Mark Dewhirst

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Brady Samuel L; Toncheva Greta; Dewhirst Mark W; Yoshizumi Terry T
Characterization of a 137Cs irradiator from a new perspective with modern dosimetric tools.
Viglianti Benjamin L; Lora-Michiels Michael; Poulson Jeanie M; Lan Lan; Yu Dahio; Sanders Linda; Craciunescu Oana; Vujaskovic Zeljko; Thrall Donald E; Macfall James; Charles Cecil H; Wong Terence; Dewhirst Mark W
Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy.
Kasper Amanda C; Moon Eui Jung; Hu Xiangqian; Park Yongho; Wooten Ceshea M; Kim Hyoungsu; Yang Weitao; Dewhirst Mark W; Hong Jiyong
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.

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All Publications

2009: Brady Samuel L; Toncheva Greta; Dewhirst Mark W; Yoshizumi Terry T
Characterization of a 137Cs irradiator from a new perspective with modern dosimetric tools.
Health physics 2009;97(3):195-205.
2009: Viglianti Benjamin L; Lora-Michiels Michael; Poulson Jeanie M; Lan Lan; Yu Dahio; Sanders Linda; Craciunescu Oana; Vujaskovic Zeljko; Thrall Donald E; Macfall James; Charles Cecil H; Wong Terence; Dewhirst Mark W
Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(15):4993-5001.
2009: Kasper Amanda C; Moon Eui Jung; Hu Xiangqian; Park Yongho; Wooten Ceshea M; Kim Hyoungsu; Yang Weitao; Dewhirst Mark W; Hong Jiyong
Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.
Bioorganic & medicinal chemistry letters 2009;19(14):3783-6.
2009: Kos Ivan; Rebouças Júlio S; DeFreitas-Silva Gilson; Salvemini Daniela; Vujaskovic Zeljko; Dewhirst Mark W; Spasojevic Ivan; Batinic-Haberle Ines
Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.
Free radical biology & medicine 2009;47(1):72-8.
2009: Hardee Matthew E; Dewhirst Mark W; Agarwal Nikita; Sorg Brian S
Novel imaging provides new insights into mechanisms of oxygen transport in tumors.
Current molecular medicine 2009;9(4):435-41.
2009: Pries Axel R; Cornelissen Annemiek J M; Sloot Anoek A; Hinkeldey Marlene; Dreher Matthew R; Höpfner Michael; Dewhirst Mark W; Secomb Timothy W
Structural adaptation and heterogeneity of normal and tumor microvascular networks.
PLoS computational biology 2009;5(5):e1000394.
2009: Cheng Kung-Shan; Yuan Yu; Li Zhen; Stauffer Paul R; Maccarini Paolo; Joines William T; Dewhirst Mark W; Das Shiva K
The performance of a reduced-order adaptive controller when used in multi-antenna hyperthermia treatments with nonlinear temperature-dependent perfusion.
Physics in medicine and biology 2009;54(7):1979-95.
2009: Palmer Gregory M; Viola Ronald J; Schroeder Thies; Yarmolenko Pavel S; Dewhirst Mark W; Ramanujam Nirmala
Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo.
Journal of biomedical optics 2009;14(2):024010.
2009: Skala Melissa C; Fontanella Andrew; Hendargo Hansford; Dewhirst Mark W; Izatt Joseph A
Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging.
Optics letters 2009;34(3):289-91.
2009: Kim Hyoungsu; Kasper Amanda C; Moon Eui Jung; Park Yongho; Wooten Ceshea M; Dewhirst Mark W; Hong Jiyong
Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins A and B.
Organic letters 2009;11(1):89-92.
2009: Hardee Matthew E; Eapen Rose J; Rabbani Zahid N; Dreher Matthew R; Marks Jeffrey; Blackwell Kimberly L; Dewhirst Mark W
Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors.
Cancer chemotherapy and pharmacology 2009;63(2):219-28.
2008: Snyder S A; Dewhirst M W; Hauck M L
The role of hypoxia in canine cancer.
Veterinary and comparative oncology 2008;6(4):213-23.
2008: Sonveaux Pierre; Végran Frédérique; Schroeder Thies; Wergin Melanie C; Verrax Julien; Rabbani Zahid N; De Saedeleer Christophe J; Kennedy Kelly M; Diepart Caroline; Jordan Bénédicte F; Kelley Michael J; Gallez Bernard; Wahl Miriam L; Feron Olivier; Dewhirst Mark W
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.
The Journal of clinical investigation 2008;118(12):3930-42.
2008: Viola Ronald J; Provenzale James M; Li Fang; Li Chuan-Yuan; Yuan Hong; Tashjian Jessica; Dewhirst Mark W
In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy.
AJR. American journal of roentgenology 2008;191(6):1779-84.
2008: Stein Rebecca A; Chang Ching-Yi; Kazmin Dmitri A; Way James; Schroeder Thies; Wergin Melanie; Dewhirst Mark W; McDonnell Donald P
Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer.
Cancer research 2008;68(21):8805-12.
2008: Mertyna Pawel; Dewhirst Mark W; Halpern Elkan; Goldberg Wallace; Goldberg S Nahum
Radiofrequency ablation: the effect of distance and baseline temperature on thermal dose required for coagulation.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(7):550-9.
2008: Kim E; Bowsher J; Thomas A S; Sakhalkar H; Dewhirst M; Oldham M
Improving the quantitative accuracy of optical-emission computed tomography by incorporating an attenuation correction: application to HIF1 imaging.
Physics in medicine and biology 2008;53(19):5371-83.
2008: Chen Qing; Krol Ava; Wright Alex; Needham David; Dewhirst Mark W; Yuan Fan
Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(6):475-82.
2008: Cárdenas-Navia Laura I; Mace Daniel; Richardson Rachel A; Wilson David F; Shan Siqing; Dewhirst Mark W
The pervasive presence of fluctuating oxygenation in tumors.
Cancer research 2008;68(14):5812-9.
2008: Schroeder Thies; Viglianti Benjamin L; Dewhirst Mark W
Low-intensity alternating electric fields: a potentially safe and effective treatment of cancer?
Onkologie 2008;31(7):357-8.
2008: Siddiqui Farzan; Avery Paul R; Li Chuan-Yuan; Zhang Xiuwu; LaRue Susan M; Dewhirst Mark W; Ullrich Robert L
Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy.
Cancer investigation 2008;26(6):553-61.
2008: Fitzhugh David J; Shan Siqing; Dewhirst Mark W; Hale Laura P
Bromelain treatment decreases neutrophil migration to sites of inflammation.
Clinical immunology (Orlando, Fla.) 2008;128(1):66-74.
2008: Dewhirst Mark W; Cao Yiting; Moeller Benjamin
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response.
Nature reviews. Cancer 2008;8(6):425-37.
2008: Manzoor Ashley A; Schroeder Thies; Dewhirst Mark W
One-stop-shop tumor imaging: buy hypoxia, get lactate free.
The Journal of clinical investigation 2008;118(5):1616-9.
2008: Sarraf-Yazdi Shiva; Mi Jing; Moeller Benjamin J; Niu Xilin; White Rebekah R; Kontos Christopher D; Sullenger Bruce A; Dewhirst Mark W; Clary Bryan M
Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer.
The Journal of surgical research 2008;146(1):16-23.
2008: Sarraf-Yazdi S; Mi J; Dewhirst M W; Clary B M
Use of bioluminescence imaging to detect enhanced hepatic and systemic tumor growth following partial hepatectomy in mice.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology 2008;34(4):476-81.
2008: Kirkpatrick John P; Dewhirst Mark W
Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder.
Radiation research 2008;169(3):350-4.
2008: Tashjian Jessica A; Dewhirst Mark W; Needham David; Viglianti Benjamin L
Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2008;24(1):79-90.
2008: Wong Terence Z; Lacy Jeffrey L; Petry Neil A; Hawk Thomas C; Sporn Thomas A; Dewhirst Mark W; Vlahovic Gordana
PET of hypoxia and perfusion with 62Cu-ATSM and 62Cu-PTSM using a 62Zn/62Cu generator.
AJR. American journal of roentgenology 2008;190(2):427-32.
2008: Sorg Brian S; Hardee Matthew E; Agarwal Nikita; Moeller Benjamin J; Dewhirst Mark W
Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors.
Journal of biomedical optics 2008;13(1):014026.
2008: Sathornsumetee Sith; Cao Yiting; Marcello Jennifer E; Herndon James E; McLendon Roger E; Desjardins Annick; Friedman Henry S; Dewhirst Mark W; Vredenburgh James J; Rich Jeremy N
Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(2):271-8.
2008: Mi Jing; Zhang Xiuwu; Rabbani Zahid N; Liu Yingmiao; Reddy Srinevas K; Su Zhen; Salahuddin Fawzia K; Viles Kristi; Giangrande Paloma H; Dewhirst Mark W; Sullenger Bruce A; Kontos Christopher D; Clary Bryan M
RNA aptamer-targeted inhibition of NF-kappa B suppresses non-small cell lung cancer resistance to doxorubicin.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(1):66-73.
2007: Rabbani Zahid N; Salahuddin Fawzia K; Yarmolenko Pavel; Batinic-Haberle Ines; Thrasher Bradley A; Gauter-Fleckenstein Benjamin; Dewhirst Mark W; Anscher Mitchell S; Vujaskovic Zeljko
Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.
Free radical research 2007;41(11):1273-82.
2007: Zennadi Rahima; Moeller Benjamin J; Whalen Erin J; Batchvarova Milena; Xu Ke; Shan Siqing; Delahunty Martha; Dewhirst Mark W; Telen Marilyn J
Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo.
Blood 2007;110(7):2708-17.
2007: Gridley Daila S; Makinde Adeola Y; Luo Xian; Rizvi Asma; Crapo James D; Dewhirst Mark W; Moeller Benjamin J; Pearlstein Robert D; Slater James M
Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model.
Anticancer research 2007;27(5A):3101-9.
2007: Vlahovic G; Ponce A M; Rabbani Z; Salahuddin F K; Zgonjanin L; Spasojevic I; Vujaskovic Z; Dewhirst M W
Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts.
British journal of cancer 2007;97(6):735-40.
2007: Moon Eui Jung; Brizel David M; Chi Jen-Tsan Ashley; Dewhirst Mark W
The potential role of intrinsic hypoxia markers as prognostic variables in cancer.
Antioxidants & redox signaling 2007;9(8):1237-94.
2007: Davis Bryce H; Schroeder Thies; Yarmolenko Pavel S; Guilak Farshid; Dewhirst Mark W; Taylor Doris A
An in vitro system to evaluate the effects of ischemia on survival of cells used for cell therapy.
Annals of biomedical engineering 2007;35(8):1414-24.
2007: Zhou Su-Min; Das Shiva K; Wang Zhiheng; Sun Xuejun; Dewhirst Mark; Yin Fang-Fang; Marks Lawrence B
Self-consistent tumor control probability and normal tissue complication probability models based on generalized EUD.
Medical physics 2007;34(7):2807-15.
2007: Das Shiva K; Zhou Sumin; Zhang Junan; Yin Fang-Fang; Dewhirst Mark W; Marks Lawrence B
Predicting lung radiotherapy-induced pneumonitis using a model combining parametric Lyman probit with nonparametric decision trees.
International journal of radiation oncology, biology, physics 2007;68(4):1212-21.
2007: Dewhirst Mark W; Cao Yiting; Li Chuan Yuan; Moeller Benjamin
Exploring the role of HIF-1 in early angiogenesis and response to radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2007;83(3):249-55.
2007: Huang Julie H; Cárdenas-Navia L Isabel; Caldwell Charles C; Plumb Troy J; Radu Caius G; Rocha Paulo N; Wilder Tuere; Bromberg Jonathan S; Cronstein Bruce N; Sitkovsky Michail; Dewhirst Mark W; Dustin Michael L
Requirements for T lymphocyte migration in explanted lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):7747-55.
2007: Moeller Benjamin J; Richardson Rachel A; Dewhirst Mark W
Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment.
Cancer metastasis reviews 2007;26(2):241-8.
2007: Chi Sulene L; Wahl Miriam L; Mowery Yvonne M; Shan Siqing; Mukhopadhyay Somnath; Hilderbrand Susana C; Kenan Daniel J; Lipes Barbara D; Johnson Carrie E; Marusich Michael F; Capaldi Roderick A; Dewhirst Mark W; Pizzo Salvatore V
Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase.
Cancer research 2007;67(10):4716-24.
2007: Dreher Matthew R; Liu Wenge; Michelich Charles R; Dewhirst Mark W; Chilkoti Ashutosh
Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors.
Cancer research 2007;67(9):4418-24.
2007: Cao Yiting; Sonveaux Pierre; Liu Shanling; Zhao Yulin; Mi Jing; Clary Bryan M; Li Chuan-Yuan; Kontos Christopher D; Dewhirst Mark W
Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth.
Cancer research 2007;67(8):3835-44.
2007: Li Fang; Sonveaux Pierre; Rabbani Zahid N; Liu Shanling; Yan Bin; Huang Qian; Vujaskovic Zeljko; Dewhirst Mark W; Li Chuan-Yuan
Regulation of HIF-1alpha stability through S-nitrosylation.
Molecular cell 2007;26(1):63-74.
2007: Sakhalkar H S; Dewhirst M; Oliver T; Cao Y; Oldham M
Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing.
Physics in medicine and biology 2007;52(8):2035-54.
2007: Dewhirst Mark W
Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting.
Cancer research 2007;67(3):854-5.
2007: Cárdenas-Navia L Isabel; Secomb Timothy W; Dewhirst Mark W
Effects of fluctuating oxygenation on tirapazamine efficacy: Theoretical predictions.
International journal of radiation oncology, biology, physics 2007;67(2):581-6.
2007: Rabbani Zahid N; Batinic-Haberle Ines; Anscher Mitchell S; Huang Jie; Day Brian J; Alexander Elaine; Dewhirst Mark W; Vujaskovic Zeljko
Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.
International journal of radiation oncology, biology, physics 2007;67(2):573-80.
2007: Oldham Mark; Sakhalkar Harshad; Wang Ying Min; Guo Pengyi; Oliver Tim; Bentley Rex; Vujaskovic Zeljko; Dewhirst Mark
Three-dimensional imaging of whole rodent organs using optical computed and emission tomography.
Journal of biomedical optics 2007;12(1):014009.
2007: Dewhirst Mark W; Navia Isabel Cardenas; Brizel David M; Willett Christopher; Secomb Timothy W
Multiple etiologies of tumor hypoxia require multifaceted solutions.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 1):375-7.
2007: Siddiqui Farzan; Li Chuan-Yuan; Larue Susan M; Poulson Jean M; Avery Paul R; Pruitt Amy F; Zhang Xiuwu; Ullrich Robert L; Thrall Donald E; Dewhirst Mark W; Hauck Marlene L
A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas.
Molecular cancer therapeutics 2007;6(1):380-9.
2007: Ponce Ana M; Viglianti Benjamin L; Yu Daohai; Yarmolenko Pavel S; Michelich Charles R; Woo Janet; Bally Marcel B; Dewhirst Mark W
Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects.
Journal of the National Cancer Institute 2007;99(1):53-63.
2007: Hardee Matthew E; Cao Yiting; Fu Ping; Jiang Xiaohong; Zhao Yulin; Rabbani Zahid N; Vujaskovic Zeljko; Dewhirst Mark W; Arcasoy Murat O
Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression.
PloS one 2007;2(6):e549.
2007: Cardenas-Navia L Isabel; Richardson Rachel A; Dewhirst Mark W
Targeting the molecular effects of a hypoxic tumor microenvironment.
Frontiers in bioscience : a journal and virtual library 2007;12():4061-78.
2006: Yan Bin; Wang Huili; Rabbani Zahid N; Zhao Yulin; Li Wenrong; Yuan Yuqing; Li Fang; Dewhirst Mark W; Li Chuan-Yuan
Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.
Cancer research 2006;66(24):11565-70.
2006: McGuire Sarah M; Zhou Sumin; Marks Lawrence B; Dewhirst Mark; Yin Fang-Fang; Das Shiva K
A methodology for using SPECT to reduce intensity-modulated radiation therapy (IMRT) dose to functioning lung.
International journal of radiation oncology, biology, physics 2006;66(5):1543-52.
2006: Bao Shideng; Wu Qiulian; McLendon Roger E; Hao Yueling; Shi Qing; Hjelmeland Anita B; Dewhirst Mark W; Bigner Darell D; Rich Jeremy N
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.
Nature 2006;444(7120):756-60.
2006: Kleiter Miriam M; Yu Daohai; Mohammadian Lenore A; Niehaus Nelsen; Spasojevic Ivan; Sanders Linda; Viglianti Benjamin L; Yarmolenko Pavel S; Hauck Marlene; Petry Neil A; Wong Terence Z; Dewhirst Mark W; Thrall Donald E
A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6800-7.
2006: Siddiqui Farzan; Ehrhart E J; Charles Brad; Chubb Laura; Li Chuan-Yuan; Zhang Xiuwu; Larue Susan M; Avery Paul R; Dewhirst Mark W; Ullrich Robert L
Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(7):587-606.
2006: Viglianti Benjamin L; Ponce Ana M; Michelich Charles R; Yu Daohai; Abraham Sheela A; Sanders Linda; Yarmolenko Pavel S; Schroeder Thies; MacFall James R; Barboriak Daniel P; Colvin O Michael; Bally Marcel B; Dewhirst Mark W
Chemodosimetry of in vivo tumor liposomal drug concentration using MRI.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(5):1011-8.
2006: Lora-Michiels Michaël; Yu Daohai; Sanders Linda; Poulson Jean M; Azuma Chieko; Case Beth; Vujaskovic Zeljko; Thrall Donald E; Charles H Cecil; Dewhirst Mark W
Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(19):5733-40.
2006: Vlahovic G; Rabbani Z N; Herndon J E; Dewhirst M W; Vujaskovic Z
Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation.
British journal of cancer 2006;95(8):1013-9.
2006: Anscher Mitchell S; Garst Jennifer; Marks Lawrence B; Larrier Nicole; Dunphy Frank; Herndon James E; Clough Robert; Marino Christine; Vujaskovic Zeljko; Zhou Sumin; Dewhirst Mark W; Shafman Timothy D; Crawford Jeffrey
Assessing the ability of the antiangiogenic and anticytokine agent thalidomide to modulate radiation-induced lung injury.
International journal of radiation oncology, biology, physics 2006;66(2):477-82.
2006: Oldham Mark; Sakhalkar Harshad; Oliver Tim; Wang Ying Min; Kirpatrick John; Cao Yiting; Badea Cristian; Johnson G Allan; Dewhirst Mark
Three-dimensional imaging of xenograft tumors using optical computed and emission tomography.
Medical physics 2006;33(9):3193-202.
2006: Oltean Sebastian; Sorg Brian S; Albrecht Todd; Bonano Vivian I; Brazas Robert M; Dewhirst Mark W; Garcia-Blanco Mariano A
Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(38):14116-21.
2006: Hicks Kevin O; Pruijn Frederik B; Secomb Timothy W; Hay Michael P; Hsu Richard; Brown J Martin; Denny William A; Dewhirst Mark W; Wilson William R
Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs.
Journal of the National Cancer Institute 2006;98(16):1118-28.
2006: Thrall D E; Larue S M; Pruitt A F; Case B; Dewhirst M W
Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(5):365-73.
2006: Yan B; Wang H; Wang H; Zhuo D; Li F; Kon T; Dewhirst M; Li C-Y
Apoptotic DNA fragmentation factor maintains chromosome stability in a P53-independent manner.
Oncogene 2006;25(39):5370-6.
2006: Shan Siqing; Flowers Clay; Peltz Cathy D; Sweet Heather; Maurer Norbert; Kwon Eun-Joo Gina; Krol Ave; Yuan Fan; Dewhirst Mark W
Preferential extravasation and accumulation of liposomal vincristine in tumor comparing to normal tissue enhances antitumor activity.
Cancer chemotherapy and pharmacology 2006;58(2):245-55.
2006: Hauck Marlene L; LaRue Susan M; Petros William P; Poulson Jean M; Yu Daohai; Spasojevic Ivan; Pruitt Amy F; Klein Allison; Case Beth; Thrall Donald E; Needham David; Dewhirst Mark W
Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):4004-10.
2006: Moeller B J; Dewhirst M W
HIF-1 and tumour radiosensitivity.
British journal of cancer 2006;95(1):1-5.
2006: Jackson I L; Batinic-Haberle I; Sonveaux P; Dewhirst M W; Vujaskovic Z
ROS production and angiogenic regulation by macrophages in response to heat therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(4):263-73.
2006: Yuan Hong; Schroeder Thies; Bowsher James E; Hedlund Laurence W; Wong Terence; Dewhirst Mark W
Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone).
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(6):989-98.
2006: Jones Ellen; Thrall Donald; Dewhirst Mark W; Vujaskovic Zeljko
Prospective thermal dosimetry: the key to hyperthermia's future.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(3):247-53.
2006: Ponce Ana M; Vujaskovic Zeljko; Yuan Fan; Needham David; Dewhirst Mark W
Hyperthermia mediated liposomal drug delivery.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(3):205-13.
2006: Kelly Patrick; Moeller Benjamin J; Juneja Juhi; Booden Michelle A; Der Channing J; Daaka Yehia; Dewhirst Mark W; Fields Timothy A; Casey Patrick J
The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8173-8.
2006: Jones Ellen; Alvarez Secord Angeles; Prosnitz Leonard R; Samulski Thaddeus V; Oleson James R; Berchuck Andrew; Clarke-Pearson Daniel; Soper John; Dewhirst Mark W; Vujaskovic Zeljko
Intra-peritoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(2):161-72.
2006: Siddiqui Farzan; Li Chuan-Yuan; Zhang Xiuwu; Larue Susan M; Dewhirst Mark W; Ullrich Robert L; Avery Paul R
Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2006;22(2):117-34.
2006: Dreher Matthew R; Liu Wenge; Michelich Charles R; Dewhirst Mark W; Yuan Fan; Chilkoti Ashutosh
Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers.
Journal of the National Cancer Institute 2006;98(5):335-44.
2006: Mi Jing; Sarraf-Yazdi Shiva; Zhang Xiuwu; Cao Yiting; Dewhirst Mark W; Kontos Christopher D; Li Chuan-Yuan; Clary Bryan M
A comparison of antiangiogenic therapies for the prevention of liver metastases.
The Journal of surgical research 2006;131(1):97-104.
2006: Kirkpatrick John P; Hardee Matthew E; Snyder Stacey A; Peltz Catherine M; Zhao Yulin; Brizel David M; Dewhirst Mark W; Blackwell Kimberly L
The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma.
Radiation research 2006;165(2):192-201.
2006: Hardee Matthew E; Rabbani Zahid N; Arcasoy Murat O; Kirkpatrick John P; Vujaskovic Zeljko; Dewhirst Mark W; Blackwell Kimberly L
Erythropoietin inhibits apoptosis in breast cancer cells via an Akt-dependent pathway without modulating in vivo chemosensitivity.
Molecular cancer therapeutics 2006;5(2):356-61.
2006: Lanzen Jennifer; Braun Rod D; Klitzman Bruce; Brizel David; Secomb Timothy W; Dewhirst Mark W
Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor.
Cancer research 2006;66(4):2219-23.
2006: Dressman Holly K; Hans Christopher; Bild Andrea; Olson John A; Rosen Eric; Marcom P Kelly; Liotcheva Vlayka B; Jones Ellen L; Vujaskovic Zeljko; Marks Jeffrey; Dewhirst Mark W; West Mike; Nevins Joseph R; Blackwell Kimberly
Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(3 Pt 1):819-26.
2006: Yan Bin; Wang Huili; Peng Yuanlin; Hu Ye; Wang He; Zhang Xiuwu; Chen Qi; Bedford Joel S; Dewhirst Mark W; Li Chuan-Yuan
A unique role of the DNA fragmentation factor in maintaining genomic stability.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1504-9.
2006: Hardee Matthew E; Arcasoy Murat O; Blackwell Kimberly L; Kirkpatrick John P; Dewhirst Mark W
Erythropoietin biology in cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(2):332-9.
2006: Batinic-Haberle Ines; Spasojevic Ivan; Stevens Robert D; Bondurant Bruce; Okado-Matsumoto Ayako; Fridovich Irwin; Vujaskovic Zeljko; Dewhirst Mark W
New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.
Dalton transactions (Cambridge, England : 2003) 2006;(4):617-24.
2006: Ko Sae Hee; Ueno Tomio; Yoshimoto Yasunori; Yoo Jin Soo; Abdel-Wahab Omar I; Abdel-Wahab Zeinab; Chu Edward; Pruitt Scott K; Friedman Henry S; Dewhirst Mark W; Tyler Douglas S
Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(1):289-97.
2006: Adams David J; Wahl Miriam L; Flowers James L; Sen Banalata; Colvin Michael; Dewhirst Mark W; Manikumar Govindarajan; Wani Mansukh C
Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient.
Cancer chemotherapy and pharmacology 2006;57(2):145-54.
2006: Tong Sheng; Chen Qing; Shan Si-Qing; Dewhirst Mark W; Yuan Fan
Quantitative comparison of the inhibitory effects of GW5638 and tamoxifen on angiogenesis in the cornea pocket assay.
Angiogenesis 2006;9(2):53-8.
2005: Dewhirst Mark W; Vujaskovic Zeljko; Jones Ellen; Thrall Donald
Re-setting the biologic rationale for thermal therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(8):779-90.
2005: Corry Peter M; Dewhirst Mark W
Thermal medicine, heat shock proteins and cancer.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(8):675-7.
2005: Hardee M E; Kirkpatrick J P; Shan S; Snyder S A; Vujaskovic Z; Rabbani Z N; Dewhirst M W; Blackwell K L
Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis.
British journal of cancer 2005;93(12):1350-5.
2005: Hart Justin P; Broadwater Gloria; Rabbani Zahid; Moeller Benjamin J; Clough Robert; Huang Dale; Sempowski Gregory A; Dewhirst Mark; Pizzo Salvatore V; Vujaskovic Zeljko; Anscher Mitchell S
Cytokine profiling for prediction of symptomatic radiation-induced lung injury.
International journal of radiation oncology, biology, physics 2005;63(5):1448-54.
2005: Das Shiva K; Macfall James; McCauley Robert; Craciunescu Oana; Dewhirst Mark W; Samulski Thaddeus V
Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(7):657-67.
2005: Moeller Benjamin J; Dewhirst Mark W
In regard to Arvold et al. (Int J Radiat Oncol Biol Phys 2005;62:207-212).
International journal of radiation oncology, biology, physics 2005;63(3):970-1; author reply 971.
2005: Sorg Brian S; Peltz Cathryn D; Klitzman Bruce; Dewhirst Mark W
Method for improved accuracy in endogenous urea recovery marker calibrations for microdialysis in tumors.
Journal of pharmacological and toxicological methods 2005;52(3):341-9.
2005: Jones Ellen L; Prosnitz Leonard R; Dewhirst Mark W; Vujaskovic Zeljko; Samulski Thaddeus V; Oleson James R; Yu Daohi; Myerson Robert J; Moros Eduardo G; Hurwitz Mark D; Bull Joan M C
In regard to Vasanathan et al. (Int J Radiat Oncol Biol Phys 2005;61:145-153).
International journal of radiation oncology, biology, physics 2005;63(2):644.
2005: Moeller Benjamin J; Batinic-Haberle Ines; Spasojevic Ivan; Rabbani Zahid N; Anscher Mitchell S; Vujaskovic Zeljko; Dewhirst Mark W
A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.
International journal of radiation oncology, biology, physics 2005;63(2):545-52.
2005: Provenzale James M; Mukundan Srinivasan; Dewhirst Mark
The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.
AJR. American journal of roentgenology 2005;185(3):763-7.
2005: Kim Seok Jin; Rabbani Zahid N; Dewhirst Mark W; Vujaskovic Zeljko; Vollmer Robin T; Schreiber Ernst-Gilbert; Oosterwijk Egbert; Kelley Michael J
Expression of HIF-1alpha, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2005;49(3):325-35.
2005: Moeller Benjamin J; Dreher Matthew R; Rabbani Zahid N; Schroeder Thies; Cao Yiting; Li Chuan Y; Dewhirst Mark W
Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity.
Cancer cell 2005;8(2):99-110.
2005: Sorg Brian S; Moeller Benjamin J; Donovan Owen; Cao Yiting; Dewhirst Mark W
Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development.
Journal of biomedical optics 2005;10(4):44004.
2005: Thrall Donald E; LaRue Susan M; Yu Daohai; Samulski Thaddeus; Sanders Linda; Case Beth; Rosner Gary; Azuma Chieko; Poulson Jeannie; Pruitt Amy F; Stanley Wilma; Hauck Marlene L; Williams Laurel; Hess Paul; Dewhirst Mark W
Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5206-14.
2005: Cao Yiting; Li Chuan-Yuan; Moeller Benjamin J; Yu Daohai; Zhao Yulin; Dreher Matthew R; Shan Siqing; Dewhirst Mark W
Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation.
Cancer research 2005;65(13):5498-505.
2005: Hahn C A; Jones E L; Blivin J L; Sanders L L; Yu D; Dewhirst M W; Secord A A; Prosnitz L R
Prospective assessment of quality of life in ovarian cancer patients receiving whole abdomen hyperthermia and liposomal doxorubicin.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(4):349-57.
2005: Alvarez Secord A; Jones E L; Hahn C A; Petros W P; Yu D; Havrilesky L J; Soper J T; Berchuck A; Spasojevic I; Clarke-Pearson D L; Prosnitz L R; Dewhirst M W
Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancer.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2005;21(4):333-47.
2005: Schroeder Thies; Yuan Hong; Viglianti Benjamin L; Peltz Cathryn; Asopa Shubha; Vujaskovic Zeljko; Dewhirst Mark W
Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat.
Cancer research 2005;65(12):5163-71.
2005: Sonveaux Pierre; Kaz Andrew M; Snyder Stacey A; Richardson Rachel A; Cárdenas-Navia L Isabel; Braun Rodney D; Pawloski John R; Tozer Gillian M; Bonaventura Joseph; McMahon Timothy J; Stamler Jonathan S; Dewhirst Mark W
Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.
Circulation research 2005;96(10):1119-26.
2005: Jones Ellen L; Oleson James R; Prosnitz Leonard R; Samulski Thaddeus V; Vujaskovic Zeljko; Yu Daohai; Sanders Linda L; Dewhirst Mark W
Randomized trial of hyperthermia and radiation for superficial tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(13):3079-85.
2005: Anscher Mitchell S; Chen Liguang; Rabbani Zahid; Kang Song; Larrier Nicole; Huang Hong; Samulski Thaddeus V; Dewhirst Mark W; Brizel David M; Folz Rodney J; Vujaskovic Zeljko
Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy.
International journal of radiation oncology, biology, physics 2005;62(1):255-9.
2005: Mazooz Galit; Mehlman Tevie; Lai Thung-Shen; Greenberg Charles S; Dewhirst Mark W; Neeman Michal
Development of magnetic resonance imaging contrast material for in vivo mapping of tissue transglutaminase activity.
Cancer research 2005;65(4):1369-75.
2005: Dewhirst Mark W; Poulson Jean M; Yu Daohai; Sanders Linda; Lora-Michiels Michaël; Vujaskovic Zeljko; Jones Ellen L; Samulski Thaddeus V; Powers Barbara E; Brizel David M; Prosnitz Leonard R; Charles H Cecil
Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy.
International journal of radiation oncology, biology, physics 2005;61(2):480-91.
2005: Das Shiva K; Baydush Alan H; Zhou Sumin; Miften Moyed; Yu Xiaoli; Craciunescu Oana; Oldham Mark; Light Kim; Wong Terence; Blazing Michael; Borges-Neto Salvador; Dewhirst Mark W; Marks Lawrence B
Predicting radiotherapy-induced cardiac perfusion defects.
Medical physics 2005;32(1):19-27.
2005: Peltz Cathryn; Schroeder Thies; Dewhirst Mark W
Monitoring metabolite gradients in the blood, liver, and tumor after induced hyperglycemia in rats with R3230 flank tumors using microdialysis and bioluminescence imaging.
Advances in experimental medicine and biology 2005;566():343-8.
2005: Biaglow John; Dewhirst Mark; Leeper Dennis; Burd Randy; Tuttle Steve
Factors controlling oxygen utilization.
Advances in experimental medicine and biology 2005;566():317-23.
2005: Rabbani Zahid N; Anscher Mitchell S; Folz Rodney J; Archer Emerald; Huang Hong; Chen Liguang; Golson Maria L; Samulski Thaddeus S; Dewhirst Mark W; Vujaskovic Zeljko
Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity.
BMC cancer 2005;5():59.
2004: Kim Seok Jin; Rabbani Zahid N; Vollmer Robin T; Schreiber Ernst-Gilbert; Oosterwijk Egbert; Dewhirst Mark W; Vujaskovic Zeljko; Kelley Michael J
Carbonic anhydrase IX in early-stage non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):7925-33.
2004: Secomb Timothy W; Hsu Richard; Park Eric Y H; Dewhirst Mark W
Green's function methods for analysis of oxygen delivery to tissue by microvascular networks.
Annals of biomedical engineering 2004;32(11):1519-29.
2004: Zhang Xiuwu; Kon Takashi; Wang He; Li Fang; Huang Qian; Rabbani Zahid N; Kirkpatrick John P; Vujaskovic Zeljko; Dewhirst Mark W; Li Chuan-Yuan
Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha.
Cancer research 2004;64(22):8139-42.
2004: Dreher Matthew R; Elas Martyna; Ichikawa Kazuhiro; Barth Eugene D; Chilkoti Ashutosh; Rosen Gerald M; Halpern Howard J; Dewhirst Mark
Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry.
Medical physics 2004;31(10):2755-62.
2004: Chen Qing; Tong Sheng; Dewhirst Mark W; Yuan Fan
Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome.
Molecular cancer therapeutics 2004;3(10):1311-7.
2004: Dewhirst Mark W; Richardson Rachel; Cardenas-Navia Isabel; Cao Yiting
The relationship between the tumor physiologic microenvironment and angiogenesis.
Hematology/oncology clinics of North America 2004;18(5):973-90, vii.
2004: Abdel-Wahab Omar I; Grubbs Elizabeth; Viglianti Benjamin L; Cheng Tsung-Yen; Ueno Tomio; Ko SaeHee; Rabbani Zahid; Curtis Simon; Pruitt Scott K; Dewhirst Mark W; Tyler Doug S
The role of hyperthermia in regional alkylating agent chemotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5919-29.
2004: Cárdenas-Navia L Isabel; Yu Daohai; Braun Rod D; Brizel David M; Secomb Timothy W; Dewhirst Mark W
Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing.
Cancer research 2004;64(17):6010-7.
2004: Moeller Benjamin J; Dewhirst Mark W
Raising the bar: how HIF-1 helps determine tumor radiosensitivity.
Cell cycle (Georgetown, Tex.) 2004;3(9):1107-10.
2004: Poulson J M; Vujaskovic Z; Gaskin A A; Larue S M; Meyer R E; Prescott D M; Samulski T V; Thrall D E; Dewhirst M W
Effect of calcitonin gene related peptide vs sodium nitroprusside to increase temperature in spontaneous canine tumours during local hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2004;20(5):477-89.
2004: Sarraf-Yazdi Shiva; Mi Jing; Dewhirst Mark W; Clary Bryan M
Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice.
The Journal of surgical research 2004;120(2):249-55.
2004: Moeller Benjamin J; Cao Yiting; Vujaskovic Zeljko; Li Chuan Y; Haroon Zishan A; Dewhirst Mark W
The relationship between hypoxia and angiogenesis.
Seminars in radiation oncology 2004;14(3):215-21.
2004: Jones Ellen L; Prosnitz Leonard R; Dewhirst Mark W; Marcom P Kelly; Hardenbergh Patricia H; Marks Lawrence B; Brizel David M; Vujaskovic Zeljko
Thermochemoradiotherapy improves oxygenation in locally advanced breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4287-93.
2004: Blackwell Kimberly; Hurwitz Herbert; Liebérman Grazyna; Novotny William; Snyder Stacey; Dewhirst Mark; Greenberg Charles
Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma.
Cancer 2004;101(1):77-82.
2004: Kirkpatrick J P; Cárdenas-Navia L I; Dewhirst M W
Predicting the effect of temporal variations in PO2 on tumor radiosensitivity.
International journal of radiation oncology, biology, physics 2004;59(3):822-33.
2004: Das S K; Miften M M; Zhou S; Bell M; Munley M T; Whiddon C S; Craciunescu O; Baydush A H; Wong T; Rosenman J G; Dewhirst M W; Marks L B
Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions.
Medical physics 2004;31(6):1452-61.
2004: Blackwell Kimberly L; Dewhirst Mark W; Liotcheva Vlayka; Snyder Stacey; Broadwater Gloria; Bentley Rex; Lal Anita; Riggins Gregory; Anderson Steve; Vredenburgh Jim; Proia Alan; Harris Lyndsay N
HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4083-8.
2004: Viglianti Benjamin L; Abraham Sheela A; Michelich Charles R; Yarmolenko Pavel S; MacFall James R; Bally Marcel B; Dewhirst Mark W
In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;51(6):1153-62.
2004: Secomb Timothy W; Hsu Richard; Dewhirst Mark W
Synergistic effects of hyperoxic gas breathing and reduced oxygen consumption on tumor oxygenation: a theoretical model.
International journal of radiation oncology, biology, physics 2004;59(2):572-8.
2004: Moeller Benjamin J; Cao Yiting; Li Chuan Y; Dewhirst Mark W
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.
Cancer cell 2004;5(5):429-41.
2004: Ward Erika R; Hedlund Laurence W; Kurylo William C; Wheeler Charles T; Cofer Gary P; Dewhirst Mark W; Marks Lawrence B; Vujaskovic Zeljko
Proton and hyperpolarized helium magnetic resonance imaging of radiation-induced lung injury in rats.
International journal of radiation oncology, biology, physics 2004;58(5):1562-9.
2004: Shan Siqing; Robson Nicole D; Cao Yiting; Qiao Tong; Li Chuan Y; Kontos Christopher D; Garcia-Blanco Mariano; Dewhirst Mark W
Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(2):326-8.
2004: Peters Kevin G; Kontos Christopher D; Lin P Charles; Wong Adrianne L; Rao Prema; Huang Liwen; Dewhirst Mark W; Sankar Sabita
Functional significance of Tie2 signaling in the adult vasculature.
Recent progress in hormone research 2004;59():51-71.
2003: Eu Jerry P; Hare Joshua M; Hess Douglas T; Skaf Michel; Sun Junhui; Cardenas-Navina Isabella; Sun Qi-An; Dewhirst Mark; Meissner Gerhard; Stamler Jonathan S
Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15229-34.
2003: Kang Song K; Rabbani Zahid N; Folz Rodney J; Golson Maria L; Huang Hong; Yu Daohai; Samulski Thaddeus S; Dewhirst Mark W; Anscher Mitchell S; Vujaskovic Zeljko
Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury.
International journal of radiation oncology, biology, physics 2003;57(4):1056-66.
2003: Rosen Eric L; Blackwell Kimberly L; Baker Jay A; Soo Mary Scott; Bentley Rex C; Yu Daohai; Samulski Thaddeus V; Dewhirst Mark W
Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy.
AJR. American journal of roentgenology 2003;181(5):1275-82.
2003: Blackwell Kimberly L; Kirkpatrick John P; Snyder Stacey A; Broadwater Gloria; Farrell Francis; Jolliffe Linda; Brizel David M; Dewhirst Mark W
Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin.
Cancer research 2003;63(19):6162-5.
2003: Dewhirst Mark W; Sneed Penny K
Those in gene therapy should pay closer attention to lessons from hyperthermia.
International journal of radiation oncology, biology, physics 2003;57(2):597-9; author reply 599-600.
2003: Vujaskovic Z; Rosen E L; Blackwell K L; Jones E L; Brizel D M; Prosnitz L R; Samulski T V; Dewhirst M W
Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatment.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(5):498-506.
2003: Flowers James L; Hoffman Robert M; Driscoll Timothy A; Wall Monroe E; Wani Mansukh C; Manikumar Govindarajan; Friedman Henry S; Dewhirst Mark; Colvin O Michael; Adams David J
The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH.
Cancer chemotherapy and pharmacology 2003;52(3):253-61.
2003: Erickson Kristian; Braun Rod D; Yu Daohai; Lanzen Jennifer; Wilson David; Brizel David M; Secomb Timothy W; Biaglow John E; Dewhirst Mark W
Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation.
Cancer research 2003;63(15):4705-12.
2003: Voss Miranda; Pinheiro Jose; Reynolds James; Greene Rebecca; Dewhirst Mark; Vaslef Steven N; Clary Erik; Eubanks W Steve
Endoscopic components separation for abdominal compartment syndrome.
American journal of surgery 2003;186(2):158-63.
2003: Nair Smita; Boczkowski David; Moeller Benjamin; Dewhirst Mark; Vieweg Johannes; Gilboa Eli
Synergy between tumor immunotherapy and antiangiogenic therapy.
Blood 2003;102(3):964-71.
2003: Jones Ellen L; Samulski Thaddeus V; Dewhirst Mark W; Alvarez-Secord Angeles; Berchuck Andrew; Clarke-Pearson Daniel; Havrilesky Laura J; Soper John; Prosnitz Leonard R
A pilot Phase II trial of concurrent radiotherapy, chemotherapy, and hyperthermia for locally advanced cervical carcinoma.
Cancer 2003;98(2):277-82.
2003: Lockhart A Craig; Braun Rod D; Yu Daohai; Ross Joel R; Dewhirst Mark W; Klitzman Bruce; Yuan Fan; Grichnik James M; Proia Alan D; Conway Delina A; Mann Gretchen; Hurwitz Herbert I
A clinical model of dermal wound angiogenesis.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2003;11(4):306-13.
2003: Goldstein L S; Dewhirst M W; Repacholi M; Kheifets L
Summary, conclusions and recommendations: adverse temperature levels in the human body.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(3):373-84.
2003: Dewhirst M W; Viglianti B L; Lora-Michiels M; Hanson M; Hoopes P J
Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(3):267-94.
2003: Dewhirst M W; Lora-Michiels M; Viglianti B L; Dewey W C; Repacholi M
Carcinogenic effects of hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(3):236-51.
2003: White Rebekah R; Shan Siqing; Rusconi Christopher P; Shetty Geetha; Dewhirst Mark W; Kontos Christopher D; Sullenger Bruce A
Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5028-33.
2003: Amin Khalid; Li Jie; Chao Wan Ru; Dewhirst Mark W; Haroon Zishan A
Dietary glycine inhibits angiogenesis during wound healing and tumor growth.
Cancer biology & therapy 2003;2(2):173-8.
2003: Shan Siqing; Sorg Brian; Dewhirst Mark W
A novel rodent mammary window of orthotopic breast cancer for intravital microscopy.
Microvascular research 2003;65(2):109-17.
2003: Zhang Xiuwu; Li Yongping; Huang Qian; Wang He; Yan Bin; Dewhirst Mark W; Li Chuan-Yuan
Increased resistance of tumor cells to hyperthermia mediated by integrin-linked kinase.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):1155-60.
2003: Krol A; Dewhirst M W; Yuan F
Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2003;19(2):154-64.
2003: Kirkpatrick John P; Brizel David M; Dewhirst Mark W
A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics.
Radiation research 2003;159(3):336-44.
2003: Lockhart A Craig; Braun Rod D; Yu Daohai; Ross Joel R; Dewhirst Mark W; Humphrey Jeffrey S; Thompson Seth; Williams Kathleen M; Klitzman Bruce; Yuan Fan; Grichnik James M; Proia Alan D; Conway Delina A; Hurwitz Herbert I
Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):586-93.
2003: Lee Intae; Glickson Jerry D; Dewhirst Mark W; Leeper Dennis B; Burd Randy; Poptani Harish; Nadal Lydie; McKenna W Gillies; Biaglow John E
Effect of mild hyperglycemia +/- meta-iodo-benzylguanidine on the radiation response of R3230 Ac tumors.
Advances in experimental medicine and biology 2003;530():177-86.
2003: Biaglow John E; Lee Intae; Donahue Jerry; Held Kathy; Mieyal John; Dewhirst Mark; Tuttle Steve
Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma.
Advances in experimental medicine and biology 2003;530():153-64.
2003: Richardson Rachel A; Dewhirst Mark W
The effect of nicotinamide & hyperoxic gases on blood glucose.
Advances in experimental medicine and biology 2003;510():375-8.
2003: Dewhirst Mark W
Mechanisms underlying hypoxia development in tumors.
Advances in experimental medicine and biology 2003;510():51-6.
2003: Cárdenas-Navia L Isabel; Braun Rod; Lewis Kristina; Dewhirst Mark
Comparison of fluctuations of oxygen tension in FSA, 9L, and R3230AC tumors in rats.
Advances in experimental medicine and biology 2003;510():7-12.
2002: Li C Y; Dewhirst M W
Hyperthermia-regulated immunogene therapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002;18(6):586-96.
2002: Zeman Elaine M; Dynlacht Joseph R; Rosenstein Barry S; Dewhirst Mark W;
Toward a national consensus: teaching radiobiology to radiation oncology residents.
International journal of radiation oncology, biology, physics 2002;54(3):861-72.
2002: Wong Christopher W; Song Chun; Grimes Maggie M; Fu Weili; Dewhirst Mark W; Muschel Ruth J; Al-Mehdi Abu-Bakr
Intravascular location of breast cancer cells after spontaneous metastasis to the lung.
The American journal of pathology 2002;161(3):749-53.
2002: Vujaskovic Zeljko; Batinic-Haberle Ines; Rabbani Zahid N; Feng Qin-fu; Kang Song K; Spasojevic Ivan; Samulski Thaddeus V; Fridovich Irwin; Dewhirst Mark W; Anscher Mitchell S
A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.
Free radical biology & medicine 2002;33(6):857-63.
2002: Kavanagh Brian D; Secomb Timothy W; Hsu Richard; Lin Peck Sun; Venitz Jurgen; Dewhirst Mark W
A theoretical model for the effects of reduced hemoglobin-oxygen affinity on tumor oxygenation.
International journal of radiation oncology, biology, physics 2002;53(1):172-9.
2002: Dynlacht Joseph R; Dewhirst Mark W; Hall Eric J; Rosenstein Barry S; Zeman Elaine M
Toward a consensus on radiobiology teaching to radiation oncology residents.
Radiation research 2002;157(5):599-606.
2002: Hale Laura P; Braun Rod D; Gwinn William M; Greer Paula K; Dewhirst Mark W
Hypoxia in the thymus: role of oxygen tension in thymocyte survival.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1467-77.
2002: Haroon Zishan A; Amin Khalid; Saito Wilfred; Wilson William; Greenberg Charles S; Dewhirst Mark W
SU5416 delays wound healing through inhibition of TGF-beta 1 activation.
Cancer biology & therapy 2002;1(2):121-6.
2002: Dewhirst Mark W; Shan S; Cao Yiting; Moeller Benjamin; Yuan Fan; Li Chuan-Yuan
Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals.
Disease markers 2002;18(5-6):293-311.
2001: Needham D; Dewhirst M W
The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors.
Advanced drug delivery reviews 2001;53(3):285-305.
2001: Pogue B W; Braun R D; Lanzen J L; Erickson C; Dewhirst M W
Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin.
Photochemistry and photobiology 2001;74(5):700-6.
2001: Lohr F; Huang Q; Hu K; Dewhirst M W; Li C Y
Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(11):3625-8.
2001: Walenta S; Snyder S; Haroon Z A; Braun R D; Amin K; Brizel D; Mueller-Klieser W; Chance B; Dewhirst M W
Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model.
International journal of radiation oncology, biology, physics 2001;51(3):840-8.
2001: Ettinger S N; Poellmann C C; Wisniewski N A; Gaskin A A; Shoemaker J S; Poulson J M; Dewhirst M W; Klitzman B
Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis.
Cancer research 2001;61(21):7964-70.
2001: Snyder S A; Lanzen J L; Braun R D; Rosner G; Secomb T W; Biaglow J; Brizel D M; Dewhirst M W
Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone.
International journal of radiation oncology, biology, physics 2001;51(2):494-506.
2001: Brizel D M; Schroeder T; Scher R L; Walenta S; Clough R W; Dewhirst M W; Mueller-Klieser W
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer.
International journal of radiation oncology, biology, physics 2001;51(2):349-53.
2001: Lal A; Peters H; St Croix B; Haroon Z A; Dewhirst M W; Strausberg R L; Kaanders J H; van der Kogel A J; Riggins G J
Transcriptional response to hypoxia in human tumors.
Journal of the National Cancer Institute 2001;93(17):1337-43.
2001: Tozer G M; Prise V E; Wilson J; Cemazar M; Shan S; Dewhirst M W; Barber P R; Vojnovic B; Chaplin D J
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability.
Cancer research 2001;61(17):6413-22.
2001: Shan S; Lockhart A C; Saito W Y; Knapp A M; Laderoute K R; Dewhirst M W
The novel tubulin-binding drug BTO-956 inhibits R3230AC mammary carcinoma growth and angiogenesis in Fischer 344 rats.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2590-6.
2001: Meyer D E; Shin B C; Kong G A; Dewhirst M W; Chilkoti A
Drug targeting using thermally responsive polymers and local hyperthermia.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):213-24.
2001: Maguire P D; Samulski T V; Prosnitz L R; Jones E L; Rosner G L; Powers B; Layfield L W; Brizel D M; Scully S P; Harrelson J M; Dewhirst M W
A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2001;17(4):283-90.
2001: Vujaskovic Z; Anscher M S; Feng Q F; Rabbani Z N; Amin K; Samulski T S; Dewhirst M W; Haroon Z A
Radiation-induced hypoxia may perpetuate late normal tissue injury.
International journal of radiation oncology, biology, physics 2001;50(4):851-5.
2001: Braun R D; Lanzen J L; Snyder S A; Dewhirst M W
Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents.
American journal of physiology. Heart and circulatory physiology 2001;280(6):H2533-44.
2001: Neeman M; Dafni H; Bukhari O; Braun R D; Dewhirst M W
In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2001;45(5):887-98.
2001: Braun R D; Lanzen J L; Turnage J A; Rosner G; Dewhirst M W
Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats.
Radiation research 2001;155(5):724-33.
2001: Lohr F; Lo D Y; Zaharoff D A; Hu K; Zhang X; Li Y; Zhao Y; Dewhirst M W; Yuan F; Li C Y
Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation.
Cancer research 2001;61(8):3281-4.
2001: Kong G; Braun R D; Dewhirst M W
Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature.
Cancer research 2001;61(7):3027-32.
2001: Connor C E; Norris J D; Broadwater G; Willson T M; Gottardis M M; Dewhirst M W; McDonnell D P
Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor.
Cancer research 2001;61(7):2917-22.
2001: Meyer D E; Kong G A; Dewhirst M W; Zalutsky M R; Chilkoti A
Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.
Cancer research 2001;61(4):1548-54.
2001: Li C Y; Little J B; Hu K; Zhang W; Zhang L; Dewhirst M W; Huang Q
Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures.
Cancer research 2001;61(2):428-32.
2001: Neeman M; Provenzale J M; Dewhirst M W
Magnetic resonance imaging applications in the evaluation of tumor angiogenesis.
Seminars in radiation oncology 2001;11(1):70-82.
2000: Kong G; Anyarambhatla G; Petros W P; Braun R D; Colvin O M; Needham D; Dewhirst M W
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release.
Cancer research 2000;60(24):6950-7.
2000: Lohr F; Hu K; Huang Q; Zhang L; Samulski T V; Dewhirst M W; Li C Y
Enhancement of radiotherapy by hyperthermia-regulated gene therapy.
International journal of radiation oncology, biology, physics 2000;48(5):1513-8.
2000: Zhang X Y; Luck J; Dewhirst M W; Yuan F
Interstitial hydraulic conductivity in a fibrosarcoma.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H2726-34.
2000: Poulson J M; Dewhirst M W; Gaskin A A; Vujaskovic Z; Samulski T V; Prescott D M; Meyer R E; Page R L; Thrall D E
Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs.
In vivo (Athens, Greece) 2000;14(6):709-14.
2000: Blackwell K L; Haroon Z A; Shan S; Saito W; Broadwater G; Greenberg C S; Dewhirst M W
Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4359-64.
2000: Dewhirst M W; Klitzman B; Braun R D; Brizel D M; Haroon Z A; Secomb T W
Review of methods used to study oxygen transport at the microcirculatory level.
International journal of cancer. Journal international du cancer 2000;90(5):237-55.
2000: Thrall D E; Rosner G L; Azuma C; Larue S M; Case B C; Samulski T; Dewhirst M W
Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2000;16(5):415-28.
2000: Matteucci M L; Anyarambhatla G; Rosner G; Azuma C; Fisher P E; Dewhirst M W; Needham D; Thrall D E
Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3748-55.
2000: Lohr F; Hu K; Haroon Z; Samulski T V; Huang Q; Beaty J; Dewhirst M W; Li C Y
Combination treatment of murine tumors by adenovirus-mediated local B7/IL12 immunotherapy and radiotherapy.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(3):195-203.
2000: Kong G; Braun R D; Dewhirst M W
Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size.
Cancer research 2000;60(16):4440-5.
2000: Meyer R E; Braun R D; Rosner G L; Dewhirst M W
Local 42 degrees C hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside infusion.
Radiation research 2000;154(2):196-201.
2000: Huang Q; Hu J K; Lohr F; Zhang L; Braun R; Lanzen J; Little J B; Dewhirst M W; Li C Y
Heat-induced gene expression as a novel targeted cancer gene therapy strategy.
Cancer research 2000;60(13):3435-9.
2000: Prescott D M; Charles H C; Poulson J M; Page R L; Thrall D E; Vujaskovic Z; Dewhirst M W
The relationship between intracellular and extracellular pH in spontaneous canine tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(6):2501-5.
2000: Anscher M S; Lee C; Hurwitz H; Tyler D; Prosnitz L R; Jowell P; Rosner G; Samulski T; Dewhirst M W
A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer.
International journal of radiation oncology, biology, physics 2000;47(3):719-24.
2000: Needham D; Anyarambhatla G; Kong G; Dewhirst M W
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.
Cancer research 2000;60(5):1197-201.
2000: Blackwell K; Haroon Z; Broadwater G; Berry D; Harris L; Iglehart J D; Dewhirst M; Greenberg C
Plasma D-dimer levels in operable breast cancer patients correlate with clinical stage and axillary lymph node status.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(3):600-8.
2000: Vujaskovic Z; Poulson J M; Gaskin A A; Thrall D E; Page R L; Charles H C; MacFall J R; Brizel D M; Meyer R E; Prescott D M; Samulski T V; Dewhirst M W
Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment.
International journal of radiation oncology, biology, physics 2000;46(1):179-85.
2000: Li C Y; Shan S; Huang Q; Braun R D; Lanzen J; Hu K; Lin P; Dewhirst M W
Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.
Journal of the National Cancer Institute 2000;92(2):143-7.
2000: Haroon Z A; Raleigh J A; Greenberg C S; Dewhirst M W
Early wound healing exhibits cytokine surge without evidence of hypoxia.
Annals of surgery 2000;231(1):137-47.
2000: Li C Y; Shan S; Cao Y; Dewhirst M W
Role of incipient angiogenesis in cancer metastasis.
Cancer metastasis reviews 2000;19(1-2):7-11.
2000: Adams D J; Dewhirst M W; Flowers J L; Gamcsik M P; Colvin O M; Manikumar G; Wani M C; Wall M E
Camptothecin analogues with enhanced antitumor activity at acidic pH.
Cancer chemotherapy and pharmacology 2000;46(4):263-71.
1999: Haroon Z A; Lai T S; Hettasch J M; Lindberg R A; Dewhirst M W; Greenberg C S
Tissue transglutaminase is expressed as a host response to tumor invasion and inhibits tumor growth.
Laboratory investigation; a journal of technical methods and pathology 1999;79(12):1679-86.
1999: Brizel D M; Dodge R K; Clough R W; Dewhirst M W
Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1999;53(2):113-7.
1999: Larue S M; Fox M H; Ogilvie G K; Page R L; Getzy D M; Thrall D E; Johnson J L; Dewhirst M W; Gillette E L
Tumour cell kinetics as predictors of response in canine lymphoma treated with chemotherapy alone or combined with whole body hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(6):475-86.
1999: Prosnitz L R; Maguire P; Anderson J M; Scully S P; Harrelson J M; Jones E L; Dewhirst M; Samulski T V; Powers B E; Rosner G L; Dodge R K; Layfield L; Clough R; Brizel D M
The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy.
International journal of radiation oncology, biology, physics 1999;45(4):941-9.
1999: Haroon Z A; Hettasch J M; Lai T S; Dewhirst M W; Greenberg C S
Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(13):1787-95.
1999: Huang Q; Shan S; Braun R D; Lanzen J; Anyrhambatla G; Kong G; Borelli M; Corry P; Dewhirst M W; Li C Y
Noninvasive visualization of tumors in rodent dorsal skin window chambers.
Nature biotechnology 1999;17(10):1033-5.
1999: Thrall D E; Larue S M; Powers B E; Page R L; Johnson J; George S L; Kornegay J N; McEntee M C; Levesque D C; Smith M; Case B C; Dewhirst M W; Gillette E L
Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(5):383-98.
1999: Kong G; Dewhirst M W
Hyperthermia and liposomes.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1999;15(5):345-70.
1999: Minning D M; Gow A J; Bonaventura J; Braun R; Dewhirst M; Goldberg D E; Stamler J S
Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'.
Nature 1999;401(6752):497-502.
1999: Krol A; Maresca J; Dewhirst M W; Yuan F
Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: implications for drug delivery.
Cancer research 1999;59(16):4136-41.
1999: Braun R D; Lanzen J L; Dewhirst M W
Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats.
The American journal of physiology 1999;277(2 Pt 2):H551-68.
1999: Dunn T J; Braun R D; Rhemus W E; Rosner G L; Secomb T W; Tozer G M; Chaplin D J; Dewhirst M W
The effects of hyperoxic and hypercarbic gases on tumour blood flow.
British journal of cancer 1999;80(1-2):117-26.
1999: Dewhirst M W; Ong E T; Braun R D; Smith B; Klitzman B; Evans S M; Wilson D
Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia.
British journal of cancer 1999;79(11-12):1717-22.
1998: Biaglow J E; Manevich Y; Leeper D; Chance B; Dewhirst M W; Jenkins W T; Tuttle S W; Wroblewski K; Glickson J D; Stevens C; Evans S M
MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.
International journal of radiation oncology, biology, physics 1998;42(4):871-6.
1998: Lanzen J L; Braun R D; Ong A L; Dewhirst M W
Variability in blood flow and pO2 in tumors in response to carbogen breathing.
International journal of radiation oncology, biology, physics 1998;42(4):855-9.
1998: Dewhirst M W; Braun R D; Lanzen J L
Temporal changes in PO2 of R3230AC tumors in Fischer-344 rats.
International journal of radiation oncology, biology, physics 1998;42(4):723-6.
1998: Lin P; Buxton J A; Acheson A; Radziejewski C; Maisonpierre P C; Yancopoulos G D; Channon K M; Hale L P; Dewhirst M W; George S E; Peters K G
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(15):8829-34.
1998: Dewhirst M W
Concepts of oxygen transport at the microcirculatory level.
Seminars in radiation oncology 1998;8(3):143-50.
1998: Dewhirst M W; Corry P M
Further justification for development of non-invasive thermometry.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1998;14(3):255.
1998: Wink D A; Vodovotz Y; Laval J; Laval F; Dewhirst M W; Mitchell J B
The multifaceted roles of nitric oxide in cancer.
Carcinogenesis 1998;19(5):711-21.
1998: Bryce T J; Dewhirst M W; Floyd C E; Hars V; Brizel D M
Artificial neural network model of survival in patients treated with irradiation with and without concurrent chemotherapy for advanced carcinoma of the head and neck.
International journal of radiation oncology, biology, physics 1998;41(2):339-45.
1998: Acker J C; Marks L B; Spencer D P; Yang W; Avery M A; Dodge R K; Rosner G L; Dewhirst M W
Serial in vivo observations of cerebral vasculature after treatment with a large single fraction of radiation.
Radiation research 1998;149(4):350-9.
1998: Sneed P K; Dewhirst M W; Samulski T; Blivin J; Prosnitz L R
Should interstitial thermometry be used for deep hyperthermia?
International journal of radiation oncology, biology, physics 1998;40(5):1015-7.
1998: Lin P; Sankar S; Shan S; Dewhirst M W; Polverini P J; Quinn T Q; Peters K G
Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(1):49-58.
1998: Secomb T W; Hsu R; Braun R D; Ross J R; Gross J F; Dewhirst M W
Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels.
Advances in experimental medicine and biology 1998;454():629-34.
1998: Wilson D F; Evans S M; Jenkins W T; Vinogradov S A; Ong E; Dewhirst M W
Oxygen distributions within R3230Ac tumors growing in dorsal flap window chambers in rats.
Advances in experimental medicine and biology 1998;454():603-9.
1997: Dewhirst M W; Prosnitz L; Thrall D; Prescott D; Clegg S; Charles C; MacFall J; Rosner G; Samulski T; Gillette E; LaRue S
Hyperthermic treatment of malignant diseases: current status and a view toward the future.
Seminars in oncology 1997;24(6):616-25.
1997: Lin P; Polverini P; Dewhirst M; Shan S; Rao P S; Peters K
Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.
The Journal of clinical investigation 1997;100(8):2072-8.
1997: Wong A L; Haroon Z A; Werner S; Dewhirst M W; Greenberg C S; Peters K G
Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.
Circulation research 1997;81(4):567-74.
1997: Nozue M; Lee I; Yuan F; Teicher B A; Brizel D M; Dewhirst M W; Milross C G; Milas L; Song C W; Thomas C D; Guichard M; Evans S M; Koch C J; Lord E M; Jain R K; Suit H D
Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker.
Journal of surgical oncology 1997;66(1):30-8.
1997: Brizel D M; Hage W D; Dodge R K; Munley M T; Piantadosi C A; Dewhirst M W
Hyperbaric oxygen improves tumor radiation response significantly more than carbogen/nicotinamide.
Radiation research 1997;147(6):715-20.
1997: Brizel D M; Sibley G S; Prosnitz L R; Scher R L; Dewhirst M W
Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck.
International journal of radiation oncology, biology, physics 1997;38(2):285-9.
1997: Hauck M L; Coffin D O; Dodge R K; Dewhirst M W; Mitchell J B; Zalutsky M R
A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1997;13(3):307-16.
1997: Anscher M S; Samulski T V; Dodge R; Prosnitz L R; Dewhirst M W
Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate.
International journal of radiation oncology, biology, physics 1997;37(5):1059-65.
1997: Wu N Z; Braun R D; Gaber M H; Lin G M; Ong E T; Shan S; Papahadjopoulos D; Dewhirst M W
Simultaneous measurement of liposome extravasation and content release in tumors.
Microcirculation (New York, N.Y. : 1994) 1997;4(1):83-101.
1997: Braun R D; Dewhirst M W; Hatchell D L
Quantification of erythrocyte flow in the choroid of the albino rat.
The American journal of physiology 1997;272(3 Pt 2):H1444-53.
1997: Hahn J S; Braun R D; Dewhirst M W; Shan S; Snyder S A; Taube J M; Ong E T; Rosner G L; Dodge R K; Bonaventura J; Bonaventura C; DeAngelo J; Meyer R E
Stroma-free human hemoglobin A decreases R3230Ac rat mammary adenocarcinoma blood flow and oxygen partial pressure.
Radiation research 1997;147(2):185-94.
1997: Hauck M L; Dewhirst M W; Bigner D D; Zalutsky M R
Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(1):63-70.
1997: Shan S Q; Rosner G L; Braun R D; Hahn J; Pearce C; Dewhirst M W
Effects of diethylamine/nitric oxide on blood perfusion and oxygenation in the R3230Ac mammary carcinoma.
British journal of cancer 1997;76(4):429-37.
1996: Gaber M H; Wu N Z; Hong K; Huang S K; Dewhirst M W; Papahadjopoulos D
Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks.
International journal of radiation oncology, biology, physics 1996;36(5):1177-87.
1996: Kimura H; Braun R D; Ong E T; Hsu R; Secomb T W; Papahadjopoulos D; Hong K; Dewhirst M W
Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.
Cancer research 1996;56(23):5522-8.
1996: Brizel D M; Scully S P; Harrelson J M; Layfield L J; Dodge R K; Charles H C; Samulski T V; Prosnitz L R; Dewhirst M W
Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas.
Cancer research 1996;56(23):5347-50.
1996: Thrall D E; Samulski T V; Dewhirst M W; Prescott D M
Re: Kapp editorial IJROBP 35:189-194; 1996.
International journal of radiation oncology, biology, physics 1996;36(4):989.
1996: Hettasch J M; Bandarenko N; Burchette J L; Lai T S; Marks J R; Haroon Z A; Peters K; Dewhirst M W; Iglehart J D; Greenberg C S
Tissue transglutaminase expression in human breast cancer.
Laboratory investigation; a journal of technical methods and pathology 1996;75(5):637-45.
1996: Jones D N; McCowage G B; Sostman H D; Brizel D M; Layfield L; Charles H C; Dewhirst M W; Prescott D M; Friedman H S; Harrelson J M; Scully S P; Coleman R E
Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(9):1438-44.
1996: Dewhirst M W; Kimura H; Rehmus S W; Braun R D; Papahadjopoulos D; Hong K; Secomb T W
Microvascular studies on the origins of perfusion-limited hypoxia.
The British journal of cancer. Supplement 1996;27():S247-51.
1996: Dewhirst M W; Ong E T; Rosner G L; Rehmus S W; Shan S; Braun R D; Brizel D M; Secomb T W
Arteriolar oxygenation in tumour and subcutaneous arterioles: effects of inspired air oxygen content.
The British journal of cancer. Supplement 1996;27():S241-6.
1996: Lindberg R A; Dewhirst M W; Buckley B J; Hughes C S; Whorton A R
Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.
The American journal of physiology 1996;271(1 Pt 1):C332-7.
1996: Hauck M L; Price G S; Ogilvie G K; Johnson J; Gillette E L; Thrall D E; Dewhirst M W; Page R L
Phase I evaluation of mitoxantrone alone and combined with whole body hyperthermia in dogs with lymphoma.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996;12(3):309-20.
1996: Hauck M L; Dewhirst M W; Zalutsky M R
The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody.
Nuclear medicine and biology 1996;23(4):551-7.
1996: Rosner G L; Clegg S T; Prescott D M; Dewhirst M W
Estimation of cell survival in tumours heated to nonuniform temperature distributions.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996;12(2):303-4.
1996: Rosner G L; Clegg S T; Prescott D M; Dewhirst M W
Estimation of cell survival in tumours heated to nonuniform temperature distributions.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1996;12(2):223-39.
1996: Gulledge C J; Dewhirst M W
Tumor oxygenation: a matter of supply and demand.
Anticancer research 1996;16(2):741-9.
1996: Brizel D M; Scully S P; Harrelson J M; Layfield L J; Bean J M; Prosnitz L R; Dewhirst M W
Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma.
Cancer research 1996;56(5):941-3.
1996: Thrall D E; Prescott D M; Samulski T V; Rosner G L; Denman D L; Legorreta R L; Dodge R K; Page R L; Cline J M; Lee J; Case B C; Evans S M; Oleson J R; Dewhirst M W
Radiation plus local hyperthermia versus radiation plus the combination of local and whole-body hyperthermia in canine sarcomas.
International journal of radiation oncology, biology, physics 1996;34(5):1087-96.
1996: Zalutsky M R; Schuster J M; Garg P K; Archer G E; Dewhirst M W; Bigner D D
Two approaches for enhancing radioimmunotherapy: alpha emitters and hyperthermia.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1996;141():101-22.
1995: Prosnitz L R; Dewhirst M W
Progress toward a thermal dosimetry system.
International journal of radiation oncology, biology, physics 1995;33(4):963-4.
1995: Brizel D M; Lin S; Johnson J L; Brooks J; Dewhirst M W; Piantadosi C A
The mechanisms by which hyperbaric oxygen and carbogen improve tumour oxygenation.
British journal of cancer 1995;72(5):1120-4.
1995: Kimura H; Wu N Z; Dodge R; Spencer D P; Klitzman B M; McIntyre T M; Dewhirst M W
Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021.
International journal of radiation oncology, biology, physics 1995;33(3):627-33.
1995: Dewhirst M W; LaRue S M; Gerweck L
Tumor physiology and cell kinetics.
Seminars in veterinary medicine and surgery (small animal) 1995;10(3):148-57.
1995: Brizel D M; Rosner G L; Prosnitz L R; Dewhirst M W
Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases.
International journal of radiation oncology, biology, physics 1995;32(4):1121-5.
1995: Page R L; Lee J; Riviere J E; Dodge R K; Thrall D E; Dewhirst M W
Absence of whole body hyperthermia effect on cisplatin distribution in spontaneous canine tumors.
International journal of radiation oncology, biology, physics 1995;32(4):1097-102.
1995: Castellino S M; Friedman H S; Elion G B; Ong E T; Marcelli S L; Page R; Bigner D D; Dewhirst M W
Flunarizine enhancement of melphalan activity against drug-sensitive/resistant rhabdomyosarcoma.
British journal of cancer 1995;71(6):1181-7.
1995: Meyer R E; Shan S; DeAngelo J; Dodge R K; Bonaventura J; Ong E T; Dewhirst M W
Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.
British journal of cancer 1995;71(6):1169-74.
1995: Foltz R M; McLendon R E; Friedman H S; Dodge R K; Bigner D D; Dewhirst M W
A pial window model for the intracranial study of human glioma microvascular function.
Neurosurgery 1995;36(5):976-84; discussion 984-5.
1995: Schuster J M; Zalutsky M R; Noska M A; Dodge R; Friedman H S; Bigner D D; Dewhirst M W
Hyperthermic modulation of radiolabelled antibody uptake in a human glioma xenograft and normal tissues.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1995;11(1):59-72.
1995: Secomb T W; Hsu R; Ong E T; Gross J F; Dewhirst M W
Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors.
Acta oncologica (Stockholm, Sweden) 1995;34(3):313-6.
1994: Brizel D M; Dodge R; Dewhirst M W
The effect of the perflubron emulsion Oxygent on the calibration characteristics of polarographic oxygen electrodes.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 1994;33(3):262-5.
1994: Page R L; McEntee M C; Williams P L; George S L; Price G S; Novotney C A; Hauck M L; Riviere J E; Dewhirst M W; Thrall D E
Effect of whole body hyperthermia on carboplatin disposition and toxicity in dogs.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1994;10(6):807-16.
1994: Brizel D M; Rosner G L; Harrelson J; Prosnitz L R; Dewhirst M W
Pretreatment oxygenation profiles of human soft tissue sarcomas.
International journal of radiation oncology, biology, physics 1994;30(3):635-42.
1994: Dewhirst M W; Secomb T W; Ong E T; Hsu R; Gross J F
Determination of local oxygen consumption rates in tumors.
Cancer research 1994;54(13):3333-6.
1994: Wu N Z; Ross B A; Gulledge C; Klitzman B; Dodge R; Dewhirst M W
Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation.
British journal of cancer 1994;69(5):883-9.
1994: Dewhirst M W
Future directions in hyperthermia biology.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1994;10(3):339-45.
1994: Clegg S T; Samulski T V; Murphy K A; Rosner G L; Dewhirst M W
Inverse techniques in hyperthermia: a sensitivity study.
IEEE transactions on bio-medical engineering 1994;41(4):373-82.
1994: Krishna M C; Dewhirst M W; Friedman H S; Cook J A; DeGraff W; Samuni A; Russo A; Mitchell J B
Hyperthermic sensitization by the radical initiator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). I. In vitro studies.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1994;10(2):271-81.
1994: Sostman H D; Prescott D M; Dewhirst M W; Dodge R K; Thrall D E; Page R L; Tucker J A; Harrelson J M; Reece G; Leopold K A
MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas.
Radiology 1994;190(1):269-75.
1993: Leopold K A; Oleson J R; Clarke-Pearson D; Soper J; Berchuck A; Samulski T V; Page R L; Blivin J; Tomberlin J K; Dewhirst M W
Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma.
International journal of radiation oncology, biology, physics 1993;27(5):1245-51.
1993: Wu N Z; Klitzman B; Rosner G; Needham D; Dewhirst M W
Measurement of material extravasation in microvascular networks using fluorescence video-microscopy.
Microvascular research 1993;46(2):231-53.
1993: Prescott D M; Charles H C; Sostman H D; Page R L; Thrall D E; Moore D; Oleson J R; Dewhirst M W
Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1993;9(5):745-54.
1993: Wu N Z; Da D; Rudoll T L; Needham D; Whorton A R; Dewhirst M W
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue.
Cancer research 1993;53(16):3765-70.
1993: Page R L; McEntee M C; George S L; Williams P L; Heidner G L; Novotney C A; Riviere J E; Dewhirst M W; Thrall D E
Pharmacokinetic and phase I evaluation of carboplatin in dogs.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1993;7(4):235-40.
1993: Dewhirst M W; Griffin T W; Smith A R; Parker R G; Hanks G E; Brady L W
Intersociety Council on Radiation Oncology essay on the introduction of new medical treatments into practice.
Journal of the National Cancer Institute 1993;85(12):951-7.
1993: Teicher B A; Holden S A; Northey D; Dewhirst M W; Herman T S
Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside.
International journal of radiation oncology, biology, physics 1993;26(1):103-9.
1993: Leopold K A; Dewhirst M W; Samulski T V; Dodge R K; George S L; Blivin J L; Prosnitz L R; Oleson J R
Cumulative minutes with T90 greater than Tempindex is predictive of response of superficial malignancies to hyperthermia and radiation.
International journal of radiation oncology, biology, physics 1993;25(5):841-7.
1993: Kavanagh B D; Coffey B E; Needham D; Hochmuth R M; Dewhirst M W
The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment.
British journal of cancer 1993;67(4):734-41.
1993: Dewhirst M W
Factors influencing hyperthermic enhancement of drug cytotoxicity.
International journal of radiation oncology, biology, physics 1993;25(3):569-70.
1993: Secomb T W; Hsu R; Dewhirst M W; Klitzman B; Gross J F
Analysis of oxygen transport to tumor tissue by microvascular networks.
International journal of radiation oncology, biology, physics 1993;25(3):481-9.
1993: Oleson J R; Samulski T V; Leopold K A; Clegg S T; Dewhirst M W; Dodge R K; George S L
Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment.
International journal of radiation oncology, biology, physics 1993;25(2):289-97.
1993: Brizel D M; Klitzman B; Cook J M; Edwards J; Rosner G; Dewhirst M W
A comparison of tumor and normal tissue microvascular hematocrits and red cell fluxes in a rat window chamber model.
International journal of radiation oncology, biology, physics 1993;25(2):269-76.
1993: Castellino S; Elion G B; Griffith O W; Dewhirst M; Kurtzberg J; Cattley R C; Scott P; Bigner D D; Friedman H S
Development of a model of melphalan-induced gastrointestinal toxicity in mice.
Cancer chemotherapy and pharmacology 1993;31(5):376-80.
1992: Page R L; Thrall D E; George S L; Price G S; Heidner G L; McEntee M C; Novotney C A; Hauck M L; Dewhirst M W
Quantitative estimation of the thermal dose-modifying factor for cis-diamminedichloroplatinum (CDDP) in tumour-bearing dogs.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(6):761-9.
1992: Dewhirst M W; Ong E T; Madwed D; Klitzman B; Secomb T; Brizel D; Bonaventura J; Rosner G; Kavanagh B; Edwards J
Effects of the calcium channel blocker flunarizine on the hemodynamics and oxygenation of tumor microvasculature.
Radiation research 1992;132(1):61-8.
1992: Wu N Z; Klitzman B; Dodge R; Dewhirst M W
Diminished leukocyte-endothelium interaction in tumor microvessels.
Cancer research 1992;52(15):4265-8.
1992: Novotney C A; Page R L; Macy D W; Dewhirst M W; Ogilvie G K; Withrow S J; McEntee M C; Heidner G L; Allen S A; Thrall D E
Phase I evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1992;6(4):245-9.
1992: Dewhirst M W; Vinuya R Z; Ong E T; Klitzman B; Rosner G; Secomb T W; Gross J F
Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature.
Radiation research 1992;130(3):345-54.
1992: Gillette S M; Dewhirst M W; Gillette E L; Thrall D E; Page R L; Powers B E; Withrow S J; Rosner G; Wong C; Sim D A
Response of canine soft tissue sarcomas to radiation or radiation plus hyperthermia: a randomized phase II study.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(3):309-20.
1992: Dewhirst M W; Ong E T; Klitzman B; Secomb T W; Vinuya R Z; Dodge R; Brizel D; Gross J F
Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber.
Radiation research 1992;130(2):171-82.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Casero R A; Scott P A; Bullock N; Bigner D D; Friedman H S
Effects of glutathione or polyamine depletion on in vivo thermosensitization.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(2):199-208.
1992: Page R L; Macy D W; Ogilvie G K; Rosner G L; Dewhirst M W; Thrall D E; Withrow S J; McEntee M C; Cline J M; Heidner G L
Phase III evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(2):187-97.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Savina P M; Blum M R; Prescott D M; Bigner D D; Friedman H S
Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft.
Radiation research 1992;129(2):218-23.
1992: Thrall D E; Prescott D M; Samulski T V; Dewhirst M W; Cline J M; Lee J; Page R L; Oleson J R
Serious toxicity associated with annular microwave array induction of whole-body hyperthermia in normal dogs.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(1):23-32.
1992: Laskowitz D T; Elion G B; Dewhirst M W; Griffith O W; Cattley R C; Bigner D D; Friedman H S
Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1992;8(1):111-20.
1992: Rine G P; Dewhirst M W; Cobb E D; Clegg S T; Coleman E N; Samulski T V; Wallen C A
Feasibility of estimating the temperature distribution in a tumor heated by a waveguide applicator.
International journal of radiation oncology, biology, physics 1992;23(5):1009-19.
1992: Prescott D M; Samulski T V; Dewhirst M W; Page R L; Thrall D E; Dodge R K; Oleson J R
Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs.
International journal of radiation oncology, biology, physics 1992;23(2):377-85.
1992: Leopold K A; Dewhirst M; Samulski T; Harrelson J; Tucker J A; George S L; Dodge R K; Grant W; Clegg S; Prosnitz L R
Relationships among tumor temperature, treatment time, and histopathological outcome using preoperative hyperthermia with radiation in soft tissue sarcomas.
International journal of radiation oncology, biology, physics 1992;22(5):989-98.
1991: Marks L B; Dewhirst M
Accelerated repopulation: friend or foe? Exploiting changes in tumor growth characteristics to improve the "efficiency" of radiotherapy.
International journal of radiation oncology, biology, physics 1991;21(5):1377-83.
1991: Lilley E R; Elion G B; Dewhirst M W; Schold S C; Blum M R; Savina P M; Laskowitz D T; Bigner D D; Friedman H S
Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR.
Cancer research 1991;51(15):3906-9.
1991: Page R L; Thrall D E; Dewhirst M W; Macy D W; George S L; McEntee M C; Heidner G L; Novotney C A; Allen S A; Withrow S J
Phase I study of melphalan alone and melphalan plus whole body hyperthermia in dogs with malignant melanoma.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1991;7(4):559-66.
1991: Emami B; Stauffer P; Dewhirst M W; Prionas S; Ryan T; Corry P; Herman T; Kapp D S; Myerson R J; Samulski T
RTOG quality assurance guidelines for interstitial hyperthermia.
International journal of radiation oncology, biology, physics 1991;20(5):1117-24.
1991: Sapozink M D; Corry P M; Kapp D S; Myerson R J; Dewhirst M W; Emami B; Herman T; Prionas S; Ryan T; Samulski T
RTOG quality assurance guidelines for clinical trials using hyperthermia for deep-seated malignancy.
International journal of radiation oncology, biology, physics 1991;20(5):1109-15.
1991: Waterman F M; Dewhirst M W; Fessenden P; Samulski T V; Stauffer P; Emami B; Corry P; Prionas S D; Sapozink M; Herman T
RTOG quality assurance guidelines for clinical trials using hyperthermia administered by ultrasound.
International journal of radiation oncology, biology, physics 1991;20(5):1099-107.
1990: Dewhirst M W; Prescott D M; Clegg S; Samulski T V; Page R L; Thrall D E; Leopold K; Rosner G; Acker J C; Oleson J R
The use of hydralazine to manipulate tumour temperatures during hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1990;6(6):971-83.
1990: Sostman H D; Charles H C; Rockwell S; Leopold K; Beam C; Madwed D; Dewhirst M; Cofer G; Moore D; Burn R
Soft-tissue sarcomas: detection of metabolic heterogeneity with P-31 MR spectroscopy.
Radiology 1990;176(3):837-43.
1990: Samulski T V; Grant W J; Oleson J R; Leopold K A; Dewhirst M W; Vallario P; Blivin J
Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1990;6(5):909-22.
1990: Dewhirst M W; Phillips T L; Samulski T V; Stauffer P; Shrivastava P; Paliwal B; Pajak T; Gillim M; Sapozink M; Myerson R
RTOG quality assurance guidelines for clinical trials using hyperthermia.
International journal of radiation oncology, biology, physics 1990;18(5):1249-59.
1990: Riviere J E; Page R L; Rogers R A; Chang S K; Dewhirst M W; Thrall D E
Nonuniform alteration of cis-diamminedichloroplatinum(II) tissue distribution in dogs with whole body hyperthermia.
Cancer research 1990;50(7):2075-80.
1990: Cope D A; Dewhirst M W; Friedman H S; Bigner D D; Zalutsky M R
Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.
Cancer research 1990;50(6):1803-9.
1990: Thrall D E; Dewhirst M W; Page R L; Samulski T V; McLeod D A; Oleson J R
A comparison of temperatures in canine solid tumours during local and whole-body hyperthermia administered alone and simultaneously.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1990;6(2):305-17.
1990: Acker J C; Dewhirst M W; Honoré G M; Samulski T V; Tucker J A; Oleson J R
Blood perfusion measurements in human tumours: evaluation of laser Doppler methods.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1990;6(2):287-304.
1990: Dewhirst M W; Oliver R; Tso C Y; Gustafson C; Secomb T; Gross J F
Heterogeneity in tumor microvascular response to radiation.
International journal of radiation oncology, biology, physics 1990;18(3):559-68.
1990: Dewhirst M W; Sostman H D; Leopold K A; Charles H C; Moore D; Burn R A; Tucker J A; Harrelson J M; Oleson J R
Soft-tissue sarcomas: MR imaging and MR spectroscopy for prognosis and therapy monitoring. Work in progress.
Radiology 1990;174(3 Pt 1):847-53.
1989: Edelstein-Keshet L; Dewhirst M W; Oleson J R; Samulski T V
Characterization of tumour temperature distributions in hyperthermia based on assumed mathematical forms.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1989;5(6):757-77.
1989: Dewhirst M W; Tso C Y; Oliver R; Gustafson C S; Secomb T W; Gross J F
Morphologic and hemodynamic comparison of tumor and healing normal tissue microvasculature.
International journal of radiation oncology, biology, physics 1989;17(1):91-9.
1989: Dewhirst M W
Animal modeling and thermal dose.
Radiologic clinics of North America 1989;27(3):509-18.
1989: Thrall D E; Page R L; Dewhirst M W; Macy D W; McLeod D A; Scott R J; Allen S; Gillette E L
Whole body hyperthermia in dogs using a radiant heating device: effect of surface cooling on temperature uniformity.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1989;5(2):137-43.
1989: Oleson J R; Dewhirst M W; Harrelson J M; Leopold K A; Samulski T V; Tso C Y
Tumor temperature distributions predict hyperthermia effect.
International journal of radiation oncology, biology, physics 1989;16(3):559-70.
1989: Engler M J; Dewhirst M W; Oleson J R
Stability of temperatures during hyperthermia treatments.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1989;5(1):59-67.
1989: McChesney S L; Withrow S J; Gillette E L; Powers B E; Dewhirst M W
Radiotherapy of soft tissue sarcomas in dogs.
Journal of the American Veterinary Medical Association 1989;194(1):60-3.
1989: Leopold K A; Harrelson J; Prosnitz L; Samulski T V; Dewhirst M W; Oleson J R
Preoperative hyperthermia and radiation for soft tissue sarcomas: advantage of two vs one hyperthermia treatments per week.
International journal of radiation oncology, biology, physics 1989;16(1):107-15.
1988: Oleson J R; Calderwood S K; Coughlin C T; Dewhirst M W; Gerweck L E; Gibbs F A; Kapp D S
Biological and clinical aspects of hyperthermia in cancer therapy.
American journal of clinical oncology 1988;11(3):368-80.
1988: Page R L; Macy D W; Thrall D E; Dewhirst M W; Allen S L; Heidner G L; Sim D A; McGee M L; Gillette E L
Unexpected toxicity associated with use of body surface area for dosing melphalan in the dog.
Cancer research 1988;48(2):288-90.
1987: Gillette E L; McChesney S L; Dewhirst M W; Scott R J
Response of canine oral carcinomas to heat and radiation.
International journal of radiation oncology, biology, physics 1987;13(12):1861-7.
1987: Dewhirst M W; Gustafson C; Gross J F; Tso C Y
Temporal effects of 5.0 Gy radiation in healing subcutaneous microvasculature of a dorsal flap window chamber.
Radiation research 1987;112(3):581-91.
1987: Page R L; Meyer R E; Thrall D E; Dewhirst M W
Cardiovascular and metabolic response of tumour-bearing dogs to whole body hyperthermia.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1987;3(6):513-25.
1987: Zakris E L; Dewhirst M W; Riviere J E; Hoopes P J; Page R L; Oleson J R
Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(10):1613-20.
1987: Engler M J; Dewhirst M W; Winget J M; Oleson J R
Automated temperature scanning for hyperthermia treatment monitoring.
International journal of radiation oncology, biology, physics 1987;13(9):1377-82.
1987: Dewhirst M W; Winget J M; Edelstein-Keshet L; Sylvester J; Engler M; Thrall D E; Page R L; Oleson J R
Clinical application of thermal isoeffect dose.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1987;3(4):307-18.
1987: Page R L; Thrall D E; Dewhirst M W; Meyer R E
Whole-body hyperthermia. Rationale and potential use for cancer treatment.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1987;1(3):110-20.
1987: Klein M K; Dewhirst M W; Fuller D J
Whole body hyperthermia and heat-sensitizing drugs: a pilot study in canine lymphoproliferative disease.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1987;3(3):187-98.
1986: Thrall D E; Page R L; Dewhirst M W; Meyer R E; Hoopes P J; Kornegay J N
Temperature measurements in normal and tumor tissue of dogs undergoing whole body hyperthermia.
Cancer research 1986;46(12 Pt 1):6229-35.
1986: Meyer R E; Page R L; Thrall D E; Dewhirst M W; Vose D L
Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia.
Cancer research 1986;46(11):5599-601.
1986: McChesney S L; Gillette E L; Dewhirst M W; Withrow S J
Influence of WR 2721 on radiation response of canine soft tissue sarcomas.
International journal of radiation oncology, biology, physics 1986;12(11):1957-63.
1986: Riviere J E; Page R L; Dewhirst M W; Tyczkowska K; Thrall D E
Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1986;2(4):351-8.
1986: Dewhirst M W; Sim D A
Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1986;2(2):165-78.
1985: Thrall D E; Dewhirst M W
Use of radiation and/or hyperthermia for treatment of mast cell tumors and lymphosarcoma in dogs.
The Veterinary clinics of North America. Small animal practice 1985;15(4):835-43.
1985: Dewhirst M W; Sim D A; Forsyth K; Grochowski K J; Wilson S; Bicknell E
Local control and distant metastases in primary canine malignant melanomas treated with hyperthermia and/or radiotherapy.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1985;1(3):219-34.
1984: Dewhirst M W; Sim D A
The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia.
Cancer research 1984;44(10 Suppl):4772s-4780s.
1984: Oleson J R; Assaad A; Dewhirst M W; DeYoung D W; Grochowski K J; Sim D A
Regional hyperthermia by magnetic induction in a beagle dog model: analysis of thermal dosimetry.
Radiation research 1984;98(3):445-55.
1984: Stauffer P R; Cetas T C; Fletcher A M; DeYoung D W; Dewhirst M W; Oleson J R; Roemer R B
Observations on the use of ferromagnetic implants for inducing hyperthermia.
IEEE transactions on bio-medical engineering 1984;31(1):76-90.
1984: Dewhirst M W; Sim D A; Sapareto S; Connor W G
Importance of minimum tumor temperature in determining early and long-term responses of spontaneous canine and feline tumors to heat and radiation.
Cancer research 1984;44(1):43-50.
1984: Dewhirst M W; Sim D A
Analysis of prognostic variables which influence early and long-term response of pet animal tumors to radiation alone and radiation plus heat.
Frontiers of radiation therapy and oncology 1984;18():47-55.
1983: Dewhirst M W; Sim D A; Wilson S; DeYoung D; Parsells J L
Correlation between initial and long-term responses of spontaneous pet animal tumors to heat and radiation or radiation alone.
Cancer research 1983;43(12 Pt 1):5735-41.
1983: Oleson J R; Dewhirst M W
Hyperthermia: an overview of current progress and problems.
Current problems in cancer 1983;8(6):1-62.
1982: Dewhirst M W; Connor W G; Sim D A
Preliminary results of a phase III trial of spontaneous animal tumors to heat and/or radiation: early normal tissue response and tumor volume influence on initial response.
International journal of radiation oncology, biology, physics 1982;8(11):1951-61.
1980: Dewhirst M W; Ozimek E J; Gross J; Cetas T C
Will hyperthermia conquer the elusive hypoxic cell? Implications of heat effects on tumor and normal-tissue microcirculation.
Radiology 1980;137(3):811-7.
1978: Phillips R K; Dewhirst M W; Gillette E L; Clow D J
Electrophoretic evaluation of sera from dogs with cancer.
American journal of veterinary research 1978;39(9):1482-6.
1977: Dewhirst M W; Stamp G L; Hurvitz A I
Idiopathic monoclonal (IgA) gammopathy in a dog.
Journal of the American Veterinary Medical Association 1977;170(11):1313-6.

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