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C.M. Duijn

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N Amin; Yurii Aulchenko; Tatiana I Axenovich; E S Gusareva; Aaron Isaacs; A C J W Janssens; A V Kirichenko; Ben A Oostra; M Schuur; Irina V Zorkoltseva; C.M. Duijn
A genome-wide linkage study of individuals with high scores on NEO personality traits.
M Schuur; John C van Swieten; J M Vergeer-Drop; M M B Breteler; Albert Hofman; M Arfan Ikram; Aaron Isaacs; Ben A Oostra; C.M. Duijn
Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis.
A Demirkan; K Hek; Albert Hofman; Jouke-Jan Hottenga; A C J W Janssens; N Amin; Y S Aulchenko; Dorret I Boomsma; Eco J C De Geus; Willem A Nolen; Ben A Oostra; B W J H Penninx; P F Sullivan; H Tiemeier; A G Uitterlinden; C.M. Duijn; R van Dyck; Gonneke Willemsen; N R Wray; F G Zitman; Christel M Middeldorp
Genetic risk profiles for depression and anxiety in adult and elderly cohorts.

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All Publications

2012: N Amin; Yurii Aulchenko; Tatiana I Axenovich; E S Gusareva; Aaron Isaacs; A C J W Janssens; A V Kirichenko; Ben A Oostra; M Schuur; Irina V Zorkoltseva; C.M. Duijn
A genome-wide linkage study of individuals with high scores on NEO personality traits.
Molecular psychiatry 2012;17(10):1031-41.
2011: M Schuur; John C van Swieten; J M Vergeer-Drop; M M B Breteler; Albert Hofman; M Arfan Ikram; Aaron Isaacs; Ben A Oostra; C.M. Duijn
Cathepsin D gene and the risk of Alzheimer's disease: a population-based study and meta-analysis.
Neurobiology of aging 2011;32(9):1607-14.
2011: A Demirkan; K Hek; Albert Hofman; Jouke-Jan Hottenga; A C J W Janssens; N Amin; Y S Aulchenko; Dorret I Boomsma; Eco J C De Geus; Willem A Nolen; Ben A Oostra; B W J H Penninx; P F Sullivan; H Tiemeier; A G Uitterlinden; C.M. Duijn; R van Dyck; Gonneke Willemsen; N R Wray; F G Zitman; Christel M Middeldorp
Genetic risk profiles for depression and anxiety in adult and elderly cohorts.
Molecular psychiatry 2011;16(7):773-83.
2011: M van Hoek; T W van Herpt; Abbas Dehghan; Albert Hofman; A G Lieverse; C.M. Duijn; J C M Witteman; Eric J G Sijbrands
Association of an APOC3 promoter variant with type 2 diabetes risk and need for insulin treatment in lean persons.
Diabetologia 2011;54(6):1360-7.
2011: C E de Keyser; M Eijgelsheim; Albert Hofman; Eric J G Sijbrands; Anke Hilse Maitland-van der Zee; C.M. Duijn; André G Uitterlinden; J C M Witteman; B H Ch Stricker
Single nucleotide polymorphisms in genes that are associated with a modified response to statin therapy: the Rotterdam Study.
The pharmacogenomics journal 2011;11(1):72-80.
2011: M Schuur; John C van Swieten; S Schol-Gelok; M Arfan Ikram; Meike W Vernooij; Fan Liu; Aaron Isaacs; R de Boer; Inge de Koning; Wiro J Niessen; Henri A Vrooman; Ben A Oostra; Aad van Der Lugt; M M B Breteler; C.M. Duijn
Genetic risk factors for cerebral small-vessel disease in hypertensive patients from a genetically isolated population.
Journal of neurology, neurosurgery, and psychiatry 2011;82(1):41-4.
2011: D O Mook-Kanamori; L Ay; Albert Hofman; C.M. Duijn; Henriëtte A Moll; Hein Raat; A C S Hokken-Koelega; V W V Jaddoe
No association of obesity gene FTO with body composition at the age of 6 months. The Generation R Study.
Journal of endocrinological investigation 2011;34(1):16-20.
2010: M Schuur; Peter Henneman; John C van Swieten; M Carola Zillikens; Inge de Koning; A C J W Janssens; J C M Witteman; Yurii Aulchenko; Rune R Frants; Ben A Oostra; K Willems van Dijk; C.M. Duijn
Insulin-resistance and metabolic syndrome are related to executive function in women in a large family-based study.
European journal of epidemiology 2010;25(8):561-8.
2010: Peter Henneman; A C J W Janssens; M C Zillikens; Marijke Frolich; Rune R Frants; Ben A Oostra; C.M. Duijn; K Willems van Dijk
Menopause impacts the relation of plasma adiponectin levels with the metabolic syndrome.
Journal of internal medicine 2010;267(4):402-9.
2010: Anine H Stam; Boukje De Vries; A C J W Janssens; Kaate R J Vanmolkot; Yurii Aulchenko; Peter Henneman; Ben A Oostra; Rune R Frants; Arn van den Maagdenberg; Michel D Ferrari; C.M. Duijn; Gisela M Terwindt
Shared genetic factors in migraine and depression: evidence from a genetic isolate.
Neurology 2010;74(4):288-94.
2009: Inga Zerr; Kai Kallenberg; D M Summers; C Romero; A Taratuto; Uta Heinemann; M Breithaupt; Daniela Varges; Bettina Meissner; Anna Ladogana; M Schuur; S Haik; S J Collins; Gerard H Jansen; G B Stokin; J Pimentel; E Hewer; D Collie; P Smith; H Roberts; Jean-Philippe Brandel; C.M. Duijn; Maurizio Pocchiari; C Begue; Patrick cras; Robert G Will; P Sanchez-Juan
Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology 2009;132(Pt 10):2659-68.
2009: Karol Estrada; Michael Krawczak; Stefan Schreiber; Kate van Duijn; Lisette Stolk; Joyce B J van Meurs; Fan Liu; Brenda W J H Penninx; Jan H Smit; Nicole Vogelzangs; Jouke-Jan Hottenga; Gonneke Willemsen; Eco J C De Geus; Mattias Lorentzon; Huberta von Eller-Eberstein; Paul Lips; Natascha Schoor; Victor Pop; Jules de Keijzer; Albert Hofman; Yurii Aulchenko; Ben A Oostra; Claes Ohlsson; Dorret I Boomsma; André G Uitterlinden; C.M. Duijn; Fernando Rivadeneira; Manfred Kayser
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
Human molecular genetics 2009;18(18):3516-24.
2009: Tatiana I Axenovich; Irina V Zorkoltseva; N M Belonogova; M V Struchalin; A V Kirichenko; M Kayser; Ben A Oostra; C.M. Duijn; Yurii Aulchenko
Linkage analysis of adult height in a large pedigree from a Dutch genetically isolated population.
Human genetics 2009;126(3):457-71.
2009: Raluca Mihaescu; Mandy van Hoek; Eric J G Sijbrands; André G Uitterlinden; Jacqueline C M Witteman; Albert Hofman; C.M. Duijn; A Cecile J W Janssens
Evaluation of risk prediction updates from commercial genome-wide scans.
Genetics in medicine : official journal of the American College of Medical Genetics 2009;11(8):588-94.
2009: Emelia Benjamin; Kenneth M Rice; Dan E Arking; Arne Pfeufer; Charlotte van Noord; Albert Vernon Smith; Renate B Schnabel; Joshua C Bis; Eric Boerwinkle; Moritz F Sinner; Abbas Dehghan; Steven A Lubitz; Ralph B D'Agostino; Thomas Lumley; Georg Benedikt Ehret; Jan Heeringa; Thor Aspelund; Christopher Newton-Cheh; Martin G Larson; Kristin D Marciante; Elsayed Z Soliman; Fernando Rivadeneira; Thomas J Wang; Gudny Eiríksdottir; Daniel Levy; Bruce M Psaty; Man Li; Alanna M Chamberlain; Albert Hofman; Ramachandran S Vasan; Tamara B Harris; Jerome I Rotter; WEN KAO; Sunil K Agarwal; Bruno H Ch Stricker; Ke Wang; Lenore J Launer; Nicholas L Smith; Aravinda Chakravarti; André G Uitterlinden; Philip A Wolf; Nona Sotoodehnia; Anna Köttgen; C.M. Duijn; Thomas Meitinger; Martina Mueller; Siegfried Perz; Gerhard Steinbeck; H-Erich Wichmann; Kathryn L Lunetta; Susan R Heckbert; Vilmundur Gudnason; Alvaro Alonso; Stefan Kääb; Patrick T Ellinor; Jacqueline C M Witteman
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.
Nature genetics 2009;41(8):879-81.
2009: Diane B M A van Wieren-de Wijer; Anke Hilse Maitland-van der Zee; Anthonius de Boer; Abraham A Kroon; Peter W de Leeuw; Paul Schiffers; Rob G J H Janssen; Bruce M Psaty; C.M. Duijn; Bruno H Ch Stricker; Olaf Klungel
Reasons for non-response in observational pharmacogenetic research.
Pharmacoepidemiology and drug safety 2009;18(8):665-71.
2009: Yurii Aulchenko; Maksim V Struchalin; Nadezhda M Belonogova; Tatiana I Axenovich; Michael N Weedon; Albert Hofman; Andre G Uitterlinden; Manfred Kayser; Ben A Oostra; C.M. Duijn; A Cecile J W Janssens; Pavel M Borodin
Predicting human height by Victorian and genomic methods.
European journal of human genetics : EJHG 2009;17(8):1070-5.
2009: Antonia M W Coppus; Durk Fekkes; Willem M A Verhoeven; Heleen M Evenhuis; C.M. Duijn
Neopterin and the risk of dementia in persons with Down syndrome.
Neuroscience letters 2009;458(2):60-4.
2009: Andrew D Johnson; Maryam Kavousi; Albert Vernon Smith; Ming-Huei Chen; Abbas Dehghan; Thor Aspelund; Jing-Ping Lin; C.M. Duijn; Tamara B Harris; L Adrienne Cupples; Andre G Uitterlinden; Lenore Launer; Albert Hofman; Fernando Rivadeneira; Bruno Stricker; Qiong Yang; Christopher J O'Donnell; Vilmundur Gudnason; Jacqueline C Witteman
Genome-wide association meta-analysis for total serum bilirubin levels.
Human molecular genetics 2009;18(14):2700-10.
2009: Ramachandran S Vasan; Nicole L Glazer; Janine F Felix; Wolfgang Lieb; Philipp S Wild; Stephan B Felix; Norbert Watzinger; Martin G Larson; Nicholas L Smith; Abbas Dehghan; Anika Grosshennig; Arne Schillert; Alexander Teumer; Reinhold Schmidt; Sekar Kathiresan; Thomas Lumley; Yurii S Aulchenko; Inke R König; Tanja Zeller; Georg Homuth; Maksim Struchalin; Jayashri Aragam; Joshua C Bis; Fernando Rivadeneira; Jeanette Erdmann; Renate B Schnabel; Marcus Dörr; Robert Zweiker; Lars Lind; Richard J Rodeheffer; Karin Halina Greiser; Daniel Levy; Talin Haritunians; Jaap W Deckers; Jan Stritzke; Karl J Lackner; Uwe Völker; Erik Ingelsson; Iftikhar Kullo; Johannes Haerting; Christopher J O'Donnell; Susan R Heckbert; Bruno H Stricker; Andreas Ziegler; Thorsten Reffelmann; Margaret M Redfield; Karl Werdan; Gary F Mitchell; Kenneth Rice; Donna K Arnett; Albert Hofman; John S Gottdiener; Andre G Uitterlinden; Thomas Meitinger; Maria Blettner; Nele Friedrich; Thomas J Wang; Bruce M Psaty; C.M. Duijn; H-Erich Wichmann; Thomas F Munzel; Heyo K Kroemer; Emelia Benjamin; Jerome I Rotter; Jacqueline C Witteman; Heribert Schunkert; Helena Schmidt; Henry Völzke; Stefan Blankenberg
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.
JAMA : the journal of the American Medical Association 2009;302(2):168-78.
2009: Mark P S Sie; Aaron Isaacs; Moniek P M de Maat; Francesco U S Mattace-Raso; André G Uitterlinden; Isabella Kardys; Albert Hofman; Arnold P G Hoeks; Robert S Reneman; C.M. Duijn; Jaqueline C M Witteman
Genetic variation in the fibrinogen-alpha and fibrinogen-gamma genes in relation to arterial stiffness: the Rotterdam Study.
Journal of hypertension 2009;27(7):1392-8.
2009: Najaf Amin; Yurii Aulchenko; Marieke C Dekker; Robert F Ferdinand; Alwin van Spreeken; Alfons H Temmink; Frank C Verhulst; Ben A Oostra; C.M. Duijn
Suggestive linkage of ADHD to chromosome 18q22 in a young genetically isolated Dutch population.
European journal of human genetics : EJHG 2009;17(7):958-66.
2009: Nancy L Heard-Costa; M Carola Zillikens; Keri Monda; Asa Johansson; Tamara B Harris; Mao Fu; Talin Haritunians; Mary F Feitosa; Thor Aspelund; Gudny Eiriksdottir; Melissa Garcia; Lenore J Launer; Albert Vernon Smith; Braxton D Mitchell; Patrick F McArdle; Alan R Shuldiner; Suzette J Bielinski; Eric Boerwinkle; frederick brancati; Ellen W Demerath; James S Pankow; Alice M Arnold; Yii-Der Ida Chen; Nicole L Glazer; Barbara McKnight; Bruce M Psaty; Jerome I Rotter; Najaf Amin; Harry Campbell; Ulf Gyllensten; Cristian Pattaro; Peter P Pramstaller; Igor Rudan; Maksim Struchalin; Veronique Vitart; Xiaoyi Gao; Aldi Kraja; Michael A Province; Qunyuan Zhang; Larry D Atwood; Josée Dupuis; Joel N Hirschhorn; Cashell E Jaquish; Christopher J O'Donnell; Ramachandran S Vasan; Charles C White; Yurii S Aulchenko; Karol Estrada; Albert Hofman; Fernando Rivadeneira; André G Uitterlinden; Jacqueline C M Witteman; Ben A Oostra; Robert Kaplan; Vilmundur Gudnason; Jeffrey R O'Connell; Ingrid B Borecki; C.M. Duijn; L Adrienne Cupples; Caroline S Fox; Kari E North
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.
PLoS genetics 2009;5(6):e1000539.
2009: Cecilia M Lindgren; Iris M Heid; Joshua C Randall; Claudia Lamina; Valgerdur Steinthorsdottir; Lu Qi; Elizabeth K Speliotes; Gudmar Thorleifsson; Cristen J Willer; Blanca M Herrera; Anne U Jackson; Noha Lim; Paul Scheet; Nicole Soranzo; Najaf Amin; Yurii S Aulchenko; John C Chambers; Alexander Drong; Jian'an Luan; Helen N Lyon; Fernando Rivadeneira; Serena Sanna; Nicholas J Timpson; M Carola Zillikens; Jing Hua Zhao; Peter Almgren; Stefania Bandinelli; Amanda J Bennett; Richard N Bergman; Lori L Bonnycastle; Suzannah J Bumpstead; STEPHEN CHANOCK; Lynn Cherkas; Peter Chines; Lachlan Coin; Cyrus Cooper; Gabriel Crawford; Angela Doering; Anna Dominiczak; Alex S F Doney; Shah Ebrahim; Paul Elliott; Michael R Erdos; Karol Estrada; Luigi Ferrucci; Guido Fischer; Nita G Forouhi; Christian Gieger; Harald Grallert; Christopher J Groves; Scott Grundy; Candace Guiducci; David Hadley; Anders Hamsten; Aki S Havulinna; Albert Hofman; Rolf Holle; John W Holloway; Thomas Illig; Bo Isomaa; Leonie C Jacobs; Karen Jameson; Pekka Jousilahti; Fredrik Karpe; Johanna Kuusisto; Jaana Laitinen; G Mark Lathrop; Debbie A Lawlor; Massimo Mangino; Wendy L McArdle; Thomas Meitinger; Mario A Morken; Andrew P Morris; Patricia Munroe; Narisu Narisu; Anna Nordström; Peter Nordström; Ben A Oostra; Colin N A Palmer; Felicity Payne; John F Peden; Inga Prokopenko; Frida Renström; Aimo Ruokonen; Veikko Salomaa; Manjinder S Sandhu; Laura J Scott; ANGELO SCUTERI; Kaisa Silander; Kijoung Song; Xin Yuan; Heather M Stringham; Amy J Swift; Tiinamaija Tuomi; Manuela Uda; Peter Vollenweider; Gerard Waeber; Chris Wallace; Gudmundur Bragi Walters; Michael N Weedon; Jacqueline C M Witteman; Cuilin Zhang; Weihua Zhang; Mark J Caulfield; Francis S Collins; George Davey Smith; Ian N M Day; Paul W Franks; Andrew T Hattersley; Frank B Hu; Marjo-Riitta Jarvelin; Augustine Kong; Jaspal S Kooner; Markku Laakso; Edward Lakatta; Vincent Mooser; Andrew D Morris; Leena Peltonen; Nilesh J Samani; Timothy D Spector; David P Strachan; Toshiko Tanaka; Jaakko Tuomilehto; André G Uitterlinden; C.M. Duijn; Nicholas J Wareham; Dawn M Waterworth; Michael Boehnke; Panos Deloukas; Leif Groop; David J Hunter; Unnur Thorsteinsdottir; David Schlessinger; H-Erich Wichmann; Timothy M Frayling; Gonçalo R Abecasis; Joel N Hirschhorn; Ruth J F Loos; Kari Stefansson; Karen L Mohlke; Inês Barroso; Mark I McCarthy
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
PLoS genetics 2009;5(6):e1000508.
2009: Julian Little; Julian P T Higgins; John Ioannidis; David Moher; France Gagnon; Erik von Elm; Muin J Khoury; Barbara Cohen; George Davey Smith; Jeremy Grimshaw; Paul Scheet; Marta Gwinn; Robin E Williamson; Guang Yong Zou; Kim Hutchings; Candice Y Johnson; Valerie Tait; Miriam Wiens; Jean Golding; C.M. Duijn; John McLaughlin; Andrew Paterson; George Wells; Isabel Fortier; Matthew Freedman; Maja Zecevic; Richard King; Claire Infante-Rivard; Alexandre Stewart; Nicholas J Birkett
Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement.
Journal of clinical epidemiology 2009;62(6):597-608.e4.
2009: M Arfan Ikram; Fan Liu; Ben A Oostra; Albert Hofman; C.M. Duijn; Monique Breteler
The GAB2 gene and the risk of Alzheimer's disease: replication and meta-analysis.
Biological psychiatry 2009;65(11):995-9.
2009: Peter Henneman; Femke van der Sman-de Beer; Payman Hanifi Moghaddam; Petra Huijts; Anton F H Stalenhoef; John J P Kastelein; C.M. Duijn; Louis M Havekes; Rune R Frants; Ko Willems van Dijk; August Smelt
The expression of type III hyperlipoproteinemia: involvement of lipolysis genes.
European journal of human genetics : EJHG 2009;17(5):620-8.
2009: Emma De Feo; Roberto Persiani; Antonio La Greca; Rosarita Amore; Dario Arzani; Stefano Rausei; Domenico D'Ugo; Paolo Magistrelli; C.M. Duijn; Gualtiero Ricciardi; Stefania Boccia
A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression.
Mutation research 2009;675(1-2):60-5.
2009: M Arfan Ikram; Sudha Seshadri; Joshua C Bis; Myriam Fornage; Anita L DeStefano; Yurii S Aulchenko; Stephanie Debette; Thomas Lumley; Aaron R Folsom; Evita G van den Herik; Michiel J Bos; Alexa Beiser; Mary Cushman; Lenore J Launer; Eyal Shahar; Maksim Struchalin; Yangchun Du; Nicole L Glazer; Wayne D Rosamond; Fernando Rivadeneira; Margaret Kelly-Hayes; Oscar L Lopez; Josef Coresh; Albert Hofman; Charles DeCarli; Susan R Heckbert; Peter J Koudstaal; Qiong Yang; Nicholas L Smith; Carlos S Kase; Kenneth Rice; Talin Haritunians; Gerwin Roks; Paul L M de Kort; Kent D Taylor; Lonneke M de Lau; Ben A Oostra; Andre G Uitterlinden; Jerome I Rotter; Eric Boerwinkle; Bruce M Psaty; Thomas H Mosley; C.M. Duijn; Monique Breteler; W T Longstreth; Philip A Wolf
Genomewide association studies of stroke.
The New England journal of medicine 2009;360(17):1718-28.
2009: Claire Siemes; M Eijgelsheim; Jeanne P Dieleman; Ron van Schaik; André G Uitterlinden; C.M. Duijn; Albert Hofman; J W W Coebergh; B H Ch Stricker; Loes E Visser
No modification of the beneficial effect of NSAIDs on colorectal cancer by CYP2C9 genotype.
The Netherlands journal of medicine 2009;67(4):134-41.
2009: Julian Little; Julian P T Higgins; John Ioannidis; David Moher; France Gagnon; Erik von Elm; Muin J Khoury; Barbara Cohen; George Davey Smith; Jeremy Grimshaw; Paul Scheet; Marta Gwinn; Robin E Williamson; Guang Yong Zou; Kim Hutchings; Candice Y Johnson; Valerie Tait; Miriam Wiens; Jean Golding; C.M. Duijn; John McLaughlin; Andrew Paterson; George Wells; Isabel Fortier; Matthew Freedman; Maja Zecevic; Richard King; Claire Infante-Rivard; Alexandre Stewart; Nicholas J Birkett
STrengthening the REporting of Genetic Association studies (STREGA)--an extension of the STROBE statement.
European journal of clinical investigation 2009;39(4):247-66.
2009: Dennis O Mook-Kanamori; Eric A P Steegers; Andre G Uitterlinden; Henriëtte A Moll; C.M. Duijn; Albert Hofman; Vincent W V Jaddoe
Breast-feeding modifies the association of PPARgamma2 polymorphism Pro12Ala with growth in early life: the Generation R Study.
Diabetes 2009;58(4):992-8.
2009: Jasper J Brugts; Moniek P M de Maat; eric boersma; J C M Witteman; C.M. Duijn; André G Uitterlinden; Michel Bertrand; Willem J Remme; Alistair Hall; Roberto Ferrari; Alexander Hessel Jan Danser; Maarten L Simoons
The rationale and design of the PERindopril GENEtic association study (PERGENE): a pharmacogenetic analysis of angiotensin-converting enzyme inhibitor therapy in patients with stable coronary artery disease.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2009;23(2):171-81.
2009: Samuli Ripatti; Tim Becker; Heike Bickeböller; Annica Dominicus; Christine Fischer; Keith Humphreys; Gudrun Jonasdottir; Yves Moreau; Marita Olsson; Alexander Ploner; Nuala Sheehan; Kristel Van Steen; Max Baur; C.M. Duijn; Juni Palmgren
GENESTAT: an information portal for design and analysis of genetic association studies.
European journal of human genetics : EJHG 2009;17(4):533-6.
2009: M Carola Zillikens; Joyce B J van Meurs; Eric J G Sijbrands; Fernando Rivadeneira; Abbas Dehghan; Johannes P T M van Leeuwen; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman; André G Uitterlinden; Huibert A P Pols
SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin.
Free radical biology & medicine 2009;46(6):836-41.
2009: A Cecile J W Janssens; Angela M González-Zuloeta Ladd; Sandra López-Léon; John Ioannidis; Ben A Oostra; Muin J Khoury; C.M. Duijn
An empirical comparison of meta-analyses of published gene-disease associations versus consortium analyses.
Genetics in medicine : official journal of the American College of Medical Genetics 2009;11(3):153-62.
2009: Jacqueline M Vink; August B Smit; Eco J C De Geus; Patrick F Sullivan; Gonneke Willemsen; Jouke-Jan Hottenga; Johannes H Smit; Witte J G Hoogendijk; Frans G Zitman; Leena Peltonen; Jaakko Kaprio; Nancy L Pedersen; Patrik K E Magnusson; Tim D Spector; Kirsten Ohm Kyvik; Katherine I Morley; Andrew C Heath; Nicholas G Martin; Rudi G J Westendorp; P Eline Slagboom; Henning Tiemeier; Albert Hofman; André G Uitterlinden; Yurii S Aulchenko; Najaf Amin; C.M. Duijn; Brenda W Penninx; Dorret I Boomsma
Genome-wide association study of smoking initiation and current smoking.
American journal of human genetics 2009;84(3):367-79.
2009: Julian Little; Julian P T Higgins; John Ioannidis; David Moher; France Gagnon; Erik von Elm; Muin J Khoury; Barbara Cohen; George Davey Smith; Jeremy Grimshaw; Paul Scheet; Marta Gwinn; Robin E Williamson; Guang Yong Zou; Kim Hutchings; Candice Y Johnson; Valerie Tait; Miriam Wiens; Jean Golding; C.M. Duijn; John McLaughlin; Andrew Paterson; George Wells; Isabel Fortier; Matthew Freedman; Maja Zecevic; Richard King; Claire Infante-Rivard; Alexandre Stewart; Nicholas J Birkett
Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement.
Human genetics 2009;125(2):131-51.
2009: Dominiek D G Despriet; C.M. Duijn; Ben A Oostra; André G Uitterlinden; Albert Hofman; Alan F Wright; Jacoline B ten Brink; Arne Bakker; Paulus T V M de Jong; Johannes Vingerling; Arthur A B Bergen; Caroline C W Klaver
Complement component C3 and risk of age-related macular degeneration.
Ophthalmology 2009;116(3):474-480.e2.
2009: Julian Little; Julian P T Higgins; John Ioannidis; David Moher; France Gagnon; Erik von Elm; Muin J Khoury; Barbara Cohen; George Davey Smith; Jeremy Grimshaw; Paul Scheet; Marta Gwinn; Robin E Williamson; Guang Yong Zou; Kim Hutchings; Candice Y Johnson; Valerie Tait; Miriam Wiens; Jean Golding; C.M. Duijn; John McLaughlin; Andrew Paterson; George Wells; Isabel Fortier; Matthew Freedman; Maja Zecevic; Richard King; Claire Infante-Rivard; Alexandre Stewart; Nick Birkett
STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement.
PLoS medicine 2009;6(2):e22.
2009: Julian Little; Julian P T Higgins; John Ioannidis; David Moher; France Gagnon; Erik von Elm; Muin J Khoury; Barbara Cohen; George Davey Smith; Jeremy Grimshaw; Paul Scheet; Marta Gwinn; Robin E Williamson; Guang Yong Zou; Kim Hutchings; Candice Y Johnson; Valerie Tait; Miriam Wiens; Jean Golding; C.M. Duijn; John McLaughlin; Andrew Paterson; George Wells; Isabel Fortier; Matthew Freedman; Maja Zecevic; Richard King; Claire Infante-Rivard; Alexandre Stewart; Nicholas J Birkett
STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement.
Annals of internal medicine 2009;150(3):206-15.
2009: A L Berends; M C Zillikens; Christianne J M De Groot; Fernando Rivadeneira; Ben A Oostra; C.M. Duijn; E A P Steegers
Body composition by dual-energy X-ray absorptiometry in women with previous pre-eclampsia or small-for-gestational-age offspring.
BJOG : an international journal of obstetrics and gynaecology 2009;116(3):442-51.
2009: Wing Chi Choy; Sandra López León; Yurii Aulchenko; Johan P Mackenbach; Ben A Oostra; C.M. Duijn; A Cecile J W Janssens
Role of shared genetic and environmental factors in symptoms of depression and body composition.
Psychiatric genetics 2009;19(1):32-8.
2009: Behrooz Alizadeh; Omer T Njajou; M R Millán; Albert Hofman; Monique Breteler; C.M. Duijn
HFE variants, APOE and Alzheimer's disease: findings from the population-based Rotterdam study.
Neurobiology of aging 2009;30(2):330-2.
2009: Asa Johansson; Fabio Marroni; Caroline Hayward; Christopher S Franklin; Anatoly V Kirichenko; Inger Jonasson; Andrew A Hicks; Veronique Vitart; Aaron Isaacs; Tatiana Axenovich; Susan Campbell; Malcolm G Dunlop; Jamie Floyd; Nick Hastie; Albert Hofman; Sara Knott; Ivana Kolcic; Irene Pichler; Ozren Polasek; Fernando Rivadeneira; Albert Tenesa; André G Uitterlinden; Sarah H Wild; Irina V Zorkoltseva; Thomas Meitinger; James Wilson; Igor Rudan; Harry Campbell; Cristian Pattaro; Peter Pramstaller; Ben A Oostra; Alan F Wright; C.M. Duijn; Yurii S Aulchenko; Ulf Gyllensten
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis.
Human molecular genetics 2009;18(2):373-80.
2009: Mark Eijgelsheim; Adrianus L H J Aarnoudse; Fernando Rivadeneira; Jan A Kors; Jacqueline C M Witteman; Albert Hofman; C.M. Duijn; André G Uitterlinden; Bruno H C Stricker
Identification of a common variant at the NOS1AP locus strongly associated to QT-interval duration.
Human molecular genetics 2009;18(2):347-57.
2009: Stefania Boccia; Paolo Boffetta; Paul Brennan; Gualtiero Ricciardi; Francesco Gianfagna; Keitaro Matsuo; C.M. Duijn; Rayjean J Hung
Meta-analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and risk of head and neck and lung cancer.
Cancer letters 2009;273(1):55-61.
2009: Casper Jansen; Maaike Schuur; W G M Spliet; Willem A van Gool; C.M. Duijn; Annemieke J M Rozemuller
[Eleven years of autopsy on account of Creutzfeldt-Jakob disease in the Netherlands].
Nederlands tijdschrift voor geneeskunde 2009;153():A172.
2009: Maaike Schuur; Casper Jansen; Annemieke J M Rozemuller; Willem A van Gool; C.M. Duijn
[Human spongiform encephalopathies in the Netherlands].
Nederlands tijdschrift voor geneeskunde 2009;153():A173.
2009: D B M A van Wieren-de Wijer; Anke Hilse Maitland-van der Zee; Anthonius de Boer; Svetlana V Belitser; Abraham A Kroon; Peter W de Leeuw; P Schiffers; Rob G J H Janssen; C.M. Duijn; B H C H Stricker; Olaf Klungel
Determinants of DNA yield and purity collected with buccal cell samples.
European journal of epidemiology 2009;24(11):677-82.
2009: Dennis O Mook-Kanamori; Sandra W K de Kort; C.M. Duijn; Andre G Uitterlinden; Albert Hofman; Henriëtte A Moll; Eric A P Steegers; Anita C S Hokken-Koelega; Vincent W V Jaddoe
Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies.
BMC medical genetics 2009;10():67.
2009: Sandra López León; Wing Chi Choy; Yurii Aulchenko; Stephan J Claes; Ben A Oostra; Johan P Mackenbach; C.M. Duijn; A Cecile J W Janssens
Genetic factors influence the clustering of depression among individuals with lower socioeconomic status.
PloS one 2009;4(3):e5069.
2009: Maryam Omidvar; Lisette Stolk; André G Uitterlinden; Albert Hofman; C.M. Duijn; Henning Tiemeier
The effect of catechol-O-methyltransferase Met/Val functional polymorphism on smoking cessation: retrospective and prospective analyses in a cohort study.
Pharmacogenetics and genomics 2009;19(1):45-51.
2009: Diane B M A van Wieren-de Wijer; Anke Hilse Maitland-van der Zee; Anthonius de Boer; Abraham A Kroon; Peter W de Leeuw; Paul Schiffers; Rob G J H Janssen; Bruce M Psaty; C.M. Duijn; Bruno H Ch Stricker; Olaf Klungel
Interaction between the Gly460Trp alpha-adducin gene variant and diuretics on the risk of myocardial infarction.
Journal of hypertension 2009;27(1):61-8.
2009: Stefania Boccia; Mia Hashibe; Paola Gallì; Emma De Feo; Takahiro Asakage; Tomoko Hashimoto; Akio Hiraki; Takahiko Katoh; Takeshi Nomura; Akira Yokoyama; C.M. Duijn; Gualtiero Ricciardi; Paolo Boffetta
Aldehyde dehydrogenase 2 and head and neck cancer: a meta-analysis implementing a Mendelian randomization approach.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(1):248-54.
2009: Cristen J Willer; Elizabeth K Speliotes; Ruth J F Loos; Shengxu Li; Cecilia M Lindgren; Iris M Heid; Sonja I Berndt; Amanda Elliott; Anne U Jackson; Claudia Lamina; Guillaume Lettre; Noha Lim; Helen N Lyon; Steven A McCarroll; Konstantinos Papadakis; Lu Qi; Joshua C Randall; Rosa Maria Roccasecca; Serena Sanna; Paul Scheet; Michael N Weedon; Eleanor Wheeler; Jing Hua Zhao; Leonie C Jacobs; Inga Prokopenko; Nicole Soranzo; Toshiko Tanaka; Nicholas J Timpson; Peter Almgren; Amanda Bennett; Richard N Bergman; Sheila A Bingham; Lori L Bonnycastle; Morris Brown; Noël P Burtt; Peter Chines; Lachlan Coin; Francis S Collins; John M Connell; Cyrus Cooper; George Davey Smith; Elaine M Dennison; Parimal Deodhar; Paul Elliott; Michael R Erdos; Karol Estrada; David M Evans; Lauren Gianniny; Christian Gieger; Christopher J Gillson; Candace Guiducci; Rachel Hackett; David Hadley; Alistair Hall; Aki S Havulinna; Johannes Hebebrand; Albert Hofman; Bo Isomaa; Kevin B Jacobs; Toby Johnson; Pekka Jousilahti; Zorica Jovanovic; Kay-Tee Khaw; Peter Kraft; Mikko Kuokkanen; Johanna Kuusisto; Jaana Laitinen; Edward G Lakatta; Jian'an Luan; Robert N Luben; Massimo Mangino; Wendy L McArdle; Thomas Meitinger; Antonella Mulas; Patricia B Munroe; Narisu Narisu; Andrew R Ness; Kate Northstone; Stephen O'Rahilly; Carolin Purmann; Matthew G Rees; Martin Ridderstråle; Susan M Ring; Fernando Rivadeneira; Aimo Ruokonen; Manjinder S Sandhu; Jouko Saramies; Laura J Scott; ANGELO SCUTERI; Kaisa Silander; Matthew A Sims; Kijoung Song; Jonathan Stephens; Suzanne Stevens; Heather M Stringham; Y C Loraine Tung; Timo T Valle; C.M. Duijn; Karani S Vimaleswaran; Peter Vollenweider; Gerard Waeber; chris wallace; Richard M Watanabe; Dawn M Waterworth; Nicholas Watkins; Jacqueline C M Witteman; Eleftheria Zeggini; Guangju Zhai; M Carola Zillikens; David Altshuler; Mark J Caulfield; STEPHEN CHANOCK; I Sadaf Farooqi; Luigi Ferrucci; Jack M Guralnik; Andrew T Hattersley; Frank B Hu; Marjo-Riitta Jarvelin; Markku Laakso; Vincent Mooser; Ken K Ong; Willem H Ouwehand; Veikko Salomaa; Nilesh J Samani; Timothy D Spector; Tiinamaija Tuomi; Jaakko Tuomilehto; Manuela Uda; André G Uitterlinden; Nicholas J Wareham; Panagiotis Deloukas; Timothy M Frayling; Leif C Groop; Richard Hayes; David J Hunter; Karen L Mohlke; Leena Peltonen; David Schlessinger; David P Strachan; H-Erich Wichmann; Mark I McCarthy; Michael Boehnke; Inês Barroso; Gonçalo R Abecasis; Joel N Hirschhorn
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.
Nature genetics 2009;41(1):25-34.
2009: Yurii S Aulchenko; Samuli Ripatti; Ida Lindqvist; Dorret Boomsma; Iris M Heid; Peter P Pramstaller; Brenda W J H Penninx; A Cecile J W Janssens; James Wilson; Tim Spector; Nicholas G Martin; Nancy L Pedersen; Kirsten Ohm Kyvik; Jaakko Kaprio; Albert Hofman; Nelson B Freimer; Marjo-Riitta Jarvelin; Ulf Gyllensten; Harry Campbell; Igor Rudan; Asa Johansson; Fabio Marroni; Caroline Hayward; Veronique Vitart; Inger Jonasson; Cristian Pattaro; Alan Wright; Nick Hastie; Irene Pichler; Andrew A Hicks; Mario Falchi; Gonneke Willemsen; Jouke-Jan Hottenga; Eco J C de Geus; Grant W Montgomery; John Whitfield; Patrik Magnusson; Juha Saharinen; Markus Perola; Kaisa Silander; Aaron Isaacs; Eric J G Sijbrands; Andre G Uitterlinden; Jacqueline C M Witteman; Ben A Oostra; Paul Elliott; Aimo Ruokonen; Chiara Sabatti; Christian Gieger; Thomas Meitinger; Florian Kronenberg; Angela Döring; H-Erich Wichmann; Johannes H Smit; Mark I McCarthy; C.M. Duijn; Leena Peltonen
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
Nature genetics 2009;41(1):47-55.
2009: Inga Prokopenko; Claudia Langenberg; Jose C Florez; Richa Saxena; Nicole Soranzo; Gudmar Thorleifsson; Ruth J F Loos; Alisa K Manning; Anne U Jackson; Yurii Aulchenko; Simon C Potter; Michael R Erdos; Serena Sanna; Jouke-Jan Hottenga; Eleanor Wheeler; Marika Kaakinen; Valeriya Lyssenko; Wei-Min Chen; Kourosh Ahmadi; Jacques Beckmann; Richard N Bergman; Murielle Bochud; Lori L Bonnycastle; Thomas A Buchanan; Antonio Cao; Alessandra Cervino; Lachlan Coin; Francis S Collins; Laura Crisponi; Eco J C de Geus; Abbas Dehghan; Panos Deloukas; Alex S F Doney; Paul Elliott; Nelson Freimer; Vesela Gateva; Christian Herder; Albert Hofman; Thomas E Hughes; Sarah Hunt; Thomas Illig; Michael Inouye; Bo Isomaa; Toby Johnson; Augustine Kong; Maria Krestyaninova; Johanna Kuusisto; Markku Laakso; Noha Lim; Ulf Lindblad; Cecilia M Lindgren; Owen T McCann; Karen L Mohlke; Andrew D Morris; Silvia Naitza; Marco Orrù; Colin N A Palmer; Anneli Pouta; Joshua Randall; Wolfgang Rathmann; Jouko Saramies; Paul Scheet; Laura J Scott; ANGELO SCUTERI; Stephen Sharp; Eric Sijbrands; Jan H Smit; Kijoung Song; Valgerdur Steinthorsdottir; Heather M Stringham; Tiinamaija Tuomi; Jaakko Tuomilehto; André G Uitterlinden; Benjamin F Voight; Dawn Waterworth; H-Erich Wichmann; Gonneke Willemsen; Jacqueline C M Witteman; Xin Yuan; Jing Hua Zhao; Eleftheria Zeggini; David Schlessinger; Manjinder Sandhu; dorret boomsma; Manuela Uda; Tim D Spector; Brenda Wjh Penninx; David Altshuler; Peter Vollenweider; Marjo Riitta Jarvelin; Edward Lakatta; Gerard Waeber; Caroline S Fox; Leena Peltonen; Leif C Groop; Vincent Mooser; L Adrienne Cupples; Unnur Thorsteinsdottir; Michael Boehnke; Inês Barroso; C.M. Duijn; Josée Dupuis; Richard M Watanabe; Kari Stefansson; Mark I McCarthy; Nicholas J Wareham; James B Meigs; Gonçalo R Abecasis
Variants in MTNR1B influence fasting glucose levels.
Nature genetics 2009;41(1):77-81.
2009: Liesbeth Duijts; Liesbeth E Bakker-Jonges; Dennis O Mook-Kanamori; Joost A M Labout; Albert Hofman; C.M. Duijn; Jacques J M van Dongen; Herbert Hooijkaas; Henriëtte A Moll; Vincent W V Jaddoe
Variation in the IGF-1 gene is associated with lymphocyte subset counts in neonates: the Generation R Study.
Clinical endocrinology 2009;70(1):53-9.
2008: Abbas Dehghan; Anna Köttgen; Qiong Yang; Shih-Jen Hwang; WEN KAO; Fernando Rivadeneira; Eric Boerwinkle; Daniel Levy; Albert Hofman; Brad C Astor; Emelia Benjamin; C.M. Duijn; Jacqueline C Witteman; Josef Coresh; Caroline S Fox
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.
Lancet 2008;372(9654):1953-61.
2008: Antonia M W Coppus; Heleen M Evenhuis; Gert-Jan Verberne; Frank E Visser; Ben A Oostra; Piet Eikelenboom; Willem A van Gool; A Cecile J W Janssens; C.M. Duijn
Survival in elderly persons with Down syndrome.
Journal of the American Geriatrics Society 2008;56(12):2311-6.
2008: Kaya Bilguvar; Katsuhito Yasuno; Mika Niemelä; Ynte M Ruigrok; Mikael von Und Zu Fraunberg; C.M. Duijn; Leonard H van den Berg; Shrikant M Mane; Christopher E Mason; Murim Choi; Emília Gaál; Yasar Bayri; Luis Kolb; Zulfikar Arlier; Sudhakar Ravuri; Antti Ronkainen; Atsushi Tajima; Aki Laakso; Akira Hata; Hidetoshi Kasuya; Timo Koivisto; Jaakko Rinne; Juha Ohman; Monique Breteler; cisca wijmenga; Sate Matthew; Gabriel J E Rinkel; Juha Hernesniemi; Juha E Jääskeläinen; Aarno Palotie; Ituro Inoue; Richard P Lifton; Murat Günel
Susceptibility loci for intracranial aneurysm in European and Japanese populations.
Nature genetics 2008;40(12):1472-7.
2008: Yurii Aulchenko; Ilse A Hoppenbrouwers; Sreeram V Ramagopalan; Linda Broer; Naghmeh Jafari; Jan Hillert; Jenny Link; Wangko Lundström; Eva Greiner; A Dessa Sadovnick; Dirk Goossens; Christine Van Broeckhoven; Jurgen Del-Favero; George C Ebers; Ben A Oostra; C.M. Duijn; Rogier Q Hintzen
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.
Nature genetics 2008;40(12):1402-3.
2008: M Carola Zillikens; Mojgan Yazdanpanah; L M Pardo; Fernando Rivadeneira; Yurii Aulchenko; Ben A Oostra; André G Uitterlinden; H A P Pols; C.M. Duijn
Sex-specific genetic effects influence variation in body composition.
Diabetologia 2008;51(12):2233-41.
2008: Anne L Berends; Eric A Steegers; Aaron Isaacs; Y S Aulchenko; Fan Liu; Christianne J de Groot; Ben A Oostra; C.M. Duijn
Familial aggregation of preeclampsia and intrauterine growth restriction in a genetically isolated population in The Netherlands.
European journal of human genetics : EJHG 2008;16(12):1437-42.
2008: Hedi Schelleman; Olaf Klungel; J C M Witteman; Monique Breteler; Albert Hofman; C.M. Duijn; Anthonius de Boer; B H Ch Stricker
Interaction between polymorphisms in the renin-angiotensin-system and angiotensin-converting enzyme inhibitor or beta-blocker use and the risk of myocardial infarction and stroke.
The pharmacogenomics journal 2008;8(6):400-7.
2008: Sharmila S Boekhoorn; Aaron Isaacs; André G Uitterlinden; C.M. Duijn; Albert Hofman; Paulus T V M de Jong; Johannes Vingerling
Polymorphisms in the vascular endothelial growth factor gene and risk of age-related macular degeneration: the Rotterdam Study.
Ophthalmology 2008;115(11):1899-903.
2008: Mandy van Hoek; Abbas Dehghan; Jacqueline C M Witteman; C.M. Duijn; André G Uitterlinden; Ben A Oostra; Albert Hofman; Eric J G Sijbrands; A Cecile J W Janssens
Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.
Diabetes 2008;57(11):3122-8.
2008: Lintje Ho; Sharmila S Boekhoorn; C.M. Duijn; André G Uitterlinden; Albert Hofman; Paulus T V M de Jong; Theo Stijnen; Johannes Vingerling
Cataract surgery and the risk of aging macula disorder: the rotterdam study.
Investigative ophthalmology & visual science 2008;49(11):4795-800.
2008: A Cecile J W Janssens; C.M. Duijn
Genome-based prediction of common diseases: advances and prospects.
Human molecular genetics 2008;17(R2):R166-73.
2008: Francesco Gianfagna; Emma De Feo; C.M. Duijn; Gualtiero Ricciardi; Stefania Boccia
A systematic review of meta-analyses on gene polymorphisms and gastric cancer risk.
Current genomics 2008;9(6):361-74.
2008: Peter Henneman; Yurii Aulchenko; Rune R Frants; Ko Willems van Dijk; Ben A Oostra; C.M. Duijn
Prevalence and heritability of the metabolic syndrome and its individual components in a Dutch isolate: the Erasmus Rucphen Family study.
Journal of medical genetics 2008;45(9):572-7.
2008: Vera A A van Houten; Dennis O Mook-Kanamori; Lennie van Osch-Gevers; Eric A P Steegers; Albert Hofman; Henriëtte A Moll; C.M. Duijn; Willem A Helbing; Anita C S Hokken-Koelega; Vincent W V Jaddoe
A variant of the IGF-I gene is associated with blood pressure but not with left heart dimensions at the age of 2 years: the Generation R Study.
European journal of endocrinology / European Federation of Endocrine Societies 2008;159(3):209-16.
2008: Sandra López León; A Cecile J W Janssens; Henning Tiemeier; Albert Hofman; Yurii Aulchenko; Pieter J L M Snijders; Stephan Claes; Ben A Oostra; C.M. Duijn
Angiotensinogen M235T polymorphism and symptoms of depression in a population-based study and a family-based study.
Psychiatric genetics 2008;18(4):162-6.
2008: Sandra López León; A Cecile J W Janssens; Angela M González-Zuloeta Ladd; J Del-Favero; S J Claes; Ben A Oostra; C.M. Duijn
Meta-analyses of genetic studies on major depressive disorder.
Molecular psychiatry 2008;13(8):772-85.
2008: Bas J M Peters; Anke Hilse Maitland-van der Zee; Bruno H Ch Stricker; Diane B M A van Wieren-de Wijer; Anthonius de Boer; Abraham A Kroon; Peter W de Leeuw; Paul Schiffers; Rob G J H Janssen; C.M. Duijn; Olaf Klungel
Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant.
Pharmacogenetics and genomics 2008;18(7):631-6.
2008: Fan Liu; Anatoliy Kirichenko; Tatiana I Axenovich; C.M. Duijn; Yurii Aulchenko
An approach for cutting large and complex pedigrees for linkage analysis.
European journal of human genetics : EJHG 2008;16(7):854-60.
2008: A Cecile J W Janssens; C.M. Duijn
Five genetic variants associated with prostate cancer.
The New England journal of medicine 2008;358(25):2739; author reply 2741.
2008: Ingrid Meulenbelt; Josine L Min; Steffan Bos; Naghmeh Riyazi; Jeanine J Houwing-Duistermaat; Henk-Jan van der Wijk; Herman M Kroon; Masahiro Nakajima; Shiro Ikegawa; André G Uitterlinden; Joyce B J van Meurs; Wendy M van der Deure; Theo J Visser; Albert B Seymour; Nico Lakenberg; Ruud van der Breggen; Dennis Kremer; C.M. Duijn; Margreet Kloppenburg; John Loughlin; P Eline Slagboom
Identification of DIO2 as a new susceptibility locus for symptomatic osteoarthritis.
Human molecular genetics 2008;17(12):1867-75.
2008: Lydi M J W van Driel; Anna C Verkleij-Hagoort; Robert de Jonge; André G Uitterlinden; Eric A P Steegers; C.M. Duijn; Régine P M Steegers-Theunissen
Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs.
Birth defects research. Part A, Clinical and molecular teratology 2008;82(6):474-81.
2008: Lydi M J W van Driel; Huberdina P M Smedts; Willem A Helbing; Aaron Isaacs; Jan Lindemans; André G Uitterlinden; C.M. Duijn; Jeanne H M de Vries; Eric A P Steegers; Régine P M Steegers-Theunissen
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
European heart journal 2008;29(11):1424-31.
2008: I A Hoppenbrouwers; Yurii Aulchenko; G C Ebers; S V Ramagopalan; B A Oostra; C.M. Duijn; R Q Hintzen
EVI5 is a risk gene for multiple sclerosis.
Genes and immunity 2008;9(4):334-7.
2008: A M W Coppus; Heleen M Evenhuis; G-J Verberne; F E Visser; A Arias-Vasquez; Fakhredin A Sayed-Tabatabaei; J Vergeer-Drop; Piet Eikelenboom; W A van Gool; C.M. Duijn
The impact of apolipoprotein E on dementia in persons with Down's syndrome.
Neurobiology of aging 2008;29(6):828-35.
2008: Alejandro Arias-Vásquez; Yurii Aulchenko; Aaron Isaacs; Andy van Oosterhout; Kristel Sleegers; Albert Hofman; Christine Van Broeckhoven; Ben A Oostra; Monique Breteler; C.M. Duijn
Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study.
Journal of neurology 2008;255(5):655-62.
2008: Anne L Berends; Christianne J M De Groot; Eric J Sijbrands; Mark P S Sie; Sofie H Benneheij; Richard Pal; Roger Heydanus; Ben A Oostra; C.M. Duijn; Eric A P Steegers
Shared constitutional risks for maternal vascular-related pregnancy complications and future cardiovascular disease.
Hypertension 2008;51(4):1034-41.
2008: A H P Willemse-van Son; Gerard M Ribbers; W C J Hop; C.M. Duijn; Henk J Stam
Association between apolipoprotein-epsilon4 and long-term outcome after traumatic brain injury.
Journal of neurology, neurosurgery, and psychiatry 2008;79(4):426-30.
2008: Ilse A Hoppenbrouwers; Fan Liu; Yurii Aulchenko; George C Ebers; Ben A Oostra; C.M. Duijn; Rogier Q Hintzen
Maternal transmission of multiple sclerosis in a dutch population.
Archives of neurology 2008;65(3):345-8.
2008: A Cecile J W Janssens; Marta Gwinn; Linda A Bradley; Ben A Oostra; C.M. Duijn; Muin J Khoury
A critical appraisal of the scientific basis of commercial genomic profiles used to assess health risks and personalize health interventions.
American journal of human genetics 2008;82(3):593-9.
2008: Ernst J Franzek; Niels Sprangers; A Cecile J W Janssens; C.M. Duijn; Ben J van de Wetering
Prenatal exposure to the 1944-45 Dutch 'hunger winter' and addiction later in life.
Addiction (Abingdon, England) 2008;103(3):433-8.
2008: Stefania Boccia; Rayjean J Hung; Gualtiero Ricciardi; Francesco Gianfagna; Matthias P A Ebert; Jing-Yuan Fang; Chang-Ming Gao; Tobias Götze; Graziano Francesco; Marina Lacasaña Navarro; Dongxin Lin; Lizbeth López-Carrillo; You-Lin Qiao; Hongbing Shen; Rachael Stolzenberg-Solomon; Toshiro Takezaki; Yu-Rong Weng; Fang Fang Zhang; C.M. Duijn; Paolo Boffetta; Emanuela Taioli
Meta- and pooled analyses of the methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and gastric cancer risk: a huge-GSEC review.
American journal of epidemiology 2008;167(5):505-16.
2008: J J Miranda Geelhoed; Dennis O Mook-Kanamori; Jacqueline C M Witteman; Albert Hofman; C.M. Duijn; Henriëtte A Moll; Eric A P Steegers; Anita C S Hokken-Koelega; Vincent W V Jaddoe
Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study.
Clinical endocrinology 2008;68(3):382-9.
2008: Ronald van der Knaap; Claire Siemes; Jan-Willem W Coebergh; C.M. Duijn; Albert Hofman; Bruno H Ch Stricker
Renin-angiotensin system inhibitors, angiotensin I-converting enzyme gene insertion/deletion polymorphism, and cancer: the Rotterdam Study.
Cancer 2008;112(4):748-57.
2008: Manfred Kayser; Fan Liu; A Cecile J W Janssens; Fernando Rivadeneira; Oscar Lao; Kate van Duijn; Mark Vermeulen; Pascal P Arp; Mila M Jhamai; Wilfred F J van Ijcken; Johan T den Dunnen; Simon Heath; Diana Zelenika; Dominiek D G Despriet; Caroline C W Klaver; Johannes Vingerling; Paulus T V M de Jong; Albert Hofman; Yurii Aulchenko; André G Uitterlinden; Ben A Oostra; C.M. Duijn
Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.
American journal of human genetics 2008;82(2):411-23.
2008: Angela M González-Zuloeta Ladd; Alejandro Arias Vásquez; Fernando Rivadeneira; Claire Siemes; Albert Hofman; B H Ch Stricker; H A P Pols; André G Uitterlinden; C.M. Duijn
Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk.
Breast cancer research and treatment 2008;107(3):415-9.
2008: Vincent W V Jaddoe; C.M. Duijn; Albert J van der Heijden; Johan P Mackenbach; Henriëtte A Moll; Eric A P Steegers; Henning Tiemeier; André G Uitterlinden; Frank C Verhulst; Albert Hofman
The Generation R Study: design and cohort update until the age of 4 years.
European journal of epidemiology 2008;23(12):801-11.
2008: Mark P S Sie; Francesco U S Mattace-Raso; André G Uitterlinden; Pascal P Arp; Albert Hofman; Huibert A P Pols; Arnold P G Hoeks; Robert S Reneman; Roland Asmar; C.M. Duijn; Jacqueline C M Witteman
The interleukin-6-174 G/C promoter polymorphism and arterial stiffness; the Rotterdam Study.
Vascular health and risk management 2008;4(4):863-9.
2008: Abbas Dehghan; Mandy van Hoek; Eric J G Sijbrands; Ben A Oostra; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman
Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study.
BMC medicine 2008;6():30.
2008: M Carolina Pardo Silva; A Cecile J W Janssens; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn
Apolipoprotein E gene is related to mortality only in normal weight individuals: the Rotterdam Study.
European journal of epidemiology 2008;23(2):135-42.
2008: Stefania Boccia; Gabriella Cadoni; Fakhredin A Sayed-Tabatabaei; Mariangela Volante; Dario Arzani; Angelo De Lauretis; Caterina Cattel; Giovanni Almadori; C.M. Duijn; Gaetano Paludetti; Gualtiero Ricciardi
CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and neck cancer.
Journal of cancer research and clinical oncology 2008;134(1):93-100.
2007: Dennis O Mook-Kanamori; J J Miranda Geelhoed; Eric A P Steegers; Jacqueline C M Witteman; Albert Hofman; Henriëtte A Moll; C.M. Duijn; Anita C S Hokken-Koelega; Vincent W V Jaddoe
Insulin gene variable number of tandem repeats is not associated with weight from fetal life until infancy: the Generation R Study.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(6):741-8.
2007: Yurii Aulchenko; Jan Pullen; Wigard P Kloosterman; Mojgan Yazdanpanah; Albert Hofman; Norbert Vaessen; Pieter J L M Snijders; Dmitry Zubakov; Ian Mackay; Mark Olavesen; Balbinder Sidhu; Vicki E Smith; Alisoun Carey; Eugene Berezikov; André G Uitterlinden; Ronald H Plasterk; Ben A Oostra; C.M. Duijn
LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition.
Diabetes 2007;56(12):3020-6.
2007: Stefania Boccia; Francesco Gianfagna; Roberto Persiani; Antonio La Greca; Dario Arzani; Stefano Rausei; Domenico D'Ugo; Paolo Magistrelli; Paolo Villari; C.M. Duijn; Gualtiero Ricciardi
Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2007;12(6):635-44.
2007: Behrooz Alizadeh; Omer T Njajou; J M W Hazes; Albert Hofman; P Eline Slagboom; Huibert A P Pols; C.M. Duijn
The H63D variant in the HFE gene predisposes to arthralgia, chondrocalcinosis and osteoarthritis.
Annals of the rheumatic diseases 2007;66(11):1436-42.
2007: M J E van Rijn; Michiel J Bos; Aaron Isaacs; Mojgan Yazdanpanah; Alejandro Arias-Vásquez; Bruno H Ch Stricker; Olaf Klungel; Ben A Oostra; Peter J Koudstaal; Jacqueline C M Witteman; Albert Hofman; Monique Breteler; C.M. Duijn
Polymorphisms of the renin-angiotensin system are associated with blood pressure, atherosclerosis and cerebral white matter pathology.
Journal of neurology, neurosurgery, and psychiatry 2007;78(10):1083-7.
2007: Hedi Schelleman; Olaf Klungel; Jacqueline C M Witteman; Monique Breteler; Albert Hofman; C.M. Duijn; Anthonius de Boer; Bruno H Ch Stricker
Diuretic-gene interaction and the risk of myocardial infarction and stroke.
The pharmacogenomics journal 2007;7(5):346-52.
2007: C Reitz; Tom Den Heijer; C.M. Duijn; Albert Hofman; Monique Breteler
Relation between smoking and risk of dementia and Alzheimer disease: the Rotterdam Study.
Neurology 2007;69(10):998-1005.
2007: M Carolina Pardo Silva; A Cecile J W Janssens; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn
Cholesteryl ester transfer protein gene and coronary heart disease mortality: the Rotterdam study.
Journal of the American Geriatrics Society 2007;55(9):1483-4.
2007: A L Berends; Aida M Bertoli Avella; Christianne J M De Groot; C.M. Duijn; Ben A Oostra; Eric A P Steegers
STOX1 gene in pre-eclampsia and intrauterine growth restriction.
BJOG : an international journal of obstetrics and gynaecology 2007;114(9):1163-7.
2007: Francesco U S Mattace-Raso; Mark P S Sie; Tischa J M van der Cammen; M E Safar; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman
Insertion/deletion gene polymorphism of the angiotensin-converting enzyme and blood pressure changes in older adults. The Rotterdam study.
Journal of human hypertension 2007;21(9):736-40.
2007: Alejandro Arias-Vásquez; Lonneke de Lau; Luba M Pardo; Fan Liu; Bing-Jian Feng; Aida M Bertoli Avella; Aaron Isaacs; Yurii Aulchenko; Albert Hofman; Ben A Oostra; Monique Breteler; C.M. Duijn
Relationship of the Ubiquilin 1 gene with Alzheimer's and Parkinson's disease and cognitive function.
Neuroscience letters 2007;424(1):1-5.
2007: Pascual Sanchez-Juan; Simon N Cousens; Robert G Will; C.M. Duijn
Source of variant Creutzfeldt-Jakob disease outside United Kingdom.
Emerging infectious diseases 2007;13(8):1166-9.
2007: A Cecile J W Janssens; Ramal Moonesinghe; Quahne Yang; Ewout W Steyerberg; C.M. Duijn; Muin J Khoury
The impact of genotype frequencies on the clinical validity of genomic profiling for predicting common chronic diseases.
Genetics in medicine : official journal of the American College of Medical Genetics 2007;9(8):528-35.
2007: Leonieke M E van Koolwijk; Dominiek D G Despriet; C.M. Duijn; Luba M Pardo Cortes; Johannes Vingerling; Yurii Aulchenko; Ben A Oostra; Caroline C W Klaver; Hans G Lemij
Genetic contributions to glaucoma: heritability of intraocular pressure, retinal nerve fiber layer thickness, and optic disc morphology.
Investigative ophthalmology & visual science 2007;48(8):3669-76.
2007: Alejandro Arias-Vásquez; Aaron Isaacs; Yurii Aulchenko; Albert Hofman; Ben A Oostra; Monique Breteler; C.M. Duijn
The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease.
Neurogenetics 2007;8(3):189-93.
2007: Fan Liu; Alejandro Arias-Vásquez; Kristel Sleegers; Yurii Aulchenko; Manfred Kayser; Pascual Sanchez-Juan; Bing-Jian Feng; Aida M Bertoli Avella; John C van Swieten; Tatiana I Axenovich; Peter Heutink; Christine Van Broeckhoven; Ben A Oostra; C.M. Duijn
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population.
American journal of human genetics 2007;81(1):17-31.
2007: Angela M González-Zuloeta Ladd; Fan Liu; M P W A Houben; Alejandro Arias-Vásquez; Claire Siemes; A Cecile J W Janssens; J W W Coebergh; Albert Hofman; Joop A M J L Janssen; Bruno H Ch Stricker; C.M. Duijn
IGF-1 CA repeat variant and breast cancer risk in postmenopausal women.
European journal of cancer (Oxford, England : 1990) 2007;43(11):1718-22.
2007: Loes E Visser; Ron van Schaik; Alexander H Jan Danser; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn; André G Uitterlinden; Huibert A P Pols; Bruno H Ch Stricker
The risk of myocardial infarction in patients with reduced activity of cytochrome P450 2C9.
Pharmacogenetics and genomics 2007;17(7):473-9.
2007: Nahid Yazdanpanah; Fernando Rivadeneira; Joyce B J van Meurs; M Carola Zillikens; Pascal P Arp; Albert Hofman; C.M. Duijn; Huibert A P Pols; André G Uitterlinden
The -1997 G/T and Sp1 polymorphisms in the collagen type I alpha1 (COLIA1) gene in relation to changes in femoral neck bone mineral density and the risk of fracture in the elderly: the Rotterdam study.
Calcified tissue international 2007;81(1):18-25.
2007: Paswal Sánchez-Juan; M P W A Houben; Jorrit I Hoff; Casper Jansen; Mark P S Sie; M J E van Rijn; James W Ironside; Robert G Will; C.M. Duijn; Annemieke Rozemuller
The first case of variant Creutzfeldt-Jakob disease in The Netherlands.
Journal of neurology 2007;254(7):958-60.
2007: Mojgan Yazdanpanah; Yurii Aulchenko; Albert Hofman; Joop A M J L Janssen; Fakhredin A Sayed-Tabatabaei; Ron van Schaik; Olaf Klungel; Bruno H Ch Stricker; Huibert A P Pols; Jacqueline C M Witteman; Steven W J Lamberts; Ben A Oostra; C.M. Duijn
Effects of the renin-angiotensin system genes and salt sensitivity genes on blood pressure and atherosclerosis in the total population and patients with type 2 diabetes.
Diabetes 2007;56(7):1905-12.
2007: Aaron Isaacs; Yurii Aulchenko; Albert Hofman; Eric J G Sijbrands; Fakhredin A Sayed-Tabatabaei; Olaf Klungel; Anke Hilse Maitland-van der Zee; Bruno H Ch Stricker; Ben A Oostra; Jacqueline C M Witteman; C.M. Duijn
Epistatic effect of cholesteryl ester transfer protein and hepatic lipase on serum high-density lipoprotein cholesterol levels.
The Journal of clinical endocrinology and metabolism 2007;92(7):2680-7.
2007: Josine L Min; Ingrid Meulenbelt; Margreet Kloppenburg; C.M. Duijn; P Eline Slagboom
Mutation analysis of candidate genes within the 2q33.3 linkage area for familial early-onset generalised osteoarthritis.
European journal of human genetics : EJHG 2007;15(7):791-9.
2007: Pascual Sanchez-Juan; Raquel Sánchez-Valle; Alison Green; Anna Ladogana; Natividad Cuadrado-Corrales; Eva Mitrová; Katharina Stoeck; Theodoros Sklaviadis; Jerzy Kulczycki; Klaus Hess; Anna Krasnianski; Michele Equestre; Danka Slivarichová; Albert Saiz; Miguel Calero; Maurizio Pocchiari; Richard Knight; C.M. Duijn; Inga Zerr
Influence of timing on CSF tests value for Creutzfeldt-Jakob disease diagnosis.
Journal of neurology 2007;254(7):901-6.
2007: Hedi Schelleman; Olaf Klungel; Jacqueline C M Witteman; Albert Hofman; C.M. Duijn; Anthonius de Boer; Bruno H Ch Stricker
Pharmacogenetic interactions of three candidate gene polymorphisms with ACE-inhibitors or beta-blockers and the risk of atherosclerosis.
British journal of clinical pharmacology 2007;64(1):57-66.
2007: Aaron Isaacs; Fakhredin A Sayed-Tabatabaei; Albert Hofman; Ben A Oostra; Olaf Klungel; Anke-Hilse Maitland-Vander Zee; Bruno H Ch Stricker; Jacqueline C M Witteman; C.M. Duijn
The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2007;14(3):419-21.
2007: Mark P S Sie; Francesco U S Mattace-Raso; André G Uitterlinden; Pascal P Arp; Albert Hofman; Arnold P G Hoeks; Robert S Reneman; Roland Asmar; C.M. Duijn; Jacqueline C M Witteman
TGF-beta1 polymorphisms and arterial stiffness; the Rotterdam Study.
Journal of human hypertension 2007;21(6):431-7.
2007: Yurii Aulchenko; Stephan Ripke; Aaron Isaacs; C.M. Duijn
GenABEL: an R library for genome-wide association analysis.
Bioinformatics (Oxford, England) 2007;23(10):1294-6.
2007: Ewoud J van Dijk; Niels D Prins; Albert Hofman; C.M. Duijn; Peter J Koudstaal; Monique Breteler
Plasma beta amyloid and impaired CO2-induced cerebral vasomotor reactivity.
Neurobiology of aging 2007;28(5):707-12.
2007: Kristel Sleegers; Inge de Koning; Yurii Aulchenko; M J E van Rijn; M P W A Houben; Esther A Croes; John C van Swieten; Ben A Oostra; C.M. Duijn
Cerebrovascular risk factors do not contribute to genetic variance of cognitive function: the ERF study.
Neurobiology of aging 2007;28(5):735-41.
2007: Hedi Schelleman; Olaf Klungel; Jacqueline C M Witteman; Monique Breteler; Mojgan Yazdanpanah; Alexander Hessel Jan Danser; Albert Hofman; C.M. Duijn; Anthonius de Boer; Bruno H Ch Stricker
Angiotensinogen M235T polymorphism and the risk of myocardial infarction and stroke among hypertensive patients on ACE-inhibitors or beta-blockers.
European journal of human genetics : EJHG 2007;15(4):478-84.
2007: Sharmila S Boekhoorn; Johannes Vingerling; André G Uitterlinden; Joyce B J van Meurs; C.M. Duijn; Huibert A P Pols; Albert Hofman; Paulus T V M de Jong
Estrogen receptor alpha gene polymorphisms associated with incident aging macula disorder.
Investigative ophthalmology & visual science 2007;48(3):1012-7.
2007: M J E van Rijn; A F C Schut; Yurii Aulchenko; jaap deinum; Fakhredin A Sayed-Tabatabaei; Mojgan Yazdanpanah; Aaron Isaacs; Tatiana I Axenovich; Irina V Zorkoltseva; M Carola Zillikens; Huibert A P Pols; Jacqueline C M Witteman; Ben A Oostra; C.M. Duijn
Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes.
Journal of hypertension 2007;25(3):565-70.
2007: Angela M González-Zuloeta Ladd; Alejandro Arias-Vásquez; Claire Siemes; Mojgan Yazdanpanah; J W W Coebergh; Albert Hofman; Bruno H Ch Stricker; C.M. Duijn
Differential roles of Angiotensinogen and Angiotensin Receptor type 1 polymorphisms in breast cancer risk.
Breast cancer research and treatment 2007;101(3):299-304.
2007: Alison Green; Pascual Sanchez-Juan; Anna Ladogana; Natividad Cuadrado-Corrales; Raquel Sánchez-Valle; Eva Mitrová; Katharina Stoeck; Theodoros Sklaviadis; Jerzy Kulczycki; Uta Heinemann; Klaus Hess; Danka Slivarichová; Albert Saiz; Miguel Calero; Vittorio Mellina; Richard Knight; C.M. Duijn; Inga Zerr
CSF analysis in patients with sporadic CJD and other transmissible spongiform encephalopathies.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2007;14(2):121-4.
2007: Pascual Sánchez-Juan; Matthew Bishop; Alison Green; Claudia Giannattasio; Alejandro Arias-Vasquez; Anna Poleggi; Richard S G Knight; C.M. Duijn
No evidence for association between tau gene haplotypic variants and susceptibility to Creutzfeldt-Jakob disease.
BMC medical genetics 2007;8():77.
2007: Najaf Amin; C.M. Duijn; Yurii Aulchenko
A genomic background based method for association analysis in related individuals.
PloS one 2007;2(12):e1274.
2007: Stefania Boccia; Fakhredin A Sayed-Tabatabaei; Roberto Persiani; Francesco Gianfagna; Stefano Rausei; Dario Arzani; Antonio La Greca; Domenico D'Ugo; Giuseppe La Torre; C.M. Duijn; Gualtiero Ricciardi
Polymorphisms in metabolic genes, their combination and interaction with tobacco smoke and alcohol consumption and risk of gastric cancer: a case-control study in an Italian population.
BMC cancer 2007;7():206.
2007: Albert Hofman; Monique Breteler; C.M. Duijn; Gabriel P Krestin; Huibert A P Pols; Bruno H Ch Stricker; Henning Tiemeier; André G Uitterlinden; Johannes Vingerling; Jacqueline C M Witteman
The Rotterdam Study: objectives and design update.
European journal of epidemiology 2007;22(11):819-29.
2007: A W Coppus; Durk Fekkes; W M A Verhoeven; Siegfried Tuinier; J I M Egger; C.M. Duijn
Plasma amino acids and neopterin in healthy persons with Down's syndrome.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(8):1041-5.
2007: Stefania Boccia; Giuseppe La Torre; Roberto Persiani; Domenico D'Ugo; C.M. Duijn; Gualtiero Ricciardi
A critical appraisal of epidemiological studies comes from basic knowledge: a reader's guide to assess potential for biases.
World journal of emergency surgery : WJES 2007;2():7.
2007: Aaron Isaacs; Fakhredin A Sayed-Tabatabaei; Yurii Aulchenko; M Carola Zillikens; Eric J G Sijbrands; A F C Schut; Wim P F Rutten; Huibert A P Pols; Jacqueline C M Witteman; Ben A Oostra; C.M. Duijn
Heritabilities, apolipoprotein E, and effects of inbreeding on plasma lipids in a genetically isolated population: the Erasmus Rucphen Family Study.
European journal of epidemiology 2007;22(2):99-105.
2007: I A Hoppenbrouwers; L M Pardo Cortes; Yurii Aulchenko; Kees Sintnicolaas; Omer T Njajou; Pieter J L M Snijders; Ben A Oostra; C.M. Duijn; Rogier Q Hintzen
Familial clustering of multiple sclerosis in a Dutch genetic isolate.
Multiple sclerosis (Houndmills, Basingstoke, England) 2007;13(1):17-24.
2007: Nadia A Sutedja; Richard J Sinke; Paul van Vught; Michiel W Van der Linden; J H J Wokke; C.M. Duijn; Omer T Njajou; Yvonne van der Schouw; Jan Veldink; Leonard H Van den Berg
The association between H63D mutations in HFE and amyotrophic lateral sclerosis in a Dutch population.
Archives of neurology 2007;64(1):63-7.
2007: Gerly M van der Vleuten; Aaron Isaacs; Wu-Wei Zeng; Ewoud ter Avest; Philippa J Talmud; Geesje M Dallinga-Thie; C.M. Duijn; Anton F H Stalenhoef; Jacqueline de Graaf
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia.
Biochimica et biophysica acta 2007;1772(1):81-8.
2007: Gerly M van der Vleuten; Aaron Isaacs; Anneke Hijmans; C.M. Duijn; Anton F H Stalenhoef; Jacqueline de Graaf
The involvement of upstream stimulatory factor 1 in Dutch patients with familial combined hyperlipidemia.
Journal of lipid research 2007;48(1):193-200.
2007: Angela M González-Zuloeta Ladd; Alejandro Arias-Vásquez; Claire Siemes; J W W Coebergh; Albert Hofman; Jacqueline C M Witteman; André G Uitterlinden; Bruno H Ch Stricker; C.M. Duijn
Transforming-growth factor beta1 Leu10Pro polymorphism and breast cancer morbidity.
European journal of cancer (Oxford, England : 1990) 2007;43(2):371-4.
2007: Stefania Boccia; Angelo De Lauretis; Francesco Gianfagna; C.M. Duijn; Gualtiero Ricciardi
CYP2E1PstI/RsaI polymorphism and interaction with tobacco, alcohol and GSTs in gastric cancer susceptibility: A meta-analysis of the literature.
Carcinogenesis 2007;28(1):101-6.
2006: Sandra López León; A Cecile J W Janssens; Albert Hofman; Stephan Claes; Monique Breteler; Henning Tiemeier; C.M. Duijn
No association between the angiotensin-converting enzyme gene and major depression: a case-control study and meta-analysis.
Psychiatric genetics 2006;16(6):225-6.
2006: M J E van Rijn; Michiel J Bos; Mojgan Yazdanpanah; Aaron Isaacs; Alejandro Arias-Vásquez; Peter J Koudstaal; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn; Monique Breteler
Alpha-adducin polymorphism, atherosclerosis, and cardiovascular and cerebrovascular risk.
Stroke; a journal of cerebral circulation 2006;37(12):2930-4.
2006: A Cecile J W Janssens; Ewout W Steyerberg; Yebin Jiang; J Dik F Habbema; C.M. Duijn; Lindsey A Criswell
Value of the HLA-DRB1 shared epitope for predicting radiographic damage in rheumatoid arthritis depends on the individual patient risk profile.
The Journal of rheumatology 2006;33(12):2383-9.
2006: Ingrid Meulenbelt; Josine L Min; C.M. Duijn; Margreet Kloppenburg; Ferdinand C Breedveld; P Eline Slagboom
Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes.
European journal of human genetics : EJHG 2006;14(12):1280-7.
2006: Mojgan Yazdanpanah; Fakhredin A Sayed-Tabatabaei; Joop A M J L Janssen; Ingrid Rietveld; Albert Hofman; Theo Stijnen; Huibert A P Pols; Steven W J Lamberts; Jacqueline C M Witteman; C.M. Duijn
IGF-I gene promoter polymorphism is a predictor of survival after myocardial infarction in patients with type 2 diabetes.
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(5):751-6.
2006: Fan Liu; S Elefante; C.M. Duijn; Yurii Aulchenko
Ignoring distant genealogic loops leads to false-positives in homozygosity mapping.
Annals of human genetics 2006;70(Pt 6):965-70.
2006: Mark P S Sie; André G Uitterlinden; Michiel J Bos; Pascal P Arp; Monique Breteler; Peter J Koudstaal; Huibert A P Pols; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman
TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke: the Rotterdam Study.
Stroke; a journal of cerebral circulation 2006;37(11):2667-71.
2006: Kristel Sleegers; Nathalie Brouwers; Ilse Gijselinck; Jessie Theuns; Dirk Goossens; Jan Wauters; Jurgen Del-Favero; Marc Cruts; C.M. Duijn; Christine Van Broeckhoven
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy.
Brain : a journal of neurology 2006;129(Pt 11):2977-83.
2006: Mojgan Yazdanpanah; Fakhredin A Sayed-Tabatabaei; Albert Hofman; Yurii Aulchenko; Ben A Oostra; Bruno H Ch Stricker; Huibert A P Pols; Steven W J Lamberts; Jacqueline C M Witteman; Joop A M J L Janssen; C.M. Duijn
The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes.
Diabetes 2006;55(10):2922-7.
2006: Fernando Rivadeneira; Joyce B J van Meurs; Jojanneke Kant; M Carola Zillikens; Lisette Stolk; Thomas J Beck; Pascal P Arp; Stephanie C E Schuit; Albert Hofman; Jeanine J Houwing-Duistermaat; C.M. Duijn; Johannes P T M van Leeuwen; Huibert A P Pols; André G Uitterlinden
Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2006;21(9):1443-56.
2006: Steven J Collins; Pascual Sanchez-Juan; Colin L Masters; Genevieve M Klug; C.M. Duijn; Anna Poleggi; Maurizio Pocchiari; Susanna Almonti; Natividad Cuadrado-Corrales; Jesús de Pedro-Cuesta; Herbert Budka; Ellen Gelpi; Markus Glatzel; M Tolnay; E Hewer; Inga Zerr; Uta Heinemann; H A Kretszchmar; Gerard H Jansen; E Olsen; Eva Mitrova; Annick Alpérovitch; Jean-Philippe Brandel; J Mackenzie; K Murray; Robert G Will
Determinants of diagnostic investigation sensitivities across the clinical spectrum of sporadic Creutzfeldt-Jakob disease.
Brain : a journal of neurology 2006;129(Pt 9):2278-87.
2006: Marc Cruts; Ilse Gijselinck; Julie van der Zee; Sebastiaan Engelborghs; Hans Wils; Daniel Pirici; Rosa Rademakers; Rik Vandenberghe; Bart Dermaut; Jean-Jacques Martin; C.M. Duijn; Karin Peeters; Raf Sciot; Patrick Santens; Tim De Pooter; Maria Mattheijssens; Marleen Van den Broeck; Ivy Cuijt; Krist'l Vennekens; Peter Paul De Deyn; Samir Kumar-Singh; Christine Van Broeckhoven
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.
Nature 2006;442(7105):920-4.
2006: Pascual Sanchez-Juan; Alison Green; Anna Ladogana; Natividad Cuadrado-Corrales; R Sáanchez-Valle; E Mitrováa; Katharina Stoeck; Theodoros Sklaviadis; Jerzy Kulczycki; Klaus Hess; Monika Bodemer; Danka Slivarichová; Albert Saiz; Miguel Calero; L Ingrosso; Richard Knight; A Cecile J W Janssens; C.M. Duijn; Inga Zerr
CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease.
Neurology 2006;67(4):637-43.
2006: Ingrid Rietveld; M Kamran Ikram; Johannes Vingerling; Albert Hofman; Huibert A P Pols; Steven W J Lamberts; Paulus T V M de Jong; C.M. Duijn; Joop A M J L Janssen
An igf-I gene polymorphism modifies the risk of diabetic retinopathy.
Diabetes 2006;55(8):2387-91.
2006: Josine L Min; Ingrid Meulenbelt; Naghmeh Riyazi; Margreet Kloppenburg; Jeanine J Houwing-Duistermaat; Albert B Seymour; C.M. Duijn; P Eline Slagboom
Association of matrilin-3 polymorphisms with spinal disc degeneration and osteoarthritis of the first carpometacarpal joint of the hand.
Annals of the rheumatic diseases 2006;65(8):1060-6.
2006: Dominiek D G Despriet; Caroline C W Klaver; Jacqueline C M Witteman; Arthur A B Bergen; Isabella Kardys; Moniek P M de Maat; Sharmila S Boekhoorn; Johannes Vingerling; Albert Hofman; Ben A Oostra; André G Uitterlinden; Theo Stijnen; C.M. Duijn; Paulus T V M de Jong
Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration.
JAMA : the journal of the American Medical Association 2006;296(3):301-9.
2006: A Cecile J W Janssens; Yurii Aulchenko; Stefano Elefante; Gerard J J M Borsboom; Ewout W Steyerberg; C.M. Duijn
Predictive testing for complex diseases using multiple genes: fact or fiction?
Genetics in medicine : official journal of the American College of Medical Genetics 2006;8(7):395-400.
2006: Hedi Schelleman; Olaf Klungel; Jacqueline C M Witteman; Albert Hofman; C.M. Duijn; Anthonius de Boer; Bruno H Ch Stricker
The influence of the alpha-adducin G460W polymorphism and angiotensinogen M235T polymorphism on antihypertensive medication and blood pressure.
European journal of human genetics : EJHG 2006;14(7):860-6.
2006: Albert Hofman; Paulus T V M de Jong; C.M. Duijn; Monique Breteler
Epidemiology of neurological diseases in elderly people: what did we learn from the Rotterdam Study?
Lancet neurology 2006;5(6):545-50.
2006: Jessie Theuns; Nathalie Brouwers; Sebastiaan Engelborghs; Kristel Sleegers; Veerle Bogaerts; Ellen Corsmit; Tim De Pooter; C.M. Duijn; Peter Paul De Deyn; Christine Van Broeckhoven
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.
American journal of human genetics 2006;78(6):936-46.
2006: Fakhredin A Sayed-Tabatabaei; Ben A Oostra; Aaron Isaacs; C.M. Duijn; Jacqueline C M Witteman
ACE polymorphisms.
Circulation research 2006;98(9):1123-33.
2006: Ingrid Rietveld; Albert Hofman; Huibert A P Pols; C.M. Duijn; Steven W J Lamberts; Joop A M J L Janssen
An insulin-like growth factor-I gene polymorphism modifies the risk of microalbuminuria in subjects with an abnormal glucose tolerance.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(5):715-21.
2006: Mojgan Yazdanpanah; Ingrid Rietveld; Joop A M J L Janssen; Omer T Njajou; Albert Hofman; Theo Stijnen; Huibert A P Pols; Steven W J Lamberts; Jacqueline C M Witteman; C.M. Duijn
An insulin-like growth factor-I promoter polymorphism is associated with increased mortality in subjects with myocardial infarction in an elderly Caucasian population.
The American journal of cardiology 2006;97(9):1274-6.
2006: Susan K Service; Joseph DeYoung; Maria Karayiorgou; J Louw Roos; Herman Pretorious; Gabriel Bedoya; Jorge Ospina; Andres Ruiz-Linares; antonio macedo; Joana Almeida Palha; Peter Heutink; Yurii Aulchenko; Ben Oostra; C.M. Duijn; Marjo-Riitta Jarvelin; Teppo Varilo; Lynette Peddle; Proton Rahman; Giovanna Piras; Maria Monne; Sarah Murray; Luana Galver; Leena Peltonen; Chiara Sabatti; ANDREW COLLINS; Nelson B Freimer
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.
Nature genetics 2006;38(5):556-60.
2006: Isabella Kardys; Caroline C W Klaver; Dominiek D G Despriet; Arthur A B Bergen; André G Uitterlinden; Albert Hofman; Ben A Oostra; C.M. Duijn; Paulus T V M de Jong; Jacqueline C M Witteman
A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study.
Journal of the American College of Cardiology 2006;47(8):1568-75.
2006: Regie Lyn P Santos; M Carola Zillikens; Fernando Rivadeneira; Huibert A P Pols; Ben A Oostra; C.M. Duijn; Yurii Aulchenko
Heritability of fasting glucose levels in a young genetically isolated population.
Diabetologia 2006;49(4):667-72.
2006: M P W A Houben; Dorry Boll; Ron Herings; Mariel Casparie; Cees C Tijssen; C.M. Duijn; Bruno H Ch Stricker
The association between antihypertensive drugs and glioma.
British journal of cancer 2006;94(5):752-6.
2006: Aida M Bertoli Avella; Marieke C J Dekker; Yurii Aulchenko; Jeanine J Houwing-Duistermaat; Erik J Simons; Leon Testers; Luba M Pardo; Tessa Rademaker-Havinga; Pieter J L M Snijders; John C van Swieten; Vincenzo Bonifati; Peter Heutink; C.M. Duijn; Ben A Oostra
Evidence for novel loci for late-onset Parkinson's disease in a genetic isolate from the Netherlands.
Human genetics 2006;119(1-2):51-60.
2006: Dirk van West; Filip Van Den Eede; Jurgen Del-Favero; Daniel Souery; Karl-Fredrik Norrback; C.M. Duijn; Sam Sluijs; Rolf Adolfsson; Julien Mendlewicz; Dirk Deboutte; Christine Van Broeckhoven; Stephan J Claes
Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):620-7.
2006: Hedi Schelleman; Olaf Klungel; C.M. Duijn; Jacqueline C M Witteman; Albert Hofman; Anthonius de Boer; Bruno H Ch Stricker
Drug-gene interaction between the insertion/deletion polymorphism of the angiotensin-converting enzyme gene and antihypertensive therapy.
The Annals of pharmacotherapy 2006;40(2):212-8.
2006: M Kamran Ikram; Joop A M J L Janssen; Anna M E Roos; Ingrid Rietveld; Jacqueline C M Witteman; Monique Breteler; Albert Hofman; C.M. Duijn; Paulus T V M de Jong
Retinal vessel diameters and risk of impaired fasting glucose or diabetes: the Rotterdam study.
Diabetes 2006;55(2):506-10.
2006: Nathalie Brouwers; Kristel Sleegers; Sebastiaan Engelborghs; Veerle Bogaerts; C.M. Duijn; Peter Paul De Deyn; Christine Van Broeckhoven; Bart Dermaut
The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.
Neuroscience letters 2006;392(1-2):72-4.
2006: A Cecile J W Janssens; C.M. Duijn
Towards predictive genetic testing of complex diseases.
European journal of epidemiology 2006;21(12):869-70.
2006: Jesús de Pedro-Cuesta; Markus Glatzel; Javier Almazán; Katharina Stoeck; Vittorio Mellina; Maria Puopolo; Maurizio Pocchiari; Inga Zerr; Hans A Kretszchmar; Jean-Philippe Brandel; Nicole Delasnerie-Lauprêtre; Annick Alpérovitch; C.M. Duijn; Pascual Sanchez-Juan; Steven Collins; Victoria Lewis; Gerard H Jansen; Michael B Coulthart; Ellen Gelpi; Herbert Budka; Eva Mitrova
Human transmissible spongiform encephalopathies in eleven countries: diagnostic pattern across time, 1993-2002.
BMC public health 2006;6():278.
2006: Omer T Njajou; Behrooz Alizadeh; Yurii Aulchenko; M Carola Zillikens; Huibert A P Pols; Ben A Oostra; D W Swinkels; C.M. Duijn
Heritability of serum iron, ferritin and transferrin saturation in a genetically isolated population, the Erasmus Rucphen Family (ERF) Study.
Human heredity 2006;61(4):222-8.
2006: C.M. Duijn; Helma Ruijs; Aura Timen
Second probable case of vCJD in the Netherlands.
Euro surveillance : bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2006;11(6):E060629.4.
2006: Angela M González-Zuloeta Ladd; Alejandro Arias-Vásquez; Jacqueline C M Witteman; André G Uitterlinden; J W W Coebergh; Albert Hofman; Bruno H Ch Stricker; C.M. Duijn
Interleukin 6 G-174 C polymorphism and breast cancer risk.
European journal of epidemiology 2006;21(5):373-6.
2006: M P W A Houben; K K H Aben; J L J M Teepen; Antoinette Y N Schouten-Van Meeteren; Cees C Tijssen; C.M. Duijn; Dorry Boll
Stable incidence of childhood and adult glioma in The Netherlands, 1989-2003.
Acta oncologica (Stockholm, Sweden) 2006;45(3):272-9.
2006: M P W A Houben; Dorry Boll; J M Birch; Cees C Tijssen; C.M. Duijn; Richard J Q McNally
Space-time clustering of glioma cannot be attributed to specific histological subgroups.
European journal of epidemiology 2006;21(3):197-201.
2006: M J E van Rijn; A J C Slooter; Michiel J Bos; Claudia Bacanhim Catarino; Peter J Koudstaal; Albert Hofman; Monique Breteler; C.M. Duijn
Insulin-like growth factor I promoter polymorphism, risk of stroke, and survival after stroke: the Rotterdam study.
Journal of neurology, neurosurgery, and psychiatry 2006;77(1):24-7.
2006: Mark P S Sie; Fakhredin A Sayed-Tabatabaei; Hok-Hay S Oei; André G Uitterlinden; Hubert A P Pols; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman
Interleukin 6 -174 g/c promoter polymorphism and risk of coronary heart disease: results from the rotterdam study and a meta-analysis.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):212-7.
2005: C Jansen; M P W A Houben; Jorrit I Hoff; P Sanchez-Juan; A J M Rozemuller; C.M. Duijn
[The first patient with the new variant of Creutzfeldt-Jakob's disease in The Netherlands].
Nederlands tijdschrift voor geneeskunde 2005;149(53):2949-54.
2005: Luba M Pardo; C.M. Duijn
In search of genes involved in neurodegenerative disorders.
Mutation research 2005;592(1-2):89-101.
2005: M P W A Houben; Dorry Boll; J M Birch; Cees C Tijssen; C.M. Duijn; Richard J Q McNally
Space-time clustering patterns of gliomas in The Netherlands suggest an infectious aetiology.
European journal of cancer (Oxford, England : 1990) 2005;41(18):2917-23.
2005: Fakhredin A Sayed-Tabatabaei; M J E van Rijn; A F C Schut; Yurii Aulchenko; Esther A Croes; M Carola Zillikens; Huibert A P Pols; Jacqueline C M Witteman; Ben A Oostra; C.M. Duijn
Heritability of the function and structure of the arterial wall: findings of the Erasmus Rucphen Family (ERF) study.
Stroke; a journal of cerebral circulation 2005;36(11):2351-6.
2005: Gabor Geza Kovacs; Maria Puopolo; Anna Ladogana; Maurizio Pocchiari; Herbert Budka; C.M. Duijn; Steven J Collins; Alison Boyd; Antonio Giulivi; Michael B Coulthart; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Inga Zerr; Hans A Kretzschmar; Jesús de Pedro-Cuesta; Miguel Calero-Lara; Markus Glatzel; Adriano Aguzzi; Matthew Bishop; Richard Knight; Girma Belay; Robert Will; Eva Mitrova
Genetic prion disease: the EUROCJD experience.
Human genetics 2005;118(2):166-74.
2005: M J E van Rijn; A J C Slooter; A F C Schut; Aaron Isaacs; Yurii Aulchenko; Pieter J L M Snijders; L Jaap Kappelle; John C van Swieten; Ben A Oostra; C.M. Duijn
Familial aggregation, the PDE4D gene, and ischemic stroke in a genetically isolated population.
Neurology 2005;65(8):1203-9.
2005: M P W A Houben; C.M. Duijn; J W W Coebergh; Cees C Tijssen
[Gliomas: the role of environmental risk factors and genetic predisposition].
Nederlands tijdschrift voor geneeskunde 2005;149(41):2268-72.
2005: Rosa Rademakers; Marc Cruts; Kristel Sleegers; Bart Dermaut; Jessie Theuns; Yurii Aulchenko; Stefan Weckx; Tim De Pooter; Marleen Van den Broeck; Ellen Corsmit; Peter De Rijk; Jurgen Del-Favero; John C van Swieten; C.M. Duijn; Christine Van Broeckhoven
Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample.
American journal of human genetics 2005;77(4):643-52.
2005: Angela M González-Zuloeta Ladd; Alejandro Arias Vásquez; Fakhredin A Sayed-Tabatabaei; Dorry Boll; Albert Hofman; Omer T Njajou; Bruno H Ch Stricker; C.M. Duijn
Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(9):2143-6.
2005: Hok-Hay S Oei; Fakhredin A Sayed-Tabatabaei; Albert Hofman; Matthijs Oudkerk; C.M. Duijn; Jacqueline C M Witteman
The association between angiotensin-converting enzyme gene polymorphism and coronary calcification. The Rotterdam Coronary Calcification Study.
Atherosclerosis 2005;182(1):169-73.
2005: Donald J Lehmann; Mario Cortina Borja; Donald R Warden; A David Smith; Kristel Sleegers; Jonathan A Prince; C.M. Duijn; Pat Kehoe
Large meta-analysis establishes the ACE insertion-deletion polymorphism as a marker of Alzheimer's disease.
American journal of epidemiology 2005;162(4):305-17.
2005: Kristel Sleegers; Tom Den Heijer; Ewoud J van Dijk; Albert Hofman; Aida M Bertoli Avella; Peter J Koudstaal; Monique Breteler; C.M. Duijn
ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala.
Neurobiology of aging 2005;26(8):1153-9.
2005: Rosa Rademakers; Kristel Sleegers; Jessie Theuns; Marleen Van den Broeck; Samira Bel Kacem; Lars-Göran Nilsson; Rolf Adolfsson; C.M. Duijn; Christine Van Broeckhoven; Marc Cruts
Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease.
Neurobiology of aging 2005;26(8):1145-51.
2005: Alejandro Arias-Vásquez; Fakhredin A Sayed-Tabatabaei; A F C Schut; Albert Hofman; A M Bertolli-Avella; Jeannette M Vergeer; Yurii Aulchenko; Jacqueline C M Witteman; C.M. Duijn
Angiotensin converting enzyme gene, smoking and mortality in a population-based study.
European journal of clinical investigation 2005;35(7):444-9.
2005: Rachid El Galta; C.M. Duijn; J C van Houwelingen; Jeanine J Houwing-Duistermaat
Score statistic to test for genetic correlation for proband-family design.
Annals of human genetics 2005;69(Pt 4):373-81.
2005: Loes E Visser; Ron van Schaik; Martin van Vliet; Paul H Trienekens; Peter A G M de Smet; Arnold G Vulto; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker
Allelic variants of cytochrome P450 2C9 modify the interaction between nonsteroidal anti-inflammatory drugs and coumarin anticoagulants.
Clinical pharmacology and therapeutics 2005;77(6):479-85.
2005: Leen M 't Hart; Torben Hansen; Ingrid Rietveld; Jacqueline M Dekker; Giel Nijpels; George M C Janssen; Pascal A Arp; André G Uitterlinden; Torben Jørgensen; Knut Borch-Johnsen; Huibert A P Pols; Oluf Pedersen; C.M. Duijn; Robert J Heine; J Antonie Maassen
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
Diabetes 2005;54(6):1892-5.
2005: Anna Ladogana; Maria Puopolo; Esther Croes; Herbert Budka; Christa Jarius; Steven Collins; Genevieve M Klug; T Sutcliffe; Antonio Giulivi; A Alperovitch; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Sigrid Poser; Hans A Kretzschmar; I Rietveld; Eva Mitrova; J de Pedro Cuesta; P Martinez-Martin; Markus Glatzel; Adriano Aguzzi; Richard Knight; H Ward; Maurizio Pocchiari; C.M. Duijn; Robert G Will; Inga Zerr
Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada.
Neurology 2005;64(9):1586-91.
2005: Behrooz Alizadeh; Omer T Njajou; C Bijkerk; Ingrid Meulenbelt; S C De Wildt; Albert Hofman; Huibert A P Pols; P Eline Slagboom; C.M. Duijn
Evidence for a role of the genomic region of the gene encoding for the alpha1 chain of type IX collagen (COL9A1) in hip osteoarthritis: A population-based study.
Arthritis and rheumatism 2005;52(5):1437-42.
2005: Sandra López León; Esther A Croes; Fakhredin A Sayed-Tabatabaei; Stephan Claes; Christine Van Broeckhoven; C.M. Duijn
The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis.
Biological psychiatry 2005;57(9):999-1003.
2005: L M Pardo; Ian Mackay; Ben A Oostra; C.M. Duijn; Yurii Aulchenko
The effect of genetic drift in a young genetically isolated population.
Annals of human genetics 2005;69(Pt 3):288-95.
2005: Catey Bunce; Roger A Hitchings; C.M. Duijn; Paulus T V M de Jong; Johannes Vingerling
Associations between the deletion polymorphism of the angiotensin 1-converting enzyme gene and ocular signs of primary open-angle glaucoma.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2005;243(4):294-9.
2005: Josine L Min; Ingrid Meulenbelt; Naghmeh Riyazi; Margreet Kloppenburg; Jeanine J Houwing-Duistermaat; Albert B Seymour; Huibert A P Pols; C.M. Duijn; P Eline Slagboom
Association of the Frizzled-related protein gene with symptomatic osteoarthritis at multiple sites.
Arthritis and rheumatism 2005;52(4):1077-80.
2005: Hedi Schelleman; Olaf Klungel; C.M. Duijn; Jacqueline C M Witteman; Albert Hofman; Anthonius de Boer; Bruno H Ch Stricker
Insertion/deletion polymorphism of the ACE gene and adherence to ACE inhibitors.
British journal of clinical pharmacology 2005;59(4):483-5.
2005: Aida M Bertoli-Avella; José L Giroud-Benitez; Ali Akyol; Egberto Barbosa; Onno Schaap; Herma C van der Linde; Emilia Martignoni; Leonardo Lopiano; Paolo Lamberti; Emiliana Fincati; Angelo Antonini; Fabrizio Stocchi; Pasquale Montagna; Ferdinando Squitieri; Paolo Marini; Giovanni Abbruzzese; Giovanni Fabbrini; Roberto Marconi; Alessio Dalla Libera; Giorgio Trianni; Marco Guidi; Antonio De Gaetano; Gustavo Boff Maegawa; Antonino De Leo; Virgilio Gallai; Giulia de Rosa; Nicola Vanacore; Giuseppe Meco; C.M. Duijn; Ben A Oostra; Peter Heutink; Vincenzo Bonifati
Novel parkin mutations detected in patients with early-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2005;20(4):424-31.
2005: Jacqueline J M Assink; Caroline C W Klaver; Jeanine J Houwing-Duistermaat; Roger Wolfs; C.M. Duijn; Albert Hofman; Paulus T V M de Jong
Heterogeneity of the genetic risk in age-related macular disease: a population-based familial risk study.
Ophthalmology 2005;112(3):482-7.
2005: Yurii Aulchenko; Aida M Bertoli Avella; C.M. Duijn
A method for pooling alleles from different genotyping experiments.
Annals of human genetics 2005;69(Pt 2):233-8.
2005: Gysèle S Bleumink; A F C Schut; Miriam C J M Sturkenboom; C.M. Duijn; Jaap Deckers; Albert Hofman; J Herre Kingma; Jacqueline C M Witteman; Bruno H Ch Stricker
Mortality in patients with hypertension on angiotensin-I converting enzyme (ACE)-inhibitor treatment is influenced by the ACE insertion/deletion polymorphism.
Pharmacogenetics and genomics 2005;15(2):75-81.
2005: Loes E Visser; Paul H Trienekens; Peter A G M de Smet; Arnold G Vulto; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker
Patients with an ApoE epsilon4 allele require lower doses of coumarin anticoagulants.
Pharmacogenetics and genomics 2005;15(2):69-74.
2005: Gysèle S Bleumink; A F C Schut; Miriam C J M Sturkenboom; Joop A M J L Janssen; Jacqueline C M Witteman; C.M. Duijn; Albert Hofman; Bruno H Ch Stricker
A promoter polymorphism of the insulin-like growth factor-I gene is associated with left ventricular hypertrophy.
Heart (British Cardiac Society) 2005;91(2):239-40.
2005: Tine Venken; Stephan J Claes; Sam Sluijs; Andrew D Paterson; C.M. Duijn; Rolf Adolfsson; Jurgen Del-Favero; Christine Van Broeckhoven
Genomewide scan for affective disorder susceptibility Loci in families of a northern Swedish isolated population.
American journal of human genetics 2005;76(2):237-48.
2005: Esther A Croes; Rachid El Galta; Jeanine J Houwing-Duistermaat; Robert F Ferdinand; Sandra López León; Tessa Rademaker-Havinga; Marieke C J Dekker; Ben A Oostra; Frank C Verhulst; C.M. Duijn
Phenotypic subtypes in attention deficit hyperactivity disorder in an isolated population.
European journal of epidemiology 2005;20(9):789-94.
2005: M J E van Rijn; C.M. Duijn; A J C Slooter
Impact of genetic testing on complex diseases.
European journal of epidemiology 2005;20(5):383-8.
2005: Fakhredin A Sayed-Tabatabaei; A F C Schut; A Arias Vásquez; Aida M Bertoli Avella; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn
Angiotensin converting enzyme gene polymorphism and cardiovascular morbidity and mortality: the Rotterdam Study.
Journal of medical genetics 2005;42(1):26-30.
2004: Alejandro Arias Vásquez; Kristel Sleegers; Marieke C J Dekker; Willem A van Gool; John C van Swieten; Yurii Aulchenko; Ben A Oostra; C.M. Duijn
A deletion in DJ-1 and the risk of dementia--a population-based survey.
Neuroscience letters 2004;372(3):196-9.
2004: A F C Schut; Gysèle S Bleumink; Bruno H Ch Stricker; Albert Hofman; Jacqueline C M Witteman; Huibert A P Pols; Jaap Deckers; jaap deinum; C.M. Duijn
Angiotensin converting enzyme insertion/deletion polymorphism and the risk of heart failure in hypertensive subjects.
European heart journal 2004;25(23):2143-8.
2004: Tischa J M van der Cammen; Esther A Croes; Bart Dermaut; Marie-Claire de Jager; Marc Cruts; Christine Van Broeckhoven; C.M. Duijn
Genetic testing has no place as a routine diagnostic test in sporadic and familial cases of Alzheimer's disease.
Journal of the American Geriatrics Society 2004;52(12):2110-3.
2004: Marieke C J Dekker; Silvia Eshuis; R P Maguire; L Veenma-van der Duijn; Jan Pruim; Pieter J L M Snijders; Ben A Oostra; C.M. Duijn; Klaus L Leenders
PET neuroimaging and mutations in the DJ-1 gene.
Journal of neural transmission (Vienna, Austria : 1996) 2004;111(12):1575-81.
2004: Tom Den Heijer; Stephanie C E Schuit; Huibert A P Pols; Joyce B J van Meurs; Albert Hofman; Peter J Koudstaal; C.M. Duijn; André G Uitterlinden; Monique Breteler
Variations in estrogen receptor alpha gene and risk of dementia, and brain volumes on MRI.
Molecular psychiatry 2004;9(12):1129-35.
2004: Karin Geleijns; B A Brouwer; Bart C Jacobs; Jeanine J Houwing-Duistermaat; C.M. Duijn; Pieter A Van Doorn
The occurrence of Guillain-Barre syndrome within families.
Neurology 2004;63(9):1747-50.
2004: Gysèle S Bleumink; A F C Schut; Miriam C J M Sturkenboom; Jaap Deckers; C.M. Duijn; Bruno H Ch Stricker
Genetic polymorphisms and heart failure.
Genetics in medicine : official journal of the American College of Medical Genetics 2004;6(6):465-74.
2004: Helena Schmidt; Yurii Aulchenko; Natascha Schweighofer; Reinhold Schmidt; Sasa Frank; Gerhard Kostner; Erwin Ott; C.M. Duijn
Angiotensinogen promoter B-haplotype associated with cerebral small vessel disease enhances basal transcriptional activity.
Stroke; a journal of cerebral circulation 2004;35(11):2592-7.
2004: Pieter F A de Nijs; Robert F Ferdinand; Esther I de Bruin; Marieke C J Dekker; C.M. Duijn; Duijn C Verhulst
Attention-deficit/hyperactivity disorder (ADHD): parents' judgment about school, teachers' judgment about home.
European child & adolescent psychiatry 2004;13(5):315-20.
2004: Tom Den Heijer; Sarah E Vermeer; Ewoud J van Dijk; Niels D Prins; Peter J Koudstaal; C.M. Duijn; Albert Hofman; Monique Breteler
Alcohol intake in relation to brain magnetic resonance imaging findings in older persons without dementia.
The American journal of clinical nutrition 2004;80(4):992-7.
2004: Maurizio Pocchiari; Maria Puopolo; Esther Croes; Herbert Budka; Ellen Gelpi; Steven Collins; V Lewis; T Sutcliffe; A Guilivi; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; A Alperovitch; Inga Zerr; Sigrid Poser; Hans A Kretzschmar; Anna Ladogana; I Rietvald; Eva Mitrova; P Martinez-Martin; Jesús de Pedro-Cuesta; Markus Glatzel; Adriano Aguzzi; S Cooper; J Mackenzie; C.M. Duijn; Robert G Will
Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.
Brain : a journal of neurology 2004;127(Pt 10):2348-59.
2004: Marieke C J Dekker; R J H Galjaard; Pieter J L M Snijders; Peter Heutink; Ben A Oostra; C.M. Duijn
Brachydactyly and short stature in a kindred with early-onset parkinsonism.
American journal of medical genetics. Part A 2004;130A(1):102-4.
2004: Bengt Winblad; K Palmer; Miia Kivipelto; Vesna Jelic; Laura Fratiglioni; Lars-Olof Wahlund; agneta nordberg; Lars Bäckman; Marilyn S Albert; O Almkvist; Hiroyuki Arai; Hans Basun; Kaj Blennow; Mony J de Leon; Charles DeCarli; Timo Erkinjuntti; Ezio Giacobini; C Graff; John Hardy; C Jack; A Jorm; K Ritchie; C.M. Duijn; P Visser; Ronald C. Petersen
Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment.
Journal of internal medicine 2004;256(3):240-6.
2004: C.M. Duijn
Prospects of genetic research of mild cognitive impairment.
Journal of internal medicine 2004;256(3):235-9.
2004: Mariette W C J Schoofs; Marjolein Van der Klift; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker; Huibert A P Pols; André G Uitterlinden
ApoE gene polymorphisms, BMD, and fracture risk in elderly men and women: the Rotterdam study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(9):1490-6.
2004: Behrooz Alizadeh; Omer T Njajou; Jeanine J Houwing-Duistermaat; Gerard de Jong; Jeannette M Vergeer; Albert Hofman; Huibert A P Pols; C.M. Duijn
Does bilirubin protect against hemochromatosis gene (HFE) related mortality?
American journal of medical genetics. Part A 2004;129A(1):39-43.
2004: Aaron Isaacs; Fakhredin A Sayed-Tabatabaei; Omer T Njajou; Jacqueline C M Witteman; C.M. Duijn
The -514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis.
The Journal of clinical endocrinology and metabolism 2004;89(8):3858-63.
2004: M P W A Houben; W J Louwman; Cees C Tijssen; J L J M Teepen; C.M. Duijn; Dorry Boll
Hypertension as a risk factor for glioma? Evidence from a population-based study of comorbidity in glioma patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(8):1256-60.
2004: Gysèle S Bleumink; Ingrid Rietveld; Joop A M J L Janssen; Elisabeth F C van Rossum; Jaap Deckers; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn; Bruno H Ch Stricker
Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study).
The American journal of cardiology 2004;94(3):384-6.
2004: Ingrid Rietveld; Joop A M J L Janssen; Elisabeth F C van Rossum; Jeanine J Houwing-Duistermaat; Fernando Rivadeneira; Albert Hofman; Huibert A P Pols; C.M. Duijn; Steven W J Lamberts
A polymorphic CA repeat in the IGF-I gene is associated with gender-specific differences in body height, but has no effect on the secular trend in body height.
Clinical endocrinology 2004;61(2):195-203.
2004: Anke Hilse Maitland-van der Zee; Olaf Klungel; Hubert G M Leufkens; Anthonius de Boer; Bruno H Ch Stricker; Albert Hofman; Jacqueline C M Witteman; C.M. Duijn; John J P Kastelein
Effectiveness of HMG-CoA reductase inhibitors is modified by the ACE insertion deletion polymorphism.
Atherosclerosis 2004;175(2):377-9.
2004: Esther A Croes; Jessie Theuns; Jeanine J Houwing-Duistermaat; Bart Dermaut; Kristel Sleegers; Gerwin Roks; Marleen Van den Broeck; B van Harten; John C van Swieten; Marc Cruts; Christine Van Broeckhoven; C.M. Duijn
Octapeptide repeat insertions in the prion protein gene and early onset dementia.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1166-70.
2004: Fernando Rivadeneira; Jeanine J Houwing-Duistermaat; Thomas J Beck; Joop A M J L Janssen; Albert Hofman; Huibert A P Pols; C.M. Duijn; André G Uitterlinden
The influence of an insulin-like growth factor I gene promoter polymorphism on hip bone geometry and the risk of nonvertebral fracture in the elderly: the Rotterdam Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2004;19(8):1280-90.
2004: Loes E Visser; Ron van Schaik; Martin van Vliet; Paul H Trienekens; Peter A G M de Smet; Arnold G Vulto; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker
The risk of bleeding complications in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
Thrombosis and haemostasis 2004;92(1):61-6.
2004: Kristel Sleegers; Gerwin Roks; Jessie Theuns; Yurii Aulchenko; Rosa Rademakers; Marc Cruts; Willem A van Gool; Christine Van Broeckhoven; Peter Heutink; Ben A Oostra; John C van Swieten; C.M. Duijn
Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.
Brain : a journal of neurology 2004;127(Pt 7):1641-9.
2004: Yurii Aulchenko; Peter Heutink; Ian Mackay; Aida M Bertoli Avella; Jan Pullen; Norbert Vaessen; Tessa Rademaker-Havinga; Lodewijk A Sandkuijl; Lon Cardon; Ben A Oostra; C.M. Duijn
Linkage disequilibrium in young genetically isolated Dutch population.
European journal of human genetics : EJHG 2004;12(7):527-34.
2004: Francesco U S Mattace-Raso; Tischa J M van der Cammen; Fakhredin A Sayed-Tabatabaei; Nicole M van Popele; Roland Asmar; Maarten A D H Schalekamp; Albert Hofman; C.M. Duijn; Jacqueline C M Witteman
Angiotensin-converting enzyme gene polymorphism and common carotid stiffness. The Rotterdam study.
Atherosclerosis 2004;174(1):121-6.
2004: G Zhai; Fernando Rivadeneira; Jeanine J Houwing-Duistermaat; Ingrid Meulenbelt; C Bijkerk; Albert Hofman; Joyce B J van Meurs; André G Uitterlinden; Huibert A P Pols; P Eline Slagboom; C.M. Duijn
Insulin-like growth factor I gene promoter polymorphism, collagen type II alpha1 (COL2A1) gene, and the prevalence of radiographic osteoarthritis: the Rotterdam Study.
Annals of the rheumatic diseases 2004;63(5):544-8.
2004: Frank-Erik De Leeuw; Florence Richard; John C M J de Groot; C.M. Duijn; Albert Hofman; Jan van Gijn; Monique Breteler
Interaction between hypertension, apoE, and cerebral white matter lesions.
Stroke; a journal of cerebral circulation 2004;35(5):1057-60.
2004: Esther A Croes; Behrooz Alizadeh; Aida M Bertoli Avella; Tessa Rademaker-Havinga; Jeannette Vergeer-Drop; Bart Dermaut; Jeanine J Houwing-Duistermaat; Dorothee P W M Wientjens; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn
Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease.
European journal of human genetics : EJHG 2004;12(5):389-94.
2004: A J C Slooter; Marc Cruts; Albert Hofman; Peter J Koudstaal; Deirdre A M van der Kuip; Maria A J de Ridder; Jacqueline C M Witteman; Monique Breteler; Christine Van Broeckhoven; C.M. Duijn
The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study.
Neurology 2004;62(7):1196-8.
2004: Ingrid Meulenbelt; Albert B Seymour; Marja Nieuwland; Tom W J Huizinga; C.M. Duijn; P Eline Slagboom
Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip.
Arthritis and rheumatism 2004;50(4):1179-86.
2004: Gysèle S Bleumink; C.M. Duijn; J Herre Kingma; Jacqueline C M Witteman; Albert Hofman; Bruno H Ch Stricker
Apolipoprotein E epsilon4 allele is associated with left ventricular systolic dysfunction.
American heart journal 2004;147(4):685-9.
2004: Redmer van Leeuwen; Caroline C W Klaver; Johannes Vingerling; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker; Paulus T V M de Jong
Cholesterol and age-related macular degeneration: is there a link?
American journal of ophthalmology 2004;137(4):750-2.
2004: Ewoud J van Dijk; Niels D Prins; Sarah E Vermeer; Albert Hofman; C.M. Duijn; Peter J Koudstaal; Monique Breteler
Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions.
Annals of neurology 2004;55(4):570-5.
2004: Dirk van West; Jurgen Del-Favero; Yurii Aulchenko; Pierre Oswald; Daniel Souery; Thomas Forsgren; Sam Sluijs; Samira Bel Kacem; Rolf Adolfsson; Julien Mendlewicz; C.M. Duijn; Dirk Deboutte; Christine Van Broeckhoven; Stephan J Claes
A major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression.
Molecular psychiatry 2004;9(3):287-92.
2004: A Cecile J W Janssens; M Carolina Pardo; Ewout W Steyerberg; C.M. Duijn
Revisiting the clinical validity of multiplex genetic testing in complex diseases.
American journal of human genetics 2004;74(3):585-8; author reply 588-9.
2004: A F C Schut; Fakhredin A Sayed-Tabatabaei; Jacqueline C M Witteman; Aida M Bertoli Avella; Jeannette M Vergeer; Huibert A P Pols; Albert Hofman; jaap deinum; C.M. Duijn
Smoking-dependent effects of the angiotensin-converting enzyme gene insertion/deletion polymorphism on blood pressure.
Journal of hypertension 2004;22(2):313-9.
2004: Fakhredin A Sayed-Tabatabaei; A F C Schut; Albert Hofman; Aida M Bertoli Avella; Jeannette M Vergeer; Jacqueline C M Witteman; C.M. Duijn
A study of gene--environment interaction on the gene for angiotensin converting enzyme: a combined functional and population based approach.
Journal of medical genetics 2004;41(2):99-103.
2004: Leen M 't Hart; Andreas Fritsche; Ingrid Rietveld; Jacqueline M Dekker; Giel Nijpels; Fausto Machicao; Michael Stumvoll; C.M. Duijn; Hans-Ulrich Häring; Robert J Heine; J Antonie Maassen; Timon W van Haeften
Genetic factors and insulin secretion: gene variants in the IGF genes.
Diabetes 2004;53 Suppl 1():S26-30.
2004: Rosa Rademakers; Marleen Van den Broeck; Kristel Sleegers; C.M. Duijn; Christine Van Broeckhoven; Marc Cruts
Absence of pathogenic mutations in presenilin homologue 2 in a conclusively 17-linked tau-negative dementia family.
Neurogenetics 2004;5(1):79-80.
2004: Hedi Schelleman; Bruno H Ch Stricker; Anthonius de Boer; Abraham A Kroon; Monique W M Verschuren; C.M. Duijn; Bruce M Psaty; Olaf Klungel
Drug-gene interactions between genetic polymorphisms and antihypertensive therapy.
Drugs 2004;64(16):1801-16.
2004: Anke Hilse Maitland-van der Zee; Olaf Klungel; Bruno H Ch Stricker; David L Veenstra; John J P Kastelein; Albert Hofman; Jacqueline C M Witteman; Hubert G M Leufkens; C.M. Duijn; Anthonius de Boer
Pharmacoeconomic evaluation of testing for angiotensin-converting enzyme genotype before starting beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitor therapy in men.
Pharmacogenetics 2004;14(1):53-60.
2004: Loes E Visser; Martin van Vliet; Ron van Schaik; A A Harrie Kasbergen; Peter A G M de Smet; Arnold G Vulto; Albert Hofman; C.M. Duijn; Bruno H Ch Stricker
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon.
Pharmacogenetics 2004;14(1):27-33.
2004: Omer T Njajou; Behrooz Alizadeh; C.M. Duijn
Is genetic screening for hemochromatosis worthwhile?
European journal of epidemiology 2004;19(2):101-8.
2003: Yurii Aulchenko; Norbert Vaessen; Peter Heutink; Jan Pullen; Pieter J L M Snijders; Albert Hofman; Lodewijk A Sandkuijl; Jeanine J Houwing-Duistermaat; Mark Edwards; Simon Bennett; Ben A Oostra; C.M. Duijn
A genome-wide search for genes involved in type 2 diabetes in a recently genetically isolated population from the Netherlands.
Diabetes 2003;52(12):3001-4.
2003: Aida M Bertoli Avella; Jose L Giroud-Benitez; Vincenzo Bonifati; Eduardo Alvarez-Gonzalez; Luis Heredero-Baute; C.M. Duijn; Peter Heutink
Suggestive linkage to chromosome 19 in a large Cuban family with late-onset Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2003;18(11):1240-9.
2003: Sonia M Rosso; E-J Landweer; M Houterman; L Donker Kaat; C.M. Duijn; John C van Swieten
Medical and environmental risk factors for sporadic frontotemporal dementia: a retrospective case-control study.
Journal of neurology, neurosurgery, and psychiatry 2003;74(11):1574-6.
2003: Vincenzo Bonifati; Patrizia Rizzu; Ferdinando Squitieri; Elmar Krieger; Nicola Vanacore; John C van Swieten; Alexis Brice; C.M. Duijn; Ben A Oostra; Giuseppe Meco; Peter Heutink
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2003;24(3):159-60.
2003: Marieke C J Dekker; Patricia C Giesbergen; Omer T Njajou; John C van Swieten; Albert Hofman; Monique Breteler; C.M. Duijn
Mutations in the hemochromatosis gene (HFE), Parkinson's disease and parkinsonism.
Neuroscience letters 2003;348(2):117-9.
2003: Marieke C J Dekker; John C van Swieten; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; E Boeren; Albert Hofman; Monique Breteler; Peter Heutink; Ben A Oostra; C.M. Duijn
A clinical-genetic study of Parkinson's disease in a genetically isolated community.
Journal of neurology 2003;250(9):1056-62.
2003: Yue Fang; Joyce B J van Meurs; Arjan P Bergink; Albert Hofman; C.M. Duijn; Johannes P T M van Leeuwen; Huibert A P Pols; André G Uitterlinden
Cdx-2 polymorphism in the promoter region of the human vitamin D receptor gene determines susceptibility to fracture in the elderly.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2003;18(9):1632-41.
2003: Jeanine J Houwing-Duistermaat; C Bijkerk; L Hsu; Theo Stijnen; Eline Slagboom; C.M. Duijn
A unified approach to modelling linkage to quantitative and qualitative traits.
Annals of human genetics 2003;67(Pt 5):457-63.
2003: Sonia M Rosso; Laura Donker Kaat; Timo Baks; Marijke Joosse; Inge de Koning; Y A L Pijnenburg; Danielle De Jong; Dennis Dooijes; Wouter Kamphorst; Rivka Ravid; Martinus F Niermeijer; Frans Verheij; H P H Kremer; Philip scheltens; C.M. Duijn; Peter Heutink; John C van Swieten
Frontotemporal dementia in The Netherlands: patient characteristics and prevalence estimates from a population-based study.
Brain : a journal of neurology 2003;126(Pt 9):2016-22.
2003: Fernando Rivadeneira; Jeanine J Houwing-Duistermaat; Norbert Vaessen; Jeannette M Vergeer-Drop; Albert Hofman; Huibert A P Pols; C.M. Duijn; André G Uitterlinden
Association between an insulin-like growth factor I gene promoter polymorphism and bone mineral density in the elderly: the Rotterdam Study.
The Journal of clinical endocrinology and metabolism 2003;88(8):3878-84.
2003: Esther A Croes; Bart Dermaut; Jeanine J Houwing-Duistermaat; Marleen Van den Broeck; Marc Cruts; Monique Breteler; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn
Early cognitive decline is associated with prion protein codon 129 polymorphism.
Annals of neurology 2003;54(2):275-6.
2003: Marieke C J Dekker; Vincenzo Bonifati; C.M. Duijn
Parkinson's disease: piecing together a genetic jigsaw.
Brain : a journal of neurology 2003;126(Pt 8):1722-33.
2003: Joyce B J van Meurs; Stephanie C E Schuit; A E A M Weel; Marjolein Van der Klift; Arjan P Bergink; Pascal P Arp; Edgar M Colin; Yue Fang; Albert Hofman; C.M. Duijn; Johannes P T M van Leeuwen; Huibert A P Pols; André G Uitterlinden
Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk.
Human molecular genetics 2003;12(14):1745-54.
2003: Yurii Aulchenko; Tatiana I Axenovich; Ian Mackay; C.M. Duijn
miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium.
Annals of human genetics 2003;67(Pt 4):372-5.
2003: Arjan P Bergink; Joyce B J van Meurs; John Loughlin; Pascal P Arp; Yue Fang; Albert Hofman; Johannes P T M van Leeuwen; C.M. Duijn; André G Uitterlinden; Huibert A P Pols
Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women.
Arthritis and rheumatism 2003;48(7):1913-22.
2003: Marieke C J Dekker; Vincenzo Bonifati; John C van Swieten; Nico Leenders; R J H Galjaard; Pieter J L M Snijders; Martin Horstink; Peter Heutink; Ben A Oostra; C.M. Duijn
Clinical features and neuroimaging of PARK7-linked parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2003;18(7):751-7.
2003: Fakhredin A Sayed-Tabatabaei; Jeanine J Houwing-Duistermaat; C.M. Duijn; Jacqueline C M Witteman
Angiotensin-converting enzyme gene polymorphism and carotid artery wall thickness: a meta-analysis.
Stroke; a journal of cerebral circulation 2003;34(7):1634-9.
2003: A F C Schut; Joop A M J L Janssen; jaap deinum; Jeannette M Vergeer; Albert Hofman; Steven W J Lamberts; Ben A Oostra; Huibert A P Pols; Jacqueline C M Witteman; C.M. Duijn
Polymorphism in the promoter region of the insulin-like growth factor I gene is related to carotid intima-media thickness and aortic pulse wave velocity in subjects with hypertension.
Stroke; a journal of cerebral circulation 2003;34(7):1623-7.
2003: Anke Hilse Maitland-van der Zee; Bruno H Ch Stricker; Olaf Klungel; Aukje K Mantel-Teeuwisse; John J P Kastelein; Albert Hofman; Hubert G M Leufkens; C.M. Duijn; Anthonius de Boer
Adherence to and dosing of beta-hydroxy-beta-methylglutaryl coenzyme A reductase inhibitors in the general population differs according to apolipoprotein E-genotypes.
Pharmacogenetics 2003;13(4):219-23.
2003: Omer T Njajou; Jeanine J Houwing-Duistermaat; Richard H Osborne; Norbert Vaessen; Jeannette M Vergeer; Jan Heeringa; Huibert A P Pols; Albert Hofman; C.M. Duijn
A population-based study of the effect of the HFE C282Y and H63D mutations on iron metabolism.
European journal of human genetics : EJHG 2003;11(3):225-31.
2003: Bart Dermaut; Esther A Croes; Rosa Rademakers; Marleen Van den Broeck; Marc Cruts; Albert Hofman; C.M. Duijn; Christine Van Broeckhoven
PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease.
Annals of neurology 2003;53(3):409-12.
2003: Ingrid Rietveld; Joop A M J L Janssen; Albert Hofman; Huibert A P Pols; C.M. Duijn; Steven W J Lamberts
A polymorphism in the IGF-I gene influences the age-related decline in circulating total IGF-I levels.
European journal of endocrinology / European Federation of Endocrine Societies 2003;148(2):171-5.
2003: Vincenzo Bonifati; Patrizia Rizzu; Marijke J van Baren; Onno Schaap; Guido J Breedveld; Elmar Krieger; Marieke C J Dekker; Ferdinando Squitieri; Pablo Ibanez; Marijke Joosse; Jeroen W F van Dongen; Nicola Vanacore; John C van Swieten; Alexis Brice; Giuseppe Meco; C.M. Duijn; Ben A Oostra; Peter Heutink
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Science (New York, N.Y.) 2003;299(5604):256-9.
2003: Marieke C J Dekker; C.M. Duijn
Prospects of genetic epidemiology in the 21st century.
European journal of epidemiology 2003;18(7):607-16.
2003: Esther A Croes; C.M. Duijn
Variant Creutzfeldt-Jakob disease.
European journal of epidemiology 2003;18(6):473-7.
2003: C.M. Duijn; Miquel Porta
Good prospects for genetic and molecular epidemiologic studies in the European Journal of Epidemiology.
European journal of epidemiology 2003;18(4):285-6.
2003: Omer T Njajou; Behrooz Alizadeh; C.M. Duijn
Genetic screening for common mutations: lessons from hereditary hemochromatosis.
European journal of epidemiology 2003;18(1):3-4.
2002: Linda B Johnston; N J T Arends; Jovanna Dahlgren; Juliane Leger; Paul Czernichow; Kerstin Albertsson-Wikland; C.M. Duijn; Anita C S Hokken-Koelega; Martin O Savage; Adrian J L Clark
Gene association studies in small for gestational age infants.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15 Suppl 5():1459.
2002: Caroline A A Hulsman; Jeanine J Houwing-Duistermaat; C.M. Duijn; Roger Wolfs; Petra H Borger; Albert Hofman; Paulus T V M de Jong
Family score as an indicator of genetic risk of primary open-angle glaucoma.
Archives of ophthalmology 2002;120(12):1726-31.
2002: Omer T Njajou; Gerard de Jong; Bianca Berghuis; Norbert Vaessen; Pieter J L M Snijders; Jan P Goossens; John H P Wilson; Martijn H Breuning; Ben A Oostra; Peter Heutink; Lodewijk A Sandkuijl; C.M. Duijn
Dominant hemochromatosis due to N144H mutation of SLC11A3: clinical and biological characteristics.
Blood cells, molecules & diseases 2002;29(3):439-43.
2002: Anke Hilse Maitland-van der Zee; Bruno H Stricker; Olaf Klungel; John J Kastelein; Albert Hofman; Jacqueline C M Witteman; Monique Breteler; Hubertus G Leufkens; C.M. Duijn; Anthonius de Boer
The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype.
Pharmacogenetics 2002;12(8):647-53.
2002: Omer T Njajou; Behrooz Alizadeh; Norbert Vaessen; Jeannette M Vergeer; Jeanine J Houwing-Duistermaat; Albert Hofman; Huibert A P Pols; C.M. Duijn
The role of hemochromatosis C282Y and H63D gene mutations in type 2 diabetes: findings from the Rotterdam Study and meta-analysis.
Diabetes care 2002;25(11):2112-3.
2002: Ilya Chumakov; Marta Blumenfeld; Oxana Guerassimenko; Laurent Cavarec; Marta Palicio; Hadi Abderrahim; Lydie Bougueleret; Caroline Barry; Hiroaki Tanaka; Philippe La Rosa; Anne Puech; Nadia Tahri; Annick Cohen-Akenine; Sylvain Delabrosse; Sébastien Lissarrague; Françoise-Pascaline Picard; Karelle Maurice; Laurent Essioux; Philippe Millasseau; Pascale Grel; Virginie Debailleul; Anne-Marie Simon; Dominique Caterina; Isabelle Dufaure; Kattayoun Malekzadeh; Maria Belova; Jian-Jian Luan; Michel Bouillot; Jean-Luc Sambucy; Gwenael Primas; Martial Saumier; Nadia Boubkiri; Sandrine Martin-Saumier; Myriam Nasroune; Hélène Peixoto; Arnaud Delaye; Virginie Pinchot; Mariam Bastucci; Sophie Guillou; Magali Chevillon; Ricardo Sainz Fuertes; Said Meguenni; Joan Aurich-Costa; Dorra Cherif; Anne Gimalac; C.M. Duijn; Denis Gauvreau; Gail Ouellette; Isabel Fortier; John Raelson; Tatiana Sherbatich; Nadejda Riazanskaia; Evgeny I Rogaev; Peter Raeymaekers; Jeroen Aerssens; Frank Konings; Walter Luyten; Fabio Macciardi; Pak C Sham; Richard E Straub; Daniel R Weinberger; Nadine Cohen; Daniel Cohen; Gail Ouelette; John Realson
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13675-80.
2002: Aida M Bertoli Avella; B Marcheco Teruel; J J Llibre Rodriguez; N Gomez Viera; I Borrajero Martinez; E A Severijnen; Marijke Joosse; C.M. Duijn; Luis Heredero-Baute; Peter Heutink
A novel presenilin 1 mutation (L174 M) in a large Cuban family with early onset Alzheimer disease.
Neurogenetics 2002;4(2):97-104.
2002: Omer T Njajou; Monika Hollander; Peter J Koudstaal; Albert Hofman; Jacqueline C M Witteman; Monique Breteler; C.M. Duijn
Mutations in the hemochromatosis gene (HFE) and stroke.
Stroke; a journal of cerebral circulation 2002;33(10):2363-6.
2002: Tom Den Heijer; Matthijs Oudkerk; Lenore J Launer; C.M. Duijn; Albert Hofman; Monique Breteler
Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes.
Neurology 2002;59(5):746-8.
2002: Vincenzo Bonifati; Marieke C J Dekker; Nicola Vanacore; Giovanni Fabbrini; Ferdinando Squitieri; Roberto Marconi; Angelo Antonini; P Brustenghi; A Dalla Libera; Michele De Mari; Fabrizio Stocchi; P Montagna; V Gallai; Patrizia Rizzu; John C van Swieten; Ben A Oostra; C.M. Duijn; Giuseppe Meco; Peter Heutink
Autosomal recessive early onset parkinsonism is linked to three loci: PARK2, PARK6, and PARK7.
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2002;23 Suppl 2():S59-60.
2002: H J T Ward; Dawn Everington; Esther Croes; A Alperovitch; Nicole Delasnerie-Lauprêtre; Inga Zerr; Sigrid Poser; C.M. Duijn
Sporadic Creutzfeldt-Jakob disease and surgery: a case-control study using community controls.
Neurology 2002;59(4):543-8.
2002: Samir Kumar-Singh; Patrick Cras; Rong Wang; John M Kros; John C van Swieten; Ursula Lübke; Chantal Ceuterick; Sally Serneels; Krist'l Vennekens; Jean-Pierre Timmermans; Eric Van Marck; Jean-Jacques Martin; C.M. Duijn; Christine Van Broeckhoven
Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric.
The American journal of pathology 2002;161(2):507-20.
2002: Gerwin Roks; Marc Cruts; Jeanine J Houwing-Duistermaat; Bart Dermaut; Sally Serneels; L M Havekes; Albert Hofman; Monique Breteler; Christine Van Broeckhoven; C.M. Duijn
Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study.
American journal of medical genetics 2002;114(5):570-3.
2002: Caroline A A Hulsman; Paulus T V M de Jong; Marjolein Lettink; C.M. Duijn; Albert Hofman; Arthur A B Bergen
Myocilin mutations in a population-based sample of cases with open-angle glaucoma: the Rotterdam Study.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2002;240(6):468-74.
2002: N J T Arends; Linda Johnston; Anita C S Hokken-Koelega; C.M. Duijn; Maria A J de Ridder; Martin Savage; Adrian Clark
Polymorphism in the IGF-I gene: clinical relevance for short children born small for gestational age (SGA).
The Journal of clinical endocrinology and metabolism 2002;87(6):2720.
2002: S M Rosso; Gerwin Roks; Marc Cruts; Christine Van Broeckhoven; Peter Heutink; C.M. Duijn; John C van Swieten
Apolipoprotein E4 in the temporal variant of frontotemporal dementia.
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):820.
2002: Esther A Croes; Gerwin Roks; Gerard H Jansen; Peter Nijssen; C.M. Duijn
Creutzfeldt-Jakob disease 38 years after diagnostic use of human growth hormone.
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):792-3.
2002: Herbert Budka; Dominique Dormont; Hans A Kretzschmar; Maurizio Pocchiari; C.M. Duijn
BSE and variant Creutzfeldt-Jakob disease: never say never.
Acta neuropathologica 2002;103(6):627-8.
2002: Bart Dermaut; Jessie Theuns; Kristel Sleegers; Hiroshi Hasegawa; Marleen Van den Broeck; Krist'l Vennekens; Ellen Corsmit; Peter St George-Hyslop; Marc Cruts; C.M. Duijn; Christine Van Broeckhoven
The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample.
American journal of human genetics 2002;70(6):1568-74.
2002: A J C Slooter; Gerwin Roks; C.M. Duijn
Genetic association studies: genes in search of diseases.
Neurology 2002;58(10):1577.
2002: Hanne Meijers-Heijboer; Ans van den Ouweland; Jan Klijn; Marijke Wasielewski; Anja de Snoo; Rogier Oldenburg; Antoinette Hollestelle; Mark Houben; Ellen Crepin; Monique van Veghel-Plandsoen; Fons Elstrodt; C.M. Duijn; Carina Bartels; Carel Meijers; Mieke Schutte; Lesley McGuffog; Deborah Thompson; Douglas Easton; Nayanta Sodha; Sheila Seal; Rita Barfoot; Jon Mangion; Jenny Chang-Claude; Diana Eccles; Rosalind Eeles; D Gareth Evans; Richard Houlston; Victoria Murday; steven narod; Tamara Peretz; Julian Peto; Catherine Phelan; Hong Xiang Zhang; Csilla Szabo; Peter Devilee; David Goldgar; P Andrew Futreal; Katherine L Nathanson; Barbara Weber; Nazneen Rahman; Michael R Stratton
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations.
Nature genetics 2002;31(1):55-9.
2002: Esther A Croes; Willem A van Gool; Gerard H Jansen; C.M. Duijn
[Creutzfeldt-Jakob disease: diagnosis, incidence, prevention and treatment].
Nederlands tijdschrift voor geneeskunde 2002;146(16):750-4.
2002: Norbert Vaessen; Joop A M J L Janssen; Peter Heutink; Albert Hofman; Steven W J Lamberts; Ben A Oostra; Huibert A P Pols; C.M. Duijn
Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight.
Lancet 2002;359(9311):1036-7.
2002: Esther A Croes; Tischa J M van der Cammen; Kristel Sleegers; C.M. Duijn
[From gene to disease; presenilins and Alzheimer disease].
Nederlands tijdschrift voor geneeskunde 2002;146(10):494-5; author reply 495.
2002: Omer T Njajou; Norbert Vaessen; Ben A Oostra; Peter Heutink; C.M. Duijn
The hemochromatosis N144H mutation of SLC11A3 gene in patients with type 2 diabetes.
Molecular genetics and metabolism 2002;75(3):290-1.
2002: Norbert Vaessen; Peter Heutink; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; Tessa Rademaker-Havinga; Leon Testers; Manou R Batstra; Lodewijk A Sandkuijl; C.M. Duijn; Ben A Oostra
A genome-wide search for linkage-disequilibrium with type 1 diabetes in a recent genetically isolated population from the Netherlands.
Diabetes 2002;51(3):856-9.
2002: Vincenzo Bonifati; Guido J Breedveld; Ferdinando Squitieri; Nicola Vanacore; Pierluigi Brustenghi; Biswadjiet S Harhangi; Pasquale Montagna; Milena Cannella; Giovanni Fabbrini; Patrizia Rizzu; C.M. Duijn; Ben A Oostra; Giuseppe Meco; Peter Heutink
Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset.
Annals of neurology 2002;51(2):253-6.
2002: Femke de Beer; Anton F H Stalenhoef; Nicoline Hoogerbrugge; John J P Kastelein; Jan A Gevers Leuven; C.M. Duijn; Louis M Havekes; August Smelt
Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(2):294-9.
2002: Annemieke Ruitenberg; John C van Swieten; Jacqueline C M Witteman; Kala M Mehta; C.M. Duijn; Albert Hofman; Monique Breteler
Alcohol consumption and risk of dementia: the Rotterdam Study.
Lancet 2002;359(9303):281-6.
2002: J J Hottenga; Jeanine J Houwing-Duistermaat; C.M. Duijn
[Roaming through methodology. XXXVII. Unintentional population stratification in genetic case-control studies].
Nederlands tijdschrift voor geneeskunde 2002;146(1):17-22.
2002: Rosa Rademakers; Marc Cruts; Bart Dermaut; Kristel Sleegers; S M Rosso; Marleen Van den Broeck; Hubert Backhovens; John C van Swieten; C.M. Duijn; Christine Van Broeckhoven
Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval.
Molecular psychiatry 2002;7(10):1064-74.
2002: S Van Gestel; Thomas Forsgren; Stephan J Claes; Jurgen Del-Favero; C.M. Duijn; Sam Sluijs; Lars-Göran Nilsson; Rolf Adolfsson; Christine Van Broeckhoven
Epistatic effect of genes from the dopamine and serotonin systems on the temperament traits of novelty seeking and harm avoidance.
Molecular psychiatry 2002;7(5):448-50.
2001: Richard H Osborne; M P W A Houben; Cees C Tijssen; J W Coebergh; C.M. Duijn
The genetic epidemiology of glioma.
Neurology 2001;57(10):1751-5.
2001: Bas in 't veld; Annemieke Ruitenberg; Albert Hofman; Lenore J Launer; C.M. Duijn; Theo Stijnen; Monique Breteler; Bruno H Ch Stricker
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease.
The New England journal of medicine 2001;345(21):1515-21.
2001: Marc Cruts; Bart Dermaut; Rosa Rademakers; Gerwin Roks; Marleen Van den Broeck; G Munteanu; C.M. Duijn; Christine Van Broeckhoven
Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease.
Neuroscience letters 2001;313(1-2):105-7.
2001: Bart Van Everbroeck; Esther A Croes; Philippe Pals; Bart Dermaut; G Jansen; C.M. Duijn; Marc Cruts; Christine Van Broeckhoven; Jean-Jacques Martin; Patrick Cras
Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype.
Neuroscience letters 2001;313(1-2):69-72.
2001: Bart Dermaut; Gerwin Roks; Jessie Theuns; Rosa Rademakers; Jeanine J Houwing-Duistermaat; Sally Serneels; Albert Hofman; Monique Breteler; Marc Cruts; Christine Van Broeckhoven; C.M. Duijn
Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's disease.
Journal of neurology 2001;248(11):935-9.
2001: Anne M Cataldo; G. William Rebeck; B Ghetri; Christine M Hulette; Carol F Lippa; Christine Van Broeckhoven; C.M. Duijn; Patrick cras; Nenad Bogdanovic; Thomas D Bird; Corrinne M Peterhoff; Ralph A. Nixon
Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders.
Annals of neurology 2001;50(5):661-5.
2001: Esther A Croes; Gerard H Jansen; Afina W Lemstra; C J Frijns; Willem A van Gool; C.M. Duijn
The first two patients with dura mater associated Creutzfeldt-Jakob disease in the Netherlands.
Journal of neurology 2001;248(10):877-80.
2001: Cornelis Kramers; Sergei M Danilov; jaap deinum; Irina V Balyasnikova; Nicole M Scharenborg; Maaike W G Looman; F Boomsma; Marinus H de Keijzer; C.M. Duijn; S Martin; Florent Soubrier; Gosse J Adema
Point mutation in the stalk of angiotensin-converting enzyme causes a dramatic increase in serum angiotensin-converting enzyme but no cardiovascular disease.
Circulation 2001;104(11):1236-40.
2001: A J C Slooter; Michiel Bots; L M Havekes; Antonio Iglesias Del Sol; Marc Cruts; Diederick Grobbee; Albert Hofman; Christine Van Broeckhoven; Jacqueline C M Witteman; C.M. Duijn
Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam study.
Stroke; a journal of cerebral circulation 2001;32(9):1947-52.
2001: C.M. Duijn; Marieke C J Dekker; Vincenzo Bonifati; R J H Galjaard; Jeanine J Houwing-Duistermaat; Pieter J L M Snijders; Leon Testers; Guido J Breedveld; Martin Horstink; Lodewijk A Sandkuijl; John C van Swieten; Ben A Oostra; Peter Heutink
Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.
American journal of human genetics 2001;69(3):629-34.
2001: Gerwin Roks; Marc Cruts; A J C Slooter; Bart Dermaut; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn
The cystatin C polymorphism is not associated with early onset Alzheimer's disease.
Neurology 2001;57(2):366-7.
2001: Jonathan A Beck; simon mead; Tracy A Campbell; Andrew Dickinson; D P Wientjens; Esther A Croes; C.M. Duijn; John Collinge
Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia.
Neurology 2001;57(2):354-6.
2001: Omer T Njajou; Norbert Vaessen; Marijke Joosse; B Berghuis; Jeroen W F van Dongen; Martijn H Breuning; Pieter J L M Snijders; W P Rutten; Lodewijk A Sandkuijl; Ben A Oostra; C.M. Duijn; Peter Heutink
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis.
Nature genetics 2001;28(3):213-4.
2001: Jessie Theuns; Lars Feuk; Bart Dermaut; Jurgen Del-Favero; Gerwin Roks; Dirk Van den Bossche; Ellen Corsmit; Marleen Van den Broeck; C.M. Duijn; Marc Cruts; Anthony J Brookes; Christine Van Broeckhoven
The TNFRSF6 gene is not implicated in familial early-onset Alzheimer's disease.
Human genetics 2001;108(6):552-3.
2001: Paulus T V M de Jong; Arthur A B Bergen; Caroline C W Klaver; C.M. Duijn; J M Assink
Age-related maculopathy: its genetic basis.
Eye (London, England) 2001;15(Pt 3):396-400.
2001: Norbert Vaessen; C.M. Duijn
Opportunities for population-based studies of complex genetic disorders after the human genome project.
Epidemiology (Cambridge, Mass.) 2001;12(3):360-4.
2001: Mirjam I Geerlings; Annemieke Ruitenberg; Jacqueline C M Witteman; John C van Swieten; Albert Hofman; C.M. Duijn; Monique Breteler; Lenore J Launer
Reproductive period and risk of dementia in postmenopausal women.
JAMA : the journal of the American Medical Association 2001;285(11):1475-81.
2001: Biswadjiet S Harhangi; Ben A Oostra; Peter Heutink; C.M. Duijn; Albert Hofman; Monique Breteler
CYP2D6 polymorphism in Parkinson's disease: the Rotterdam Study.
Movement disorders : official journal of the Movement Disorder Society 2001;16(2):290-3.
2001: Norbert Vaessen; Peter Heutink; Joop A M J L Janssen; Jacqueline C M Witteman; Leon Testers; Albert Hofman; Steven W J Lamberts; Ben A Oostra; Huibert A P Pols; C.M. Duijn
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction.
Diabetes 2001;50(3):637-42.
2001: André G Uitterlinden; A E A M Weel; H Burger; Yue Fang; C.M. Duijn; Albert Hofman; Johannes P T M van Leeuwen; Huibert A P Pols
Interaction between the vitamin D receptor gene and collagen type Ialpha1 gene in susceptibility for fracture.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(2):379-85.
2001: Helena Schmidt; Franz Fazekas; Gerhard Kostner; C.M. Duijn; Reinhold Schmidt
Angiotensinogen gene promoter haplotype and microangiopathy-related cerebral damage: results of the Austrian Stroke Prevention Study.
Stroke; a journal of cerebral circulation 2001;32(2):405-12.
2000: Gerwin Roks; Frans van Harskamp; Inge de Koning; Marc Cruts; Chris De Jonghe; Samir Kumar-Singh; A Tibben; Hervé L J Tanghe; Martinus F Niermeijer; Albert Hofman; John C van Swieten; Christine Van Broeckhoven; C.M. Duijn
Presentation of amyloidosis in carriers of the codon 692 mutation in the amyloid precursor protein gene (APP692).
Brain : a journal of neurology 2000;123 ( Pt 10)():2130-40.
2000: Esther A Croes; Bart Dermaut; Tischa J M van der Cammen; Christine Van Broeckhoven; C.M. Duijn
Genetic testing should not be advocated as a diagnostic tool in familial forms of dementia.
American journal of human genetics 2000;67(4):1033-5.
2000: M N Koster; Bart Dermaut; Marc Cruts; Jeanine J Houwing-Duistermaat; Gerwin Roks; Johannes L Tol; Alewijn Ott; Albert Hofman; G Munteanu; Monique Breteler; C.M. Duijn; Christine Van Broeckhoven
The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.
Neurology 2000;55(5):678-84.
2000: Inga Zerr; Jean-Philippe Brandel; C Masullo; DP Wientjens; R De Silva; Martin Zeidler; E Granieri; S Sampaolo; C.M. Duijn; Nicole Delasnerie-Lauprêtre; Robert Will; Sigrid Poser
European surveillance on Creutzfeldt-Jakob disease: a case-control study for medical risk factors.
Journal of clinical epidemiology 2000;53(7):747-54.
2000: André G Uitterlinden; H Burger; C.M. Duijn; Q Huang; Albert Hofman; JC Birkenhäger; Johannes P T M van Leeuwen; Huibert A P Pols
Adjacent genes, for COL2A1 and the vitamin D receptor, are associated with separate features of radiographic osteoarthritis of the knee.
Arthritis and rheumatism 2000;43(7):1456-64.
2000: Biswadjiet S Harhangi; Maarten C de Rijk; C.M. Duijn; Christine Van Broeckhoven; Albert Hofman; Monique Breteler
APOE and the risk of PD with or without dementia in a population-based study.
Neurology 2000;54(6):1272-6.
2000: S Van Gestel; Jeanine J Houwing-Duistermaat; Rolf Adolfsson; C.M. Duijn; Christine Van Broeckhoven
Power of selective genotyping in genetic association analyses of quantitative traits.
Behavior genetics 2000;30(2):141-6.
2000: Jessie Theuns; Jurgen Del-Favero; Bart Dermaut; C.M. Duijn; Hubert Backhovens; Marleen Van den Broeck; Sally Serneels; Ellen Corsmit; Christine Van Broeckhoven; Marc Cruts
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression.
Human molecular genetics 2000;9(3):325-31.
1999: Gerwin Roks; Bart Dermaut; Peter Heutink; Ann Julliams; Hubert Backhovens; M Van de Broeck; Sally Serneels; Albert Hofman; Christine Van Broeckhoven; C.M. Duijn; Marc Cruts
Mutation screening of the tau gene in patients with early-onset Alzheimer's disease.
Neuroscience letters 1999;277(2):137-9.
1999: Kala M Mehta; Alewijn Ott; Sandra Kalmijn; A J C Slooter; C.M. Duijn; Albert Hofman; Monique Breteler
Head trauma and risk of dementia and Alzheimer's disease: The Rotterdam Study.
Neurology 1999;53(9):1959-62.
1999: A J C Slooter; J Bronzova; Jacqueline C M Witteman; Christine Van Broeckhoven; Albert Hofman; C.M. Duijn
Estrogen use and early onset Alzheimer's disease: a population-based study.
Journal of neurology, neurosurgery, and psychiatry 1999;67(6):779-81.
1999: E Bettina Samrén; C.M. Duijn; G C Christiaens; Albert Hofman; Dick Lindhout
Antiepileptic drug regimens and major congenital abnormalities in the offspring.
Annals of neurology 1999;46(5):739-46.
1999: A J C Slooter; Marc Cruts; Alewijn Ott; Michiel Bots; Jacqueline C M Witteman; Albert Hofman; Christine Van Broeckhoven; Monique Breteler; C.M. Duijn
The effect of APOE on dementia is not through atherosclerosis: the Rotterdam Study.
Neurology 1999;53(7):1593-5.
1999: C.M. Duijn; Marc Cruts; Jessie Theuns; G Van Gassen; Hubert Backhovens; Marleen Van den Broeck; A Wehnert; Sally Serneels; Albert Hofman; Christine Van Broeckhoven
Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease in a population-based sample.
European journal of human genetics : EJHG 1999;7(7):801-6.
1999: Biswadjiet S Harhangi; Ben A Oostra; Peter Heutink; C.M. Duijn; Albert Hofman; Monique Breteler
N-acetyltransferase-2 polymorphism in Parkinson's disease: the Rotterdam study.
Journal of neurology, neurosurgery, and psychiatry 1999;67(4):518-20.
1999: Ingrid Meulenbelt; C Bijkerk; S C De Wildt; HS Miedema; FC Breedveld; Huibert A P Pols; Albert Hofman; C.M. Duijn; P Eline Slagboom
Haplotype analysis of three polymorphisms of the COL2A1 gene and associations with generalised radiological osteoarthritis.
Annals of human genetics 1999;63(Pt 5):393-400.
1999: C Bijkerk; Jeanine J Houwing-Duistermaat; HA Valkenburg; Ingrid Meulenbelt; Albert Hofman; F C Breedveld; Huibert A P Pols; C.M. Duijn; P Eline Slagboom
Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine.
Arthritis and rheumatism 1999;42(8):1729-35.
1999: A Alperovitch; Inga Zerr; Maurizio Pocchiari; Eva Mitrova; Jesús de Pedro-Cuesta; I Hegyi; Steven Collins; Hans A Kretzschmar; C.M. Duijn; Robert G Will
Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease.
Lancet 1999;353(9165):1673-4.
1999: A J C Slooter; Jeanine J Houwing-Duistermaat; Frans van Harskamp; Marc Cruts; Christine Van Broeckhoven; Monique Breteler; Albert Hofman; T Stijnen; C.M. Duijn
Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study.
Journal of neurology 1999;246(4):304-8.
1999: C.M. Duijn
Hormone replacement therapy and Alzheimer's disease.
Maturitas 1999;31(3):201-5.
1999: Henry Houlden; Patrizia Rizzu; M Stevens; P de Knijff; C.M. Duijn; John C van Swieten; Peter Heutink; Jordi Perez-Tur; V Thomas; Matt Baker; H Morris; Martin N Rossor; J C Jannsen; Ronald C. Petersen; P Dodd; F Dark; Bradley Boeve; dennis dickson; Peter Davies; Stuart Pickering-Brown; D M A Mann; Jennifer Adamson; Timothy Lynch; Haydeh Payami; John Hardy
Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations.
Neuroscience letters 1999;260(3):193-5.
1999: M van Stuijvenberg; E van Beijeren; N H Wils; Gerarda Derksen-Lubsen; C.M. Duijn; Henriëtte A Moll
Characteristics of the initial seizure in familial febrile seizures.
Archives of disease in childhood 1999;80(2):178-80.
1999: Patrizia Rizzu; John C van Swieten; Marijke Joosse; M Hasegawa; M Stevens; Aad Tibben; Martinus F Niermeijer; M Hillebrand; Rivka Ravid; Ben A Oostra; Michel Goedert; C.M. Duijn; Peter Heutink
High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands.
American journal of human genetics 1999;64(2):414-21.
1999: Johannes L Tol; Gerwin Roks; A J C Slooter; C.M. Duijn
Genetic and environmental factors in Alzheimer's disease.
Revue neurologique 1999;155 Suppl 4():S10-6.
1999: Bart Dermaut; Marc Cruts; A J C Slooter; S Van Gestel; Chris De Jonghe; hugo vanderstichele; Eugeen Vanmechelen; Monique Breteler; Albert Hofman; C.M. Duijn; Christine Van Broeckhoven
The Glu318Gly substitution in presenilin 1 is not causally related to Alzheimer disease.
American journal of human genetics 1999;64(1):290-2.
1998: Gerwin Roks; Marc Cruts; María J Bullido; Hubert Backhovens; María J Artiga; Albert Hofman; Fernando Valdivieso; Christine Van Broeckhoven; C.M. Duijn
The -491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer's disease.
Neuroscience letters 1998;258(2):65-8.
1998: Caroline C W Klaver; Roger Wolfs; Jacqueline J M Assink; C.M. Duijn; Albert Hofman; Paulus T V M de Jong
Genetic risk of age-related maculopathy. Population-based familial aggregation study.
Archives of ophthalmology 1998;116(12):1646-51.
1998: Roger Wolfs; Caroline C W Klaver; RS Ramrattan; C.M. Duijn; Albert Hofman; Paulus T V M de Jong
Genetic risk of primary open-angle glaucoma. Population-based familial aggregation study.
Archives of ophthalmology 1998;116(12):1640-5.
1998: Patrick Cras; F van Harskamp; L Hendriks; Chantal Ceuterick; C.M. Duijn; S Z Stefanko; Albert Hofman; J M Kros; Christine Van Broeckhoven; Jean-Jacques Martin
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.
Acta neuropathologica 1998;96(3):253-60.
1998: Tischa J M van der Cammen; C J Verschoor; C P van Loon; Frans van Harskamp; Inge de Koning; W Joost Schudel; A J C Slooter; Christine Van Broeckhoven; C.M. Duijn
Risk of left ventricular dysfunction in patients with probable Alzheimer's disease with APOE*4 allele.
Journal of the American Geriatrics Society 1998;46(8):962-7.
1998: A J C Slooter; Marc Cruts; Sandra Kalmijn; Albert Hofman; Monique Breteler; Christine Van Broeckhoven; C.M. Duijn
Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study.
Archives of neurology 1998;55(7):964-8.
1998: Caroline C W Klaver; Mike Kliffen; C.M. Duijn; Albert Hofman; Marc Cruts; Diederick Grobbee; Christine Van Broeckhoven; Paulus T V M de Jong
Genetic association of apolipoprotein E with age-related macular degeneration.
American journal of human genetics 1998;63(1):200-6.
1998: Alewijn Ott; A J C Slooter; Albert Hofman; Frans van Harskamp; Jacqueline C M Witteman; Christine Van Broeckhoven; C.M. Duijn; Monique Breteler
Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study.
Lancet 1998;351(9119):1840-3.
1998: Ingrid Meulenbelt; C Bijkerk; HS Miedema; FC Breedveld; Albert Hofman; HA Valkenburg; Huibert A P Pols; P Eline Slagboom; C.M. Duijn
A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam Study).
Annals of the rheumatic diseases 1998;57(6):371-4.
1998: M Stevens; C.M. Duijn; W Kamphorst; P de Knijff; Peter Heutink; W A van Gool; Philip scheltens; Rivka Ravid; B A Oostra; M F Niermeijer; John C van Swieten
Familial aggregation in frontotemporal dementia.
Neurology 1998;50(6):1541-5.
1998: Robert G Will; A Alperovitch; Sigrid Poser; Maurizio Pocchiari; Albert Hofman; Eva Mitrova; R De Silva; M D'Alessandro; Nicole Delasnerie-Laupretre; Inga Zerr; C.M. Duijn
Descriptive epidemiology of Creutzfeldt-Jakob disease in six European countries, 1993-1995. EU Collaborative Study Group for CJD.
Annals of neurology 1998;43(6):763-7.
1998: A J C Slooter; P de Knijff; Albert Hofman; Marc Cruts; Monique Breteler; Christine Van Broeckhoven; L M Havekes; C.M. Duijn
Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study.
Neuroscience letters 1998;248(1):21-4.
1998: Peter de Knijff; C.M. Duijn
Role of APOE in dementia: A critical reappraisal.
Haemostasis 1998;28(3-4):195-201.
1998: C.M. Duijn; Nicole Delasnerie-Lauprêtre; C Masullo; Inga Zerr; R De Silva; DP Wientjens; Jean-Philippe Brandel; T Weber; V Bonavita; Martin Zeidler; Annick Alpérovitch; Sigrid Poser; E Granieri; Albert Hofman; Robert G Will
Case-control study of risk factors of Creutzfeldt-Jakob disease in Europe during 1993-95. European Union (EU) Collaborative Study Group of Creutzfeldt-Jakob disease (CJD).
Lancet 1998;351(9109):1081-5.
1998: S Fahim; C.M. Duijn; FM Baker; Lenore J Launer; Monique Breteler; W Joost Schudel; Albert Hofman
A study of familial aggregation of depression, dementia and Parkinson's disease.
European journal of epidemiology 1998;14(3):233-8.
1998: A van Esch; Ewout W Steyerberg; C.M. Duijn; M Offringa; Gerarda Derksen-Lubsen; H A van Steensel-Moll
Prediction of febrile seizures in siblings: a practical approach.
European journal of pediatrics 1998;157(4):340-4.
1998: A J C Slooter; C.M. Duijn; Michiel Bots; A Ott; Monique Breteler; J De Voecht; A Wehnert; P de Knijff; L M Havekes; Diederick Grobbee; Christine Van Broeckhoven; Albert Hofman
Apolipoprotein E genotype, atherosclerosis, and cognitive decline: the Rotterdam Study.
Journal of neural transmission. Supplementum 1998;53():17-29.
1998: Marc Cruts; C.M. Duijn; Hubert Backhovens; Marleen Van den Broeck; A Wehnert; Sally Serneels; R Sherrington; Michael Hutton; John Hardy; Peter St George-Hyslop; Albert Hofman; Christine Van Broeckhoven
Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease.
Human molecular genetics 1998;7(1):43-51.
1997: Lindsay A Farrer; L Adrienne Cupples; Jonathan L Haines; Bradley T Hyman; Walter A Kukull; Richard Mayeux; Richard H Myers; Margaret Pericak-Vance; N Risch; C.M. Duijn
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
JAMA : the journal of the American Medical Association 1997;278(16):1349-56.
1997: Ingrid Meulenbelt; C Bijkerk; S C de Wildt; H S Miedema; HA Valkenburg; F C Breedveld; Huibert A P Pols; Johan teKoppele; V F Sloos; Albert Hofman; P Eline Slagboom; C.M. Duijn
Investigation of the association of the CRTM and CRTL1 genes with radiographically evident osteoarthritis in subjects from the Rotterdam study.
Arthritis and rheumatism 1997;40(10):1760-5.
1997: E Bettina Samrén; C.M. Duijn; S Koch; Vilho Hiilesmaa; H Klepel; A H Bardy; G B Mannagetta; A W Deichl; Eija Gaily; Marja-Liisa Granström; H Meinardi; Diederick Grobbee; Albert Hofman; Dieter Janz; Dick Lindhout
Maternal use of antiepileptic drugs and the risk of major congenital malformations: a joint European prospective study of human teratogenesis associated with maternal epilepsy.
Epilepsia 1997;38(9):981-90.
1997: André G Uitterlinden; H Burger; Q Huang; E Odding; C.M. Duijn; Albert Hofman; JC Birkenhäger; Johannes P T M van Leeuwen; Huibert A P Pols
Vitamin D receptor genotype is associated with radiographic osteoarthritis at the knee.
The Journal of clinical investigation 1997;100(2):259-63.
1997: C.M. Duijn
Menopause and the brain.
Journal of psychosomatic obstetrics and gynaecology 1997;18(2):121-5.
1997: M Stevens; C.M. Duijn; P de Knijff; Christine Van Broeckhoven; Peter Heutink; B A Oostra; M F Niermeijer; John C van Swieten
Apolipoprotein E gene and sporadic frontal lobe dementia.
Neurology 1997;48(6):1526-9.
1997: Greer M Murphy; Edith Sullivan; Dolores Gallagher-Thompson; Larry Wolford Thompson; C.M. Duijn; Lysia S Forno; William G Ellis; William J Jagust; Jerome A Yesavage; Jared R Tinklenberg
No association between the alpha 1-antichymotrypsin A allele and Alzheimer's disease.
Neurology 1997;48(5):1313-6.
1997: A J C Slooter; Ming-Xin Tang; C.M. Duijn; Yaakov Stern; A Ott; Karen Bell; Monique Breteler; Christine Van Broeckhoven; TK Tatemichi; Benjamin Tycko; Albert Hofman; Richard Mayeux
Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.
JAMA : the journal of the American Medical Association 1997;277(10):818-21.
1997: Peter Heutink; M Stevens; Patrizia Rizzu; E Bakker; Johan M Kros; Aad Tibben; Martinus F Niermeijer; C.M. Duijn; Ben A Oostra; John C van Swieten
Hereditary frontotemporal dementia is linked to chromosome 17q21-q22: a genetic and clinicopathological study of three Dutch families.
Annals of neurology 1997;41(2):150-9.
1997: Albert Hofman; Alewijn Ott; Monique Breteler; Michiel Bots; A J C Slooter; Frans van Harskamp; C.M. Duijn; Christine Van Broeckhoven; Diederick Grobbee
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study.
Lancet 1997;349(9046):151-4.
1997: A J C Slooter; C.M. Duijn
Genetic epidemiology of Alzheimer disease.
Epidemiologic reviews 1997;19(1):107-19.
1997: Aad Tibben; M Stevens; G M de Wert; Martinus F Niermeijer; C.M. Duijn; J C van Swieten
Preparing for presymptomatic DNA testing for early onset Alzheimer's disease/cerebral haemorrhage and hereditary Pick disease.
Journal of medical genetics 1997;34(1):63-72.
1996: A J C Slooter; Willem A van Gool; C.M. Duijn
[The role of apolipoproteins E genotyping in the differential diagnosis of dementia].
Nederlands tijdschrift voor geneeskunde 1996;140(42):2073-6.
1996: André G Uitterlinden; Huibert A P Pols; H Burger; Q Huang; P L A van Daele; C.M. Duijn; Albert Hofman; JC Birkenhäger; Johannes P T M van Leeuwen
A large-scale population-based study of the association of vitamin D receptor gene polymorphisms with bone mineral density.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1996;11(9):1241-8.
1996: V S Rao; A Cupples; C.M. Duijn; Alexander Kurz; R C Green; H Chui; Ranjan Duara; S A Auerbach; Ladislav Volicer; J Wells; Christine Van Broeckhoven; John H Growdon; Jonathan L Haines; Lindsay A Farrer
Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4.
American journal of human genetics 1996;59(3):664-75.
1996: A J C Slooter; Monique Breteler; Alewijn Ott; Christine Van Broeckhoven; C.M. Duijn
APOE genotyping in differential diagnosis of Alzheimer's disease.
Lancet 1996;348(9023):334.
1996: J Bronzova; C.M. Duijn; L M Havekes; P de Knijff; Christine Van Broeckhoven; Albert Hofman
Apolipoprotein E genotype and concomitant clinical features in early-onset Alzheimer's disease.
Journal of neurology 1996;243(6):465-8.
1996: C.M. Duijn
Epidemiology of the dementias: recent developments and new approaches.
Journal of neurology, neurosurgery, and psychiatry 1996;60(5):478-88.
1996: D P Wientjens; Z Davanipour; Albert Hofman; K Kondo; W B Matthews; Robert G Will; C.M. Duijn
Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies.
Neurology 1996;46(5):1287-91.
1996: W N Samson; C.M. Duijn; W C Hop; Albert Hofman
Clinical features and mortality in patients with early-onset Alzheimer's disease.
European neurology 1996;36(2):103-6.
1995: Lindsay A Farrer; L A Cupples; C.M. Duijn; Alexander Kurz; R Zimmer; U Müller; R C Green; V Clarke; J Shoffner; D C Wallace
Apolipoprotein E genotype in patients with Alzheimer's disease: implications for the risk of dementia among relatives.
Annals of neurology 1995;38(5):797-808.
1995: Marc Cruts; Hubert Backhovens; Geert Van Gassen; Jessie Theuns; S Y Wang; A Wehnert; C.M. Duijn; T Karlsson; Albert Hofman; R Adolfsson
Mutation analysis of the chromosome 14q24.3 dihydrolipoyl succinyltransferase (DLST) gene in patients with early-onset Alzheimer disease.
Neuroscience letters 1995;199(1):73-7.
1995: Lindsay A Farrer; L Adrienne Cupples; C.M. Duijn; L Connor-Lacke; D K Kiely; John H Growdon
Rate of progression of Alzheimer's disease is associated with genetic risk.
Archives of neurology 1995;52(9):918-23.
1995: Willem A van Gool; H M Evenhuis; C.M. Duijn
A case-control study of apolipoprotein E genotypes in Alzheimer's disease associated with Down's syndrome. Dutch Study Group on Down's Syndrome and Ageing.
Annals of neurology 1995;38(2):225-30.
1995: Daniel Commenges; H Jacqmin; Luc Letenneur; C.M. Duijn
Score test for familial aggregation in probands studies: application to Alzheimer's disease.
Biometrics 1995;51(2):542-51.
1995: C.M. Duijn; P de Knijff; A Wehnert; J De Voecht; J B Bronzova; L M Havekes; Albert Hofman; Christine Van Broeckhoven
The apolipoprotein E epsilon 2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival.
Annals of neurology 1995;37(5):605-10.
1995: M Stevens; John C van Swieten; C.M. Duijn; Aad Tibben; M F Niermeijer
[Familial forms of fronto-temporal dementia].
Nederlands tijdschrift voor geneeskunde 1995;139(17):871-5.
1995: C.M. Duijn; L M Havekes; Christine Van Broeckhoven; P de Knijff; Albert Hofman
Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.
BMJ (Clinical research ed.) 1995;310(6980):627-31.
1994: V S Rao; C.M. Duijn; L Connor-Lacke; L Adrienne Cupples; John H Growdon; Lindsay A Farrer
Multiple etiologies for Alzheimer disease are revealed by segregation analysis.
American journal of human genetics 1994;55(5):991-1000.
1994: C.M. Duijn; L Hendriks; Lindsay A Farrer; Hubert Backhovens; Marc Cruts; A Wehnert; Albert Hofman; Christine Van Broeckhoven
A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21.
American journal of human genetics 1994;55(4):714-27.
1994: E Nijhuis; B Hinloopen; C.M. Duijn; Albert Hofman; Jan Rozing; Lex Nagelkerken
Decreased sensitivity to dexamethasone in lymphocytes from patients with Alzheimer's disease.
Clinical immunology and immunopathology 1994;73(1):45-52.
1994: K M Berberian; C.M. Duijn; Arno Hoes; H A Valkenburg; Albert Hofman
Alcohol and mortality. Results from the EPOZ (Epidemiologic Study of Cardiovascular Risk Indicators) follow-up study.
European journal of epidemiology 1994;10(5):587-93.
1994: Joost Haan; Christine Van Broeckhoven; C.M. Duijn; E Voorhoeve; Frans van Harskamp; John C van Swieten; Marion L C Maat-Schieman; Raymund A C Roos; Egbert Bakker
The apolipoprotein E epsilon 4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations.
Annals of neurology 1994;36(3):434-7.
1994: C.M. Duijn; H A van Steensel-Moll; J W Coebergh; G E van Zanen
Risk factors for childhood acute non-lymphocytic leukemia: an association with maternal alcohol consumption during pregnancy?
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1994;3(6):457-60.
1994: C.M. Duijn; P de Knijff; Marc Cruts; A Wehnert; L M Havekes; Albert Hofman; Christine Van Broeckhoven
Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease.
Nature genetics 1994;7(1):74-8.
1994: C.M. Duijn; D G Clayton; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; J A Mortimer
Interaction between genetic and environmental risk factors for Alzheimer's disease: a reanalysis of case-control studies. EURODEM Risk Factors Research Group.
Genetic epidemiology 1994;11(6):539-51.
1993: C.M. Duijn; Lindsay A Farrer; L Adrienne Cupples; Albert Hofman
Genetic transmission of Alzheimer's disease among families in a Dutch population based study.
Journal of medical genetics 1993;30(8):640-6.
1992: H A van Steensel-Moll; C.M. Duijn; H A Valkenburg; G E van Zanen
Predominance of hospital deliveries among children with acute lymphocytic leukemia: speculations about neonatal exposure to fluorescent light.
Cancer causes & control : CCC 1992;3(4):389-90.
1992: D Clayton; C.M. Duijn
Re: "Case-control studies of environmental influences in diseases with genetic determinants, with an application to Alzheimer's disease".
American journal of epidemiology 1992;135(11):1315-8.
1992: L Hendriks; C.M. Duijn; Patrick Cras; Marc Cruts; Wim Van Hul; Frans van Harskamp; AC Warren; Melvin G McInnis; S E Antonarakis; Jean-Jacques Martin
Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.
Nature genetics 1992;1(3):218-21.
1992: Flora E van Leeuwen; C.M. Duijn; M H Camps; B A Kempers; M F Mentjens; H B Mulder; E G Schouten; R M Zwijsen; M A Rookus
Agreement between oral contraceptive users and prescribers: implications for case-control studies.
Contraception 1992;45(5):399-408.
1992: C.M. Duijn; T A Tanja; R Haaxma; W Schulte; R J Saan; A J Lameris; G Antonides-Hendriks; Albert Hofman
Head trauma and the risk of Alzheimer's disease.
American journal of epidemiology 1992;135(7):775-82.
1992: C.M. Duijn; Albert Hofman
Risk factors for Alzheimer's disease: the EURODEM collaborative re-analysis of case-control studies.
Neuroepidemiology 1992;11 Suppl 1():106-13.
1992: Monique Breteler; J J Claus; C.M. Duijn; L J Launer; Albert Hofman
Epidemiology of Alzheimer's disease.
Epidemiologic reviews 1992;14():59-82.
1991: M E Boerrigter; C.M. Duijn; E Mullaart; Piet Eikelenboom; C M van der Togt; D L Knook; Albert Hofman; Jan Vijg
Decreased DNA repair capacity in familial, but not in sporadic Alzheimer's disease.
Neurobiology of aging 1991;12(4):367-70.
1991: C.M. Duijn; Albert Hofman
Relation between nicotine intake and Alzheimer's disease.
BMJ (Clinical research ed.) 1991;302(6791):1491-4.
1991: C.M. Duijn; L Hendriks; Marc Cruts; John Hardy; Albert Hofman; Christine Van Broeckhoven
Amyloid precursor protein gene mutation in early-onset Alzheimer's disease.
Lancet 1991;337(8747):978.
1991: C.M. Duijn; Christine Van Broeckhoven; John Hardy; Alison Goate; Martin N Rossor; A Vandenberghe; J J Martin; Albert Hofman; Michael Mullan
Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1991;158():471-4.
1991: Anthony Jorm; C.M. Duijn; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Emre Kokmen; K Kondo; J A Mortimer; W A Rocca
Psychiatric history and related exposures as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S43-7.
1991: Amy Borenstein Graves; C.M. Duijn; V Chandra; Laura Fratiglioni; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; J A Mortimer; W A Rocca
Occupational exposures to solvents and lead as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S58-61.
1991: Amy Borenstein Graves; C.M. Duijn; V Chandra; Laura Fratiglioni; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; J A Mortimer; W A Rocca
Alcohol and tobacco consumption as risk factors for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S48-57.
1991: C.M. Duijn; T Stijnen; Albert Hofman
Risk factors for Alzheimer's disease: overview of the EURODEM collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S4-12.
1991: Monique Breteler; C.M. Duijn; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; J A Mortimer
Medical history and the risk of Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S36-42.
1991: J A Mortimer; C.M. Duijn; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; W A Rocca
Head trauma as a risk factor for Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S28-35.
1991: W A Rocca; C.M. Duijn; D Clayton; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo
Maternal age and Alzheimer's disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group.
International journal of epidemiology 1991;20 Suppl 2():S21-7.
1991: C.M. Duijn; D Clayton; V Chandra; Laura Fratiglioni; Amy Borenstein Graves; A Heyman; Anthony Jorm; Emre Kokmen; K Kondo; J A Mortimer; W A Rocca; S L Shalat; Hilkka Soininen; Albert Hofman
Familial aggregation of Alzheimer's disease and related disorders: a collaborative re-analysis of case-control studies.
International journal of epidemiology 1991;20 Suppl 2():S13-20.
1990: Albert Hofman; C.M. Duijn; W Schulte; T A Tanja; R Haaxma; A J Lameris; R J Saan
Is parental age related to the risk of Alzheimer's disease?
The British journal of psychiatry : the journal of mental science 1990;157():273-5.
1990: C.M. Duijn; Albert Hofman; L Nagelkerken
Serum levels of interleukin-6 are not elevated in patients with Alzheimer's disease.
Neuroscience letters 1990;108(3):350-4.
1989: Albert Hofman; W Schulte; T A Tanja; C.M. Duijn; R Haaxma; A J Lameris; V M Otten; R J Saan
History of dementia and Parkinson's disease in 1st-degree relatives of patients with Alzheimer's disease.
Neurology 1989;39(12):1589-92.
1988: C.M. Duijn; H A van Steensel-Moll; A van der Does-vd Berg; Elisabeth R van Wering; G E van Zanen; H A Valkenburg; J A Rammeloo
Infant feeding and childhood cancer.
Lancet 1988;2(8614):796-7.
1988: F J Kok; C.M. Duijn; Albert Hofman; G B Van der Voet; F A De Wolff; C H Paays; H A Valkenburg
Serum copper and zinc and the risk of death from cancer and cardiovascular disease.
American journal of epidemiology 1988;128(2):352-9.
1988: Albert Hofman; C.M. Duijn; W A Rocca
Is Alzheimer's disease distinct from normal ageing?
Lancet 1988;2(8604):226-7.
1987: F J Kok; C.M. Duijn; Albert Hofman; R Vermeeren; A M de Bruijn; H A Valkenburg
Micronutrients and the risk of lung cancer.
The New England journal of medicine 1987;316(22):1416.