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Tim Williams

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Publications

TOP 3
Tao Chen; Carolin Hamberger; Kevin Hickling; Angela Mally; Leda Mirbahai; Tim Williams; J Kevin Chipman
Gene expression and epigenetic changes by furan in rat liver.
Leda Mirbahai; Tim Williams; Guangliang Yin; John Bignell; Ning Li; James K Chipman
DNA methylation in liver tumorigenesis in fish from the environment.
Tim Williams; Huifeng Wu; Joseph K Abraham; Katie L Bartie; Kevin J Chipman; Amer M Diab; Stephen G George; John M Herbert; Olga Hrydziuszko; Ioanna Katsiadaki; Michael J Leaver; Brett P Lyons; Carolynn Mackenzie; Grant D Stentiford; John B Taggart; Nil Turan; Mark R Viant; Francesco Falciani
Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach.

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All Publications

2012: Tao Chen; Carolin Hamberger; Kevin Hickling; Angela Mally; Leda Mirbahai; Tim Williams; J Kevin Chipman
Gene expression and epigenetic changes by furan in rat liver.
Toxicology 2012;292(2-3):63-70.
2011: Leda Mirbahai; Tim Williams; Guangliang Yin; John Bignell; Ning Li; James K Chipman
DNA methylation in liver tumorigenesis in fish from the environment.
Epigenetics : official journal of the DNA Methylation Society 2011;6(11):1319-33.
2011: Tim Williams; Huifeng Wu; Joseph K Abraham; Katie L Bartie; Kevin J Chipman; Amer M Diab; Stephen G George; John M Herbert; Olga Hrydziuszko; Ioanna Katsiadaki; Michael J Leaver; Brett P Lyons; Carolynn Mackenzie; Grant D Stentiford; John B Taggart; Nil Turan; Mark R Viant; Francesco Falciani
Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach.
PLoS computational biology 2011;7(8):e1002126.
2011: Rhiannon M David; Tim Williams; Matthew J Winter; Vanja Dakic; J Kevin Chipman
Transcriptional responses in neonate and adult Daphnia magna in relation to relative susceptibility to genotoxicants.
Aquatic toxicology (Amsterdam, Netherlands) 2011;104(3-4):192-204.
2011: Leda Mirbahai; Tim Williams; Huiqing Zhan; Zhiyuan Gong; J Kevin Chipman
Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis.
BMC genomics 2011;12():3.
2011: R M Harris; Tim Williams; N J Hodges; R H Waring
Reactive oxygen species and oxidative DNA damage mediate the cytotoxicity of tungsten-nickel-cobalt alloys in vitro.
Toxicology and applied pharmacology 2011;250(1):19-28.
2010: Ioanna Katsiadaki; Tim Williams; Jonathan S Ball; Tim P Bean; Matthew B Sanders; Huifeng Wu; Eduarda M Santos; Margaret M Brown; Paul Baker; Fernando Ortega; Francesco Falciani; John A Craft; Charles R Tyler; Mark R Viant; James K Chipman
Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.
Aquatic toxicology (Amsterdam, Netherlands) 2010;97(3):174-87.
2010: Michael J Leaver; Amer Diab; Evridiki Boukouvala; Tim Williams; J Kevin Chipman; Colin F Moffat; Craig D Robinson; Stephen G George
Hepatic gene expression in flounder chronically exposed to multiply polluted estuarine sediment: Absence of classical exposure 'biomarker' signals and induction of inflammatory, innate immune and apoptotic pathways.
Aquatic toxicology (Amsterdam, Netherlands) 2010;96(3):234-45.
2010: Hamish J Small; Tim Williams; Joachim Sturve; James K Chipman; Andrew D Southam; Tim P Bean; Brett P Lyons; Grant D Stentiford
Gene expression analyses of hepatocellular adenoma and hepatocellular carcinoma from the marine flatfish Limanda limanda.
Diseases of aquatic organisms 2010;88(2):127-41.
2010: Eduarda M Santos; Jonathan S Ball; Tim Williams; Huifeng Wu; Fernando Ortega; Ronny van Aerle; Ioanna Katsiadaki; Francesco Falciani; Mark R Viant; James K Chipman; Charles R Tyler
Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model.
Environmental science & technology 2010;44(2):820-6.
2010: Graham Van Aggelen; Gerald T Ankley; William S Baldwin; Daniel W Bearden; William H Benson; J Kevin Chipman; Tim W Collette; John A Craft; Nancy D Denslow; Michael R Embry; Francesco Falciani; Stephen G George; Caren C Helbing; Paul F Hoekstra; Taisen Iguchi; Yoshi Kagami; Ioanna Katsiadaki; Peter Kille; Li Liu; Peter Lord; Terry McIntyre; Anne O'Neill; Heather Osachoff; Ed J Perkins; Eduarda M Santos; Rachel C Skirrow; Jason R Snape; Charles R Tyler; Don Versteeg; Mark R Viant; David C Volz; Tim Williams; Lorraine Yu
Integrating omic technologies into aquatic ecological risk assessment and environmental monitoring: hurdles, achievements, and future outlook.
Environmental health perspectives 2010;118(1):1-5.
2009: Tim Williams; Huifeng Wu; Eduarda M Santos; Jon Ball; Ioanna Katsiadaki; Margaret M Brown; Paul Baker; Fernando Ortega; Francesco Falciani; John A Craft; Charles R Tyler; James K Chipman; Mark R Viant
Hepatic transcriptomic and metabolomic responses in the stickleback (Gasterosteus aculeatus) exposed to environmentally relevant concentrations of dibenzanthracene.
Environmental science & technology 2009;43(16):6341-8.
2009: Inmaculada Osuna-Jiménez; Tim Williams; María-José Prieto-Alamo; Nieves Abril; J Kevin Chipman; Carmen Pueyo
Immune- and stress-related transcriptomic responses of Solea senegalensis stimulated with lipopolysaccharide and copper sulphate using heterologous cDNA microarrays.
Fish & shellfish immunology 2009;26(5):699-706.
2009: Stanley O Aniagu; Tim Williams; J Kevin Chipman
Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-beta oestradiol.
Toxicology 2009;256(3):143-51.
2008: Francesco Falciani; A M Diab; V Sabine; Tim Williams; F Ortega; Stephen G George; James K Chipman
Hepatic transcriptomic profiles of European flounder (Platichthys flesus) from field sites and computational approaches to predict site from stress gene responses following exposure to model toxicants.
Aquatic toxicology (Amsterdam, Netherlands) 2008;90(2):92-101.
2008: Tim Williams; Amer Diab; Fernando Ortega; Victoria S Sabine; Rita E Godfrey; Francesco Falciani; James K Chipman; Stephen G George
Transcriptomic responses of European flounder (Platichthys flesus) to model toxicants.
Aquatic toxicology (Amsterdam, Netherlands) 2008;90(2):83-91.
2008: P F Larsen; Einar E Nielsen; Tim Williams; Volker Loeschcke
Intraspecific variation in expression of candidate genes for osmoregulation, heme biosynthesis and stress resistance suggests local adaptation in European flounder (Platichthys flesus).
Heredity 2008;101(3):247-59.
2008: Margaret M Brown; Tim Williams; J Kevin Chipman; Ioanna Katsiadaki; Matthew Sanders; John A Craft
Construction of subtracted EST and normalised cDNA libraries from liver of chemical-exposed three-spined stickleback (Gasterosteus aculeatus) containing pollutant-responsive genes as a resource for transcriptome analysis.
Marine environmental research 2008;66(1):127-30.
2008: Stefan Götz; Juan Miguel García-Gómez; Javier Terol; Tim Williams; Shivashankar H Nagaraj; María José Nueda; Montserrat Robles; Manuel Talón; Joaquín Dopazo; Ana Conesa
High-throughput functional annotation and data mining with the Blast2GO suite.
Nucleic acids research 2008;36(10):3420-35.
2008: Stanley O Aniagu; Tim Williams; Yvonne Allen; Ioanna Katsiadaki; J Kevin Chipman
Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol.
Environment international 2008;34(3):310-7.
2007: Peter F Larsen; Einar E Nielsen; Tim Williams; Jakob Hemmer-Hansen; James K Chipman; Mogens Kruhøffer; Peter Grønkjaer; Stephen G George; Lars Dyrskjøt; Volker Loeschcke
Adaptive differences in gene expression in European flounder (Platichthys flesus).
Molecular ecology 2007;16(22):4674-83.
2007: Raphael Cohen; Vered Chalifa-Caspi; Tim Williams; Meirav Auslander; Stephen G George; James K Chipman; Moshe Tom
Estimating the efficiency of fish cross-species cDNA microarray hybridization.
Marine biotechnology (New York, N.Y.) 2007;9(4):491-9.
2007: Tim Williams; Amer M Diab; Stephen G George; Victoria Sabine; James K Chipman
Gene expression responses of European flounder (Platichthys flesus) to 17-beta estradiol.
Toxicology letters 2007;168(3):236-48.
2006: Tim Williams; Amer M Diab; Stephen G George; Rita E Godfrey; Victoria Sabine; Ana Conesa; Stephen D Minchin; Phil C Watts; James K Chipman
Development of the GENIPOL European flounder (Platichthys flesus) microarray and determination of temporal transcriptional responses to cadmium at low dose.
Environmental science & technology 2006;40(20):6479-88.
2006: Nick A Lewis; Tim Williams; James K Chipman
Functional analysis of a metal response element in the regulatory region of flounder cytochrome P450 1A and implications for environmental monitoring of pollutants.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(2):387-93.
2006: Derek L Sheader; Tim Williams; Brett P Lyons; James K Chipman
Oxidative stress response of European flounder (Platichthys flesus) to cadmium determined by a custom cDNA microarray.
Marine environmental research 2006;62(1):33-44.
2005: Young-Mi Lee; Tim Williams; Sang-Oun Jung; Jae-Seong Lee
cDNA cloning and expression of a cytochrome P450 1A (CYP1A) gene from the hermaphroditic fish Rivulus marmoratus.
Marine pollution bulletin 2005;51(8-12):769-75.
2004: Il-Chan Kim; Sung Yeoul Chang; Tim Williams; Young Ja Kim; Yongdal Yoon; Yong-Sung Lee; Eun-Ho Park; Jae-Seong Lee
Genomic cloning and expression of vitellogenin gene from the self-fertilizing fish Rivulus marmoratus (Cyprinodontiformes, Rivulidae).
Marine environmental research 2004;58(2-5):687-91.
2004: Nicholas Lewis; Tim Williams; Kevin Chipman
Functional analysis of xenobiotic response elements (XREs) in CYP 1A of the European Flounder (Platichthys flesus).
Marine environmental research 2004;58(2-5):101-5.
2004: Il-Chan Kim; Young Ja Kim; Young-Mi Lee; Bok-Geon Kim; Tae-Jin Park; Hyeung-Sin Kim; Min-Min Jung; Tim Williams; Wonchoel Lee; Jae-Seong Lee
cDNA cloning of translationally controlled tumor protein/histamine releasing factor (TCTP/HRF) from the intertidal harpacticoid copepod Tigriopus japonicus.
DNA sequence : the journal of DNA sequencing and mapping 2004;15(2):159-63.
2003: Tim Williams; Karl Gensberg; Stephen D Minchin; James K Chipman
A DNA expression array to detect toxic stress response in European flounder (Platichthys flesus).
Aquatic toxicology (Amsterdam, Netherlands) 2003;65(2):141-57.
2000: Tim Williams; JS Lee; Derek L Sheader; James K Chipman
The cytochrome P450 1A gene (CYP1A) from European flounder (Platichthys flesus), analysis of regulatory regions and development of a dual luciferase reporter gene system.
Marine environmental research 2000;50(1-5):1-6.
1999: Nicolas P Burton; Tim Williams; Paul R Norris
Carboxylase genes of Sulfolobus metallicus.
Archives of microbiology 1999;172(6):349-53.
1995: N P Burton; Tim Williams; P R Norris
A potential anti-oxidant protein in a ferrous iron-oxidizing Sulfolobus species.
FEMS microbiology letters 1995;134(1):91-5.