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Jonathan R. Beckwith

Research Profile

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Escherichia coli

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TOP 3
Hiroshi Kadokura; Jonathan R. Beckwith
Detecting folding intermediates of a protein as it passes through the bacterial translocation channel.
Raul Perez-Jimenez; Jingyuan Li; Pallav Kosuri; Inmaculada Sanchez-Romero; Arun P Wiita; David Rodriguez-Larrea; Ana Chueca; Arne Holmgren; Antonio Miranda-Vizuete; Katja Becker; Seung-Hyun Cho; Jonathan R. Beckwith; Eric Gelhaye; Jean P Jacquot; Eric A Gaucher; Eric Gaucher; Jose M Sanchez-Ruiz; Bruce J Berne; Julio M Fernandez
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy.
Jonathan R. Beckwith
Genetic suppressors and recovery of repressed biochemical memory.

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All Publications

2009: Hiroshi Kadokura; Jonathan R. Beckwith
Detecting folding intermediates of a protein as it passes through the bacterial translocation channel.
Cell 2009;138(6):1164-73.
2009: Raul Perez-Jimenez; Jingyuan Li; Pallav Kosuri; Inmaculada Sanchez-Romero; Arun P Wiita; David Rodriguez-Larrea; Ana Chueca; Arne Holmgren; Antonio Miranda-Vizuete; Katja Becker; Seung-Hyun Cho; Jonathan R. Beckwith; Eric Gelhaye; Jean P Jacquot; Eric A Gaucher; Eric Gaucher; Jose M Sanchez-Ruiz; Bruce J Berne; Julio M Fernandez
Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy.
Nature structural & molecular biology 2009;16(8):890-6.
2009: Jonathan R. Beckwith
Genetic suppressors and recovery of repressed biochemical memory.
The Journal of biological chemistry 2009;284(19):12585-92.
2009: Seung-Hyun Cho; Jonathan R. Beckwith
Two snapshots of electron transport across the membrane: insights into the structure and function of DsbD.
The Journal of biological chemistry 2009;284(17):11416-24.
2009: Mark D Gonzalez; Jonathan R. Beckwith
Divisome under construction: distinct domains of the small membrane protein FtsB are necessary for interaction with multiple cell division proteins.
Journal of bacteriology 2009;191(8):2815-25.
2009: Markus Eser; Lluis Masip; Hiroshi Kadokura; george Georgiou; Jonathan R. Beckwith
Disulfide bond formation by exported glutaredoxin indicates glutathione's presence in the E. coli periplasm.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1572-7.
2008: Yunpeng Zhou; Tomasz Cierpicki; Ricardo H Flores Jimenez; Stephen M Lukasik; Jeffrey F Ellena; David S Cafiso; Hiroshi Kadokura; Jonathan R. Beckwith; John H Bushweller
NMR solution structure of the integral membrane enzyme DsbB: functional insights into DsbB-catalyzed disulfide bond formation.
Molecular cell 2008;31(6):896-908.
2008: Carine Robichon; Glenn F King; Nathan W Goehring; Jonathan R. Beckwith
Artificial septal targeting of Bacillus subtilis cell division proteins in Escherichia coli: an interspecies approach to the study of protein-protein interactions in multiprotein complexes.
Journal of bacteriology 2008;190(18):6048-59.
2008: Rachel J Dutton; Dana Boyd; Mehmet Berkmen; Jonathan R. Beckwith
Bacterial species exhibit diversity in their mechanisms and capacity for protein disulfide bond formation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11933-8.
2008: Melinda J Faulkner; Karthik Veeravalli; stéphanie gon; george Georgiou; Jonathan R. Beckwith
Functional plasticity of a peroxidase allows evolution of diverse disulfide-reducing pathways.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6735-40.
2008: Yuji Yamamoto; Dani Ritz; Anne-Gaëlle Planson; Thomas J Jönsson; Melinda J Faulkner; Dana Boyd; Jonathan R. Beckwith; Leslie B Poole
Mutant AhpC peroxiredoxins suppress thiol-disulfide redox deficiencies and acquire deglutathionylating activity.
Molecular cell 2008;29(1):36-45.
2007: Jonathan R. Beckwith; Corey Morris
Misreading Dr. Venter's genome.
Science (New York, N.Y.) 2007;318(5856):1550.
2007: Jiqing Ye; Seung-Hyun Cho; Jessica Fuselier; Weikai Li; Jonathan R. Beckwith; Tom A Rapoport
Crystal structure of an unusual thioredoxin protein with a zinc finger domain.
The Journal of biological chemistry 2007;282(48):34945-51.
2007: Dirk-Jan Scheffers; Carine Robichon; Gert Jan Haan; Tanneke den Blaauwen; Gregory Koningstein; Edwin van Bloois; Jonathan R. Beckwith; Joen Luirink
Contribution of the FtsQ transmembrane segment to localization to the cell division site.
Journal of bacteriology 2007;189(20):7273-80.
2007: Seung-Hyun Cho; Amir Porat; Jiqing Ye; Jonathan R. Beckwith
Redox-active cysteines of a membrane electron transporter DsbD show dual compartment accessibility.
The EMBO journal 2007;26(15):3509-20.
2007: Jonathan R. Beckwith
What lies beyond uranus? Preconceptions, ignorance, serendipity and suppressors in the search for biology's secrets.
Genetics 2007;176(2):733-40.
2007: Weikai Li; Sol Schulman; Dana Boyd; Karl Erlandson; Jonathan R. Beckwith; Tom A Rapoport
The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal.
Molecular cell 2007;26(4):511-21.
2007: Amir Porat; Christopher Horst Lillig; Catrine Johansson; Aristi Potamitou Fernandes; Lennart Nilsson; Arne Holmgren; Jonathan R. Beckwith
The reducing activity of glutaredoxin 3 toward cytoplasmic substrate proteins is restricted by methionine 43.
Biochemistry 2007;46(11):3366-77.
2007: Nathan W Goehring; Carine Robichon; Jonathan R. Beckwith
Role for the nonessential N terminus of FtsN in divisome assembly.
Journal of bacteriology 2007;189(2):646-9.
2007: Nathan W Goehring; Ivana Petrovska; Dana Boyd; Jonathan R. Beckwith
Mutants, suppressors, and wrinkled colonies: mutant alleles of the cell division gene ftsQ point to functional domains in FtsQ and a role for domain 1C of FtsA in divisome assembly.
Journal of bacteriology 2007;189(2):633-45.
2006: Nathan W Goehring; Mark D Gonzalez; Jonathan R. Beckwith
Premature targeting of cell division proteins to midcell reveals hierarchies of protein interactions involved in divisome assembly.
Molecular microbiology 2006;61(1):33-45.
2006: Seung-Hyun Cho; Jonathan R. Beckwith
Mutations of the membrane-bound disulfide reductase DsbD that block electron transfer steps from cytoplasm to periplasm in Escherichia coli.
Journal of bacteriology 2006;188(14):5066-76.
2006: stéphanie gon; Jonathan R. Beckwith
Ribonucleotide reductases: influence of environment on synthesis and activity.
Antioxidants & redox signaling 2006;8(5-6):773-80.
2006: stéphanie gon; Melinda J Faulkner; Jonathan R. Beckwith
In vivo requirement for glutaredoxins and thioredoxins in the reduction of the ribonucleotide reductases of Escherichia coli.
Antioxidants & redox signaling 2006;8(5-6):735-42.
2006: stéphanie gon; Johanna Eltz Camara; Hege K Klungsøyr; Elliott Crooke; Kirsten Skarstad; Jonathan R. Beckwith
A novel regulatory mechanism couples deoxyribonucleotide synthesis and DNA replication in Escherichia coli.
The EMBO journal 2006;25(5):1137-47.
2006: Laura Segatori; Lori Murphy; Silvia Arredondo; Hiroshi Kadokura; Hiram Gilbert; Jonathan R. Beckwith; george Georgiou
Conserved role of the linker alpha-helix of the bacterial disulfide isomerase DsbC in the avoidance of misoxidation by DsbB.
The Journal of biological chemistry 2006;281(8):4911-9.
2005: Damon Huber; Myoung-Il Cha; Laurent Debarbieux; Anne-Gaëlle Planson; Nelly Cruz; Gary López; María Luisa Tasayco; Alain Chaffotte; Jonathan R. Beckwith
A selection for mutants that interfere with folding of Escherichia coli thioredoxin-1 in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(52):18872-7.
2005: Jonathan R. Beckwith; Franklin Huang
Should we make a fuss? A case for social responsibility in science.
Nature biotechnology 2005;23(12):1479-80.
2005: Nathan W Goehring; Jonathan R. Beckwith
Diverse paths to midcell: assembly of the bacterial cell division machinery.
Current biology : CB 2005;15(13):R514-26.
2005: Carolyn S Sevier; Hiroshi Kadokura; Vincent C Tam; Jonathan R. Beckwith; Deborah Fass; Chris A Kaiser
The prokaryotic enzyme DsbB may share key structural features with eukaryotic disulfide bond forming oxidoreductases.
Protein science : a publication of the Protein Society 2005;14(6):1630-42.
2005: Damon Huber; Dana Boyd; Yu Xia; Michael H Olma; Mark Gerstein; Jonathan R. Beckwith
Use of thioredoxin as a reporter to identify a subset of Escherichia coli signal sequences that promote signal recognition particle-dependent translocation.
Journal of bacteriology 2005;187(9):2983-91.
2005: Mehmet Berkmen; Dana Boyd; Jonathan R. Beckwith
The nonconsecutive disulfide bond of Escherichia coli phytase (AppA) renders it dependent on the protein-disulfide isomerase, DsbC.
The Journal of biological chemistry 2005;280(12):11387-94.
2005: Eran Or; Dana Boyd; stéphanie gon; Jonathan R. Beckwith; Tom A Rapoport
The bacterial ATPase SecA functions as a monomer in protein translocation.
The Journal of biological chemistry 2005;280(10):9097-105.
2005: Hiroshi Kadokura; Lorenzo Nichols; Jonathan R. Beckwith
Mutational alterations of the key cis proline residue that cause accumulation of enzymatic reaction intermediates of DsbA, a member of the thioredoxin superfamily.
Journal of bacteriology 2005;187(4):1519-22.
2005: Nathan W Goehring; Frederico Gueiros-Filho; Jonathan R. Beckwith
Premature targeting of a cell division protein to midcell allows dissection of divisome assembly in Escherichia coli.
Genes & development 2005;19(1):127-37.
2004: Amir Porat; Seung-Hyun Cho; Jonathan R. Beckwith
The unusual transmembrane electron transporter DsbD and its homologues: a bacterial family of disulfide reductases.
Research in microbiology 2004;155(8):617-22.
2004: Nienke Buddelmeijer; Jonathan R. Beckwith
A complex of the Escherichia coli cell division proteins FtsL, FtsB and FtsQ forms independently of its localization to the septal region.
Molecular microbiology 2004;52(5):1315-27.
2004: Ron Ortenberg; stéphanie gon; Amir Porat; Jonathan R. Beckwith
Interactions of glutaredoxins, ribonucleotide reductase, and components of the DNA replication system of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(19):7439-44.
2004: Hiroshi Kadokura; Hongping Tian; Thomas Zander; James C A Bardwell; Jonathan R. Beckwith
Snapshots of DsbA in action: detection of proteins in the process of oxidative folding.
Science (New York, N.Y.) 2004;303(5657):534-7.
2004: Dominique Belin; L-M Guzman; S Bost; M Konakova; Filo Silva; Jonathan R. Beckwith
Functional activity of eukaryotic signal sequences in Escherichia coli: the ovalbumin family of serine protease inhibitors.
Journal of molecular biology 2004;335(2):437-53.
2003: Lauren D Brandon; Nathan W Goehring; Anuradha Janakiraman; Arthur W Yan; Tong Wu; Jonathan R. Beckwith; Marcia B Goldberg
IcsA, a polarly localized autotransporter with an atypical signal peptide, uses the Sec apparatus for secretion, although the Sec apparatus is circumferentially distributed.
Molecular microbiology 2003;50(1):45-60.
2003: Clark F Schierle; Mehmet Berkmen; Damon Huber; Carol Kumamoto; Dana Boyd; Jonathan R. Beckwith
The DsbA signal sequence directs efficient, cotranslational export of passenger proteins to the Escherichia coli periplasm via the signal recognition particle pathway.
Journal of bacteriology 2003;185(19):5706-13.
2003: Federico Katzen; Jonathan R. Beckwith
Role and location of the unusual redox-active cysteines in the hydrophobic domain of the transmembrane electron transporter DsbD.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(18):10471-6.
2003: Ron Ortenberg; Jonathan R. Beckwith
Functions of thiol-disulfide oxidoreductases in E. coli: redox myths, realities, and practicalities.
Antioxidants & redox signaling 2003;5(4):403-11.
2003: Christine M Toutain; David J Clarke; J A Leeds; J Kuhn; Jonathan R. Beckwith; I Barry Holland; Annick Jacq
The transmembrane domain of the DnaJ-like protein DjlA is a dimerisation domain.
Molecular genetics and genomics : MGG 2003;268(6):761-70.
2003: Hiroshi Kadokura; Federico Katzen; Jonathan R. Beckwith
Protein disulfide bond formation in prokaryotes.
Annual review of biochemistry 2003;72():111-35.
2002: Nienke Buddelmeijer; Jonathan R. Beckwith
Assembly of cell division proteins at the E. coli cell center.
Current opinion in microbiology 2002;5(6):553-7.
2002: Peter Haebel; David Goldstone; Federico Katzen; Jonathan R. Beckwith; Peter Metcalf
The disulfide bond isomerase DsbC is activated by an immunoglobulin-fold thiol oxidoreductase: crystal structure of the DsbC-DsbDalpha complex.
The EMBO journal 2002;21(18):4774-84.
2002: Federico Katzen; Meenal Deshmukh; Fevzi Daldal; Jonathan R. Beckwith
Evolutionary domain fusion expanded the substrate specificity of the transmembrane electron transporter DsbD.
The EMBO journal 2002;21(15):3960-9.
2002: Paola Jurado; Daniel Ritz; Jonathan R. Beckwith; Víctor de Lorenzo; Luis A Fernández
Production of functional single-chain Fv antibodies in the cytoplasm of Escherichia coli.
Journal of molecular biology 2002;320(1):1-10.
2002: Hiroshi Kadokura; Jonathan R. Beckwith
Four cysteines of the membrane protein DsbB act in concert to oxidize its substrate DsbA.
The EMBO journal 2002;21(10):2354-63.
2002: Nienke Buddelmeijer; Nicholas Judson; Dana Boyd; John J Mekalanos; Jonathan R. Beckwith
YgbQ, a cell division protein in Escherichia coli and Vibrio cholerae, localizes in codependent fashion with FtsL to the division site.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(9):6316-21.
2002: Joseph C Chen; Michael Minev; Jonathan R. Beckwith
Analysis of ftsQ mutant alleles in Escherichia coli: complementation, septal localization, and recruitment of downstream cell division proteins.
Journal of bacteriology 2002;184(3):695-705.
2002: Daniel Ritz; Jonathan R. Beckwith
Redox state of cytoplasmic thioredoxin.
Methods in enzymology 2002;347():360-70.
2002: Federico Katzen; Jonathan R. Beckwith
Disulfide bond formation in periplasm of Escherichia coli.
Methods in enzymology 2002;348():54-66.
2002: Hongping Tian; Jonathan R. Beckwith
Genetic screen yields mutations in genes encoding all known components of the Escherichia coli signal recognition particle pathway.
Journal of bacteriology 2002;184(1):111-8.
2001: Hiroshi Kadokura; Jonathan R. Beckwith
The expanding world of oxidative protein folding.
Nature cell biology 2001;3(11):E247-9.
2001: JA Leeds; Dana Boyd; D R Huber; G K Sonoda; H T Luu; D M Engelman; Jonathan R. Beckwith
Genetic selection for and molecular dynamic modeling of a protein transmembrane domain multimerization motif from a random Escherichia coli genomic library.
Journal of molecular biology 2001;313(1):181-95.
2001: Daniel Ritz; J Lim; C Michael Reynolds; Leslie B Poole; Jonathan R. Beckwith
Conversion of a peroxiredoxin into a disulfide reductase by a triplet repeat expansion.
Science (New York, N.Y.) 2001;294(5540):158-60.
2001: Joseph C Chen; Jonathan R. Beckwith
FtsQ, FtsL and FtsI require FtsK, but not FtsN, for co-localization with FtsZ during Escherichia coli cell division.
Molecular microbiology 2001;42(2):395-413.
2001: David Goldstone; Peter Haebel; Federico Katzen; Martin W Bader; James C A Bardwell; Jonathan R. Beckwith; Peter Metcalf
DsbC activation by the N-terminal domain of DsbD.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9551-6.
2001: Jonathan R. Beckwith
On the social responsibility of scientists.
Annali dell'Istituto superiore di sanità 2001;37(2):189-94.
2001: Daniel Ritz; Jonathan R. Beckwith
Roles of thiol-redox pathways in bacteria.
Annual review of microbiology 2001;55():21-48.
2000: Federico Katzen; Jonathan R. Beckwith
Transmembrane electron transfer by the membrane protein DsbD occurs via a disulfide bond cascade.
Cell 2000;103(5):769-79.
2000: Hiroshi Kadokura; M Bader; Hongping Tian; James C A Bardwell; Jonathan R. Beckwith
Roles of a conserved arginine residue of DsbB in linking protein disulfide-bond-formation pathway to the respiratory chain of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(20):10884-9.
2000: JS Alper; Jonathan R. Beckwith
On the philosophical analysis of genetic essentialism. Commentary on: "The use of genetic test information in insurance: the argument from indistinguishability reconsidered".
Science and engineering ethics 2000;6(3):311-4.
2000: Hongping Tian; Dana Boyd; Jonathan R. Beckwith
A mutant hunt for defects in membrane protein assembly yields mutations affecting the bacterial signal recognition particle and Sec machinery.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4730-5.
2000: Dana Boyd; DS Weiss; Joseph C Chen; Jonathan R. Beckwith
Towards single-copy gene expression systems making gene cloning physiologically relevant: lambda InCh, a simple Escherichia coli plasmid-chromosome shuttle system.
Journal of bacteriology 2000;182(3):842-7.
2000: Laurent Debarbieux; Jonathan R. Beckwith
On the functional interchangeability, oxidant versus reductant, of members of the thioredoxin superfamily.
Journal of bacteriology 2000;182(3):723-7.
2000: Daniel Ritz; H Patel; B Doan; M Zheng; F Aslund; Gisela Storz; Jonathan R. Beckwith
Thioredoxin 2 is involved in the oxidative stress response in Escherichia coli.
The Journal of biological chemistry 2000;275(4):2505-12.
2000: JA Leeds; Jonathan R. Beckwith
A gene fusion method for assaying interactions of protein transmembrane segments in vivo.
Methods in enzymology 2000;327():165-75.
2000: Jonathan R. Beckwith
The all purpose gene fusion.
Methods in enzymology 2000;326():3-7.
2000: Jean-Marc Ghigo; Jonathan R. Beckwith
Cell division in Escherichia coli: role of FtsL domains in septal localization, function, and oligomerization.
Journal of bacteriology 2000;182(1):116-29.
1999: Paul H Bessette; F Aslund; Jonathan R. Beckwith; george Georgiou
Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13703-8.
1999: E J Stewart; Federico Katzen; Jonathan R. Beckwith
Six conserved cysteines of the membrane protein DsbD are required for the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli.
The EMBO journal 1999;18(21):5963-71.
1999: Laurent Debarbieux; Jonathan R. Beckwith
Electron avenue: pathways of disulfide bond formation and isomerization.
Cell 1999;99(2):117-9.
1999: E Mössner; Martina Huber-Wunderlich; Arne Rietsch; Jonathan R. Beckwith; Rudi Glockshuber; F Aslund
Importance of redox potential for the in vivo function of the cytoplasmic disulfide reductant thioredoxin from Escherichia coli.
The Journal of biological chemistry 1999;274(36):25254-9.
1999: JS Alper; Jonathan R. Beckwith
Racism: a central problem for the Human Genome Diversity Project.
Politics and the life sciences : the journal of the Association for Politics and the Life Sciences 1999;18(2):285-8.
1999: F Aslund; Mei Zheng; Jonathan R. Beckwith; Gisela Storz
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6161-5.
1999: F Aslund; Jonathan R. Beckwith
Bridge over troubled waters: sensing stress by disulfide bond formation.
Cell 1999;96(6):751-3.
1999: F Aslund; Jonathan R. Beckwith
The thioredoxin superfamily: redundancy, specificity, and gray-area genomics.
Journal of bacteriology 1999;181(5):1375-9.
1999: Jean-Marc Ghigo; D S Weiss; J C Chen; J C Yarrow; Jonathan R. Beckwith
Localization of FtsL to the Escherichia coli septal ring.
Molecular microbiology 1999;31(2):725-37.
1999: Joseph C Chen; DS Weiss; J M Ghigo; Jonathan R. Beckwith
Septal localization of FtsQ, an essential cell division protein in Escherichia coli.
Journal of bacteriology 1999;181(2):521-30.
1999: DS Weiss; Joseph C Chen; J M Ghigo; Dana Boyd; Jonathan R. Beckwith
Localization of FtsI (PBP3) to the septal ring requires its membrane anchor, the Z ring, FtsA, FtsQ, and FtsL.
Journal of bacteriology 1999;181(2):508-20.
1998: E J Stewart; F Aslund; Jonathan R. Beckwith
Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxins.
The EMBO journal 1998;17(19):5543-50.
1998: Laurent Debarbieux; Jonathan R. Beckwith
The reductive enzyme thioredoxin 1 acts as an oxidant when it is exported to the Escherichia coli periplasm.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10751-6.
1998: JA Leeds; Jonathan R. Beckwith
Lambda repressor N-terminal DNA-binding domain as an assay for protein transmembrane segment interactions in vivo.
Journal of molecular biology 1998;280(5):799-810.
1998: WA Prinz; D H Boyd; M Ehrmann; Jonathan R. Beckwith
The protein translocation apparatus contributes to determining the topology of an integral membrane protein in Escherichia coli.
The Journal of biological chemistry 1998;273(14):8419-24.
1998: Joseph S Alper; Jonathan R. Beckwith
Distinguishing genetic from nongenetic medical tests: some implications for antidiscrimination legislation.
Science and engineering ethics 1998;4(2):141-50.
1998: Jonathan R. Beckwith; J S Alper
Reconsidering genetic antidiscrimination legislation.
The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics 1998;26(3):205-10, 178.
1998: Arne Rietsch; Jonathan R. Beckwith
The genetics of disulfide bond metabolism.
Annual review of genetics 1998;32():163-84.
1998: D Boyd; C Schierle; Jonathan R. Beckwith
How many membrane proteins are there?
Protein science : a publication of the Protein Society 1998;7(1):201-5.
1997: M Pohlschröder; William A Prinz; E Hartmann; Jonathan R. Beckwith
Protein translocation in the three domains of life: variations on a theme.
Cell 1997;91(5):563-6.
1997: Arne Rietsch; Paul H Bessette; george Georgiou; Jonathan R. Beckwith
Reduction of the periplasmic disulfide bond isomerase, DsbC, occurs by passage of electrons from cytoplasmic thioredoxin.
Journal of bacteriology 1997;179(21):6602-8.
1997: DS Weiss; Kit Pogliano; M Carson; L M Guzman; Claudine Fraipont; Martine Nguyen-Distèche; Richard Losick; Jonathan R. Beckwith
Localization of the Escherichia coli cell division protein Ftsl (PBP3) to the division site and cell pole.
Molecular microbiology 1997;25(4):671-81.
1997: L M Guzman; DS Weiss; Jonathan R. Beckwith
Domain-swapping analysis of FtsI, FtsL, and FtsQ, bitopic membrane proteins essential for cell division in Escherichia coli.
Journal of bacteriology 1997;179(16):5094-103.
1997: WA Prinz; F Aslund; Arne Holmgren; Jonathan R. Beckwith
The role of the thioredoxin and glutaredoxin pathways in reducing protein disulfide bonds in the Escherichia coli cytoplasm.
The Journal of biological chemistry 1997;272(25):15661-7.
1997: Joe Pogliano; AS Lynch; D Belin; Edmund C C Lin; Jonathan R. Beckwith
Regulation of Escherichia coli cell envelope proteins involved in protein folding and degradation by the Cpx two-component system.
Genes & development 1997;11(9):1169-82.
1997: Jonathan R. Beckwith; Lisa N Geller
Commentary on "The social responsibilities of biological scientists" (S.J. Reiser and R.E. Bulger)
Science and engineering ethics 1997;3(2):145-8.
1997: Joe Pogliano; Kit Pogliano; DS Weiss; Richard Losick; Jonathan R. Beckwith
Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(2):559-64.
1996: Arne Rietsch; D Belin; N Martin; Jonathan R. Beckwith
An in vivo pathway for disulfide bond isomerization in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(23):13048-53.
1996: W A Prinz; C Spiess; Michael Ehrmann; C Schierle; Jonathan R. Beckwith
Targeting of signal sequenceless proteins for export in Escherichia coli with altered protein translocase.
The EMBO journal 1996;15(19):5209-17.
1996: M Pohlschröder; C Murphy; Jonathan R. Beckwith
In vivo analyses of interactions between SecE and SecY, core components of the Escherichia coli protein translocation machinery.
The Journal of biological chemistry 1996;271(33):19908-14.
1996: A Allen; B Anderson; L Andrews; Jonathan R. Beckwith; J Bowman; R Cook-Deegan; D Cox; T Duster; R Eisenberg; B Fine; N Holtzman; P King; P Kitcher; J McInerney; Victor A McKusick; J Mulvihill; J Murray; R Murray; T Murray; Dorothy Nelkin; R Rapp; M Saxton; N Wexler
The Bell Curve: statement by the NIH-DOE Joint Working Group on the Ethical, Legal, and Social Implications of Human Genome Research.
American journal of human genetics 1996;59(2):487-8.
1996: G Jander; John E Cronan; Jonathan R. Beckwith
Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion.
Journal of bacteriology 1996;178(11):3049-58.
1996: Lisa N Geller; Joseph S Alper; Paul R Billings; Carol I Barash; Jonathan R. Beckwith; Marvin R Natowicz
Individual, family, and societal dimensions of genetic discrimination: a case study analysis.
Science and engineering ethics 1996;2(1):71-88.
1995: A Economou; J A Pogliano; Jonathan R. Beckwith; D B Oliver; William Wickner
SecA membrane cycling at SecYEG is driven by distinct ATP binding and hydrolysis events and is regulated by SecD and SecF.
Cell 1995;83(7):1171-81.
1995: C Guilhot; G Jander; N L Martin; Jonathan R. Beckwith
Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9895-9.
1995: L M Guzman; D Belin; M J Carson; Jonathan R. Beckwith
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter.
Journal of bacteriology 1995;177(14):4121-30.
1995: A I Derman; Jonathan R. Beckwith
Escherichia coli alkaline phosphatase localized to the cytoplasm slowly acquires enzymatic activity in cells whose growth has been suspended: a caution for gene fusion studies.
Journal of bacteriology 1995;177(13):3764-70.
1995: C K Murphy; E J Stewart; Jonathan R. Beckwith
A double counter-selection system for the study of null alleles of essential genes in Escherichia coli.
Gene 1995;155(1):1-7.
1995: J J Barondess; Jonathan R. Beckwith
bor gene of phage lambda, involved in serum resistance, encodes a widely conserved outer membrane lipoprotein.
Journal of bacteriology 1995;177(5):1247-53.
1995: C Murphy; W Prinz; M Pohlschröder; A Derman; Jonathan R. Beckwith
Essential features of the pathway for protein translocation across the Escherichia coli cytoplasmic membrane.
Cold Spring Harbor symposia on quantitative biology 1995;60():277-83.
1994: G Jander; N L Martin; Jonathan R. Beckwith
Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation.
The EMBO journal 1994;13(21):5121-7.
1994: W A Prinz; Jonathan R. Beckwith
Gene fusion analysis of membrane protein topology: a direct comparison of alkaline phosphatase and beta-lactamase fusions.
Journal of bacteriology 1994;176(20):6410-3.
1994: C K Murphy; Jonathan R. Beckwith
Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(7):2557-61.
1994: Joe Pogliano; Jonathan R. Beckwith
SecD and SecF facilitate protein export in Escherichia coli.
The EMBO journal 1994;13(3):554-61.
1994: Kit Pogliano; Jonathan R. Beckwith
Genetic and molecular characterization of the Escherichia coli secD operon and its products.
Journal of bacteriology 1994;176(3):804-14.
1993: A I Derman; W A Prinz; D Belin; Jonathan R. Beckwith
Mutations that allow disulfide bond formation in the cytoplasm of Escherichia coli.
Science (New York, N.Y.) 1993;262(5140):1744-7.
1993: J S Alper; Jonathan R. Beckwith
Genetic fatalism and social policy: the implications of behavior genetics research.
The Yale journal of biology and medicine 1993;66(6):511-24.
1993: James C A Bardwell; Jonathan R. Beckwith
The bonds that tie: catalyzed disulfide bond formation.
Cell 1993;74(5):769-71.
1993: L N Geller; A H Ahn; Jonathan R. Beckwith; C Barash
Insurance commissioners and genetic discrimination.
American journal of human genetics 1993;52(5):1018.
1993: J L Martin; G Waksman; James C A Bardwell; Jonathan R. Beckwith; John Kuriyan
Crystallization of DsbA, an Escherichia coli protein required for disulphide bond formation in vivo.
Journal of molecular biology 1993;230(3):1097-100.
1993: Kit Pogliano; Jonathan R. Beckwith
The Cs sec mutants of Escherichia coli reflect the cold sensitivity of protein export itself.
Genetics 1993;133(4):763-73.
1993: A I Derman; J W Puziss; P J Bassford; Jonathan R. Beckwith
A signal sequence is not required for protein export in prlA mutants of Escherichia coli.
The EMBO journal 1993;12(3):879-88.
1993: B Traxler; Dana Boyd; Jonathan R. Beckwith
The topological analysis of integral cytoplasmic membrane proteins.
The Journal of membrane biology 1993;132(1):1-11.
1993: James C A Bardwell; J O Lee; G Jander; N Martin; D Belin; Jonathan R. Beckwith
A pathway for disulfide bond formation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(3):1038-42.
1993: Dana Boyd; B Traxler; G Jander; W Prinz; Jonathan R. Beckwith
Gene fusion approaches to membrane protein topology.
Society of General Physiologists series 1993;48():23-37.
1993: Dana Boyd; B Traxler; Jonathan R. Beckwith
Analysis of the topology of a membrane protein by using a minimum number of alkaline phosphatase fusions.
Journal of bacteriology 1993;175(2):553-6.
1992: L M Guzman; J J Barondess; Jonathan R. Beckwith
FtsL, an essential cytoplasmic membrane protein involved in cell division in Escherichia coli.
Journal of bacteriology 1992;174(23):7716-28.
1992: B Traxler; Jonathan R. Beckwith
Assembly of a hetero-oligomeric membrane protein complex.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10852-6.
1992: Paul R Billings; Joseph S Alper; Jonathan R. Beckwith; Carol I Barash; Marvin R Natowicz
Reply to Hook and Lowden: the definition and implications of genetic discrimination.
American journal of human genetics 1992;51(4):903-5.
1992: K Johnson; C K Murphy; Jonathan R. Beckwith
Protein export in Escherichia coli.
Current opinion in biotechnology 1992;3(5):481-5.
1992: P R Billings; Jonathan R. Beckwith; J S Alper
The genetic analysis of human behavior: a new era?
Social science & medicine (1982) 1992;35(3):227-38.
1992: P Billings; Jonathan R. Beckwith
Genetic testing in the workplace: a view from the USA.
Trends in genetics : TIG 1992;8(6):198-202.
1992: B Traxler; C Lee; Dana Boyd; Jonathan R. Beckwith
The dynamics of assembly of a cytoplasmic membrane protein in Escherichia coli.
The Journal of biological chemistry 1992;267(8):5339-45.
1992: P R Billings; M A Kohn; MARGARET DE CUEVAS; Jonathan R. Beckwith; J S Alper; Marvin R Natowicz
Discrimination as a consequence of genetic testing.
American journal of human genetics 1992;50(3):476-82.
1991: A I Derman; Jonathan R. Beckwith
Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in the cytoplasm.
Journal of bacteriology 1991;173(23):7719-22.
1991: K McGovern; Jonathan R. Beckwith
Membrane insertion of the Escherichia coli MalF protein in cells with impaired secretion machinery.
The Journal of biological chemistry 1991;266(31):20870-6.
1991: James C A Bardwell; K McGovern; Jonathan R. Beckwith
Identification of a protein required for disulfide bond formation in vivo.
Cell 1991;67(3):581-9.
1991: K McGovern; Michael Ehrmann; Jonathan R. Beckwith
Decoding signals for membrane protein assembly using alkaline phosphatase fusions.
The EMBO journal 1991;10(10):2773-82.
1991: Michael Ehrmann; Jonathan R. Beckwith
Proper insertion of a complex membrane protein in the absence of its amino-terminal export signal.
The Journal of biological chemistry 1991;266(25):16530-3.
1991: P J Schatz; K L Bieker; Karen M Ottemann; Thomas J Silhavy; Jonathan R. Beckwith
One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery.
The EMBO journal 1991;10(7):1749-57.
1991: P Bassford; Jonathan R. Beckwith; K Ito; C Kumamoto; S Mizushima; D Oliver; Linda L Randall; T Silhavy; Phang-Cheng Tai; B Wickner
The primary pathway of protein export in E. coli.
Cell 1991;65(3):367-8.
1991: M J Carson; J Barondess; Jonathan R. Beckwith
The FtsQ protein of Escherichia coli: membrane topology, abundance, and cell division phenotypes due to overproduction and insertion mutations.
Journal of bacteriology 1991;173(7):2187-95.
1991: Jonathan R. Beckwith
"Sequence-gazing?".
Science (New York, N.Y.) 1991;251(4998):1161-2.
1991: J J Barondess; M Carson; L M Guzman Verduzco; Jonathan R. Beckwith
Alkaline phosphatase fusions in the study of cell division genes.
Research in microbiology 1991;142(2-3):295-9.
1991: Jonathan R. Beckwith
Foreword: the human genome initiative: genetics' lightning rod.
American journal of law & medicine 1991;17(1-2):1-13.
1991: Jonathan R. Beckwith
Strategies for finding mutants.
Methods in enzymology 1991;204():3-18.
1990: T Baba; A Jacq; E Brickman; Jonathan R. Beckwith; T Taura; C Ueguchi; Y Akiyama; K Ito
Characterization of cold-sensitive secY mutants of Escherichia coli.
Journal of bacteriology 1990;172(12):7005-10.
1990: C Gardel; K Johnson; A Jacq; Jonathan R. Beckwith
The secD locus of E. coli codes for two membrane proteins required for protein export.
The EMBO journal 1990;9(12):4205-6.
1990: Michael Ehrmann; Dana Boyd; Jonathan R. Beckwith
Genetic analysis of membrane protein topology by a sandwich gene fusion approach.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7574-8.
1990: C Gardel; K Johnson; A Jacq; Jonathan R. Beckwith
The secD locus of E.coli codes for two membrane proteins required for protein export.
The EMBO journal 1990;9(10):3209-16.
1990: E Signer; Jonathan R. Beckwith
Cloning with phi80lac: the French connection.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(10):503-7.
1990: Dana Boyd; Jonathan R. Beckwith
The role of charged amino acids in the localization of secreted and membrane proteins.
Cell 1990;62(6):1031-3.
1990: J J Barondess; Jonathan R. Beckwith
A bacterial virulence determinant encoded by lysogenic coliphage lambda.
Nature 1990;346(6287):871-4.
1990: Colin Manoil; J J Mekalanos; Jonathan R. Beckwith
Alkaline phosphatase fusions: sensors of subcellular location.
Journal of bacteriology 1990;172(2):515-8.
1990: P J Schatz; Jonathan R. Beckwith
Genetic analysis of protein export in Escherichia coli.
Annual review of genetics 1990;24():215-48.
1989: Dana Boyd; Jonathan R. Beckwith
Positively charged amino acid residues can act as topogenic determinants in membrane proteins.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9446-50.
1989: J L San Millan; Dana Boyd; R Dalbey; W Wickner; Jonathan R. Beckwith
Use of phoA fusions to study the topology of the Escherichia coli inner membrane protein leader peptidase.
Journal of bacteriology 1989;171(10):5536-41.
1989: C Lee; P Li; H Inouye; E R Brickman; Jonathan R. Beckwith
Genetic studies on the inability of beta-galactosidase to be translocated across the Escherichia coli cytoplasmic membrane.
Journal of bacteriology 1989;171(9):4609-16.
1989: P J Schatz; Paul Riggs; A Jacq; Michael Fath; Jonathan R. Beckwith
The secE gene encodes an integral membrane protein required for protein export in Escherichia coli.
Genes & development 1989;3(7):1035-44.
1989: K L Strauch; K Johnson; Jonathan R. Beckwith
Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature.
Journal of bacteriology 1989;171(5):2689-96.
1988: P Li; Jonathan R. Beckwith; H Inouye
Alteration of the amino terminus of the mature sequence of a periplasmic protein can severely affect protein export in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7685-9.
1988: C Manoil; D Boyd; Jonathan R. Beckwith
Molecular genetic analysis of membrane protein topology.
Trends in genetics : TIG 1988;4(8):223-6.
1988: Susan Froshauer; G N Green; Dana Boyd; K McGovern; Jonathan R. Beckwith
Genetic analysis of the membrane insertion and topology of MalF, a cytoplasmic membrane protein of Escherichia coli.
Journal of molecular biology 1988;200(3):501-11.
1988: Paul Riggs; A I Derman; Jonathan R. Beckwith
A mutation affecting the regulation of a secA-lacZ fusion defines a new sec gene.
Genetics 1988;118(4):571-9.
1988: K L Strauch; Jonathan R. Beckwith
An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1576-80.
1987: Dana Boyd; C Manoil; Jonathan R. Beckwith
Determinants of membrane protein topology.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8525-9.
1987: Richard H. Ebright; A Kolb; H Buc; T A Kunkel; J S Krakow; Jonathan R. Beckwith
Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(17):6083-7.
1987: C Gutierrez; J Barondess; C Manoil; Jonathan R. Beckwith
The use of transposon TnphoA to detect genes for cell envelope proteins subject to a common regulatory stimulus. Analysis of osmotically regulated genes in Escherichia coli.
Journal of molecular biology 1987;195(2):289-97.
1987: P L Boquet; C Manoil; Jonathan R. Beckwith
Use of TnphoA to detect genes for exported proteins in Escherichia coli: identification of the plasmid-encoded gene for a periplasmic acid phosphatase.
Journal of bacteriology 1987;169(4):1663-9.
1987: C Gardel; S Benson; J Hunt; Susan Michaelis; Jonathan R. Beckwith
secD, a new gene involved in protein export in Escherichia coli.
Journal of bacteriology 1987;169(3):1286-90.
1986: J Lopilato; S Bortner; Jonathan R. Beckwith
Mutations in a new chromosomal gene of Escherichia coli K-12, pcnB, reduce plasmid copy number of pBR322 and its derivatives.
Molecular & general genetics : MGG 1986;205(2):285-90.
1986: C Manoil; Jonathan R. Beckwith
A genetic approach to analyzing membrane protein topology.
Science (New York, N.Y.) 1986;233(4771):1403-8.
1986: Susan Michaelis; J F Hunt; Jonathan R. Beckwith
Effects of signal sequence mutations on the kinetics of alkaline phosphatase export to the periplasm in Escherichia coli.
Journal of bacteriology 1986;167(1):160-7.
1986: C A Lee; Jonathan R. Beckwith
Suppression of growth and protein secretion defects in Escherichia coli secA mutants by decreasing protein synthesis.
Journal of bacteriology 1986;166(3):878-83.
1986: K L Strauch; C A Kumamoto; Jonathan R. Beckwith
Does secA mediate coupling between secretion and translation in Escherichia coli?
Journal of bacteriology 1986;166(2):505-12.
1986: C Lee; Jonathan R. Beckwith
Cotranslational and posttranslational protein translocation in prokaryotic systems.
Annual review of cell biology 1986;2():315-36.
1986: Jonathan R. Beckwith; S Ferro-Novick
Genetic studies on protein export in bacteria.
Current topics in microbiology and immunology 1986;125():5-27.
1985: T J Silhavy; Jonathan R. Beckwith
Uses of lac fusions for the study of biological problems.
Microbiological reviews 1985;49(4):398-418.
1985: C Manoil; Jonathan R. Beckwith
TnphoA: a transposon probe for protein export signals.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(23):8129-33.
1985: C A Kumamoto; Jonathan R. Beckwith
Evidence for specificity at an early step in protein export in Escherichia coli.
Journal of bacteriology 1985;163(1):267-74.
1985: C A Lee; M J Fournier; Jonathan R. Beckwith
Escherichia coli 6S RNA is not essential for growth or protein secretion.
Journal of bacteriology 1985;161(3):1156-61.
1985: Richard H. Ebright; Jonathan R. Beckwith
The catabolite gene activator protein (CAP) is not required for indole-3-acetic acid to activate transcription of the araBAD operon of Escherichia coli K-12.
Molecular & general genetics : MGG 1985;201(1):51-5.
1984: Richard H. Ebright; Pascale Cossart; B Gicquel-Sanzey; Jonathan R. Beckwith
Molecular basis of DNA sequence recognition by the catabolite gene activator protein: detailed inferences from three mutations that alter DNA sequence specificity.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(23):7274-8.
1984: Richard H. Ebright; Pascale Cossart; B Gicquel-Sanzey; Jonathan R. Beckwith
Mutations that alter the DNA sequence specificity of the catabolite gene activator protein of E. coli.
Nature 1984;311(5983):232-5.
1984: Susan Froshauer; Jonathan R. Beckwith
The nucleotide sequence of the gene for malF protein, an inner membrane component of the maltose transport system of Escherichia coli. Repeated DNA sequences are found in the malE-malF intercistronic region.
The Journal of biological chemistry 1984;259(17):10896-903.
1984: S Ferro-Novick; M Honma; Jonathan R. Beckwith
The product of gene secC is involved in the synthesis of exported proteins in E. coli.
Cell 1984;38(1):211-7.
1984: J E Lopilato; J L Garwin; S D Emr; T J Silhavy; Jonathan R. Beckwith
D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport.
Journal of bacteriology 1984;158(2):665-73.
1984: C A Kumamoto; D B Oliver; Jonathan R. Beckwith
Signal sequence mutations disrupt feedback between secretion of an exported protein and its synthesis in E. coli.
Nature 1984;308(5962):863-4.
1984: E R Brickman; D B Oliver; J L Garwin; C Kumamoto; Jonathan R. Beckwith
The use of extragenic suppressors to define genes involved in protein export in Escherichia coli.
Molecular & general genetics : MGG 1984;196(1):24-7.
1983: Susan Michaelis; L Guarente; Jonathan R. Beckwith
In vitro construction and characterization of phoA-lacZ gene fusions in Escherichia coli.
Journal of bacteriology 1983;154(1):356-65.
1983: C A Kumamoto; Jonathan R. Beckwith
Mutations in a new gene, secB, cause defective protein localization in Escherichia coli.
Journal of bacteriology 1983;154(1):253-60.
1983: Susan Michaelis; H Inouye; D Oliver; Jonathan R. Beckwith
Mutations that alter the signal sequence of alkaline phosphatase in Escherichia coli.
Journal of bacteriology 1983;154(1):366-74.
1983: Jonathan R. Beckwith; T J Silhavy
Genetic analysis of protein export in Escherichia coli.
Methods in enzymology 1983;97():3-11.
1983: T J Silhavy; Jonathan R. Beckwith
Isolation and characterization of mutants of Escherichia coli K12 affected in protein localization.
Methods in enzymology 1983;97():11-40.
1982: D B Oliver; Jonathan R. Beckwith
Regulation of a membrane component required for protein secretion in Escherichia coli.
Cell 1982;30(1):311-9.
1982: D B Oliver; Jonathan R. Beckwith
Identification of a new gene (secA) and gene product involved in the secretion of envelope proteins in Escherichia coli.
Journal of bacteriology 1982;150(2):686-91.
1982: J L Garwin; Jonathan R. Beckwith
Secretion and processing of ribose-binding protein in Escherichia coli.
Journal of bacteriology 1982;149(2):789-92.
1982: H Inouye; W Barnes; Jonathan R. Beckwith
Signal sequence of alkaline phosphatase of Escherichia coli.
Journal of bacteriology 1982;149(2):434-9.
1982: D Oliver; C Kumamoto; M Quinlan; Jonathan R. Beckwith
Pleiotropic mutants affecting the secretory apparatus of Escherichia coli.
Annales de microbiologie 1982;133A(1):105-10.
1982: Susan Michaelis; Jonathan R. Beckwith
Mechanism of incorporation of cell envelope proteins in Escherichia coli.
Annual review of microbiology 1982;36():435-65.
1981: D B Oliver; Jonathan R. Beckwith
E. coli mutant pleiotropically defective in the export of secreted proteins.
Cell 1981;25(3):765-72.
1981: K Ito; Jonathan R. Beckwith
Role of the mature protein sequence of maltose-binding protein in its secretion across the E. coli cytoplasmic membrane.
Cell 1981;25(1):143-50.
1981: K Ito; P J Bassford; Jonathan R. Beckwith
Protein localization in E. coli: is there a common step in the secretion of periplasmic and outer-membrane proteins?
Cell 1981;24(3):707-17.
1981: H Inouye; Susan Michaelis; A Wright; Jonathan R. Beckwith
Cloning and restriction mapping of the alkaline phosphatase structural gene (phoA) of Escherichia coli and generation of deletion mutants in vitro.
Journal of bacteriology 1981;146(2):668-75.
1981: S Brown; E R Brickman; Jonathan R. Beckwith
Blue ghosts: a new method for isolating amber mutants defective in essential genes of Escherichia coli.
Journal of bacteriology 1981;146(1):422-5.
1981: Jonathan R. Beckwith
A genetic approach to characterizing complex promoters in E. coli.
Cell 1981;23(2):307-8.
1981: P J Bassford; S D Emr; T J Silhavy; Jonathan R. Beckwith; H Beduelle; J M Clément; J Hedgpeth; M Hofnung
The genetics of protein secretion in Escherichia coli.
Methods in cell biology 1981;23():27-38.
1981: A Sarthy; Susan Michaelis; Jonathan R. Beckwith
Use of gene fusions to determine the orientation of gene phoA on the Escherichia coli chromosome.
Journal of bacteriology 1981;145(1):293-8.
1981: A Sarthy; Susan Michaelis; Jonathan R. Beckwith
Deletion map of the Escherichia coli structural gene for alkaline phosphatase, phoA.
Journal of bacteriology 1981;145(1):288-92.
1980: Hugues BEDOUELLE; P J Bassford; A V Fowler; I Zabin; Jonathan R. Beckwith; Maurice Hofnung
Mutations which alter the function of the signal sequence of the maltose binding protein of Escherichia coli.
Nature 1980;285(5760):78-81.
1980: C N Chang; H Inouye; P Model; Jonathan R. Beckwith
Processing of alkaline phosphatase precursor to the mature enzyme by an Escherichia coli inner membrane preparation.
Journal of bacteriology 1980;142(2):726-8.
1980: J K Welply; A V Fowler; Jonathan R. Beckwith; I Zabin
Positions of early nonsense and deletion mutations in lacZ.
Journal of bacteriology 1980;142(2):732-4.
1980: A M Wu; A B Chapman; T Platt; L P Guarente; Jonathan R. Beckwith
Deletions of distal sequence after termination of transcription at the end of the tryptophan operon in E. coli.
Cell 1980;19(4):829-36.
1980: Jonathan R. Beckwith
Industrial genetic screening.
Science for the people 1980;12(2):20-1.
1980: H A Shuman; T J Silhavy; Jonathan R. Beckwith
Labeling of proteins with beta-galactosidase by gene fusion. Identification of a cytoplasmic membrane component of the Escherichia coli maltose transport system.
The Journal of biological chemistry 1980;255(1):168-74.
1979: B L Wanner; A Sarthy; Jonathan R. Beckwith
Escherichia coli pleiotropic mutant that reduces amounts of several periplasmic and outer membrane proteins.
Journal of bacteriology 1979;140(1):229-39.
1979: A Sarthy; A Fowler; I Zabin; Jonathan R. Beckwith
Use of gene fusions to determine a partial signal sequence of alkaline phosphatase.
Journal of bacteriology 1979;139(3):932-9.
1979: T J Silhavy; E Brickman; P J Bassford; M J Casadaban; H A Shuman; V Schwartz; L Guarente; M Schwartz; Jonathan R. Beckwith
Structure of the malB region in Escherichia coli K12. II. Genetic map of the malE,F,G operon.
Molecular & general genetics : MGG 1979;174(3):249-59.
1979: P J Bassford; T J Silhavy; Jonathan R. Beckwith
Use of gene fusion to study secretion of maltose-binding protein into Escherichia coli periplasm.
Journal of bacteriology 1979;139(1):19-31.
1979: E Brickman; T J Silhavy; P J Bassford; H A Shuman; Jonathan R. Beckwith
Sites within gene lacZ of Escherichia coli for formation of active hybrid beta-galactosidase molecules.
Journal of bacteriology 1979;139(1):13-8.
1979: M L Berman; Jonathan R. Beckwith
Use of gene fusions to isolate promoter mutants in the transfer RNA gene tyrT of Escherichia coli.
Journal of molecular biology 1979;130(3):303-15.
1979: M L Berman; Jonathan R. Beckwith
Fusions of the lac operon to the transfer RNA gene tyrT of Escherichia coli.
Journal of molecular biology 1979;130(3):285-301.
1979: P Bassford; Jonathan R. Beckwith
Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm.
Nature 1979;277(5697):538-41.
1979: H A Shuman; Jonathan R. Beckwith
Escherichia coli K-12 mutants that allow transport of maltose via the beta-galactoside transport system.
Journal of bacteriology 1979;137(1):365-73.
1979: K Bergman; Jonathan R. Beckwith
Human genetic engineering: a social and political perspective.
Biochemical Society symposium 1979;44():133-40.
1978: S Schneider; E Loechler; J King; Jonathan R. Beckwith
Science for the people.
Nature 1978;274(5673):732.
1978: I Zabin; A V Fowler; Jonathan R. Beckwith
Position of the mutation in beta-galactosidase ochre mutant U118.
Journal of bacteriology 1978;133(1):437-8.
1978: L P Guarente; Jonathan R. Beckwith
Mutant RNA polymerase of Escherichia coli terminates transcription in strains making defective rho factor.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(1):294-7.
1977: T J Silhavy; H A Shuman; Jonathan R. Beckwith; M Schwartz
Use of gene fusions to study outer membrane protein localization in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(12):5411-5.
1977: L P Guarente; D H Mitchell; Jonathan R. Beckwith
Transcription termination at the end of the tryptophan operon of Escherichia coli.
Journal of molecular biology 1977;112(3):423-36.
1977: Jonathan R. Beckwith
Recombinant DNA: does the fault lie within our genes?
Science for the people 1977;9(3):14-7.
1977: H Inouye; Jonathan R. Beckwith
Synthesis and processing of an Escherichia coli alkaline phosphatase precursor in vitro.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(4):1440-4.
1977: H Inouye; C Pratt; Jonathan R. Beckwith; A Torriani
Alkaline phosphatase synthesis in a cell-free system using DNA and RNA templates.
Journal of molecular biology 1977;110(1):75-87.
1976: Jonathan R. Beckwith; Larry Miller
The XYY male: the making of a myth.
Harvard magazine 1976;79(2):30-3.
1976: T J Silhavy; M J Casadaban; H A Shuman; Jonathan R. Beckwith
Conversion of beta-galactosidase to a membrane-bound state by gene fusion.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(10):3423-7.
1976: D H Mitchell; W S Reznikoff; Jonathan R. Beckwith
Genetic fusions that help define a transcription termination region in Escherichia coli.
Journal of molecular biology 1976;101(4):441-57.
1976: Jonathan R. Beckwith
Social and political uses of genetics in the United States: past and present.
Annals of the New York Academy of Sciences 1976;265():46-58.
1975: R Pyeritz; Jonathan R. Beckwith; L Miller
Letter: XYY disclosure condemned.
The New England journal of medicine 1975;293(10):508.
1975: E Brickman; Jonathan R. Beckwith
Analysis of the regulation of Escherichia coli alkaline phosphatase synthesis using deletions and phi80 transducing phages.
Journal of molecular biology 1975;96(2):307-16.
1975: D H Mitchell; W S Reznikoff; Jonathan R. Beckwith
Genetic fusions defining trp and lac operon regulatory elements.
Journal of molecular biology 1975;93(3):331-50.
1975: D Sabourin; Jonathan R. Beckwith
Deletion of the Escherichia coli crp gene.
Journal of bacteriology 1975;122(1):338-40.
1975: Jonathan R. Beckwith
Harvard XYY study.
Science (New York, N.Y.) 1975;187(4174):298-9.
1974: Jonathan R. Beckwith; Jonathan King
The XYY syndrome: a dangerous myth.
New scientist (1971) 1974;64(923):474-6.
1974: Frederick Ausubel; Jonathan R. Beckwith; Kaaren Janssen
The politics of genetic engineering: who decides who's defective?
Psychology today 1974;8(1):30+.
1974: Jonathan R. Beckwith; P Rossow
Analysis of genetic regulatory mechanisms.
Annual review of genetics 1974;8():1-13.
1973: E Brickman; L Soll; Jonathan R. Beckwith
Genetic characterization of mutations which affect catabolite-sensitive operons in Escherichia coli, including deletions of the gene for adenyl cyclase.
Journal of bacteriology 1973;116(2):582-7.
1973: R Arditti; T Grodzicker; Jonathan R. Beckwith
Cyclic adenosine monophosphate-independent mutants of the lactose operon of Escherichia coli.
Journal of bacteriology 1973;114(2):652-5.
1972: Jonathan R. Beckwith; T Grodzicker; R Arditti
Evidence for two sites in the lac promoter region.
Journal of molecular biology 1972;69(1):155-60.
1972: Jonathan R. Beckwith
Science for the people.
Annals of the New York Academy of Sciences 1972;196(4):236-40.
1971: K Ippen; J A Shapiro; Jonathan R. Beckwith
Transposition of the lac region to the gal region of the Escherichia coli chromosome: isolation of lambda-lac transducing bacteriophages.
Journal of bacteriology 1971;108(1):5-9.
1971: L Eron; D Morse; W Reznikoff; Jonathan R. Beckwith
Fusions of the lac and trp regions of escherichia coli: covalently fused messenger RNA.
Journal of molecular biology 1971;60(1):203-9.
1971: L Eron; R Arditti; G Zubay; S Connaway; Jonathan R. Beckwith
An adenosine 3':5'-cyclic monophosphate-binding protein that acts on the transcription process.
Proceedings of the National Academy of Sciences of the United States of America 1971;68(1):215-8.
1970: J H Miller; W S Reznikoff; A E Silverstone; K Ippen; E R Signer; Jonathan R. Beckwith
Fusions of the lac and trp Regions of the Escherichia coli Chromosome.
Journal of bacteriology 1970;104(3):1273-9.
1970: Jonathan R. Beckwith
Gene expression in bacteria and some concerns about the misuse of science.
Bacteriological reviews 1970;34(3):222-7.
1970: G Zubay; D Schwartz; Jonathan R. Beckwith
Mechanism of activation of catabolite-sensitive genes: a positive control system.
Proceedings of the National Academy of Sciences of the United States of America 1970;66(1):104-10.
1969: J Shapiro; L Machattie; L Eron; G Ihler; K Ippen; Jonathan R. Beckwith
Isolation of pure lac operon DNA.
Nature 1969;224(5221):768-74.
1969: Susan Gottesman; Jonathan R. Beckwith
Directed transposition of the arabinose operon: a technique for the isolation of specialized transducing bacteriophages for any Escherichia coli gene.
Journal of molecular biology 1969;44(1):117-27.
1969: W S Reznikoff; Jonathan R. Beckwith
Genetic evidence that the operator locus is distinct from the the z gene in the lac operon of Escherichia coli.
Journal of molecular biology 1969;43(1):215-8.
1969: W S Reznikoff; J H Miller; J G Scaife; Jonathan R. Beckwith
A mechanism for repressor action.
Journal of molecular biology 1969;43(1):201-13.
1969: A E Silverstone; B Magasanik; W S Reznikoff; J H Miller; Jonathan R. Beckwith
Catabolite sensitive site of the lac operon.
Nature 1969;221(5185):1012-4.
1969: D O Schwartz; Jonathan R. Beckwith
Mutagens which cause deletions in Escherichia coli.
Genetics 1969;61(2):371-6.
1968: J H Miller; Jonathan R. Beckwith; B Muller-Hill
Direction of transcription of a regulatory gene in E. coli.
Nature 1968;220(5174):1287-90.
1968: R R Arditti; J G Scaife; Jonathan R. Beckwith
The nature of mutants in the lac promoter region.
Journal of molecular biology 1968;38(3):421-6.
1968: J H Miller; K Ippen; J G Scaife; Jonathan R. Beckwith
The promoter-operator region of the lac operon of Escherichia coli.
Journal of molecular biology 1968;38(3):413-20.
1968: B M Ohlsson; P F Strigini; Jonathan R. Beckwith
Allelic amber and ochre suppressors.
Journal of molecular biology 1968;36(2):209-18.
1968: K Ippen; J H Miller; J Scaife; Jonathan R. Beckwith
New controlling element in the Lac operon of E. coli.
Nature 1968;217(5131):825-7.
1967: Jonathan R. Beckwith
Regulation of the lac operon. Recent studies on the regulation of lactose metabolism in Escherichia coli support the operon model.
Science (New York, N.Y.) 1967;156(3775):597-604.
1966: C F Fox; Jonathan R. Beckwith; W Epstein; E R Signer
Transposition of the lac region of Escherichia coli. II. On the role of thiogalactoside transacetylase in lactose metabolism.
Journal of molecular biology 1966;19(2):576-9.
1966: Jonathan R. Beckwith; E R Signer
Transposition of the lac region of Escherichia coli. I. Inversion of the lac operon and transduction of lac by phi80.
Journal of molecular biology 1966;19(2):254-65.
1966: L Gorini; Jonathan R. Beckwith
Suppression.
Annual review of microbiology 1966;20():401-22.
1966: J Scaife; Jonathan R. Beckwith
Mutational alteration of the maximal level of Lac operon expression.
Cold Spring Harbor symposia on quantitative biology 1966;31():403-8.
1966: Jonathan R. Beckwith; E R Signer; W Epstein
Transposition of the Lac region of E. coli.
Cold Spring Harbor symposia on quantitative biology 1966;31():393-401.
1965: W A Newton; Jonathan R. Beckwith; D Zipser; Sydney Brenner
Nonsense mutants and polarity in the lac operon of Escherichia coli.
Journal of molecular biology 1965;14(1):290-6.
1965: E R Signer; Jonathan R. Beckwith; Sydney Brenner
Mapping of suppressor loci in Escherichia coli.
Journal of molecular biology 1965;14(1):153-66.
1964: A L TAYLOR; Jonathan R. Beckwith; A B PARDEE; R AUSTRIAN; F JACOB
THE CHROMOSOMAL LOCATION OF THE STRUCTURAL GENE FOR OROTIDYLIC ACID PYROPHOSPHORYLASE IN ESCHERICHIA COLI.
Journal of molecular biology 1964;8():771.
1964: Jonathan R. Beckwith
A DELETION ANALYSIS OF THE LAC OPERATOR REGION IN ESCHERICHIA COLI.
Journal of molecular biology 1964;8():427-30.
1963: Jonathan R. Beckwith
RESTORATION OF OPERON ACTIVITY BY SUPPRESSORS.
Biochimica et biophysica acta 1963;76():162-4.
1963: Jonathan R. Beckwith; Lowell P Hager
BIOLOGICAL CHLORINATION. VIII. LATE INTERMEDIATES IN THE BIOSYNTHESIS OF CALDARIOMYCIN.
The Journal of biological chemistry 1963;238():3091-4.
1963: Jonathan R. Beckwith; R CLARK; Lowell P Hager
BIOLOGICAL CHLORINATION. VII. STUDIES ON THE BIOSYNTHESIS OF CALDARIOMYCIN.
The Journal of biological chemistry 1963;238():3086-90.
1962: Jonathan R. Beckwith; A B PARDEE; R AUSTRIAN; F JACOB
Coordination of the synthesis of the enzymes in the pyrimidine pathway of E. coli.
Journal of molecular biology 1962;5():618-34.
1962: A B PARDEE; Jonathan R. Beckwith
Genetic determination of constitutive enzyme levels.
Biochimica et biophysica acta 1962;60():452-4.
1959: P D SHAW; Jonathan R. Beckwith; Lowell P Hager
Biological chlorination. II. The biosynthesis of 5-chlorolevulinic acid.
The Journal of biological chemistry 1959;234():2560-4.