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Alexander Shepherd

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TOP 3
Jay N Cohn; Gordon T McInnes; Alexander Shepherd
Direct-acting vasodilators.
JD Gray; D Danoff; Alexander Shepherd
Clinical pharmacology education: looking into the future.
Thomas G Pickering; Alexander Shepherd; Ian Puddey; Dale B Glasser; John Orazem; Nancy Sherman; Giuseppe Mancia
Sildenafil citrate for erectile dysfunction in men receiving multiple antihypertensive agents: a randomized controlled trial.

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All Publications

2011: Jay N Cohn; Gordon T McInnes; Alexander Shepherd
Direct-acting vasodilators.
Journal of clinical hypertension (Greenwich, Conn.) 2011;13(9):690-2.
2007: JD Gray; D Danoff; Alexander Shepherd
Clinical pharmacology education: looking into the future.
Clinical pharmacology and therapeutics 2007;81(2):305-8.
2004: Thomas G Pickering; Alexander Shepherd; Ian Puddey; Dale B Glasser; John Orazem; Nancy Sherman; Giuseppe Mancia
Sildenafil citrate for erectile dysfunction in men receiving multiple antihypertensive agents: a randomized controlled trial.
American journal of hypertension 2004;17(12 Pt 1):1135-42.
2003: Alexander Shepherd
A clinical pharmacologist's response to Dr Milton Packer's perspective on the results of the COMET trial.
Journal of cardiac failure 2003;9(6):454-7.
2000: G Stagni; D O'Donnell; YJ Liu; Dean Kellogg; T Morgan; Alexander Shepherd
Intradermal microdialysis: kinetics of iontophoretically delivered propranolol in forearm dermis.
Journal of controlled release : official journal of the Controlled Release Society 2000;63(3):331-9.
1999: Addison A Taylor; Alexander Shepherd; William J Polvino; R Mangoo-Karim; K Ballard; S Sunthornyothin; R R Luther; James L Pool
Prolonged fenoldopam infusions in patients with mild to moderate hypertension: pharmacodynamic and pharmacokinetic effects.
American journal of hypertension 1999;12(9 Pt 1):906-14.
1999: Alexander Shepherd; A J Atkinson
Report from the American Board of Clinical Pharmacology.
Clinical pharmacology and therapeutics 1999;65(4):355-6.
1999: G Stagni; D O'Donnell; YJ Liu; Dean Kellogg; Alexander Shepherd
Iontophoretic current and intradermal microdialysis recovery in humans.
Journal of pharmacological and toxicological methods 1999;41(1):49-54.
1998: Dun-Xian Tan; Lucien C Manchester; Russel J Reiter; Benjamin F Plummer; L Jean Hardies; Susan Weintraub; Alexander Shepherd
A novel melatonin metabolite, cyclic 3-hydroxymelatonin: a biomarker of in vivo hydroxyl radical generation.
Biochemical and biophysical research communications 1998;253(3):614-20.
1998: Dean Kellogg; S R Morris; S B Rodriguez; Yanjuan Liu; M Grossmann; G Stagni; Alexander Shepherd
Thermoregulatory reflexes and cutaneous active vasodilation during heat stress in hypertensive humans.
Journal of applied physiology (Bethesda, Md. : 1985) 1998;85(1):175-80.
1998: YJ Liu; G Stagni; J G Walden; Alexander Shepherd; Michael Lichtenstein
Thioridazine dose-related effects on biomechanical force platform measures of sway in young and old men.
Journal of the American Geriatrics Society 1998;46(4):431-7.
1997: Suzanne Oparil; Isaac Kobrin; Darrell R. Abernethy; B S Levine; M C Reif; Alexander Shepherd
Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension.
American journal of hypertension 1997;10(7 Pt 1):735-42.
1997: G Stagni; Alexander Shepherd; Y Liu; W R Gillespie
Bioavailability assessment from pharmacologic data: method and clinical evaluation.
Journal of pharmacokinetics and biopharmaceutics 1997;25(3):349-62.
1997: G Stagni; Alexander Shepherd; Y Liu; W R Gillespie
New mathematical implementation of generalized pharmacodynamic models: method and clinical evaluation.
Journal of pharmacokinetics and biopharmaceutics 1997;25(3):313-48.
1997: JS Alpert; Isaac Kobrin; V DeQuattro; R Friedman; Alexander Shepherd; P E Fenster; U Thadani
Additional antianginal and anti-ischemic efficacy of mibefradil in patients pretreated with a beta blocker for chronic stable angina pectoris.
The American journal of cardiology 1997;79(8):1025-30.
1997: MJ Jamieson; G M Gonzales; T I Jackson; S M Koerth; W F Romano; D X Tan; F Castillon; M H Skinner; M Grossmann; Alexander Shepherd
Evaluation of the IITC tail cuff blood pressure recorder in the rat against intraarterial pressure according to criteria for human devices.
American journal of hypertension 1997;10(2):209-16.
1995: M Grossmann; MJ Jamieson; Dean Kellogg; W A Kosiba; P E Pergola; C G Crandall; Alexander Shepherd
The effect of iontophoresis on the cutaneous vasculature: evidence for current-induced hyperemia.
Microvascular research 1995;50(3):444-52.
1995: MJ Jamieson; L Garbutt-Sculli; Alexander Shepherd
Miscompliance by proxy.
Clinical pharmacology and therapeutics 1995;58(5):594.
1995: Alexander Shepherd
Value of different methods for characterizing cardiovascular drug effects.
European journal of clinical investigation 1995;25 Suppl 1():29-34.
1993: Darrell R. Abernethy; Alexander Shepherd; D W Nierenberg
Clinical pharmacologists and health care reform: contributing to the debate.
Clinical pharmacology and therapeutics 1993;54(2):123-5.
1992: P A Carberry; Alexander Shepherd; John M Johnson
Resting and maximal forearm skin blood flows are reduced in hypertension.
Hypertension 1992;20(3):349-55.
1992: J R Woodworth; T M Ludden; L K Ludden; Alexander Shepherd; K S Rotenberg
Comparative bioavailability of a sustained-release ion-exchange hydralazine product with a potassium (cation) challenge.
Journal of pharmaceutical sciences 1992;81(6):541-2.
1991: Alexander Shepherd; C LeForce; G D Park; R S Hoop; S Weir
The determinants of response to diltiazem in hypertension.
Clinical pharmacology and therapeutics 1991;50(3):338-49.
1991: William B Applegate; H L Phillips; H Schnaper; Alexander Shepherd; D Schocken; J C Luhr; Gary G Koch; G D Park
A randomized controlled trial of the effects of three antihypertensive agents on blood pressure control and quality of life in older women.
Archives of internal medicine 1991;151(9):1817-23.
1991: Alexander Shepherd; C M Kwan; C L Brodie; MJ Jamieson
Determination of alpha-adrenergic blocking potency.
Clinical pharmacology and therapeutics 1991;49(1):69-77.
1990: Alexander Shepherd
A perspective on the American Board of Clinical Pharmacology, Inc.
Journal of clinical pharmacology 1990;30(12):1058-9.
1990: Alexander Shepherd
A perspective on the American Board of Clinical Pharmacology, Inc.
Clinical pharmacology and therapeutics 1990;48(6):611-2.
1990: S H Jackson; Alexander Shepherd; T M Ludden; MJ Jamieson; J Woodworth; D Rogers; L K Ludden; K T Muir
Effect of food on oral availability of apresoline and controlled release hydralazine in hypertensive patients.
Journal of cardiovascular pharmacology 1990;16(4):624-8.
1990: Yui-Wing Lam; Alexander Shepherd
Drug interactions in hypertensive patients. Pharmacokinetic, pharmacodynamic and genetic considerations.
Clinical pharmacokinetics 1990;18(4):295-317.
1989: Alexander Shepherd; Albert A Carr; M Davidov; J Hamilton; H Schnaper; M Velasquez; B Brockway; Louis Michael Prisant; B Hamilton; L Gonasun
Efficacy and safety of isradipine in hypertension.
Journal of cardiovascular pharmacology 1989;13(4):580-5.
1989: C M Kwan; Alexander Shepherd; John M Johnson; W F Taylor; B A Brockway
Forearm and finger hemodynamics, blood pressure control, and lipid changes in diabetic hypertensive patients treated with atenolol and prazosin. A brief report.
The American journal of medicine 1989;86(1B):55-8.
1988: T M Ludden; K S Rotenberg; L K Ludden; Alexander Shepherd; J R Woodworth
Relative bioavailability of immediate- and sustained-release hydralazine formulations.
Journal of pharmaceutical sciences 1988;77(12):1026-32.
1988: MJ Jamieson; Alexander Shepherd; S H Jackson; S S Patel; P H Flanagan; H Galbraith
Alpha adrenergic blocking activity of urapidil in man.
Research communications in chemical pathology and pharmacology 1988;62(2):173-85.
1988: Alexander Shepherd
Determinants of antihypertensive response to calcium antagonists in systemic hypertension.
The American journal of cardiology 1988;62(11):92G-96G.
1988: C M Kwan; Alexander Shepherd; John M Johnson; W F Taylor
Forearm and finger hemodynamics, blood pressure control, and lipid changes in patients with diabetic hypertension treated with atenolol and prazosin.
Clinical pharmacology and therapeutics 1988;44(2):202-10.
1988: Alexander Shepherd
Human pharmacology of urapidil.
Drugs 1988;35 Suppl 6():34-9.
1987: S H Jackson; MJ Jamieson; A Johnston; Alexander Shepherd
The analysis of dose-response curves--a practical approach.
British journal of clinical pharmacology 1987;23(2):199-205.
1987: R L Miller; C Winograd; D Frengley; R A Tsukuda; P Katz; P Barry; Alexander Shepherd; L Cooney
Inpatient geriatric consultative teams.
Gerontology & geriatrics education 1987;8(1-2):35-52.
1986: M S Elfellah; A Johns; Alexander Shepherd
Effect of age on responsiveness of isolated rat atria to carbachol and on binding characteristics of atrial muscarinic receptors.
Journal of cardiovascular pharmacology 1986;8(4):873-7.
1986: Alexander Shepherd; N A Irvine
Differential hemodynamic and sympathoadrenal effects of sodium nitroprusside and hydralazine in hypertensive subjects.
Journal of cardiovascular pharmacology 1986;8(3):527-33.
1986: MJ Jamieson; S H Jackson; S S Patel; Alexander Shepherd; H Galbraith; W Stewart; P H Flanagan
The assessment of the beta-blocking activity of urapidil: a new method.
European journal of clinical pharmacology 1986;31(2):149-54.
1985: G A Gates; J Saegert; N Wilson; L Johnson; Alexander Shepherd; E M Hearne
Effect of beta blockade on singing performance.
The Annals of otology, rhinology, and laryngology 1985;94(6 Pt 1):570-4.
1985: A Amador; R W Steger; A Bartke; A Johns; T M Siler-Khodr; C R Parker; Alexander Shepherd
Testicular LH receptors during aging in Fisher 344 rats.
Journal of andrology 1985;6(1):61-4.
1985: R W Steger; L V De Paolo; Alexander Shepherd
Effects of advancing age on hypothalamic neurotransmitter content and on basal and norepinephrine-stimulated LHRH release.
Neurobiology of aging 1985;6(2):113-6.
1984: Alexander Shepherd; N A Irvine; T M Ludden; M S Lin; J L McNay
Effect of oral dose size on hydralazine kinetics and vasodepressor response.
Clinical pharmacology and therapeutics 1984;36(5):595-600.
1984: N A Irvine; Alexander Shepherd
Age and blood pressure determine vasodepressor response to sodium nitroprusside.
Journal of cardiovascular pharmacology 1984;6(5):816-21.
1984: Alexander Shepherd; N A Irvine; T M Ludden
Effect of food on blood hydralazine levels and response in hypertension.
Clinical pharmacology and therapeutics 1984;36(1):14-8.
1984: John M Johnson; W F Taylor; Alexander Shepherd; M K Park
Laser-Doppler measurement of skin blood flow: comparison with plethysmography.
Journal of applied physiology: respiratory, environmental and exercise physiology 1984;56(3):798-803.
1984: Alexander Shepherd; W Pinkley; M S Lin; J L McNay; T K Keeton
Activation of the renin-angiotensin system by sodium nitroprusside in essential hypertension.
Journal of cardiovascular pharmacology 1984;6(1):201-5.
1983: N A Irvine; Alexander Shepherd; M P Lynn
A non-invasive off-line method of measuring cardiac output.
Research communications in chemical pathology and pharmacology 1983;42(2):311-30.
1983: Alexander Shepherd; T C Hardin; T M Ludden; D J Miner; D L Coleman
Latamoxef (moxalactam) kinetics in volunteers studied by a specific HPLC assay technique.
The Journal of antimicrobial chemotherapy 1983;12(4):377-86.
1983: M S Lin; J L McNay; Alexander Shepherd; T K Keeton
Effects of hydralazine and sodium nitroprusside on plasma catecholamines and heart rate.
Clinical pharmacology and therapeutics 1983;34(4):474-80.
1983: M S Lin; J L McNay; Alexander Shepherd; T K Keeton
The response of plasma catecholamines to intravenous labetalol: a comparison with sodium nitroprusside.
Clinical pharmacology and therapeutics 1983;34(4):466-73.
1983: T M Ludden; Alexander Shepherd; J L McNay; M S Lin
Effect of intravenous dose on hydralazine kinetics after administration.
Clinical pharmacology and therapeutics 1983;34(2):148-52.
1983: M S Lin; J L McNay; Alexander Shepherd; G E Musgrave; T K Keeton
Increased plasma norepinephrine accompanies persistent tachycardia after hydralazine.
Hypertension 1983;5(2):257-63.
1983: Alexander Shepherd; M S Lin; J L McNay; G E Musgrave; T K Keeton
Baroreflex sensitivity modulates vasodepressor response to nitroprusside.
Hypertension 1983;5(1):79-85.
1983: J Feely; S McLaren; Alexander Shepherd; D Maclean; I H Stevenson; C G Swift; T E Isles
Antithyroid effect of chlorpropamide?
Human toxicology 1983;2(1):149-53.
1982: T M Ludden; J L McNay; Alexander Shepherd; M S Lin
Clinical pharmacokinetics of hydralazine.
Clinical pharmacokinetics 1982;7(3):185-205.
1981: Alexander Shepherd; M S Lin; T K Keeton; J L McNay
Plasma noradrenaline as a measure of baroreflex sensitivity in hypertensive man.
Clinical science (London, England : 1979) 1981;61 Suppl 7():165s-168s.
1981: Alexander Shepherd; M S Lin; J McNay; T Ludden; G Musgrave
Determinants of response to intravenous hydralazine in hypertension.
Clinical pharmacology and therapeutics 1981;30(6):773-81.
1981: Alexander Shepherd; J L McNay; T M Ludden; M S Lin; G E Musgrave
Plasma concentration and acetylator phenotype determine response to oral hydralazine.
Hypertension 1981;3(5):580-5.
1981: T M Ludden; J L McNay; Alexander Shepherd; M S Lin
Variability of plasma hydralazine concentrations in male hypertensive patients.
Arthritis and rheumatism 1981;24(8):987-93.
1981: D J Miner; D L Coleman; Alexander Shepherd; T C Hardin
Determination of moxalactam in human body fluids by liquid chromatographic and microbiological methods.
Antimicrobial agents and chemotherapy 1981;20(2):252-7.
1981: Alexander Shepherd; M S Lin; T K Keeton
Hypoglycemia-induced hypertension in a diabetic patient on metoprolol.
Annals of internal medicine 1981;94(3):357-8.
1981: T Talseth; J L McNay; K Ballinger; W A Clementi; Alexander Shepherd
Vasoconstriction limits to the use of the central ear artery pressure in conscious rabbits.
Laboratory animals 1981;15(1):1-3.
1981: K D Haegele; T Talseth; H B Skrdlant; Alexander Shepherd; S L Huff
Determination of hydralazine pyruvic acid hydrazone and its correlation with "apparent" hydralazine.
Arzneimittel-Forschung 1981;31(2):357-62.
1980: Alexander Shepherd; T M Ludden; J L McNay; M S Lin
Hydralazine kinetics after single and repeated oral doses.
Clinical pharmacology and therapeutics 1980;28(6):804-11.
1980: T M Ludden; Alexander Shepherd; J L McNay; M S Lin
Hydralazine kinetics in hypertensive patients after intravenous administration.
Clinical pharmacology and therapeutics 1980;28(6):736-42.
1980: K D Haegele; H B Skrdlant; T Talseth; J L McNay; Alexander Shepherd; W A Clementi
Quantitative analysis of hydralazine pyruvic acid hydrazone, the major plasma metabolite of hydralazine.
Journal of chromatography 1980;187(1):171-9.
1979: T Talseth; K D Haegele; J L McNay; H B Skrdlant; W A Clementi; Alexander Shepherd
Pharmacokinetics and cardiovascular effects in rabbits of a major hydralazine metabolite, the hydralazine pyruvic-acid hydrazone.
The Journal of pharmacology and experimental therapeutics 1979;211(3):509-13.
1979: T M Ludden; L K Goggin; J L McNay; K D Haegele; Alexander Shepherd
High-pressure liquid chromatographic assay for hydralazine in human plasma.
Journal of pharmaceutical sciences 1979;68(11):1423-5.
1979: Alexander Shepherd; T M Ludden; K D Haegele; T Talseth; J L McNay
Pharmacokinetics of hydralazine, apparent hydralazine and hydralazine pyruvic acid hydrazone in humans.
Research communications in chemical pathology and pharmacology 1979;26(1):129-44.
1978: D P Nicholls; Alexander Shepherd
Altered warfarin metabolism in iron-deficient patient.
Lancet 1978;2(8082):215-6.
1978: S A Salem; P Rajjayabun; Alexander Shepherd; I H Stevenson
Reduced induction of drug metabolism in the elderly.
Age and ageing 1978;7(2):68-73.
1978: L J Christopher; B R Ballinger; Alexander Shepherd; A Ramsay; G Crooks
Drug prescribing patterns in the elderly: a cross-sectional study of in-patients.
Age and ageing 1978;7(2):74-82.
1977: Alexander Shepherd; D S Hewick; T A Moreland; I H Stevenson
Age as a determinant of sensitivity to warfarin.
British journal of clinical pharmacology 1977;4(3):315-20.
1976: J J Manns; Alexander Shepherd; J Crooks; D G Adamson
Measurement of cardiac muscle relaxation in hypothyroidism.
British medical journal 1976;1(6022):1366-8.
1976: D S Hewick; Alexander Shepherd
The plasma elimination of the enantiomers of phenprocoumon in man.
The Journal of pharmacy and pharmacology 1976;28(3):257-8.
1976: W K Stewart; L W Fleming; Alexander Shepherd
Haemoglobin and serum iron responses to periodic intravenous iron-dextran infusions during maintenance haemodialysis.
Nephron 1976;17(2):121-9.
1975: J Crooks; Alexander Shepherd; I H Stevenson
Drugs and the elderly. The nature of the problem.
Health bulletin 1975;33(5):222-7.
1975: J R Evans; Alexander Shepherd
The effect of desferrioxamine on the colorimetric determination of iron in human serum and plasma.
Clinica chimica acta; international journal of clinical chemistry 1975;60(3):401-4.
1974: Alexander Shepherd; W K Stewart; B Thjodleifsson; K G Wormsley
Further studies of gastric hypersecretion in chronic renal failure.
British medical journal 1974;1(5898):96-8.
1973: Alexander Shepherd; W K Stewart; K G Wormsley
Peptic ulceration in chronic renal failure.
Lancet 1973;1(7816):1357-9.