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Gail Johnson

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Wanjoo Chun; Geoffrey S Waldo; Gail Johnson
Split GFP complementation assay for quantitative measurement of tau aggregation in situ.
A J Filiano; Janusz Tucholski; P J Dolan; G Colak; Gail Johnson
Transglutaminase 2 protects against ischemic stroke.
Philip J Dolan; Gail Johnson
A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.

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All Publications

2011: Wanjoo Chun; Geoffrey S Waldo; Gail Johnson
Split GFP complementation assay for quantitative measurement of tau aggregation in situ.
Methods in molecular biology (Clifton, N.J.) 2011;670():109-23.
2010: A J Filiano; Janusz Tucholski; P J Dolan; G Colak; Gail Johnson
Transglutaminase 2 protects against ischemic stroke.
Neurobiology of disease 2010;39(3):334-43.
2010: Philip J Dolan; Gail Johnson
A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.
The Journal of biological chemistry 2010;285(29):21978-87.
2009: Rodrigo A Quintanilla; Gail Johnson
Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease.
Brain research bulletin 2009;80(4-5):242-7.
2009: Rodrigo A Quintanilla; Tori A Matthews-Roberson; Philip J Dolan; Gail Johnson
Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease.
The Journal of biological chemistry 2009;284(28):18754-66.
2009: Pil-Jae Kong; Myung-Og Kil; Heejae Lee; Sung-Soo Kim; Gail Johnson; Wanjoo Chun
Increased expression of Bim contributes to the potentiation of serum deprivation-induced apoptotic cell death in Huntington's disease knock-in striatal cell line.
Neurological research 2009;31(1):77-83.
2009: Soner Gundemir; Gail Johnson
Intracellular localization and conformational state of transglutaminase 2: implications for cell death.
PloS one 2009;4(7):e6123.
2008: Tori A Matthews-Roberson; Rodrigo A Quintanilla; Huiping Ding; Gail Johnson
Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death.
Brain research 2008;1234():206-12.
2008: Rodrigo A Quintanilla; Youngnam N Jin; Karen Fuenzalida; Miguel Bronfman; Gail Johnson
Rosiglitazone treatment prevents mitochondrial dysfunction in mutant huntingtin-expressing cells: possible role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in the pathogenesis of Huntington disease.
The Journal of biological chemistry 2008;283(37):25628-37.
2008: Huiping Ding; Philip J Dolan; Gail Johnson
Histone deacetylase 6 interacts with the microtubule-associated protein tau.
Journal of neurochemistry 2008;106(5):2119-30.
2008: Huiping Ding; Gail Johnson
The last tangle of tau.
Journal of Alzheimer's disease : JAD 2008;14(4):441-7.
2008: Huiping Ding; Gail Johnson
New application of beta-galactosidase complementation to monitor tau self-association.
Journal of neurochemistry 2008;106(4):1545-51.
2008: Anthony J Filiano; Craig D C Bailey; Janusz Tucholski; Soner Gundemir; Gail Johnson
Transglutaminase 2 protects against ischemic insult, interacts with HIF1beta, and attenuates HIF1 signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):2662-75.
2007: Wanjoo Chun; Geoffrey Waldo; Gail Johnson
Split GFP complementation assay: a novel approach to quantitatively measure aggregation of tau in situ: effects of GSK3beta activation and caspase 3 cleavage.
Journal of neurochemistry 2007;103(6):2529-39.
2007: Paramita Mookherjee; Rodrigo A Quintanilla; Myoung-Sun Roh; Anna A Zmijewska; Richard Scott Jope; Gail Johnson
Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death.
Journal of cellular biochemistry 2007;102(1):196-210.
2007: Wanjoo Chun; Gail Johnson
Activation of glycogen synthase kinase 3beta promotes the intermolecular association of tau. The use of fluorescence resonance energy transfer microscopy.
The Journal of biological chemistry 2007;282(32):23410-7.
2007: Qingmin Ruan; Rodrigo A Quintanilla; Gail Johnson
Type 2 transglutaminase differentially modulates striatal cell death in the presence of wild type or mutant huntingtin.
Journal of neurochemistry 2007;102(1):25-36.
2007: Jesse M Hunter; Mathieu Lesort; Gail Johnson
Ubiquitin-proteasome system alterations in a striatal cell model of Huntington's disease.
Journal of neuroscience research 2007;85(8):1774-88.
2007: Kaihong Mi; Gail Johnson
Regulated proteolytic processing of LRP6 results in release of its intracellular domain.
Journal of neurochemistry 2007;101(2):517-29.
2007: Qingmin Ruan; Gail Johnson
Transglutaminase 2 in neurodegenerative disorders.
Frontiers in bioscience : a journal and virtual library 2007;12():891-904.
2007: Wanjoo Chun; Gail Johnson
The role of tau phosphorylation and cleavage in neuronal cell death.
Frontiers in bioscience : a journal and virtual library 2007;12():733-56.
2006: Kaihong Mi; Gail Johnson
The role of tau phosphorylation in the pathogenesis of Alzheimer's disease.
Current Alzheimer research 2006;3(5):449-63.
2006: Buffie J Clodfelder-Miller; Anna A Zmijewska; Gail Johnson; Richard Scott Jope
Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency.
Diabetes 2006;55(12):3320-5.
2006: Tamara Milakovic; Rodrigo A Quintanilla; Gail Johnson
Mutant huntingtin expression induces mitochondrial calcium handling defects in clonal striatal cells: functional consequences.
The Journal of biological chemistry 2006;281(46):34785-95.
2006: Huiping Ding; Tori A Matthews; Gail Johnson
Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation.
The Journal of biological chemistry 2006;281(28):19107-14.
2006: Craig D C Bailey; Gail Johnson
The protective effects of cystamine in the R6/2 Huntington's disease mouse involve mechanisms other than the inhibition of tissue transglutaminase.
Neurobiology of aging 2006;27(6):871-9.
2006: Janusz Tucholski; Kevin A Roth; Gail Johnson
Tissue transglutaminase overexpression in the brain potentiates calcium-induced hippocampal damage.
Journal of neurochemistry 2006;97(2):582-94.
2006: Kaihong Mi; Philip J Dolan; Gail Johnson
The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity.
The Journal of biological chemistry 2006;281(8):4787-94.
2006: Gail Johnson
Tau phosphorylation and proteolysis: insights and perspectives.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):243-50.
2005: Jeremy M van Raamsdonk; Jacqueline Pearson; Craig D C Bailey; Daniel A Rogers; Gail Johnson; Michael R Hayden; Blair R Leavitt
Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease.
Journal of neurochemistry 2005;95(1):210-20.
2005: Yeun Su Choo; Zhengkuan Mao; Gail Johnson; Mathieu Lesort
Increased glutathione levels in cortical and striatal mitochondria of the R6/2 Huntington's disease mouse model.
Neuroscience letters 2005;386(1):63-8.
2005: Tamara Milakovic; Gail Johnson
Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin.
The Journal of biological chemistry 2005;280(35):30773-82.
2005: Tori A Matthews; Gail Johnson
14-3-3Zeta does not increase GSK3beta-mediated tau phosphorylation in cell culture models.
Neuroscience letters 2005;384(3):211-6.
2005: Jesse M Hunter; Andrew B Crouse; Mathieu Lesort; Gail Johnson; Peter J Detloff
Verification of somatic CAG repeat expansion by pre-PCR fractionation.
Journal of neuroscience methods 2005;144(1):11-7.
2005: Kaihong Mi; Gail Johnson
Role of the intracellular domains of LRP5 and LRP6 in activating the Wnt canonical pathway.
Journal of cellular biochemistry 2005;95(2):328-38.
2005: William H Stoothoff; Jae-Hyeon Cho; Roy P McDonald; Gail Johnson
FRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylation.
The Journal of biological chemistry 2005;280(1):270-6.
2005: William H Stoothoff; Gail Johnson
Tau phosphorylation: physiological and pathological consequences.
Biochimica et biophysica acta 2005;1739(2-3):280-97.
2005: Craig D C Bailey; Janusz Tucholski; Gail Johnson
Transglutaminases in neurodegenerative disorders.
Progress in experimental tumor research 2005;38():139-57.
2005: Craig D C Bailey; Gail Johnson
Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms.
Journal of neurochemistry 2005;92(1):83-92.
2004: Jae-Hyeon Cho; Gail Johnson
Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ.
The Journal of biological chemistry 2004;279(52):54716-23.
2004: Craig D C Bailey; Gail Johnson
Developmental regulation of tissue transglutaminase in the mouse forebrain.
Journal of neurochemistry 2004;91(6):1369-79.
2004: Gail Johnson; William H Stoothoff
Tau phosphorylation in neuronal cell function and dysfunction.
Journal of cell science 2004;117(Pt 24):5721-9.
2004: Myung-Duk Suh; Chang-Ha Park; Sung-Soo Kim; Myeng-Og Kil; Geon-Hee Lee; Gail Johnson; Wanjoo Chun
Tissue transglutaminase is not involved in the aggregate formation of stably expressed alpha-synuclein in SH-SY5Y human neuroblastoma cells.
Archives of pharmacal research 2004;27(8):850-6.
2004: Yeun Su Choo; Gail Johnson; Marcy E MacDonald; Peter J Detloff; Mathieu Lesort
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
Human molecular genetics 2004;13(14):1407-20.
2004: Gail Johnson; Reginald LeShoure
Immunoblot analysis reveals that isopeptide antibodies do not specifically recognize the epsilon-(gamma-glutamyl)lysine bonds formed by transglutaminase activity.
Journal of neuroscience methods 2004;134(2):151-8.
2004: Shirley B Shelton; Pavan K Krishnamurthy; Gail Johnson
Effects of cyclin-dependent kinase-5 activity on apoptosis and tau phosphorylation in immortalized mouse brain cortical cells.
Journal of neuroscience research 2004;76(1):110-20.
2004: Qingmin Ruan; Mathieu Lesort; Marcy E MacDonald; Gail Johnson
Striatal cells from mutant huntingtin knock-in mice are selectively vulnerable to mitochondrial complex II inhibitor-induced cell death through a non-apoptotic pathway.
Human molecular genetics 2004;13(7):669-81.
2004: Tamara Milakovic; Janusz Tucholski; Eric McCoy; Gail Johnson
Intracellular localization and activity state of tissue transglutaminase differentially impacts cell death.
The Journal of biological chemistry 2004;279(10):8715-22.
2004: Craig D C Bailey; Robert M Graham; Nisha Nanda; Peter J A Davies; Gail Johnson
Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases.
Molecular and cellular neurosciences 2004;25(3):493-503.
2004: Shirley B Shelton; Gail Johnson
Cyclin-dependent kinase-5 in neurodegeneration.
Journal of neurochemistry 2004;88(6):1313-26.
2004: Pavan K Krishnamurthy; Gail Johnson
Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model.
The Journal of biological chemistry 2004;279(9):7893-900.
2004: Richard Scott Jope; Gail Johnson
The glamour and gloom of glycogen synthase kinase-3.
Trends in biochemical sciences 2004;29(2):95-102.
2004: Jae-Hyeon Cho; Gail Johnson
Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3beta (GSK3beta) plays a critical role in regulating tau's ability to bind and stabilize microtubules.
Journal of neurochemistry 2004;88(2):349-58.
2003: Gail Johnson; Craig D C Bailey
The p38 MAP kinase signaling pathway in Alzheimer's disease.
Experimental neurology 2003;183(2):263-8.
2003: Janusz Tucholski; Gail Johnson
Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation.
The Journal of biological chemistry 2003;278(29):26838-43.
2003: Mathieu Lesort; Matthew Lee; Janusz Tucholski; Gail Johnson
Cystamine inhibits caspase activity. Implications for the treatment of polyglutamine disorders.
The Journal of biological chemistry 2003;278(6):3825-30.
2003: Jae-Hyeon Cho; Gail Johnson
Glycogen synthase kinase 3beta phosphorylates tau at both primed and unprimed sites. Differential impact on microtubule binding.
The Journal of biological chemistry 2003;278(1):187-93.
2002: Wanjoo Chun; Mathieu Lesort; Matthew Lee; Gail Johnson
Transient osmotic stress facilitates mutant huntingtin aggregation.
Neuroreport 2002;13(18):2543-6.
2002: William H Stoothoff; Craig D C Bailey; Kaihong Mi; Sheng-Cai Lin; Gail Johnson
Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta.
Journal of neurochemistry 2002;83(4):904-13.
2002: Gail Johnson; Craig D C Bailey
Tau, where are we now?
Journal of Alzheimer's disease : JAD 2002;4(5):375-98.
2002: Jianwen Zhang; Chi-Hao Luan; Kuo-Chen Chou; Gail Johnson
Identification of the N-terminal functional domains of Cdk5 by molecular truncation and computer modeling.
Proteins 2002;48(3):447-53.
2002: Piyajit Watcharasit; Gautam N Bijur; Jaroslaw W Zmijewski; Ling Song; Anna A Zmijewska; Xinbin Chen; Gail Johnson; Richard Scott Jope
Direct, activating interaction between glycogen synthase kinase-3beta and p53 after DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):7951-5.
2002: Janusz Tucholski; Gail Johnson
Tissue transglutaminase differentially modulates apoptosis in a stimuli-dependent manner.
Journal of neurochemistry 2002;81(4):780-91.
2002: Jianwen Zhang; Pavan K Krishnamurthy; Gail Johnson
Cdk5 phosphorylates p53 and regulates its activity.
Journal of neurochemistry 2002;81(2):307-13.
2002: Wanjoo Chun; Mathieu Lesort; Matthew Lee; Gail Johnson
Mutant huntingtin aggregates do not sensitize cells to apoptotic stressors.
FEBS letters 2002;515(1-3):61-5.
2002: Mathieu Lesort; Wanjoo Chun; Janusz Tucholski; Gail Johnson
Does tissue transglutaminase play a role in Huntington's disease?
Neurochemistry international 2002;40(1):37-52.
2001: P Mookherjee; Gail Johnson
Tau phosphorylation during apoptosis of human SH-SY5Y neuroblastoma cells.
Brain research 2001;921(1-2):31-43.
2001: Shirley B Shelton; Gail Johnson
Tau and HMW tau phosphorylation and compartmentalization in apoptotic neuronal PC12 cells.
Journal of neuroscience research 2001;66(2):203-13.
2001: William H Stoothoff; Gail Johnson
Hyperosmotic stress-induced apoptosis and tau phosphorylation in human neuroblastoma cells.
Journal of neuroscience research 2001;65(6):573-82.
2001: Yong Shen; Lih-Fen Lue; L Yang; Alex Roher; Y Kuo; R Strohmeyer; W J Goux; Virginia M-Y Lee; Gail Johnson; S D Webster; N R Cooper; Bonnie M Bradt; Joseph Rogers
Complement activation by neurofibrillary tangles in Alzheimer's disease.
Neuroscience letters 2001;305(3):165-8.
2001: JA Hartigan; Wencheng Xiong; Gail Johnson
Glycogen synthase kinase 3beta is tyrosine phosphorylated by PYK2.
Biochemical and biophysical research communications 2001;284(2):485-9.
2001: Patrizia De Sarno; Mathieu Lesort; Gautam N Bijur; Gail Johnson; Richard Scott Jope
Cholinergic- and stress-induced signaling activities in cells overexpressing wild-type and mutant presenilin-1.
Brain research 2001;903(1-2):226-30.
2001: Wanjoo Chun; Mathieu Lesort; Janusz Tucholski; P W Faber; Marcy E MacDonald; Christopher A Ross; Gail Johnson
Tissue transglutaminase selectively modifies proteins associated with truncated mutant huntingtin in intact cells.
Neurobiology of disease 2001;8(3):391-404.
2001: Wanjoo Chun; Mathieu Lesort; Janusz Tucholski; Christopher A Ross; Gail Johnson
Tissue transglutaminase does not contribute to the formation of mutant huntingtin aggregates.
The Journal of cell biology 2001;153(1):25-34.
2001: andy grierson; Gail Johnson; Christopher C J Miller
Three different human tau isoforms and rat neurofilament light, middle and heavy chain proteins are cellular substrates for transglutaminase.
Neuroscience letters 2001;298(1):9-12.
2001: Janusz Tucholski; Mathieu Lesort; Gail Johnson
Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells.
Neuroscience 2001;102(2):481-91.
2000: J Zhang; Gail Johnson
Tau protein is hyperphosphorylated in a site-specific manner in apoptotic neuronal PC12 cells.
Journal of neurochemistry 2000;75(6):2346-57.
2000: Mathieu Lesort; Janusz Tucholski; J Zhang; Gail Johnson
Impaired mitochondrial function results in increased tissue transglutaminase activity in situ.
Journal of neurochemistry 2000;75(5):1951-61.
2000: Pavan K Krishnamurthy; Jimmy Mays; Gautam N Bijur; Gail Johnson
Transient oxidative stress in SH-SY5Y human neuroblastoma cells results in caspase dependent and independent cell death and tau proteolysis.
Journal of neuroscience research 2000;61(5):515-23.
2000: Mathieu Lesort; Janusz Tucholski; ML Miller; Gail Johnson
Tissue transglutaminase: a possible role in neurodegenerative diseases.
Progress in neurobiology 2000;61(5):439-63.
2000: Sheri M Jenkins; Gail Johnson
Microtubule/MAP-affinity regulating kinase (MARK) is activated by phenylarsine oxide in situ and phosphorylates tau within its microtubule-binding domain.
Journal of neurochemistry 2000;74(4):1463-8.
2000: Sheri M Jenkins; MD Zinnerman; C Garner; Gail Johnson
Modulation of tau phosphorylation and intracellular localization by cellular stress.
The Biochemical journal 2000;345 Pt 2():263-70.
2000: Mathieu Lesort; Gail Johnson
Insulin-like growth factor-1 and insulin mediate transient site-selective increases in tau phosphorylation in primary cortical neurons.
Neuroscience 2000;99(2):305-16.
2000: Rodney P Guttmann; Gail Johnson
Measurement of calpain activity in vitro and in situ using a fluorescent compound and tau as substrates.
Methods in molecular biology (Clifton, N.J.) 2000;144():143-50.
1999: PK Davis; Gail Johnson
The microtubule binding of Tau and high molecular weight Tau in apoptotic PC12 cells is impaired because of altered phosphorylation.
The Journal of biological chemistry 1999;274(50):35686-92.
1999: Gail Johnson; JA Hartigan
Tau protein in normal and Alzheimer's disease brain: an update.
Journal of Alzheimer's disease : JAD 1999;1(4-5):329-51.
1999: Gail Johnson; Sheri M Jenkins
Tau protein in normal and Alzheimer's disease brain.
Journal of Alzheimer's disease : JAD 1999;1(4-5):307-28.
1999: Mathieu Lesort; Wanjoo Chun; Gail Johnson; Robert J Ferrante
Tissue transglutaminase is increased in Huntington's disease brain.
Journal of neurochemistry 1999;73(5):2018-27.
1999: Janusz Tucholski; Jeffrey Kuret; Gail Johnson
Tau is modified by tissue transglutaminase in situ: possible functional and metabolic effects of polyamination.
Journal of neurochemistry 1999;73(5):1871-80.
1999: Sheri M Jenkins; Gail Johnson
Modulation of tau phosphorylation within its microtubule-binding domain by cellular thiols.
Journal of neurochemistry 1999;73(5):1843-50.
1999: J Zhang; Janusz Tucholski; Mathieu Lesort; Richard Scott Jope; Gail Johnson
Novel bimodal effects of the G-protein tissue transglutaminase on adrenoreceptor signalling.
The Biochemical journal 1999;343 Pt 3():541-9.
1999: ML Miller; Gail Johnson
Rapid, single-step procedure for the identification of transglutaminase-mediated isopeptide crosslinks in amino acid digests.
Journal of chromatography. B, Biomedical sciences and applications 1999;732(1):65-72.
1999: JA Hartigan; Gail Johnson
Transient increases in intracellular calcium result in prolonged site-selective increases in Tau phosphorylation through a glycogen synthase kinase 3beta-dependent pathway.
The Journal of biological chemistry 1999;274(30):21395-401.
1999: PK Davis; Gail Johnson
Energy metabolism and protein phosphorylation during apoptosis: a phosphorylation study of tau and high-molecular-weight tau in differentiated PC12 cells.
The Biochemical journal 1999;340 ( Pt 1)():51-8.
1999: Kenneth Hensley; Robert A Floyd; N Y Zheng; R Nael; KA Robinson; X Nguyen; Quentin N Pye; Charles A Stewart; James W Geddes; William R Markesbery; E Patel; Gail Johnson; G Bing
p38 kinase is activated in the Alzheimer's disease brain.
Journal of neurochemistry 1999;72(5):2053-8.
1999: N A Mashburn; Menjor Tino Unlap; J Runquist; A Alderman; Gail Johnson; Phillip Darwin Bell
Altered protein kinase C activation of Na+/Ca2+ exchange in mesangial cells from salt-sensitive rats.
The American journal of physiology 1999;276(4 Pt 2):F574-80.
1999: Nancy J Woolf; MD Zinnerman; Gail Johnson
Hippocampal microtubule-associated protein-2 alterations with contextual memory.
Brain research 1999;821(1):241-9.
1999: Mathieu Lesort; Richard Scott Jope; Gail Johnson
Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase.
Journal of neurochemistry 1999;72(2):576-84.
1999: Mathieu Lesort; A Greendorfer; Craig A Stockmeier; Gail Johnson; Richard Scott Jope
Glycogen synthase kinase-3beta, beta-catenin, and tau in postmortem bipolar brain.
Journal of neural transmission (Vienna, Austria : 1996) 1999;106(11-12):1217-22.
1998: N Spear; Alvaro G Estévez; Gail Johnson; Dale E Bredesen; John A Thompson; Joseph S Beckman
Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2.
Archives of biochemistry and biophysics 1998;356(1):41-5.
1998: H Q Xie; Gail Johnson
Calcineurin inhibition prevents calpain-mediated proteolysis of tau in differentiated PC12 cells.
Journal of neuroscience research 1998;53(2):153-64.
1998: H Xie; J M Litersky; JA Hartigan; Richard Scott Jope; Gail Johnson
The interrelationship between selective tau phosphorylation and microtubule association.
Brain research 1998;798(1-2):173-83.
1998: J Zhang; RP Guttmann; Gail Johnson
Tissue transglutaminase is an in situ substrate of calpain: regulation of activity.
Journal of neurochemistry 1998;71(1):240-7.
1998: RP Guttmann; Gail Johnson
Oxidative stress inhibits calpain activity in situ.
The Journal of biological chemistry 1998;273(21):13331-8.
1998: Mathieu Lesort; K Attanavanich; J Zhang; Gail Johnson
Distinct nuclear localization and activity of tissue transglutaminase.
The Journal of biological chemistry 1998;273(20):11991-4.
1998: J Zhang; Mathieu Lesort; RP Guttmann; Gail Johnson
Modulation of the in situ activity of tissue transglutaminase by calcium and GTP.
The Journal of biological chemistry 1998;273(4):2288-95.
1998: Sheri M Jenkins; Gail Johnson
Tau complexes with phospholipase C-gamma in situ.
Neuroreport 1998;9(1):67-71.
1997: Gail Johnson; RP Guttmann
Calpains: intact and active?
BioEssays : news and reviews in molecular, cellular and developmental biology 1997;19(11):1011-8.
1997: Sheri M Jenkins; Gail Johnson
Phosphorylation of microtubule-associated protein tau on Ser 262 by an embryonic 100 kDa protein kinase.
Brain research 1997;767(2):305-13.
1997: H Xie; Gail Johnson
Ceramide selectively decreases tau levels in differentiated PC12 cells through modulation of calpain I.
Journal of neurochemistry 1997;69(3):1020-30.
1997: N Spear; Alvaro G Estévez; Luis Barbeito; Joseph S Beckman; Gail Johnson
Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase.
Journal of neurochemistry 1997;69(1):53-9.
1997: PK Davis; S M Dudek; Gail Johnson
Select alterations in protein kinases and phosphatases during apoptosis of differentiated PC12 cells.
Journal of neurochemistry 1997;68(6):2338-47.
1997: Gail Johnson; T M Cox; J P Lockhart; MD Zinnerman; ML Miller; Richard E Powers
Transglutaminase activity is increased in Alzheimer's disease brain.
Brain research 1997;751(2):323-9.
1997: RP Guttmann; J S Elce; Phillip Darwin Bell; J C Isbell; Gail Johnson
Oxidation inhibits substrate proteolysis by calpain I but not autolysis.
The Journal of biological chemistry 1997;272(3):2005-12.
1997: Gail Johnson; Peter Seubert; T M Cox; Ruth Motter; J P Brown; Douglas Galasko
The tau protein in human cerebrospinal fluid in Alzheimer's disease consists of proteolytically derived fragments.
Journal of neurochemistry 1997;68(1):430-3.
1996: C S Arnold; Gail Johnson; Robert N Cole; D L Dong; Michael K Lee; Gerald W Hart
The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine.
The Journal of biological chemistry 1996;271(46):28741-4.
1996: J M Litersky; Gail Johnson; R Jakes; Michel Goedert; Michael K Lee; Peter Seubert
Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356.
The Biochemical journal 1996;316 ( Pt 2)():655-60.
1996: L M Fleming; Karl H Weisgraber; Warren J Strittmatter; Juan C Troncoso; Gail Johnson
Differential binding of apolipoprotein E isoforms to tau and other cytoskeletal proteins.
Experimental neurology 1996;138(2):252-60.
1995: S M Dudek; Gail Johnson
Postnatal changes in serine/threonine protein phosphatases and their association with the microtubules.
Brain research. Developmental brain research 1995;90(1-2):54-61.
1995: M L Miller; Gail Johnson
Transglutaminase cross-linking of the tau protein.
Journal of neurochemistry 1995;65(4):1760-70.
1995: J A Greenwood; Gail Johnson
Localization and in situ phosphorylation state of nuclear tau.
Experimental cell research 1995;220(2):332-7.
1995: Peter Seubert; M Mawal-Dewan; Robin Barbour; R Jakes; Michel Goedert; Gail Johnson; J M Litersky; Dale Schenk; I Lieberburg; John Q Trojanowski
Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.
The Journal of biological chemistry 1995;270(32):18917-22.
1995: J M Litersky; Gail Johnson
Phosphorylation of tau in situ: inhibition of calcium-dependent proteolysis.
Journal of neurochemistry 1995;65(2):903-11.
1995: L M Fleming; Gail Johnson
Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP.
The Biochemical journal 1995;309 ( Pt 1)():41-7.
1995: Juan C Troncoso; A C Costello; J H Kim; Gail Johnson
Metal-catalyzed oxidation of bovine neurofilaments in vitro.
Free radical biology & medicine 1995;18(5):891-9.
1995: RP Guttmann; A C Erickson; Gail Johnson
Tau self-association: stabilization with a chemical cross-linker and modulation by phosphorylation and oxidation state.
Journal of neurochemistry 1995;64(3):1209-15.
1994: P K Davis; Gail Johnson
Monoclonal antibody Alz-50 reacts with bovine and human serum albumin.
Journal of neuroscience research 1994;39(5):589-94.
1994: S G Norman; Gail Johnson
Compromised mitochondrial function results in dephosphorylation of tau through a calcium-dependent process in rat brain cerebral cortical slices.
Neurochemical research 1994;19(9):1151-8.
1994: S M Dudek; Gail Johnson
Transglutaminase facilitates the formation of polymers of the beta-amyloid peptide.
Brain research 1994;651(1-2):129-33.
1994: Nancy J Woolf; S L Young; Gail Johnson; Michael S Fanselow
Pavlovian conditioning alters cortical microtubule-associated protein-2.
Neuroreport 1994;5(9):1045-8.
1994: J A Greenwood; C W Scott; R C Spreen; C B Caputo; Gail Johnson
Casein kinase II preferentially phosphorylates human tau isoforms containing an amino-terminal insert. Identification of threonine 39 as the primary phosphate acceptor.
The Journal of biological chemistry 1994;269(6):4373-80.
1993: S M Dudek; Gail Johnson
Transglutaminase catalyzes the formation of sodium dodecyl sulfate-insoluble, Alz-50-reactive polymers of tau.
Journal of neurochemistry 1993;61(3):1159-62.
1993: J A Greenwood; Juan C Troncoso; A C Costello; Gail Johnson
Phosphorylation modulates calpain-mediated proteolysis and calmodulin binding of the 200-kDa and 160-kDa neurofilament proteins.
Journal of neurochemistry 1993;61(1):191-9.
1993: Juan C Troncoso; A Costello; A L Watson; Gail Johnson
In vitro polymerization of oxidized tau into filaments.
Brain research 1993;613(2):313-6.
1993: Gail Johnson; V G Foley
Calpain-mediated proteolysis of microtubule-associated protein 2 (MAP-2) is inhibited by phosphorylation by cAMP-dependent protein kinase, but not by Ca2+/calmodulin-dependent protein kinase II.
Journal of neuroscience research 1993;34(6):642-7.
1993: A C Erickson; Gail Johnson
Metal (Fe3+) affinity chromatography: differential adsorption of tau phosphoproteins.
Journal of neuroscience methods 1993;46(3):245-9.
1993: J M Litersky; C W Scott; Gail Johnson
Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms.
Brain research 1993;604(1-2):32-40.
1992: Gail Johnson; Richard Scott Jope
The role of microtubule-associated protein 2 (MAP-2) in neuronal growth, plasticity, and degeneration.
Journal of neuroscience research 1992;33(4):505-12.
1992: Gail Johnson
Differential phosphorylation of tau by cyclic AMP-dependent protein kinase and Ca2+/calmodulin-dependent protein kinase II: metabolic and functional consequences.
Journal of neurochemistry 1992;59(6):2056-62.
1992: S Khilko; J A Greenwood; Gail Johnson
Brain casein kinase 2: affinity purification procedure using immobilized polyethylenimine.
Protein expression and purification 1992;3(5):355-61.
1992: J M Litersky; Gail Johnson
Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain.
The Journal of biological chemistry 1992;267(3):1563-8.
1992: Richard Scott Jope; Gail Johnson
Neurotoxic effects of dietary aluminium.
Ciba Foundation symposium 1992;169():254-62; discussion 262-7.
1992: Gail Johnson; A L Watson; R Lartius; Etsuro Uemura; Richard Scott Jope
Dietary aluminum selectively decreases MAP-2 in brains of developing and adult rats.
Neurotoxicology 1992;13(2):463-74.
1992: K Kolasa; Richard Scott Jope; MS Baird; Gail Johnson
Alterations of choline acetyltransferase, phosphoinositide hydrolysis, and cytoskeletal proteins in rat brain in response to colchicine administration.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1992;89(3):496-500.
1991: Gail Johnson; J M Litersky; John N Whitaker
Proteolysis of microtubule-associated protein 2 and tubulin by cathepsin D.
Journal of neurochemistry 1991;57(5):1577-83.
1991: Richard Scott Jope; Gail Johnson; MS Baird
Seizure-induced protein tyrosine phosphorylation in rat brain regions.
Epilepsia 1991;32(6):755-60.
1991: Gail Johnson; J A Greenwood; A C Costello; Juan C Troncoso
The regulatory role of calmodulin in the proteolysis of individual neurofilament proteins by calpain.
Neurochemical research 1991;16(8):869-73.
1991: Gail Johnson; J M Litersky; Richard Scott Jope
Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study.
Journal of neurochemistry 1991;56(5):1630-8.
1990: Gail Johnson; K W Cogdill; Richard Scott Jope
Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brain.
Neurobiology of aging 1990;11(3):209-16.
1989: Gail Johnson; Richard Scott Jope; L I Binder
Proteolysis of tau by calpain.
Biochemical and biophysical research communications 1989;163(3):1505-11.
1989: Gail Johnson; X H Li; Richard Scott Jope
Aluminum increases agonist-stimulated cyclic AMP production in rat cerebral cortical slices.
Journal of neurochemistry 1989;53(1):258-63.
1988: Gail Johnson
The effects of aluminum on agonist-induced alterations in cyclic AMP and cyclic GMP concentrations in rat brain regions in vivo.
Toxicology 1988;51(2-3):299-308.
1988: Gail Johnson; M Simonato; Richard Scott Jope
Dose- and time-dependent hippocampal cholinergic lesions induced by ethylcholine mustard aziridinium ion: effects of nerve growth factor, GM1 ganglioside, and vitamin E.
Neurochemical research 1988;13(8):685-92.
1988: Gail Johnson; Richard Scott Jope
Phosphorylation of rat brain cytoskeletal proteins is increased after orally administered aluminum.
Brain research 1988;456(1):95-103.
1987: Richard Scott Jope; T L Casebolt; Gail Johnson
Modulation of carbachol-stimulated inositol phospholipid hydrolysis in rat cerebral cortex.
Neurochemical research 1987;12(8):693-700.
1987: T L Stanton; Gail Johnson
In vitro measurements of cholinergic activity in brain regions of hibernating ground squirrels.
Brain research bulletin 1987;18(5):663-7.
1987: Gail Johnson; Richard Scott Jope
Aluminum alters cyclic AMP and cyclic GMP levels but not presynaptic cholinergic markers in rat brain in vivo.
Brain research 1987;403(1):1-6.
1986: Gail Johnson; Richard Scott Jope
Aluminum increases cyclic AMP in rat cerebral cortex in vivo.
Life sciences 1986;39(14):1301-5.
1986: Gail Johnson; Richard Scott Jope
Aluminum impairs glucose utilization and cholinergic activity in rat brain in vitro.
Toxicology 1986;40(1):93-102.
1986: D L Freerksen; N A Schroedl; Gail Johnson; C R Hartzell
Increased aerobic glucose oxidation by cAMP in cultured regenerated skeletal myotubes.
The American journal of physiology 1986;250(5 Pt 1):C713-9.
1986: Richard Scott Jope; Gail Johnson
Quinacrine and 2-(4-phenylpiperidino)cyclohexanol (AH5183) inhibit acetylcholine release and synthesis in rat brain slices.
Molecular pharmacology 1986;29(1):45-51.
1985: Gail Johnson; C R Hartzell
Halothane-induced alterations of glucose and pyruvate metabolism in rat cerebra synaptosomes.
Journal of neurochemistry 1985;44(6):1838-44.
1985: C R Hartzell; Gail Johnson
In vivo MAC values and in vitro experimentation.
Anesthesia and analgesia 1985;64(4):386-7.
1985: Gail Johnson; C R Hartzell
Choline uptake, acetylcholine synthesis and release, and halothane effects in synaptosomes.
Anesthesia and analgesia 1985;64(4):395-9.