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roberto weinmann

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Mhairi Copland; Francesca Pellicano; Linda Richmond; Elaine K Allan; Ashley Hamilton; Francis Y Lee; roberto weinmann; Tessa L Holyoake
BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors.
Yiguo Hu; Sarah Swerdlow; Theodore M Duffy; roberto weinmann; Francis Y Lee; Shaoguang Li
Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.
Thomas E Spires; Brian E Fink; Ellen K Kick; Dan You; Cheryl A Rizzo; Ivone Takenaka; R Michael Lawrence; Zheming Ruan; Mark E Salvati; Gregory D Vite; roberto weinmann; Ricardo M Attar; Marco Gottardis; Matthew V Lorenzi
Identification of novel functional inhibitors of 17beta-hydroxysteroid dehydrogenase type III (17beta-HSD3).

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All Publications

2008: Mhairi Copland; Francesca Pellicano; Linda Richmond; Elaine K Allan; Ashley Hamilton; Francis Y Lee; roberto weinmann; Tessa L Holyoake
BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors.
Blood 2008;111(5):2843-53.
2006: Yiguo Hu; Sarah Swerdlow; Theodore M Duffy; roberto weinmann; Francis Y Lee; Shaoguang Li
Targeting multiple kinase pathways in leukemic progenitors and stem cells is essential for improved treatment of Ph+ leukemia in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(45):16870-5.
2005: Thomas E Spires; Brian E Fink; Ellen K Kick; Dan You; Cheryl A Rizzo; Ivone Takenaka; R Michael Lawrence; Zheming Ruan; Mark E Salvati; Gregory D Vite; roberto weinmann; Ricardo M Attar; Marco Gottardis; Matthew V Lorenzi
Identification of novel functional inhibitors of 17beta-hydroxysteroid dehydrogenase type III (17beta-HSD3).
The Prostate 2005;65(2):159-70.
2005: Mark E Salvati; Aaron Balog; Donna D Wei; Dacia Pickering; Ricardo M Attar; Jieping Geng; Cheryl A Rizzo; John T Hunt; Marco Gottardis; roberto weinmann; Rogelio Martinez
Identification of a novel class of androgen receptor antagonists based on the bicyclic-1H-isoindole-1,3(2H)-dione nucleus.
Bioorganic & medicinal chemistry letters 2005;15(2):389-93.
2005: Mark E Salvati; Aaron Balog; Weifang Shan; Donna D Wei; Dacia Pickering; Ricardo M Attar; Jieping Geng; Cheryl A Rizzo; Marco Gottardis; roberto weinmann; Stanley R Krystek; John S Sack; Yongmi An; Kevin Kish
Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists.
Bioorganic & medicinal chemistry letters 2005;15(2):271-6.
2004: Aaron Balog; Mark E Salvati; Weifang Shan; Arvind Mathur; Leslie Leith; Donna D Wei; Ricardo M Attar; Jieping Geng; Cheryl A Rizzo; Chihuei Wang; Stanley R Krystek; John S Tokarski; John T Hunt; Marco Gottardis; roberto weinmann
The synthesis and evaluation of [2.2.1]-bicycloazahydantoins as androgen receptor antagonists.
Bioorganic & medicinal chemistry letters 2004;14(24):6107-11.
2001: John S Sack; Kevin Kish; Chihuei Wang; Ricardo M Attar; Susan E Kiefer; Yongmi An; G Y Wu; Julie E Scheffler; Mark E Salvati; Stanley R Krystek; roberto weinmann; H M Einspahr
Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):4904-9.
1997: N Sang; P P Claudio; Y Fu; Nobuo Horikoshi; U Graeven; roberto weinmann; Antonio Giordano
Transforming region of 243R E1A contains two overlapping but distinct transactivation domains.
DNA and cell biology 1997;16(11):1321-33.
1996: Fatah Kashanchi; Samir N Khleif; J F Duvall; M Reza Sadaie; Michael F Radonovich; M Cho; Malcolm Martin; S Y Chen; roberto weinmann; John N Brady
Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.
Journal of virology 1996;70(8):5503-10.
1995: J M Carboni; N Yan; Adrienne D Cox; X Bustelo; S M Graham; M J Lynch; roberto weinmann; B R Seizinger; Channing J Der; Mariano Barbacid
Farnesyltransferase inhibitors are inhibitors of Ras but not R-Ras2/TC21, transformation.
Oncogene 1995;10(10):1905-13.
1995: B A Lewis; G Tullis; E Seto; Nobuo Horikoshi; roberto weinmann; Thomas Shenk
Adenovirus E1A proteins interact with the cellular YY1 transcription factor.
Journal of virology 1995;69(3):1628-36.
1995: Nobuo Horikoshi; A Usheva; Jiandong Chen; Arnold J Levine; roberto weinmann; Thomas Shenk
Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression.
Molecular and cellular biology 1995;15(1):227-34.
1994: K Rideg; G Hirka; K Prakash; L M Bushar; J Y Nothias; roberto weinmann; Peter W Andrews; Eva Gönczöl
DNA-binding proteins that interact with the 19-base pair (CRE-like) element from the HCMV major immediate early promoter in differentiating human embryonal carcinoma cells.
Differentiation; research in biological diversity 1994;56(1-2):119-29.
1993: I Beck; roberto weinmann; Jaime Caro
Characterization of hypoxia-responsive enhancer in the human erythropoietin gene shows presence of hypoxia-inducible 120-Kd nuclear DNA-binding protein in erythropoietin-producing and nonproducing cells.
Blood 1993;82(3):704-11.
1993: J Y Nothias; roberto weinmann; D Blangy; F Melin
Analysis of transcription factors binding to the duplicated PEA1 and PEA3 sites that are required for polyomavirus mutant expression in PCC4 embryonic carcinoma cells.
Journal of virology 1993;67(6):3036-47.
1992: E Seto; A Usheva; G P Zambetti; Jamil Momand; Nobuo Horikoshi; roberto weinmann; Arnold J Levine; Thomas Shenk
Wild-type p53 binds to the TATA-binding protein and represses transcription.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):12028-32.
1992: A Kralli; R Ge; Ullrich Graeven; Robert P Ricciardi; roberto weinmann
Negative regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells via a retinoic acid response element.
Journal of virology 1992;66(12):6979-88.
1992: R Ge; A Kralli; roberto weinmann; Robert P Ricciardi
Down-regulation of the major histocompatibility complex class I enhancer in adenovirus type 12-transformed cells is accompanied by an increase in factor binding.
Journal of virology 1992;66(12):6969-78.
1992: Bruce Lamb; Kapaettu Satyamoorthy; D Solter; A Basu; M Q Xu; roberto weinmann; CC Howe
A DNA element that regulates expression of an endogenous retrovirus during F9 cell differentiation is E1A dependent.
Molecular and cellular biology 1992;12(11):4824-33.
1992: Ullrich Graeven; Ulrich Rodeck; roberto weinmann; Meenhard Herlyn
Stable transfection of human malignant melanoma cells with basic fibroblast growth factor antisense cDNA.
Annals of the New York Academy of Sciences 1992;660():293-4.
1992: roberto weinmann
The basic RNA polymerase II transcriptional machinery.
Gene expression 1992;2(2):81-91.
1991: H Lu; O Flores; roberto weinmann; Danny Reinberg
The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(22):10004-8.
1991: I Beck; S Ramirez; roberto weinmann; Jaime Caro
Enhancer element at the 3'-flanking region controls transcriptional response to hypoxia in the human erythropoietin gene.
The Journal of biological chemistry 1991;266(24):15563-6.
1991: K Maguire; X P Shi; Nobuo Horikoshi; J Rappaport; M Rosenberg; roberto weinmann
Interactions between adenovirus E1A and members of the AP-1 family of cellular transcription factors.
Oncogene 1991;6(8):1417-22.
1991: Nobuo Horikoshi; K Maguire; A Kralli; E Maldonado; D Reinberg; roberto weinmann
Direct interaction between adenovirus E1A protein and the TATA box binding transcription factor IID.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5124-8.
1991: Srilata Bagchi; roberto weinmann; Pradip Raychaudhuri
The retinoblastoma protein copurifies with E2F-I, an E1A-regulated inhibitor of the transcription factor E2F.
Cell 1991;65(6):1063-72.
1991: Robert Clark; K W Cho; roberto weinmann; B A Hamkalo
Preferential distribution of active RNA polymerase II molecules in the nuclear periphery.
Gene expression 1991;1(1):61-70.
1990: P Costa-Giomi; Jaime Caro; roberto weinmann
Enhancement by hypoxia of human erythropoietin gene transcription in vitro.
The Journal of biological chemistry 1990;265(18):10185-8.
1990: J Caceres; G Glikin; R Bravo; roberto weinmann
c-fos mediated stimulation of an AP-1 DNA binding activity in undifferentiated teratocarcinoma cell lines.
Oncogene 1990;5(1):59-67.
1989: D Lazard; C Fernández-Tomás; Patricio Gariglio; roberto weinmann
Modification of an adenovirus major late promoter-binding factor during poliovirus infection.
Journal of virology 1989;63(9):3858-64.
1989: J Carcamo; S Lobos; A Merino; L Buckbinder; roberto weinmann; V Natarajan; Danny Reinberg
Factors involved in specific transcription by mammalian RNA polymerase II. Role of factors IID and MLTF in transcription from the adenovirus major late and IVa2 promoters.
The Journal of biological chemistry 1989;264(13):7704-14.
1989: A G Saltzman; roberto weinmann
Promoter specificity and modulation of RNA polymerase II transcription.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(6):1723-33.
1989: SJ Schuster; Evangelos Badiavas; P Costa-Giomi; roberto weinmann; A J Erslev; Jaime Caro
Stimulation of erythropoietin gene transcription during hypoxia and cobalt exposure.
Blood 1989;73(1):13-6.
1988: C J Goldenberg; Y Luo; M Fenna; Ruben Baler; roberto weinmann; Richard Voellmy
Purified human factor activates heat shock promoter in a HeLa cell-free transcription system.
The Journal of biological chemistry 1988;263(36):19734-9.
1988: R Zandomeni; M C Zandomeni; roberto weinmann
A rapid purification method for calf thymus casein kinase II.
FEBS letters 1988;235(1-2):247-51.
1988: J Rappaport; K Cho; A Saltzman; J Prenger; M Golomb; roberto weinmann
Transcription elongation factor SII interacts with a domain of the large subunit of human RNA polymerase II.
Molecular and cellular biology 1988;8(8):3136-42.
1988: R F Lee; M F Concino; roberto weinmann
Genetic profile of the transcriptional signals from the adenovirus major late promoter.
Virology 1988;165(1):51-6.
1988: O J Nielsen; P Costa-Giomi; roberto weinmann; A J Erslev; Jaime Caro
Erythropoietin-beta-D-galactosidase. The generation, purification and use of a fusion protein.
Journal of immunological methods 1988;111(1):1-9.
1987: J Rappaport; roberto weinmann
Purine triphosphate beta-gamma bond hydrolysis requirements for RNA polymerase II transcription initiation and elongation.
The Journal of biological chemistry 1987;262(36):17510-5.
1987: A Taylor; Catherine C Allende; roberto weinmann; Jorge E Allende
The phosphorylation of nucleoplasmin by casein kinase-2 is resistant to heparin inhibition.
FEBS letters 1987;226(1):109-14.
1987: Maria Cristina Cuturi; M Murphy; M P Costa-Giomi; roberto weinmann; B Perussia; G Trinchieri
Independent regulation of tumor necrosis factor and lymphotoxin production by human peripheral blood lymphocytes.
The Journal of experimental medicine 1987;165(6):1581-94.
1987: J Rappaport; D Reinberg; R Zandomeni; roberto weinmann
Purification and functional characterization of transcription factor SII from calf thymus. Role in RNA polymerase II elongation.
The Journal of biological chemistry 1987;262(11):5227-32.
1986: Linda Cannizzaro; B S Emanuel; K W Cho; roberto weinmann
The gene encoding the large subunit of human RNA polymerase II is located on the short arm of chromosome 17.
American journal of human genetics 1986;38(6):812-8.
1986: X P Shi; R Lee; roberto weinmann
Protein factor(s) binding independently to two different regions of the adenovirus 2 major late promoter.
Nucleic acids research 1986;14(9):3729-44.
1986: J L Sagripanti; R O Zandomeni; roberto weinmann
The cap structure of simian hemorrhagic fever virion RNA.
Virology 1986;151(1):146-50.
1986: R Zandomeni; M C Zandomeni; D Shugar; roberto weinmann
Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.
The Journal of biological chemistry 1986;261(7):3414-9.
1985: K W Cho; Kamel Khalili; R Zandomeni; roberto weinmann
The gene encoding the large subunit of human RNA polymerase II.
The Journal of biological chemistry 1985;260(28):15204-10.
1984: Kamel Khalili; roberto weinmann
Actin mRNAs in HeLa cells. Stabilization after adenovirus infection.
Journal of molecular biology 1984;180(4):1007-21.
1984: R Zandomeni; roberto weinmann
Inhibitory effect of 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole on a protein kinase.
The Journal of biological chemistry 1984;259(23):14804-11.
1984: M F Concino; R F Lee; J P Merryweather; roberto weinmann
The adenovirus major late promoter TATA box and initiation site are both necessary for transcription in vitro.
Nucleic acids research 1984;12(19):7423-33.
1984: Kamel Khalili; roberto weinmann
Shut-off of actin biosynthesis in adenovirus serotype-2-infected cells.
Journal of molecular biology 1984;175(4):453-68.
1984: roberto weinmann; S Ackerman; D Bunick; M Concino; R Zandomeni
In vitro transcription of adenovirus genes.
Current topics in microbiology and immunology 1984;109():125-45.
1983: S Ackerman; D Bunick; R Zandomeni; roberto weinmann
RNA polymerase II ternary transcription complexes generated in vitro.
Nucleic acids research 1983;11(17):6041-64.
1983: M Concino; R A Goldman; M H Caruthers; roberto weinmann
Point mutations of the adenovirus major late promoter with different transcriptional efficiencies in vitro.
The Journal of biological chemistry 1983;258(13):8493-6.
1983: R Zandomeni; D Bunick; S Ackerman; B Mittleman; roberto weinmann
Mechanism of action of DRB. III. Effect on specific in vitro initiation of transcription.
Journal of molecular biology 1983;167(3):561-74.