FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jeffrey Kuret

Research Profile

Chemicals & Drugs

Disorders

Phenomena

Genes & Molecular Sequences

Concepts & Ideas

Living Beings

Saccharomyces cerevisiae

Anatomy

Procedures

Microscopy, Electron

Physiology

Mutation

Co-author Network

Publications

TOP 3
Katryna Cisek; Grace L Cooper; Nicolette S Honson; Jordan R Jensen; Kelsey N Schafer; Jeffrey Kuret
Ligand electronic properties modulate tau filament binding site density.
Kelsey N Schafer; Anastasios Matzavinos; Sohee Kim; Jeffrey Kuret
Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: a simulation study.
Katryna Cisek; Jeffrey Kuret
QSAR studies for prediction of cross-β sheet aggregate binding affinity and selectivity.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jeffrey Kuret (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Katryna Cisek; Grace L Cooper; Nicolette S Honson; Jordan R Jensen; Kelsey N Schafer; Jeffrey Kuret
Ligand electronic properties modulate tau filament binding site density.
Biophysical chemistry 2012;170():25-33.
2012: Kelsey N Schafer; Anastasios Matzavinos; Sohee Kim; Jeffrey Kuret
Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: a simulation study.
NeuroImage 2012;60(3):1724-33.
2012: Katryna Cisek; Jeffrey Kuret
QSAR studies for prediction of cross-β sheet aggregate binding affinity and selectivity.
Bioorganic & medicinal chemistry 2012;20(4):1434-41.
2011: Jordan R Jensen; Katryna Cisek; Nicolette S Honson; Jeffrey Kuret
Ligand polarizability contributes to tau fibril binding affinity.
Bioorganic & medicinal chemistry 2011;19(17):5147-54.
2011: K E Funk; R E Mrak; Jeffrey Kuret
Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late-stage autophagic organelles.
Neuropathology and applied neurobiology 2011;37(3):295-306.
2011: Jordan R Jensen; Katryna Cisek; Kristen E Funk; Swati Naphade; Kelsey N Schafer; Jeffrey Kuret
Research towards tau imaging.
Journal of Alzheimer's disease : JAD 2011;26 Suppl 3():147-57.
2010: Swati B Naphade; Kristina A Kigerl; Lyn B Jakeman; Sandra K Kostyk; Phillip Popovich; Jeffrey Kuret
Progranulin expression is upregulated after spinal contusion in mice.
Acta neuropathologica 2010;119(1):123-33.
2009: Edward Chang; Nicolette S Honson; Bhaswati Bandyopadhyay; Kristen E Funk; Jordan R Jensen; Sohee Kim; Swati Naphade; Jeffrey Kuret
Modulation and detection of tau aggregation with small-molecule ligands.
Current Alzheimer research 2009;6(5):409-14.
2009: Erin E Congdon; Yvette H Figueroa; Lili Wang; Galina Toneva; Edward Chang; Jeffrey Kuret; Christopher Conrad; karen duff
Inhibition of tau polymerization with a cyanine dye in two distinct model systems.
The Journal of biological chemistry 2009;284(31):20830-9.
2009: Edward Chang; Erin E Congdon; Nicolette S Honson; karen duff; Jeffrey Kuret
Structure-activity relationship of cyanine tau aggregation inhibitors.
Journal of medicinal chemistry 2009;52(11):3539-47.
2009: Nicolette S Honson; Jordan R Jensen; Aida Abraha; Garth F Hall; Jeffrey Kuret
Small-molecule mediated neuroprotection in an in situ model of tauopathy.
Neurotoxicity research 2009;15(3):274-83.
2008: Edward Chang; Sohee Kim; Haishan Yin; Haikady N Nagaraja; Jeffrey Kuret
Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps.
Journal of neurochemistry 2008;107(4):1113-23.
2008: Mitul Sarkar; Jeffrey Kuret; Gloria Lee
Two motifs within the tau microtubule-binding domain mediate its association with the hsc70 molecular chaperone.
Journal of neuroscience research 2008;86(12):2763-73.
2008: Nicolette S Honson; Jeffrey Kuret
Tau aggregation and toxicity in tauopathic neurodegenerative diseases.
Journal of Alzheimer's disease : JAD 2008;14(4):417-22.
2008: Erin E Congdon; Sohee Kim; Jonathan Bonchak; Tanakorn Songrug; Anastasios Matzavinos; Jeffrey Kuret
Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants.
The Journal of biological chemistry 2008;283(20):13806-16.
2008: John Q Trojanowski; karen duff; Howard Fillit; Walter J Koroshetz; Jeffrey Kuret; Diane Murphy; Larry Refolo
New directions for frontotemporal dementia drug discovery.
Alzheimer's & dementia : the journal of the Alzheimer's Association 2008;4(2):89-93.
2008: Edward Chang; Jeffrey Kuret
Detection and quantification of tau aggregation using a membrane filter assay.
Analytical biochemistry 2008;373(2):330-6.
2008: Theresa J Kannanayakal; Jerry R Mendell; Jeffrey Kuret
Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis.
Neuroscience letters 2008;431(2):141-5.
2007: Nicolette S Honson; Ronald L Johnson; Wenwei Huang; James Inglese; Christopher P Austin; Jeffrey Kuret
Differentiating Alzheimer disease-associated aggregates with small molecules.
Neurobiology of disease 2007;28(3):251-60.
2007: Nicolette S Honson; Jordan R Jensen; Michael V Darby; Jeffrey Kuret
Potent inhibition of tau fibrillization with a multivalent ligand.
Biochemical and biophysical research communications 2007;363(1):229-34.
2007: Erin E Congdon; Mihaela Necula; Robert D Blackstone; Jeffrey Kuret
Potency of a tau fibrillization inhibitor is influenced by its aggregation state.
Archives of biochemistry and biophysics 2007;465(1):127-35.
2007: Bhaswati Bandyopadhyay; Guibin Li; Haishan Yin; Jeffrey Kuret
Tau aggregation and toxicity in a cell culture model of tauopathy.
The Journal of biological chemistry 2007;282(22):16454-64.
2006: Theresa J Kannanayakal; Haiyang Tao; Dale D Vandre; Jeffrey Kuret
Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions.
Acta neuropathologica 2006;111(5):413-21.
2006: Haishan Yin; Kelly A Laguna; Guibin Li; Jeffrey Kuret
Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.
Biochemistry 2006;45(16):5297-308.
2006: Haishan Yin; Jeffrey Kuret
C-terminal truncation modulates both nucleation and extension phases of tau fibrillization.
FEBS letters 2006;580(1):211-5.
2005: Mihaela Necula; Carmen Chirita; Jeffrey Kuret
Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.
Biochemistry 2005;44(30):10227-37.
2005: Jeffrey Kuret; Erin E Congdon; Guibin Li; Haishan Yin; Xian Yu; Qi Zhong
Evaluating triggers and enhancers of tau fibrillization.
Microscopy research and technique 2005;67(3-4):141-55.
2005: Carmen Chirita; Erin E Congdon; Haishan Yin; Jeffrey Kuret
Triggers of full-length tau aggregation: a role for partially folded intermediates.
Biochemistry 2005;44(15):5862-72.
2005: Mihaela Necula; Jeffrey Kuret
Site-specific pseudophosphorylation modulates the rate of tau filament dissociation.
FEBS letters 2005;579(6):1453-7.
2005: Jeffrey Kuret; Carmen Chirita; Erin E Congdon; Theresa J Kannanayakal; Guibin Li; Mihaela Necula; Haishan Yin; Qi Zhong
Pathways of tau fibrillization.
Biochimica et biophysica acta 2005;1739(2-3):167-78.
2004: Mihaela Necula; Jeffrey Kuret
Pseudophosphorylation and glycation of tau protein enhance but do not trigger fibrillization in vitro.
The Journal of biological chemistry 2004;279(48):49694-703.
2004: Mihaela Necula; Jeffrey Kuret
A static laser light scattering assay for surfactant-induced tau fibrillization.
Analytical biochemistry 2004;333(2):205-15.
2004: Mihaela Necula; Jeffrey Kuret
Electron microscopy as a quantitative method for investigating tau fibrillization.
Analytical biochemistry 2004;329(2):238-46.
2004: Guibin Li; Haishan Yin; Jeffrey Kuret
Casein kinase 1 delta phosphorylates tau and disrupts its binding to microtubules.
The Journal of biological chemistry 2004;279(16):15938-45.
2004: Carmen Chirita; Mihaela Necula; Jeffrey Kuret
Ligand-dependent inhibition and reversal of tau filament formation.
Biochemistry 2004;43(10):2879-87.
2004: Carmen Chirita; Jeffrey Kuret
Evidence for an intermediate in tau filament formation.
Biochemistry 2004;43(6):1704-14.
2003: Mihaela Necula; Carmen Chirita; Jeffrey Kuret
Rapid anionic micelle-mediated alpha-synuclein fibrillization in vitro.
The Journal of biological chemistry 2003;278(47):46674-80.
2003: Carmen Chirita; Mihaela Necula; Jeffrey Kuret
Anionic micelles and vesicles induce tau fibrillization in vitro.
The Journal of biological chemistry 2003;278(28):25644-50.
2002: jiangzhou yu; Jeffrey Kuret; Mark M Rasenick
Transient expression of fluorescent tau proteins promotes process formation in PC12 cells: contributions of the tau C-terminus to this process.
Journal of neuroscience research 2002;67(5):625-33.
2001: Nupur Ghoshal; Francisco García-Sierra; Y Fu; Laurel Beckett; Elliott J Mufson; Jeffrey Kuret; Robert W Berry; Lester I Binder
Tau-66: evidence for a novel tau conformation in Alzheimer's disease.
Journal of neurochemistry 2001;77(5):1372-85.
2001: N Mashhoon; G Carmel; J W Pflugrath; Jeffrey Kuret
Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae.
Archives of biochemistry and biophysics 2001;387(1):11-9.
2000: T Chris Gamblin; ME King; Jeffrey Kuret; Robert W Berry; Lester I Binder
Oxidative regulation of fatty acid-induced tau polymerization.
Biochemistry 2000;39(46):14203-10.
2000: Aida Abraha; Nupur Ghoshal; T Chris Gamblin; Vincent L Cryns; Robert W Berry; Jeffrey Kuret; Lester I Binder
C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.
Journal of cell science 2000;113 Pt 21():3737-45.
2000: Claudia Schwab; AJ DeMaggio; Nupur Ghoshal; Lester I Binder; Jeffrey Kuret; Patrick L McGeer
Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases.
Neurobiology of aging 2000;21(4):503-10.
2000: N Mashhoon; AJ DeMaggio; V Tereshko; S C Bergmeier; M Egli; MF Hoekstra; Jeffrey Kuret
Crystal structure of a conformation-selective casein kinase-1 inhibitor.
The Journal of biological chemistry 2000;275(26):20052-60.
2000: T Chris Gamblin; ME King; Hana N. Dawson; Michael P. Vitek; Jeffrey Kuret; Robert W Berry; Lester I Binder
In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants.
Biochemistry 2000;39(20):6136-44.
2000: Koji Yasojima; Jeffrey Kuret; AJ DeMaggio; Edith G McGeer; Patrick L McGeer
Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain.
Brain research 2000;865(1):116-20.
2000: ME King; T Chris Gamblin; Jeffrey Kuret; Lester I Binder
Differential assembly of human tau isoforms in the presence of arachidonic acid.
Journal of neurochemistry 2000;74(4):1749-57.
1999: ME King; V Ahuja; Lester I Binder; Jeffrey Kuret
Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.
Biochemistry 1999;38(45):14851-9.
1999: Janusz Tucholski; Jeffrey Kuret; Gail Johnson
Tau is modified by tissue transglutaminase in situ: possible functional and metabolic effects of polyamination.
Journal of neurochemistry 1999;73(5):1871-80.
1999: Nupur Ghoshal; J F Smiley; AJ DeMaggio; MF Hoekstra; E J Cochran; Lester I Binder; Jeffrey Kuret
A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease.
The American journal of pathology 1999;155(4):1163-72.
1999: Estelle Sontag; Viyada Nunbhakdi-Craig; Gloria Lee; R Brandt; Craig Kamibayashi; Jeffrey Kuret; Charles L White; Marc C Mumby; George S Bloom
Molecular interactions among protein phosphatase 2A, tau, and microtubules. Implications for the regulation of tau phosphorylation and the development of tauopathies.
The Journal of biological chemistry 1999;274(36):25490-8.
1999: Ka Bian; K Davis; Jeffrey Kuret; L Binder; Ferid Murad
Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry.
The American journal of physiology 1999;277(1 Pt 2):F33-40.
1999: Ivana Vancurova; Jae H Choi; H Lin; Jeffrey Kuret; Ales Vancura
Regulation of phosphatidylinositol 4-phosphate 5-kinase from Schizosaccharomyces pombe by casein kinase I.
The Journal of biological chemistry 1999;274(2):1147-55.
1998: S N Prasanna Murthy; JH Wilson; TJ Lukas; Jeffrey Kuret; Laszlo Lorand
Cross-linking sites of the human tau protein, probed by reactions with human transglutaminase.
Journal of neurochemistry 1998;71(6):2607-14.
1997: Jeffrey Kuret; G S Johnson; D Cha; ER Christenson; AJ DeMaggio; MF Hoekstra
Casein kinase 1 is tightly associated with paired-helical filaments isolated from Alzheimer's disease brain.
Journal of neurochemistry 1997;69(6):2506-15.
1996: G Carmel; E M Mager; Lester I Binder; Jeffrey Kuret
The structural basis of monoclonal antibody Alz50's selectivity for Alzheimer's disease pathology.
The Journal of biological chemistry 1996;271(51):32789-95.
1996: X Wang; MF Hoekstra; AJ DeMaggio; N Dhillon; Ales Vancura; Jeffrey Kuret; Gerald C Johnston; Richard A Singer
Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase.
Molecular and cellular biology 1996;16(10):5375-85.
1996: Rui-Ming Xu; G Carmel; Jeffrey Kuret; Xiaodong Cheng
Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(13):6308-13.
1995: Rui-Ming Xu; G Carmel; R M Sweet; Jeffrey Kuret; Xiaodong Cheng
Crystal structure of casein kinase-1, a phosphate-directed protein kinase.
The EMBO journal 1995;14(5):1015-23.
1994: P H Kearney; M Ebert; Jeffrey Kuret
Molecular cloning and sequence analysis of two novel fission yeast casein kinase-1 isoforms.
Biochemical and biophysical research communications 1994;203(1):231-6.
1994: MF Hoekstra; N Dhillon; G Carmel; AJ DeMaggio; R A Lindberg; Tony Hunter; Jeffrey Kuret
Budding and fission yeast casein kinase I isoforms have dual-specificity protein kinase activity.
Molecular biology of the cell 1994;5(8):877-86.
1994: Ales Vancura; A Sessler; B Leichus; Jeffrey Kuret
A prenylation motif is required for plasma membrane localization and biochemical function of casein kinase I in budding yeast.
The Journal of biological chemistry 1994;269(30):19271-8.
1994: P C Wang; Ales Vancura; A Desai; G Carmel; Jeffrey Kuret
Cytoplasmic forms of fission yeast casein kinase-1 associate primarily with the particulate fraction of the cell.
The Journal of biological chemistry 1994;269(16):12014-23.
1994: G Carmel; B Leichus; Xiaodong Cheng; S D Patterson; U Mirza; Brian T Chait; Jeffrey Kuret
Expression, purification, crystallization, and preliminary x-ray analysis of casein kinase-1 from Schizosaccharomyces pombe.
The Journal of biological chemistry 1994;269(10):7304-9.
1993: Ales Vancura; A O'Connor; S D Patterson; U Mirza; Brian T Chait; Jeffrey Kuret
Isolation and properties of YCK2, a Saccharomyces cerevisiae homolog of casein kinase-1.
Archives of biochemistry and biophysics 1993;305(1):47-53.
1992: G Carmel; Jeffrey Kuret
A solid-phase screen for protein kinase substrate selectivity.
Analytical biochemistry 1992;203(2):274-80.
1992: P C Wang; Ales Vancura; T G Mitcheson; Jeffrey Kuret
Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1.
Molecular biology of the cell 1992;3(3):275-86.
1991: Jeffrey Kuret; J W Pflugrath
Crystallization and preliminary X-ray analysis of the cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae.
Biochemistry 1991;30(43):10595-600.
1988: Jeffrey Kuret; K E Johnson; C Nicolette; M J Zoller
Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit.
The Journal of biological chemistry 1988;263(19):9149-54.
1988: M J Zoller; Jeffrey Kuret; S Cameron; L Levin; K E Johnson
Purification and characterization of C1, the catalytic subunit of Saccharomyces cerevisiae cAMP-dependent protein kinase encoded by TPK1.
The Journal of biological chemistry 1988;263(19):9142-8.
1988: L R Levin; Jeffrey Kuret; K E Johnson; S Powers; S Cameron; T Michaeli; Michael Wigler; M J Zoller
A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation.
Science (New York, N.Y.) 1988;240(4848):68-70.
1986: Jeffrey Kuret; H Bell; P Cohen
Identification of high levels of protein phosphatase-1 in rat liver nuclei.
FEBS letters 1986;203(2):197-202.
1986: C F Holmes; Jeffrey Kuret; A A Chisholm; P Cohen
Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II.
Biochimica et biophysica acta 1986;870(3):408-16.
1985: H Schulman; Jeffrey Kuret; A B Jefferson; P S Nose; K H Spitzer
Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues.
Biochemistry 1985;24(20):5320-7.
1985: Jeffrey Kuret; J R Woodgett; P Cohen
Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Identification of the sites phosphorylated by casein kinase-I.
European journal of biochemistry / FEBS 1985;151(1):39-48.
1985: Jeffrey Kuret; H Schulman
Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase.
The Journal of biological chemistry 1985;260(10):6427-33.
1984: Jeffrey Kuret; H Schulman
Purification and characterization of a Ca2+/calmodulin-dependent protein kinase from rat brain.
Biochemistry 1984;23(23):5495-504.
1982: J Brown; D Heininger; Jeffrey Kuret; Y Mullen
Normal response to pregnancy in rats cured of streptozotocin diabetes by transplantation of one fetal pancreas.
Diabetologia 1982;22(4):273-5.
1981: J Brown; D Heininger; Jeffrey Kuret; Y Mullen
Islet cells grow after transplantation of fetal pancreas and control of diabetes.
Diabetes 1981;30(1):9-13.