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Fergus J. Couch

Research Profile

Disorders

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Concepts & Ideas

Anatomy

Chromosomes, Human, Pair 17

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TOP 3
Sutapa Sinha; Veena Somasundaram; Resham Bhattacharya; Ying Cao; Fergus J. Couch; Shamit Dutta; Ahmed Elkhanany; Seethalakshmi Iyer; Gourish Mondal; Debabrata Mukhopadhyay; Krishnendu Pal; Viji Shridhar; Priya Srinivas
Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo.
Gourish Mondal; Vernon S Pankratz; Matthew Rowley; Jianmin Wu; Lucia Guidugli; Fergus J. Couch
BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis.
John J Heine; Marilyn J Morton; Janet E Olson; V Shane Pankratz; Beth A Schueler; Christopher G Scott; Thomas A Sellers; Daniel J Serie; Kathleen R Brandt; Fergus J. Couch; Fang-Fang Wu; Celine M Vachon
A novel automated mammographic density measure and breast cancer risk.

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All Publications

2013: Sutapa Sinha; Veena Somasundaram; Resham Bhattacharya; Ying Cao; Fergus J. Couch; Shamit Dutta; Ahmed Elkhanany; Seethalakshmi Iyer; Gourish Mondal; Debabrata Mukhopadhyay; Krishnendu Pal; Viji Shridhar; Priya Srinivas
Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo.
International journal of cancer. Journal international du cancer 2013;132(5):1201-12.
2012: Gourish Mondal; Vernon S Pankratz; Matthew Rowley; Jianmin Wu; Lucia Guidugli; Fergus J. Couch
BRCA2 localization to the midbody by filamin A regulates cep55 signaling and completion of cytokinesis.
Developmental cell 2012;23(1):137-52.
2012: John J Heine; Marilyn J Morton; Janet E Olson; V Shane Pankratz; Beth A Schueler; Christopher G Scott; Thomas A Sellers; Daniel J Serie; Kathleen R Brandt; Fergus J. Couch; Fang-Fang Wu; Celine M Vachon
A novel automated mammographic density measure and breast cancer risk.
Journal of the National Cancer Institute 2012;104(13):1028-37.
2012: Amanda B Spurdle; Dominique Stoppa-Lyonnet; Sean V Tavtigian; Barbara Wappenschmidt; Fergus J. Couch; Andrew Devereau; David E Goldgar; Sue Healey; Frans B L Hogervorst; Alvaro N A Monteiro; Katherine L Nathanson; Paolo Radice
ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes.
Human mutation 2012;33(1):2-7.
2011: Sutapa Sinha; Fergus J. Couch; Shamit K Dutta; Da Woon Han; Eun Ju Hwang; Seethalakshmi Iyer; S Ananth Karumanchi; Keun Il Kim; Gourish Mondal; Debabrata Mukhopadhyay
Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.
Journal of cell science 2011;124(Pt 13):2132-42.
2011: Phillip J Whiley; Lucia Guidugli; Logan C Walker; Sue Healey; Bryony A Thompson; Sunil R Lakhani; Leonard M Da Silva; Sean V Tavtigian; David E Goldgar; Melissa A Brown; Fergus J. Couch; Amanda B Spurdle
Splicing and multifactorial analysis of intronic BRCA1 and BRCA2 sequence variants identifies clinically significant splicing aberrations up to 12 nucleotides from the intron/exon boundary.
Human mutation 2011;32(6):678-87.
2011: Matthew Rowley; Akihiro Ohashi; Gourish Mondal; Lisa D. Mills; Lin Yang; Lizhi Zhang; Rhianna Sundsbak; Virginia Shapiro; Michael H Muders; Thomas Smyrk; Fergus J. Couch
Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice.
Gastroenterology 2011;140(4):1303-1313.e1-3.
2011: Janet E Olson; Xianshu Wang; V Shane Pankratz; Zachary S Fredericksen; Celine M Vachon; Robert A Vierkant; James Cerhan; Fergus J. Couch
Centrosome-related genes, genetic variation, and risk of breast cancer.
Breast cancer research and treatment 2011;125(1):221-8.
2010: Susan M Domchek; Tara Friebel; Judy E Garber; Claudine Isaacs; Ellen Matloff; Rosalind Eeles; D Gareth Evans; Wendy Rubinstein; Christian F Singer; Stephen Rubin; Henry T Lynch; Mary B Daly; Jeffrey N Weitzel; Patricia Anne Ganz; Gabriella Pichert; Olufunmilayo I Olopade; Gail Tomlinson; Nadine Tung; Joanne L Blum; Fergus J. Couch; Timothy R Rebbeck
Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers.
Breast cancer research and treatment 2010;124(1):195-203.
2010: Nic Waddell; Jeremy Arnold; Sibylle Cocciardi; Leonard da Silva; Anna Marsh; Joan Riley; Cameron N Johnstone; Mohammed Orloff; Guillaume Assie; Charis Eng; Lynne Reid; Patricia Keith; Max Yan; Stephen Fox; Peter Devilee; Andrew K Godwin; Frans B L Hogervorst; Fergus J. Couch; Sean M Grimmond; James M Flanagan; Kumkum Khanna; Peter T Simpson; Sunil R Lakhani; Georgia Chenevix-Trench
Subtypes of familial breast tumours revealed by expression and copy number profiling.
Breast cancer research and treatment 2010;123(3):661-77.
2010: Susan M Domchek; Tara Friebel; Christian F Singer; D Gareth Evans; Henry T Lynch; Claudine Isaacs; Judy E Garber; Susan L Neuhausen; Ellen Matloff; Rosalind Eeles; Gabriella Pichert; Laura Van t'veer; Nadine Tung; Jeffrey N Weitzel; Fergus J. Couch; Wendy S Rubinstein; Patricia Anne Ganz; Mary B Daly; Olufunmilayo I Olopade; Gail Tomlinson; Joellen Schildkraut; Joanne L Blum; Timothy R Rebbeck
Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality.
JAMA : the journal of the American Medical Association 2010;304(9):967-75.
2010: Logan C Walker; Phillip J Whiley; Fergus J. Couch; Daniel J Farrugia; Sue Healey; Diana M Eccles; Feng Lin; Samantha A Butler; Sheila A Goff; Bryony A Thompson; Sunil R Lakhani; Leonard M Da Silva; Sean V Tavtigian; David E Goldgar; Melissa A Brown; Amanda B Spurdle
Detection of splicing aberrations caused by BRCA1 and BRCA2 sequence variants encoding missense substitutions: implications for prediction of pathogenicity.
Human mutation 2010;31(6):E1484-505.
2010: Fergus J. Couch; Xianshu Wang; William R Bamlet; Mariza de Andrade; Gloria M Petersen; Robert R McWilliams
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010;19(1):251-7.
2010: Xianshu Wang; Zachary S Fredericksen; Robert A Vierkant; Matthew L Kosel; V Shane Pankratz; James R Cerhan; Christina Justenhoven; Hiltrud Brauch; Janet E Olson; Fergus J. Couch
Association of genetic variation in mitotic kinases with breast cancer risk.
Breast cancer research and treatment 2010;119(2):453-62.
2010: Janet E Olson; Xianshu Wang; Ellen L Goode; V Shane Pankratz; Zachary S Fredericksen; Robert A Vierkant; P D P Pharoah; James Cerhan; Fergus J. Couch
Variation in genes required for normal mitosis and risk of breast cancer.
Breast cancer research and treatment 2010;119(2):423-30.
2009: Fergus J. Couch; Xianshu Wang; Robert R McWilliams; William R Bamlet; Mariza de Andrade; Gloria M Petersen
Association of breast cancer susceptibility variants with risk of pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):3044-8.
2009: Julie M Cunningham; Robert A Vierkant; Thomas A Sellers; C Phelan; D N Rider; Mark Liebow; Joellen M Schildkraut; Andrew Berchuck; Fergus J. Couch; Xianshu Wang; Brooke L Fridley; A Gentry-Maharaj; Usha Menon; Estrid Hogdall; Susanne Krüger Kjaer; A Whittemore; Richard A DiCioccio; H Song; Simon A Gayther; S J Ramus; P D P Pharaoh; Ellen L Goode
Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis.
British journal of cancer 2009;101(8):1461-8.
2009: Robert R McWilliams; William R Bamlet; Mariza de Andrade; David N Rider; Fergus J. Couch; Julie M Cunningham; Martha E Matsumoto; Kari G Rabe; Traci J Hammer; Gloria M Petersen
Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(9):2549-52.
2009: Rajini Katipamula; Amy C Degnim; Tanya L Hoskin; Judy C Boughey; Charles L Loprinzi; Clive S Grant; Kathleen R Brandt; Sandhya Pruthi; Christopher G Chute; Janet E Olson; Fergus J. Couch; James N Ingle; Matthew P Goetz
Trends in mastectomy rates at the Mayo Clinic Rochester: effect of surgical year and preoperative magnetic resonance imaging.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(25):4082-8.
2009: Sharon E Johnatty; Fergus J. Couch; Zachary Fredericksen; Robert Tarrell; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Daphne Gschwantler-Kaulich; Christian F Singer; Christine Fuerhauser; Anneliese Fink-Retter; Susan M Domchek; Katherine L Nathanson; Vernon S Pankratz; Noralane Lindor; Andrew K Godwin; Maria A Caligo; John Hopper; Melissa C Southey; Graham G Giles; Christina Justenhoven; Hiltrud Brauch; Ute Hamann; Yon-Dschun Ko; Tuomas Heikkinen; Kirsimari Aaltonen; Kristiina Aittomäki; Carl Blomqvist; Heli Nevanlinna; Per Hall; Kamila Czene; Jianjun Liu; Susan Peock; Margaret Cook; Radka Platte; D Gareth Evans; Fiona Lalloo; Rosalind Eeles; Gabriella Pichert; Diana Eccles; Rosemarie Davidson; Trevor Cole; Jackie Cook; Fiona Douglas; Carol Chu; Shirley Hodgson; Joan Paterson; Frans B L Hogervorst; Matti A Rookus; Caroline Seynaeve; Juul Wijnen; Maaike Vreeswijk; Marjolijn Ligtenberg; Rob B van der Luijt; Theo A M van Os; Hans J P Gille; Marinus J Blok; Claudine Issacs; Manjeet K Humphreys; Lesley McGuffog; Sue Healey; Olga Sinilnikova; Antonis C Antoniou; Douglas F Easton; Georgia Chenevix-Trench
No evidence that GATA3 rs570613 SNP modifies breast cancer risk.
Breast cancer research and treatment 2009;117(2):371-9.
2009: Wataru Sakai; Elizabeth M Swisher; Céline Jacquemont; Kurapaty Venkatapoorna Chandramohan; Fergus J. Couch; Simon P Langdon; Kaitlyn Wurz; Jake Higgins; Villegas Villarreal Elba Crsitina; Toshiyasu Taniguchi
Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.
Cancer research 2009;69(16):6381-6.
2009: Timothy R Rebbeck; Nandita Mitra; Susan M Domchek; Fei Wan; Shaokun Chuai; Tara Friebel; Saarene Panossian; Amanda Spurdle; Georgia Chenevix-Trench; Christian F Singer; Georg Pfeiler; Susan L Neuhausen; Henry T Lynch; Judy E Garber; Jeffrey N Weitzel; Claudine Isaacs; Fergus J. Couch; Steven A Narod; Wendy S Rubinstein; Gail Tomlinson; Patricia Anne Ganz; Olufunmilayo I Olopade; Nadine Tung; Joanne L Blum; Roger A. Greenberg; Katherine L Nathanson; Mary B Daly
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
Cancer research 2009;69(14):5801-10.
2009: Roger L Milne; Javier Benítez; Heli Nevanlinna; Tuomas Heikkinen; Kristiina Aittomäki; Carl Blomqvist; José Ignacio Arias; M Pilar Zamora; Barbara Burwinkel; Claus R Bartram; Alfons Meindl; Rita K Schmutzler; Angela Cox; Ian Brock; Graeme Elliott; Malcolm W R Reed; Melissa C Southey; Letitia Smith; Amanda B Spurdle; John L Hopper; Fergus J. Couch; Janet E Olson; Xianshu Wang; Zachary Fredericksen; Peter Schürmann; Michael Bremer; Peter Hillemanns; Thilo Dörk; Peter Devilee; Christie J van Asperen; Rob A E M Tollenaar; Caroline Seynaeve; Per Hall; Kamila Czene; Jianjun Liu; Yuqing Li; Shahana Ahmed; Alison M Dunning; Melanie Maranian; Paul D P Pharoah; Georgia Chenevix-Trench; Jonathan Beesley; Natalia V Bogdanova; Natalia N Antonenkova; Iosif V Zalutsky; Hoda Anton-Culver; Argyrios Ziogas; Hiltrud Brauch; Christina Justenhoven; Yon-Dschun Ko; Susanne Haas; Peter A Fasching; Reiner Strick; Arif B Ekici; Matthias W Beckmann; Graham G Giles; Gianluca Severi; Laura Baglietto; Dallas R English; Olivia Fletcher; Nichola Johnson; Isabel dos Santos Silva; Julian Peto; Clare Turnbull; Sarah Hines; Anthony Renwick; Nazneen Rahman; Børge G Nordestgaard; Stig E Bojesen; Henrik Flyger; Daehee Kang; Keun-Young Yoo; Dong-Young Noh; Arto Mannermaa; Vesa Kataja; Veli-Matti Kosma; Montserrat García-Closas; STEPHEN CHANOCK; Jolanta Lissowska; Louise A Brinton; Jenny Chang-Claude; Shan Wang-Gohrke; Chen-Yang Shen; Hui-Chun Wang; Jyh-Cherng Yu; Sou-Tong Chen; Marina Bermisheva; Tatjana Nikolaeva; Elza Khusnutdinova; Manjeet K Humphreys; Jonathan Morrison; Radka Platte; Douglas F Easton
Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.
Journal of the National Cancer Institute 2009;101(14):1012-8.
2009: Xianglin Wu; Gourish Mondal; Xianshu Wang; Jianmin Wu; Lin Yang; V Shane Pankratz; Matthew Rowley; Fergus J. Couch
Microcephalin regulates BRCA2 and Rad51-associated DNA double-strand break repair.
Cancer research 2009;69(13):5531-6.
2009: Linda E Kelemen; Xianshu Wang; Zachary S Fredericksen; V Shane Pankratz; Paul D P Pharoah; Shahana Ahmed; Alison M Dunning; Douglas F Easton; Robert A Vierkant; James R Cerhan; Ellen L Goode; Janet E Olson; Fergus J. Couch
Genetic variation in the chromosome 17q23 amplicon and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(6):1864-8.
2009: Mia M. Gaudet; Roger L Milne; Angela Cox; Nicola J Camp; Ellen L Goode; Manjeet K Humphreys; Alison M Dunning; Jonathan Morrison; Graham G Giles; Gianluca Severi; Laura Baglietto; Dallas R English; Fergus J. Couch; Janet E Olson; Xianshu Wang; Jenny Chang-Claude; Dieter Flesch-Janys; Sascha Abbas; Ramona Salazar; Arto Mannermaa; Vesa Kataja; Veli-Matti Kosma; Annika Lindblom; Sara Margolin; Tuomas Heikkinen; Kati Kämpjärvi; Kirsimari Aaltonen; Heli Nevanlinna; Natalia Bogdanova; Irina Coinac; Peter Schürmann; Thilo Dörk; Claus R Bartram; Rita K Schmutzler; Sandrine Tchatchou; Barbara Burwinkel; Hiltrud Brauch; Diana Torres; Ute Hamann; Christina Justenhoven; Gloria Ribas; José I Arias; Javier Benitez; Stig E Bojesen; Børge G Nordestgaard; Henrik L Flyger; Julian Peto; Olivia Fletcher; Nichola Johnson; Isabel Dos Santos Silva; Peter A Fasching; Matthias W Beckmann; Reiner Strick; Arif B Ekici; Annegien Broeks; Marjanka K Schmidt; Flora E van Leeuwen; Laura J Van't Veer; Melissa C Southey; John L Hopper; Carmel Apicella; Christopher A Haiman; Brian E Henderson; Loic Le Marchand; Laurence N Kolonel; Vessela Kristensen; Grethe Grenaker Alnaes; David J Hunter; Peter Kraft; David G Cox; Susan E Hankinson; Caroline Seynaeve; Maaike P G Vreeswijk; Rob A E M Tollenaar; Peter Devilee; STEPHEN CHANOCK; Jolanta Lissowska; Louise Brinton; Beata Peplonska; Kamila Czene; Per Hall; Yuqing Li; Jianjun Liu; Sabapathy Balasubramanian; Saeed Rafii; Malcolm W R Reed; Karen A Pooley; Don Conroy; Caroline Baynes; Daehee Kang; Keun-Young Yoo; Dong-Young Noh; Sei-Hyun Ahn; Chen-Yang Shen; Hui-Chun Wang; Jyh-Cherng Yu; Pei-Ei Wu; Hoda Anton-Culver; Argyrios Ziogoas; Kathleen Egan; Polly Newcomb; Linda Titus-Ernstoff; Amy Trentham Dietz; Alice J Sigurdson; Bruce H Alexander; Parveen Bhatti; Kristina Allen-Brady; Lisa A Cannon-Albright; Jathine Wong; Georgia Chenevix-Trench; Amanda B Spurdle; Jonathan Beesley; Paul D P Pharoah; Doug F Easton; Montserrat Garcia-Closas
Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(5):1610-6.
2009: Shahana Ahmed; Gilles Thomas; Maya Ghoussaini; Catherine S Healey; Manjeet K Humphreys; Radka Platte; Jonathan Morrison; Melanie Maranian; Karen A Pooley; Robert Luben; Diana Eccles; D Gareth Evans; Olivia Fletcher; Nichola Johnson; Isabel dos Santos Silva; Julian Peto; Michael R Stratton; Nazneen Rahman; Kevin Jacobs; Ross Prentice; Garnet L Anderson; Aleksandar Rajkovic; J David Curb; Regina G Ziegler; Christine D Berg; Saundra S Buys; Catherine A McCarty; Heather Spencer Feigelson; Eugenia E Calle; Michael J Thun; W Ryan Diver; Stig Bojesen; Børge G Nordestgaard; Henrik Flyger; Thilo Dörk; Peter Schürmann; Peter Hillemanns; Johann H Karstens; Natalia V Bogdanova; Natalia N Antonenkova; Iosif V Zalutsky; Marina Bermisheva; Sardana Fedorova; Elza Khusnutdinova; Daehee Kang; Keun-Young Yoo; Dong Young Noh; Sei-Hyun Ahn; Peter Devilee; Christi J van Asperen; R A E M Tollenaar; Caroline Seynaeve; Montserrat Garcia-Closas; Jolanta Lissowska; Louise Brinton; Beata Peplonska; Heli Nevanlinna; Tuomas Heikkinen; Kristiina Aittomäki; Carl Blomqvist; John L Hopper; Melissa C Southey; Letitia Smith; Amanda B Spurdle; Marjanka K Schmidt; Annegien Broeks; Richard R van Hien; Sten Cornelissen; Roger L Milne; Gloria Ribas; Anna González-Neira; Javier Benitez; Rita K Schmutzler; Barbara Burwinkel; Claus R Bartram; Alfons Meindl; Hiltrud Brauch; Christina Justenhoven; Ute Hamann; Jenny Chang-Claude; Rebecca Hein; Shan Wang-Gohrke; Annika Lindblom; Sara Margolin; Arto Mannermaa; Veli-Matti Kosma; Vesa Kataja; Janet E Olson; Xianshu Wang; Zachary Fredericksen; Graham G Giles; Gianluca Severi; Laura Baglietto; Dallas R English; Susan E Hankinson; David G Cox; Peter Kraft; Lars J Vatten; Kristian Hveem; Merethe Kumle; Alice Sigurdson; Michele Doody; Parveen Bhatti; Bruce H Alexander; Maartje J Hooning; Ans M W van den Ouweland; Rogier A Oldenburg; Mieke Schutte; Per Hall; Kamila Czene; Jianjun Liu; Yuqing Li; Angela Cox; Graeme Elliott; Ian Brock; Malcolm W R Reed; Chen-Yang Shen; Jyh-Cherng Yu; Giu-Cheng Hsu; Shou-Tung Chen; Hoda Anton-Culver; Argyrios Ziogas; Irene L Andrulis; Julia A Knight; Jonathan Beesley; Ellen L Goode; Fergus J. Couch; Georgia Chenevix-Trench; Robert N Hoover; Bruce A J Ponder; David J Hunter; Paul D P Pharoah; Alison M Dunning; STEPHEN CHANOCK; Douglas F Easton
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.
Nature genetics 2009;41(5):585-90.
2009: Timothy R Rebbeck; Antonis C Antoniou; Trinidad Caldes Llopis; Heli Nevanlinna; Kristiina Aittomäki; Jacques Simard; Amanda B Spurdle; Fergus J. Couch; Lutecia H Mateus Pereira; Mark H Greene; Irene L Andrulis; Boris Pasche; Virginia Kaklamani; Ute Hamann; Csilla Szabo; Susan Peock; Margaret Cook; Patricia A Harrington; Alan Donaldson; Allison M Male; Carol Anne Gardiner; Helen Gregory; Lucy E Side; Anne C Robinson; Louise Emmerson; Ian Ellis; Jean-Philippe Peyrat; Joëlle Fournier; Philippe Vennin; Claude Adenis; Danièle Muller; Jean-Pierre Fricker; Michel Longy; Olga M Sinilnikova; Dominique Stoppa-Lyonnet; Rita K Schmutzler; Beatrix Versmold; Christoph Engel; Alfons Meindl; Karin Kast; Dieter Schaefer; Ursula G Froster; Georgia Chenevix-Trench; Douglas F Easton
No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study.
Breast cancer research and treatment 2009;115(1):185-92.
2009: Alison M Dunning; Catherine S Healey; Caroline Baynes; Ana-Teresa Maia; Serena Scollen; Ana Vega; Raquel Rodríguez; Nuno L Barbosa-Morais; bruce ponder; Yen-Ling Low; Sheila Bingham; Christopher A Haiman; Loic Le Marchand; Annegien Broeks; Marjanka K Schmidt; John Hopper; Melissa Southey; Matthias W Beckmann; Peter A Fasching; Julian Peto; Nichola Johnson; Stig E Bojesen; Børge Nordestgaard; Roger L Milne; Javier Benitez; Ute Hamann; Yon Ko; Rita K Schmutzler; Barbara Burwinkel; Peter Schürmann; Thilo Dörk; Tuomas Heikkinen; Heli Nevanlinna; Annika Lindblom; Sara Margolin; Arto Mannermaa; Veli-Matti Kosma; Xiaoqing Chen; Amanda Spurdle; Jenny Change-Claude; Dieter Flesch-Janys; Fergus J. Couch; Janet E Olson; Gianluca Severi; Laura Baglietto; Anne-Lise Børresen-Dale; Vessela Kristensen; David J Hunter; Susan E Hankinson; Peter Devilee; Maaike Vreeswijk; Jolanta Lissowska; Louise Brinton; Jianjun Liu; Per Hall; Daehee Kang; Keun-Young Yoo; Chen-Yang Shen; Jyh-Cherng Yu; Hoda Anton-Culver; Argyrios Ziogoas; Alice Sigurdson; Jeff Struewing; Douglas F Easton; Montserrat Garcia-Closas; Manjeet K Humphreys; Jonathan Morrison; Paul D P Pharoah; Karen A Pooley; Georgia Chenevix-Trench
Association of ESR1 gene tagging SNPs with breast cancer risk.
Human molecular genetics 2009;18(6):1131-9.
2008: Jinhua Wang; Chunjing Bian; Jing Li; Fergus J. Couch; Kangjian Wu; Robert Chunhua Zhao
Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter.
The Journal of biological chemistry 2008;283(52):36249-56.
2008: Vitaly Balan; Pratima Nangia-Makker; Ann Grossbart Schwartz; Young Suk Jung; Larry Tait; Victor Hogan; Tirza Raz; Yi Wang; Zeng-Quan Yang; Gen Sheng Wu; Yongjun Guo; Huixiang Li; Judith Abrams; Fergus J. Couch; Wilma L Lingle; Ricardo V Lloyd; Stephen Ethier; Michael A Tainsky; Avraham Raz
Racial disparity in breast cancer and functional germ line mutation in galectin-3 (rs4644): a pilot study.
Cancer research 2008;68(24):10045-50.
2008: Andrew D Spearman; Kevin M Sweet; Xiao-Ping Zhou; Jane McLennan; Fergus J. Couch; Amanda E. Toland
Clinically applicable models to characterize BRCA1 and BRCA2 variants of uncertain significance.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(33):5393-400.
2008: Fergus J. Couch; Lene Juel Rasmussen; Robert Hofstra; Alvaro N A Monteiro; Marc S Greenblatt; Niels De Wind
Assessment of functional effects of unclassified genetic variants.
Human mutation 2008;29(11):1314-26.
2008: Amanda B Spurdle; Fergus J. Couch; Frans B L Hogervorst; Paolo Radice; Olga M Sinilnikova
Prediction and assessment of splicing alterations: implications for clinical testing.
Human mutation 2008;29(11):1304-13.
2008: Matthew P Goetz; Vera J Suman; Fergus J. Couch; Matthew M Ames; James M Rae; Mark G Erlander; Xiao-Jun Ma; Dennis C Sgroi; Carol A Reynolds; Wilma L Lingle; Richard M Weinshilboum; David A Flockhart; Zeruesenay Desta; Edith A Perez; James N Ingle
Cytochrome P450 2D6 and homeobox 13/interleukin-17B receptor: combining inherited and tumor gene markers for prediction of tamoxifen resistance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5864-8.
2008: Xianshu Wang; Ellen L Goode; Zachary S Fredericksen; Robert A Vierkant; V Shane Pankratz; Wen Liu; David N Rider; Celine M Vachon; James Cerhan; Janet E Olson; Fergus J. Couch
Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(8):2101-8.
2008: Steven A Narod; Susan L Neuhausen; G Vichodez; S Armel; Henry T Lynch; Parviz Ghadirian; S Cummings; Olufunmilayo I Olopade; D Stoppa-Lyonnet; Fergus J. Couch; T Wagner; Ellen Warner; William D Foulkes; Howard M Saal; Jeffrey N Weitzel; A Tulman; A Poll; R Nam; P Sun; Jessica Danquah; Susan Domchek; Nadine Tung; Peter Ainsworth; Douglas Horsman; Charmaine Kim-Sing; Christine Maugard; Andrea Eisen; Mary Daly; Wendy McKinnon; Marie Wood; Claudine Isaacs; Dawna Gilchrist; Beth Y Karlan; Raluca Nedelcu; Wendy Meschino; Judy Garber; Barbara Pasini; Siranoush Manoukian; Christina Bellati
Rapid progression of prostate cancer in men with a BRCA2 mutation.
British journal of cancer 2008;99(2):371-4.
2008: Naomi M Gades; Akihiro Ohash; Lisa D. Mills; Matt A Rowley; Kelly S Predmore; Ronald J Marler; Fergus J. Couch
Spontaneous vulvar papillomas in a colony of mice used for pancreatic cancer research.
Comparative medicine 2008;58(3):271-5.
2008: Daniel J Farrugia; Mukesh K Agarwal; Vernon S Pankratz; Amie M Deffenbaugh; Dmitry Pruss; Cynthia Frye; Linda Wadum; Kiley Johnson; Jennifer Mentlick; Sean V Tavtigian; David E Goldgar; Fergus J. Couch
Functional assays for classification of BRCA2 variants of uncertain significance.
Cancer research 2008;68(9):3523-31.
2008: Kelly A Metcalfe; Daphna Birenbaum-Carmeli; Jan Lubinski; Jacek Gronwald; Henry Lynch; Pal Moller; Parviz Ghadirian; William D Foulkes; Jan Klijn; Eitan Friedman; Charmaine Kim-Sing; Peter Ainsworth; Barry Rosen; Susan M Domchek; Teresa Wagner; Nadine Tung; Siranoush Manoukian; Fergus J. Couch; Ping Sun; Steven A Narod
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2008;122(9):2017-22.
2008: Montserrat Garcia-Closas; Per Hall; Heli Nevanlinna; Karen Pooley; Jonathan Morrison; Douglas A Richesson; Stig E Bojesen; Børge G Nordestgaard; Christen K Axelsson; Jose I Arias; Roger L Milne; Gloria Ribas; Anna González-Neira; Javier Benítez; Pilar Zamora; Hiltrud Brauch; Christina Justenhoven; Ute Hamann; Yon-Dschun Ko; Thomas Bruening; Susanne Haas; Thilo Dörk; Peter Schürmann; Peter Hillemanns; Natalia Bogdanova; Michael Bremer; Johann Hinrich Karstens; Rainer Fagerholm; Kirsimari Aaltonen; Kristiina Aittomäki; Karl von Smitten; Carl Blomqvist; Arto Mannermaa; Matti Uusitupa; Matti Eskelinen; Maria Tengström; Veli-Matti Kosma; Vesa Kataja; Georgia Chenevix-Trench; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Peter Devilee; Christi J van Asperen; Catharina E Jacobi; Rob A E M Tollenaar; Petra E A Huijts; Jan G M Klijn; Jenny Chang-Claude; Silke Kropp; Tracy Slanger; Dieter Flesch-Janys; Elke Mutschelknauss; Ramona Salazar; Shan Wang-Gohrke; Fergus J. Couch; Ellen L Goode; Janet E Olson; Celine Vachon; Zachary S Fredericksen; Graham G Giles; Laura Baglietto; Gianluca Severi; John L Hopper; Dallas R English; Melissa C Southey; Christopher A Haiman; Brian Henderson; Laurence N Kolonel; Loic Le Marchand; Daniel O Stram; David J Hunter; Susan E Hankinson; David G Cox; Rulla Tamimi; Peter Kraft; Mark E Sherman; STEPHEN CHANOCK; Jolanta Lissowska; Louise A Brinton; Beata Peplonska; Jan G M Klijn; Maartje J Hooning; Han Meijers-Heijboer; J Margriet Collee; Ans van den Ouweland; Andre G Uitterlinden; Jianjun Liu; Low Yen Lin; Li Yuqing; Keith Humphreys; Kamila Czene; Angela Cox; Sabapathy P Balasubramanian; Simon Cross; Malcolm W R Reed; Fiona Blows; Kristy Driver; Alison Dunning; Jonathan Tyrer; bruce ponder; Suleeporn Sangrajrang; Paul Brennan; James McKay; Fabrice Odefrey; Valerie Gabrieau; Alice Sigurdson; Michele Doody; Jeffrey P Struewing; Bruce Alexander; Douglas F Easton; Paul D Pharoah
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.
PLoS genetics 2008;4(4):e1000054.
2008: Antonis C Antoniou; Amanda B Spurdle; Olga M Sinilnikova; Sue Healey; Karen A Pooley; Rita K Schmutzler; Beatrix Versmold; Christoph Engel; Alfons Meindl; Norbert Arnold; Wera Hofmann; Christian Sutter; Dieter Niederacher; Helmut Deissler; Trinidad Caldes; Kati Kämpjärvi; Heli Nevanlinna; Jacques Simard; Jonathan Beesley; Xiaoqing Chen; Susan L Neuhausen; Timothy R Rebbeck; Theresa Wagner; Henry T Lynch; Claudine Isaacs; Jeffrey N Weitzel; Patricia Anne Ganz; Mary B Daly; Gail Tomlinson; Olufunmilayo I Olopade; Joanne L Blum; Fergus J. Couch; Paolo Peterlongo; Siranoush Manoukian; Monica Barile; Paolo Radice; Csilla I Szabo; Lutecia H Mateus Pereira; Mark H Greene; Gad Rennert; Flavio Lejbkowicz; Ofra Barnett-Griness; Irene L Andrulis; Hilmi Ozcelik; Anne-Marie Gerdes; Maria A Caligo; Yael Laitman; Bella Kaufman; Roni Milgrom; Eitan Friedman; Susan M Domchek; Katherine L Nathanson; Ana Osorio; Gemma Llort; Roger L Milne; Javier Benítez; Ute Hamann; Frans B L Hogervorst; Peggy Manders; Marjolijn J L Ligtenberg; Ans M W van den Ouweland; Susan Peock; Margaret Cook; Radka Platte; D Gareth Evans; Rosalind Eeles; Gabriella Pichert; Carol Chu; Diana Eccles; Rosemarie Davidson; Fiona Douglas; Andrew K Godwin; Laure Barjhoux; Sylvie Mazoyer; Hagay Sobol; Violaine Bourdon; François Eisinger; Agnès Chompret; Corinne Capoulade; Brigitte Bressac-de Paillerets; Gilbert M Lenoir; Marion Gauthier-Villars; Claude Houdayer; Dominique Stoppa-Lyonnet; Georgia Chenevix-Trench; Douglas F Easton
Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
American journal of human genetics 2008;82(4):937-48.
2008: Wataru Sakai; Elizabeth M Swisher; Beth Y Karlan; Mukesh K Agarwal; Jake Higgins; Cynthia Friedman; Emily Villegas; Céline Jacquemont; Daniel J Farrugia; Fergus J. Couch; Nicole Urban; Toshiyasu Taniguchi
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers.
Nature 2008;451(7182):1116-20.
2008: Xianshu Wang; Csilla Szabo; Chiping Qian; Peter G Amadio; Stephen N Thibodeau; James Cerhan; Gloria M Petersen; Wanguo Liu; Fergus J. Couch
Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers.
Cancer research 2008;68(4):971-5.
2008: Rachel Karchin; Mukesh Agarwal; Andrej Sali; Fergus J. Couch; Mary Beattie
Classifying Variants of Undetermined Significance in BRCA2 with protein likelihood ratios.
Cancer informatics 2008;6():203-16.
2008: Linda E Kelemen; Fergus J. Couch; Shahana Ahmed; Alison M Dunning; Paul D P Pharoah; Douglas F Easton; Zachary S Fredericksen; Robert A Vierkant; V Shane Pankratz; Ellen L Goode; Christopher G Scott; David N Rider; Xianshu Wang; James R Cerhan; Celine M Vachon
Genetic variation in stromal proteins decorin and lumican with breast cancer: investigations in two case-control studies.
Breast cancer research : BCR 2008;10(6):R98.
2008: Aik Choon Tan; Jian-Bing Fan; Collins Karikari; Marina Bibikova; Eliza Wickham Garcia; Lixin Zhou; David Barker; david serre; Georg Feldmann; Ralph Hruban; Alison P Klein; Michael Goggins; Fergus J. Couch; Thomas J Hudson; Raimond L Winslow; Anirban Maitra; Aravinda Chakravarti
Allele-specific expression in the germline of patients with familial pancreatic cancer: an unbiased approach to cancer gene discovery.
Cancer biology & therapy 2008;7(1):135-44.
2007: Tara Friebel; Susan M Domchek; Susan L Neuhausen; Theresa Wagner; D Gareth Evans; Claudine Isaacs; Judy E Garber; Mary B Daly; Rosalind Eeles; Ellen Matloff; Gail Tomlinson; Henry T Lynch; Nadine Tung; Joanne L Blum; Jeffrey N Weitzel; Wendy S Rubinstein; Patricia Anne Ganz; Fergus J. Couch; Timothy R Rebbeck
Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers.
Clinical breast cancer 2007;7(11):875-82.
2007: Antonis C Antoniou; Olga M Sinilnikova; Jacques Simard; Mélanie Léoné; Martine Dumont; Susan L Neuhausen; Jeffery P Struewing; Dominique Stoppa-Lyonnet; Laure Barjhoux; David J Hughes; Isabelle Coupier; Muriel Belotti; Christine Lasset; Valérie Bonadona; Yves-Jean Bignon; Timothy R Rebbeck; Theresa Wagner; Henry T Lynch; Susan M Domchek; Katherine L Nathanson; Judy E Garber; Jeffrey N Weitzel; steven narod; Gail Tomlinson; Olufunmilayo I Olopade; Andrew Godwin; Claudine Isaacs; Anna Jakubowska; Jan Lubinski; Jacek Gronwald; Bohdan Górski; Tomasz Byrski; Tomasz Huzarski; Susan Peock; Margaret Cook; Caroline Baynes; Alexandra Murray; Mark Rogers; Peter A Daly; Huw Dorkins; Rita K Schmutzler; Beatrix Versmold; Christoph Engel; Alfons Meindl; Norbert Arnold; Dieter Niederacher; Helmut Deissler; Amanda B Spurdle; Xiaoqing Chen; Nicola Waddell; Nicole Cloonan; Tomas Kirchhoff; Kenneth Offit; Eitan Friedman; Bella Kaufmann; Yael Laitman; Gilli Galore; Gad Rennert; Flavio Lejbkowicz; Leonid Raskin; Irene L Andrulis; Eduard Ilyushik; Hilmi Ozcelik; Peter Devilee; Maaike P G Vreeswijk; Mark H Greene; Sheila A Prindiville; Ana Osorio; Javier Benitez; Michal Zikan; Csilla I Szabo; Outi Kilpivaara; Heli Nevanlinna; Ute Hamann; Francine Durocher; Adalgeir Arason; Fergus J. Couch; Douglas F Easton; Georgia Chenevix-Trench
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.
American journal of human genetics 2007;81(6):1186-200.
2007: Alison M Hosey; Julia J Gorski; Margaret M Murray; Jennifer E Quinn; Wen Y Chung; Gail E Stewart; Colin R James; Susan M Farragher; Jude M Mulligan; A N J Scott; Peter A Dervan; Patrick G Johnston; Fergus J. Couch; Peter A Daly; Elaine Kay; Amanda McCann; Paul B Mullan; D Paul Harkin
Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.
Journal of the National Cancer Institute 2007;99(22):1683-94.
2007: Douglas F Easton; Amie M Deffenbaugh; Dmitry Pruss; Cynthia Frye; Richard J Wenstrup; Kristina Allen-Brady; Sean V Tavtigian; Alvaro Monteiro; Edwin S Iversen; Fergus J. Couch; David E Goldgar
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
American journal of human genetics 2007;81(5):873-83.
2007: Joanne Kotsopoulos; Jan Lubinski; Henry T Lynch; Jan Klijn; Parviz Ghadirian; Susan L Neuhausen; Charmaine Kim-Sing; William D Foulkes; Pal Moller; Claudine Isaacs; Susan Domchek; Susan Randall; Kenneth Offit; Nadine Tung; Peter Ainsworth; Ruth Gershoni-Baruch; Andrea Eisen; Mary Daly; Beth Y Karlan; Howard M Saal; Fergus J. Couch; Barbara Pasini; Teresa Wagner; Eitan Friedman; Gad Rennert; Charis Eng; Jeffrey N Weitzel; Ping Sun; steven narod; Judy E Garber; M Osborne; D Fishman; J McLennan; W McKinnon; Sofia D Merajver; H Olsson; D Provencher; B Pasche; G Evans; W S Meschino; E Lemire; A Chudley; D Rayson; C Bellati
Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Breast cancer research and treatment 2007;105(2):221-8.
2007: Celine M Vachon; Thomas A Sellers; Erin E Carlson; Julie M Cunningham; Christopher A Hilker; Regenia L Smalley; Daniel J Schaid; Linda E Kelemen; Fergus J. Couch; V Shane Pankratz
Strong evidence of a genetic determinant for mammographic density, a major risk factor for breast cancer.
Cancer research 2007;67(17):8412-8.
2007: Thomas A Sellers; Celine M Vachon; V Shane Pankratz; Carol A Janney; Zachary S Fredericksen; Kathleen R Brandt; Y Huang; Fergus J. Couch; Lawrence H Kushi; James Cerhan
Association of childhood and adolescent anthropometric factors, physical activity, and diet with adult mammographic breast density.
American journal of epidemiology 2007;166(4):456-64.
2007: Fergus J. Couch; Olga Sinilnikova; Robert A Vierkant; V Shane Pankratz; Zachary S Fredericksen; Dominique Stoppa-Lyonnet; Isabelle Coupier; David Hughes; Agnès Hardouin; Pascaline Berthet; Susan Peock; Margaret Cook; Caroline Baynes; Shirley Hodgson; Patrick J Morrison; Mary E Porteous; Anna Jakubowska; Jan Lubinski; Jacek Gronwald; Amanda B Spurdle; Rita Schmutzler; Beatrix Versmold; Christoph Engel; Alfons Meindl; Christian Sutter; Jurgen Horst; Dieter Schaefer; Kenneth Offit; Tomas Kirchhoff; Irene L Andrulis; Eduard Ilyushik; Gordon Glendon; Peter Devilee; Maaike P G Vreeswijk; Hans Vasen; Ake Borg; Katja Backenhorn; Jeffery P Struewing; Mark H Greene; Susan L Neuhausen; Timothy R Rebbeck; Katherine Nathanson; Susan Domchek; Theresa Wagner; Judy E Garber; Csilla Szabo; Michal Zikan; Lenka Foretova; Janet E Olson; Thomas A Sellers; Noralane Lindor; Heli Nevanlinna; Johanna Tommiska; Kristiina Aittomaki; Ute Hamann; M Rashid; Diana Torres; Jacques Simard; Francine Durocher; Frederic Guenard; Henry T Lynch; Claudine Isaacs; Jeffrey N Weitzel; Olufunmilayo I Olopade; steven narod; Mary B Daly; Andrew K Godwin; Gail Tomlinson; Douglas F Easton; Georgia Chenevix-Trench; Antonis C Antoniou
AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(7):1416-21.
2007: Douglas F Easton; Karen A Pooley; Alison M Dunning; Paul D P Pharoah; Deborah Thompson; Dennis G Ballinger; Jeffery P Struewing; Jonathan Morrison; Helen Field; Robert Luben; Nicholas Wareham; Shahana Ahmed; Catherine S Healey; Richard Bowman; Kerstin B Meyer; Christopher A Haiman; Laurence K Kolonel; Brian Henderson; Loic Le Marchand; Paul Brennan; Suleeporn Sangrajrang; Valerie Gaborieau; Fabrice Odefrey; Chen-Yang Shen; Pei-Ei Wu; Hui-Chun Wang; Diana Eccles; D Gareth Evans; Julian Peto; Olivia Fletcher; Nichola Johnson; Sheila Seal; Michael R Stratton; Nazneen Rahman; Georgia Chenevix-Trench; Stig E Bojesen; Børge G Nordestgaard; Christen K Axelsson; Montserrat Garcia-Closas; Louise Brinton; STEPHEN CHANOCK; Jolanta Lissowska; Beata Peplonska; Heli Nevanlinna; Rainer Fagerholm; Hannaleena Eerola; Daehee Kang; Keun-Young Yoo; Dong-Young Noh; Sei-Hyun Ahn; David J Hunter; Susan E Hankinson; David G Cox; Per Hall; Sara Wedren; Jianjun Liu; Yen-Ling Low; Natalia Bogdanova; Peter Schürmann; Thilo Dörk; Rob A E M Tollenaar; Catharina E Jacobi; Peter Devilee; Jan G M Klijn; Alice J Sigurdson; Michele M Doody; Bruce H Alexander; Jinghui Zhang; Angela Cox; Ian W Brock; Gordon MacPherson; Malcolm W R Reed; Fergus J. Couch; Ellen L Goode; Janet E Olson; Hanne Meijers-Heijboer; Ans van den Ouweland; André Uitterlinden; Fernando Rivadeneira; Roger L Milne; Gloria Ribas; Anna Gonzalez-Neira; Javier Benitez; John L Hopper; Margaret McCredie; Melissa Southey; Graham G Giles; Chris Schroen; Christina Justenhoven; Hiltrud Brauch; Ute Hamann; Yon-Dschun Ko; Amanda B Spurdle; Jonathan Beesley; Xiaoqing Chen; Arto Mannermaa; Veli-Matti Kosma; Vesa Kataja; Jaana Hartikainen; Nicholas E Day; David R Cox; bruce ponder
Genome-wide association study identifies novel breast cancer susceptibility loci.
Nature 2007;447(7148):1087-93.
2007: Simon A Gayther; Honglin Song; Susan J Ramus; Susan Krüger Kjaer; Alice S Whittemore; Lydia Quaye; Jonathan Tyrer; Danielle Shadforth; Estrid Hogdall; Claus Hogdall; Jan Blaeker; Richard DiCioccio; Valerie McGuire; Penelope M Webb; Jonathan Beesley; Adele C Green; David C Whiteman; Marc T Goodman; Galina Lurie; Michael E Carney; Francesmary Modugno; Roberta B Ness; Robert P Edwards; Kirsten B Moysich; Ellen L Goode; Fergus J. Couch; Julie M Cunningham; Thomas A Sellers; Anna H Wu; Malcolm Pike; Edwin S Iversen; Jeffrey R Marks; Montserrat Garcia-Closas; Louise Brinton; Jolanta Lissowska; Beata Peplonska; Douglas F Easton; Ian Jacobs; bruce ponder; Joellen Schildkraut; Celeste L Pearce; Georgia Chenevix-Trench; Andrew Berchuck; Paul D P Pharoah
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer.
Cancer research 2007;67(7):3027-35.
2007: Janet E Olson; James N Ingle; Cynthia X Ma; Linda L Pelleymounter; Daniel J Schaid; V Shane Pankratz; Robert A Vierkant; Zachary S Fredericksen; Yanhong Wu; Fergus J. Couch; Celine M Vachon; Thomas A Sellers; Richard M Weinshilboum
A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches.
Breast cancer research and treatment 2007;102(2):237-47.
2007: Janet E Olson; Cynthia X Ma; Linda L Pelleymounter; Daniel J Schaid; V Shane Pankratz; Robert A Vierkant; Zachary S Fredericksen; James N Ingle; Yanhong Wu; Fergus J. Couch; Thomas A Sellers; Richard M Weinshilboum; Celine M Vachon
A comprehensive examination of CYP19 variation and breast density.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(3):623-5.
2007: Angela Cox; Alison M Dunning; Montserrat Garcia-Closas; Sabapathy Balasubramanian; Malcolm W R Reed; Karen A Pooley; Serena Scollen; Caroline Baynes; bruce ponder; STEPHEN CHANOCK; Jolanta Lissowska; Louise Brinton; Beata Peplonska; Melissa C Southey; John L Hopper; Margaret R E McCredie; Graham G Giles; Olivia Fletcher; Nichola Johnson; Isabel dos Santos Silva; Lorna Gibson; Stig E Bojesen; Børge G Nordestgaard; Christen K Axelsson; Diana Torres; Ute Hamann; Christina Justenhoven; Hiltrud Brauch; Jenny Chang-Claude; Silke Kropp; Angela Risch; Shan Wang-Gohrke; Peter Schürmann; Natalia Bogdanova; Thilo Dörk; Rainer Fagerholm; Kirsimari Aaltonen; Carl Blomqvist; Heli Nevanlinna; Sheila Seal; Anthony Renwick; Michael R Stratton; Nazneen Rahman; Suleeporn Sangrajrang; David Hughes; Fabrice Odefrey; Paul Brennan; Amanda B Spurdle; Georgia Chenevix-Trench; Jonathan Beesley; Arto Mannermaa; Jaana Hartikainen; Vesa Kataja; Veli-Matti Kosma; Fergus J. Couch; Janet E Olson; Ellen L Goode; Annegien Broeks; Marjanka K Schmidt; Frans B L Hogervorst; Laura J Van't Veer; Daehee Kang; Keun-Young Yoo; Dong-Young Noh; Sei-Hyun Ahn; Sara Wedrén; Per Hall; Yen-Ling Low; Jianjun Liu; Roger L Milne; Gloria Ribas; Anna Gonzalez-Neira; Javier Benitez; Alice J Sigurdson; Denise L Stredrick; Bruce H Alexander; Jeffery P Struewing; Paul D P Pharoah; Douglas F Easton
A common coding variant in CASP8 is associated with breast cancer risk.
Nature genetics 2007;39(3):352-8.
2007: Marcelo A Carvalho; Sylvia M Marsillac; Rachel Karchin; Siranoush Manoukian; Scott Grist; Ramona F Swaby; Turan P Urmenyi; Edson Rondinelli; Rosane Silva; Luis Gayol; Lisa Baumbach; Rebecca Sutphen; Jennifer L Pickard-Brzosowicz; Katherine L Nathanson; Andrej Sali; David E Goldgar; Fergus J. Couch; Paolo Radice; Alvaro Monteiro
Determination of cancer risk associated with germ line BRCA1 missense variants by functional analysis.
Cancer research 2007;67(4):1494-501.
2007: Matthew P Goetz; James N Ingle; Fergus J. Couch
Gene-expression-based predictors for breast cancer.
The New England journal of medicine 2007;356(7):752; author reply 752-3.
2007: Fergus J. Couch; Michele R Johnson; Kari G Rabe; Kieran Brune; Mariza de Andrade; Michael Goggins; Heidi Rothenmund; Steven Gallinger; Alison P Klein; Gloria M Petersen; Ralph Hruban
The prevalence of BRCA2 mutations in familial pancreatic cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(2):342-6.
2007: Paul K Lovelock; Amanda B Spurdle; Myth T S Mok; Daniel J Farrugia; Sunil R Lakhani; Sue Healey; Stephen Arnold; Daniel Buchanan; Fergus J. Couch; Beric R Henderson; David E Goldgar; Sean V Tavtigian; Georgia Chenevix-Trench; Melissa A Brown
Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants?
Breast cancer research : BCR 2007;9(6):R82.
2007: Georgia Chenevix-Trench; Roger L Milne; Antonis C Antoniou; Fergus J. Couch; Douglas F Easton; David E Goldgar
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA).
Breast cancer research : BCR 2007;9(2):104.
2007: Matthew P Goetz; Stacey K Knox; Vera J Suman; James M Rae; Stephanie L Safgren; Matthew M Ames; Daniel W Visscher; Carol Reynolds; Fergus J. Couch; Wilma L Lingle; Richard M Weinshilboum; Emily G Barr Fritcher; Andrea M Nibbe; Zeruesenay Desta; Anne Nguyen; David A Flockhart; Edith A Perez; James N Ingle
The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.
Breast cancer research and treatment 2007;101(1):113-21.
2007: Marcelo A Carvalho; Fergus J. Couch; Alvaro Monteiro
Functional assays for BRCA1 and BRCA2.
The international journal of biochemistry & cell biology 2007;39(2):298-310.
2006: Jun Zhang; Xianshu Wang; Chia-Ju Lin; Fergus J. Couch; Peiwen Fei
Altered expression of FANCL confers mitomycin C sensitivity in Calu-6 lung cancer cells.
Cancer biology & therapy 2006;5(12):1632-6.
2006: Xianshu Wang; Fengwei Wang; Ken Taniguchi; Ratnam S Seelan; Liang Wang; Katherine E Zarfas; Shannon K McDonnell; Chiping Qian; Kaifeng Pan; Youyong Lu; Viji Shridhar; Fergus J. Couch; Donald J Tindall; Jennifer L Beebe; Kathleen Cooney; William B Isaacs; Steven J Jacobsen; Daniel J Schaid; Stephen N Thibodeau; Wanguo Liu
Truncating variants in p53AIP1 disrupting DNA damage-induced apoptosis are associated with prostate cancer risk.
Cancer research 2006;66(21):10302-7.
2006: Amy Finch; Mario E Beiner; Jan Lubinski; Henry T Lynch; Pal Moller; Barry Rosen; Joan Murphy; Parviz Ghadirian; Eitan Friedman; William D Foulkes; Charmaine Kim-Sing; Teresa Wagner; Nadine Tung; Fergus J. Couch; Dominique Stoppa-Lyonnet; Peter Ainsworth; Mary Daly; Barbara Pasini; Ruth Gershoni-Baruch; Charis Eng; Olufunmilayo I Olopade; Jane McLennan; Beth Y Karlan; Jeffrey N Weitzel; Ping Sun; Steven A Narod
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.
JAMA : the journal of the American Medical Association 2006;296(2):185-92.
2006: Paula Smith; Lesley McGuffog; Douglas F Easton; Graham J Mann; Gulietta M Pupo; Beth Newman; Georgia Chenevix-Trench; Csilla Szabo; Melissa Southey; Hélène Renard; Fabrice Odefrey; Henry Lynch; Dominique Stoppa-Lyonnet; Fergus J. Couch; John L Hopper; Graham G Giles; Margaret R E McCredie; Saundra Buys; Irene Andrulis; Ruby Senie; David E Goldgar; Rogier Oldenburg; Karin Kroeze-Jansema; Jaennelle Kraan; Hanne Meijers-Heijboer; Jan G M Klijn; Christi van Asperen; Inge van Leeuwen; Hans Vasen; Cees J Cornelisse; Peter Devilee; Linda Baskcomb; Sheila Seal; Rita Barfoot; Jon Mangion; Anita Hall; Sarah Edkins; Elizabeth Rapley; Richard Wooster; Jenny Chang-Claude; Diana Eccles; D Gareth Evans; P Andrew Futreal; Katherine L Nathanson; Barbara L Weber; Nazneen Rahman; Michael R Stratton
A genome wide linkage search for breast cancer susceptibility genes.
Genes, chromosomes & cancer 2006;45(7):646-55.
2006: Bing Xia; Qing Sheng; Koji Nakanishi; Akihiro Ohashi; Jianmin Wu; Nicole Christ; Xinggang Liu; Maria Jasin; Fergus J. Couch; David M Livingston
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
Molecular cell 2006;22(6):719-29.
2006: Matthew P Goetz; Vera J Suman; James N Ingle; Andrea M Nibbe; Daniel W Visscher; Carol A Reynolds; Wilma L Lingle; Mark G Erlander; Xiao-Jun Ma; Dennis C Sgroi; Edith A Perez; Fergus J. Couch
A two-gene expression ratio of homeobox 13 and interleukin-17B receptor for prediction of recurrence and survival in women receiving adjuvant tamoxifen.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(7 Pt 1):2080-7.
2006: Alvaro Monteiro; Fergus J. Couch
Cancer risk assessment at the atomic level.
Cancer research 2006;66(4):1897-9.
2006: Paul K Lovelock; Sue Healey; W Au; Eleanor Y M Sum; Andrea Tesoriero; Ee Ming Wong; Shannon R Hinson; R Brinkworth; A Bekessy; O Diez; Louise Izatt; Ellen Solomon; M Jenkins; Helene Renard; J Hopper; P Waring; Sean V Tavtigian; David E Goldgar; Geoffrey J Lindeman; Jane E Visvader; Fergus J. Couch; B R Henderson; Melissa C Southey; Georgia Chenevix-Trench; Amanda B Spurdle; Melissa A Brown
Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants.
Journal of medical genetics 2006;43(1):74-83.
2005: Matthew P Goetz; James M Rae; Vera J Suman; Stephanie L Safgren; Matthew M Ames; Daniel W Visscher; Carol Reynolds; Fergus J. Couch; Wilma L Lingle; David A Flockhart; Zeruesenay Desta; Edith A Perez; James N Ingle
Pharmacogenetics of tamoxifen biotransformation is associated with clinical outcomes of efficacy and hot flashes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(36):9312-8.
2005: Carey A Cullinane; Jan Lubinski; Susan L Neuhausen; Parviz Ghadirian; Henry T Lynch; Claudine Isaacs; Barbara Weber; Pal Moller; Kenneth Offit; Charmaine Kim-Sing; Eitan Friedman; Susan Randall; Barbara Pasini; Peter Ainsworth; Ruth Gershoni-Baruch; William D Foulkes; Jan Klijn; Nadine Tung; Gad Rennert; Olufunmilayo I Olopade; Fergus J. Couch; Teresa Wagner; Håkan Olsson; Ping Sun; Jeffrey N Weitzel; Steven A Narod
Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.
International journal of cancer. Journal international du cancer 2005;117(6):988-91.
2005: Matthew Goetz; Fergus J. Couch
Targeted Therapy for BRCA2 Deficient Tumors.
Cancer biology & therapy 2005;4(7):707-8.
2005: R Ward; M Johnson; Viji Shridhar; J van Deursen; Fergus J. Couch
CBP truncating mutations in ovarian cancer.
Journal of medical genetics 2005;42(6):514-8.
2005: Sean T Martin; Hiroyuki Matsubayashi; Carmelle D Rogers; Juliet Philips; Fergus J. Couch; Kieran Brune; Charles J Yeo; Scott E Kern; Ralph Hruban; Michael Goggins
Increased prevalence of the BRCA2 polymorphic stop codon K3326X among individuals with familial pancreatic cancer.
Oncogene 2005;24(22):3652-6.
2005: Akihiro Ohashi; Malgorzata Z Zdzienicka; Junjie Chen; Fergus J. Couch
Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
The Journal of biological chemistry 2005;280(15):14877-83.
2005: Kangjian Wu; Shannon R Hinson; Akihiro Ohashi; Daniel Farrugia; Patricia Wendt; Sean V Tavtigian; Amie M Deffenbaugh; David E Goldgar; Fergus J. Couch
Functional evaluation and cancer risk assessment of BRCA2 unclassified variants.
Cancer research 2005;65(2):417-26.
2005: Fergus J. Couch; Michele R Johnson; Kari Rabe; Lisa A Boardman; Robert McWilliams; Mariza de Andrade; Gloria Petersen
Germ line Fanconi anemia complementation group C mutations and pancreatic cancer.
Cancer research 2005;65(2):383-6.
2004: Carmelle D Rogers; Fergus J. Couch; Kieran Brune; Sean T Martin; Juliet Philips; KATHLEEN MURPHY; G Petersen; Charles J Yeo; Ralph Hruban; Michael Goggins
Genetics of the FANCA gene in familial pancreatic cancer.
Journal of medical genetics 2004;41(12):e126.
2004: David E Goldgar; Douglas F Easton; Amie M Deffenbaugh; Alvaro Monteiro; Sean V Tavtigian; Fergus J. Couch
Integrated evaluation of DNA sequence variants of unknown clinical significance: application to BRCA1 and BRCA2.
American journal of human genetics 2004;75(4):535-44.
2004: Camilo Adem; Cheryl L Soderberg; Kari Hafner; Carol Reynolds; Jeffrey M Slezak; Colleen S Sinclair; Thomas A Sellers; Daniel J Schaid; Fergus J. Couch; Lynn C Hartmann; Robert B Jenkins
ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers.
Genes, chromosomes & cancer 2004;41(1):1-11.
2004: Dylan V Miller; Alexey A Leontovich; Wilma L Lingle; Vera J Suman; Maureen L Mertens; James Lillie; Kimberly A Ingalls; Edith A Perez; James N Ingle; Fergus J. Couch; Daniel W Visscher
Utilizing Nottingham Prognostic Index in microarray gene expression profiling of breast carcinomas.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(7):756-64.
2004: Fergus J. Couch
Genetic epidemiology of BRCA1.
Cancer biology & therapy 2004;3(6):509-14.
2004: Matthew Rowley; Erin Grothey; Fergus J. Couch
The role of Tbx2 and Tbx3 in mammary development and tumorigenesis.
Journal of mammary gland biology and neoplasia 2004;9(2):109-18.
2004: Jeremy Chien; Julie Staub; Shou-Ih Hu; Michele Erickson-Johnson; Fergus J. Couch; David I Smith; Robert M Crowl; Scott H Kaufmann; Viji Shridhar
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer.
Oncogene 2004;23(8):1636-44.
2003: Kangjian Wu; Shi-Wen (Albert) Jiang; Fergus J. Couch
p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mRNA and protein levels in response to DNA damage.
The Journal of biological chemistry 2003;278(18):15652-60.
2003: Colleen S Sinclair; Matthew Rowley; Ali Naderi; Fergus J. Couch
The 17q23 amplicon and breast cancer.
Breast cancer research and treatment 2003;78(3):313-22.
2002: steven narod; Marie-Pierre Dubé; Jan Klijn; Jan Lubinski; Henry T Lynch; Parviz Ghadirian; Diane Provencher; Ketil Heimdal; Pal Moller; Mark Robson; Kenneth Offit; Claudine Isaacs; Barbara Weber; Eitan Friedman; Ruth Gershoni-Baruch; Gad Rennert; Barbara Pasini; Theresa Wagner; Mary Daly; Judy E Garber; Susan L Neuhausen; Peter Ainsworth; Hakan Olsson; Gareth Evans; Michael Osborne; Fergus J. Couch; William D Foulkes; Ellen Warner; Charmaine Kim-Sing; Olufunmilayo Olopade; Nadine Tung; Howard M Saal; Jeffrey N Weitzel; Sofia D Merajver; Marion Gauthier-Villars; Helena Jernstrom; Ping Sun; Jean-Sebastien Brunet
Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
Journal of the National Cancer Institute 2002;94(23):1773-9.
2002: Colleen S Sinclair; Camilo Adem; Ali Naderi; Cheryl L Soderberg; Michele Johnson; Kangjian Wu; Linda Wadum; Vicki L Couch; Thomas A Sellers; Daniel J Schaid; Jeffrey Slezak; Zachary S Fredericksen; James N Ingle; Lynn Hartmann; Robert B Jenkins; Fergus J. Couch
TBX2 is preferentially amplified in BRCA1- and BRCA2-related breast tumors.
Cancer research 2002;62(13):3587-91.
2002: Helen A Shih; Fergus J. Couch; Katherine L Nathanson; M Anne Blackwood; Timothy R Rebbeck; Katrina A Armstrong; Kathleen A Calzone; Jill Stopfer; Sheila Seal; Michael R Stratton; Barbara L Weber
BRCA1 and BRCA2 mutation frequency in women evaluated in a breast cancer risk evaluation clinic.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(4):994-9.
2002: Deborah Thompson; Csilla I Szabo; Jon Mangion; Rogier A Oldenburg; Fabrice Odefrey; Sheila Seal; Rita Barfoot; Karin Kroeze-Jansema; Dawn Teare; Nazneen Rahman; Hélène Renard; Graham Mann; John L Hopper; Saundra S Buys; Irene L Andrulis; Ruby Senie; Mary B Daly; Dee West; Elaine A Ostrander; Kenneth Offit; Tamar Peretz; Ana Osorio; J Benitez; Katherine L Nathanson; Olga M Sinilnikova; Edith Olàh; Yves-Jean Bignon; Pablo Ruiz; Michael D Badzioch; Hans Vasen; Andrew P Futreal; Catherine M Phelan; steven narod; Henry T Lynch; bruce ponder; Ros A Eeles; Hanne Meijers-Heijboer; Dominique Stoppa-Lyonnet; Fergus J. Couch; Diana M Eccles; D Gareth Evans; Jenny Chang-Claude; Gilbert Lenoir; Barbara L Weber; Peter Devilee; Douglas F Easton; David E Goldgar; Michael R Stratton
Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):827-31.
2002: Ali Naderi; Fergus J. Couch
BRCA2 and pancreatic cancer.
International journal of gastrointestinal cancer 2002;31(1-3):99-106.
2002: Fergus J. Couch
Is BRCA1 associated with familial breast cancer in India?
Cancer biology & therapy 2002;1(1):22-3.
2001: Lynn C Hartmann; Thomas A Sellers; Daniel J Schaid; T S Frank; Cheryl L Soderberg; DL Sitta; Marlene H Frost; Clive S Grant; John H Donohue; John E Woods; Shannon K McDonnell; Cate Walsh Vockley; Amie M Deffenbaugh; Fergus J. Couch; Robert B Jenkins
Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers.
Journal of the National Cancer Institute 2001;93(21):1633-7.
2001: Viji Shridhar; John Lee; Ajay Pandita; Stephen J Iturria; Rajeswari Avula; Julie Staub; M Morrissey; E Calhoun; A Sen; Kimberly R Kalli; Gary L Keeney; P Roche; William A Cliby; K Lu; Rosemarie Schmandt; Gordon B Mills; Robert C Bast; C David James; Fergus J. Couch; Lynn C Hartmann; Jim Lillie; David I Smith
Genetic analysis of early- versus late-stage ovarian tumors.
Cancer research 2001;61(15):5895-904.
2001: Guojun Wu ; Colleen S Sinclair; Shannon R Hinson; James N Ingle; Patrick C Roche; Fergus J. Couch
Structural analysis of the 17q22-23 amplicon identifies several independent targets of amplification in breast cancer cell lines and tumors.
Cancer research 2001;61(13):4951-5.
2001: Fergus J. Couch; James Cerhan; Robert A Vierkant; Dawn M Grabrick; Terry M Therneau; V Shane Pankratz; LC Hartmann; Janet E Olson; Celine M Vachon; Thomas A Sellers
Cigarette smoking increases risk for breast cancer in high-risk breast cancer families.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(4):327-32.
2001: DX Cai; C D James; Bernd W Scheithauer; Fergus J. Couch; Arie Perry
PS6K amplification characterizes a small subset of anaplastic meningiomas.
American journal of clinical pathology 2001;115(2):213-8.
2000: Kaili Wu; Shi-Wen (Albert) Jiang; Muthusamy Thangaraju; Guojun Wu ; Fergus J. Couch
Induction of the BRCA2 promoter by nuclear factor-kappa B.
The Journal of biological chemistry 2000;275(45):35548-56.
2000: Muthusamy Thangaraju; Scott H Kaufmann; Fergus J. Couch
BRCA1 facilitates stress-induced apoptosis in breast and ovarian cancer cell lines.
The Journal of biological chemistry 2000;275(43):33487-96.
2000: Dawn M Grabrick; LC Hartmann; James Cerhan; Robert A Vierkant; Terry M Therneau; Celine M Vachon; Janet E Olson; Fergus J. Couch; Kristin E Anderson; V Shane Pankratz; Thomas A Sellers
Risk of breast cancer with oral contraceptive use in women with a family history of breast cancer.
JAMA : the journal of the American Medical Association 2000;284(14):1791-8.
2000: Guojun Wu ; Colleen S Sinclair; J Paape; James N Ingle; Patrick C Roche; C David James; Fergus J. Couch
17q23 amplifications in breast cancer involve the PAT1, RAD51C, PS6K, and SIGma1B genes.
Cancer research 2000;60(19):5371-5.
2000: Lisa A Boardman; Mark Pittelkow; Fergus J. Couch; Daniel J Schaid; Shannon K McDonnell; Lawrence J Burgart; David A Ahlquist; J A Carney; D I Schwartz; Stephen N Thibodeau; L C Hartmann
Association of Peutz-Jeghers-like mucocutaneous pigmentation with breast and gynecologic carcinomas in women.
Medicine 2000;79(5):293-8.
2000: Colleen S Sinclair; R Berry; Daniel J Schaid; Stephen N Thibodeau; Fergus J. Couch
BRCA1 and BRCA2 have a limited role in familial prostate cancer.
Cancer research 2000;60(5):1371-5.
2000: Lisa A Boardman; Fergus J. Couch; Lawrence J Burgart; D Schwartz; R Berry; Shannon K McDonnell; Daniel J Schaid; L C Hartmann; JJ Schroeder; Constantine Straturis; Stephen N Thibodeau
Genetic heterogeneity in Peutz-Jeghers syndrome.
Human mutation 2000;16(1):23-30.
1999: Thomas A Sellers; R A King; James Cerhan; P L Chen; Dawn M Grabrick; Lawrence H Kushi; W S Oetting; Robert A Vierkant; Celine M Vachon; Fergus J. Couch; Terry M Therneau; Janet E Olson; V Shane Pankratz; LC Hartmann; V E Anderson
Fifty-year follow-up of cancer incidence in a historical cohort of Minnesota breast cancer families.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1999;8(12):1051-7.
1999: D I Schwartz; Noralane M Lindor; Catherine Walsh-Vockley; Patrick C Roche; M Mai; David I Smith; W Liu; Fergus J. Couch
p73 mutations are not detected in sporadic and hereditary breast cancer.
Breast cancer research and treatment 1999;58(1):25-9.
1999: L C Hartmann; T A Sellers; D J Schaid; S Nayfield; C S Grant; J A Bjoraker; J Woods; Fergus J. Couch
Clinical options for women at high risk for breast cancer.
The Surgical clinics of North America 1999;79(5):1189-206.
1999: Katherine L Nathanson; Danielle Antin-Ozerkis; Fergus J. Couch; Barbara L Weber
I1307K APC variant in non-Ashkenazi Jewish women affected with breast cancer.
American journal of medical genetics 1999;85(2):189-90.
1999: Fergus J. Couch; XY Wang; Guojun Wu ; Junqi Qian; Robert B Jenkins; C David James
Localization of PS6K to chromosomal region 17q23 and determination of its amplification in breast cancer.
Cancer research 1999;59(7):1408-11.
1999: B T Carroll; Fergus J. Couch; Timothy R Rebbeck; Barbara L Weber
Polymorphisms in PTEN in breast cancer families.
Journal of medical genetics 1999;36(2):94-6.
1998: J Chen; Daniel P Silver; Deepika Walpita; S B Cantor; A F Gazdar; Gail Tomlinson; Fergus J. Couch; B L Weber; Terry Ashley; David M Livingston; Ralph Scully
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
Molecular cell 1998;2(3):317-28.
1998: Fergus J. Couch; L C Hartmann
BRCA1 testing--advances and retreats.
JAMA : the journal of the American Medical Association 1998;279(12):955-7.
1998: Tone Ikdal Andersen; Hans Geir Eiken; Fergus J. Couch; G Kaada; Martina Skrede; Hilde Johnsen; T A Aloysius; Kjell Magne Tveit; L Tranebjaerg; Anne Dørum; Pål Møller; B L Weber; Anne-Lise Børresen-Dale
Constant denaturant gel electrophoresis (CDGE) in BRCA1 mutation screening.
Human mutation 1998;11(2):166-74.
1997: Fergus J. Couch; M L DeShano; M Anne Blackwood; Kathleen A Calzone; Jill Stopfer; L Campeau; Arupa Ganguly; Timothy R Rebbeck; Barbara L Weber
BRCA1 mutations in women attending clinics that evaluate the risk of breast cancer.
The New England journal of medicine 1997;336(20):1409-15.
1997: E Loh; Fergus J. Couch; C Hendricksen; L Farid; P F Kelly; Michael A Acker; John E Tomaszewski; S Bruce Malkowicz; Barbara L Weber
Development of donor-derived prostate cancer in a recipient following orthotopic heart transplantation.
JAMA : the journal of the American Medical Association 1997;277(2):133-7.
1997: Elizabeth M Rohlfs; W G Learning; Kenneth Friedman; Fergus J. Couch; Barbara L Weber; Lawrence M Silverman
Direct detection of mutations in the breast and ovarian cancer susceptibility gene BRCA1 by PCR-mediated site-directed mutagenesis.
Clinical chemistry 1997;43(1):24-9.
1997: S Thakur; H B Zhang; Y Peng; H Le; B Carroll; T Ward; J Yao; L M Farid; Fergus J. Couch; R B Wilson; Barbara L Weber
Localization of BRCA1 and a splice variant identifies the nuclear localization signal.
Molecular and cellular biology 1997;17(1):444-52.
1996: Patricia N Tonin; Barbara Weber; Kenneth Offit; Fergus J. Couch; Timothy R Rebbeck; Susan L Neuhausen; A K Godwin; Mary Daly; J Wagner-Costalos; D Berman; G Grana; E Fox; Michael F Kane; R D Kolodner; michael krainer; Daniel A Haber; Jeffery Struewing; Ellen Warner; B Rosen; Caryn Lerman; Beth N Peshkin; Larry Norton; OM Serova; William D Foulkes; Judy E Garber
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families.
Nature medicine 1996;2(11):1179-83.
1996: K J Abel; Lawrence C Brody; J M Valdes; Michael R Erdos; D R McKinley; Lucio H Castilla; Sofia D Merajver; Fergus J. Couch; L S Friedman; E A Ostermeyer; Eric D Lynch; Mary-Claire King; Piri Welcsh; S Osborne-Lawrence; M Spillman; Anne M Bowcock; Francis S Collins; Barbara L Weber
Characterization of EZH1, a human homolog of Drosophila Enhancer of zeste near BRCA1.
Genomics 1996;37(2):161-71.
1996: Timothy R Rebbeck; Fergus J. Couch; J Kant; Kathleen A Calzone; M DeShano; Y Peng; K Chen; Judy E Garber; Barbara L Weber
Genetic heterogeneity in hereditary breast cancer: role of BRCA1 and BRCA2.
American journal of human genetics 1996;59(3):547-53.
1996: Fergus J. Couch; Johanna M Rommens; Susan L Neuhausen; C Bélanger; M Dumont; K Abel; R Bell; S Berry; R Bogden; Lisa A Cannon-Albright; L Farid; Cynthia Frye; T Hattier; T Janecki; P Jiang; R Kehrer; J F Leblanc; J McArthur-Morrison; D Meney; Y Miki; Y Peng; C Samson; M Schroeder; S C Snyder; Jacques Simard
Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.
Genomics 1996;36(1):86-99.
1996: H Takahashi; H C Chiu; Christina A Bandera; K Behbakht; P C Liu; Fergus J. Couch; Barbara L Weber; Virginia A LiVolsi; M Furusato; B A Rebane; A Cardonick; I Benjamin; Mark A Morgan; SA King; J J Mikuta; Stephen C Rubin; J Boyd
Mutations of the BRCA2 gene in ovarian carcinomas.
Cancer research 1996;56(12):2738-41.
1996: Fergus J. Couch; L M Farid; M L DeShano; Sean V Tavtigian; Kathleen A Calzone; L Campeau; Y Peng; B Bogden; Q Chen; Susan L Neuhausen; D Shattuck-Eidens; A K Godwin; M Daly; D M Radford; S Sedlacek; Johanna M Rommens; Jacques Simard; Judy E Garber; Sofia D Merajver; Barbara L Weber
BRCA2 germline mutations in male breast cancer cases and breast cancer families.
Nature genetics 1996;13(1):123-5.
1996: Jason Simon; G Deshmukh; Fergus J. Couch; Sofia D Merajver; Barbara L Weber; Pascale Van Vooren; F Tissil; Josiane Szpirer; Claude Szpirer; Seth L Alper; Howard J Jacob; Frank C Brosius III
Chromosomal mapping of the rat Slc4a family of anion exchanger genes, Ae1, Ae2, and Ae3.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(5):380-2.
1996: Sean V Tavtigian; Jacques Simard; Johanna M Rommens; Fergus J. Couch; D Shattuck-Eidens; Susan L Neuhausen; Sofia D Merajver; Steinunn Thorlacius; Kenneth Offit; D Stoppa-Lyonnet; Carole Belanger; R Bell; S Berry; R Bogden; Q Chen; T Davis; M Dumont; Cynthia Frye; T Hattier; S Jammulapati; T Janecki; P Jiang; R Kehrer; J F Leblanc; J T Mitchell; J McArthur-Morrison; K Nguyen; Y Peng; C Samson; M Schroeder; S C Snyder; L Steele; M Stringfellow; C Stroup; B Swedlund; J Swense; David Teng; A Thomas; T Tran; M Tranchant; J Weaver-Feldhaus; AK Wong; H Shizuya; J E Eyfjord; Lisa A Cannon-Albright; M Tranchant; Fernand Labrie; Mark H Skolnick; B Weber; Alexander Kamb; David E Goldgar
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.
Nature genetics 1996;12(3):333-7.
1996: Susan L Neuhausen; Sylvie Mazoyer; L Friedman; Michael Stratton; Kenneth Offit; A Caligo; Gail Tomlinson; Lisa A Cannon-Albright; D Timothy Bishop; D Kelsell; E Solomon; B Weber; Fergus J. Couch; Jeffery Struewing; Patricia N Tonin; Francine Durocher; Steven A Narod; Mark H Skolnick; G Lenoir; OM Serova; Bruce A J Ponder; D Stoppa-Lyonnet; Douglas Easton; Mary-Claire King; David E Goldgar
Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.
American journal of human genetics 1996;58(2):271-80.
1996: Fergus J. Couch; Barbara L Weber
Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core.
Human mutation 1996;8(1):8-18.
1995: P P Ho; Fergus J. Couch; Lawrence C Brody; K J Abel; Michael Boehnke; T H Shearon; Settara C Chandrasekharappa; Francis S Collins; Barbara L Weber
Localization of the human homolog of the yeast cell division control 27 gene (CDC27) proximal to ITGB3 on human chromosome 17q21.3.
Somatic cell and molecular genetics 1995;21(5):351-5.
1995: H Takahashi; K Behbakht; P E McGovern; H C Chiu; Fergus J. Couch; Barbara L Weber; L S Friedman; Mary-Claire King; M Furusato; Virginia A LiVolsi
Mutation analysis of the BRCA1 gene in ovarian cancers.
Cancer research 1995;55(14):2998-3002.
1995: PJ Lynch; Fergus J. Couch; Ronald G Gregg; Patricia A Powers; K Hogan; Tommie V McCarthy
Mutation screening of dihydropyridine receptor gamma subunit cDNA from malignant hyperthermia susceptible patients.
Biochemical Society transactions 1995;23(2):352S.
1995: D Shattuck-Eidens; M McClure; Jacques Simard; Fernand Labrie; Steven A Narod; Fergus J. Couch; K Hoskins; B Weber; L Castilla; M Erdos
A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. Implications for presymptomatic testing and screening.
JAMA : the journal of the American Medical Association 1995;273(7):535-41.
1995: Fergus J. Couch; Judy E Garber; S Kiousis; Kathleen A Calzone; Elizabeth R Hauser; Sofia D Merajver; T S Frank; Michael Boehnke; Jeffrey S Chamberlain; Francis S Collins
Genetic analysis of eight breast-ovarian cancer families with suspected BRCA1 mutations.
Journal of the National Cancer Institute. Monographs 1995;(17):9-14.
1995: Fergus J. Couch; Lucio H Castilla; Jianfeng Xu; K J Abel; Piri Welcsh; S E King; L Wong; P P Ho; Sofia D Merajver; Lawrence C Brody
A YAC-, P1-, and cosmid-based physical map of the BRCA1 region on chromosome 17q21.
Genomics 1995;25(1):264-73.
1995: Lawrence C Brody; K J Abel; Lucio H Castilla; Fergus J. Couch; D R McKinley; G Yin; P P Ho; Sofia D Merajver; Settara C Chandrasekharappa; Jianfeng Xu
Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17.
Genomics 1995;25(1):238-47.
1995: Barbara L Weber; K J Abel; Fergus J. Couch; Sofia D Merajver; Lucio H Castilla; Lawrence C Brody; Francis S Collins
Transcript identification in the BRCA1 candidate region.
Breast cancer research and treatment 1995;33(2):115-24.
1994: Lucio H Castilla; Fergus J. Couch; Michael R Erdos; K F Hoskins; Kathleen A Calzone; Judy E Garber; J Boyd; M B Lubin; M L Deshano; Lawrence C Brody
Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.
Nature genetics 1994;8(4):387-91.
1994: Fergus J. Couch; S Kiousis; Lucio H Castilla; Jianfeng Xu; Settara C Chandrasekharappa; Jeffrey S Chamberlain; Francis S Collins; Barbara L Weber
Characterization of 10 new polymorphic dinucleotide repeats and generation of a high-density microsatellite-based physical map of the BRCA1 region of chromosome 17q21.
Genomics 1994;24(3):419-24.
1994: Barbara L Weber; K J Abel; Lawrence C Brody; W L Flejter; Settara C Chandrasekharappa; Fergus J. Couch; Sofia D Merajver; Francis S Collins
Familial breast cancer. Approaching the isolation of a susceptibility gene.
Cancer 1994;74(3 Suppl):1013-20.
1994: Fergus J. Couch; K J Abel; Lawrence C Brody; Michael Boehnke; Francis S Collins; Barbara L Weber
Localization of the gene for ATP citrate lyase (ACLY) distal to gastrin(GAS) and proximal to D17S856 on chromosome 17q12-q21.
Genomics 1994;21(2):444-6.
1994: Barbara L Weber; K J Abel; Fergus J. Couch; Sofia D Merajver; Settara C Chandrasekharappa; Lucio H Castilla; D McKinley; P P Ho; Kathleen A Calzone; T S Frank
Progress toward isolation of a breast cancer susceptibility gene, BRCA1.
Cold Spring Harbor symposia on quantitative biology 1994;59():531-6.
1993: Kathleen A Quane; J M Healy; K E Keating; B M Manning; Fergus J. Couch; Laura Palmucci; C Doriguzzi; TH Fagerlund; Kåre Berg; H Ording
Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia.
Nature genetics 1993;5(1):51-5.
1993: John C Mulley; H M Kozman; Hilary A Phillips; Agi K Gedeon; J A McCure; D E Iles; Ronald G Gregg; K Hogan; Fergus J. Couch; D H MacLennan
Refined genetic localization for central core disease.
American journal of human genetics 1993;52(2):398-405.
1993: Ronald G Gregg; Fergus J. Couch; K Hogan; Patricia A Powers
Assignment of the human gene for the alpha 1 subunit of the skeletal muscle DHP-sensitive Ca2+ channel (CACNL1A3) to chromosome 1q31-q32.
Genomics 1993;15(1):107-12.
1992: K Hogan; Fergus J. Couch; Patricia A Powers; Ronald G Gregg
A cysteine-for-arginine substitution (R614C) in the human skeletal muscle calcium release channel cosegregates with malignant hyperthermia.
Anesthesia and analgesia 1992;75(3):441-8.
1992: Fergus J. Couch; Tommie V McCarthy; K Hogan; Ronald G Gregg
Dinucleotide repeat polymorphism at the D10S179 locus.
Nucleic acids research 1992;20(6):1431.
1992: Fergus J. Couch; Ronald G Gregg; Tommie V McCarthy; K Hogan
Dinucleotide repeat polymorphism at the D10S178 locus.
Nucleic acids research 1992;20(6):1431.
1991: Fergus J. Couch; K Hogan; Tommie V McCarthy; Ronald G Gregg
Dinucleotide repeat polymorphism at the RYR1 locus (19q13.1).
Nucleic acids research 1991;19(18):5094.
1991: Fergus J. Couch; Tommie V McCarthy; Ronald G Gregg; K Hogan
Dinucleotide repeat polymorphism at the D8S161 locus.
Nucleic acids research 1991;19(18):5093.
1991: Fergus J. Couch; Tommie V McCarthy; Ronald G Gregg; K Hogan
Dinucleotide repeat polymorphism at the D17S518 locus.
Nucleic acids research 1991;19(18):5093.