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Babatunde Oyajobi

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Rongrong Zhang; Di Chen; Hong-Wen Deng; Stephen E Harris; Babatunde Oyajobi; Christopher Tsao; Ming Zhao
Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts.
Daniel J Dairaghi; Anjana Gupta; Brandon McCluskey; Shichang Miao; Babatunde Oyajobi; Jay P Powers; Thomas J Schall; Lisa C Seitz; Yu Wang; Yibin Zeng; Penglie Zhang; Juan C Jaen
CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease.
Kevin Robert Kelly; Deva Mahalingam; Babatunde Oyajobi; Jennifer Carew; M Coffey; C M Espitia; Francis Giles; Steffan Nawrocki
Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma.

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2013: Rongrong Zhang; Di Chen; Hong-Wen Deng; Stephen E Harris; Babatunde Oyajobi; Christopher Tsao; Ming Zhao
Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts.
Bone 2013;52(1):145-56.
2012: Daniel J Dairaghi; Anjana Gupta; Brandon McCluskey; Shichang Miao; Babatunde Oyajobi; Jay P Powers; Thomas J Schall; Lisa C Seitz; Yu Wang; Yibin Zeng; Penglie Zhang; Juan C Jaen
CCR1 blockade reduces tumor burden and osteolysis in vivo in a mouse model of myeloma bone disease.
Blood 2012;120(7):1449-57.
2012: Kevin Robert Kelly; Deva Mahalingam; Babatunde Oyajobi; Jennifer Carew; M Coffey; C M Espitia; Francis Giles; Steffan Nawrocki
Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma.
Oncogene 2012;31(25):3023-38.
2012: Hongbin Liu; Babatunde Oyajobi; Rongrong Zhang; Di Chen; Ming Zhao
Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiation.
Journal of cellular physiology 2012;227(3):952-63.
2012: Bokyung Sung; Babatunde Oyajobi; Bharat B Aggarwal
Plumbagin inhibits osteoclastogenesis and reduces human breast cancer-induced osteolytic bone metastasis in mice through suppression of RANKL signaling.
Molecular cancer therapeutics 2012;11(2):350-9.
2011: Hongbin Liu; Babatunde Oyajobi; Christopher J Papasian; Rongrong Zhang; Shujun Zhang; Hong-Wen Deng; Seon-Yle Ko; Ming Zhao
Microtubule assembly affects bone mass by regulating both osteoblast and osteoclast functions: stathmin deficiency produces an osteopenic phenotype in mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2011;26(9):2052-67.
2011: Keitaro Sou; Beth Goins; Babatunde Oyajobi; bruno travi; William Phillips
Bone marrow-targeted liposomal carriers.
Expert opinion on drug delivery 2011;8(3):317-28.
2011: Rachelle W Johnson; Mai P Nguyen; Susan Padalecki; Barry Grubbs; Alyssa R Merkel; Babatunde Oyajobi; Lynn M Matrisian; Gregory R Mundy; Julie A Sterling
TGF-beta promotion of Gli2-induced expression of parathyroid hormone-related protein, an important osteolytic factor in bone metastasis, is independent of canonical Hedgehog signaling.
Cancer research 2011;71(3):822-31.
2011: Rongrong Zhang; Hong-Wen Deng; Shanshan Dong; James R Edwards; Seon-Yle Ko; Hongbin Liu; Babatunde Oyajobi; Christopher Papasian; Ming Zhao
Transcriptional regulation of BMP2 expression by the PTH-CREB signaling pathway in osteoblasts.
PloS one 2011;6(6):e20780.
2009: Claire M Edwards; Seint T Lwin; Jessica A Fowler; Babatunde Oyajobi; Junling Zhuang; Andreia L Bates; Gregory R Mundy
Myeloma cells exhibit an increase in proteasome activity and an enhanced response to proteasome inhibition in the bone marrow microenvironment in vivo.
American journal of hematology 2009;84(5):268-72.
2009: Keitaro Sou; Babatunde Oyajobi; Beth Goins; William Phillips; Eishun Tsuchida
Characterization and cytotoxicity of self-organized assemblies of curcumin and amphiphatic poly(ethylene glycol).
Journal of biomedical nanotechnology 2009;5(2):202-8.
2009: Ming Zhao; Seon-Yle Ko; Jin-Hua Liu; Di Chen; Jianghong Zhang; Baolin Wang; Stephen E Harris; Babatunde Oyajobi; Gregory R Mundy
Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2.
Molecular and cellular biology 2009;29(5):1291-305.
2009: Bokyung Sung; Akira Murakami; Babatunde Oyajobi; Bharat B Aggarwal
Zerumbone abolishes RANKL-induced NF-kappaB activation, inhibits osteoclastogenesis, and suppresses human breast cancer-induced bone loss in athymic nude mice.
Cancer research 2009;69(4):1477-84.
2008: Oihana Murillo; Ainhoa Arina; Sandra Hervas-Stubbs; Anjana Gupta; Brandon McCluskey; Juan Dubrot; Asís Palazón; Arantza Azpilikueta; Maria C Ochoa; Carlos Alfaro; Sarai Solano; José L Pérez-Gracia; Babatunde Oyajobi; Ignacio Melero
Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(21):6895-906.
2008: Claire M Edwards; James R Edwards; Seint T Lwin; Javier Esparza; Babatunde Oyajobi; Brandon McCluskey; Steven Munoz; Barry Grubbs; Gregory R Mundy
Increasing Wnt signaling in the bone marrow microenvironment inhibits the development of myeloma bone disease and reduces tumor burden in bone in vivo.
Blood 2008;111(5):2833-42.
2007: Babatunde Oyajobi; I Ross Garrett; Anjana Gupta; Alda Flores; Javier Esparza; Steve Muñoz; Ming Zhao; Gregory R Mundy
Stimulation of new bone formation by the proteasome inhibitor, bortezomib: implications for myeloma bone disease.
British journal of haematology 2007;139(3):434-8.
2007: Babatunde Oyajobi; Steve Muñoz; Rami Kakonen; Paul J Williams; Anjana Gupta; Christi L Wideman; Beryl Story; Barry Grubbs; Allison Armstrong; William C Dougall; I Ross Garrett; Gregory R Mundy
Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging.
Molecular cancer therapeutics 2007;6(6):1701-8.
2007: Babatunde Oyajobi
Multiple myeloma/hypercalcemia.
Arthritis research & therapy 2007;9 Suppl 1():S4.
2006: Julie A Sterling; Babatunde Oyajobi; Barry Grubbs; Susan Padalecki; Steve A Munoz; Anjana Gupta; Beryl Story; Ming Zhao; Gregory R Mundy
The hedgehog signaling molecule Gli2 induces parathyroid hormone-related peptide expression and osteolysis in metastatic human breast cancer cells.
Cancer research 2006;66(15):7548-53.
2006: Ming Zhao; Mei Qiao; Stephen E Harris; Di Chen; Babatunde Oyajobi; Gregory R Mundy
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.
Molecular and cellular biology 2006;26(16):6197-208.
2005: Claire M Shipman; Babatunde Oyajobi; Gregory R Mundy
Advances in the management of myeloma bone disease.
Expert opinion on pharmacotherapy 2005;6(16):2781-91.
2004: Ming Zhao; Mei Qiao; Stephen E Harris; Babatunde Oyajobi; Gregory R Mundy; Di Chen
Smurf1 inhibits osteoblast differentiation and bone formation in vitro and in vivo.
The Journal of biological chemistry 2004;279(13):12854-9.
2003: Ming Zhao; Mei Qiao; Babatunde Oyajobi; Gregory R Mundy; Di Chen
E3 ubiquitin ligase Smurf1 mediates core-binding factor alpha1/Runx2 degradation and plays a specific role in osteoblast differentiation.
The Journal of biological chemistry 2003;278(30):27939-44.
2003: Babatunde Oyajobi; Giovanni Franchin; Paul J Williams; Donna Pulkrabek; Anjana Gupta; Steve Munoz; Barry Grubbs; Ming Zhao; Di Chen; Barbara Sherry; Gregory R Mundy
Dual effects of macrophage inflammatory protein-1alpha on osteolysis and tumor burden in the murine 5TGM1 model of myeloma bone disease.
Blood 2003;102(1):311-9.
2003: Babatunde Oyajobi; Gregory R Mundy
Receptor activator of NF-kappaB ligand, macrophage inflammatory protein-1alpha, and the proteasome: novel therapeutic targets in myeloma.
Cancer 2003;97(3 Suppl):813-7.
2003: Suresh Mohla; Katherine N Weilbacher; Michael L Cher; Babatunde Oyajobi; Catherine Van Poznak; Dennis R Clohisy
Third North American Symposium on Skeletal Complications of Malignancy: summary of the scientific sessions.
Cancer 2003;97(3 Suppl):719-25.
2001: Babatunde Oyajobi; D M Anderson; K Traianedes; Paul J Williams; Toshiyuki Yoneda; Gregory R Mundy
Therapeutic efficacy of a soluble receptor activator of nuclear factor kappaB-IgG Fc fusion protein in suppressing bone resorption and hypercalcemia in a model of humoral hypercalcemia of malignancy.
Cancer research 2001;61(6):2572-8.
2001: Souhila Ahdjoudj; Françoise Lasmoles; Babatunde Oyajobi; Abderrahim Lomri; P Delannoy; Pierre J Marie
Reciprocal control of osteoblast/chondroblast and osteoblast/adipocyte differentiation of multipotential clonal human marrow stromal F/STRO-1(+) cells.
Journal of cellular biochemistry 2001;81(1):23-38.
2000: Babatunde Oyajobi; Jian-Hong Deng; Sarah L Dallas; Hal B Jenson; Gregory R Mundy; Shou-Jiang Gao
Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma.
British journal of haematology 2000;109(2):413-9.
2000: Abdullah Karadag; Babatunde Oyajobi; JF Apperley; R Graham G Russell; Peter I Croucher
Human myeloma cells promote the production of interleukin 6 by primary human osteoblasts.
British journal of haematology 2000;108(2):383-90.
1999: P Liu; Babatunde Oyajobi; R Graham G Russell; Andrew Scutt
Regulation of osteogenic differentiation of human bone marrow stromal cells: interaction between transforming growth factor-beta and 1,25(OH)(2) vitamin D(3) In vitro.
Calcified tissue international 1999;65(2):173-80.
1999: Sarah L Dallas; I Ross Garrett; Babatunde Oyajobi; Mark Dallas; B F Boyce; F Bauss; J Radl; Gregory R Mundy
Ibandronate reduces osteolytic lesions but not tumor burden in a murine model of myeloma bone disease.
Blood 1999;93(5):1697-706.
1999: Babatunde Oyajobi; Abderrahim Lomri; M Hott; Pierre J Marie
Isolation and characterization of human clonogenic osteoblast progenitors immunoselected from fetal bone marrow stroma using STRO-1 monoclonal antibody.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(3):351-61.
1998: Babatunde Oyajobi; Astrid Frazer; Anthony P Hollander; R M Graveley; C Xu; Adam Houghton; Paul Hatton; R Graham G Russell; Bradley Stringer
Expression of type X collagen and matrix calcification in three-dimensional cultures of immortalized temperature-sensitive chondrocytes derived from adult human articular cartilage.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(3):432-42.
1998: Adam Houghton; Babatunde Oyajobi; George A Foster; R Graham G Russell; Bradley Stringer
Immortalization of human marrow stromal cells by retroviral transduction with a temperature sensitive oncogene: identification of bipotential precursor cells capable of directed differentiation to either an osteoblast or adipocyte phenotype.
Bone 1998;22(1):7-16.
1996: C Xu; Babatunde Oyajobi; A Frazer; LD Kozaci; R Graham G Russell; Anthony P Hollander
Effects of growth factors and interleukin-1 alpha on proteoglycan and type II collagen turnover in bovine nasal and articular chondrocyte pellet cultures.
Endocrinology 1996;137(8):3557-65.
1996: J S Price; Babatunde Oyajobi; A M Nalin; A Frazer; R Graham G Russell; Linda J Sandell
Chondrogenesis in the regenerating antler tip in red deer: expression of collagen types I, IIA, IIB, and X demonstrated by in situ nucleic acid hybridization and immunocytochemistry.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;205(3):332-47.
1994: J S Price; Babatunde Oyajobi; R O Oreffo; R Graham G Russell
Cells cultured from the growing tip of red deer antler express alkaline phosphatase and proliferate in response to insulin-like growth factor-I.
The Journal of endocrinology 1994;143(2):R9-16.
1994: Babatunde Oyajobi; R Graham G Russell; A M Caswell
Modulation of ecto-nucleoside triphosphate pyrophosphatase activity of human osteoblast-like bone cells by 1 alpha,25-dihydroxyvitamin D3, 24R,25-dihydroxyvitamin D3, parathyroid hormone, and dexamethasone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(8):1259-66.
1994: J S Price; Babatunde Oyajobi; R Graham G Russell
The cell biology of bone growth.
European journal of clinical nutrition 1994;48 Suppl 1():S131-49.
1994: Babatunde Oyajobi; A M Caswell; R Graham G Russell
Transforming growth factor beta increases ecto-nucleoside triphosphate pyrophosphatase activity of human bone-derived cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(1):99-109.
1992: F W Fawthrop; Babatunde Oyajobi; R A D Bunning; R Graham G Russell
The effect of transforming growth factor beta on the plasminogen activator activity of normal human osteoblast-like cells and a human osteosarcoma cell line MG-63.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1992;7(12):1363-71.