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John Helmann

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Bacillus subtilis

Chemicals & Drugs

Physiology

Concepts & Ideas

Molecular Sequence Data

Genes & Molecular Sequences

Devices

Oligonucleotide Array Sequence Analysis

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Co-Publications
Name
11
Gaballa, Ahmed
9
Cao, Min
7
Mascher, Thorsten
7
Lee, Jin-Won
6
Fuangthong, Mayuree
6
Wang, Tao
6
Ye, Rick
5
Moore, Charles
5
Huang, X
5
Chamberlin, Michael
4
Eiamphungporn, Warawan
4
Antelmann, Haike
4
Brennan, Richard
4
Bsat, Nada
4
Butcher, Bronwyn

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Publications

TOP 3
Gabriel Scott E; Helmann John D
Contributions of Zur-controlled ribosomal proteins to growth under zinc starvation conditions.
Luo Yun; Helmann John D
Extracytoplasmic function sigma factors with overlapping promoter specificity regulate sublancin production in Bacillus subtilis.
Hachmann Anna-Barbara; Angert Esther R; Helmann John D
Genetic analysis of factors affecting susceptibility of Bacillus subtilis to daptomycin.

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All Publications

2009: Gabriel Scott E; Helmann John D
Contributions of Zur-controlled ribosomal proteins to growth under zinc starvation conditions.
Journal of bacteriology 2009;191(19):6116-22.
2009: Luo Yun; Helmann John D
Extracytoplasmic function sigma factors with overlapping promoter specificity regulate sublancin production in Bacillus subtilis.
Journal of bacteriology 2009;191(15):4951-8.
2009: Hachmann Anna-Barbara; Angert Esther R; Helmann John D
Genetic analysis of factors affecting susceptibility of Bacillus subtilis to daptomycin.
Antimicrobial agents and chemotherapy 2009;53(4):1598-609.
2009: Eiamphungporn Warawan; Soonsanga Sumarin; Lee Jin-Won; Helmann John D
Oxidation of a single active site suffices for the functional inactivation of the dimeric Bacillus subtilis OhrR repressor in vitro.
Nucleic acids research 2009;37(4):1174-81.
2009: Nguyen Thi Thu Huyen; Eiamphungporn Warawan; Mäder Ulrike; Liebeke Manuel; Lalk Michael; Hecker Michael; Helmann John D; Antelmann Haike
Genome-wide responses to carbonyl electrophiles in Bacillus subtilis: control of the thiol-dependent formaldehyde dehydrogenase AdhA and cysteine proteinase YraA by the MerR-family regulator YraB (AdhR).
Molecular microbiology 2009;71(4):876-94.
2009: MacLellan Shawn R; Helmann John D; Antelmann Haike
The YvrI alternative sigma factor is essential for acid stress induction of oxalate decarboxylase in Bacillus subtilis.
Journal of bacteriology 2009;191(3):931-9.
2009: Eiamphungporn Warawan; Helmann John D
Extracytoplasmic function sigma factors regulate expression of the Bacillus subtilis yabE gene via a cis-acting antisense RNA.
Journal of bacteriology 2009;191(3):1101-5.
2009: Helmann John D
RNA polymerase: a nexus of gene regulation.
Methods (San Diego, Calif.) 2009;47(1):1-5.
2009: Maclellan Shawn R; Eiamphungporn Warawan; Helmann John D
ROMA: an in vitro approach to defining target genes for transcription regulators.
Methods (San Diego, Calif.) 2009;47(1):73-7.
2008: Salzberg Letal I; Helmann John D
Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.
Journal of bacteriology 2008;190(23):7797-807.
2008: Soonsanga Sumarin; Lee Jin-Won; Helmann John D
Conversion of Bacillus subtilis OhrR from a 1-Cys to a 2-Cys peroxide sensor.
Journal of bacteriology 2008;190(17):5738-45.
2008: Gaballa Ahmed; Antelmann Haike; Aguilar Claudio; Khakh Sukhjit K; Song Kyung-Bok; Smaldone Gregory T; Helmann John D
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteins.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11927-32.
2008: MacLellan Shawn R; Wecke Tina; Helmann John D
A previously unidentified sigma factor and two accessory proteins regulate oxalate decarboxylase expression in Bacillus subtilis.
Molecular microbiology 2008;69(4):954-67.
2008: Bordi Christophe; Butcher Bronwyn G; Shi Qiaojuan; Hachmann Anna-Barbara; Peters Joseph E; Helmann John D
In vitro mutagenesis of Bacillus subtilis by using a modified Tn7 transposon with an outward-facing inducible promoter.
Applied and environmental microbiology 2008;74(11):3419-25.
2008: Soonsanga Sumarin; Lee Jin-Won; Helmann John D
Oxidant-dependent switching between reversible and sacrificial oxidation pathways for Bacillus subtilis OhrR.
Molecular microbiology 2008;68(4):978-86.
2008: Gabriel Scott E; Miyagi Faith; Gaballa Ahmed; Helmann John D
Regulation of the Bacillus subtilis yciC gene and insights into the DNA-binding specificity of the zinc-sensing metalloregulator Zur.
Journal of bacteriology 2008;190(10):3482-8.
2008: Eiamphungporn Warawan; Helmann John D
The Bacillus subtilis sigma(M) regulon and its contribution to cell envelope stress responses.
Molecular microbiology 2008;67(4):830-48.
2007: Smaldone Gregory T; Helmann John D
CsoR regulates the copper efflux operon copZA in Bacillus subtilis.
Microbiology (Reading, England) 2007;153(Pt 12):4123-8.
2007: Butcher Bronwyn G; Lin Yi-Pin; Helmann John D
The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system.
Journal of bacteriology 2007;189(23):8616-25.
2007: Gaballa Ahmed; Helmann John D
Substrate induction of siderophore transport in Bacillus subtilis mediated by a novel one-component regulator.
Molecular microbiology 2007;66(1):164-73.
2007: Mascher Thorsten; Hachmann Anna-Barbara; Helmann John D
Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors.
Journal of bacteriology 2007;189(19):6919-27.
2007: Soonsanga Sumarin; Fuangthong Mayuree; Helmann John D
Mutational analysis of active site residues essential for sensing of organic hydroperoxides by Bacillus subtilis OhrR.
Journal of bacteriology 2007;189(19):7069-76.
2007: Helmann John D
Measuring metals with RNA.
Molecular cell 2007;27(6):859-60.
2007: Hochgräfe Falko; Mostertz Jörg; Pöther Dierk-Christoph; Becher Dörte; Helmann John D; Hecker Michael
S-cysteinylation is a general mechanism for thiol protection of Bacillus subtilis proteins after oxidative stress.
The Journal of biological chemistry 2007;282(36):25981-5.
2007: Jordan Sina; Rietkötter Eva; Strauch Mark A; Kalamorz Falk; Butcher Bronwyn G; Helmann John D; Mascher Thorsten
LiaRS-dependent gene expression is embedded in transition state regulation in Bacillus subtilis.
Microbiology (Reading, England) 2007;153(Pt 8):2530-40.
2007: Salzberg Letal I; Helmann John D
An antibiotic-inducible cell wall-associated protein that protects Bacillus subtilis from autolysis.
Journal of bacteriology 2007;189(13):4671-80.
2007: Lee Jin-Won; Helmann John D
Functional specialization within the Fur family of metalloregulators.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2007;20(3-4):485-99.
2007: Lee Jin-Won; Soonsanga Sumarin; Helmann John D
A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(21):8743-8.
2007: DeWitt Mark A; Kliegman Joseph I; Helmann John D; Brennan Richard G; Farrens David L; Glasfeld Arthur
The conformations of the manganese transport regulator of Bacillus subtilis in its metal-free state.
Journal of molecular biology 2007;365(5):1257-65.
2006: Mascher Thorsten; Helmann John D; Unden Gottfried
Stimulus perception in bacterial signal-transducing histidine kinases.
Microbiology and molecular biology reviews : MMBR 2006;70(4):910-38.
2006: Lee Jin-Won; Helmann John D
Biochemical characterization of the structural Zn2+ site in the Bacillus subtilis peroxide sensor PerR.
The Journal of biological chemistry 2006;281(33):23567-78.
2006: Jordan Sina; Junker Anja; Helmann John D; Mascher Thorsten
Regulation of LiaRS-dependent gene expression in bacillus subtilis: identification of inhibitor proteins, regulator binding sites, and target genes of a conserved cell envelope stress-sensing two-component system.
Journal of bacteriology 2006;188(14):5153-66.
2006: Ollinger Juliane; Song Kyung-Bok; Antelmann Haike; Hecker Michael; Helmann John D
Role of the Fur regulon in iron transport in Bacillus subtilis.
Journal of bacteriology 2006;188(10):3664-73.
2006: Butcher Bronwyn G; Helmann John D
Identification of Bacillus subtilis sigma-dependent genes that provide intrinsic resistance to antimicrobial compounds produced by Bacilli.
Molecular microbiology 2006;60(3):765-82.
2006: Lee Jin-Won; Helmann John D
The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation.
Nature 2006;440(7082):363-7.
2006: Kliegman Joseph I; Griner Sarah L; Helmann John D; Brennan Richard G; Glasfeld Arthur
Structural basis for the metal-selective activation of the manganese transport regulator of Bacillus subtilis.
Biochemistry 2006;45(11):3493-505.
2006: Choi Peter S; Naal Zeki; Moore Charles; Casado-Rivera Emerilis; Abruña Hector D; Helmann John D; Shapleigh James P
Assessing the impact of denitrifier-produced nitric oxide on other bacteria.
Applied and environmental microbiology 2006;72(3):2200-5.
2006: Helmann John D
Deciphering a complex genetic regulatory network: the Bacillus subtilis sigmaW protein and intrinsic resistance to antimicrobial compounds.
Science progress 2006;89(Pt 3-4):243-66.
2005: Hong Minsun; Fuangthong Mayuree; Helmann John D; Brennan Richard G
Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family.
Molecular cell 2005;20(1):131-41.
2005: Zhou Xiufen; He Xinyi; Liang Jingdan; Li Aiying; Xu Tiegang; Kieser Tobias; Helmann John D; Deng Zixin
A novel DNA modification by sulphur.
Molecular microbiology 2005;57(5):1428-38.
2005: Moore Charles M; Gaballa Ahmed; Hui Monica; Ye Rick W; Helmann John D
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Molecular microbiology 2005;57(1):27-40.
2005: Cao Min; Moore Charles M; Helmann John D
Bacillus subtilis paraquat resistance is directed by sigmaM, an extracytoplasmic function sigma factor, and is conferred by YqjL and BcrC.
Journal of bacteriology 2005;187(9):2948-56.
2005: Moore Charles M; Helmann John D
Metal ion homeostasis in Bacillus subtilis.
Current opinion in microbiology 2005;8(2):188-95.
2005: Golynskiy Misha V; Davis Talib C; Helmann John D; Cohen Seth M
Metal-induced structural organization and stabilization of the metalloregulatory protein MntR.
Biochemistry 2005;44(9):3380-9.
2004: Mascher Thorsten; Zimmer Sara L; Smith Terry-Ann; Helmann John D
Antibiotic-inducible promoter regulated by the cell envelope stress-sensing two-component system LiaRS of Bacillus subtilis.
Antimicrobial agents and chemotherapy 2004;48(8):2888-96.
2004: Moore Charles M; Nakano Michiko M; Wang Tao; Ye Rick W; Helmann John D
Response of Bacillus subtilis to nitric oxide and the nitrosating agent sodium nitroprusside.
Journal of bacteriology 2004;186(14):4655-64.
2004: Cao Min; Helmann John D
The Bacillus subtilis extracytoplasmic-function sigmaX factor regulates modification of the cell envelope and resistance to cationic antimicrobial peptides.
Journal of bacteriology 2004;186(4):1136-46.
2003: Gaballa Ahmed; Cao Min; Helmann John D
Two MerR homologues that affect copper induction of the Bacillus subtilis copZA operon.
Microbiology (Reading, England) 2003;149(Pt 12):3413-21.
2003: Mascher Thorsten; Margulis Neil G; Wang Tao; Ye Rick W; Helmann John D
Cell wall stress responses in Bacillus subtilis: the regulatory network of the bacitracin stimulon.
Molecular microbiology 2003;50(5):1591-604.
2003: Gaballa Ahmed; Helmann John D
Bacillus subtilis CPx-type ATPases: characterization of Cd, Zn, Co and Cu efflux systems.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2003;16(4):497-505.
2003: Lieser Scot A; Davis Talib C; Helmann John D; Cohen Seth M
DNA-binding and oligomerization studies of the manganese(II) metalloregulatory protein MntR from Bacillus subtilis.
Biochemistry 2003;42(43):12634-42.
2003: Fuangthong Mayuree; Helmann John D
Recognition of DNA by three ferric uptake regulator (Fur) homologs in Bacillus subtilis.
Journal of bacteriology 2003;185(21):6348-57.
2003: Guedon Emmanuel; Moore Charles M; Que Qiang; Wang Tao; Ye Rick W; Helmann John D
The global transcriptional response of Bacillus subtilis to manganese involves the MntR, Fur, TnrA and sigmaB regulons.
Molecular microbiology 2003;49(6):1477-91.
2003: Cao Min; Salzberg Letal; Tsai Ching Sung; Mascher Thorsten; Bonilla Carla; Wang Tao; Ye Rick W; Márquez-Magaña Leticia; Helmann John D
Regulation of the Bacillus subtilis extracytoplasmic function protein sigma(Y) and its target promoters.
Journal of bacteriology 2003;185(16):4883-90.
2003: Glasfeld Arthur; Guedon Emmanuel; Helmann John D; Brennan Richard G
Structure of the manganese-bound manganese transport regulator of Bacillus subtilis.
Nature structural biology 2003;10(8):652-7.
2003: Guedon Emmanuel; Helmann John D
Origins of metal ion selectivity in the DtxR/MntR family of metalloregulators.
Molecular microbiology 2003;48(2):495-506.
2003: Helmann John D; Wu Ming Fang Winston; Gaballa Ahmed; Kobel Phil A; Morshedi Maud M; Fawcett Paul; Paddon Chris
The global transcriptional response of Bacillus subtilis to peroxide stress is coordinated by three transcription factors.
Journal of bacteriology 2003;185(1):243-53.
2003: Helmann John D
Purification of Bacillus subtilis RNA polymerase and associated factors.
Methods in enzymology 2003;370():10-24.
2003: Paget Mark S B; Helmann John D
The sigma70 family of sigma factors.
Genome biology 2003;4(1):203.
2002: Gaballa Ahmed; Wang Tao; Ye Rick W; Helmann John D
Functional analysis of the Bacillus subtilis Zur regulon.
Journal of bacteriology 2002;184(23):6508-14.
2002: Helmann John D
OxyR: a molecular code for redox sensing?
Science's STKE : signal transduction knowledge environment 2002;2002(157):pe46.
2002: Cao Min; Helmann John D
Regulation of the Bacillus subtilis bcrC bacitracin resistance gene by two extracytoplasmic function sigma factors.
Journal of bacteriology 2002;184(22):6123-9.
2002: Baichoo Noel; Helmann John D
Recognition of DNA by Fur: a reinterpretation of the Fur box consensus sequence.
Journal of bacteriology 2002;184(21):5826-32.
2002: Helmann John D
Sensing nickel. NikRs with two pockets.
Chemistry & biology 2002;9(10):1055-7.
2002: Baichoo Noel; Wang Tao; Ye Rick; Helmann John D
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Molecular microbiology 2002;45(6):1613-29.
2002: Cao Min; Wang Tao; Ye Rick; Helmann John D
Antibiotics that inhibit cell wall biosynthesis induce expression of the Bacillus subtilis sigma(W) and sigma(M) regulons.
Molecular microbiology 2002;45(5):1267-76.
2002: Gaballa Ahmed; Helmann John D
A peroxide-induced zinc uptake system plays an important role in protection against oxidative stress in Bacillus subtilis.
Molecular microbiology 2002;45(4):997-1005.
2002: Mongkolsuk Skorn; Helmann John D
Regulation of inducible peroxide stress responses.
Molecular microbiology 2002;45(1):9-15.
2002: Qian Qiang; Lee Chien Y; Helmann John D; Strauch Mark A
AbrB is a regulator of the sigma(W) regulon in Bacillus subtilis.
FEMS microbiology letters 2002;211(2):219-23.
2002: Fuangthong Mayuree; Herbig Andrew F; Bsat Nada; Helmann John D
Regulation of the Bacillus subtilis fur and perR genes by PerR: not all members of the PerR regulon are peroxide inducible.
Journal of bacteriology 2002;184(12):3276-86.
2002: Fuangthong Mayuree; Helmann John D
The OhrR repressor senses organic hydroperoxides by reversible formation of a cysteine-sulfenic acid derivative.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(10):6690-5.
2002: Cao Min; Kobel Phil A; Morshedi Maud M; Wu Ming Fang Winston; Paddon Chris; Helmann John D
Defining the Bacillus subtilis sigma(W) regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches.
Journal of molecular biology 2002;316(3):443-57.
2002: Helmann John D
The extracytoplasmic function (ECF) sigma factors.
Advances in microbial physiology 2002;46():47-110.
2001: Helmann J D; Wu M F; Kobel P A; Gamo F J; Wilson M; Morshedi M M; Navre M; Paddon C
Global transcriptional response of Bacillus subtilis to heat shock.
Journal of bacteriology 2001;183(24):7318-28.
2001: Herbig A F; Helmann J D
Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA.
Molecular microbiology 2001;41(4):849-59.
2001: Atichartpongkul S; Loprasert S; Vattanaviboon P; Whangsuk W; Helmann J D; Mongkolsuk S
Bacterial Ohr and OsmC paralogues define two protein families with distinct functions and patterns of expression.
Microbiology (Reading, England) 2001;147(Pt 7):1775-82.
2001: Fuangthong M; Atichartpongkul S; Mongkolsuk S; Helmann J D
OhrR is a repressor of ohrA, a key organic hydroperoxide resistance determinant in Bacillus subtilis.
Journal of bacteriology 2001;183(14):4134-41.
2001: Cao M; Bernat B A; Wang Z; Armstrong R N; Helmann J D
FosB, a cysteine-dependent fosfomycin resistance protein under the control of sigma(W), an extracytoplasmic-function sigma factor in Bacillus subtilis.
Journal of bacteriology 2001;183(7):2380-3.
2001: Qiu J; Helmann J D
The -10 region is a key promoter specificity determinant for the Bacillus subtilis extracytoplasmic-function sigma factors sigma(X) and sigma(W).
Journal of bacteriology 2001;183(6):1921-7.
2000: Turner M S; Helmann J D
Mutations in multidrug efflux homologs, sugar isomerases, and antimicrobial biosynthesis genes differentially elevate activity of the sigma(X) and sigma(W) factors in Bacillus subtilis.
Journal of bacteriology 2000;182(18):5202-10.
2000: Que Q; Helmann J D
Manganese homeostasis in Bacillus subtilis is regulated by MntR, a bifunctional regulator related to the diphtheria toxin repressor family of proteins.
Molecular microbiology 2000;35(6):1454-68.
2000: Makui H; Roig E; Cole S T; Helmann J D; Gros P; Cellier M F
Identification of the Escherichia coli K-12 Nramp orthologue (MntH) as a selective divalent metal ion transporter.
Molecular microbiology 2000;35(5):1065-78.
1999: Qiu J; Helmann J D
Adenines at -11, -9 and -8 play a key role in the binding of Bacillus subtilis Esigma(A) RNA polymerase to -10 region single-stranded DNA.
Nucleic acids research 1999;27(23):4541-6.
1999: Bsat N; Helmann J D
Interaction of Bacillus subtilis Fur (ferric uptake repressor) with the dhb operator in vitro and in vivo.
Journal of bacteriology 1999;181(14):4299-307.
1999: López de Saro F J; Yoshikawa N; Helmann J D
Expression, abundance, and RNA polymerase binding properties of the delta factor of Bacillus subtilis.
The Journal of biological chemistry 1999;274(22):15953-8.
1999: Helmann J D; deHaseth P L
Protein-nucleic acid interactions during open complex formation investigated by systematic alteration of the protein and DNA binding partners.
Biochemistry 1999;38(19):5959-67.
1999: Helmann J D
Anti-sigma factors.
Current opinion in microbiology 1999;2(2):135-41.
1999: Huang X; Gaballa A; Cao M; Helmann J D
Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W.
Molecular microbiology 1999;31(1):361-71.
1998: Gaballa A; Helmann J D
Identification of a zinc-specific metalloregulatory protein, Zur, controlling zinc transport operons in Bacillus subtilis.
Journal of bacteriology 1998;180(22):5815-21.
1998: Huang X; Fredrick K L; Helmann J D
Promoter recognition by Bacillus subtilis sigmaW: autoregulation and partial overlap with the sigmaX regulon.
Journal of bacteriology 1998;180(15):3765-70.
1998: Bsat N; Herbig A; Casillas-Martinez L; Setlow P; Helmann J D
Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors.
Molecular microbiology 1998;29(1):189-98.
1998: Huang X; Helmann J D
Identification of target promoters for the Bacillus subtilis sigma X factor using a consensus-directed search.
Journal of molecular biology 1998;279(1):165-73.
1998: Chien Y; Helmann J D; Zinder S H
Interactions between the promoter regions of nitrogenase structural genes (nifHDK2) and DNA-binding proteins from N2- and ammonium-grown cells of the archaeon Methanosarcina barkeri 227.
Journal of bacteriology 1998;180(10):2723-8.
1997: Huang X; Lopez de Saro F J; Helmann J D
sigma factor mutations affecting the sequence-selective interaction of RNA polymerase with -10 region single-stranded DNA.
Nucleic acids research 1997;25(13):2603-9.
1997: Fredrick K; Helmann J D
RNA polymerase sigma factor determines start-site selection but is not required for upstream promoter element activation on heteroduplex (bubble) templates.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):4982-7.
1997: Huang X; Decatur A; Sorokin A; Helmann J D
The Bacillus subtilis sigma(X) protein is an extracytoplasmic function sigma factor contributing to survival at high temperature.
Journal of bacteriology 1997;179(9):2915-21.
1997: Chen Y F; Helmann J D
DNA-melting at the Bacillus subtilis flagellin promoter nucleates near -10 and expands unidirectionally.
Journal of molecular biology 1997;267(1):47-59.
1996: Fredrick K; Helmann J D
FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant.
Journal of bacteriology 1996;178(23):7010-3.
1996: Bsat N; Chen L; Helmann J D
Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes.
Journal of bacteriology 1996;178(22):6579-86.
1995: Chen L; Helmann J D
Bacillus subtilis MrgA is a Dps(PexB) homologue: evidence for metalloregulation of an oxidative-stress gene.
Molecular microbiology 1995;18(2):295-300.
1995: López de Saro F J; Woody A Y; Helmann J D
Structural analysis of the Bacillus subtilis delta factor: a protein polyanion which displaces RNA from RNA polymerase.
Journal of molecular biology 1995;252(2):189-202.
1995: Chen L; Keramati L; Helmann J D
Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8190-4.
1995: Helmann J D
Compilation and analysis of Bacillus subtilis sigma A-dependent promoter sequences: evidence for extended contact between RNA polymerase and upstream promoter DNA.
Nucleic acids research 1995;23(13):2351-60.
1995: Juang Y L; Helmann J D
Pathway of promoter melting by Bacillus subtilis RNA polymerase at a stable RNA promoter: effects of temperature, delta protein, and sigma factor mutations.
Biochemistry 1995;34(26):8465-73.
1995: Chen Y F; Helmann J D
The Bacillus subtilis flagellar regulatory protein sigma D: overproduction, domain analysis and DNA-binding properties.
Journal of molecular biology 1995;249(4):743-53.
1995: deHaseth P L; Helmann J D
Open complex formation by Escherichia coli RNA polymerase: the mechanism of polymerase-induced strand separation of double helical DNA.
Molecular microbiology 1995;16(5):817-24.
1995: Fredrick K; Caramori T; Chen Y F; Galizzi A; Helmann J D
Promoter architecture in the flagellar regulon of Bacillus subtilis: high-level expression of flagellin by the sigma D RNA polymerase requires an upstream promoter element.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2582-6.
1994: Rong J C; Helmann J D
Genetic and physiological studies of Bacillus subtilis sigma A mutants defective in promoter melting.
Journal of bacteriology 1994;176(17):5218-24.
1994: Aiyar S E; Juang Y L; Helmann J D; deHaseth P L
Mutations in sigma factor that affect the temperature dependence of transcription from a promoter, but not from a mismatch bubble in double-stranded DNA.
Biochemistry 1994;33(38):11501-6.
1994: Chen L; Helmann J D
The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.
Journal of bacteriology 1994;176(11):3093-101.
1994: Aiyar S E; Helmann J D; deHaseth P L
A mismatch bubble in double-stranded DNA suffices to direct precise transcription initiation by Escherichia coli RNA polymerase.
The Journal of biological chemistry 1994;269(18):13179-84.
1994: Rosario M M; Fredrick K L; Ordal G W; Helmann J D
Chemotaxis in Bacillus subtilis requires either of two functionally redundant CheW homologs.
Journal of bacteriology 1994;176(9):2736-9.
1994: Fredrick K L; Helmann J D
Dual chemotaxis signaling pathways in Bacillus subtilis: a sigma D-dependent gene encodes a novel protein with both CheW and CheY homologous domains.
Journal of bacteriology 1994;176(9):2727-35.
1994: Juang Y L; Helmann J D
The delta subunit of Bacillus subtilis RNA polymerase. An allosteric effector of the initiation and core-recycling phases of transcription.
Journal of molecular biology 1994;239(1):1-14.
1994: Juang Y L; Helmann J D
A promoter melting region in the primary sigma factor of Bacillus subtilis. Identification of functionally important aromatic amino acids.
Journal of molecular biology 1994;235(5):1470-88.
1993: Chen L; James L P; Helmann J D
Metalloregulation in Bacillus subtilis: isolation and characterization of two genes differentially repressed by metal ions.
Journal of bacteriology 1993;175(17):5428-37.
1992: Chen Y F; Helmann J D
Restoration of motility to an Escherichia coli fliA flagellar mutant by a Bacillus subtilis sigma factor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(11):5123-7.
1992: Wang L; Helmann J D; Winans S C
The A. tumefaciens transcriptional activator OccR causes a bend at a target promoter, which is partially relaxed by a plant tumor metabolite.
Cell 1992;69(4):659-67.
1991: Helmann J D
Alternative sigma factors and the regulation of flagellar gene expression.
Molecular microbiology 1991;5(12):2875-82.
1990: Márquez L M; Helmann J D; Ferrari E; Parker H M; Ordal G W; Chamberlin M J
Studies of sigma D-dependent functions in Bacillus subtilis.
Journal of bacteriology 1990;172(6):3435-43.
1990: Helmann J D; Ballard B T; Walsh C T
The MerR metalloregulatory protein binds mercuric ion as a tricoordinate, metal-bridged dimer.
Science (New York, N.Y.) 1990;247(4945):946-8.
1990: Helmann J D; Shewchuk L M; Walsh C T
Regulation of gene expression by mercury.
Advances in inorganic biochemistry 1990;8():33-61.
1989: Chater K F; Bruton C J; Plaskitt K A; Buttner M J; Méndez C; Helmann J D
The developmental fate of S. coelicolor hyphae depends upon a gene product homologous with the motility sigma factor of B. subtilis.
Cell 1989;59(1):133-43.
1989: Shewchuk L M; Helmann J D; Ross W; Park S J; Summers A O; Walsh C T
Transcriptional switching by the MerR protein: activation and repression mutants implicate distinct DNA and mercury(II) binding domains.
Biochemistry 1989;28(5):2340-4.
1989: Helmann J D; Wang Y; Mahler I; Walsh C T
Homologous metalloregulatory proteins from both gram-positive and gram-negative bacteria control transcription of mercury resistance operons.
Journal of bacteriology 1989;171(1):222-9.
1988: Helmann J D; Masiarz F R; Chamberlin M J
Isolation and characterization of the Bacillus subtilis sigma 28 factor.
Journal of bacteriology 1988;170(4):1560-7.
1988: Helmann J D; Márquez L M; Chamberlin M J
Cloning, sequencing, and disruption of the Bacillus subtilis sigma 28 gene.
Journal of bacteriology 1988;170(4):1568-74.
1988: Helmann J D; Chamberlin M J
Structure and function of bacterial sigma factors.
Annual review of biochemistry 1988;57():839-72.
1987: Helmann J D; Chamberlin M J
DNA sequence analysis suggests that expression of flagellar and chemotaxis genes in Escherichia coli and Salmonella typhimurium is controlled by an alternative sigma factor.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(18):6422-4.

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