Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Csaba Szabó

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Physiology

Enzyme Activation

Disorders

Anatomy

Procedures

Immunohistochemistry

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
68
Salzman, Andrew
61
Virag, Laszlo
61
Mabley, Jon
59
Pacher, Pal
55
Haskó, György
40
Salzman, Andrew
35
Liaudet, Lucas
25
Zingarelli, Basilia
24
Southan, Garry
21
Szabó, Gábor Viktor
21
Deitch, Edwin
20
Horváth, Eszter
20
Soriano, Francisco
19
Zsengellér, Zsuzsanna
19
Thiemermann, Christoph

Sign-in to see all Coauthors

Publications

TOP 3
Módis Katalin; Gero Domokos; Nagy Nóra; Szoleczky Petra; Tóth Zoltán Dóri; Szabó Csaba
Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.
Esechie Aimalohi; Enkhbaatar Perenlei; Traber Daniel L; Jonkam Collette; Lange Matthias; Hamahata Atsumori; Djukom Clarisse; Whorton Elbert B; Hawkins Hal K; Traber Lillian D; Szabo Csaba
Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury.
Sodha Neel R; Clements Richard T; Feng Jun; Liu Yuhong; Bianchi Cesario; Horvath Eszter M; Szabo Csaba; Stahl Gregory L; Sellke Frank W
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Csaba Szabó (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Módis Katalin; Gero Domokos; Nagy Nóra; Szoleczky Petra; Tóth Zoltán Dóri; Szabó Csaba
Cytoprotective effects of adenosine and inosine in an in vitro model of acute tubular necrosis.
British journal of pharmacology 2009;158(6):1565-78.
2009: Esechie Aimalohi; Enkhbaatar Perenlei; Traber Daniel L; Jonkam Collette; Lange Matthias; Hamahata Atsumori; Djukom Clarisse; Whorton Elbert B; Hawkins Hal K; Traber Lillian D; Szabo Csaba
Beneficial effect of a hydrogen sulphide donor (sodium sulphide) in an ovine model of burn- and smoke-induced acute lung injury.
British journal of pharmacology 2009;158(6):1442-53.
2009: Sodha Neel R; Clements Richard T; Feng Jun; Liu Yuhong; Bianchi Cesario; Horvath Eszter M; Szabo Csaba; Stahl Gregory L; Sellke Frank W
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury.
The Journal of thoracic and cardiovascular surgery 2009;138(4):977-84.
2009: Osipov Robert M; Robich Michael P; Feng Jun; Liu Yuhong; Clements Richard T; Glazer Hilary P; Sodha Neel R; Szabo Csaba; Bianchi Cesario; Sellke Frank W
Effect of hydrogen sulfide in a porcine model of myocardial ischemia-reperfusion: comparison of different administration regimens and characterization of the cellular mechanisms of protection.
Journal of cardiovascular pharmacology 2009;54(4):287-97.
2009: Erdélyi Katalin; Bai Péter; Kovács István; Szabó Eva; Mocsár Gábor; Kakuk Annamária; Szabó Csaba; Gergely Pál; Virág László
Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(10):3553-63.
2009: Horváth E M; Magenheim R; Kugler E; Vácz G; Szigethy A; Lévárdi F; Kollai M; Szabo C; Lacza Z
Nitrative stress and poly(ADP-ribose) polymerase activation in healthy and gestational diabetic pregnancies.
Diabetologia 2009;52(9):1935-43.
2009: Mabley Jon G; Pacher Pal; Murthy Kanneganti G K; Williams William; Southan Garry J; Salzman Andrew L; Szabo Csaba
The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.
Shock (Augusta, Ga.) 2009;32(3):258-62.
2009: Insko Michael A; Deckwerth Thomas L; Hill Paul; Toombs Christopher F; Szabo Csaba
Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide.
British journal of pharmacology 2009;157(6):944-51.
2009: Reinemund Jana; Seidel Kerstin; Steckelings Ulrike M; Zaade Daniela; Klare Sabrina; Rompe Franziska; Katerbaum Marlen; Schacherl Jens; Li Yaosi; Menk Mario; Schefe Jan H; Goldin-Lang Petra; Szabo Csaba; Olah Gabor; Unger Thomas; Funke-Kaiser Heiko
Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes.
Biochemical pharmacology 2009;77(12):1795-805.
2009: Ajtay Zénó; Scalera Fortunato; Cziráki Attila; Horváth Iván; Papp Lajos; Sulyok Endre; Szabo Csaba; Martens-Lobenhoffer Jens; Awiszus Friedemann; Bode-Böger Stefanie M
Stent placement in patients with coronary heart disease decreases plasma levels of the endogenous nitric oxide synthase inhibitor ADMA.
International journal of molecular medicine 2009;23(5):651-7.
2009: Mukhopadhyay Partha; Rajesh Mohanraj; Bátkai Sándor; Kashiwaya Yoshihiro; Haskó György; Liaudet Lucas; Szabó Csaba; Pacher Pál
Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.
American journal of physiology. Heart and circulatory physiology 2009;296(5):H1466-83.
2009: Horváth E M; Benko R; Kiss L; Murányi M; Pék T; Fekete K; Bárány T; Somlai A; Csordás A; Szabo C
Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus.
Diabetologia 2009;52(5):952-61.
2009: Mabley Jon G; Pacher Pal; Szabo Csaba
Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.
Molecular medicine (Cambridge, Mass.) 2009;15(5-6):166-72.
2009: Pankotai Eszter; Lacza Zsombor; Murányi Marianna; Szabó Csaba
Intra-mitochondrial poly(ADP-ribosyl)ation: potential role for alpha-ketoglutarate dehydrogenase.
Mitochondrion 2009;9(2):159-64.
2009: Cai Bolin; Chen Fei; Lin Xingchun; Miller Edmund; Szabo Csaba; Deitch Edwin A; Ulloa Lusi
Anti-inflammatory adjuvant in resuscitation fluids improves survival in hemorrhage.
Critical care medicine 2009;37(3):860-8.
2009: Szabo Csaba
Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction.
British journal of pharmacology 2009;156(5):713-27.
2009: Szabo Csaba
Poly(ADP-ribose) activation in circulating cells in human myocardial infarction.
International journal of cardiology 2009;132(2):273-4; author reply 274-5.
2009: Enkhbaatar Perenlei; Connelly Rhykka; Wang Jianpu; Nakano Yoshimitsu; Lange Matthias; Hamahata Atsumori; Horvath Eszter; Szabo Csaba; Jaroch Stefan; Hölscher Peter; Hillmann Margrit; Traber Lillian D; Schmalstieg Frank C; Herndon David N; Traber Daniel L
Inhibition of neuronal nitric oxide synthase in ovine model of acute lung injury.
Critical care medicine 2009;37(1):208-14.
2009: Bai Peter; Hegedus Csaba; Szabó Eva; Gyüre László; Bakondi Edina; Brunyánszki Attila; Gergely Szabolcs; Szabó Csaba; Virág László
Poly(ADP-ribose) polymerase mediates inflammation in a mouse model of contact hypersensitivity.
The Journal of investigative dermatology 2009;129(1):234-8.
2009: Wagner Florian; Asfar Pierre; Calzia Enrico; Radermacher Peter; Szabó Csaba
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care.
Critical care (London, England) 2009;13(3):213.
2008: Maybauer Dirk M; Maybauer Marc O; Szabó Csaba; Westphal Martin; Traber Lillian D; Enkhbaatar Perenlei; Murthy Kanneganti G K; Nakano Yoshimitsu; Salzman Andrew L; Herndon David N; Traber Daniel L
Lung-protective effects of the metalloporphyrinic peroxynitrite decomposition catalyst WW-85 in interleukin-2 induced toxicity.
Biochemical and biophysical research communications 2008;377(3):786-91.
2008: Radovits Tamás; Gerö Domokos; Lin Li-ni; Loganathan Sivakkanan; Hoppe-Tichy Torsten; Szabó Csaba; Karck Matthias; Sakurai Hiromu; Szabó Gábor
Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex.
Rejuvenation research 2008;11(5):945-56.
2008: Kiss Levente; Deitch Edwin A; Szabó Csaba
Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition.
Life sciences 2008;83(17-18):589-94.
2008: Simon Florian; Giudici Riccardo; Duy Cuong Nguyen; Schelzig Hubert; Oter Sükrü; Gröger Michael; Wachter Ulrich; Vogt Josef; Speit Günter; Szabó Csaba; Radermacher Peter; Calzia Enrico
Hemodynamic and metabolic effects of hydrogen sulfide during porcine ischemia/reperfusion injury.
Shock (Augusta, Ga.) 2008;30(4):359-64.
2008: Mabley Jon G; Pacher Pal; Murthy Kanneganti G K; Williams William; Southan Garry J; Salzman Andrew L; Szabo Csaba
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
The Journal of endocrinology 2008;198(3):581-9.
2008: Fink Ericka L; Lai Yichen; Zhang Xiaopeng; Janesko-Feldman Keri; Adelson P David; Szabó Csaba; Berger Rachel P; Sarnaik Ajit A; Kochanek Patrick M; Clark Robert S B
Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(9):1523-9.
2008: Hamahata Atsumori; Enkhbaatar Perenlei; Kraft Edward R; Lange Matthias; Leonard Scott W; Traber Maret G; Cox Robert A; Schmalstieg Frank C; Hawkins Hal K; Whorton Elbert B; Horvath Eszter M; Szabo Csaba; Traber Lillian D; Herndon David N; Traber Daniel L
gamma-Tocopherol nebulization by a lipid aerosolization device improves pulmonary function in sheep with burn and smoke inhalation injury.
Free radical biology & medicine 2008;45(4):425-33.
2008: Esechie Aimalohi; Kiss Levente; Olah Gabor; Horváth Eszter M; Hawkins Hal; Szabo Csaba; Traber Daniel L
Protective effect of hydrogen sulfide in a murine model of acute lung injury induced by combined burn and smoke inhalation.
Clinical science (London, England : 1979) 2008;115(3):91-7.
2008: Pyriochou Anastasia; Olah Gabor; Deitch Edwin A; Szabó Csaba; Papapetropoulos Andreas
Inhibition of angiogenesis by the poly(ADP-ribose) polymerase inhibitor PJ-34.
International journal of molecular medicine 2008;22(1):113-8.
2008: Pacher Pal; Szabo Csaba
Role of the peroxynitrite-poly(ADP-ribose) polymerase pathway in human disease.
The American journal of pathology 2008;173(1):2-13.
2008: Haddad Marianne; Beray-Berthat Virginie; Coqueran Bérard; Palmier Bruno; Szabo Csaba; Plotkine Michel; Margaill Isabelle
Reduction of hemorrhagic transformation by PJ34, a poly(ADP-ribose)polymerase inhibitor, after permanent focal cerebral ischemia in mice.
European journal of pharmacology 2008;588(1):52-7.
2008: Hegedus Csaba; Lakatos Petra; Oláh Gábor; Tóth Balázs I; Gergely Szabolcs; Szabó Eva; Bíró Tamás; Szabó Csaba; Virág László
Protein kinase C protects from DNA damage-induced necrotic cell death by inhibiting poly(ADP-ribose) polymerase-1.
FEBS letters 2008;582(12):1672-8.
2008: Sodha Neel R; Clements Richard T; Feng Jun; Liu Yuhong; Bianchi Cesario; Horvath Eszter M; Szabo Csaba; Sellke Frank W
The effects of therapeutic sulfide on myocardial apoptosis in response to ischemia-reperfusion injury.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2008;33(5):906-13.
2008: Gerö Domokos; Szabó Csaba
Poly(ADP-ribose) polymerase: a new therapeutic target?
Current opinion in anaesthesiology 2008;21(2):111-21.
2008: Westphal Martin; Enkhbaatar Perenlei; Schmalstieg Frank C; Kulp Gabriela A; Traber Lillian D; Morita Naoki; Cox Robert A; Hawkins Hal K; Westphal-Varghese Beena B; Rudloff Helen E; Maybauer Dirk M; Maybauer Marc O; Burke Ann S; Murakami Kazunori; Saunders Fiona; Horvath Eszter M; Szabo Csaba; Traber Daniel L
Neuronal nitric oxide synthase inhibition attenuates cardiopulmonary dysfunctions after combined burn and smoke inhalation injury in sheep.
Critical care medicine 2008;36(4):1196-204.
2008: McCourtie Anton S; Farivar Alexander S; Woolley Steven M; Merry Heather E; Wolf Patrick S; Szabo Csaba; Mulligan Michael S
Poly (ADP) ribose synthetase inhibition in alveolar macrophages undergoing hypoxia and reoxygenation.
Experimental and molecular pathology 2008;84(2):141-4.
2008: Lai Yichen; Chen Yaming; Watkins Simon C; Nathaniel Paula D; Guo Fengli; Kochanek Patrick M; Jenkins Larry W; Szabó Csaba; Clark Robert S B
Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury.
Journal of neurochemistry 2008;104(6):1700-11.
2008: Horváth Eszter M; Benko Rita; Gero Domonkos; Kiss Levente; Szabó Csaba
Treatment with insulin inhibits poly(ADP-ribose)polymerase activation in a rat model of endotoxemia.
Life sciences 2008;82(3-4):205-9.
2007: Szabó Csaba
Hydrogen sulphide and its therapeutic potential.
Nature reviews. Drug discovery 2007;6(11):917-35.
2007: Gerö Domokos; Módis Katalin; Nagy Nóra; Szoleczky Petra; Tóth Zoltán Dóri; Dormán György; Szabó Csaba
Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay.
International journal of molecular medicine 2007;20(5):749-61.
2007: Radovits Tamás; Zotkina Julia; Lin Li-Ni; Bömicke Timo; Arif Rawa; Gerö Domokos; Horváth Eszter M; Karck Matthias; Szabó Csaba; Szabó Gábor
Poly(ADP-Ribose) polymerase inhibition improves endothelial dysfunction induced by hypochlorite.
Experimental biology and medicine (Maywood, N.J.) 2007;232(9):1204-12.
2007: Szijártó Attila; Hahn Oszkár; Batmunkh Enkhjargal; Stangl Rita; Kiss András; Lotz Gábor; Schaff Zsuzsa; Váli László; Blázovics Anna; Gero Domokos; Szabó Csaba; Kupcsulik Péter; Harsányi László
Short-term alanyl-glutamine dipeptide pretreatment in liver ischemia-reperfusion model: effects on microcirculation and antioxidant status in rats.
Clinical nutrition (Edinburgh, Scotland) 2007;26(5):640-8.
2007: Elrod John W; Calvert John W; Morrison Joanna; Doeller Jeannette E; Kraus David W; Tao Ling; Jiao Xiangying; Scalia Rosario; Kiss Levente; Szabo Csaba; Kimura Hideo; Chow Chi-Wing; Lefer David J
Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(39):15560-5.
2007: Szijártó Attila; Batmunkh Enkhjargal; Hahn Oszkár; Mihály Zoltán; Kreiss Adám; Kiss András; Lotz Gábor; Schaff Zsuzsa; Váli László; Blázovics Anna; Geró Domokos; Szabó Csaba; Kupcsulik Péter
Effect of PJ-34 PARP-inhibitor on rat liver microcirculation and antioxidant status.
The Journal of surgical research 2007;142(1):72-80.
2007: Clark Robert S B; Vagni Vincent A; Nathaniel Paula D; Jenkins Larry W; Dixon C Edward; Szabó Csaba
Local administration of the poly(ADP-ribose) polymerase inhibitor INO-1001 prevents NAD+ depletion and improves water maze performance after traumatic brain injury in mice.
Journal of neurotrauma 2007;24(8):1399-405.
2007: Szabó Csaba; Ischiropoulos Harry; Radi Rafael
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics.
Nature reviews. Drug discovery 2007;6(8):662-80.
2007: Németh Zoltán H; Bleich David; Csóka Balázs; Pacher Pál; Mabley Jon G; Himer Leonóra; Vizi E Sylvester; Deitch Edwin A; Szabó Csaba; Cronstein Bruce N; Haskó György
Adenosine receptor activation ameliorates type 1 diabetes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(10):2379-88.
2007: Ihnat M A; Thorpe J E; Kamat C D; Szabó C; Green D E; Warnke L A; Lacza Z; Cselenyák A; Ross K; Shakir S; Piconi L; Kaltreider R C; Ceriello A
Reactive oxygen species mediate a cellular 'memory' of high glucose stress signalling.
Diabetologia 2007;50(7):1523-31.
2007: Radovits Tamás; Seres Leila; Gero Domokos; Berger Irina; Szabó Csaba; Karck Matthias; Szabó Gábor
Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction.
Experimental gerontology 2007;42(7):676-85.
2007: Lenzsér Gábor; Kis Béla; Snipes James A; Gáspár Tamás; Sándor Péter; Komjáti Katalin; Szabó Csaba; Busija David W
Contribution of poly(ADP-ribose) polymerase to postischemic blood-brain barrier damage in rats.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2007;27(7):1318-26.
2007: Mabley Jon G; Wallace Rebecca; Pacher Pál; Murphy Kanneganti; Szabó Csaba
Inhibition of poly(adenosine diphosphate-ribose) polymerase by the active form of vitamin D.
International journal of molecular medicine 2007;19(6):947-52.
2007: Radovits Tamás; Lin Li-ni; Zotkina Julia; Gero Domokos; Szabó Csaba; Karck Matthias; Szabó Gábor
Poly(ADP-ribose) polymerase inhibition improves endothelial dysfunction induced by reactive oxidant hydrogen peroxide in vitro.
European journal of pharmacology 2007;564(1-3):158-66.
2007: Bai Péter; Hegedus Csaba; Erdélyi Katalin; Szabó Eva; Bakondi Edina; Gergely Szabolcs; Szabó Csaba; Virág László
Protein tyrosine nitration and poly(ADP-ribose) polymerase activation in N-methyl-N-nitro-N-nitrosoguanidine-treated thymocytes: implication for cytotoxicity.
Toxicology letters 2007;170(3):203-13.
2007: Maier Christian; Scheuerle Angelika; Hauser Balázs; Schelzig Hubert; Szabó Csaba; Radermacher Peter; Kick Jochen
The selective poly(ADP)ribose-polymerase 1 inhibitor INO1001 reduces spinal cord injury during porcine aortic cross-clamping-induced ischemia/reperfusion injury.
Intensive care medicine 2007;33(5):845-50.
2007: Seabra A B; Pankotai E; Fehér M; Somlai A; Kiss L; Bíró L; Szabó C; Kollai M; de Oliveira M G; Lacza Z
S-nitrosoglutathione-containing hydrogel increases dermal blood flow in streptozotocin-induced diabetic rats.
The British journal of dermatology 2007;156(5):814-8.
2007: Quagliaro Lisa; Piconi Ludovica; Assaloni Roberta; Da Ros Roberto; Szabó Csaba; Ceriello Antonio
Primary role of superoxide anion generation in the cascade of events leading to endothelial dysfunction and damage in high glucose treated HUVEC.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2007;17(4):257-67.
2007: Horvath Eszter M; Szabó Csaba
Poly(ADP-ribose) polymerase as a drug target for cardiovascular disease and cancer: an update.
Drug news & perspectives 2007;20(3):171-81.
2007: Radovits Tamás; Seres Leila; Gero Domokos; Lin Li-ni; Beller Carsten J; Chen Song-He; Zotkina Julia; Berger Irina; Groves John T; Szabó Csaba; Szabó Gábor
The peroxynitrite decomposition catalyst FP15 improves ageing-associated cardiac and vascular dysfunction.
Mechanisms of ageing and development 2007;128(2):173-81.
2007: Csordás Attila; Pankotai Eszter; Snipes James A; Cselenyák Attila; Sárszegi Zsolt; Cziráki Attila; Gaszner Balázs; Papp Lajos; Benko Rita; Kiss Levente; Kovács Endre; Kollai Márk; Szabó Csaba; Busija David W; Lacza Zsombor
Human heart mitochondria do not produce physiologically relevant quantities of nitric oxide.
Life sciences 2007;80(7):633-7.
2007: Beller Carsten J; Horvath Eszter; Kosse Jens; Becker Alexander; Radovits Tamás; Krempien Robert; Berger Irina; Hagl Siegfried; Szabó Csaba; Szabó Gábor
Opposite effects of vascular irradiation on inflammatory response and apoptosis induction in the vessel wall layers via the peroxynitrite-poly(ADP-ribose) polymerase pathway.
Clinical research in cardiology : official journal of the German Cardiac Society 2007;96(1):8-16.
2007: Péter Szabolcs; Regöly-Mérei Andrea; Biró Lajos; Nagy Katalin; Arató Györgyi; Szabó Csaba; Vámos Adrienn; Martos Eva; Antal Magda
Lifestyle of school children: representative survey in metropolitan elementary schools. Part one.
Annals of nutrition & metabolism 2007;51(5):448-53.
2007: Pacher Pál; Szabó Csaba
Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors.
Cardiovascular drug reviews 2007;25(3):235-60.
2007: Szabó Csaba
Poly (ADP-ribose) polymerase activation and circulatory shock.
Novartis Foundation symposium 2007;280():92-103; discussion 103-7, 160-4.
2006: Kiss Levente; Chen Min; Gero Domokos; Módis Katalin; Lacza Zsombor; Szabó Csaba
Effects of 7-ketocholesterol on the activity of endothelial poly(ADP-ribose) polymerase and on endothelium-dependent relaxant function.
International journal of molecular medicine 2006;18(6):1113-7.
2006: Szabo Csaba; Pacher Pal; Swanson Raymond A
Novel modulators of poly(ADP-ribose) polymerase.
Trends in pharmacological sciences 2006;27(12):626-30.
2006: Szabó Csaba; Biser Alisha; Benko Rita; Böttinger Erwin; Suszták Katalin
Poly(ADP-ribose) polymerase inhibitors ameliorate nephropathy of type 2 diabetic Leprdb/db mice.
Diabetes 2006;55(11):3004-12.
2006: Lange Matthias; Szabo Csaba; Van Aken Hugo; Williams William; Traber Daniel L; Daudel Fritz; Bröking Katrin; Salzman Andrew L; Bone Hans-Georg; Westphal Martin
Short-term effects of glipizide (an adenosine triphosphate-sensitive potassium channel inhibitor) on cardiopulmonary hemodynamics and global oxygen transport in healthy and endotoxemic sheep.
Shock (Augusta, Ga.) 2006;26(5):516-21.
2006: Beller Carsten J; Kosse Jens; Radovits Tamás; Gerö Domokos; Krempien Robert; Gross Marie-Luise; Berger Irina; Hagl Siegfried; Szabó Csaba; Szabó Gábor
Poly(ADP-ribose) polymerase inhibition combined with irradiation: a dual treatment concept to prevent neointimal hyperplasia after endarterectomy.
International journal of radiation oncology, biology, physics 2006;66(3):867-75.
2006: Barth Eberhard; Radermacher Peter; Szabó Csaba
The world according to poly(ADP-ribose) polymerase (PARP)--update 2006.
Intensive care medicine 2006;32(10):1470-4.
2006: Tóth-Zsámboki Emese; Horváth Eszter; Vargova Katarina; Pankotai Eszter; Murthy Kanneganti; Zsengellér Zsuzsanna; Bárány Tamás; Pék Tamás; Fekete Katalin; Kiss Róbert Gábor; Préda István; Lacza Zsombor; Gerö Domokos; Szabó Csaba
Activation of poly(ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes.
Molecular medicine (Cambridge, Mass.) 2006;12(9-10):221-8.
2006: Haddad M; Rhinn H; Bloquel C; Coqueran B; Szabó C; Plotkine M; Scherman D; Margaill I
Anti-inflammatory effects of PJ34, a poly(ADP-ribose) polymerase inhibitor, in transient focal cerebral ischemia in mice.
British journal of pharmacology 2006;149(1):23-30.
2006: Beller Carsten J; Radovits Tamás; Seres Leila; Kosse Jens; Krempien Robert; Gross Marie-Luise; Penzel Roland; Berger Irina; Huber Peter E; Hagl Siegfried; Szabó Csaba; Szabó Gábor
Poly(ADP-ribose) polymerase inhibition reverses vascular dysfunction after gamma-irradiation.
International journal of radiation oncology, biology, physics 2006;65(5):1528-35.
2006: Molnár Andrea; Tóth Attila; Bagi Zsolt; Papp Zoltán; Edes István; Vaszily Miklós; Galajda Zoltán; Papp Julius Gy; Varró András; Szüts Viktória; Lacza Zsombor; Gerö Domokos; Szabó Csaba
Activation of the poly(ADP-ribose) polymerase pathway in human heart failure.
Molecular medicine (Cambridge, Mass.) 2006;12(7-8):143-52.
2006: Szabo Csaba
Hungary: academy needs more than internal reform.
Nature 2006;442(7101):353.
2006: Ramlawi Basel; Feng Jun; Mieno Shigetoshi; Szabo Csaba; Zsengeller Zsuzsanna; Clements Richard; Sodha Neel; Boodhwani Munir; Bianchi Cesario; Sellke Frank W
Indices of apoptosis activation after blood cardioplegia and cardiopulmonary bypass.
Circulation 2006;114(1 Suppl):I257-63.
2006: Szabó Gábor; Bährle Susanne; Sivanandam Vijayshankar; Stumpf Nicole; Gerö Domokos; Berger Irina; Beller Carsten; Hagl Siegfried; Szabó Csaba; Dengler Thomas J
Immunomodulatory effects of poly(ADP-ribose) polymerase inhibition contribute to improved cardiac function and survival during acute cardiac rejection.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006;25(7):794-804.
2006: Szabó Gábor; Stumpf Nicole; Radovits Tamás; Sonnenberg Karin; Gerö Domokos; Hagl Siegfried; Szabó Csaba; Bährle Susanne
Effects of inosine on reperfusion injury after heart transplantation.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2006;30(1):96-102.
2006: Szabó Gábor; Bährle Susanne; Stumpf Nicole; Szabó Csaba; Hagl Siegfried
Contractile dysfunction in experimental cardiac allograft rejection: role of the poly (ADP-ribose) polymerase pathway.
Transplant international : official journal of the European Society for Organ Transplantation 2006;19(6):506-13.
2006: Hauser Balázs; Gröger Michael; Ehrmann Ulrich; Albicini Maura; Brückner Uwe Bernd; Schelzig Hubert; Venkatesh Balasubramanian; Li Hongshan; Szabó Csaba; Speit Günter; Radermacher Peter; Kick Jochen
The parp-1 inhibitor ino-1001 facilitates hemodynamic stabilization without affecting DNA repair in porcine thoracic aortic cross-clamping-induced ischemia/reperfusion.
Shock (Augusta, Ga.) 2006;25(6):633-40.
2006: Ligeti László; Szenczi Orsolya; Prestia Christina M; Szabó Csaba; Horváth Katalin; Marcsek Zoltán L; van Stiphout Ruud G P M; van Riel Natal A W; Op den Buijs Jorn; Van der Vusse Ger J; Ivanics Tamás
Altered calcium handling is an early sign of streptozotocin-induced diabetic cardiomyopathy.
International journal of molecular medicine 2006;17(6):1035-43.
2006: Tóth Orsolya; Szabó Csaba; Kecskés Marianna; Pótó László; Nagy Agnes; Losonczy Hajna
In vitro effect of the potent poly(ADP-ribose) polymerase (PARP) inhibitor INO-1001 alone and in combination with aspirin, eptifibatide, tirofiban, enoxaparin or alteplase on haemostatic parameters.
Life sciences 2006;79(4):317-23.
2006: Beller Carsten J; Radovits Tamás; Kosse Jens; Gerö Domokos; Szabó Csaba; Szabó Gábor
Activation of the peroxynitrite-poly(adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: a new target to prevent restenosis after endarterectomy.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2006;43(4):824-30.
2006: Lacza Zsombor; Kozlov Andrey V; Pankotai Eszter; Csordás Attila; Wolf Gerald; Redl Heinz; Kollai Márk; Szabó Csaba; Busija David W; Horn Thomas F W
Mitochondria produce reactive nitrogen species via an arginine-independent pathway.
Free radical research 2006;40(4):369-78.
2006: Soriano Francisco G; Nogueira Antonio C; Caldini Elia G; Lins Marcelo H; Teixeira Ana C; Cappi Sylas B; Lotufo Paulo A; Bernik Márcia M S; Zsengellér Zsuzsanna; Chen Min; Szabó Csaba
Potential role of poly(adenosine 5'-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock.
Critical care medicine 2006;34(4):1073-9.
2006: Pacher Pál; Szabó Csaba
Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes.
Current opinion in pharmacology 2006;6(2):136-41.
2006: Horváth Eszter M; Lacza Zsombor; Csordás Attila; Szabó Csaba; Kollai Márk; Busija David W
Graft derived cells with double nuclei in the penumbral region of experimental brain trauma.
Neuroscience letters 2006;396(3):182-6.
2006: Paquette David W; Rosenberg Adam; Lohinai Zsolt; Southan Garry J; Williams Ray C; Offenbacher Steven; Szabó Csaba
Inhibition of experimental gingivitis in beagle dogs with topical mercaptoalkylguanidines.
Journal of periodontology 2006;77(3):385-91.
2006: Pacher Pál; Nivorozhkin Alex; Szabó Csaba
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol.
Pharmacological reviews 2006;58(1):87-114.
2006: Ye Diana Z; Tai Mei-Hui; Linning Katrina D; Szabo Csaba; Olson L Karl
MafA expression and insulin promoter activity are induced by nicotinamide and related compounds in INS-1 pancreatic beta-cells.
Diabetes 2006;55(3):742-50.
2006: Szabó Csaba
Poly(ADP-ribose) polymerase activation by reactive nitrogen species--relevance for the pathogenesis of inflammation.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(2):169-79.
2006: Lacza Zsombor; Pankotai Eszter; Csordás Attila; Gero Domokos; Kiss Levente; Horváth Eszter M; Kollai Márk; Busija David W; Szabó Csaba
Mitochondrial NO and reactive nitrogen species production: does mtNOS exist?
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;14(2):162-8.
2006: Pacher Pál; Liaudet Lucas; Mabley Jon G; Cziráki Attila; Haskó György; Szabó Csaba
Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure.
International journal of molecular medicine 2006;17(2):369-75.
2006: Gero Domokos; Szabó Csaba
Role of the peroxynitrite-poly (ADP-ribose) polymerase pathway in the pathogenesis of liver injury.
Current pharmaceutical design 2006;12(23):2903-10.
2005: Szabó Csaba
Mechanisms of cell necrosis.
Critical care medicine 2005;33(12 Suppl):S530-4.
2005: Lobo Suzana M; Orrico Susana R Perez; Queiroz Márcio M; Cunrath Geni S; Chibeni Gisela S A; Contrin Ligia M; Cury Patricia M; Burdmann Emanuel de Almeida; de Oliveira Machado Antonia M; Togni Paulo; De Backer Daniel; Preiser Jean-Charles; Szabó Czaba; Vincent Jean-Louis
Pneumonia-induced sepsis and gut injury: effects of a poly-(ADP-ribose) polymerase inhibitor.
The Journal of surgical research 2005;129(2):292-7.
2005: Pacher Pál; Szabó Csaba
Role of poly(ADP-ribose) polymerase-1 activation in the pathogenesis of diabetic complications: endothelial dysfunction, as a common underlying theme.
Antioxidants & redox signaling 2005;7(11-12):1568-80.
2005: Mangino Martin J; Ametani Mary S; Gilligan Barbara J; Szabo Csaba; Brounts Lionel; Southard James H
Role of peroxynitrite anion in renal hypothermic preservation injury.
Transplantation 2005;80(10):1455-60.
2005: Kendirci Muammer; Zsengellér Zsuzsanna; Bivalacqua Trinity J; Gur Serap; Usta Mustafa F; Chen Min; Szabó Csaba; Hellstrom Wayne J G
Poly(Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury.
The Journal of urology 2005;174(5):2054-9.
2005: Mabley Jon G; Horváth Eszter M; Murthy Kanneganti G K; Zsengellér Zsuzsanna; Vaslin Anne; Benko Rita; Kollai Márk; Szabó Csaba
Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.
The Journal of pharmacology and experimental therapeutics 2005;315(2):812-20.
2005: Lacza Zsombor; Horváth Eszter M; Pankotai Eszter; Csordás Attila; Kollai Márk; Szabó Csaba; Busija David W
The novel red-fluorescent probe DAR-4M measures reactive nitrogen species rather than NO.
Journal of pharmacological and toxicological methods 2005;52(3):335-40.
2005: Cheng C Lynn; Johnson Stewart P; Keir Stephen T; Quinn Jennifer A; Ali-Osman Francis; Szabo Csaba; Li Hongshan; Salzman Andrew L; Dolan M Eileen; Modrich Paul; Bigner Darell D; Friedman Henry S
Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
Molecular cancer therapeutics 2005;4(9):1364-8.
2005: Farivar Alexander S; McCourtie Anton S; MacKinnon-Patterson Brendan C; Woolley Steven M; Barnes Andrew D; Chen Min; Jagtap Prakash; Szabó Csaba; Salerno Christopher T; Mulligan Michael S
Poly (ADP) ribose polymerase inhibition improves rat cardiac allograft survival.
The Annals of thoracic surgery 2005;80(3):950-6.
2005: Erdèlyi Katalin; Kiss Andrea; Bakondi Edina; Bai Péter; Szabó Csaba; Gergely Pál; Erdödi Ferenc; Virag László
Gallotannin inhibits the expression of chemokines and inflammatory cytokines in A549 cells.
Molecular pharmacology 2005;68(3):895-904.
2005: Jagtap Prakash G; Baloglu Erkan; Southan Garry J; Mabley Jon G; Li Hongshan; Zhou Jing; van Duzer John; Salzman Andrew L; Szabó Csaba
Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone.
Journal of medicinal chemistry 2005;48(16):5100-3.
2005: Szabó Csaba
Pharmacological inhibition of poly(ADP-ribose) polymerase in cardiovascular disorders: future directions.
Current vascular pharmacology 2005;3(3):301-3.
2005: Neville Lewis F; Barnea Yoav; Hammer-Munz Orly; Gur Eyal; Kuzmenko Boris; Kahel-Raifer Hamutal; Eren Rachel; Elkeles Adi; Murthy Kanneganti G K; Szabó Csaba; Salzman Andrew L; Dagan Shlomo; Carmeli Yehuda; Navon-Venezia Shiri
Antibodies raised against N'-terminal Pseudomonas aeruginosa flagellin prevent mortality in lethal murine models of infection.
International journal of molecular medicine 2005;16(1):165-71.
2005: Graziani Grazia; Szabó Csaba
Clinical perspectives of PARP inhibitors.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):109-18.
2005: Szabó Csaba
Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):60-71.
2005: Szabó Csaba
Cardioprotective effects of poly(ADP-ribose) polymerase inhibition.
Pharmacological research : the official journal of the Italian Pharmacological Society 2005;52(1):34-43.
2005: Pieper Galen M; Nilakantan Vani; Chen Min; Zhou Jing; Khanna Ashwani K; Henderson James D; Johnson Christopher P; Roza Allan M; Szabó Csaba
Protective mechanisms of a metalloporphyrinic peroxynitrite decomposition catalyst, WW85, in rat cardiac transplants.
The Journal of pharmacology and experimental therapeutics 2005;314(1):53-60.
2005: Pacher Pal; Schulz Richard; Liaudet Lucas; Szabó Csaba
Nitrosative stress and pharmacological modulation of heart failure.
Trends in pharmacological sciences 2005;26(6):302-10.
2005: Goldfarb Roy D; Szabo Csaba
Free radical scavenging as a therapeutic strategy for bacteremia.
Critical care medicine 2005;33(5):1163-6.
2005: Jagtap Prakash; Szabó Csaba
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors.
Nature reviews. Drug discovery 2005;4(5):421-40.
2005: Li Fei; Drel Viktor R; Szabó Csaba; Stevens Martin J; Obrosova Irina G
Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.
Diabetes 2005;54(5):1514-22.
2005: Suzuki Yoshihiko; Lu Qi; Xu Da-Zhong; Szabó Csaba; Haskó György; Deitch Edwin A
Na+,K+-ATPase activity is inhibited in cultured intestinal epithelial cells by endotoxin or nitric oxide.
International journal of molecular medicine 2005;15(5):871-7.
2005: Erdélyi K; Bakondi E; Gergely P; Szabó C; Virág L
Pathophysiologic role of oxidative stress-induced poly(ADP-ribose) polymerase-1 activation: focus on cell death and transcriptional regulation.
Cellular and molecular life sciences : CMLS 2005;62(7-8):751-9.
2005: Komjáti Katalin; Besson Valerie C; Szabó Csaba
Poly (adp-ribose) polymerase inhibitors as potential therapeutic agents in stroke and neurotrauma.
Current drug targets. CNS and neurological disorders 2005;4(2):179-94.
2005: Jagtap Prakash G; Baloglu Erkan; Southan Garry; Williams William; Roy Aloka; Nivorozhkin Alexander; Landrau Nelson; Desisto Kevin; Salzman Andrew L; Szabó Csaba
Facile and convenient syntheses of 6,11-dihydro-5H-indeno[1,2-c]isoquinolin- 5-ones and 6,11-dihydro-5H-indolo[3,2-c]isoquinolin-5-one.
Organic letters 2005;7(9):1753-6.
2005: Besson Valérie C; Zsengellér Zsuzsanna; Plotkine Michel; Szabó Csaba; Marchand-Verrecchia Catherine
Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat.
Brain research 2005;1041(2):149-56.
2005: Kiss Levente; Szabó Csaba
The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity.
Memórias do Instituto Oswaldo Cruz 2005;100 Suppl 1():29-37.
2005: Crocker Ian P; Kenny Louise C; Thornton Wayne A; Szabo Csaba; Baker Philip N
Excessive stimulation of poly(ADP-ribosyl)ation contributes to endothelial dysfunction in pre-eclampsia.
British journal of pharmacology 2005;144(6):772-80.
2005: Bjertnaes Lars J; McGuire Roy; Jodoin Jeffery; Salzman Andrew L; Traber Lillian D; Passerini Daniel J; Smith Daniel J; Szabo Csaba; Traber Daniel L
Nebulized nitric oxide/nucleophile adduct reduces pulmonary vascular resistance in mechanically ventilated septicemic sheep.
Critical care medicine 2005;33(3):616-22.
2005: Szenczi Orsolya; Kemecsei Péter; Holthuijsen Max F J; van Riel Natal A W; van der Vusse Ger J; Pacher Pál; Szabó Csaba; Kollai Márk; Ligeti László; Ivanics Tamás
Poly(ADP-ribose) polymerase regulates myocardial calcium handling in doxorubicin-induced heart failure.
Biochemical pharmacology 2005;69(5):725-32.
2005: Obrosova Irina G; Mabley Jon G; Zsengellér Zsuzsanna; Charniauskaya Tamara; Abatan Omorodola I; Groves John T; Szabó Csaba
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):401-3.
2005: Xiao Chun-Yang; Chen Min; Zsengellér Zsuzsanna; Li Hongshan; Kiss Levente; Kollai Márk; Szabó Csaba
Poly(ADP-Ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure.
The Journal of pharmacology and experimental therapeutics 2005;312(3):891-8.
2005: Szabó Gábor; Soós Pál; Heger Ulrike; Flechtenmacher Christa; Bährle Susanne; Zsengellér Zsuzsanna; Szabó Csaba; Hagl Siegfried
Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2005;27(2):226-34.
2005: Mabley Jon G; Pacher Pál; Deb Amitabha; Wallace Rebecca; Elder Rhoderick H; Szabó Csaba
Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(2):290-2.
2005: Casey Patrick J; Black James H; Szabo Csaba; Frosch Matthew; Albadawi Hassan; Chen Min; Cambria Richard P; Watkins Michael T
Poly(adenosine diphosphate ribose) polymerase inhibition modulates spinal cord dysfunction after thoracoabdominal aortic ischemia-reperfusion.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 2005;41(1):99-107.
2005: op den Buijs Jorn; Miklós Zsuzsanna; van Riel Natal A W; Prestia Christina M; Szenczi Orsolya; Tóth András; Van der Vusse Ger J; Szabó Csaba; Ligeti László; Ivanics Tamás
beta-Adrenergic activation reveals impaired cardiac calcium handling at early stage of diabetes.
Life sciences 2005;76(10):1083-98.
2005: Obrosova Irina G; Pacher Pal; Szabó Csaba; Zsengeller Zsuzsanna; Hirooka Hiroko; Stevens Martin J; Yorek Mark A
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.
Diabetes 2005;54(1):234-42.
2005: Pacher Pál; Obrosova Irina G; Mabley Jon G; Szabó Csaba
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.
Current medicinal chemistry 2005;12(3):267-75.
2004: Szabó Gábor; Soós Pál; Mandera Susanne; Heger Ulrike; Flechtenmacher Christa; Seres Leila; Zsengellér Zsuzsanna; Sack Falk-Udo; Szabó Csaba; Hagl Siegfried
Mesenteric injury after cardiopulmonary bypass: role of poly(adenosine 5'-diphosphate-ribose) polymerase.
Critical care medicine 2004;32(12):2392-7.
2004: Szabó G; Seres L; Soós P; Flechtenmacher C; Zsengellér Z; Sack F-U; Szabó C; Hagl S
Poly-ADP-ribose polymerase inhibition reduces mesenteric injury after cardiopulmonary bypass.
The Thoracic and cardiovascular surgeon 2004;52(6):338-43.
2004: Murthy K G K; Szabó C; Salzman A L
Cytokines stimulate expression of inducible nitric oxide synthase in DLD-1 human adenocarcinoma cells by activating poly(A) polymerase.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004;53(11):604-8.
2004: Woolley Steven M; Farivar Alexander S; Naidu Babu V; Salzman Andrew; Szabo Csaba; Thomas Robert; Fraga Charles; Mulligan Michael S
Role of poly (ADP) ribose synthetase in lung ischemia-reperfusion injury.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2004;23(11):1290-6.
2004: Zheng Ling; Szabó Csaba; Kern Timothy S
Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB.
Diabetes 2004;53(11):2960-7.
2004: Pacher Pál; Mabley Jon G; Liaudet Lucas; Evgenov Oleg V; Marton Anita; Haskó György; Kollai Márk; Szabó Csaba
Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure.
American journal of physiology. Heart and circulatory physiology 2004;287(5):H2132-7.
2004: Pacher Pál; Vaslin Anne; Benko Rita; Mabley Jon G; Liaudet Lucas; Haskó György; Marton Anita; Bátkai Sándor; Kollai Márk; Szabó Csaba
A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging.
The Journal of pharmacology and experimental therapeutics 2004;311(2):485-91.
2004: Maybauer Dirk M; Salsbury John R; Westphal Martin; Maybauer Marc O; Salzman Andrew L; Szabó Csaba; Westphal-Varghese Beena B; Traber Lillian D; Traber Daniel L
The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock.
Shock (Augusta, Ga.) 2004;22(4):387-91.
2004: Antal Magda; Regöly-Mérei Andrea; Nagy Katalin; Greiner Erika; Biró Lajos; Domonkos Andrea; Balajti Anikó; Szórád Ildikó; Szabó Csaba; Mozsáry Erzsébet
Representative study for the evaluation of age- and gender-specific anthropometric parameters and blood pressure in an adolescent Hungarian population.
Annals of nutrition & metabolism 2004;48(5):307-13.
2004: Scott Gwen S; Szabó Csaba; Hooper D Craig
Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro.
Journal of neurotrauma 2004;21(9):1255-63.
2004: Chen Min; Zsengellér Zsuzsanna; Xiao Chun-Yang; Szabó Csaba
Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1.
Cardiovascular research 2004;63(4):682-8.
2004: Scott Gwen S; Kean Rhonda B; Mikheeva Tatiana; Fabis Marzena J; Mabley Jon G; Szabó Csaba; Hooper D Craig
The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1053-61.
2004: Farivar Alexander S; Woolley Steven M; Naidu Babu V; Fraga Charles H; Byrne Karen; Thomas Robert; Salzman Andrew L; Szabo Csaba S; Mulligan Michael S
Poly (ADP) ribose synthetase inhibition reduces obliterative airway disease in rat tracheal allografts.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2004;23(8):993-1002.
2004: Piconi L; Quagliaro L; Da Ros R; Assaloni R; Giugliano D; Esposito K; Szabó C; Ceriello A
Intermittent high glucose enhances ICAM-1, VCAM-1, E-selectin and interleukin-6 expression in human umbilical endothelial cells in culture: the role of poly(ADP-ribose) polymerase.
Journal of thrombosis and haemostasis : JTH 2004;2(8):1453-9.
2004: Lacza Zsombor; Horn Thomas F W; Snipes James A; Zhang Jie; Roychowdhury Sanjoy; Horváth Eszter M; Figueroa Jorge P; Kollai Márk; Szabó Csaba; Busija David W
Lack of mitochondrial nitric oxide production in the mouse brain.
Journal of neurochemistry 2004;90(4):942-51.
2004: Xiao Chun-Yang; Chen Min; Zsengellér Zsuzsanna; Szabó Csaba
Poly(ADP-ribose) polymerase contributes to the development of myocardial infarction in diabetic rats and regulates the nuclear translocation of apoptosis-inducing factor.
The Journal of pharmacology and experimental therapeutics 2004;310(2):498-504.
2004: Sugawara R; Hikichi T; Kitaya N; Mori F; Nagaoka T; Yoshida A; Szabo C
Peroxynitrite decomposition catalyst, FP15, and poly(ADP-ribose) polymerase inhibitor, PJ34, inhibit leukocyte entrapment in the retinal microcirculation of diabetic rats.
Current eye research 2004;29(1):11-6.
2004: Benkö Rita; Pacher Pál; Vaslin Anne; Kollai Márk; Szabó Csaba
Restoration of the endothelial function in the aortic rings of apolipoprotein E deficient mice by pharmacological inhibition of the nuclear enzyme poly(ADP-ribose) polymerase.
Life sciences 2004;75(10):1255-61.
2004: Obrosova Irina G; Minchenko Alexander G; Frank Robert N; Seigel Gail M; Zsengeller Zsuzsanna; Pacher Pál; Stevens Martin J; Szabó Csaba
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.
International journal of molecular medicine 2004;14(1):55-64.
2004: Németh Zoltán H; Deitch Edwin A; Davidson Marson T; Szabó Csaba; Vizi E Sylvester; Haskó György
Disruption of the actin cytoskeleton results in nuclear factor-kappaB activation and inflammatory mediator production in cultured human intestinal epithelial cells.
Journal of cellular physiology 2004;200(1):71-81.
2004: Farivar Alexander S; Woolley Steven M; Fraga Charles H; Thomas Robert; Salzman Andrew L; Szabo Csaba; Mulligan Michael S
Intratracheal poly (ADP) ribose synthetase inhibition ameliorates lung ischemia reperfusion injury.
The Annals of thoracic surgery 2004;77(6):1938-43.
2004: Szabó Gábor; Soós Pál; Mandera Susanne; Heger Ulrike; Flechtenmacher Christa; Bährle Susanne; Seres Leila; Cziráki Attila; Gries Andre; Zsengellér Zsuszanna; Vahl Christian F; Hagl Siegfried; Szabó Csaba
INO-1001 a novel poly(ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation.
Shock (Augusta, Ga.) 2004;21(5):426-32.
2004: Szabó Gábor; Soós Pál; Bährle Susanne; Zsengellér Zsuzsanna; Flechtenmacher Christa; Hagl Siegfried; Szabó Csaba
Role of poly(ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2004;25(5):825-32.
2004: Mangino Martin J; Ametani Mary; Szabó Csaba; Southard James H
Poly(ADP-ribose) polymerase and renal hypothermic preservation injury.
American journal of physiology. Renal physiology 2004;286(5):F838-47.
2004: Li F; Szabó C; Pacher P; Southan G J; Abatan O I; Charniauskaya T; Stevens M J; Obrosova I G
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.
Diabetologia 2004;47(4):710-7.
2004: Mabley Jon G; Pacher Pál; Bai Peter; Wallace Rebecca; Goonesekera Sunali; Virag Laszlo; Southan Garry J; Szabó Csaba
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways.
Mutation research 2004;548(1-2):107-16.
2004: Brock William A; Milas Luka; Bergh Sherry; Lo Ruth; Szabó Csaba; Mason Kathy A
Radiosensitization of human and rodent cell lines by INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase.
Cancer letters 2004;205(2):155-60.
2004: Mabley Jon G; Southan Gary J; Salzman Andrew L; Szabó Csaba
The combined inducible nitric oxide synthase inhibitor and free radical scavenger guanidinoethyldisulfide prevents multiple low-dose streptozotocin-induced diabetes in vivo and interleukin-1beta-induced suppression of islet insulin secretion in vitro.
Pancreas 2004;28(2):E39-44.
2004: Haskó György; Sitkovsky Michail V; Szabó Csaba
Immunomodulatory and neuroprotective effects of inosine.
Trends in pharmacological sciences 2004;25(3):152-7.
2004: Jagtap Prakash G; Chen Zhiyu; Szabó Csaba; Klotz Karl-Norbert
2-(N-acyl) and 2-N-acyl-N(6)-substituted analogues of adenosine and their affinity at the human adenosine receptors.
Bioorganic & medicinal chemistry letters 2004;14(6):1495-8.
2004: Obrosova Irina G; Li Fei; Abatan Omorodola I; Forsell Mark A; Komjáti Katalin; Pacher Pal; Szabó Csaba; Stevens Martin J
Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.
Diabetes 2004;53(3):711-20.
2004: Bakondi Edina; Bai Péter; Erdélyi Katalin; Szabó Csaba; Gergely Pál; Virág László
Cytoprotective effect of gallotannin in oxidatively stressed HaCaT keratinocytes: the role of poly(ADP-ribose) metabolism.
Experimental dermatology 2004;13(3):170-8.
2004: Virág László; Bai Péter; Bak István; Pacher Pál; Mabley Jon G; Liaudet Lucas; Bakondi Edina; Gergely Pál; Kollai Márk; Szabó Csaba
Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
Medical science monitor : international medical journal of experimental and clinical research 2004;10(3):BR77-83.
2004: Murthy Kanneganti G K; Xiao Chun-Yang; Mabley Jon G; Chen Min; Szabó Csaba
Activation of poly(ADP-ribose) polymerase in circulating leukocytes during myocardial infarction.
Shock (Augusta, Ga.) 2004;21(3):230-4.
2004: Komjáti Katalin; Mabley John G; Virág László; Southan Garry J; Salzman Andrew L; Szabó Csaba
Poly(ADP-ribose) polymerase inhibition protect neurons and the white matter and regulates the translocation of apoptosis-inducing factor in stroke.
International journal of molecular medicine 2004;13(3):373-82.
2004: Szabó Gábor; Liaudet Lucas; Hagl Siegfried; Szabó Csaba
Poly(ADP-ribose) polymerase activation in the reperfused myocardium.
Cardiovascular research 2004;61(3):471-80.
2004: Murakami Kazunori; Enkhbaatar Perenlei; Shimoda Katsumi; Cox Robert A; Burke Ann S; Hawkins Hal K; Traber Lillian D; Schmalstieg Frank C; Salzman Andrew L; Mabley Jon G; Komjáti Katalin; Pacher Pál; Zsengellér Zsuzsanna; Szabó Csaba; Traber Daniel L
Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis.
Shock (Augusta, Ga.) 2004;21(2):126-33.
2004: Németh Zoltán H; Wong Hector R; Odoms Kelli; Deitch Edwin A; Szabó Csaba; Vizi E Sylvester; Haskó György
Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells.
Molecular pharmacology 2004;65(2):342-9.
2004: Bai Péter; Mabley Jon G; Liaudet Lucas; Virág László; Szabó Csaba; Pacher Pál
Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity.
Oncology reports 2004;11(2):505-8.
2004: Murthy Kanneganti G K; Deb Amitabha; Goonesekera Sunali; Szabó Csaba; Salzman Andrew L
Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro.
The Journal of biological chemistry 2004;279(7):5667-75.
2004: Szabó Csaba; Pacher Pál; Zsengellér Zsuzsanna; Vaslin Anne; Komjáti Katalin; Benkö Rita; Chen Min; Mabley Jon G; Kollai Márk
Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.
Molecular medicine (Cambridge, Mass.) 2004;10(1-6):28-35.
2004: Jagtap Prakash G; Southan Garry J; Baloglu Erkan; Ram Siya; Mabley Jon G; Marton Anita; Salzman Andrew; Szabó Csaba
The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).
Bioorganic & medicinal chemistry letters 2004;14(1):81-5.
2003: Pacher P; Mabley J G; Liaudet L; Evgenov O V; Southan G J; Abdelkarim G E; Szabó C; Salzman A L
Topical administration of a novel nitric oxide donor, linear polyethylenimine-nitric oxide/nucleophile adduct (DS1), selectively increases vaginal blood flow in anesthetized rats.
International journal of impotence research 2003;15(6):461-4.
2003: Németh Zoltán H; Leibovich S Joseph; Deitch Edwin A; Sperlágh Beáta; Virág László; Vizi E Sylvester; Szabó Csaba; Haskó György
Adenosine stimulates CREB activation in macrophages via a p38 MAPK-mediated mechanism.
Biochemical and biophysical research communications 2003;312(4):883-8.
2003: Lacza Zsombor; Snipes James A; Kis Béla; Szabó Csaba; Grover Gary; Busija David W
Investigation of the subunit composition and the pharmacology of the mitochondrial ATP-dependent K+ channel in the brain.
Brain research 2003;994(1):27-36.
2003: Lohinai Z; Mabley J G; Fehér E; Marton A; Komjáti K; Szabó C
Role of the activation of the nuclear enzyme poly(ADP-ribose) polymerase in the pathogenesis of periodontitis.
Journal of dental research 2003;82(12):987-92.
2003: Lacza Zsombor; Snipes James A; Zhang Jie; Horváth Eszter M; Figueroa Jorge P; Szabó Csaba; Busija David W
Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS.
Free radical biology & medicine 2003;35(10):1217-28.
2003: Lacza Zsombor; Snipes James A; Miller Allison W; Szabó Csaba; Grover Gary; Busija David W
Heart mitochondria contain functional ATP-dependent K+ channels.
Journal of molecular and cellular cardiology 2003;35(11):1339-47.
2003: Evgenov Oleg V; Pacher Pál; Williams William; Evgenov Natalia V; Mabley Jon G; Cicila James; Sikó Zsombor B; Salzman Andrew L; Szabó Csaba
Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats.
Critical care medicine 2003;31(10):2429-36.
2003: Du Xueliang; Matsumura Takeshi; Edelstein Diane; Rossetti Luciano; Zsengellér Zsuzsanna; Szabó Csaba; Brownlee Michael
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells.
The Journal of clinical investigation 2003;112(7):1049-57.
2003: Huang Hong; McIntosh Jane L; Fang Lanyan; Szabo Csaba; Hoyt Dale G
Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion.
International journal of molecular medicine 2003;12(4):533-40.
2003: Szabó Gábor; Buhmann Volker; Andrási Terézia; Stumpf Nicole; Bährle Susanne; Kékesi Violetta; Hagl Siegfried; Szabó Csaba; Juhász-Nagy Alexander
Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest.
The Journal of thoracic and cardiovascular surgery 2003;126(3):651-8.
2003: Németh Zoltán H; Leibovich S Joseph; Deitch Edwin A; Vizi E Sylvester; Szabó Csaba; Hasko Gyorgy
cDNA microarray analysis reveals a nuclear factor-kappaB-independent regulation of macrophage function by adenosine.
The Journal of pharmacology and experimental therapeutics 2003;306(3):1042-9.
2003: Khan Tanveer A; Ruel Marc; Bianchi Cesario; Voisine Pierre; Komjáti Katalin; Szabo Csaba; Sellke Frank W
Poly(ADP-ribose) polymerase inhibition improves postischemic myocardial function after cardioplegia-cardiopulmonary bypass.
Journal of the American College of Surgeons 2003;197(2):270-7.
2003: Lacza Zsombor; Horváth Eszter M; Komjáti Katalin; Hortobágyi Tibor; Szabó Csaba; Busija David W
PARP inhibition improves the effectiveness of neural stem cell transplantation in experimental brain trauma.
International journal of molecular medicine 2003;12(2):153-9.
2003: Naidu Babu V; Farivar Alexander S; Woolley Steven M; Fraga Charles; Salzman Andrew L; Szabo Csaba; Groves John T; Mulligan Michael S
Enhanced peroxynitrite decomposition protects against experimental obliterative bronchiolitis.
Experimental and molecular pathology 2003;75(1):12-7.
2003: Minchenko Alexander G; Stevens Martin J; White Lauren; Abatan Omorodola I; Komjáti Katalin; Pacher Pal; Szabó Csaba; Obrosova Irina G
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1514-6.
2003: Naidu Babu V; Fraga Charles; Salzman Andrew L; Szabo Csaba; Verrier Edward D; Mulligan Michael S
Critical role of reactive nitrogen species in lung ischemia-reperfusion injury.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2003;22(7):784-93.
2003: Bakondi Edina; Gönczi Mónika; Szabó Eva; Bai Péter; Pacher Pál; Gergely Pál; Kovács László; Hunyadi János; Szabó Csaba; Csernoch László; Virág László
Role of intracellular calcium mobilization and cell-density-dependent signaling in oxidative-stress-induced cytotoxicity in HaCaT keratinocytes.
The Journal of investigative dermatology 2003;121(1):88-95.
2003: Suarez-Pinzon Wilma L; Mabley Jon G; Power Robert; Szabó Csaba; Rabinovitch Alex
Poly (ADP-ribose) polymerase inhibition prevents spontaneous and recurrent autoimmune diabetes in NOD mice by inducing apoptosis of islet-infiltrating leukocytes.
Diabetes 2003;52(7):1683-8.
2003: Shimoda Katsumi; Murakami Kazunori; Enkhbaatar Perenlei; Traber Lillian D; Cox Robert A; Hawkins Hal K; Schmalstieg Frank C; Komjati Katalin; Mabley Jon G; Szabo Csaba; Salzman Andrew L; Traber Daniel L
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep.
American journal of physiology. Lung cellular and molecular physiology 2003;285(1):L240-9.
2003: Szabó Csaba
Nicotinamide: a jack of all trades (but master of none?).
Intensive care medicine 2003;29(6):863-6.
2003: Iványi Zsolt; Hauser Balázs; Pittner Antje; Asfar Pierre; Vassilev Damian; Nalos Marek; Altherr Jürgen; Brückner Uwe Bernd; Szabó Csaba; Radermacher Peter; Fröba Gebhard
Systemic and hepatosplanchnic hemodynamic and metabolic effects of the PARP inhibitor PJ34 during hyperdynamic porcine endotoxemia.
Shock (Augusta, Ga.) 2003;19(5):415-21.
2003: Satchell Margaret A; Zhang Xiaopeng; Kochanek Patrick M; Dixon C Edward; Jenkins Larry W; Melick John; Szabó Csaba; Clark Robert S B
A dual role for poly-ADP-ribosylation in spatial memory acquisition after traumatic brain injury in mice involving NAD+ depletion and ribosylation of 14-3-3gamma.
Journal of neurochemistry 2003;85(3):697-708.
2003: Du Lina; Zhang Xiaopeng; Han Yong Y; Burke Nancy A; Kochanek Patrick M; Watkins Simon C; Graham Steven H; Carcillo Joseph A; Szabó Csaba; Clark Robert S B
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.
The Journal of biological chemistry 2003;278(20):18426-33.
2003: Veres Balazs; Gallyas Ferenc; Varbiro Gabor; Berente Zoltan; Osz Erzsebet; Szekeres Gyorgy; Szabo Csaba; Sumegi Balazs
Decrease of the inflammatory response and induction of the Akt/protein kinase B pathway by poly-(ADP-ribose) polymerase 1 inhibitor in endotoxin-induced septic shock.
Biochemical pharmacology 2003;65(8):1373-82.
2003: Mabley Jon; Soriano Francisco; Pacher Pál; Haskó György; Marton Anita; Wallace Rebecca; Salzman Andrew; Szabó Csaba
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis.
European journal of pharmacology 2003;466(3):323-9.
2003: Virág László; Szabó Eva; Gergely Pál; Szabó Csaba
Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention.
Toxicology letters 2003;140-141():113-24.
2003: Szabó Csaba
Multiple pathways of peroxynitrite cytotoxicity.
Toxicology letters 2003;140-141():105-12.
2003: Liaudet Lucas; Szabó Gábor; Szabó Csaba
Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite-poly(ADP-ribose) polymerase connection.
Coronary artery disease 2003;14(2):115-22.
2003: Mabley Jon G; Rabinovitch Alex; Suarez-Pinzon Wilma; Haskó György; Pacher Pál; Power Robert; Southan Gary; Salzman Andrew; Szabó Csaba
Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.
Molecular medicine (Cambridge, Mass.) 2003;9(3-4):96-104.
2003: Pacher Pál; Liaudet Lucas; Bai Péter; Mabley Jon G; Kaminski Pawel M; Virág László; Deb Amitabha; Szabó Eva; Ungvári Zoltán; Wolin Michael S; Groves John T; Szabó Csaba
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction.
Circulation 2003;107(6):896-904.
2003: Liaudet Lucas; Szabó Csaba; Evgenov Oleg V; Murthy Kanneganti G; Pacher Pál; Virág László; Mabley Jon G; Marton Anita; Soriano Francisco G; Kirov Mikhail Y; Bjertnaes Lars J; Salzman Andrew L
Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis.
Shock (Augusta, Ga.) 2003;19(2):131-7.
2003: Southan Garry J; Szabó Csaba
Poly(ADP-ribose) polymerase inhibitors.
Current medicinal chemistry 2003;10(4):321-40.
2003: Antal Magda; Regöly-Mérei Andrea; Nagy Katalin; Greiner Erika; Biró Lajos; Domonkos Andrea; Balajti Anikó; Szabó Csaba; Mozsáry Erzsébet
[Cut-off values for the diagnosis of obesity and hypertension based on epidemiologic measurements in Hungarian youth]
Orvosi hetilap 2003;144(1):13-9.
2003: Szabó Csaba
Role of flagellin in the pathogenesis of shock and acute respiratory distress syndrome: therapeutic opportunities.
Critical care medicine 2003;31(1 Suppl):S39-45.
2003: Scott Gwen S; Virág Laszlo; Szabó Csaba; Hooper D Craig
Peroxynitrite-induced oligodendrocyte toxicity is not dependent on poly(ADP-ribose) polymerase activation.
Glia 2003;41(2):105-16.
2003: Németh Zoltán H; Deitch Edwin A; Szabó Csaba; Haskó György
Pyrrolidinedithiocarbamate inhibits NF-kappaB activation and IL-8 production in intestinal epithelial cells.
Immunology letters 2003;85(1):41-6.
2003: Mabley J G; Pacher P; Liaudet L; Soriano F G; Haskó G; Marton A; Szabo C; Salzman A L
Inosine reduces inflammation and improves survival in a murine model of colitis.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(1):G138-44.
2003: Szabó Cs
Pathophysiological aspects of cellular pyridine nucleotide metabolism: focus on the vascular endothelium. Review.
Acta physiologica Hungarica 2003;90(3):175-93.
2002: Kirov Mikhail Y; Evgenov Oleg V; Kuklin Vladimir N; Virag Laszlo; Pacher Pal; Southan Garry J; Salzman Andrew L; Szabo Csaba; Bjertnaes Lars J
Aerosolized linear polyethylenimine-nitric oxide/nucleophile adduct attenuates endotoxin-induced lung injury in sheep.
American journal of respiratory and critical care medicine 2002;166(11):1436-42.
2002: Pacher Pál; Cziráki Attila; Mabley Jon G; Liaudet Lucas; Papp Lajos; Szabó Csaba
Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents.
Biochemical pharmacology 2002;64(12):1785-91.
2002: Szabó Csaba; Zanchi Anne; Komjáti Katalin; Pacher Pál; Krolewski Andrzej S; Quist William C; LoGerfo Frank W; Horton Edward S; Veves Aristidis
Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity.
Circulation 2002;106(21):2680-6.
2002: Mabley Jon G; Liaudet Lucas; Pacher Pál; Southan Garry J; Groves John T; Salzman Andrew L; Szabó Csaba
Part II: beneficial effects of the peroxynitrite decomposition catalyst FP15 in murine models of arthritis and colitis.
Molecular medicine (Cambridge, Mass.) 2002;8(10):581-90.
2002: Szabó Csaba; Mabley Jon G; Moeller Suzanne M; Shimanovich Roman; Pacher Pál; Virag László; Soriano Francisco G; Van Duzer John H; Williams William; Salzman Andrew L; Groves John T
Part I: pathogenetic role of peroxynitrite in the development of diabetes and diabetic vascular complications: studies with FP15, a novel potent peroxynitrite decomposition catalyst.
Molecular medicine (Cambridge, Mass.) 2002;8(10):571-80.
2002: Bianchi Cesario; Wakiyama Hidetaka; Faro Renato; Khan Tanveer; McCully James D; Levitsky Sidney; Szabó Csaba; Sellke Frank W
A novel peroxynitrite decomposer catalyst (FP-15) reduces myocardial infarct size in an in vivo peroxynitrite decomposer and acute ischemia-reperfusion in pigs.
The Annals of thoracic surgery 2002;74(4):1201-7.
2002: Pacher Pál; Liaudet Lucas; Mabley Jon g; Komjáti Katalin; Szabó Csaba
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure.
Journal of the American College of Cardiology 2002;40(5):1006-16.
2002: Virág László; Szabó Csaba
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors.
Pharmacological reviews 2002;54(3):375-429.
2002: Németh Zoltán H; Deitch Edwin A; Szabó Csaba; Haskó György
Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells.
The American journal of pathology 2002;161(3):987-96.
2002: Haskó György; Deitch Edwin A; Szabó Csaba; Németh Zoltán H; Vizi E Sylvester
Adenosine: a potential mediator of immunosuppression in multiple organ failure.
Current opinion in pharmacology 2002;2(4):440-4.
2002: Németh Zoltán H; Deitch Edwin A; Lu Qi; Szabó Csaba; Haskó György
NHE blockade inhibits chemokine production and NF-kappaB activation in immunostimulated endothelial cells.
American journal of physiology. Cell physiology 2002;283(2):C396-403.
2002: Zhang Xiaopeng; Chen Jun; Graham Steven H; Du Lina; Kochanek Patrick M; Draviam Romesh; Guo Fengli; Nathaniel Paula D; Szabó Csaba; Watkins Simon C; Clark Robert S B
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.
Journal of neurochemistry 2002;82(1):181-91.
2002: Németh Zoltán H; Deitch Edwin A; Szabó Csaba; Mabley Jon G; Pacher Pál; Fekete Zoltán; Hauser Carl J; Haskó György
Na+/H+ exchanger blockade inhibits enterocyte inflammatory response and protects against colitis.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(1):G122-32.
2002: Virág László; Szabó Eva; Bakondi Edina; Bai Péter; Gergely Pál; Hunyadi János; Szabó Csaba
Nitric oxide-peroxynitrite-poly(ADP-ribose) polymerase pathway in the skin.
Experimental dermatology 2002;11(3):189-202.
2002: Mabley J G; Haskó G; Liaudet L; Soriano F; Southan G J; Salzman A L; Szabó C
NFkappaB1 (p50)-deficient mice are not susceptible to multiple low-dose streptozotocin-induced diabetes.
The Journal of endocrinology 2002;173(3):457-64.
2002: Pacher Pal; Mabley Jon G; Soriano Francisco G; Liaudet Lucas; Szabó Csaba
Activation of poly(ADP-ribose) polymerase contributes to the endothelial dysfunction associated with hypertension and aging.
International journal of molecular medicine 2002;9(6):659-64.
2002: Haskó György; Mabley Jon G; Németh Zoltán H; Pacher Pál; Deitch Edwin A; Szabó Csaba
Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.
Molecular medicine (Cambridge, Mass.) 2002;8(5):283-9.
2002: Szabó Csaba
Does the activation of poly (ADP-ribose) synthetase mediate tissue injury in the sepsis induced by cecal ligation and puncture? Shock 16:137-142, 2001.
Shock (Augusta, Ga.) 2002;17(5):439-40; author reply 440.
2002: Jagtap Prakash; Soriano Francisco Garcia; Virág László; Liaudet Lucas; Mabley Jon; Szabó Eva; Haskó György; Marton Anita; Lorigados Clara Batista; Gallyas Ferenc; Sümegi Balázs; Hoyt Dale G; Baloglu Erkan; VanDuzer John; Salzman Andrew L; Southan Garry J; Szabó Csaba
Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents.
Critical care medicine 2002;30(5):1071-82.
2002: Goldfarb Roy D; Marton Anita; Szabó Eva; Virág László; Salzman Andrew L; Glock Dana; Akhter Imran; McCarthy Robert; Parrillo Joseph E; Szabó Csaba
Protective effect of a novel, potent inhibitor of poly(adenosine 5'-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis.
Critical care medicine 2002;30(5):974-80.
2002: Soriano Francisco Garcia; Liaudet Lucas; Szabó Eva; Virág László; Mabley Jon G; Pacher Pál; Szabó Csaba
Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice.
Shock (Augusta, Ga.) 2002;17(4):286-92.
2002: Liaudet Lucas; Mabley Jon G; Pacher Pál; Virág László; Soriano Francisco G; Marton Anita; Haskó György; Deitch Edwin A; Szabó Csaba
Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury.
Annals of surgery 2002;235(4):568-78.
2002: Haskó György; Deitch Edwin A; Németh Zoltán H; Kuhel David G; Szabó Csaba
Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages.
The Journal of pharmacology and experimental therapeutics 2002;301(1):103-10.
2002: Pacher Pál; Mabley Jon G; Soriano Francisco G; Liaudet Lucas; Komjáti Katalin; Szabó Csaba
Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation.
British journal of pharmacology 2002;135(6):1347-50.
2002: Mabley J G; Pacher P; Southan G J; Salzman A L; Szabó C
Nicotine reduces the incidence of type I diabetes in mice.
The Journal of pharmacology and experimental therapeutics 2002;300(3):876-81.
2002: Pacher P; Liaudet L; Bai P; Virag L; Mabley J G; Haskó G; Szabó C
Activation of poly(ADP-ribose) polymerase contributes to development of doxorubicin-induced heart failure.
The Journal of pharmacology and experimental therapeutics 2002;300(3):862-7.
2002: Németh Zoltán H; Deitch Edwin A; Szabó Csaba; Fekete Zoltán; Hauser Carl J; Haskó György
Lithium induces NF-kappa B activation and interleukin-8 production in human intestinal epithelial cells.
The Journal of biological chemistry 2002;277(10):7713-9.
2002: Faro Renato; Toyoda Yoshiya; McCully James D; Jagtap Prakash; Szabo Eva; Virag Laszlo; Bianchi Cesario; Levitsky Sidney; Szabo Csaba; Sellke Frank W
Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor.
The Annals of thoracic surgery 2002;73(2):575-81.
2002: Liaudet Lucas; Pacher Pál; Mabley Jon G; Virág László; Soriano Francisco G; Haskó György; Szabó Csaba
Activation of poly(ADP-Ribose) polymerase-1 is a central mechanism of lipopolysaccharide-induced acute lung inflammation.
American journal of respiratory and critical care medicine 2002;165(3):372-7.
2002: Pacher Pal; Liaudet Lucas; Soriano Francisco Garcia; Mabley Jon G; Szabó Eva; Szabó Csaba
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes.
Diabetes 2002;51(2):514-21.
2002: Szabó Gábor; Bährle Susanne; Stumpf Nicole; Sonnenberg Karin; Szabó E Eva; Pacher Pál; Csont Tamás; Schulz Richard; Dengler Thomas J; Liaudet Lucas; Jagtap Prakash G; Southan Garry J; Vahl Christian F; Hagl Siegfried; Szabó Csaba
Poly(ADP-Ribose) polymerase inhibition reduces reperfusion injury after heart transplantation.
Circulation research 2002;90(1):100-6.
2002: Haskó György; Szabó Csaba; Németh Zoltán H; Deitch Edwin A
Dopamine suppresses IL-12 p40 production by lipopolysaccharide-stimulated macrophages via a beta-adrenoceptor-mediated mechanism.
Journal of neuroimmunology 2002;122(1-2):34-9.
2002: Bakondi Edina; Bai Péter; Szabó E Eva; Hunyadi János; Gergely Pál; Szabó Csaba; Virág László
Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(1):91-8.
2002: Liaudet Lucas; Murthy Kanneganti G K; Mabley Jon G; Pacher Pál; Soriano Francisco G; Salzman Andrew L; Szabó Csaba
Comparison of inflammation, organ damage, and oxidant stress induced by Salmonella enterica serovar Muenchen flagellin and serovar Enteritidis lipopolysaccharide.
Infection and immunity 2002;70(1):192-8.
2002: Lorch Scott; Lightfoot Richard; Ohshima Hiroshi; Virág László; Chen Qiping; Hertkorn Caryn; Weiss Marie; Souza Jose; Ischiropoulos Harry; Yermilov Vladimir; Pignatelli Brigitte; Masuda Mituharu; Szabó Csaba
Detection of peroxynitrite-induced protein and DNA modifications.
Methods in molecular biology (Clifton, N.J.) 2002;196():247-75.
2002: Ohshima Hiroshi; Virág László; Souza Jose; Yermilov Vladimir; Pignatelli Brigitte; Masuda Mitsuharu; Szabó Csaba
Detection of certain peroxynitrite-induced DNA modifications.
Methods in molecular biology (Clifton, N.J.) 2002;186():77-88.
2001: Lohinai Z; Stachlewitz R; Székely A D; Fehér E; Dézsi L; Szabó C
Evidence for the expression of cyclooxygenase-2 enzyme in periodontitis.
Life sciences 2001;70(3):279-90.
2001: Bai P; Bakondi E; Szabó E; Gergely P; Szabó C; Virág L
Partial protection by poly(ADP-ribose) polymerase inhibitors from nitroxyl-induced cytotoxity in thymocytes.
Free radical biology & medicine 2001;31(12):1616-23.
2001: Lakey J R; Suarez-Pinzon W L; Strynadka K; Korbutt G S; Rajotte R V; Mabley J G; Szabó C; Rabinovitch A
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells.
Laboratory investigation; a journal of technical methods and pathology 2001;81(12):1683-92.
2001: Soejima K; Schmalstieg F C; Traber L D; Szabo C; Salzman A; Traber D L
Role of nitric oxide in myocardial dysfunction after combined burn and smoke inhalation injury.
Burns : journal of the International Society for Burn Injuries 2001;27(8):809-15.
2001: Marton A; Pacher P; Murthy K G; Németh Z H; Haskó G; Szabó C
Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro.
International journal of molecular medicine 2001;8(6):617-21.
2001: Mabley J G; Jagtap P; Perretti M; Getting S J; Salzman A L; Virág L; Szabó E; Soriano F G; Liaudet L; Abdelkarim G E; Haskó G; Marton A; Southan G J; Szabó C
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50(11):561-9.
2001: Liaudet L; Mabley J G; Soriano F G; Pacher P; Marton A; Haskó G; Szabó C
Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture.
American journal of respiratory and critical care medicine 2001;164(7):1213-20.
2001: Soriano F G; Pacher P; Mabley J; Liaudet L; Szabó C
Rapid reversal of the diabetic endothelial dysfunction by pharmacological inhibition of poly(ADP-ribose) polymerase.
Circulation research 2001;89(8):684-91.
2001: Scott G S; Kean R B; Southan G J; Szabó C; Hooper D C
Effect of mercaptoethylguanidine scavengers of peroxynitrite on the development of experimental allergic encephalomyelitis in PLSJL mice.
Neuroscience letters 2001;311(2):125-8.
2001: Haskó G; Szabó C; Németh Z H; Deitch E A
Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression.
Immunology 2001;103(4):473-8.
2001: Soriano F G; Virág L; Szabó C
Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation.
Journal of molecular medicine (Berlin, Germany) 2001;79(8):437-48.
2001: Ploner F; Radermacher P; Theisen M; Tugtekin I F; Matejovic M; Stehr A; Szabó C; Southan G J; Georgieff M; Bruckner U B; Träger K
Effects of combined selective iNOS inhibition and peroxynitrite blockade during endotoxemia in pigs.
Shock (Augusta, Ga.) 2001;16(2):130-6.
2001: Liaudet L; Szabó E; Timashpolsky L; Virág L; Cziráki A; Szabó C
Suppression of poly (ADP-ribose) polymerase activation by 3-aminobenzamide in a rat model of myocardial infarction: long-term morphological and functional consequences.
British journal of pharmacology 2001;133(8):1424-30.
2001: Mabley J G; Suarez-Pinzon W L; Haskó G; Salzman A L; Rabinovitch A; Kun E; Szabó C
Inhibition of poly (ADP-ribose) synthetase by gene disruption or inhibition with 5-iodo-6-amino-1,2-benzopyrone protects mice from multiple-low-dose-streptozotocin-induced diabetes.
British journal of pharmacology 2001;133(6):909-19.
2001: Szabó E; Virág L; Bakondi E; Gyüre L; Haskó G; Bai P; Hunyadi J; Gergely P; Szabó C
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity.
The Journal of investigative dermatology 2001;117(1):74-80.
2001: Scott G S; Hake P; Kean R B; Virág L; Szabó C; Hooper D C
Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis.
Journal of neuroimmunology 2001;117(1-2):78-86.
2001: Liaudet L; Yang Z; Al-Affar E B; Szabó C
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
Molecular medicine (Cambridge, Mass.) 2001;7(6):406-17.
2001: Suarez-Pinzon W L; Mabley J G; Strynadka K; Power R F; Szabó C; Rabinovitch A
An inhibitor of inducible nitric oxide synthase and scavenger of peroxynitrite prevents diabetes development in NOD mice.
Journal of autoimmunity 2001;16(4):449-55.
2001: Németh Z H; Mabley J G; Deitch E A; Szabó C; Haskó G
Inhibition of the Na(+)/H(+) antiporter suppresses IL-12 p40 production by mouse macrophages.
Biochimica et biophysica acta 2001;1539(3):233-42.
2001: Wang M X; Murrell D F; Szabo C; Warren R F; Sarris M; Murrell G A
Nitric oxide in skeletal muscle: inhibition of nitric oxide synthase inhibits walking speed in rats.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2001;5(3):219-32.
2001: Garcia Soriano F; Liaudet L; Marton A; Haskó G; Batista Lorigados C; Deitch E A; Szabó C
Inosine improves gut permeability and vascular reactivity in endotoxic shock.
Critical care medicine 2001;29(4):703-8.
2001: Andreassen O A; Dedeoglu A; Friedlich A; Ferrante K L; Hughes D; Szabo C; Beal M F
Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice.
Experimental neurology 2001;168(2):419-24.
2001: Soejima K; Traber L D; Schmalstieg F C; Hawkins H; Jodoin J M; Szabo C; Szabo E; Virag L; Salzman A; Traber D L;
Role of nitric oxide in vascular permeability after combined burns and smoke inhalation injury.
American journal of respiratory and critical care medicine 2001;163(3 Pt 1):745-52.
2001: Abdelkarim G E; Gertz K; Harms C; Katchanov J; Dirnagl U; Szabó C; Endres M
Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke.
International journal of molecular medicine 2001;7(3):255-60.
2001: Zsengellér Z K; Ross G F; Trapnell B C; Szabó C; Whitsett J A
Adenovirus infection increases iNOS and peroxynitrite production in the lung.
American journal of physiology. Lung cellular and molecular physiology 2001;280(3):L503-11.
2001: Lohinai Z; Stachlewitz R; Virág L; Székely A D; Haskó G; Szabó C
Evidence for reactive nitrogen species formation in the gingivomucosal tissue.
Journal of dental research 2001;80(2):470-5.
2001: Yang Z; Szabó C
Production of interleukin-12 is under the control of endogenous interleukin-10 in myocardial ischemia-reperfusion.
Shock (Augusta, Ga.) 2001;15(1):77-9.
2001: Virág L; Szabó C
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(1):99-107.
2001: Eaves-Pyles T; Murthy K; Liaudet L; Virág L; Ross G; Soriano F G; Szabó C; Salzman A L
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunction.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(2):1248-60.
2001: Garcia Soriano F; Virág L; Jagtap P; Szabó E; Mabley J G; Liaudet L; Marton A; Hoyt D G; Murthy K G; Salzman A L; Southan G J; Szabó C
Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation.
Nature medicine 2001;7(1):108-13.
2000: Bernstein T; Szabó C; Salzman A L
Maturation-dependent sequential expression of interferon regulatory factor-1 and inducible nitric oxide synthase in cultured human enterocytes.
Shock (Augusta, Ga.) 2000;14(5):514-21.
2000: Virág L; Szabó C
BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death.
Free radical biology & medicine 2000;29(8):704-13.
2000: Haskó G; Kuhel D G; Chen J F; Schwarzschild M A; Deitch E A; Mabley J G; Marton A; Szabó C
Adenosine inhibits IL-12 and TNF-[alpha] production via adenosine A2a receptor-dependent and independent mechanisms.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2065-74.
2000: Liaudet L; Soriano F G; Szabó E; Virág L; Mabley J G; Salzman A L; Szabo C
Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):10203-8.
2000: Haskó G; Kuhel D G; Marton A; Nemeth Z H; Deitch E A; Szabó C
Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma.
Shock (Augusta, Ga.) 2000;14(2):144-9.
2000: Liaudet L; Szabó A; Soriano F G; Zingarelli B; Szabó C; Salzman A L
Poly (ADP-ribose) synthetase mediates intestinal mucosal barrier dysfunction after mesenteric ischemia.
Shock (Augusta, Ga.) 2000;14(2):134-41.
2000: Salzman A L; Linn S C; Szabo C
Progesterone inhibits inducible nitric oxide synthase mRNA expression in human intestinal epithelial cells.
International journal of molecular medicine 2000;6(2):209-16.
2000: Bank N; Kiroycheva M; Singhal P C; Anthony G M; Southan G J; Szabo C
Inhibition of nitric oxide synthase ameliorates cellular injury in sickle cell mouse kidneys.
Kidney international 2000;58(1):82-9.
2000: Szabó C
Antiperoxynitrite strategies for the experimental therapy of shock.
Critical care medicine 2000;28(6):2156-7.
2000: Vincent J L; Zhang H; Szabo C; Preiser J C
Effects of nitric oxide in septic shock.
American journal of respiratory and critical care medicine 2000;161(6):1781-5.
2000: Lorch S A; Foust R; Gow A; Arkovitz M; Salzman A L; Szabo C; Vayert B; Geffard M; Ischiropoulos H
Immunohistochemical localization of protein 3-nitrotyrosine and S-nitrosocysteine in a murine model of inhaled nitric oxide therapy.
Pediatric research 2000;47(6):798-805.
2000: Kiroycheva M; Ahmed F; Anthony G M; Szabo C; Southan G J; Bank N
Mitogen-activated protein kinase phosphorylation in kidneys of beta(s) sickle cell mice.
Journal of the American Society of Nephrology : JASN 2000;11(6):1026-32.
2000: Liaudet L; Soriano F G; Szabó C
Biology of nitric oxide signaling.
Critical care medicine 2000;28(4 Suppl):N37-52.
2000: Yang Z; Zingarelli B; Szabó C
Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury.
Circulation 2000;101(9):1019-26.
2000: Haskó G; Kuhel D G; Salzman A L; Szabó C
ATP suppression of interleukin-12 and tumour necrosis factor-alpha release from macrophages.
British journal of pharmacology 2000;129(5):909-14.
2000: Zingarelli B; Scott G S; Hake P; Salzman A L; Szabo C
Effects of nicaraven on nitric oxide-related pathways and in shock and inflammation.
Shock (Augusta, Ga.) 2000;13(2):126-34.
2000: Yang Z; Zingarelli B; Szabó C
Effect of genetic disruption of poly (ADP-ribose) synthetase on delayed production of inflammatory mediators and delayed necrosis during myocardial ischemia-reperfusion injury.
Shock (Augusta, Ga.) 2000;13(1):60-6.
2000: Parikh A A; Moon M R; Pritts T A; Fischer J E; Szabó C; Hasselgren P O; Salzman A L
IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling.
Shock (Augusta, Ga.) 2000;13(1):8-13.
2000: Haskó G; Kuhel D G; Németh Z H; Mabley J G; Stachlewitz R F; Virág L; Lohinai Z; Southan G J; Salzman A L; Szabó C
Inosine inhibits inflammatory cytokine production by a posttranscriptional mechanism and protects against endotoxin-induced shock.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):1013-9.
2000: Wilmott R W; Kitzmiller J A; Szabó C; Southan G J; Salzman A L
Mercaptoethylguanidine inhibits the inflammatory response in a murine model of chronic infection with Pseudomonas aeruginosa.
The Journal of pharmacology and experimental therapeutics 2000;292(1):88-95.
2000: Whalen M J; Clark R S; Dixon C E; Robichaud P; Marion D W; Vagni V; Graham S; Virag L; Hasko G; Stachlewitz R; Szabo C; Kochanek P M
Traumatic brain injury in mice deficient in poly-ADP(ribose) polymerase: a preliminary report.
Acta neurochirurgica. Supplement 2000;76():61-4.
2000: Soejima K; McGuire R; Snyder N; Uchida T; Szabó C; Salzman A; Traber L D; Traber D L
The effect of inducible nitric oxide synthase (iNOS) inhibition on smoke inhalation injury in sheep.
Shock (Augusta, Ga.) 2000;13(4):261-6.
1999: Virág L; Scott G S; Antal-Szalmás P; O'Connor M; Ohshima H; Szabó C
Requirement of intracellular calcium mobilization for peroxynitrite-induced poly(ADP-ribose) synthetase activation and cytotoxicity.
Molecular pharmacology 1999;56(4):824-33.
1999: Kennedy M; Wilson L; Szabo C; Salzman A L
5-aminosalicylic acid inhibits iNOS transcription in human intestinal epithelial cells.
International journal of molecular medicine 1999;4(4):437-43.
1999: Zingarelli B; Haskó G; Salzman A L; Szabó C
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
Critical care medicine 1999;27(9):1701-7.
1999: Whalen M J; Clark R S; Dixon C E; Robichaud P; Marion D W; Vagni V; Graham S H; Virag L; Hasko G; Stachlewitz R; Szabo C; Kochanek P M
Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(8):835-42.
1999: Zingarelli B; Szabó C; Salzman A L
Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase.
Gut 1999;45(2):199-209.
1999: Szabó C; Billiar T R
Novel roles of nitric oxide in hemorrhagic shock.
Shock (Augusta, Ga.) 1999;12(1):1-9.
1999: Haskó G; Szabó C
IL-12 as a therapeutic target for pharmacological modulation in immune-mediated and inflammatory diseases: regulation of T helper 1/T helper 2 responses.
British journal of pharmacology 1999;127(6):1295-304.
1999: Szabó A; Hake P; Salzman A L; Szabó C
Beneficial effects of mercaptoethylguanidine, an inhibitor of the inducible isoform of nitric oxide synthase and a scavenger of peroxynitrite, in a porcine model of delayed hemorrhagic shock.
Critical care medicine 1999;27(7):1343-50.
1999: Wilson L; Szabó C; Salzman A L
Protein kinase C-dependent activation of NF-kappaB in enterocytes is independent of IkappaB degradation.
Gastroenterology 1999;117(1):106-14.
1999: Benyó Z; Szabó C; Kovách A G; Sándor P
Prevention of the hemorrhagic hypotension-induced hepatic arterial vasoconstriction by L-arginine and naloxone.
Shock (Augusta, Ga.) 1999;11(5):342-6.
1999: Whiteman M; Szabó C; Halliwell B
Modulation of peroxynitrite- and hypochlorous acid-induced inactivation of alpha1-antiproteinase by mercaptoethylguanidine.
British journal of pharmacology 1999;126(7):1646-52.
1999: Preiser J C; Szabó C
Inhaled nitric oxide in ARDS: is the question closed?
Critical care medicine 1999;27(4):846-7.
1999: Szabó C
Simultaneous targeting or multiple pathways of shock: how promising, how novel?
Shock (Augusta, Ga.) 1999;11(4):296-7.
1999: Moon M R; Parikh A A; Pritts T A; Fischer J E; Cottongim S; Szabo C; Salzman A L; Hasselgren P O
Complement component C3 production in IL-1beta-stimulated human intestinal epithelial cells is blocked by NF-kappaB inhibitors and by transfection with ser 32/36 mutant IkappaBalpha.
The Journal of surgical research 1999;82(1):48-55.
1999: Virág L; Szabó C
Inhibition of poly(ADP-ribose) synthetase (PARS) and protection against peroxynitrite-induced cytotoxicity by zinc chelation.
British journal of pharmacology 1999;126(3):769-77.
1999: Ajuebor M N; Das A M; Virág L; Szabó C; Perretti M
Regulation of macrophage inflammatory protein-1 alpha expression and function by endogenous interleukin-10 in a model of acute inflammation.
Biochemical and biophysical research communications 1999;255(2):279-82.
1999: Ajuebor M N; Das A M; Virág L; Flower R J; Szabó C; Perretti M
Role of resident peritoneal macrophages and mast cells in chemokine production and neutrophil migration in acute inflammation: evidence for an inhibitory loop involving endogenous IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1685-91.
1999: Zingarelli B; Szabó C; Salzman A L
Blockade of Poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis.
Gastroenterology 1999;116(2):335-45.
1999: Eaves-Pyles T; Szabó C; Salzman A L
Bacterial invasion is not required for activation of NF-kappaB in enterocytes.
Infection and immunity 1999;67(2):800-4.
1999: Grupp I L; Jackson T M; Hake P; Grupp G; Szabó C
Protection against hypoxia-reoxygenation in the absence of poly (ADP-ribose) synthetase in isolated working hearts.
Journal of molecular and cellular cardiology 1999;31(1):297-303.
1999: Scott G S; Jakeman L B; Stokes B T; Szabó C
Peroxynitrite production and activation of poly (adenosine diphosphate-ribose) synthetase in spinal cord injury.
Annals of neurology 1999;45(1):120-4.
1999: Salzman A L; Preiser J C; Setchell K D; Szabo C
Isoflavone-mediated inhibition of tyrosine kinase: a novel antiinflammatory approach.
Journal of medicinal food 1999;2(3-4):179-81.
1998: Ajuebor M N; Virág L; Flower R J; Perretti M; Szabó C
Role of inducible nitric oxide synthase in the regulation of neutrophil migration in zymosan-induced inflammation.
Immunology 1998;95(4):625-30.
1998: Virág L; Marmer D J; Szabó C
Crucial role of apopain in the peroxynitrite-induced apoptotic DNA fragmentation.
Free radical biology & medicine 1998;25(9):1075-82.
1998: Zingarelli B; Cuzzocrea S; Szabó C; Salzman A L
Mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, reduces trinitrobenzene sulfonic acid-induced colonic damage in rats.
The Journal of pharmacology and experimental therapeutics 1998;287(3):1048-55.
1998: Haskó G; Shanley T P; Egnaczyk G; Németh Z H; Salzman A L; Vizi E S; Szabó C
Exogenous and endogenous catecholamines inhibit the production of macrophage inflammatory protein (MIP) 1 alpha via a beta adrenoceptor mediated mechanism.
British journal of pharmacology 1998;125(6):1297-303.
1998: Southan G J; Salzman A L; Szabó C
Hydroxyguanidines inhibit peroxynitrite-induced oxidation.
Free radical biology & medicine 1998;25(8):914-25.
1998: Szabó A; Hake P; Salzman A L; Szabó C
3-Aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, improves hemodynamics and prolongs survival in a porcine model of hemorrhagic shock.
Shock (Augusta, Ga.) 1998;10(5):347-53.
1998: Haskó G; Szabó C
Regulation of cytokine and chemokine production by transmitters and co-transmitters of the autonomic nervous system.
Biochemical pharmacology 1998;56(9):1079-87.
1998: Haskó G; Németh Z H; Vizi E S; Salzman A L; Szabó C
An agonist of adenosine A3 receptors decreases interleukin-12 and interferon-gamma production and prevents lethality in endotoxemic mice.
European journal of pharmacology 1998;358(3):261-8.
1998: Virág L; Salzman A L; Szabó C
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3753-9.
1998: Szabó C; Scott G S; Virág L; Egnaczyk G; Salzman A L; Shanley T P; Haskó G
Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists.
British journal of pharmacology 1998;125(2):379-87.
1998: Benyó Z; Szabó C; Csáki C; Wahl M; Kovách A G; Sándor P
Effect of L-arginine on adrenal and renal blood flows during hemorrhage in cats.
Kidney international. Supplement 1998;67():S221-3.
1998: Brahn E; Banquerigo M L; Firestein G S; Boyle D L; Salzman A L; Szabó C
Collagen induced arthritis: reversal by mercaptoethylguanidine, a novel antiinflammatory agent with a combined mechanism of action.
The Journal of rheumatology 1998;25(9):1785-93.
1998: Panas D; Khadour F H; Szabó C; Schulz R
Proinflammatory cytokines depress cardiac efficiency by a nitric oxide-dependent mechanism.
The American journal of physiology 1998;275(3 Pt 2):H1016-23.
1998: Haskó G; Szabó C; Németh Z H; Salzman A L; Vizi E S
Stimulation of beta-adrenoceptors inhibits endotoxin-induced IL-12 production in normal and IL-10 deficient mice.
Journal of neuroimmunology 1998;88(1-2):57-61.
1998: Virág L; Scott G S; Cuzzocrea S; Marmer D; Salzman A L; Szabó C
Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation.
Immunology 1998;94(3):345-55.
1998: Haskó G; Szabó C; Németh Z H; Lendvai B; Vizi E S
Modulation by dantrolene of endotoxin-induced interleukin-10, tumour necrosis factor-alpha and nitric oxide production in vivo and in vitro.
British journal of pharmacology 1998;124(6):1099-106.
1998: Szabó C; Dawson V L
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia-reperfusion.
Trends in pharmacological sciences 1998;19(7):287-98.
1998: Zingarelli B; Salzman A L; Szabó C
Genetic disruption of poly (ADP-ribose) synthetase inhibits the expression of P-selectin and intercellular adhesion molecule-1 in myocardial ischemia/reperfusion injury.
Circulation research 1998;83(1):85-94.
1998: Virág L; Haskó G; Salzman A L; Szabó C
NADPH diaphorase histochemistry detects inducible nitric oxide synthetase activity in the thymus of naive and staphylococcal enterotoxin B-stimulated mice.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1998;46(7):787-91.
1998: Endres M; Scott G S; Salzman A L; Kun E; Moskowitz M A; Szabó C
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development.
European journal of pharmacology 1998;351(3):377-82.
1998: Szabó C
Role of nitric oxide in endotoxic shock. An overview of recent advances.
Annals of the New York Academy of Sciences 1998;851():422-5.
1998: Szabó C
Regulation of the expression of the inducible isoform of nitric oxide synthase by glucocorticoids.
Annals of the New York Academy of Sciences 1998;851():336-41.
1998: Németh Z H; Haskó G; Szabó C; Salzman A L; Vizi E S
Calcium channel blockers and dantrolene differentially regulate the production of interleukin-12 and interferon-gamma in endotoxemic mice.
Brain research bulletin 1998;46(3):257-61.
1998: Gilad E; Wong H R; Zingarelli B; Virág L; O'Connor M; Salzman A L; Szabó C
Melatonin inhibits expression of the inducible isoform of nitric oxide synthase in murine macrophages: role of inhibition of NFkappaB activation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(9):685-93.
1998: Zingarelli B; Virág L; Szabó A; Cuzzocrea S; Salzman A L; Szabó C
Oxidation, tyrosine nitration and cytostasis induction in the absence of inducible nitric oxide synthase.
International journal of molecular medicine 1998;1(5):787-95.
1998: Szabó C
Role of poly(ADP-ribose)synthetase in inflammation.
European journal of pharmacology 1998;350(1):1-19.
1998: Endres M; Scott G; Namura S; Salzman A L; Huang P L; Moskowitz M A; Szabó C
Role of peroxynitrite and neuronal nitric oxide synthase in the activation of poly(ADP-ribose) synthetase in a murine model of cerebral ischemia-reperfusion.
Neuroscience letters 1998;248(1):41-4.
1998: Szabó C
Potential role of the peroxynitrate-poly(ADP-ribose) synthetase pathway in a rat model of severe hemorrhagic shock.
Shock (Augusta, Ga.) 1998;9(5):341-4.
1998: Haskó G; Virág L; Egnaczyk G; Salzman A L; Szabó C
The crucial role of IL-10 in the suppression of the immunological response in mice exposed to staphylococcal enterotoxin B.
European journal of immunology 1998;28(4):1417-25.
1998: Szabó C; Virág L; Cuzzocrea S; Scott G S; Hake P; O'Connor M P; Zingarelli B; Salzman A; Kun E
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3867-72.
1998: Kennedy M; Denenberg A G; Szabó C; Salzman A L
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells.
Gastroenterology 1998;114(3):510-8.
1998: Haskó G; Szabó C; Németh Z H; Salzman A L; Vizi E S
Suppression of IL-12 production by phosphodiesterase inhibition in murine endotoxemia is IL-10 independent.
European journal of immunology 1998;28(2):468-72.
1998: Cuzzocrea S; Zingarelli B; O'Connor M; Salzman A L; Szabó C
Effect of L-buthionine-(S,R)-sulphoximine, an inhibitor of gamma-glutamylcysteine synthetase on peroxynitrite- and endotoxic shock-induced vascular failure.
British journal of pharmacology 1998;123(3):525-37.
1998: Lohinai Z; Benedek P; Fehér E; Györfi A; Rosivall L; Fazekas A; Salzman A L; Szabó C
Protective effects of mercaptoethylguanidine, a selective inhibitor of inducible nitric oxide synthase, in ligature-induced periodontitis in the rat.
British journal of pharmacology 1998;123(3):353-60.
1998: Cuzzocrea S; Zingarelli B; Hake P; Salzman A L; Szabó C
Antiinflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation.
Free radical biology & medicine 1998;24(3):450-9.
1998: Cuzzocrea S; Zingarelli B; Gilad E; Hake P; Salzman A L; Szabó C
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation.
European journal of pharmacology 1998;342(1):67-76.
1998: Salzman A L; Eaves-Pyles T; Linn S C; Denenberg A G; Szabó C
Bacterial induction of inducible nitric oxide synthase in cultured human intestinal epithelial cells.
Gastroenterology 1998;114(1):93-102.
1998: Szabó A; Salzman A L; Szabó C
Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock.
Life sciences 1998;63(23):2133-9.
1998: Haskó G; Németh Z H; Szabó C; Zsilla G; Salzman A L; Vizi E S
Isoproterenol inhibits Il-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages.
Brain research bulletin 1998;45(2):183-7.
1997: O'Connor M; Salzman A L; Szabó C
Role of peroxynitrite in the protein oxidation and apoptotic DNA fragmentation in vascular smooth muscle cells stimulated with bacterial lipopolysaccharide and interferon-gamma.
Shock (Augusta, Ga.) 1997;8(6):439-43.
1997: Moon R; Parikh A A; Szabo C; Fischer J E; Salzman A L; Hasselgren P O
Complement C3 production in human intestinal epithelial cells is regulated by interleukin 1beta and tumor necrosis factor alpha.
Archives of surgery (Chicago, Ill. : 1960) 1997;132(12):1289-93.
1997: Brilli R J; Krafte-Jacobs B; Smith D J; Roselle D; Passerini D; Vromen A; Moore L; Szabó C; Salzman A L
Intratracheal instillation of a novel NO/nucleophile adduct selectively reduces pulmonary hypertension.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(6):1968-75.
1997: Németh Z H; Szabó C; Haskó G; Salzman A L; Vizi E S
Effect of the phosphodiesterase III inhibitor amrinone on cytokine and nitric oxide production in immunostimulated J774.1 macrophages.
European journal of pharmacology 1997;339(2-3):215-21.
1997: Zingarelli B; Cuzzocrea S; Zsengellér Z; Salzman A L; Szabó C
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.
Cardiovascular research 1997;36(2):205-15.
1997: Cuzzocrea S; Tailor A; Zingarelli B; Salzman A L; Flower R J; Szabó C; Perretti M
Lipocortin 1 protects against splanchnic artery occlusion and reperfusion injury by affecting neutrophil migration.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(10):5089-97.
1997: Szabó C; Ohshima H
DNA damage induced by peroxynitrite: subsequent biological effects.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(5):373-85.
1997: Zingarelli B; Ischiropoulos H; Salzman A L; Szabó C
Amelioration by mercaptoethylguanidine of the vascular and energetic failure in haemorrhagic shock in the anesthetised rat.
European journal of pharmacology 1997;338(1):55-65.
1997: Cuzzocrea S; Zingarelli B; O'Connor M; Salzman A L; Caputi A P; Szabó C
Role of peroxynitrite and activation of poly (ADP-ribose) synthase in the vascular failure induced by zymosan-activated plasma.
British journal of pharmacology 1997;122(3):493-503.
1997: Parikh A A; Salzman A L; Fischer J E; Szabó C; Hasselgren P O
Interleukin-1 beta and interferon-gamma regulate interleukin-6 production in cultured human intestinal epithelial cells.
Shock (Augusta, Ga.) 1997;8(4):249-55.
1997: Szabó C; Lim L H; Cuzzocrea S; Getting S J; Zingarelli B; Flower R J; Salzman A L; Perretti M
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects.
The Journal of experimental medicine 1997;186(7):1041-9.
1997: Gardner P R; Costantino G; Szabó C; Salzman A L
Nitric oxide sensitivity of the aconitases.
The Journal of biological chemistry 1997;272(40):25071-6.
1997: Cuzzocrea S; Zingarelli B; Gilad E; Hake P; Salzman A L; Szabó C
Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity.
Journal of pineal research 1997;23(2):106-16.
1997: Gilad E; Zingarelli B; Salzman A L; Szabó C
Protection by inhibition of poly (ADP-ribose) synthetase against oxidant injury in cardiac myoblasts In vitro.
Journal of molecular and cellular cardiology 1997;29(9):2585-97.
1997: Krafte-Jacobs B; Brilli R; Szabó C; Denenberg A; Moore L; Salzman A L
Circulating methemoglobin and nitrite/nitrate concentrations as indicators of nitric oxide overproduction in critically ill children with septic shock.
Critical care medicine 1997;25(9):1588-93.
1997: Szabó C
Role of poly(ADP-ribose) synthetase activation in the suppression of cellular energetics in response to nitric oxide and peroxynitrite.
Biochemical Society transactions 1997;25(3):919-24.
1997: Southan G J; Gauld D; Lubeskie A; Zingarelli B; Cuzzocrea S; Salzman A L; Szabó C; Wolff D J
Inhibition of nitric oxide synthase with pyrazole-1-carboxamidine and related compounds.
Biochemical pharmacology 1997;54(3):409-17.
1997: Szabó C
Nitric oxide, perioxynitrite and poly(ADP-ribose) synthetase in anaphylactic shock.
Shock (Augusta, Ga.) 1997;8(2):153-4.
1997: Szabó C; Cuzzocrea S; Zingarelli B; O'Connor M; Salzman A L
Endothelial dysfunction in a rat model of endotoxic shock. Importance of the activation of poly (ADP-ribose) synthetase by peroxynitrite.
The Journal of clinical investigation 1997;100(3):723-35.
1997: Invernizzi P; Salzman A L; Szabó C; Ueta I; O'Connor M; Setchell K D
Ursodeoxycholate inhibits induction of NOS in human intestinal epithelial cells and in vivo.
The American journal of physiology 1997;273(1 Pt 1):G131-8.
1997: Cuzzocrea S; Zingarelli B; Costantino G; Szabó A; Salzman A L; Caputi A P; Szabó C
Beneficial effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase in a rat model of splanchnic artery occlusion and reperfusion.
British journal of pharmacology 1997;121(6):1065-74.
1997: Linn S C; Morelli P J; Edry I; Cottongim S E; Szabó C; Salzman A L
Transcriptional regulation of human inducible nitric oxide synthase gene in an intestinal epithelial cell line.
The American journal of physiology 1997;272(6 Pt 1):G1499-508.
1997: Szabó C; O'Connor M; Salzman A L
Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages.
FEBS letters 1997;409(2):147-50.
1997: Németh Z H; Haskó G; Szabó C; Vizi E S
Amrinone and theophylline differentially regulate cytokine and nitric oxide production in endotoxemic mice.
Shock (Augusta, Ga.) 1997;7(5):371-5.
1997: Arkovitz M S; Szabó C; Garcia V F; Wong H R; Wispé J R
Differential effects of hyperoxia on the inducible and constitutive isoforms of nitric oxide synthase in the lung.
Shock (Augusta, Ga.) 1997;7(5):345-50.
1997: Kilbourn R G; Traber D L; Szabó C
Nitric oxide and shock.
Disease-a-month : DM 1997;43(5):277-348.
1997: Suarez-Pinzon W L; Szabó C; Rabinovitch A
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.
Diabetes 1997;46(5):907-11.
1997: Szabó C; Haskó G; Németh Z H; Vizi E S
Calcium entry blockers increase interleukin-10 production in endotoxemia.
Shock (Augusta, Ga.) 1997;7(4):304-7.
1997: Kilbourn R G; Szabó C; Traber D L
Beneficial versus detrimental effects of nitric oxide synthase inhibitors in circulatory shock: lessons learned from experimental and clinical studies.
Shock (Augusta, Ga.) 1997;7(4):235-46.
1997: Szabó C; Ferrer-Sueta G; Zingarelli B; Southan G J; Salzman A L; Radi R
Mercaptoethylguanidine and guanidine inhibitors of nitric-oxide synthase react with peroxynitrite and protect against peroxynitrite-induced oxidative damage.
The Journal of biological chemistry 1997;272(14):9030-6.
1997: Salzman A L; Vromen A; Denenberg A; Szabó C
K(ATP)-channel inhibition improves hemodynamics and cellular energetics in hemorrhagic shock.
The American journal of physiology 1997;272(2 Pt 2):H688-94.
1997: Arkovitz M S; Garcia V F; Szabó C; McConnell K; Bove K; Wispé J R
Decreased pulmonary compliance is an early indicator of pulmonary oxygen injury.
The Journal of surgical research 1997;67(2):193-8.
1997: Sun X; Wei S; Szabo C; Dusting G J
Depression of the inotropic action of isoprenaline by nitric oxide synthase induction in rat isolated hearts.
European journal of pharmacology 1997;320(1):29-35.
1997: Szabó C; Saunders C; O'Connor M; Salzman A L
Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells.
American journal of respiratory cell and molecular biology 1997;16(2):105-9.
1997: Zingarelli B; Southan G J; Gilad E; O'Connor M; Salzman A L; Szabó C
The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity.
British journal of pharmacology 1997;120(3):357-66.
1997: Murrell G A; Szabo C; Hannafin J A; Jang D; Dolan M M; Deng X H; Murrell D F; Warren R F
Modulation of tendon healing by nitric oxide.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46(1):19-27.
1997: Zingarelli B; Day B J; Crapo J D; Salzman A L; Szabó C
The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock.
British journal of pharmacology 1997;120(2):259-67.
1997: Szabó C; Haskó G; Zingarelli B; Németh Z H; Salzman A L; Kvetan V; Pastores S M; Vizi E S
Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia.
Immunology 1997;90(1):95-100.
1997: Hrabák A; Bajor T; Southan G J; Salzman A L; Szabó C
Comparison of the inhibitory effect of isothiourea and mercapto-alkylguanidine derivatives on the alternative pathways of arginine metabolism in macrophages.
Life sciences 1997;60(26):PL395-401.
1997: Gilad E; Cuzzocrea S; Zingarelli B; Salzman A L; Szabó C
Melatonin is a scavenger of peroxynitrite.
Life sciences 1997;60(10):PL169-74.
1996: Szabó C; Wong H R; Salzman A L
Pre-exposure to heat shock inhibits peroxynitrite-induced activation of poly(ADP) ribosyltransferase and protects against peroxynitrite cytotoxicity in J774 macrophages.
European journal of pharmacology 1996;315(2):221-6.
1996: Haskó G; Szabó C; Németh Z H; Kvetan V; Pastores S M; Vizi E S
Adenosine receptor agonists differentially regulate IL-10, TNF-alpha, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(10):4634-40.
1996: Vromen A; Arkovitz M S; Zingarelli B; Salzman A L; Garcia V F; Szabó C
Low-level expression and limited role for the inducible isoform of nitric oxide synthase in the vascular hyporeactivity and mortality associated with cecal ligation and puncture in the rat.
Shock (Augusta, Ga.) 1996;6(4):248-53.
1996: Jang D; Szabo C; Murrell G A
S-substituted isothioureas are potent inhibitors of nitric oxide biosynthesis in cartilage.
European journal of pharmacology 1996;312(3):341-7.
1996: Szabo C; Kilbourn R
Nitric oxide and sepsis.
JAMA : the journal of the American Medical Association 1996;276(10):781-2.
1996: Vromen A; Szabó C; Southan G J; Salzman A L
Effects of S-isopropyl isothiourea, a potent inhibitor of nitric oxide synthase, in severe hemorrhagic shock.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(2):707-15.
1996: Arkovitz M S; Wispé J R; Garcia V F; Szabó C
Selective inhibition of the inducible isoform of nitric oxide synthase prevents pulmonary transvascular flux during acute endotoxemia.
Journal of pediatric surgery 1996;31(8):1009-15.
1996: Szabó C
The pathophysiological role of peroxynitrite in shock, inflammation, and ischemia-reperfusion injury.
Shock (Augusta, Ga.) 1996;6(2):79-88.
1996: Szabó C; Bryk R; Zingarelli B; Southan G J; Gahman T C; Bhat V; Salzman A L; Wolff D J
Pharmacological characterization of guanidinoethyldisulphide (GED), a novel inhibitor of nitric oxide synthase with selectivity towards the inducible isoform.
British journal of pharmacology 1996;118(7):1659-68.
1996: Szabó C; Salzman A L
Inhibition of terminal calcium overload protects against peroxynitrite-induced cellular injury in macrophages.
Immunology letters 1996;51(3):163-7.
1996: Szabó C
Nitric oxide, intracellular calcium overload, and cytotoxicity.
Shock (Augusta, Ga.) 1996;6(1):25-6.
1996: Wood P J; Sansom J M; Stratford I J; Adams G E; Szabo C; Thiemermann C; Vane J R
Changes in energy metabolism and X-ray sensitivity in murine tumours by the nitric oxide donor SIN-1.
The British journal of cancer. Supplement 1996;27():S177-80.
1996: Szabó C; Salzman A L
Inhibition of ATP-activated potassium channels exerts pressor effects and improves survival in a rat model of severe hemorrhagic shock.
Shock (Augusta, Ga.) 1996;5(6):391-4.
1996: Szabó C; Zingarelli B; Salzman A L
Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite.
Circulation research 1996;78(6):1051-63.
1996: Salzman A; Denenberg A G; Ueta I; O'Connor M; Linn S C; Szabó C
Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers.
The American journal of physiology 1996;270(4 Pt 1):G565-73.
1996: Zingarelli B; Salzman A L; Szabó C
Protective effects of nicotinamide against nitric oxide-mediated delayed vascular failure in endotoxic shock: potential involvement of polyADP ribosyl synthetase.
Shock (Augusta, Ga.) 1996;5(4):258-64.
1996: Haskó G; Szabó C; Merkel K; Bencsics A; Zingarelli B; Kvetan V; Vizi E S
Modulation of lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production by dopamine receptor agonists and antagonists in mice.
Immunology letters 1996;49(3):143-7.
1996: Szabó C; Zingarelli B; O'Connor M; Salzman A L
DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):1753-8.
1996: Southan G J; Zingarelli B; O'Connor M; Salzman A L; Szabó C
Spontaneous rearrangement of aminoalkylisothioureas into mercaptoalkylguanidines, a novel class of nitric oxide synthase inhibitors with selectivity towards the inducible isoform.
British journal of pharmacology 1996;117(4):619-32.
1996: Szabó C; Day B J; Salzman A L
Evaluation of the relative contribution of nitric oxide and peroxynitrite to the suppression of mitochondrial respiration in immunostimulated macrophages using a manganese mesoporphyrin superoxide dismutase mimetic and peroxynitrite scavenger.
FEBS letters 1996;381(1-2):82-6.
1996: Southan G J; Szabó C
Selective pharmacological inhibition of distinct nitric oxide synthase isoforms.
Biochemical pharmacology 1996;51(4):383-94.
1996: Murrell G A; Doland M M; Jang D; Szabo C; Warren R F; Hannafin J A
Nitric oxide: an important articular free radical.
The Journal of bone and joint surgery. American volume 1996;78(2):265-74.
1996: Zingarelli B; O'Connor M; Wong H; Salzman A L; Szabó C
Peroxynitrite-mediated DNA strand breakage activates poly-adenosine diphosphate ribosyl synthetase and causes cellular energy depletion in macrophages stimulated with bacterial lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(1):350-8.
1996: Szabó C
DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite.
Free radical biology & medicine 1996;21(6):855-69.
1996: Szabó C
Physiological and pathophysiological roles of nitric oxide in the central nervous system.
Brain research bulletin 1996;41(3):131-41.
1996: Benyó Z; Szabó C; Velkei M H; Bohus B; Wahl M; Sándor P
Intravenous beta-endorphin administration fails to alter hypothalamic blood flow in rats expressing normal or reduced nitric oxide synthase activity.
Peptides 1996;17(4):733-6.
1996: Southan G J; Salzman A L; Szabo C
Potent inhibition of the inducible isoform of nitric oxide synthase by aminoethylisoselenourea and related compounds.
Life sciences 1996;58(14):1139-48.
1995: Southan G J; Szabó C; Connor M P; Salzman A L; Thiemermann C
Amidines are potent inhibitors of nitric oxide synthases: preferential inhibition of the inducible isoform.
European journal of pharmacology 1995;291(3):311-8.
1995: Marczin N; Tekeres M; Salzman A L; Szabó C
Methylene blue infusion in septic shock.
Critical care medicine 1995;23(11):1936-8.
1995: Hattori Y; Szabó C; Gross S; Thiemermann C; Vane J R
Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthase in vitro and in vivo.
European journal of pharmacology 1995;291(2):83-90.
1995: Perretti M; Szabó C; Thiemermann C
Effect of interleukin-4 and interleukin-10 on leucocyte migration and nitric oxide production in the mouse.
British journal of pharmacology 1995;116(4):2251-7.
1995: Benyó Z; Szabó C; Stuiver B T; Bohus B; Sándor P
Hypothalamic blood flow remains unaltered following chronic nitric oxide synthase blockade in rats.
Neuroscience letters 1995;198(2):127-30.
1995: Szabó C; Salzman A L; Ischiropoulos H
Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occurs in early stages of endotoxic and hemorrhagic shock and ischemia-reperfusion injury.
FEBS letters 1995;372(2-3):229-32.
1995: Szabó C; Salzman A L
Endogenous peroxynitrite is involved in the inhibition of mitochondrial respiration in immuno-stimulated J774.2 macrophages.
Biochemical and biophysical research communications 1995;209(2):739-43.
1995: Wu C C; Chen S J; Szabó C; Thiemermann C; Vane J R
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
British journal of pharmacology 1995;114(8):1666-72.
1995: Szabó C; Salzman A L; Ischiropoulos H
Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo.
FEBS letters 1995;363(3):235-8.
1995: Szabó C
Alterations in nitric oxide production in various forms of circulatory shock.
New horizons (Baltimore, Md.) 1995;3(1):2-32.
1995: Southan G J; Szabó C; Thiemermann C
Isothioureas: potent inhibitors of nitric oxide synthases with variable isoform selectivity.
British journal of pharmacology 1995;114(2):510-6.
1995: Szabó C; Thiemermann C
Regulation of the expression of the inducible isoform of nitric oxide synthase.
Advances in pharmacology (San Diego, Calif.) 1995;34():113-53.
1994: Wood P J; Sansom J M; Butler S A; Stratford I J; Cole S M; Szabo C; Thiemermann C; Adams G E
Induction of hypoxia in experimental murine tumors by the nitric oxide synthase inhibitor, NG-nitro-L-arginine.
Cancer research 1994;54(24):6458-63.
1994: Szabó C; Southan G J; Thiemermann C
Beneficial effects and improved survival in rodent models of septic shock with S-methylisothiourea sulfate, a potent and selective inhibitor of inducible nitric oxide synthase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12472-6.
1994: Szabó C; Csáki C; Benyó Z; Marczis J; Reivich M; Kovách A G
Effect of superoxide dismutase on hemorrhagic hypotension and retransfusion-evoked middle cerebral artery endothelial dysfunction.
Circulatory shock 1994;44(3):104-10.
1994: Szabó C; Southan G J; Thiemermann C; Vane J R
The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites.
British journal of pharmacology 1994;113(3):757-66.
1994: Southan G J; Szabó C; Thiemermann C
Inhibition of the induction of nitric oxide synthase by spermine is modulated by aldehyde dehydrogenase.
Biochemical and biophysical research communications 1994;203(3):1638-44.
1994: Szabó C; Thiemermann C
Invited opinion: role of nitric oxide in hemorrhagic, traumatic, and anaphylactic shock and thermal injury.
Shock (Augusta, Ga.) 1994;2(2):145-55.
1994: Szabó C; Southan G J; Wood E; Thiemermann C; Vane J R
Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages: requirement of a serum factor.
British journal of pharmacology 1994;112(2):355-6.
1994: Wood P J; Sansom J M; Stratford I J; Adams G E; Szabo C; Thiemermann C; Vane J R
Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine.
International journal of radiation oncology, biology, physics 1994;29(3):443-7.
1994: Wu C C; Szabó C; Chen S J; Thiemermann C; Vane J R
Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin.
Biochemical and biophysical research communications 1994;201(1):436-42.
1994: Szabó C; Thiemermann C; Wu C C; Perretti M; Vane J R
Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(1):271-5.
1993: Szabó C; Wu C C; Mitchell J A; Gross S S; Thiemermann C; Vane J R
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide.
Circulation research 1993;73(6):991-9.
1993: Szabó C; Wu C C; Gross S S; Thiemermann C; Vane J R
Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo.
European journal of pharmacology 1993;250(1):157-60.
1993: Szabó C; Thiemermann C; Vane J R
Dihydropyridine antagonists and agonists of calcium channels inhibit the induction of nitric oxide synthase by endotoxin in cultured macrophages.
Biochemical and biophysical research communications 1993;196(2):825-30.
1993: Szabó C; Thiemermann C; Vane J R
Inhibition of the production of nitric oxide and vasodilator prostaglandins attenuates the cardiovascular response to bacterial endotoxin in adrenalectomized rats.
Proceedings. Biological sciences / The Royal Society 1993;253(1338):233-8.
1993: Thiemermann C; Wu C C; Szabó C; Perretti M; Vane J R
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock.
British journal of pharmacology 1993;110(1):177-82.
1993: Szabó C; Mitchell J A; Gross S S; Thiemermann C; Vane J R
Nifedipine inhibits the induction of nitric oxide synthase by bacterial lipopolysaccharide.
The Journal of pharmacology and experimental therapeutics 1993;265(2):674-80.
1993: Wood P J; Stratford I J; Adams G E; Szabo C; Thiemermann C; Vane J R
Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability.
Biochemical and biophysical research communications 1993;192(2):505-10.
1993: Szabó C; Mitchell J A; Thiemermann C; Vane J R
Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock.
British journal of pharmacology 1993;108(3):786-92.
1993: Thiemermann C; Szabó C; Mitchell J A; Vane J R
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):267-71.
1992: Szabó C; Csáki C; Benyó Z; Reivich M; Kovách A G
Role of the L-arginine-nitric oxide pathway in the changes in cerebrovascular reactivity following hemorrhagic hypotension and retransfusion.
Circulatory shock 1992;37(4):307-16.
1992: Kovách A G; Szabó C; Benyó Z; Csáki C; Greenberg J H; Reivich M
Effects of NG-nitro-L-arginine and L-arginine on regional cerebral blood flow in the cat.
The Journal of physiology 1992;449():183-96.
1992: Csáki C; Szabó C; Benyó Z; Kovách A G
Role of platelet-activating factor in the development of endothelial dysfunction in hemorrhagic hypotension and retransfusion.
Thrombosis research 1992;66(1):23-31.
1992: Szabó C; Faragó M; Horváth I; Lohinai Z; Kovách A G
Hemorrhagic hypotension impairs endothelium-dependent relaxations in the renal artery of the cat.
Circulatory shock 1992;36(3):238-41.
1992: Szabó C; Bérczi V; Schneider F; Kovách A G; Monos E
Role of endothelium in the response of the vein wall to magnesium withdrawal.
Pflügers Archiv : European journal of physiology 1992;420(2):140-5.
1992: Szabó C; Hardebo J E; Salford L G
Role of endothelium in the responses of human intracranial arteries to a slight reduction of extracellular magnesium.
Experimental physiology 1992;77(1):209-11.
1992: Szabó C; Hardebo J E
Regional differences in the contractile activity of neuropeptide Y, endothelin, oxytocin and vasopressin: comparison with non-peptidergic constrictors. An in vitro study in the basilar and mesenteric arteries of the rat.
Acta physiologica Hungarica 1992;79(3):281-93.
1992: Szabó C; Faragó M; Dóra E
Effect of small changes in extracellular magnesium concentration on the tone of feline mesenteric arteries: involvement of endothelium.
Acta physiologica Hungarica 1992;79(3):295-303.
1991: Kovách A G; Szabó C; Faragó M; Lohinai Z; Fehér E
Effect of hemorrhagic hypotension on cerebrovascular reactivity and ultrastructure in the cat.
Stroke; a journal of cerebral circulation 1991;22(12):1541-7.
1991: Benyó Z; Kiss G; Szabó C; Csáki C; Kovách A G
Importance of basal nitric oxide synthesis in regulation of myocardial blood flow.
Cardiovascular research 1991;25(8):700-3.
1991: Szabó C; Faragó M; Dóra E; Horváth I; Kovách A G
Endothelium-dependent influence of small changes in extracellular magnesium concentration on the tone of feline middle cerebral arteries.
Stroke; a journal of cerebral circulation 1991;22(6):785-9.
1991: Szabó C; Hardebo J E; Owman C
An amplifying effect of exogenous and neurally stored 5-hydroxytryptamine on the neurogenic contraction in rat tail artery.
British journal of pharmacology 1991;102(2):401-7.
1991: Faragó M; Szabó C; Dóra E; Horváth I; Kovách A G
Contractile and endothelium-dependent dilatory responses of cerebral arteries at various extracellular magnesium concentrations.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1991;11(1):161-4.
1991: Csaki C; Szabo C; Benyo Z; Reivich M; Kovach A G
Activated neutrophils inhibit cerebrovascular endothelium-dependent relaxations in vitro.
Life sciences 1991;49(15):1087-94.
1991: Faragó M; Szabó C; Horváth I; Dóra E; Kovách A G
Differential vascular actions of ethanol in feline middle cerebral and mesenteric artery.
Acta physiologica Hungarica 1991;78(2):119-25.
1991: Szabó C; Faragó M; Dóra E; Horváth I; Kovách A G
Influence of extracellular magnesium on the contractile and endothelium-dependent dilatory responses of feline mesenteric arteries.
Acta physiologica Hungarica 1991;78(1):19-26.
1990: Szabó C; Hardebo J E
Characterization of a neurogenic and a direct smooth muscle component in the contractile response to electrical field stimulation in rat tail artery.
Journal of autonomic pharmacology 1990;10(5):283-96.
1990: Szabó C; Dóra E; Faragó M; Horváth I; Kovách A G
Noradrenaline induces rhythmic contractions of feline middle cerebral artery at low extracellular magnesium concentration.
Blood vessels 1990;27(6):373-7.
1989: Kovach A G; Dora E; Farago M; Horvath I H; Szabo C
Regional differences in the regulation of contraction-relaxation machinery of vascular smooth muscle.
Advances in experimental medicine and biology 1989;248():601-9.
1989: Dora E; Feher E; Farago M; Horvath I; Szabo C
Mechanism of hemoglobin-induced spasm in the isolated middle cerebral artery of the cat.
Advances in experimental medicine and biology 1989;248():533-42.

Sign-in to see more