michael Schlosser; Ralf Wassmuth; Martina Strebelow; Ilona Rjasanowski; Manfred Ziegler
Multiple and high-titer single autoantibodies in schoolchildren reflecting the genetic predisposition for type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():98-108.
2003: Carolyn Padoa; J Paul Banga; Anne-Marie Madec; Manfred Ziegler; Michael Schlosser; Eva Ortqvist; Ingrid Kockum; Jerry Palmer; Olov Rolandsson; Katherine A Binder; Jefferson Foote; Dong Luo; Christiane S Hampe
Recombinant Fabs of human monoclonal antibodies specific to the middle epitope of GAD65 inhibit type 1 diabetes-specific GAD65Abs.
Diabetes 2003;52(11):2689-95.
2002: Michael Schlosser; Lutz Wilhelm; G Urban; Brigitte Ziegler; Manfred Ziegler; Roland Zippel
Immunogenicity of polymeric implants: long-term antibody response against polyester (Dacron) following the implantation of vascular prostheses into LEW.1A rats.
Journal of biomedical materials research 2002;61(3):450-7.
2002: Michael Schlosser; Martina Strebelow; Ralf Wassmuth; Marie-Luise Arnold; Isabel Breunig; Ilona Rjasanowski; Brigitte Ziegler; Manfred Ziegler
The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals.
The Journal of clinical endocrinology and metabolism 2002;87(5):2254-61.
2002: Ivana Durinovic-Belló; Martina Riedl; Silke Rosinger; Nicola Maisel; Hubert Kalbacher; Martin Deeg; Hans-Jürgen Schreckling; Michael Schlosser; Manfred Ziegler; Peter Kuehnl; Bernhard O Boehm
Th2 dominance of T helper cell response to preproinsulin in individuals with preclinical type 1 diabetes.
Annals of the New York Academy of Sciences 2002;958():209-13.
2001: Roland Zippel; Lutz Wilhelm; Frank Marusch; A Koch; G Urban; Michael Schlosser
Antigenicity of polyester (Dacron) vascular prostheses in an animal model.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 2001;21(3):202-7.
1999: Martina Strebelow; Michael Schlosser; Brigitte Ziegler; Ilona Rjasanowski; Manfred Ziegler
Karlsburg Type I diabetes risk study of a general population: frequencies and interactions of the four major Type I diabetes-associated autoantibodies studied in 9419 schoolchildren.
Diabetologia 1999;42(6):661-70.
1998: Brigitte Ziegler; Martina Strebelow; Ilona Rjasanowski; Michael Schlosser; Manfred Ziegler
A monoclonal antibody-based characterization of autoantibodies against glutamic acid decarboxylase in adults with latent autoimmune diabetes.
Autoimmunity 1998;28(2):61-8.
1997: Michael Schlosser; J Hahmann; Brigitte Ziegler; Petra Augstein; Manfred Ziegler
Sensitive monoclonal antibody-based sandwich ELISA for determination of the diabetes-associated autoantigen glutamic acid decarboxylase GAD65.
Journal of immunoassay 1997;18(4):289-307.
1997: Petra Augstein; Brigitte Ziegler; Michael Schlosser; S Flassig; Martina Strebelow; Manfred Ziegler
Immunohistochemical differentiation of monoclonal GAD antibodies recognizing linear or conformational epitope regions.
Pancreas 1997;15(2):139-46.
1996: Brigitte Ziegler; Michael Schlosser; F Lühder; Martina Strebelow; Petra Augstein; W Northemann; A C Powers; Manfred Ziegler
Murine monoclonal glutamic acid decarboxylase (GAD)65 antibodies recognize autoimmune-associated GAD epitope regions targeted in patients with type 1 diabetes mellitus and stiff-man syndrome.
Acta diabetologica 1996;33(3):225-31.
1996: Petra Augstein; Michael Schlosser; Brigitte Ziegler; J Hahmann; L Mauch; Manfred Ziegler
Comparison of the islet cell antibody pattern of monoclonal glutamic acid decarboxylase antibodies recognizing linear and conformational epitopes.
Acta histochemica 1996;98(2):229-41.
1996: Brigitte Ziegler; Petra Augstein; D Schröder; L Mauch; J Hahmann; Michael Schlosser; Manfred Ziegler
Glutamate decarboxylase (GAD) is not detectable on the surface of rat islet cells examined by cytofluorometry and complement-dependent antibody-mediated cytotoxicity of monoclonal GAD antibodies.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1996;28(1):11-5.
1994: Michael Schlosser; Brigitte Ziegler; P Abel; U Fischer; Manfred Ziegler
Implantation of non-toxic materials from glucose sensors: evidence for specific antibodies detected by ELISA.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1994;26(11):534-7.
1994: F Lühder; Michael Schlosser; D Michaelis; Brigitte Ziegler; K D Kohnert; Manfred Ziegler
No association between anti-bovine serum albumin antibodies and islet cell reactive antibodies in newly diagnosed type 1 diabetic patients.
Diabetes research and clinical practice 1994;26(1):35-41.
1994: Manfred Ziegler; Michael Schlosser; P Abel; Brigitte Ziegler
Antibody response in rats against non-toxic glucose sensor membranes tested in cell culture.
Biomaterials 1994;15(10):859-64.
1994: Manfred Ziegler; Michael Schlosser; J Hamann; Peter Vieregge; F Lühder; Ingrid Klöting; Brigitte Ziegler
Autoantibodies to glutamate decarboxylase detected in diabetes-prone BB/OK rats do not distinguish onset of diabetes.
Experimental and clinical endocrinology 1994;102(2):98-103.
1994: F Lühder; Michael Schlosser; L Mauch; H Haubruck; Ilona Rjasanowski; D Michaelis; K D Kohnert; Manfred Ziegler
Autoantibodies against GAD65 rather than GAD67 precede the onset of type 1 diabetes.
Autoimmunity 1994;19(2):71-80.
1994: Michael Schlosser; Brigitte Ziegler; Petra Augstein; Ingrid Klöting; Manfred Ziegler
Occurrence of islet cell reactive autoantibodies in diabetes-prone BB/OK rats is not associated with the onset of diabetes: a cross-sectional study of BB rats and their diabetes-resistant congenic strains.
Diabetes research (Edinburgh, Scotland) 1994;26(2):67-77.
1994: Brigitte Ziegler; Petra Augstein; F Lühder; W Northemann; J Hamann; Michael Schlosser; Ingrid Klöting; D Michaelis; Manfred Ziegler
Monoclonal antibodies specific to the glutamic acid decarboxylase 65 kDa isoform derived from a non-obese diabetic (NOD) mouse.
Diabetes research (Edinburgh, Scotland) 1994;25(2):47-64.
1993: Brigitte Ziegler; Sabine Witt; K D Kohnert; Michael Schlosser; Petra Augstein; D Michaelis; Ingrid Klöting; Manfred Ziegler
Characterization of monoclonal islet cell reactive autoantibodies from the diabetic biobreeding (BB/OK) rat.
Acta diabetologica 1993;30(4):201-6.
1992: Brigitte Ziegler; S Lucke; E Köhler; B Hehmke; Michael Schlosser; Sabine Witt; W Besch; Manfred Ziegler
Monoclonal antibody-mediated cytotoxicity against rat beta cells detected in vitro does not cause beta-cell destruction in vivo.
Diabetologia 1992;35(7):608-13.
1991: Michael Schlosser; Sabine Witt; Birgitt Fürll; Brigitte Ziegler; Manfred Ziegler
Different multiple reactivity of monoclonal islet cell binding antibodies using indirect immunofluorescence technique on viable cells or cellular ELISA on desiccated cells as target.
Diabetes research (Edinburgh, Scotland) 1991;17(3):147-55.
1991: Michael Schlosser; Sabine Witt; Brigitte Ziegler; M Ziegler
Influence of target cell preparation on binding of monoclonal islet cell reactive antibodies (mc-ICRA) in cellular enzyme-linked immunosorbent assay (CELISA).
Journal of immunological methods 1991;140(1):101-9.
1991: Brigitte Ziegler; Michael Schlosser; Birgitt Fürll; Sabine Witt; Manfred Ziegler
CELISA for rapid screening of monoclonal islet cell surface antibodies using living rat insulinoma cells as target.
Diabetes research (Edinburgh, Scotland) 1991;16(1):41-5.
1991: Sabine Witt; Brigitte Ziegler; C Blumentritt; Michael Schlosser; M Ziegler
[Production of monoclonal antibodies in serum-free medium in dialysis tubing].
Allergie und Immunologie 1991;37(2):67-74.
1990: Brigitte Ziegler; Michael Schlosser; Sabine Witt; P Bürgelt; M Ziegler
[Binding of monoclonal antibodies to an insulin-producing rat tumor cell (RIN) after partial cell synchronization].
Acta histochemica. Supplementband 1990;39():443-9.
1989: Brigitte Ziegler; Peter Heinke; Michael Schlosser; Ilona Rjasanowski; D Michaelis; Manfred Ziegler
Determination of islet cell surface antibodies in first-degree relatives of type 1 diabetic patients using rat insulinoma cells.
Diabetes research (Edinburgh, Scotland) 1989;12(1):25-9.
1989: I Hulinsky; Brigitte Ziegler; E Cabrera; Michael Schlosser; Sabine Witt; Manfred Ziegler
Monoclonal islet cell surface antibody dependent cellular cytotoxicity mediated by rat splenocytes with the RIN cell line as target.
Experimental and clinical endocrinology 1989;93(2-3):181-6.
1989: Brigitte Ziegler; Sabine Witt; B Waterstradt; Michael Schlosser; Manfred Ziegler
Heterogeneity of monoclonal antibodies against pancreatic beta cells.
Experimental and clinical endocrinology 1989;93(2-3):173-80.