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Terrence Town

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Juan Carlos Biancotti; Terrence Town
Increasing hematopoietic stem cell yield to develop mice with human immune systems.
Takashi Mori; Jun Tan; Marie-Victoire Guillot-Sestier; Naoki Koyama; Terrence Town
Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.
David Gate; Rachelle Levy; Joshua J Breunig; Moise Danielpour; Terrence Town
Basic biology and mechanisms of neural ciliogenesis and the B9 family.

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All Publications

2013: Juan Carlos Biancotti; Terrence Town
Increasing hematopoietic stem cell yield to develop mice with human immune systems.
BioMed research international 2013;2013():740892.
2013: Takashi Mori; Jun Tan; Marie-Victoire Guillot-Sestier; Naoki Koyama; Terrence Town
Ferulic acid is a nutraceutical β-secretase modulator that improves behavioral impairment and alzheimer-like pathology in transgenic mice.
PloS one 2013;8(2):e55774.
2012: David Gate; Rachelle Levy; Joshua J Breunig; Moise Danielpour; Terrence Town
Basic biology and mechanisms of neural ciliogenesis and the B9 family.
Molecular neurobiology 2012;45(3):564-70.
2012: Kenichi Shimada; Terrence Town; David M Underhill; Mario Vargas; Laurent Vergnes; Yinsheng Wang; Andrea J Wolf; Shuang Chen; Norika Chiba; Timothy R Crother; Jargalsaikhan Dagvadorj; Katherine A Fitzgerald; Candace Guerrero; Justin Karlin; David M Ojcius; V Krishnan Ramanujan; Altan Rentsendorj; Moshe Arditi
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Immunity 2012;36(3):401-14.
2012: Takashi Mori; Kavon Rezai-Zadeh; Jun Tan; Gary W Arendash; Yuko Horikoshi-Sakuraba; Nobuto Kakuda; Naoki Koyama; Haruyasu Yamaguchi; Terrence Town
Tannic acid is a natural β-secretase inhibitor that prevents cognitive impairment and mitigates Alzheimer-like pathology in transgenic mice.
The Journal of biological chemistry 2012;287(9):6912-27.
2012: Penghua Wang; Long Yang; Xiaoling Yuan; Lauren A Zenewicz; Fengwei Bai; Gong Cheng; Jianfeng Dai; Richard A Flavell; David Gate; Ruth R Montgomery; Feng Qian; Terrence Town; Erol Fikrig
IL-22 signaling contributes to West Nile encephalitis pathogenesis.
PloS one 2012;7(8):e44153.
2012: Tara M Weitz; Terrence Town
Microglia in Alzheimer's Disease: It's All About Context.
International journal of Alzheimer's disease 2012;2012():314185.
2012: Joshua J Breunig; Moise Danielpour; David Gate; Gi Bum Kim; Rachelle Levy; Javier Rodriguez; Clive N Svendsen; Terrence Town
Rapid genetic targeting of pial surface neural progenitors and immature neurons by neonatal electroporation.
Neural development 2012;7():26.
2011: Sariah J Allen; Richard A Flavell; Kevin R Mott; Terrence Town; Steven L Wechsler; Homayon Ghiasi
Adaptive and innate transforming growth factor beta signaling impact herpes simplex virus 1 latency and reactivation.
Journal of virology 2011;85(21):11448-56.
2011: Pearl Gray; Kathrin S Michelsen; Altan Rentsendorj; Terrence Town; Constantinos Brikos; Timothy R Crother; Jargalsaikhan Dagvadorj; Moshe Arditi
Myeloid differentiation factor-2 interacts with Lyn kinase and is tyrosine phosphorylated following lipopolysaccharide-induced activation of the TLR4 signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(8):4331-7.
2011: Enric Esplugues; Jeffrey A Bluestone; Nicola Gagliani; Ann M Haberman; Anja E Hauser; Kevan C Herold; Samuel Huber; Yoichiro Iwakura; Jay K Kolls; Vijay K Kuchroo; William O'Connor; Anthony Rongvaux; Terrence Town; Nico van Rooijen; Yisong Y Wan; Richard A Flavell
Control of TH17 cells occurs in the small intestine.
Nature 2011;475(7357):514-8.
2011: Kavon Rezai-Zadeh; D Gate; G Gowing; Terrence Town
How to get from here to there: macrophage recruitment in Alzheimer's disease.
Current Alzheimer research 2011;8(2):156-63.
2011: Yuyan Zhu; Terrence Town; Yangbing Zhao; Jared Ehrhart; Frank Fernandez; Brian Giunta; Huayan Hou; Dave Morgan; Takashi Mori; William Nikolic; Demian Obregon; Jun Tan
Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology.
Journal of cellular and molecular medicine 2011;15(2):327-38.
2011: Yuyan Zhu; Huayan Hou; Kavon Rezai-Zadeh; Brian Giunta; Amanda Ruscin; Carmelina Gemma; Jingji Jin; Natasa Dragicevic; Patrick Bradshaw; Suhail Rasool; Charles G Glabe; Jared Ehrhart; Paula C Bickford; Takashi Mori; Demian Obregon; Terrence Town; Jun Tan
CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(4):1355-65.
2010: David Gate; Kavon Rezai-Zadeh; Dominique Jodry; Altan Rentsendorj; Terrence Town
Macrophages in Alzheimer's disease: the blood-borne identity.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(8):961-70.
2010: Terrence Town
Alzheimer's Disease Beyond Abeta.
Expert review of neurotherapeutics 2010;10(5):671-5.
2009: Kavon Rezai-Zadeh; David Gate; Terrence Town
CNS infiltration of peripheral immune cells: D-Day for neurodegenerative disease?
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2009;4(4):462-75.
2009: Kavon Rezai-Zadeh; David Gate; Christine A Szekely; Terrence Town
Can peripheral leukocytes be used as Alzheimer's disease biomarkers?
Expert review of neurotherapeutics 2009;9(11):1623-33.
2009: Fengwei Bai; Terrence Town; Qian Feng; Penghua Wang; Masahito Kamanaka; Tarah M Connolly; David Gate; Ruth R Montgomery; Richard A Flavell; Erol Fikrig
IL-10 signaling blockade controls murine West Nile virus infection.
PLoS pathogens 2009;5(10):e1000610.
2009: William O'Connor; Masahito Kamanaka; Carmen J Booth; Terrence Town; Susumu Nakae; Yoichiro Iwakura; Jay K Kolls; Richard A Flavell
A protective function for interleukin 17A in T cell-mediated intestinal inflammation.
Nature immunology 2009;10(6):603-9.
2009: Terrence Town
Alternative Abeta immunotherapy approaches for Alzheimer's disease.
CNS & neurological disorders drug targets 2009;8(2):114-27.
2009: Kavon Rezai-Zadeh; R Douglas Shytle; Yun Bai; Jun Tian; Huayan Hou; Takashi Mori; Jin Zeng; Demian Obregon; Terrence Town; Jun Tan
Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease beta-amyloid production.
Journal of cellular and molecular medicine 2009;13(3):574-88.
2009: Terrence Town; Fengwei Bai; Tian Wang; Amber Kaplan; Qian Feng; Ruth R Montgomery; John F Anderson; Richard A Flavell; Erol Fikrig
Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing.
Immunity 2009;30(2):242-53.
2009: Kevin Mott; David M Underhill; Steven L Wechsler; Terrence Town; Homayon Ghiasi
A role for the JAK-STAT1 pathway in blocking replication of HSV-1 in dendritic cells and macrophages.
Virology journal 2009;6():56.
2009: Derk Amsen; Karin E de Visser; Terrence Town
Approaches to determine expression of inflammatory cytokines.
Methods in molecular biology (Clifton, N.J.) 2009;511():107-42.
2008: Joshua J Breunig; Matthew Sarkisian; Jon I Arellano; Yury M Morozov; Albert E Ayoub; Sonal Sojitra; Baolin Wang; Richard A Flavell; Pasko Rakic; Terrence Town
Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13127-32.
2008: Yasmina Laouar; Terrence Town; David Jeng; Elise Tran; Yisong Y Wan; Vijay K Kuchroo; Richard A Flavell
TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(31):10865-70.
2008: Shuhui Wang; Thomas Welte; Maureen McGargill; Terrence Town; Jesse Thompson; John F Anderson; Richard A Flavell; Erol Fikrig; Stephen M Hedrick; Tian Wang
Drak2 contributes to West Nile virus entry into the brain and lethal encephalitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(3):2084-91.
2008: Takashi Mori; Jun Tan; Gary W Arendash; Naoki Koyama; Yoshiko Nojima; Terrence Town
Overexpression of human S100B exacerbates brain damage and periinfarct gliosis after permanent focal ischemia.
Stroke; a journal of cerebral circulation 2008;39(7):2114-21.
2008: Terrence Town; Yasmina Laouar; Christopher Pittenger; Takashi Mori; Christine A Szekely; Jun Tan; Ronald S Duman; Richard A Flavell
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology.
Nature medicine 2008;14(6):681-7.
2008: William V Nikolic; Huayan Hou; Terrence Town; Yuyan Zhu; Brian Giunta; Cyndy Davis Sanberg; Jin Zeng; Deyan Luo; Jared Ehrhart; Takashi Mori; Paul Sanberg; Jun Tan
Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice.
Stem cells and development 2008;17(3):423-39.
2008: Subhasis Mohanty; Terrence Town; Tomohito Yagi; Christina Scheidig; Kelvin Y Kwan; Heather G Allore; Richard A Flavell; Tomohito Yagi
Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3beta.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(13):5063-8.
2008: Jianfeng Dai; Penghua Wang; Fengwei Bai; Terrence Town; Erol Fikrig
Icam-1 participates in the entry of west nile virus into the central nervous system.
Journal of virology 2008;82(8):4164-8.
2008: Terrence Town; Joshua J Breunig; Matthew Sarkisian; Charalampos Spilianakis; Albert E Ayoub; Xiuxin Liu; Anthony F Ferrandino; Anna Rachel Gallagher; Ming O Li; Pasko Rakic; Richard A Flavell
The stumpy gene is required for mammalian ciliogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(8):2853-8.
2008: Demian Obregon; H Hou; Y Bai; W V Nikolic; T Mori; Deyan Luo; J Zeng; Jared Ehrhart; F Fernandez; Dave Morgan; Brian Giunta; Terrence Town; Jun Tan
CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
Neurobiology of disease 2008;29(2):336-53.
2008: Brian Giunta; Francisco Fernandez; William V Nikolic; Demian Obregon; Elona Rrapo; Terrence Town; Jun Tan
Inflammaging as a prodrome to Alzheimer's disease.
Journal of neuroinflammation 2008;5():51.
2007: Alvaro Arjona; Michel Ledizet; Karen Anthony; Nathalie Bonafe; Yorgo Modis; Terrence Town; Erol Fikrig
West Nile virus envelope protein inhibits dsRNA-induced innate immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8403-9.
2007: Jason W Griffith; Christine O'Connor; Ken Bernard; Terrence Town; Daniel R Goldstein; Richard Bucala
Toll-like receptor modulation of murine cerebral malaria is dependent on the genetic background of the host.
The Journal of infectious diseases 2007;196(10):1553-64.
2007: Jonathan Deane; Prapaporn Pisitkun; Rebecca S Barrett; Lionel Feigenbaum; Terrence Town; Jerrold M Ward; Richard A Flavell; Silvia Bolland
Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation.
Immunity 2007;27(5):801-10.
2007: Azuma Watanabe; Ardeshir Hashmi; Dawidson Gomes; Terrence Town; Abdallah Badou; Richard Anthony Flavell; Wajahat Z Mehal
Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9.
Hepatology (Baltimore, Md.) 2007;46(5):1509-18.
2007: Alvaro Arjona; Harald G Foellmer; Terrence Town; Lin Leng; Courtney McDonald; Tian Wang; Susan J Wong; Ruth R Montgomery; Erol Fikrig; Richard Bucala
Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion.
The Journal of clinical investigation 2007;117(10):3059-66.
2007: William V Nikolic; Yun Bai; Demian Obregon; Huayan Hou; Takashi Mori; Jin Zeng; Jared Ehrhart; R Douglas Shytle; Brian Giunta; Dave Morgan; Terrence Town; Jun Tan
Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(7):2507-12.
2007: Fengwei Bai; Terrence Town; Deepti Pradhan; Jonathan Cox; Michel Ledizet; John F Anderson; Richard A Flavell; Joanna K Krueger; Raymond A Koski; Erol Fikrig
Antiviral peptides targeting the west nile virus envelope protein.
Journal of virology 2007;81(4):2047-55.
2007: Christine A Szekely; Terrence Town; Peter P Zandi
NSAIDs for the chemoprevention of Alzheimer's disease.
Sub-cellular biochemistry 2007;42():229-48.
2006: Ruibo Wang; Terrence Town; Varun Gokarn; Richard A Flavell; Rajiv Y Chandawarkar
HSP70 enhances macrophage phagocytosis by interaction with lipid raft-associated TLR-7 and upregulating p38 MAPK and PI3K pathways.
The Journal of surgical research 2006;136(1):58-69.
2006: Takashi Mori; Terrence Town; Jun Tan; Nobumichi Yada; Yuko Horikoshi; Junki Yamamoto; Taiji Shimoda; Yoshihisa Kamanaka; Narito Tateishi; Takao Asano
Arundic Acid ameliorates cerebral amyloidosis and gliosis in Alzheimer transgenic mice.
The Journal of pharmacology and experimental therapeutics 2006;318(2):571-8.
2006: Demian Obregon; Kavon Rezai-Zadeh; Yun Bai; Nan Sun; Huayan Hou; Jared Ehrhart; Jin Zeng; Takashi Mori; Gary W Arendash; Doug Shytle; Terrence Town; Jun Tan
ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein.
The Journal of biological chemistry 2006;281(24):16419-27.
2006: Terrence Town; David Jeng; Lena Alexopoulou; Jun Tan; Richard A Flavell
Microglia recognize double-stranded RNA via TLR3.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3804-12.
2005: Terrence Town; Veljko Nikolic; Jun Tan
The microglial "activation" continuum: from innate to adaptive responses.
Journal of neuroinflammation 2005;2():24.
2005: Kavon Rezai-Zadeh; Doug Shytle; Nan Sun; Takashi Mori; Huayan Hou; Deborah Jeanniton; Jared Ehrhart; Kirk Townsend; Jin Zeng; Dave Morgan; John Hardy; Terrence Town; Jun Tan
Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(38):8807-14.
2005: W Taylor Kimberly; Jessica B Zheng; Terrence Town; Richard A Flavell; Dennis J Selkoe
Physiological regulation of the beta-amyloid precursor protein signaling domain by c-Jun N-terminal kinase JNK3 during neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(23):5533-43.
2005: Charalampos Spilianakis; Maria D Lalioti; Terrence Town; Gap Ryol Lee; Richard A Flavell
Interchromosomal associations between alternatively expressed loci.
Nature 2005;435(7042):637-45.
2005: Takashi Mori; Terrence Town; Jun Tan; Narito Tateishi; Takao Asano
Modulation of astrocytic activation by arundic acid (ONO-2506) mitigates detrimental effects of the apolipoprotein E4 isoform after permanent focal ischemia in apolipoprotein E knock-in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(6):748-62.
2005: Kirk P Townsend; Terrence Town; Takashi Mori; Lih-Fen Lue; Doug Shytle; Paul Sanberg; Dave Morgan; Francisco Fernandez; Richard A Flavell; Jun Tan
CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide.
European journal of immunology 2005;35(3):901-10.
2005: Terrence Town; Jun Tan; Richard A Flavell; Michael Mullan
T-cells in Alzheimer's disease.
Neuromolecular medicine 2005;7(3):255-64.
2004: Tian Wang; Terrence Town; Lena Alexopoulou; John F Anderson; Erol Fikrig; Richard A Flavell
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis.
Nature medicine 2004;10(12):1366-73.
2004: J Todd Roach; Claude-Henry Volmar; Samvid Dwivedi; Terrence Town; Robert Crescentini; Fiona Crawford; Jun Tan; Michael Mullan
Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.
Brain research 2004;1015(1-2):161-8.
2004: Takashi Mori; Terrence Town; Mariko Kobayashi; Jun Tan; Shinobu C Fujita; Takao Asano
Augmented delayed infarct expansion and reactive astrocytosis after permanent focal ischemia in apolipoprotein E4 knock-in mice.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2004;24(6):646-56.
2004: Kirk P Townsend; Martina Vendrame; Jared Ehrhart; Brandon Faza; Jin Zeng; Terrence Town; Jun Tan
CD45 isoform RB as a molecular target to oppose lipopolysaccharide-induced microglial activation in mice.
Neuroscience letters 2004;362(1):26-30.
2004: Ryan T Mott; Ghania Ait-Ghezala; Terrence Town; Takashi Mori; Martina Vendrame; Jin Zeng; Jared Ehrhart; Michael Mullan; Jun Tan
Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production.
Glia 2004;46(4):369-79.
2003: Takashi Mori; Mariko Kobayashi; Terrence Town; Shinobu C Fujita; Takao Asano
Increased vulnerability to focal ischemic brain injury in human apolipoprotein E4 knock-in mice.
Journal of neuropathology and experimental neurology 2003;62(3):280-91.
2002: Jun Tan; Terrence Town; Fiona Crawford; Takashi Mori; Anthony DelleDonne; Robert Crescentini; Demian Obregon; Richard A Flavell; Michael Mullan
Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.
Nature neuroscience 2002;5(12):1288-93.
2002: Jun Tan; Terrence Town; Laila Abdullah; Yajaun Wu; Andon Placzek; Brent Small; Jodi Kroeger; Fiona Crawford; Dan Richards; Michael Mullan
CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease.
Journal of neuroimmunology 2002;132(1-2):164-72.
2002: Terrence Town; Martina Vendrame; Anant Patel; Daniel Poetter; Anthony DelleDonne; Takashi Mori; Robert Smeed; Fiona Crawford; Thomas Klein; Jun Tan; Michael Mullan
Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42).
Journal of neuroimmunology 2002;132(1-2):49-59.
2002: Jun Tan; Terrence Town; Michael Mullan
CD40-CD40L interaction in Alzheimer's disease.
Current opinion in pharmacology 2002;2(4):445-51.
2002: Terrence Town; Joseph Zolton; Reed Shaffner; Billy Schnell; Robert Crescentini; Yajuan Wu; Jin Zeng; Anthony DelleDonne; Demian Obregon; Jun Tan; Michael Mullan
p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.
Journal of neuroscience research 2002;69(3):362-72.
2002: Ghania Ait-Ghezala; Laila Abdullah; Robert Crescentini; Fiona Crawford; Terrence Town; S Singh; D Richards; Ranjan Duara; Michael Mullan
Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.
Neuroscience letters 2002;325(2):87-90.
2002: Jun Tan; Terrence Town; Takashi Mori; Demian Obregon; Yajuan Wu; Anthony DelleDonne; Amyn M Rojiani; Fiona Crawford; Richard A Flavell; Michael Mullan
CD40 is expressed and functional on neuronal cells.
The EMBO journal 2002;21(4):643-52.
2002: John A Schinka; Terrence Town; Laila Abdullah; Fiona C Crawford; Patricia Isbell Ordorica; E Francis; P Hughes; A B Graves; James A Mortimer; Michael Mullan
A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances.
Molecular psychiatry 2002;7(2):224-8.
2001: Terrence Town; Jun Tan; Michael Mullan
CD40 signaling and Alzheimer's disease pathogenesis.
Neurochemistry international 2001;39(5-6):371-80.
2001: Takashi Mori; Daniel Paris; Terrence Town; Amyn M Rojiani; D Larry Sparks; Anthony DelleDonne; Fiona Crawford; Laila Abdullah; J A Humphrey; dennis dickson; Michael Mullan
Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice.
Journal of neuropathology and experimental neurology 2001;60(8):778-85.
2001: Terrence Town; Jun Tan; N Sansone; Demian Obregon; T Klein; Michael Mullan
Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42.
Neuroscience letters 2001;307(2):101-4.
2001: T Mori; K Nagata; Terrence Town; Jun Tan; T Matsui; T Asano
Intracisternal increase of superoxide anion production in a canine subarachnoid hemorrhage model.
Stroke; a journal of cerebral circulation 2001;32(3):636-42.
2000: Terrence Town; John A Schinka; Jun Tan; Michael Mullan
The opioid receptor system and alcoholism: a genetic perspective.
European journal of pharmacology 2000;410(2-3):243-248.
2000: Jun Tan; Terrence Town; Michael Mullan
CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway.
The Journal of biological chemistry 2000;275(47):37224-31.
2000: Jun Tan; Terrence Town; Takashi Mori; Y Wu; M Saxe; Fiona Crawford; Michael Mullan
CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(20):7587-94.
2000: Daniel Paris; Terrence Town; James Humphrey; K Yokota; Michael Mullan
Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway.
Biochemical and biophysical research communications 2000;274(2):553-8.
2000: Daniel Paris; Terrence Town; T Parker; James Humphrey; Michael Mullan
beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating agents.
Annals of the New York Academy of Sciences 2000;903():446-50.
2000: Daniel Paris; Terrence Town; T Parker; James Humphrey; Michael Mullan
A beta vasoactivity: an inflammatory reaction.
Annals of the New York Academy of Sciences 2000;903():97-109.
2000: Daniel Paris; Terrence Town; T Mori; TA Parker; James Humphrey; Michael Mullan
Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway.
Neurobiology of aging 2000;21(2):183-97.
2000: Daniel Paris; Terrence Town; Michael Mullan
Novel strategies for opposing murine microglial activation.
Neuroscience letters 2000;278(1-2):5-8.
1999: Jun Tan; Terrence Town; Daniel Paris; T Mori; Z Suo; Fiona Crawford; Mark P Mattson; R A Flavell; Michael Mullan
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.
Science (New York, N.Y.) 1999;286(5448):2352-5.
1999: Jun Tan; Terrence Town; M Saxe; Daniel Paris; Yajuan Wu; Michael Mullan
Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6614-21.
1999: Terrence Town; Daniel Paris; T A Parker; A Kundtz; Jun Tan; Ranjan Duara; M Gold; Fiona Crawford; Michael Mullan
Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E.
American journal of medical genetics 1999;88(5):465-8.
1999: Terrence Town; Laila Abdullah; Fiona Crawford; John A Schinka; Patricia Isbell Ordorica; E Francis; P Hughes; Ranjan Duara; Michael Mullan
Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency.
American journal of medical genetics 1999;88(5):458-61.
1999: Jun Tan; Terrence Town; Z Suo; Y Wu; S Song; A Kundtz; J Kroeger; James Humphrey; Fiona Crawford; Michael Mullan
Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides.
Brain research bulletin 1999;50(2):143-8.
1999: Jun Tan; Terrence Town; Andon Placzek; A Kundtz; H Yu; Michael Mullan
Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in PC12 cells.
Neuroscience letters 1999;272(1):5-8.
1999: Fiona Crawford; Terrence Town; M Freeman; John A Schinka; M Gold; Ranjan Duara; Michael Mullan
The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample.
Neuroscience letters 1999;270(3):133-6.
1999: Jun Tan; Terrence Town; Daniel Paris; Andon Placzek; T Parker; Fiona Crawford; H Yu; James Humphrey; Michael Mullan
Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis.
Journal of neuroimmunology 1999;97(1-2):77-85.
1999: Fiona Crawford; M Freeman; Terrence Town; D Fallin; M Gold; Ranjan Duara; Michael Mullan
No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples.
Neuroscience letters 1999;266(3):193-6.
1999: Daniel Paris; Terrence Town; TA Parker; Jun Tan; James Humphrey; Fiona Crawford; Michael Mullan
Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism.
Experimental neurology 1999;157(1):211-21.
1998: Daniel Paris; Terrence Town; TA Parker; James Humphrey; Michael Mullan
Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's beta-amyloid peptide.
Neuroscience letters 1998;256(2):73-6.
1998: Terrence Town; Daniel Paris; D Fallin; Ranjan Duara; W Barker; M Gold; Fiona Crawford; Michael Mullan
The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism.
Neuroscience letters 1998;252(2):95-8.
1998: Daniel Paris; TA Parker; Terrence Town; Z Suo; C Fang; James Humphrey; Fiona Crawford; Michael Mullan
Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide.
Experimental neurology 1998;152(1):116-22.
1997: D Fallin; A Kundtz; Terrence Town; AC Gauntlett; Ranjan Duara; W Barker; Fiona Crawford; Michael Mullan
No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample.
Neuroscience letters 1997;233(2-3):145-7.
1997: Terrence Town; D Fallin; Fiona Crawford; S Walsh; R Solomon; Michael Mullan
Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic schizophrenia.
American journal of medical genetics 1997;74(4):451-2.