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MARSHA WILLS-KARP

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Dianer Yang; Jessica M Baumann; R Scott Dunn; Daniel A Lawrence; Diana M Lindquist; Niza Nemkul; Ahmed Shereen; Yu-Yo Sun; MARSHA WILLS-KARP; Chia-Yi Kuan
Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.
MARSHA WILLS-KARP; Paul J Bryce; Krista Dienger; Fred D Finkelman; James G Fox; Gurjit K Khurana Hershey; Evelyn A Kurt-Jones; Lauren Lewis; Ian Lewkowich; Charles Perkins; Reena Rani; Umasundari Sivaprasad; Dirk E Smith; Timothy C Wang; De'Broski R Herbert
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.
MARSHA WILLS-KARP; Fred D Finkelman
Innate lymphoid cells wield a double-edged sword.

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2013: Dianer Yang; Jessica M Baumann; R Scott Dunn; Daniel A Lawrence; Diana M Lindquist; Niza Nemkul; Ahmed Shereen; Yu-Yo Sun; MARSHA WILLS-KARP; Chia-Yi Kuan
Plasminogen activator inhibitor-1 mitigates brain injury in a rat model of infection-sensitized neonatal hypoxia-ischemia.
Cerebral cortex (New York, N.Y. : 1991) 2013;23(5):1218-29.
2012: MARSHA WILLS-KARP; Paul J Bryce; Krista Dienger; Fred D Finkelman; James G Fox; Gurjit K Khurana Hershey; Evelyn A Kurt-Jones; Lauren Lewis; Ian Lewkowich; Charles Perkins; Reena Rani; Umasundari Sivaprasad; Dirk E Smith; Timothy C Wang; De'Broski R Herbert
Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.
The Journal of experimental medicine 2012;209(3):607-22.
2011: MARSHA WILLS-KARP; Fred D Finkelman
Innate lymphoid cells wield a double-edged sword.
Nature immunology 2011;12(11):1025-7.
2011: Yui-Hsi Wang; MARSHA WILLS-KARP
The potential role of interleukin-17 in severe asthma.
Current allergy and asthma reports 2011;11(5):388-94.
2011: Eric M Schauberger; Max A Seibold; Hongmei Zhang; Julie T Ziegler; S Hasan Arshad; Pedro C Avila; Sheila J Barton; Esteban González Burchard; Susan L Ewart; Karen H Friderici; Christopher Gignoux; Qutayba Hamid; Isaac T W Harley; John B Harley; Stephen T Holgate; John W Holloway; Donglei Hu; Marianne Huebner; Wilfried Karmaus; Jeffrey R Kilpatrick; Ramesh J Kurukulaaratchy; Stephane Lajoie-Kadoch; Carl D Langefeld; Stephanie J London; William Rodriguez-Cintrón; Jose R Rodriguez-Santana; Isabelle Romieu; Matthew J Rose-Zerilli; MARSHA WILLS-KARP
Identification of ATPAF1 as a novel candidate gene for asthma in children.
The Journal of allergy and clinical immunology 2011;128(4):753-760.e11.
2011: Kathy T Schroer; Umasundari Sivaprasad; Keith F Stringer; MARSHA WILLS-KARP; Stacey A Bass; Lou Ann S Brown; Mark B Ericksen; Anne M Fitzpatrick; Aaron M Gibson; Tim Lecras; Gurjit K Khurana Hershey
Downregulation of glutathione S-transferase pi in asthma contributes to enhanced oxidative stress.
The Journal of allergy and clinical immunology 2011;128(3):539-48.
2011: Javid P Mohammed; Carolyn Moule; Laurence B Peterson; Dan Rainbow; William M Ridgway; Paul B Savage; John A Todd; Linda S Wicker; MARSHA WILLS-KARP; Jan Clark; Heather I Fraser; Michael E Fusakio; Jochen Mattner
Identification of Cd101 as a susceptibility gene for Novosphingobium aromaticivorans-induced liver autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(1):337-49.
2011: James A Stefater; Bart Williams; MARSHA WILLS-KARP; Terry Yamaguchi; Rieko Ajima; Adam R Burr; April C Carpenter; Jieqing Fan; Napoleone Ferrara; Holger Gerhardt; Ian Lewkowich; Giovanni Mariggi; Jeffery D Molkentin; Jeffrey W Pollard; Sujata Rao; Richard Lang
Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.
Nature 2011;474(7352):511-5.
2011: Charles Perkins; Noriko Yanase; George Smulian; Lucy Gildea; Tatyana Orekov; Crystal Potter; Frank Brombacher; Bruce Aronow; MARSHA WILLS-KARP; Fred D Finkelman
Selective stimulation of IL-4 receptor on smooth muscle induces airway hyperresponsiveness in mice.
The Journal of experimental medicine 2011;208(4):853-67.
2011: Meredith CHRISTINE McCormack; Patrick N Breysse; Elizabeth C Matsui; Nadia N Hansel; Roger D Peng; Jean Curtin-Brosnan; D'Ann Williams; MARSHA WILLS-KARP; Gregory B Diette
Indoor particulate matter increases asthma morbidity in children with non-atopic and atopic asthma.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2011;106(4):308-15.
2011: Ian Lewkowich; Scottie B Day; Krista Dienger; John R Ledford; MARSHA WILLS-KARP; Ping Zhou; Kristen Page
Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation.
Respiratory research 2011;12():122.
2011: Fukun Guo; Shuangmin Zhang; Pulak Tripathi; Jochen Mattner; James Phelan; Alyssa Sproles; Jun Mo; MARSHA WILLS-KARP; H Leighton Grimes; David A Hildeman; Yi Zheng
Distinct roles of Cdc42 in thymopoiesis and effector and memory T cell differentiation.
PloS one 2011;6(3):e18002.
2011: Tesfaye M Baye; Melinda Butsch Kovacic; Jocelyn Biagini Myers; Lisa J Martin; Mark Lindsey; Tia L Patterson; Hua He; Mark B Ericksen; Jayanta Gupta; Anna M Tsoras; Andrew Lindsley; Marc E Rothenberg; MARSHA WILLS-KARP; N Tony Eissa; Larry Borish; Gurjit K Khurana Hershey
Differences in candidate gene association between European ancestry and African American asthmatic children.
PloS one 2011;6(2):e16522.
2011: Umasundari Sivaprasad; David J Askew; Mark B Ericksen; Aaron M Gibson; Matthew T Stier; Eric B Brandt; Stacey A Bass; Michael O Daines; Jamila Chakir; Keith F Stringer; Susan E Wert; Jeffrey A Whitsett; Timothy D Le Cras; MARSHA WILLS-KARP; Gary A Silverman; Gurjit K Khurana Hershey
A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.
The Journal of allergy and clinical immunology 2011;127(1):254-61, 261.e1-6.
2011: Raul Chavez Valdez; Rajni Ahlawat; MARSHA WILLS-KARP; Amy Nathan; Tarrah Ezell; Estelle B Gauda
Correlation between serum caffeine levels and changes in cytokine profile in a cohort of preterm infants.
The Journal of pediatrics 2011;158(1):57-64, 64.e1.
2010: MARSHA WILLS-KARP
Allergen-specific pattern recognition receptor pathways.
Current opinion in immunology 2010;22(6):777-82.
2010: MARSHA WILLS-KARP; Martien Kapsenberg
Allergy and hypersensitivity.
Current opinion in immunology 2010;22(6):775-6.
2010: Xun Zhang; Inken Schmudde; Yves Laumonnier; Manoj K Pandey; Jennifer R Clark; Peter König; Norma P Gerard; Craig Gerard; MARSHA WILLS-KARP; Jörg Köhl
A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(11):6741-52.
2010: Stephane Lajoie; Ian Lewkowich; Yusuke Suzuki; Jennifer R Clark; Alyssa A Sproles; Krista Dienger; Alison L Budelsky; MARSHA WILLS-KARP
Complement-mediated regulation of the IL-17A axis is a central genetic determinant of the severity of experimental allergic asthma.
Nature immunology 2010;11(10):928-35.
2010: Celine S Lages; Ian Lewkowich; Alyssa Sproles; MARSHA WILLS-KARP; Claire Chougnet
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway.
Aging cell 2010;9(5):785-98.
2010: Gang Chen; Huajing Wan; Fengming Luo; Liqian Zhang; Yan Xu; Ian Lewkowich; MARSHA WILLS-KARP; Jeffrey A Whitsett
Foxa2 programs Th2 cell-mediated innate immunity in the developing lung.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(11):6133-41.
2010: Vanessa Saunders; Patrick N Breysse; Jennifer Clark; Alyssa A Sproles; Melissa Davila; MARSHA WILLS-KARP
Particulate matter-induced airway hyperresponsiveness is lymphocyte dependent.
Environmental health perspectives 2010;118(5):640-6.
2010: Fred D Finkelman; Simon P Hogan; Gurjit K Khurana Hershey; Marc E Rothenberg; MARSHA WILLS-KARP
Importance of cytokines in murine allergic airway disease and human asthma.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1663-74.
2010: Kristen Page; John R Ledford; Ping Zhou; Krista Dienger; MARSHA WILLS-KARP
Mucosal sensitization to German cockroach involves protease-activated receptor-2.
Respiratory research 2010;11():62.
2009: Kristen Page; John R Ledford; Ping Zhou; MARSHA WILLS-KARP
A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):3400-8.
2009: YuanYuan Gu; Isaac T W Harley; Lindsay B Henderson; Bruce Aronow; Ilja Vietor; Lukas A Huber; John B Harley; Jeffrey R Kilpatrick; Carl D Langefeld; Adrienne H Williams; Anil G Jegga; Jing Chen; MARSHA WILLS-KARP; S Hasan Arshad; Susan L Ewart; Chloe L Thio; Leah M Flick; Marie-Dominique Filippi; H Leighton Grimes; Mitchell L Drumm; Garry R Cutting; Michael Knowles; Christopher L Karp
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease.
Nature 2009;458(7241):1039-42.
2009: Xun Zhang; Ian Lewkowich; Gabriele Köhl; Jennifer R Clark; MARSHA WILLS-KARP; Jörg Köhl
A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5123-30.
2009: Christina C Lewis; Bruce Aronow; John Hutton; Joanna Santeliz; Krista Dienger; Nancy S Herman; Fred D Finkelman; MARSHA WILLS-KARP
Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung.
The Journal of allergy and clinical immunology 2009;123(4):795-804.e8.
2009: Amy T Nathan; Elizabeth A Peterson; Jamila Chakir; MARSHA WILLS-KARP
Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways.
The Journal of allergy and clinical immunology 2009;123(3):612-8.
2009: Raul Chavez-Valdez; MARSHA WILLS-KARP; Rajni Ahlawat; ELIZABETH CRISTOFALO; Amy Nathan; Estelle B Gauda
Caffeine modulates TNF-alpha production by cord blood monocytes: the role of adenosine receptors.
Pediatric research 2009;65(2):203-8.
2009: Aurelien Trompette; Senad Divanovic; Alberto Visintin; Carine Blanchard; Rashmi S Hegde; Rajat Madan; Peter S Thorne; MARSHA WILLS-KARP; Theresa L Gioannini; Jerry P Weiss; Christopher L Karp
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein.
Nature 2009;457(7229):585-8.
2009: Kathryn A Niese; Ann R Collier; Amanda R Hajek; Stephen D Cederbaum; William E O'Brien; MARSHA WILLS-KARP; Marc E Rothenberg; Nives Zimmermann
Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice.
BMC immunology 2009;10():33.
2008: Weiguo Chen; Yasuhiro Tabata; Aaron M Gibson; Michael O Daines; Manoj R Warrier; MARSHA WILLS-KARP; Gurjit K Khurana Hershey
Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo.
The Journal of allergy and clinical immunology 2008;122(3):625-32.
2008: Kristen Page; Kristin M Lierl; Valerie S Hughes; Ping Zhou; John R Ledford; MARSHA WILLS-KARP
TLR2-mediated activation of neutrophils in response to German cockroach frass.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(9):6317-24.
2008: Fred D Finkelman; MARSHA WILLS-KARP
Usefulness and optimization of mouse models of allergic airway disease.
The Journal of allergy and clinical immunology 2008;121(3):603-6.
2008: MARSHA WILLS-KARP; Fred D Finkelman
Untangling the complex web of IL-4- and IL-13-mediated signaling pathways.
Science signaling 2008;1(51):pe55.
2008: Ian Lewkowich; Stephane Lajoie; Jennifer R Clark; Nancy S Herman; Alyssa A Sproles; MARSHA WILLS-KARP
Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice.
PloS one 2008;3(12):e3879.
2007: Marat Khodoun; Christina C Lewis; Christina Lewis; Jun-Qi Yang; Tatyana Orekov; Crystal Potter; Thomas Wynn; Margaret M Mentink-Kane; Gurjit K Khurana Hershey; MARSHA WILLS-KARP; Fred D Finkelman
Differences in expression, affinity, and function of soluble (s)IL-4Ralpha and sIL-13Ralpha2 suggest opposite effects on allergic responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6429-38.
2007: MARSHA WILLS-KARP
Complement activation pathways: a bridge between innate and adaptive immune responses in asthma.
Proceedings of the American Thoracic Society 2007;4(3):247-51.
2007: Jörg Köhl; MARSHA WILLS-KARP
A dual role for complement in allergic asthma.
Current opinion in pharmacology 2007;7(3):283-9.
2007: Hiam Abdala-Valencia; Julie Earwood; Shelly Bansal; Michael Jansen; George Babcock; Beth A Garvy; MARSHA WILLS-KARP; Joan M Cook-Mills
Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1111-25.
2007: Kristen Page; Kristin M Lierl; Nancy S Herman; MARSHA WILLS-KARP
Differences in susceptibility to German cockroach frass and its associated proteases in induced allergic inflammation in mice.
Respiratory research 2007;8():91.
2007: Jörg Köhl; MARSHA WILLS-KARP
Complement regulates inhalation tolerance at the dendritic cell/T cell interface.
Molecular immunology 2007;44(1-3):44-56.
2006: Ravisankar A Ramadas; Xingnan Li; Dennis M Shubitowski; Sridhar Samineni; MARSHA WILLS-KARP; Susan L Ewart
IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma.
Immunogenetics 2006;58(10):851-5.
2006: X Li; MARSHA WILLS-KARP; Susan L Ewart
Investigating Gata3 as a positional candidate gene for allergic asthma in a murine model.
International journal of immunogenetics 2006;33(5):333-7.
2006: Charles Perkins; MARSHA WILLS-KARP; Fred D Finkelman
IL-4 induces IL-13-independent allergic airway inflammation.
The Journal of allergy and clinical immunology 2006;118(2):410-9.
2006: Faisal Adhami; Guanghong Liao; Yury M Morozov; Aryn Schloemer; Vincent J Schmithorst; John N Lorenz; R Scott Dunn; Charles V Vorhees; MARSHA WILLS-KARP; Jay L Degen; Roger J Davis; Noboru Mizushima; Pasko Rakic; Bernard Dardzinski; Scott K Holland; Frank R Sharp; Chia-Yi Kuan
Cerebral ischemia-hypoxia induces intravascular coagulation and autophagy.
The American journal of pathology 2006;169(2):566-83.
2006: Kathleen C Barnes; Audrey Grant; Peisong Gao; Daniela Baltadjieva; Tiina Berg; Peter Chi; Shu Zhang; April Zambelli-Weiner; Eva Ehrlich; Omeed Zardkoohi; Mary E Brummet; MARIA STOCKTON PORTER; Tonya Watkins; Li Gao; Marquita Gittens; MARSHA WILLS-KARP; Chris Cheadle; Lisa A Beck; Terri H beaty; Kevin G Becker; Joe G. N. Garcia; Rasika A Mathias
Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.
The Journal of allergy and clinical immunology 2006;118(1):70-7.
2006: Jörg Köhl; Ralf Baelder; Ian Lewkowich; Manoj K Pandey; Heiko Hawlisch; Lihua Wang; Jennifer Best; Nancy S Herman; Alyssa A Sproles; Jörg Zwirner; Jeffrey A Whitsett; Craig Gerard; Georgia Sfyroera; John D Lambris; MARSHA WILLS-KARP
A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma.
The Journal of clinical investigation 2006;116(3):783-96.
2006: Maximillian T Follettie; D K Ellis; Debra D Donaldson; Andrew A Hill; Veronica Diesl; C DeClercq; Joseph P Sypek; Andrew J Dorner; MARSHA WILLS-KARP
Gene expression analysis in a murine model of allergic asthma reveals overlapping disease and therapy dependent pathways in the lung.
The pharmacogenomics journal 2006;6(2):141-52.
2006: Cynthia A Molloy; Ardythe L Morrow; Jareen Meinzen-Derr; Kathleen Schleifer; Krista Dienger; Patricia Manning-Courtney; Mekibib Altaye; MARSHA WILLS-KARP
Elevated cytokine levels in children with autism spectrum disorder.
Journal of neuroimmunology 2006;172(1-2):198-205.
2006: Jens Goebel; Kathy Forrest; MARSHA WILLS-KARP; Thomas L Roszman
Tubulin polymerization modulates interleukin-2 receptor signal transduction in human T cells.
Journal of receptor and signal transduction research 2006;26(1-2):87-106.
2006: Judith C Keen; Antonella Cianferoni; Giovanni Florio; Jia Guo; Rongbing Chen; Jesse Roman; MARSHA WILLS-KARP; Vincenzo Casolaro; Steve N Georas
Characterization of a novel PMA-inducible pathway of interleukin-13 gene expression in T cells.
Immunology 2006;117(1):29-37.
2006: Kathleen C Barnes; Audrey V Grant; D Baltadzhieva; Shu Zhang; T Berg; L Shao; April Zambelli-Weiner; W Anderson; A Nelsen; Sreekumar Pillai; David P Yarnall; K Dienger; Roxann G Ingersoll; Alan F Scott; MARGARET D FALLIN; Rasika A Mathias; Terri H beaty; Joe G. N. Garcia; MARSHA WILLS-KARP
Variants in the gene encoding C3 are associated with asthma and related phenotypes among African Caribbean families.
Genes and immunity 2006;7(1):27-35.
2005: Ian Lewkowich; Nancy S Herman; Kathleen W Schleifer; Matthew P Dance; Brian L Chen; Krista M Dienger; Alyssa A Sproles; Jaimin S Shah; Jörg Köhl; Yasmine Belkaid; MARSHA WILLS-KARP
CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function.
The Journal of experimental medicine 2005;202(11):1549-61.
2005: Edith M Hessel; Mabel Chu; Jennifer O Lizcano; Bonnie Chang; Nancy S Herman; Sariah A Kell; MARSHA WILLS-KARP; Robert L Coffman
Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction.
The Journal of experimental medicine 2005;202(11):1563-73.
2005: Jens Goebel; Barbara Logan; Kathy Forrest; Alexandra Mieczkowski; Thomas L Roszman; MARSHA WILLS-KARP
Atorvastatin affects interleukin-2 signaling by altering the lipid raft enrichment of the interleukin-2 receptor beta chain.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2005;53(6):322-8.
2005: MARSHA WILLS-KARP; Joerg Koehl
New insights into the role of the complement pathway in allergy and asthma.
Current allergy and asthma reports 2005;5(5):362-9.
2005: Nives Zimmermann; Matthew P Doepker; David P Witte; Keith F Stringer; Patricia C Fulkerson; Samuel M Pope; Eric B Brandt; Anil Mishra; Nina E King; Nikolaos M Nikolaidis; MARSHA WILLS-KARP; Fred D Finkelman; Marc E Rothenberg
Expression and regulation of small proline-rich protein 2 in allergic inflammation.
American journal of respiratory cell and molecular biology 2005;32(5):428-35.
2005: Fred D Finkelman; Mingyan Yang; Charles Perkins; Kathleen W Schleifer; Alyssa A Sproles; Joanna V Santeliz; Jonathan A Bernstein; Marc E Rothenberg; Suzanne C Morris; MARSHA WILLS-KARP
Suppressive effect of IL-4 on IL-13-induced genes in mouse lung.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4630-8.
2005: Jesus R Guajardo; Kathleen W Schleifer; Michael O Daines; Richard M Ruddy; Bruce Aronow; MARSHA WILLS-KARP; Gurjit K Khurana Hershey
Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma.
The Journal of allergy and clinical immunology 2005;115(2):243-51.
2004: MARSHA WILLS-KARP
Interleukin-13 in asthma pathogenesis.
Immunological reviews 2004;202():175-90.
2004: MARSHA WILLS-KARP; Christopher L Karp
Chitin checking--novel insights into asthma.
The New England journal of medicine 2004;351(14):1455-7.
2004: MARSHA WILLS-KARP; Christopher L Karp
Biomedicine. Eosinophils in asthma: remodeling a tangled tale.
Science (New York, N.Y.) 2004;305(5691):1726-9.
2004: Heiko Hawlisch; MARSHA WILLS-KARP; Christopher L Karp; Jörg Köhl
The anaphylatoxins bridge innate and adaptive immune responses in allergic asthma.
Molecular immunology 2004;41(2-3):123-31.
2004: Kathleen C Barnes; Luis Caraballo; M Muñoz; April Zambelli-Weiner; Eva Ehrlich; M Burki; S Jimenez; Rasika A Mathias; MARIA STOCKTON PORTER; Philipp Deindl; L Mendoza; Gurjit K Khurana Hershey; Renate Nickel; MARSHA WILLS-KARP
A novel promoter polymorphism in the gene encoding complement component 5 receptor 1 on chromosome 19q13.3 is not associated with asthma and atopy in three independent populations.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2004;34(5):736-44.
2004: MARSHA WILLS-KARP; Susan L Ewart
Time to draw breath: asthma-susceptibility genes are identified.
Nature reviews. Genetics 2004;5(5):376-87.
2004: Christopher L Karp; Leah M Flick; Kiwon W Park; Samir Softic; Todd M Greer; Raquel Keledjian; Rong Yang; Jasim Uddin; William B Guggino; Sowsan F Atabani; Yasmine Belkaid; Yan Xu; Jeffrey A Whitsett; Frank J Accurso; MARSHA WILLS-KARP; Nicos A Petasis
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway.
Nature immunology 2004;5(4):388-92.
2004: MARSHA WILLS-KARP
Interleukin-13 in asthma pathogenesis.
Current allergy and asthma reports 2004;4(2):123-31.
2004: MARSHA WILLS-KARP; Dominique Brandt; Ardythe L Morrow
Understanding the origin of asthma and its relationship to breastfeeding.
Advances in experimental medicine and biology 2004;554():171-91.
2003: MARSHA WILLS-KARP; Yasmine Belkaid; Christopher L Karp
I-Tim-izing the pathways of counter-regulation.
Nature immunology 2003;4(11):1050-2.
2003: MARSHA WILLS-KARP; Monica Chiaramonte
Interleukin-13 in asthma.
Current opinion in pulmonary medicine 2003;9(1):21-7.
2002: Dianne M Walters; Patrick N Breysse; Brian Schofield; MARSHA WILLS-KARP
Complement factor 3 mediates particulate matter-induced airway hyperresponsiveness.
American journal of respiratory cell and molecular biology 2002;27(4):413-8.
2002: Fernando P Polack; Michael N Teng; Peter L Collins; Gregory A Prince; Marcus Exner; Heinz Regele; Dario D Lirman; Richard Rabold; S Hoffman; Christopher L Karp; Steven R Kleeberger; MARSHA WILLS-KARP; Ruth A Karron
A role for immune complexes in enhanced respiratory syncytial virus disease.
The Journal of experimental medicine 2002;196(6):859-65.
2002: Joanna V Santeliz; Gary Van Nest; Paula Traquina; Elizabeth Larsen; MARSHA WILLS-KARP
Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma.
The Journal of allergy and clinical immunology 2002;109(3):455-62.
2002: Dennis M Shubitowski; MARSHA WILLS-KARP; Susan L Ewart
The complement factor 5a receptor gene maps to murine chromosome 7.
Cytogenetic and genome research 2002;97(1-2):133-5.
2001: MARSHA WILLS-KARP
Asthma genetics: not for the TIMid?
Nature immunology 2001;2(12):1095-6.
2001: Anne K Vehmas; David R Borchelt; Donald L Price; D McCarthy; MARSHA WILLS-KARP; M J Peper; Gay Rudow; J Luyinbazi; L T Siew; Juan C Troncoso
beta-Amyloid peptide vaccination results in marked changes in serum and brain Abeta levels in APPswe/PS1DeltaE9 mice, as detected by SELDI-TOF-based ProteinChip technology.
DNA and cell biology 2001;20(11):713-21.
2001: Dianne M Walters; Patrick N Breysse; MARSHA WILLS-KARP
Ambient urban Baltimore particulate-induced airway hyperresponsiveness and inflammation in mice.
American journal of respiratory and critical care medicine 2001;164(8 Pt 1):1438-43.
2001: MARSHA WILLS-KARP; Joanna V Santeliz; C L Karp
The germless theory of allergic disease: revisiting the hygiene hypothesis.
Nature reviews. Immunology 2001;1(1):69-75.
2001: Edward S Chen; Brian M Greenlee; MARSHA WILLS-KARP; David R Moller
Attenuation of lung inflammation and fibrosis in interferon-gamma-deficient mice after intratracheal bleomycin.
American journal of respiratory cell and molecular biology 2001;24(5):545-55.
2001: C L Karp; MARSHA WILLS-KARP
Complement and IL-12: yin and yang.
Microbes and infection / Institut Pasteur 2001;3(2):109-19.
2001: J C Keen; L Sholl; MARSHA WILLS-KARP; Steve N Georas
Preferential activation of nuclear factor of activated T cells c correlates with mouse strain susceptibility to allergic responses and interleukin-4 gene expression.
American journal of respiratory cell and molecular biology 2001;24(1):58-65.
2001: MARSHA WILLS-KARP
IL-12/IL-13 axis in allergic asthma.
The Journal of allergy and clinical immunology 2001;107(1):9-18.
2000: Susan L Ewart; Douglas Kuperman; E Schadt; Clarke G Tankersley; Andrew Grupe; Dennis M Shubitowski; Gary Peltz; MARSHA WILLS-KARP
Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice.
American journal of respiratory cell and molecular biology 2000;23(4):537-45.
2000: Christopher L Karp; Andrew Grupe; E Schadt; Susan L Ewart; M Keane-Moore; PJ Cuomo; J Köhl; L Wahl; Douglas Kuperman; Søren Germer; Dee Aud; Gary Peltz; MARSHA WILLS-KARP
Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma.
Nature immunology 2000;1(3):221-6.
2000: MARSHA WILLS-KARP
Murine models of asthma in understanding immune dysregulation in human asthma.
Immunopharmacology 2000;48(3):263-8.
2000: MARSHA WILLS-KARP
Trophic slime, allergic slime.
American journal of respiratory cell and molecular biology 2000;22(6):637-9.
2000: Dianne M Walters; MARSHA WILLS-KARP; Wayne Mitzner
Assessment of cellular profile and lung function with repeated bronchoalveolar lavage in individual mice.
Physiological genomics 2000;2(1):29-36.
2000: MARSHA WILLS-KARP
The gene encoding interleukin-13: a susceptibility locus for asthma and related traits.
Respiratory research 2000;1(1):19-23.
1999: RJ Mayer; MARSHA WILLS-KARP
Recent insights into pathogenesis and control of asthma and atopic diseases.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48(9):469-70.
1999: Peyton A Eggleston; Timothy J Buckley; Patrick N Breysse; MARSHA WILLS-KARP; Steven R Kleeberger; J J Jaakkola
The environment and asthma in U.S. inner cities.
Environmental health perspectives 1999;107 Suppl 3():439-50.
1999: MARSHA WILLS-KARP
Immunologic basis of antigen-induced airway hyperresponsiveness.
Annual review of immunology 1999;17():255-81.
1998: MARSHA WILLS-KARP; J Luyimbazi; X Xu; Brian Schofield; TY Neben; C L Karp; Debra D Donaldson
Interleukin-13: central mediator of allergic asthma.
Science (New York, N.Y.) 1998;282(5397):2258-61.
1998: AM Keane-Myers; M Wysocka; G Trinchieri; MARSHA WILLS-KARP
Resistance to antigen-induced airway hyperresponsiveness requires endogenous production of IL-12.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(2):919-26.
1998: Douglas Kuperman; Brian Schofield; MARSHA WILLS-KARP; M J Grusby
Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production.
The Journal of experimental medicine 1998;187(6):939-48.
1998: MARSHA WILLS-KARP
Interleukin-12 as a target for modulation of the inflammatory response in asthma.
Allergy 1998;53(2):113-9.
1998: AM Keane-Myers; William C Gause; Fred D Finkelman; X D Xhou; MARSHA WILLS-KARP
Development of murine allergic asthma is dependent upon B7-2 costimulation.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):1036-43.
1997: MARSHA WILLS-KARP; Susan L Ewart
The genetics of allergen-induced airway hyperresponsiveness in mice.
American journal of respiratory and critical care medicine 1997;156(4 Pt 2):S89-96.
1997: AM Keane-Myers; William C Gause; Peter Linsley; S J Chen; MARSHA WILLS-KARP
B7-CD28/CTLA-4 costimulatory pathways are required for the development of T helper cell 2-mediated allergic airway responses to inhaled antigens.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2042-9.
1997: S H Gavett; Daniel O'Hearn; C L Karp; E A Patel; Brian Schofield; Fred D Finkelman; MARSHA WILLS-KARP
Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice.
The American journal of physiology 1997;272(2 Pt 1):L253-61.
1997: MARSHA WILLS-KARP
Smooth muscle as a direct or indirect target accounting for bronchopulmonary hyperresponsiveness.
Research in immunology 1997;148(1):59-72.
1996: X M Li; R K Chopra; T Y Chou; Brian Schofield; MARSHA WILLS-KARP; Shau-Ku Huang
Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(8):3216-9.
1996: W Michael Foster; MARSHA WILLS-KARP; Clarke G Tankersley; X Chen; N C Paquette
Bloodborne markers in humans during multiday exposure to ozone.
Journal of applied physiology (Bethesda, Md. : 1985) 1996;81(2):794-800.
1996: Susan L Ewart; S H Gavett; Joseph B Margolick; MARSHA WILLS-KARP
Cyclosporin A attenuates genetic airway hyperresponsiveness in mice but not through inhibition of CD4+ or CD8+ T cells.
American journal of respiratory cell and molecular biology 1996;14(6):627-34.
1996: MARSHA WILLS-KARP; S H Gavett; Brian Schofield; F Finkelman
Role of interleukin-4 in the development of allergic airway inflammation and airway hyperresponsiveness.
Advances in experimental medicine and biology 1996;409():343-7.
1995: S H Gavett; Daniel O'Hearn; X Li; Shau-Ku Huang; F D Finkelman; MARSHA WILLS-KARP
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.
The Journal of experimental medicine 1995;182(5):1527-36.
1995: X Chen; S H Gavett; MARSHA WILLS-KARP
CD4+ T lymphocyte modulation of ozone-induced murine pulmonary inflammation.
American journal of respiratory cell and molecular biology 1995;12(4):396-403.
1994: S H Gavett; X Chen; F Finkelman; MARSHA WILLS-KARP
Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia.
American journal of respiratory cell and molecular biology 1994;10(6):587-93.
1993: S H Gavett; MARSHA WILLS-KARP
Elevated lung G protein levels and muscarinic receptor affinity in a mouse model of airway hyperreactivity.
The American journal of physiology 1993;265(5 Pt 1):L493-500.
1993: MARSHA WILLS-KARP
Age-related changes in pulmonary muscarinic receptor binding properties.
The American journal of physiology 1993;265(2 Pt 1):L103-9.
1993: MARSHA WILLS-KARP; M I Gilmour
Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(6):2729-35.
1993: MARSHA WILLS-KARP; Y Uchida; J Y Lee; J Jinot; A Hirata; Fusao Hirata
Organ culture with proinflammatory cytokines reproduces impairment of the beta-adrenoceptor-mediated relaxation in tracheas of a guinea pig antigen model.
American journal of respiratory cell and molecular biology 1993;8(2):153-9.
1991: Allison Fryer; MARSHA WILLS-KARP
Dysfunction of M2-muscarinic receptors in pulmonary parasympathetic nerves after antigen challenge.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;71(6):2255-61.
1991: MARSHA WILLS-KARP
Effects of age on muscarinic agonist-induced contraction and IP accumulation in airway smooth muscle.
Life sciences 1991;49(14):1039-45.
1990: R A Baumgartner; MARSHA WILLS-KARP; M J Kaufman; M Munakata; Carol A Hirshman
Serotonin induces constriction and relaxation of the guinea pig airway.
The Journal of pharmacology and experimental therapeutics 1990;255(1):165-73.