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Cheng-Xin Gong

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Yanxing Chen; Chun-Ling Dai; Julie Blanchard; Inge Grundke-Iqbal; Khalid Iqbal; Moon H Lee; Zhihou Liang; Fei Liu; Shenggang Sun; Cheng-Xin Gong
A non-transgenic mouse model (icv-STZ mouse) of Alzheimer's disease: similarities to and differences from the transgenic model (3xTg-AD mouse).
Nana Jin; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Wei Qian; Xiaomin Yin; Lan Zhang; Fei Liu
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease.
Yan Yang; Xuefeng Yu; Muxun Zhang; Shuhong Hu; Teng Jiang; Delin Ma; Yuping Wang; Cheng-Xin Gong
Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes.

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2013: Yanxing Chen; Chun-Ling Dai; Julie Blanchard; Inge Grundke-Iqbal; Khalid Iqbal; Moon H Lee; Zhihou Liang; Fei Liu; Shenggang Sun; Cheng-Xin Gong
A non-transgenic mouse model (icv-STZ mouse) of Alzheimer's disease: similarities to and differences from the transgenic model (3xTg-AD mouse).
Molecular neurobiology 2013;47(2):711-25.
2013: Nana Jin; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Wei Qian; Xiaomin Yin; Lan Zhang; Fei Liu
CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease.
Nucleic acids research 2013;41(5):3240-56.
2013: Yan Yang; Xuefeng Yu; Muxun Zhang; Shuhong Hu; Teng Jiang; Delin Ma; Yuping Wang; Cheng-Xin Gong
Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes.
Journal of Alzheimer's disease : JAD 2013;33(2):329-38.
2012: Jianhua Shi; Shiliang Wu; Chun-ling Dai; Inge Grundke-Iqbal; Khalid Iqbal; Yi Li; Fei Liu; Cheng-Xin Gong
Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells.
FEBS letters 2012;586(16):2443-50.
2012: Jianlan Gu; Inge-Grundke Iqbal; Khalid Iqbal; Nana Jin; Wei Qian; Jianhua Shi; Shiliang Wu; Jianhua Zhou; Cheng-Xin Gong; Fei Liu
Cyclic AMP-dependent protein kinase regulates 9G8-mediated alternative splicing of tau exon 10.
FEBS letters 2012;586(16):2239-44.
2012: Shaohong Ding; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Wei Qian; Jianhua Shi; Fei Liu
Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A.
Neurobiology of aging 2012;33(7):1389-99.
2012: Yanxing Chen; Chun-Ling Dai; Inge Grundke-Iqbal; Khalid Iqbal; Frank M LaFerla; Moon H Lee; Zhihou Liang; Fei Liu; Shenggang Sun; Zhu Tian; Cheng-Xin Gong
Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease.
PloS one 2012;7(12):e51432.
2012: Ying Liu; Xiaoqin Run; Jianhua Shi; Yang Yu; Inge Grundke-Iqbal; Khalid Iqbal; Xiaojing Li; Yi Li; Zhihou Liang; Fei Liu; Chun-ling Dai; Cheng-Xin Gong
Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain.
PloS one 2012;7(8):e43724.
2012: Yang Yu; Lan Zhang; Inge Grundke-Iqbal; Khalid Iqbal; Moon H Lee; Xiaojing Li; Yi Li; Zhihou Liang; Fei Liu; Ying Liu; Xiaoqin Run; David J Vocadlo; Cheng-Xin Gong
Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation.
PloS one 2012;7(4):e35277.
2011: Ying Liu; Inge Grundke-Iqbal; Khalid Iqbal; Fei Liu; Cheng-Xin Gong
Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes.
The Journal of pathology 2011;225(1):54-62.
2011: Wei Qian; Jianhua Shi; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Nana Jin; Hongwei Liang; Fei Liu
Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A.
Nucleic acids research 2011;39(14):6161-71.
2011: Wei Qian; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong; Fei Liu
Splicing factor SC35 promotes tau expression through stabilization of its mRNA.
FEBS letters 2011;585(6):875-80.
2011: Jerzy Wegiel; Wojciech Kaczmarski; Madhabi Barua; Izabela Kuchna; Krzysztof Nowicki; Kuo-Chiang Wang; Jarek Wegiel; Shuang Ma Yang; Janusz Frackowiak; Bozena Mazur-Kolecka; WAYNE SILVERMAN; Barry Reisberg; Isabel Monteiro; Mony J de Leon; Thomas Wisniewski; Arthur Dalton; Florence Lai; Yu-Wen Hwang; Tatyana Adayev; Fei Liu; Khalid Iqbal; Inge-Grundke Iqbal; Cheng-Xin Gong
Link between DYRK1A overexpression and several-fold enhancement of neurofibrillary degeneration with 3-repeat tau protein in Down syndrome.
Journal of neuropathology and experimental neurology 2011;70(1):36-50.
2011: Wei Qian; Xiaomin Yin; Wen Hu; Jianhua Shi; Jianlan Gu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong; Fei Liu
Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;23(4):617-27.
2011: Jerzy Wegiel; Cheng-Xin Gong; Yu-Wen Hwang
The role of DYRK1A in neurodegenerative diseases.
The FEBS journal 2011;278(2):236-45.
2010: Khalid Iqbal; Fei Liu; Cheng-Xin Gong; Inge Grundke-Iqbal
Tau in Alzheimer disease and related tauopathies.
Current Alzheimer research 2010;7(8):656-64.
2010: Khalid Iqbal; Xiaochuan Wang; Julie Blanchard; Fei Liu; Cheng-Xin Gong; Inge Grundke-Iqbal
Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial.
Biochemical Society transactions 2010;38(4):962-6.
2010: Z Yao; Z Guo; C Yang; Qing Tian; Cheng-Xin Gong; G Liu; Jian-Zhi Wang
Phenylbutyric acid prevents rats from electroconvulsion-induced memory deficit with alterations of memory-related proteins and tau hyperphosphorylation.
Neuroscience 2010;168(2):405-15.
2010: Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal
Targeting tau protein in Alzheimer's disease.
Drugs & aging 2010;27(5):351-65.
2010: Xiaoqin Run; Zhihou Liang; Cheng-Xin Gong
Anesthetics and tau protein: animal model studies.
Journal of Alzheimer's disease : JAD 2010;22 Suppl 3():49-55.
2010: Wei Qian; Jianhua Shi; Xiaomin Yin; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong; Fei Liu
PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta.
Journal of Alzheimer's disease : JAD 2010;19(4):1221-9.
2009: Yanqiu Deng; Bin Li; Ying Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease.
The American journal of pathology 2009;175(5):2089-98.
2009: Ying Liu; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease.
Journal of neurochemistry 2009;111(1):242-9.
2009: Fei Liu; Jianhua Shi; Hitoshi Tanimukai; Jinhua Gu; Jianlan Gu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease.
Brain : a journal of neurology 2009;132(Pt 7):1820-32.
2009: Khalid Iqbal; Fei Liu; Cheng-Xin Gong; Alejandra del C Alonso; Inge Grundke-Iqbal
Mechanisms of tau-induced neurodegeneration.
Acta neuropathologica 2009;118(1):53-69.
2009: Yang Yu; Xiaoqin Run; Zhihou Liang; Yi Li; Fei Liu; Ying Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases.
Journal of neurochemistry 2009;108(6):1480-94.
2009: Zhihou Liang; Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage.
Journal of Alzheimer's disease : JAD 2009;17(3):531-9.
2009: Xiaoqin Run; Zhihou Liang; Lan Zhang; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Anesthesia induces phosphorylation of tau.
Journal of Alzheimer's disease : JAD 2009;16(3):619-26.
2008: Jianhua Shi; Tianyi Zhang; Chunlei Zhou; Muhammad Omar Chohan; Xiaosong Gu; Jerzy Wegiel; Jianhua Zhou; Yu-Wen Hwang; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong; Fei Liu
Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome.
The Journal of biological chemistry 2008;283(42):28660-9.
2008: Jerzy Wegiel; Karol Dowjat; Wojciech Kaczmarski; Izabela Kuchna; Krzysztof Nowicki; Janusz Frackowiak; Bozena Mazur-Kolecka; Jarek Wegiel; WAYNE SILVERMAN; Barry Reisberg; Mony Deleon; Thomas Wisniewski; Cheng-Xin Gong; Fei Liu; Tatyana Adayev; Mo-Chou Chen-Hwang; Yu-Wen Hwang
The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome.
Acta neuropathologica 2008;116(4):391-407.
2008: Fei Liu; Zhihou Liang; Jerzy Wegiel; Yu-Wen Hwang; Khalid Iqbal; Inge Grundke-Iqbal; Narayan Ramakrishna; Cheng-Xin Gong
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(9):3224-33.
2008: Zhihou Liang; Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Jerzy Wegiel; Cheng-Xin Gong
Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome.
Journal of Alzheimer's disease : JAD 2008;13(3):295-302.
2008: Ying Liu; Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease.
FEBS letters 2008;582(2):359-64.
2008: Cheng-Xin Gong; Khalid Iqbal
Hyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer disease.
Current medicinal chemistry 2008;15(23):2321-8.
2008: Fei Liu; Cheng-Xin Gong
Tau exon 10 alternative splicing and tauopathies.
Molecular neurodegeneration 2008;3():8.
2008: Yanqiu Deng; Bin Li; Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Roland Brandt; Cheng-Xin Gong
Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):138-45.
2007: Fei Liu; Bin Li; E-Jan Tung; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation.
The European journal of neuroscience 2007;26(12):3429-36.
2007: Zhihou Liang; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain.
Journal of neurochemistry 2007;103(6):2462-70.
2006: Fei Liu; Zhihou Liang; Jianhua Shi; Dongmei Yin; Ezzat El-Akkad; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners.
FEBS letters 2006;580(26):6269-74.
2006: Fei Liu; Z Liang; Cheng-Xin Gong
Hyperphosphorylation of tau and protein phosphatases in Alzheimer disease.
Panminerva medica 2006;48(2):97-108.
2006: Xu Li; Fen Lu; Jian-Zhi Wang; Cheng-Xin Gong
Concurrent alterations of O-GlcNAcylation and phosphorylation of tau in mouse brains during fasting.
The European journal of neuroscience 2006;23(8):2078-86.
2006: Cheng-Xin Gong; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal
Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation.
Journal of Alzheimer's disease : JAD 2006;9(1):1-12.
2006: Cheng-Xin Gong; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal
Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target.
Journal of biomedicine & biotechnology 2006;2006(3):31825.
2005: Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal; Yoshiya Oda; Kazuhito Tomizawa; Cheng-Xin Gong
Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain.
The Journal of biological chemistry 2005;280(45):37755-62.
2005: Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation.
The European journal of neuroscience 2005;22(8):1942-50.
2005: Cheng-Xin Gong; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal
Post-translational modifications of tau protein in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(6):813-38.
2005: Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Sandra Rossie; Cheng-Xin Gong
Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease.
The Journal of biological chemistry 2005;280(3):1790-6.
2005: Yu Huang; Fei Liu; Inge Grundke-Iqbal; Khalid Iqbal; Cheng-Xin Gong
NF-kappaB precursor, p105, and NF-kappaB inhibitor, IkappaBgamma, are both elevated in Alzheimer disease brain.
Neuroscience letters 2005;373(2):115-8.
2005: Li Sun; XiaoChuang Wang; Shengyuan Liu; Quan Wang; JianZhi Wang; Malika Bennecib; Cheng-Xin Gong; Amitabha Sengupta; Inge Grundke-Iqbal; Khalid Iqbal
Bilateral injection of isoproterenol into hippocampus induces Alzheimer-like hyperphosphorylation of tau and spatial memory deficit in rat.
FEBS letters 2005;579(1):251-8.
2005: Khalid Iqbal; Alejandra del C Alonso; She Chen; Muhammad Omar Chohan; Ezzat El-Akkad; Cheng-Xin Gong; Sabiha Khatoon; Bin Li; Fei Liu; Abdur Rahman; Hitoshi Tanimukai; Inge Grundke-Iqbal
Tau pathology in Alzheimer disease and other tauopathies.
Biochimica et biophysica acta 2005;1739(2-3):198-210.
2004: Yu Huang; Hitoshi Tanimukai; Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain.
The European journal of neuroscience 2004;20(12):3489-97.
2004: Shi Jie Liu; Jia Yu Zhang; Hong Lian Li; Zheng-Yu Fang; Qun Wang; Heng Mei Deng; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Jian-Zhi Wang
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain.
The Journal of biological chemistry 2004;279(48):50078-88.
2004: Niloufar Haque; Cheng-Xin Gong; Amitabha Sengupta; Khalid Iqbal; Inge Grundke-Iqbal
Regulation of microtubule-associated proteins, protein kinases and protein phosphatases during differentiation of SY5Y cells.
Brain research. Molecular brain research 2004;129(1-2):163-70.
2004: Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Gerald W Hart; Cheng-Xin Gong
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10804-9.
2004: Qing Tian; Z-Q Lin; X-C Wang; J Chen; Q Wang; Cheng-Xin Gong; J-Z Wang
Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit.
Neuroscience 2004;126(2):277-84.
2004: Cheng-Xin Gong; Fei Liu; Guoxin Wu; Sandra Rossie; Jerzy Wegiel; Liang Li; Inge Grundke-Iqbal; Khalid Iqbal
Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5.
Journal of neurochemistry 2004;88(2):298-310.
2003: Jin-Jing Pei; Cheng-Xin Gong; Wen-Lin An; Bengt Winblad; Richard Frank Cowburn; Inge Grundke-Iqbal; Khalid Iqbal
Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease.
The American journal of pathology 2003;163(3):845-58.
2003: Cheng-Xin Gong; Jian-Zhi Wang; Khalid Iqbal; Inge Grundke-Iqbal
Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices.
Neuroscience letters 2003;340(2):107-10.
2003: Khalid Iqbal; Alejandra del C Alonso; Ezzat El-Akkad; Cheng-Xin Gong; Niloufar Haque; Sabiha Khatoon; Jin-Jing Pei; Hitoshi Tanimukai; Ichiro Tsujio; Jian-Zhi Wang; Inge Grundke-Iqba
Alzheimer neurofibrillary degeneration: therapeutic targets and high-throughput assays.
Journal of molecular neuroscience : MN 2003;20(3):425-9.
2002: Fei Liu; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta.
FEBS letters 2002;530(1-3):209-14.
2002: Jin-Jing Pei; Heiko Braak; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal; Bengt Winblad; Richard Frank Cowburn
Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration.
Acta neuropathologica 2002;104(4):369-76.
2002: Khalid Iqbal; Alejandra del C Alonso; Ezzat El-Akkad; Cheng-Xin Gong; Niloufar Haque; Sabiha Khatoon; Jin-Jing Pei; Ichiro Tsujio; Jian-Zhi Wang; Inge Grundke-Iqbal
Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion.
Journal of molecular neuroscience : MN 2002;19(1-2):95-9.
2002: Fei Liu; Tanweer Zaidi; Khalid Iqbal; Inge Grundke-Iqbal; Roberta K Merkle; Cheng-Xin Gong
Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease.
FEBS letters 2002;512(1-3):101-6.
2002: Khalid Iqbal; A del C Alonso; Ezzat El-Akkad; Cheng-Xin Gong; Niloufar Haque; Sabiha Khatoon; Ichiro Tsujio; Inge Grundke-Iqbal
Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration.
Journal of neural transmission. Supplementum 2002;(62):309-19.
2002: Fei Liu; Tanweer Zaidi; Khalid Iqbal; Inge Grundke-Iqbal; Cheng-Xin Gong
Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5.
Neuroscience 2002;115(3):829-37.
2001: L Y Cheng; J Z Wang; Cheng-Xin Gong; Jin-Jing Pei; Tanweer Zaidi; Inge Grundke-Iqbal; Khalid Iqbal
Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue nonbinding phosphatase activities.
Neurochemical research 2001;26(4):425-38.
2001: Malika Bennecib; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal
Inhibition of PP-2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356.
FEBS letters 2001;490(1-2):15-22.
2001: Cheng-Xin Gong; Theodore I Lidsky; Jerzy Wegiel; Inge Grundke-Iqbal; Khalid Iqbal
Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain.
Brain research. Brain research protocols 2001;6(3):134-40.
2000: Malika Bennecib; Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal
Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain.
FEBS letters 2000;485(1):87-93.
2000: Cheng-Xin Gong; Theodore I Lidsky; Jerzy Wegiel; L Zuck; Inge Grundke-Iqbal; Khalid Iqbal
Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease.
The Journal of biological chemistry 2000;275(8):5535-44.
2000: Cheng-Xin Gong; Jerzy Wegiel; Theodore I Lidsky; L Zuck; Jesús Avila; Henryk M Wisniewski; Inge Grundke-Iqbal; Khalid Iqbal
Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain.
Brain research 2000;853(2):299-309.
2000: Khalid Iqbal; A D Alonso; J A Gondal; Cheng-Xin Gong; Niloufar Haque; Sabiha Khatoon; Amitabha Sengupta; Jian-Zhi Wang; Inge Grundke-Iqbal
Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach.
Journal of neural transmission. Supplementum 2000;59():213-22.
2000: L Y Cheng; J Z Wang; Cheng-Xin Gong; Jin-Jing Pei; Tanweer Zaidi; Inge Grundke-Iqbal; Khalid Iqbal
Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue binding phosphatases.
Neurochemical research 2000;25(1):107-20.
1998: Khalid Iqbal; A C Alonso; Cheng-Xin Gong; Sabiha Khatoon; Jin-Jing Pei; Jian-Zhi Wang; Inge Grundke-Iqbal
Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles.
Journal of neural transmission. Supplementum 1998;53():169-80.
1998: Jin-Jing Pei; Cheng-Xin Gong; Khalid Iqbal; Inge Grundke-Iqbal; Q L Wu; Bengt Winblad; Richard Frank Cowburn
Subcellular distribution of protein phosphatases and abnormally phosphorylated tau in the temporal cortex from Alzheimer's disease and control brains.
Journal of neural transmission (Vienna, Austria : 1996) 1998;105(1):69-83.
1996: Cheng-Xin Gong; S Shaikh; Inge Grundke-Iqbal; Khalid Iqbal
Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated tau by neuroleptics.
Brain research 1996;741(1-2):95-102.
1995: Cheng-Xin Gong; S Shaikh; J Z Wang; T Zaidi; Inge Grundke-Iqbal; Khalid Iqbal
Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.
Journal of neurochemistry 1995;65(2):732-8.
1995: J Z Wang; Cheng-Xin Gong; T Zaidi; Inge Grundke-Iqbal; Khalid Iqbal
Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.
The Journal of biological chemistry 1995;270(9):4854-60.
1994: Khalid Iqbal; A C Alonso; Cheng-Xin Gong; S Khatoon; T J Singh; Inge Grundke-Iqbal
Mechanism of neurofibrillary degeneration in Alzheimer's disease.
Molecular neurobiology 1994;9(1-3):119-23.
1994: Cheng-Xin Gong; Inge Grundke-Iqbal; Khalid Iqbal
Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A.
Neuroscience 1994;61(4):765-72.
1994: Cheng-Xin Gong; Inge Grundke-Iqbal; Z Damuni; Khalid Iqbal
Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease.
FEBS letters 1994;341(1):94-8.
1994: Cheng-Xin Gong; T J Singh; Inge Grundke-Iqbal; Khalid Iqbal
Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase-2B (calcineurin).
Journal of neurochemistry 1994;62(2):803-6.
1993: Cheng-Xin Gong; T J Singh; Inge Grundke-Iqbal; Khalid Iqbal
Phosphoprotein phosphatase activities in Alzheimer disease brain.
Journal of neurochemistry 1993;61(3):921-7.
1993: Khalid Iqbal; A Alonso; Cheng-Xin Gong; S Khatoon; T Kudo; T Singh; Inge Grundke-Iqbal
Molecular pathology of Alzheimer neurofibrillary degeneration.
Acta neurobiologiae experimentalis 1993;53(1):325-35.