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Paul Sijens
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45
Oudkerk, Matthijs
12
van Spronsen, Francjan
12
Irwan, Roy
9
Meiners, Linda
8
Potze, Jan Hendrik
7
Mostert, Jop
7
De Keyser, Jacques
6
Verbruggen, Krijn
5
Soorani-Lunsing, Roelineke
5
Breteler, Monique
5
Hofman, Albert
5
Dagnelie, Pieter
4
Den Heijer, Tom
4
Kappert, Peter
4
Ng, TC
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All Publications
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2009: Sijens P E; Westerlaan H E; de Groot J C; Boon M; Potze J H; van Spronsen F J; Lunsing R J; Oudkerk M
MR spectroscopy and diffusion tensor imaging of the brain in Sjögren-Larsson syndrome.
Molecular genetics and metabolism 2009;98(4):367-71.
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2009: Sijens Paul E
Parametric exploration of the liver by magnetic resonance methods.
European radiology 2009;19(11):2594-607.
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2009: Verbruggen Krijn T; Maurits Natasha M; Meiners Linda C; Brouwer Oebele F; van Spronsen Francjan J; Sijens Paul E
Quantitative multivoxel proton spectroscopy of the brain in developmental delay.
Journal of magnetic resonance imaging : JMRI 2009;30(4):716-21.
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2009: Viddeleer Alain R; Sijens Paul E; van Ooijen Peter M A; Kuypers Paul D L; Hovius Steven E R; Oudkerk Matthijs
Long-term reproducibility of phantom signal intensities in nonuniformity corrected STIR-MRI examinations of skeletal muscle.
Magma (New York, N.Y.) 2009;22(4):201-9.
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2009: Olthof Allard W; Sijens Paul E; Kreeftenberg Herman G; Kappert Peter; van der Jagt Eric J; Oudkerk Matthijs
Non-invasive liver iron concentration measurement by MRI: comparison of two validated protocols.
European journal of radiology 2009;71(1):116-21.
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2009: Dikkers R; Greuter M J W; Kristanto W; van Ooijen P M A; Sijens P E; Willems T P; Oudkerk M
Assessment of image quality of 64-row Dual Source versus Single Source CT coronary angiography on heart rate: a phantom study.
European journal of radiology 2009;70(1):61-8.
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2009: Verbruggen Krijn T; Meiners Linda C; Sijens Paul E; Lunsing Roelineke J; van Spronsen Francjan J; Brouwer Oebele F
Magnetic resonance imaging and proton magnetic resonance spectroscopy of the brain in the diagnostic evaluation of developmental delay.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 2009;13(2):181-90.
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2008: Sijens Paul E; Mostert Jop P; Irwan Roy; Potze Jan Hendrik; Oudkerk Matthijs; De Keyser Jacques
Impact of fluoxetine on the human brain in multiple sclerosis as quantified by proton magnetic resonance spectroscopy and diffusion tensor imaging.
Psychiatry research 2008;164(3):274-82.
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2008: Sijens Paul E; Alkefaji Heyder; Lunsing Roelineke J; van Spronsen Francjan J; Meiners Linda C; Oudkerk Matthijs; Verkade Henkjan J
Quantitative multivoxel 1H MR spectroscopy of the brain in children with acute liver failure.
European radiology 2008;18(11):2601-9.
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2008: Borra Ronald; Lautamäki Riika; Parkkola Riita; Komu Markku; Sijens Paul E; Hällsten Kirsti; Bergman Jörgen; Iozzo Patricia; Nuutila Pirjo
Inverse association between liver fat content and hepatic glucose uptake in patients with type 2 diabetes mellitus.
Metabolism: clinical and experimental 2008;57(10):1445-51.
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2008: Sijens P E; Smit G P A; Rödiger L A; van Spronsen F J; Oudkerk M; Rodenburg R J; Lunsing R J
MR spectroscopy of the brain in Leigh syndrome.
Brain & development 2008;30(9):579-83.
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2008: Irwan Roy; de Vries Henk B K; Sijens Paul E
The impact of scan length on the exposure levels in 16- and 64-row multidetector computed tomography: a phantom study.
Academic radiology 2008;15(9):1142-7.
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2008: Sijens Paul E; Rödiger Lars A; Meiners Linda C; Lunsing Roelineke J
1H magnetic resonance spectroscopy in monocarboxylate transporter 8 gene deficiency.
The Journal of clinical endocrinology and metabolism 2008;93(5):1854-9.
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2008: Irwan Roy; Edens Mireille A; Sijens Paul E
Assessment of the variations in fat content in normal liver using a fast MR imaging method in comparison with results obtained by spectroscopic imaging.
European radiology 2008;18(4):806-13.
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2008: Sijens Paul E; Oudkerk Matthijs
Letter to the editor re: Richard J. Maddock et al. "Brain lactate responses during visual stimulation in fasting and hyperglycemic subjects: a proton magnetic resonance study at 1.5 T" [Psychiatry Research 2006; 148:47-54].
Psychiatry research 2008;162(2):173-4; author reply 175-9.
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2007: Sijens P E; Heesters M A A M; Enting R H; van der Graaf W T A; Potze J H; Irwan R; Meiners L C; Oudkerk M
Diffusion tensor imaging and chemical shift imaging assessment of heterogeneity in low grade glioma under temozolomide chemotherapy.
Cancer investigation 2007;25(8):706-10.
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2007: van Oostrom Joost C H; Sijens Paul E; Roos Raymund A C; Leenders Klaus L
1H magnetic resonance spectroscopy in preclinical Huntington disease.
Brain research 2007;1168():67-71.
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2007: Verbruggen Krijn T; Knijff Wilma A; Soorani-Lunsing Roelineke J; Sijens Paul E; Verhoeven Nanda M; Salomons Gajja S; Goorhuis-Brouwer Siena M; van Spronsen Francjan J
Global developmental delay in guanidionacetate methyltransferase deficiency: differences in formal testing and clinical observation.
European journal of pediatrics 2007;166(9):921-5.
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2007: Verbruggen Krijn T; Sijens Paul E; Schulze Andreas; Lunsing Roelineke J; Jakobs Cornelis; Salomons Gajja S; van Spronsen Francjan J
Successful treatment of a guanidinoacetate methyltransferase deficient patient: findings with relevance to treatment strategy and pathophysiology.
Molecular genetics and metabolism 2007;91(3):294-6.
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2007: Irwan Roy; Lubbers Daniël D; van der Vleuten Pieter A; Kappert Peter; Götte Marco J W; Sijens Paul E
Parallel imaging for first-pass myocardial perfusion.
Magnetic resonance imaging 2007;25(5):678-83.
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2007: Sijens P E; Fock J M; Meiners L C; Potze J H; Irwan R; Oudkerk M
MR spectroscopy and diffusion tensor imaging of the brain in congenital muscular dystrophy with merosin deficiency: metabolite level decreases, fractional anisotropy decreases, and apparent diffusion coefficient increases in the white matter.
Brain & development 2007;29(5):317-21.
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2007: Olthof Allard W; Sijens Paul E; Kreeftenberg Herman G; Kappert Peter; Irwan Roy; van der Jagt Eric J; Oudkerk Matthijs
Correlation between serum ferritin levels and liver iron concentration determined by MR imaging: impact of hematologic disease and inflammation.
Magnetic resonance imaging 2007;25(2):228-31.
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2006: Sijens Paul E; Smit G Peter; Borgdorff Marinus A J; Kappert Peter; Oudkerk Matthijs
Multiple voxel 1H MR spectroscopy of phosphorylase-b kinase deficient patients (GSD IXa) showing an accumulation of fat in the liver that resolves with aging.
Journal of hepatology 2006;45(6):851-5.
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2006: Sijens P E; Gieteling E W; Meiners L C; Sival D A; Potze J H; Irwan R; Oudkerk M
Diffusion tensor imaging and magnetic resonance spectroscopy of the brain in a patient with Sturge-Weber syndrome.
Acta radiologica (Stockholm, Sweden : 1987) 2006;47(9):972-6.
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2006: van Spronsen F J; Reijngoud D J; Verhoeven N M; Soorani-Lunsing R J; Jakobs C; Sijens P E
High cerebral guanidinoacetate and variable creatine concentrations in argininosuccinate synthetase and lyase deficiency: implications for treatment?
Molecular genetics and metabolism 2006;89(3):274-6.
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2006: Irwan Roy; Rüssel Iris K; Sijens Paul E
Fast 3D coronary artery contrast-enhanced magnetic resonance angiography with magnetization transfer contrast, fat suppression and parallel imaging as applied on an anthropomorphic moving heart phantom.
Magnetic resonance imaging 2006;24(7):895-902.
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2006: Mostert Jop P; Sijens Paul E; Oudkerk Matthijs; De Keyser Jacques
Fluoxetine increases cerebral white matter NAA/Cr ratio in patients with multiple sclerosis.
Neuroscience letters 2006;402(1-2):22-4.
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2006: Sijens P E; Smit G P A; Meiners L C; Oudkerk M; van Spronsen F J
Cerebral 1H MR spectroscopy revealing white matter NAA decreases in glutaric aciduria type I.
Molecular genetics and metabolism 2006;88(3):285-9.
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2006: Sijens P E; Reijngoud D-J; Soorani-Lunsing R J; Oudkerk M; van Spronsen F J
Cerebral 1H MR spectroscopy showing elevation of brain guanidinoacetate in argininosuccinate lyase deficiency.
Molecular genetics and metabolism 2006;88(1):100-2.
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2006: Sijens Paul E; Irwan Roy; Potze Jan Hendrik; Mostert Jop P; De Keyser Jacques; Oudkerk Matthijs
Relationships between brain water content and diffusion tensor imaging parameters (apparent diffusion coefficient and fractional anisotropy) in multiple sclerosis.
European radiology 2006;16(4):898-904.
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2006: den Heijer T; Sijens P E; Prins N D; Hofman A; Koudstaal P J; Oudkerk M; Breteler M M B
MR spectroscopy of brain white matter in the prediction of dementia.
Neurology 2006;66(4):540-4.
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2006: Sijens Paul E; Mostert Jop P; Oudkerk Matthijs; De Keyser Jacques
(1)H MR spectroscopy of the brain in multiple sclerosis subtypes with analysis of the metabolite concentrations in gray and white matter: initial findings.
European radiology 2006;16(2):489-95.
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2005: Sijens P E; Verbruggen K T; Oudkerk M; van Spronsen F J; Soorani-Lunsing R J
1H MR spectroscopy of the brain in Cr transporter defect.
Molecular genetics and metabolism 2005;86(3):421-2.
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2005: Sijens Paul E; Boon Maartje; Meiners Linda C; Brouwer Oebele F; Oudkerk Matthijs
1H chemical shift imaging, MRI, and diffusion-weighted imaging in vanishing white matter disease.
European radiology 2005;15(11):2377-9.
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2005: Irwan Roy; Sijens Paul E; Potze Jan-Hendrik; Oudkerk Matthijs
Correlation of proton MR spectroscopy and diffusion tensor imaging.
Magnetic resonance imaging 2005;23(8):851-8.
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2005: Sijens P E; Verbruggen K T; Meiners L C; Soorani-Lunsing R J; Rake J P; Oudkerk M
1H chemical shift imaging of the brain in guanidino methyltransferase deficiency, a creatine deficiency syndrome; guanidinoacetate accumulation in the gray matter.
European radiology 2005;15(9):1923-6.
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2005: Oudesluijs Grétel G; Hordijk Roel; Boon Maartje; Sijens Paul E; Hennekam Raoul C M
Plantar lipomatosis, unusual facies, and developmental delay: confirmation of Pierpont syndrome.
American journal of medical genetics. Part A 2005;137(1):77-80.
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2005: Sijens Paul E; Irwan Roy; Potze Jan Hendrik; Mostert Jop P; De Keyser Jacques; Oudkerk Matthijs
Analysis of the human brain in primary progressive multiple sclerosis with mapping of the spatial distributions using 1H MR spectroscopy and diffusion tensor imaging.
European radiology 2005;15(8):1686-93.
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2005: Mostert Jop P; Sijens Paul E; Oudkerk Matthijs; De Keyser Jacques
1H Magnetic resonance spectroscopy of the internal capsule in human brain: a feasibility study to detect lactate following contralateral motor activity.
European radiology 2005;15(7):1349-52.
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2005: Boucard Christine C; Mostert Jop P; Cornelissen Frans W; De Keyser Jacques; Oudkerk Matthijs; Sijens Paul E
Visual stimulation, 1H MR spectroscopy and fMRI of the human visual pathways.
European radiology 2005;15(1):47-52.
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2004: Sijens Paul E; Oudkerk Matthijs; Reijngoud Dirk-Jan; Leenders Klaas L; de Valk Harold W; van Spronsen Francjan J
1H MR chemical shift imaging detection of phenylalanine in patients suffering from phenylketonuria (PKU).
European radiology 2004;14(10):1895-900.
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2003: Sijens Paul E; den Heijer Tom; Origgi Daniela; Vermeer Sarah E; Breteler Monique M B; Hofman Albert; Oudkerk Matthijs
Brain changes with aging: MR spectroscopy at supraventricular plane shows differences between women and men.
Radiology 2003;226(3):889-96.
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2002: Sijens Paul E; Oudkerk Matthijs
1H chemical shift imaging characterization of human brain tumor and edema.
European radiology 2002;12(8):2056-61.
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2002: Sijens Paul E; Oudkerk Matthijs
Should patients be managed for suspected pulmonary embolism on the basis of pretest clinical probability and D-dimer results?
Annals of internal medicine 2002;136(10):781.
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2002: Sijens P E; Oudkerk M
Diagnosing dural metastases.
Neuroradiology 2002;44(3):275; author reply 276.
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2002: Leij-Halfwerk Susanne; Agteresch Hendrik J; Sijens Paul E; Dagnelie Pieter C
Adenosine triphosphate infusion increases liver energy status in advanced lung cancer patients: an in vivo 31P magnetic resonance spectroscopy study.
Hepatology (Baltimore, Md.) 2002;35(2):421-4.
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2001: Sijens P E; Oudkerk M; Berghout A; van Ingen H E; Kemperman H
Comparison of a quantitative latex and a quantitative ELISA plasma D-dimer assay in the exclusion of segmental and subsegmental pulmonary embolism.
Thrombosis and haemostasis 2001;86(6):1580-2.
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2001: Sijens P E; Den Heijer T; De Leeuw F E; De Groot J C; Achten E; Heijboer R J; Hofman A; Breteler M M; Oudkerk M
Human brain chemical shift imaging at age 60 to 90: analysis of the causes of the observed sex differences in brain metabolites.
Investigative radiology 2001;36(10):597-603.
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2001: Sijens P E; den Heijer T; de Leeuw F E; de Groot J C; Achten E; Heijboer R J; Hofman A; Breteler M M; Oudkerk M
MR spectroscopy detection of lactate and lipid signals in the brains of healthy elderly people.
European radiology 2001;11(8):1495-501.
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2001: Sijens P E; Oudkerk M
Exclusion of pulmonary embolism using quantitative plasma D-dimer assays.
Clinical laboratory 2001;47(7-8):321-6.
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2000: Sijens P E; van Ingen H E; van Beek E J; Berghout A; Oudkerk M
Rapid ELISA assay for plasma D-dimer in the diagnosis of segmental and subsegmental pulmonary embolism. A comparison with pulmonary angiography.
Thrombosis and haemostasis 2000;84(2):156-9.
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2000: Leij-Halfwerk S; Dagneli P C; Kappert P; Oudkerk M; Sijens P E
Decreased energy and phosphorylation status in the liver of lung cancer patients with weight loss.
Journal of hepatology 2000;32(6):887-92.
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2000: Leij-Halfwerk S; van den Berg J W; Sijens P E; Wilson J H; Oudkerk M; Dagnelie P C
Altered hepatic gluconeogenesis during L-alanine infusion in weight-losing lung cancer patients as observed by phosphorus magnetic resonance spectroscopy and turnover measurements.
Cancer research 2000;60(3):618-23.
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2000: Leij-Halfwerk S; Dagnelie P C; Van Den Berg J W; Wilson J H; Sijens P E
Hepatic sugar phosphate levels reflect gluconeogenesis in lung cancer: simultaneous turnover measurements and 31P magnetic resonance spectroscopy in vivo.
Clinical science (London, England : 1979) 2000;98(2):167-74.
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1999: Dagnelie P C; Sijens P E; Kraus D J; Planting A S; van Dijk P v
Abnormal liver metabolism in cancer patients detected by (31)P MR spectroscopy.
NMR in biomedicine 1999;12(8):535-44.
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1999: Sijens P E; Oudkerk M; de Leeuw F E; de Groot J C; Achten E; Heijboer R; Hofman A; Breteler M M
1H chemical shift imaging of the human brain at age 60-90 years reveals metabolic differences between women and men.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1999;42(1):24-31.
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1998: Sijens P E; Oudkerk M; van Dijk P; Levendag P C; Vecht C J
1H MR spectroscopy monitoring of changes in choline peak area and line shape after Gd-contrast administration.
Magnetic resonance imaging 1998;16(10):1273-80.
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1998: Sijens P E
Phosphorus MR spectroscopy in the treatment of human extremity sarcomas.
NMR in biomedicine 1998;11(7):341-53.
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1998: Sijens P E; Dagnelie P C; Halfwerk S; van Dijk P; Wicklow K; Oudkerk M
Understanding the discrepancies between 31P MR spectroscopy assessed liver metabolite concentrations from different institutions.
Magnetic resonance imaging 1998;16(2):205-11.
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1997: Sijens P E; van den Bent M J; Oudkerk M
Phosphorus-31 chemical shift imaging of metastatic tumors located in the spine region.
Investigative radiology 1997;32(6):344-50.
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1997: Sijens P E; van den Bent M J; Nowak P J; van Dijk P; Oudkerk M
1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;37(2):222-5.
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1997: Sijens P E; Baldwin N J; Ng T C
31P magnetic resonance spectroscopy detection of response-predictive adenosine triphosphate decrease in irradiated radiation-induced fibrosarcoma-1 tumors.
Investigative radiology 1997;32(1):39-43.
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1997: Van Dijk P; Sijens P E; Schmitz P I; Oudkerk M
Gd-enhanced MR imaging of brain metastases: contrast as a function of dose and lesion size.
Magnetic resonance imaging 1997;15(5):535-41.
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1996: Sijens P E; Levendag P C; Vecht C J; van Dijk P; Oudkerk M
1H MR spectroscopy detection of lipids and lactate in metastatic brain tumors.
NMR in biomedicine 1996;9(2):65-71.
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1995: Sijens P E; Vecht C J; Levendag P C; van Dijk P; Oudkerk M
Hydrogen magnetic resonance spectroscopy follow-up after radiation therapy of human brain cancer. Unexpected inverse correlation between the changes in tumor choline level and post-gadolinium magnetic resonance imaging contrast.
Investigative radiology 1995;30(12):738-44.
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1995: Sijens P E; Eggermont A M; van Dijk P V; Oudkerk M
31P magnetic resonance spectroscopy as predictor of clinical response in human extremity sarcomas treated by single dose TNF-alpha + melphalan isolated limb perfusion.
NMR in biomedicine 1995;8(5):215-24.
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1995: Sijens P E; Knopp M V; Brunetti A; Wicklow K; Alfano B; Bachert P; Sanders J A; Stillman A E; Kett H; Sauter R
1H MR spectroscopy in patients with metastatic brain tumors: a multicenter study.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1995;33(6):818-26.
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1995: Oudkerk M; Sijens P E; Van Beek E J; Kuijpers T J
Safety and efficacy of dotarem (Gd-DOTA) versus magnevist (Gd-DTPA) in magnetic resonance imaging of the central nervous system.
Investigative radiology 1995;30(2):75-8.
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1995: Sijens P E
31P (MRS) changes as a measure of therapy response in human osteosarcomas implanted into nude mice.
Magnetic resonance imaging 1995;13(3):495-6.
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1995: Sijens P E; Van Dijk P; Dagnelie P C; Oudkerk M
Non-T1-weighted 31P chemical shift imaging of the human liver.
Magnetic resonance imaging 1995;13(4):621-8.
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1994: Sijens P E; van Dijk P; Oudkerk M
Correlation between choline level and Gd-DTPA enhancement in patients with brain metastases of mammary carcinoma.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1994;32(5):549-55.
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1992: Sijens P E; Ng T C
Thymidine-modulated 5-fluorouracil metabolism in liver and RIF-1 tumors studied by 19F magnetic resonance spectroscopy.
Magnetic resonance imaging 1992;10(3):385-92.
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1991: Sijens P E; Baldwin N J; Ng T C
Multinuclear MR investigation of the metabolic response of the murine RIF-1 tumor to 5-fluorouracil chemotherapy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1991;19(2):373-85.
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1991: Sijens P E; Stoter G; Oudkerk M
[Magnetic resonance spectroscopy; current possibilities for the staging of tumors and the evaluation of response to therapy]
Nederlands tijdschrift voor geneeskunde 1991;135(9):361-6.
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1991: Sijens P E; Huang Y M; Baldwin N J; Ng T C
19F magnetic resonance spectroscopy studies of the metabolism of 5-fluorouracil in murine RIF-1 tumors and liver.
Cancer research 1991;51(5):1384-90.
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1990: Sijens P E; van Echteld C J; van Rijssel R H; Lagendijk J J; Neijt J P; de Jong W H; van der Minnen A C; de Groot G; Seijkens D
31P NMR study of cisplatin- and doxorubicin-induced changes in tumour metabolism in rats with a cisplatin-sensitive or -resistant immunocytoma.
NMR in biomedicine 1990;3(3):124-31.
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1990: Scheiber C; Kiss R; De Launoit Y; Sijens P; Frühling J
Influence of hormono- and/or chemotherapy on the MXT mouse mammary tumor as monitored by 31P MRS.
European journal of cancer (Oxford, England : 1990) 1990;26(3):241-51.
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1989: Sijens P E; van Echteld C J; Neijt J P; Schipper J; Dunki Jacobs P B; de Graaf P W; Seijkens D
31P NMR study of the impact of dietary manipulation on tumor metabolism and response to methotrexate.
NMR in biomedicine 1989;2(1):12-8.
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1989: Sijens P E; Bovee W M; Koole P; Schipper J
Phosphorus NMR study of the response of a murine tumour to hyperthermia as a function of treatment time and temperature.
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 1989;5(3):351-7.
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1988: Sijens P E; Wijrdeman H K; Moerland M A; Bakker C J; Vermeulen J W; Luyten P R
Human breast cancer in vivo: H-1 and P-31 MR spectroscopy at 1.5 T.
Radiology 1988;169(3):615-20.
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1988: Sijens P E; Bovee W M
In vivo 31P nuclear magnetic resonance spectroscopy of subcutaneous 9L gliosarcoma: effects of tumor growth and treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea on tumor bioenergetics and histology.
Cancer research 1988;48(19):5610-1.
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1987: Sijens P E; Bovée W M; Seijkens D; Koole P; Los G; van Rijssel R H
Murine mammary tumor response to hyperthermia and radiotherapy evaluated by in vivo 31P-nuclear magnetic resonance spectroscopy.
Cancer research 1987;47(24 Pt 1):6467-73.
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1986: Sijens P E; Bovée W M; Seijkens D; Los G; Rutgers D H
In vivo 31P-nuclear magnetic resonance study of the response of a murine mammary tumor to different doses of gamma-radiation.
Cancer research 1986;46(3):1427-32.
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