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Akash Jain

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TOP 3
Akash Jain; Santanu Bhattacharya
Groove binding ligands for the interaction with parallel-stranded ps-duplex DNA and triplex DNA.
Santanu Bhattacharya; Padmaparna Chaudhuri; Akash Jain; Ananya Paul
Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
Akash Jain; Sharad K Gupta; Vibha Tandon
Evaluation of electronic effect of phenyl ring substituents on the DNA minor groove binding properties of novel bis and terbenzimidazoles: synthesis and spectroscopic studies of ligand-DNA interaction.

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All Publications

2010: Akash Jain; Santanu Bhattacharya
Groove binding ligands for the interaction with parallel-stranded ps-duplex DNA and triplex DNA.
Bioconjugate chemistry 2010;21(8):1389-403.
2010: Santanu Bhattacharya; Padmaparna Chaudhuri; Akash Jain; Ananya Paul
Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
Bioconjugate chemistry 2010;21(7):1148-59.
2009: Akash Jain; Sharad K Gupta; Vibha Tandon
Evaluation of electronic effect of phenyl ring substituents on the DNA minor groove binding properties of novel bis and terbenzimidazoles: synthesis and spectroscopic studies of ligand-DNA interaction.
Oligonucleotides 2009;19(4):329-40.
2009: Akash Jain; Vishnu Vardhan Reddy; Ananya Paul; Muniyappa K; Santanu Bhattacharya
Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1,3-phenylene-bis(piperazinyl benzimidazole) system.
Biochemistry 2009;48(45):10693-704.
2009: Akash Jain; Sharad K Gupta; Urmila Tawar; Sneh K Dogra; Vibha Tandon
Benzimidazoles: a minor groove-binding ligand-induced stabilization of triple helix.
Oligonucleotides 2009;19(1):53-62.
2006: Sulekh Chandra; Rajiv Kumar; Rajeev Singh; Akash Jain
Coordination stability between metal/ligands interaction by modern spectroscopic studies: IR, electronic, EPR and cyclic voltammetry of cobalt(II) complexes with organic skeleton containing cyclic ligands.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2006;65(3-4):852-8.
2006: Akash Jain; Satish Kumar Awasthi; Vibha Tandon
Triple helix stabilization by covalently linked DNA-bisbenzimidazole conjugate synthesized by maleimide-thiol coupling chemistry.
Bioorganic & medicinal chemistry 2006;14(18):6444-52.
2003: Urmila Tawar; Akash Jain; Ramesh Chandra; Yogendra Singh; Bilikere S Dwarakanath; N K Chaudhury; Liam Good; Vibha Tandon
Minor groove binding DNA ligands with expanded A/T sequence length recognition, selective binding to bent DNA regions and enhanced fluorescent properties.
Biochemistry 2003;42(45):13339-46.
2003: Urmila Tawar; Akash Jain; Bilikere S Dwarakanath; Ramesh Chandra; Yogendra Singh; N K Chaudhury; Divya Khaitan; Vibha Tandon
Influence of phenyl ring disubstitution on bisbenzimidazole and terbenzimidazole cytotoxicity: synthesis and biological evaluation as radioprotectors.
Journal of medicinal chemistry 2003;46(18):3785-92.