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Agueda Rostagno

Research Profile

Chemicals & Drugs

Disorders

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Publications

TOP 3
S Fossati; J Ghiso; Agueda Rostagno
TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ.
Miguel Calero; Agueda Rostagno; Jorge Ghiso
Search for amyloid-binding proteins by affinity chromatography.
Silvia Fossati; Jorge Ghiso; Agueda Rostagno
Insights into caspase-mediated apoptotic pathways induced by amyloid-β in cerebral microvascular endothelial cells.

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All Publications

2012: S Fossati; J Ghiso; Agueda Rostagno
TRAIL death receptors DR4 and DR5 mediate cerebral microvascular endothelial cell apoptosis induced by oligomeric Alzheimer's Aβ.
Cell death & disease 2012;3():e321.
2012: Miguel Calero; Agueda Rostagno; Jorge Ghiso
Search for amyloid-binding proteins by affinity chromatography.
Methods in molecular biology (Clifton, N.J.) 2012;849():213-23.
2012: Silvia Fossati; Jorge Ghiso; Agueda Rostagno
Insights into caspase-mediated apoptotic pathways induced by amyloid-β in cerebral microvascular endothelial cells.
Neuro-degenerative diseases 2012;10(1-4):324-8.
2010: Yasushi Tomidokoro; Agueda Rostagno; Thomas A Neubert; Yun Lu; G William Rebeck; Blas Frangione; Steven M Greenberg; Jorge Ghiso
Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits.
The American journal of pathology 2010;176(4):1841-54.
2010: Agueda Rostagno; J L Holton; Tammaryn Lashley; Tamas Revesz; Jorge Ghiso
Cerebral amyloidosis: amyloid subunits, mutants and phenotypes.
Cellular and molecular life sciences : CMLS 2010;67(4):581-600.
2010: S Fossati; J Cam; J Meyerson; E Mezhericher; Ignacio Romero; P O Couraud; B B Weksler; Jorge Ghiso; Agueda Rostagno
Differential activation of mitochondrial apoptotic pathways by vasculotropic amyloid-beta variants in cells composing the cerebral vessel walls.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(1):229-41.
2010: Maria Tsachaki; Jorge Ghiso; Agueda Rostagno; Spiros Efthimiopoulos
BRI2 homodimerizes with the involvement of intermolecular disulfide bonds.
Neurobiology of aging 2010;31(1):88-98.
2009: Agueda Rostagno; Jorge Ghiso
Isolation and biochemical characterization of amyloid plaques and paired helical filaments.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2009;Chapter 3():Unit 3.33 3.33.1-33.
2009: Tamas Revesz; Janice L Holton; Tammaryn Lashley; Gordon Plant; Blas Frangione; Agueda Rostagno; Jorge Ghiso
Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.
Acta neuropathologica 2009;118(1):115-30.
2009: R J S Viana; A F Nunes; Rui E Castro; Rita M Ramalho; J Meyerson; S Fossati; Jorge Ghiso; Agueda Rostagno; Cecília M P Rodrigues
Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells.
Cellular and molecular life sciences : CMLS 2009;66(6):1094-104.
2009: Raffaella Solito; Federico Corti; Silvia Fossati; Emiliya Mezhericher; Sandra Donnini; Jorge Ghiso; Antonio Giachetti; Agueda Rostagno; Marina Ziche
Dutch and Arctic mutant peptides of beta amyloid(1-40) differentially affect the FGF-2 pathway in brain endothelium.
Experimental cell research 2009;315(3):385-95.
2008: Tammaryn Lashley; Tamas Revesz; Gordon Plant; R Bandopadhyay; Andrew J Lees; Blas Frangione; Nicholas W Wood; Rohan de Silva; Jorge Ghiso; Agueda Rostagno; Janice L Holton
Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.
Neuropathology and applied neurobiology 2008;34(5):492-505.
2008: Agueda Rostagno; Jorge Ghiso
Preamyloid lesions and cerebrovascular deposits in the mechanism of dementia: lessons from non-beta-amyloid cerebral amyloidosis.
Neuro-degenerative diseases 2008;5(3-4):173-5.
2007: Agueda Rostagno; Tammaryn Lashley; Douglas Ng; Jordana Meyerson; Hans Braendgaard; Gordon Plant; Marie Bojsen-Møller; Janice Holton; Blas Frangione; Tamas Revesz; Jorge Ghiso
Preferential association of serum amyloid P component with fibrillar deposits in familial British and Danish dementias: similarities with Alzheimer's disease.
Journal of the neurological sciences 2007;257(1-2):88-96.
2007: Boris Ovodenko; Agueda Rostagno; Thomas A Neubert; Vivekananda Shetty; Stefani N Thomas; Austin Yang; Jeffrey M Liebmann; Jorge Ghiso; Robert Ritch
Proteomic analysis of exfoliation deposits.
Investigative ophthalmology & visual science 2007;48(4):1447-57.
2006: Tammaryn Lashley; Janice L Holton; Marcel M Verbeek; Agueda Rostagno; Marie Bojsen-Møller; Guido David; Jack van Horssen; Hans Braendgaard; Gordon Plant; Blas Frangione; Jorge Ghiso; Tamas Revesz
Molecular chaperons, amyloid and preamyloid lesions in the BRI2 gene-related dementias: a morphological study.
Neuropathology and applied neurobiology 2006;32(5):492-504.
2006: Jorge Ghiso; Agueda Rostagno; Yasushi Tomidokoro; Tammaryn Lashley; Marie Bojsen-Møller; Hans Braendgaard; Gordon Plant; Janice Holton; Ratneshwar Lal; Tamas Revesz; Blas Frangione
Genetic alterations of the BRI2 gene: familial British and Danish dementias.
Brain pathology (Zurich, Switzerland) 2006;16(1):71-9.
2005: Yasushi Tomidokoro; Tammaryn Lashley; Agueda Rostagno; Thomas A Neubert; Marie Bojsen-Møller; Hans Braendgaard; Gordon Plant; Janice Holton; Blas Frangione; Tamas Révész; Jorge Ghiso
Familial Danish dementia: co-existence of Danish and Alzheimer amyloid subunits (ADan AND A{beta}) in the absence of compact plaques.
The Journal of biological chemistry 2005;280(44):36883-94.
2005: Angeliki Fotinopoulou; Maria Tsachaki; Maria Vlavaki; Alexandros Poulopoulos; Agueda Rostagno; Blas Frangione; Jorge Ghiso; Spiros Efthimiopoulos
BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production.
The Journal of biological chemistry 2005;280(35):30768-72.
2005: Agueda Rostagno; Yasushi Tomidokoro; Tammaryn Lashley; Douglas Ng; Gordon Plant; Janice Holton; Blas Frangione; Tamas Revesz; Jorge Ghiso
Chromosome 13 dementias.
Cellular and molecular life sciences : CMLS 2005;62(16):1814-25.
2005: Miguel Calero; Agueda Rostagno; Blas Frangione; Jorge Ghiso
Clusterin and Alzheimer's disease.
Sub-cellular biochemistry 2005;38():273-98.
2004: Jorge Ghiso; Marcos Shayo; Miguel Calero; Douglas Ng; Yasushi Tomidokoro; Sam Gandy; Agueda Rostagno; Blas Frangione
Systemic catabolism of Alzheimer's Abeta40 and Abeta42.
The Journal of biological chemistry 2004;279(44):45897-908.
2003: Tamas Revesz; Jorge Ghiso; Tammaryn Lashley; Gordon Plant; Agueda Rostagno; Blas Frangione; Janice L Holton
Cerebral amyloid angiopathies: a pathologic, biochemical, and genetic view.
Journal of neuropathology and experimental neurology 2003;62(9):885-98.
2002: Agueda Rostagno; Tamas Revesz; Tammaryn Lashley; Yasushi Tomidokoro; Laura Magnotti; Hans Braendgaard; Gordon Plant; Marie Bojsen-Møller; Janice Holton; Blas Frangione; Jorge Ghiso
Complement activation in chromosome 13 dementias. Similarities with Alzheimer's disease.
The Journal of biological chemistry 2002;277(51):49782-90.
2002: Agueda Rostagno; Glauco Frizzera; Lourdes R Ylagan; Asok Kumar; Jorge Ghiso; Gloria Gallo
Tumoral non-amyloidotic monoclonal immunoglobulin light chain deposits ('aggregoma'): presenting feature of B-cell dyscrasia in three cases with immunohistochemical and biochemical analyses.
British journal of haematology 2002;119(1):62-9.
2002: Tamas Revesz; Janice L Holton; Tammaryn Lashley; Gordon Plant; Agueda Rostagno; Jorge Ghiso; Blas Frangione
Sporadic and familial cerebral amyloid angiopathies.
Brain pathology (Zurich, Switzerland) 2002;12(3):343-57.
2002: Agueda Rostagno; Gloria Gallo; Leslie I Gold
Binding of polymeric IgG to fibronectin in extracellular matrices: an in vitro paradigm for immune-complex deposition.
Molecular immunology 2002;38(15):1101-11.
2002: Janice L Holton; Tammaryn Lashley; Jorge Ghiso; Hans Braendgaard; Ruben Vidal; Christopher J Guerin; Graham Gibb; Diane P Hanger; Agueda Rostagno; Brian H Anderton; Catherine Strand; Hilary Ayling; Gordon Plant; Blas Frangione; Marie Bojsen-Møller; Tamas Revesz
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.
Journal of neuropathology and experimental neurology 2002;61(3):254-67.
2001: Jorge Ghiso; Tamas Révész; Janice Holton; Agueda Rostagno; Tammaryn Lashley; Henry Houlden; Graham Gibb; Brian H Anderton; T Bek; Marie Bojsen-Møller; Nicholas W Wood; Ruben Vidal; Hans Braendgaard; Gordon Plant; Blas Frangione
Chromosome 13 dementia syndromes as models of neurodegeneration.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8(4):277-84.
2001: Jorge Ghiso; Janice Holton; Leticia Miravalle; Miguel Calero; Tammaryn Lashley; Ruben Vidal; Henry Houlden; Nicholas W Wood; Thomas A Neubert; Agueda Rostagno; Gordon Plant; Tamas Revesz; Blas Frangione
Systemic amyloid deposits in familial British dementia.
The Journal of biological chemistry 2001;276(47):43909-14.
2001: Blas Frangione; Tamas Révész; Ruben Vidal; Janice Holton; Tammaryn Lashley; Henry Houlden; Nicholas W Wood; Agueda Rostagno; Gordon Plant; Jorge Ghiso
Familial cerebral amyloid angiopathy related to stroke and dementia.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2001;8 Suppl 1():36-42.
2001: Janice L Holton; Jorge Ghiso; Tammaryn Lashley; Agueda Rostagno; C J Guerin; Graham Gibb; Henry Houlden; H Ayling; Lillian Martinian; Brian H Anderton; Nicholas W Wood; Ruben Vidal; Gordon Plant; Blas Frangione; Tamas Revesz
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia.
The American journal of pathology 2001;158(2):515-26.
2000: Miguel Calero; Agueda Rostagno; E Matsubara; Berislav V Zlokovic; Blas Frangione; Jorge Ghiso
Apolipoprotein J (clusterin) and Alzheimer's disease.
Microscopy research and technique 2000;50(4):305-15.
2000: T Tokuda; Miguel Calero; E Matsubara; Ruben Vidal; Asok Kumar; Bruno Permanne; Berislav V Zlokovic; Jonathan D. Smith; Mary Jo Ladu; Agueda Rostagno; Blas Frangione; Jorge Ghiso
Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid beta peptides.
The Biochemical journal 2000;348 Pt 2():359-65.
2000: J Liu; G Prolla; Agueda Rostagno; Roberto Chiarle; Helen Feiner; Giorgio Inghirami
Initiation of translation from a downstream in-frame AUG codon on BRCA1 can generate the novel isoform protein DeltaBRCA1(17aa).
Oncogene 2000;19(23):2767-73.
2000: Ruben Vidal; Tamas Revesz; Agueda Rostagno; E Kim; J L Holton; T Bek; Marie Bojsen-Møller; Hans Braendgaard; Gordon Plant; Jorge Ghiso; Blas Frangione
A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4920-5.
2000: Jorge Ghiso; Ruben Vidal; Agueda Rostagno; simon mead; Tamas Révész; Gordon Plant; Blas Frangione
A newly formed amyloidogenic fragment due to a stop codon mutation causes familial British dementia.
Annals of the New York Academy of Sciences 2000;903():129-37.
2000: Jorge Ghiso; Ruben Vidal; Agueda Rostagno; Leticia Miravalle; J L Holton; simon mead; Tamas Révész; Gordon Plant; Blas Frangione
Amyloidogenesis in familial British dementia is associated with a genetic defect on chromosome 13.
Annals of the New York Academy of Sciences 2000;920():84-92.
2000: Blas Frangione; Ruben Vidal; Agueda Rostagno; Jorge Ghiso
Familial cerebral amyloid angiopathies and dementia.
Alzheimer disease and associated disorders 2000;14 Suppl 1():S25-30.
1999: Agueda Rostagno; Ruben Vidal; B Kaplan; J Chuba; Asok Kumar; J I Elliott; Blas Frangione; Gloria Gallo; Jorge Ghiso
pH-dependent fibrillogenesis of a VkappaIII Bence Jones protein.
British journal of haematology 1999;107(4):835-43.
1999: Miguel Calero; T Tokuda; Agueda Rostagno; Asok Kumar; Berislav V Zlokovic; Blas Frangione; Jorge Ghiso
Functional and structural properties of lipid-associated apolipoprotein J (clusterin).
The Biochemical journal 1999;344 Pt 2():375-83.
1999: Ruben Vidal; Blas Frangione; Agueda Rostagno; simon mead; Tamas Révész; Gordon Plant; Jorge Ghiso
A stop-codon mutation in the BRI gene associated with familial British dementia.
Nature 1999;399(6738):776-81.
1999: Agueda Rostagno; J E Schwarzbauer; Leslie I Gold
Comparison of the fibrin-binding activities in the N- and C-termini of fibronectin.
The Biochemical journal 1999;338 ( Pt 2)():375-86.
1998: Marco Pizzolato; G Bragantini; P Bresciani; Santiago Pavlovsky; J Chuba; Ruben Vidal; Agueda Rostagno; Jorge Ghiso
IgG1-kappa biclonal gammopathy associated with multiple myeloma suggests a regulatory mechanism.
British journal of haematology 1998;102(2):503-8.
1996: Agueda Rostagno; Ruben Vidal; Asok Kumar; J Chuba; G Niederman; L Gold; Blas Frangione; Jorge Ghiso; Gloria Gallo
Fibrillary glomerulonephritis related to serum fibrillar immunoglobulin-fibronectin complexes.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1996;28(5):676-84.
1996: Agueda Rostagno; M Williams; Blas Frangione; Leslie I Gold
Biochemical analysis of the interaction of fibronectin with IgG and localization of the respective binding sites.
Molecular immunology 1996;33(6):561-72.
1994: Agueda Rostagno; M J Williams; M Baron; Iain D Campbell; Leslie I Gold
Further characterization of the NH2-terminal fibrin-binding site on fibronectin.
The Journal of biological chemistry 1994;269(50):31938-45.
1994: M J Williams; I Phan; T S Harvey; Agueda Rostagno; Leslie I Gold; Iain D Campbell
Solution structure of a pair of fibronectin type 1 modules with fibrin binding activity.
Journal of molecular biology 1994;235(4):1302-11.
1992: Jorge Ghiso; Agueda Rostagno; J E Gardella; L Liem; P D Gorevic; Blas Frangione
A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion.
The Biochemical journal 1992;288 ( Pt 3)():1053-9.
1992: Leslie I Gold; Agueda Rostagno; Blas Frangione; T Passalaris
Localization of the cleavage sites on fibronectin following digestion by urokinase.
Journal of cellular biochemistry 1992;50(4):441-52.
1992: Jorge Ghiso; Thomas Wisniewski; Ruben Vidal; Agueda Rostagno; Blas Frangione
Epitope map of two polyclonal antibodies that recognize amyloid lesions in patients with Alzheimer's disease.
The Biochemical journal 1992;282 ( Pt 2)():517-22.
1991: Agueda Rostagno; Blas Frangione; L Gold
Biochemical studies on the interaction of fibronectin with Ig.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(8):2687-93.
1990: Jorge Ghiso; E Saball; J Leoni; Agueda Rostagno; Blas Frangione
Binding of cystatin C to C4: the importance of sense-antisense peptides in their interaction.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(4):1288-91.
1989: Agueda Rostagno; Blas Frangione; Leslie I Gold
Biochemical characterization of the fibronectin binding sites for IgG.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(10):3277-82.
1989: M Salvarrey; Agueda Rostagno
Affinity of fibronectin for polyclonal IgG.
Clinical and experimental immunology 1989;76(1):92-6.
1987: Angeles Garcia-Pardo; Agueda Rostagno; Blas Frangione
Primary structure of human plasma fibronectin. Characterization of a 38 kDa domain containing the C-terminal heparin-binding site (Hep III site) and a region of molecular heterogeneity.
The Biochemical journal 1987;241(3):923-8.
1986: Agueda Rostagno; Blas Frangione; E Pearlstein; Angeles Garcia-Pardo
Fibronectin binds to amyloid P component. Localization of the binding site to the 31,000 dalton C-terminal domain.
Biochemical and biophysical research communications 1986;140(1):12-20.