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Bernard Candas

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Fernand Labrie; Alain Bélanger; Claude Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez
Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women.
Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Véronique Chaussade; Isabelle Castiel; Claire Deloche; Jacques Leclaire
Metabolism of DHEA in postmenopausal women following percutaneous administration.
Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Isabelle Castiel; Véronique Chaussade; Claire Deloche; Jacques Leclaire
Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women.

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All Publications

2007: Fernand Labrie; Alain Bélanger; Claude Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez
Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women.
The Journal of steroid biochemistry and molecular biology 2007;107(1-2):57-69.
2007: Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Véronique Chaussade; Isabelle Castiel; Claire Deloche; Jacques Leclaire
Metabolism of DHEA in postmenopausal women following percutaneous administration.
The Journal of steroid biochemistry and molecular biology 2007;103(2):178-88.
2006: Fernand Labrie; Alain Bélanger; Patrick Bélanger; René Bérubé; Céline Martel; Leonello Cusan; José Gomez; Bernard Candas; Isabelle Castiel; Véronique Chaussade; Claire Deloche; Jacques Leclaire
Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women.
The Journal of steroid biochemistry and molecular biology 2006;99(4-5):182-8.
2006: Bernard Candas; Fernand Labrie; José Luis Gomez; Leonello Cusan; Eric Chevrette; Jacques Lévesque; Ghyslain Brousseau
Relationship among initial serum prostate specific antigen, prostate specific antigen progression and prostate cancer detection at repeat screening visits.
The Journal of urology 2006;175(2):510-6; discussion 516-7.
2005: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Gomez; Bernard Candas
Gonadotropin-releasing hormone agonists in the treatment of prostate cancer.
Endocrine reviews 2005;26(3):361-79.
2004: Fernand Labrie; Leonello Cusan; José Gomez; Van Luu-The; Bernard Candas; Alain Bélanger; Claude Labrie
Major impact of hormonal therapy in localized prostate cancer--death can already be an exception.
The Journal of steroid biochemistry and molecular biology 2004;92(5):327-44.
2004: Fernand Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez; Alain Bélanger; Ghyslain Brousseau; Eric Chevrette; Jacques Lévesque
Screening decreases prostate cancer mortality: 11-year follow-up of the 1988 Quebec prospective randomized controlled trial.
The Prostate 2004;59(3):311-8.
2004: Fernand Labrie; Patrick Champagne; Claude Labrie; Jean Roy; Jacques Laverdière; Louise Provencher; Martin Potvin; Yvan Drolet; Michael Pollak; Lawrence Panasci; Bernard L'Espérance; Jean Dufresne; Jean Latreille; Jean Robert; Benoît Samson; Jacques Jolivet; Louise Yelle; Leonello Cusan; Pierre Diamond; Bernard Candas
Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(5):864-71.
2003: Fernand Labrie; Mohamed El-Alfy; Louise Berger; Claude Labrie; Céline Martel; Alain Bélanger; Bernard Candas; Georges Pelletier
The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health?
Endocrinology 2003;144(11):4700-6.
2003: Fernand Labrie; Leonello Cusan; José Luis Gomez; Bernard Candas; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard
[From the gene to the clinic: prostate cancer death can now be an exception?].
Médecine sciences : M/S 2003;19(10):910-9.
2003: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey.
The Journal of clinical endocrinology and metabolism 2003;88(9):4293-302.
2003: Mathieu Gutmann; Steeve Couillard; Fernand Labrie; Bernard Candas; Claude Labrie
Effect of treatment sequence with radiotherapy and the antiestrogen EM 800 on the growth of ZR 75 1 human mammary carcinoma in nude mice.
International journal of cancer. Journal international du cancer 2003;103(2):268-76.
2002: Fernand Labrie; Bernard Candas
Interpreting the Quebec prostate cancer study.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2002;167(4):340.
2002: Fernand Labrie; Bernard Candas; José Luis Gomez; Leonello Cusan
Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer?
Urology 2002;60(1):115-9.
2002: Mathias Leblanc; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey.
The Journal of steroid biochemistry and molecular biology 2002;81(2):159-64.
2002: Mathieu Gutmann; Steeve Couillard; Jenny Roy; Fernand Labrie; Bernard Candas; Claude Labrie
Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice.
International journal of cancer. Journal international du cancer 2002;99(2):273-8.
2001: Fernand Labrie; Claude Labrie; Alain Bélanger; V Giguere; Jacques Simard; Yves Mérand; Sylvain Gauthier; Van Luu-The; Bernard Candas; Céline Martel; S Luo
Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities.
Advances in protein chemistry 2001;56():293-368.
2000: Bernard Candas; Leonello Cusan; José Luis Gomez; Pierre Diamond; RE Suburu; Jacques Lévesque; Ghyslain Brousseau; Alain Bélanger; Fernand Labrie
Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer.
The Prostate 2000;45(1):19-35.
2000: Steeve Couillard; Claude Labrie; Sylvain Gauthier; Y Merand; SM Singh; Bernard Candas; Fernand Labrie
Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice.
International journal of cancer. Journal international du cancer 2000;85(3):424-9.
1999: Mathieu Gutmann; Steeve Couillard; Fernand Labrie; Bernard Candas; Claude Labrie
Effects of the antiestrogen EM-800 (SCH 57050) and cyclophosphamide alone and in combination on growth of human ZR-75-1 breast cancer xenografts in nude mice.
Cancer research 1999;59(20):5176-80.
1999: Steeve Couillard; Mathieu Gutmann; Fernand Labrie; Bernard Candas; Claude Labrie
Effect of combined treatment with the pure antiestrogen EM-800 and radiotherapy on the growth of human ZR-75-1 breast cancer xenografts in nude mice.
Cancer research 1999;59(19):4857-63.
1999: Fernand Labrie; Claude Labrie; Alain Bélanger; Jacques Simard; Sylvain Gauthier; Van Luu-The; Yves Mérand; V Giguere; Bernard Candas; S Luo; Céline Martel; SM Singh; M Fournier; A Coquet; V Richard; R Charbonneau; G Charpenet; A Tremblay; G Tremblay; Leonello Cusan; R Veilleux
EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):51-84.
1999: Theo Van der Kwast; B Têtu; Bernard Candas; José Luis Gomez; Leonello Cusan; Fernand Labrie
Prolonged neoadjuvant combined androgen blockade leads to a further reduction of prostatic tumor volume: three versus six months of endocrine therapy.
Urology 1999;53(3):523-9.
1999: Fernand Labrie; Bernard Candas; A Dupont; Leonello Cusan; José Luis Gomez; RE Suburu; Pierre Diamond; Jacques Lévesque; A Belanger
Screening decreases prostate cancer death: first analysis of the 1988 Quebec prospective randomized controlled trial.
The Prostate 1999;38(2):83-91.
1998: Steeve Couillard; Claude Labrie; Alain Bélanger; Bernard Candas; Frédéric Pouliot; Fernand Labrie
Effect of dehydroepiandrosterone and the antiestrogen EM-800 on growth of human ZR-75-1 breast cancer xenografts.
Journal of the National Cancer Institute 1998;90(10):772-8.
1998: S Luo; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Prevention of development of dimethylbenz(a)anthracene (DMBA)-induced mammary tumors in the rat by the new nonsteroidal antiestrogen EM-800 (SCH57050).
Breast cancer research and treatment 1998;49(1):1-11.
1998: Fernand Labrie; Alain Bélanger; Van Luu-The; Claude Labrie; Jacques Simard; Leonello Cusan; José Luis Gomez; Bernard Candas
DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging.
Steroids 1998;63(5-6):322-8.
1998: Céline Martel; Claude Labrie; Alain Bélanger; Sylvain Gauthier; Yves Mérand; X Li; Louise Provencher; Bernard Candas; Fernand Labrie
Comparison of the effects of the new orally active antiestrogen EM-800 with ICI 182 780 and toremifene on estrogen-sensitive parameters in the ovariectomized mouse.
Endocrinology 1998;139(5):2486-92.
1998: Steeve Couillard; Mathieu Gutmann; Claude Labrie; Alain Bélanger; Bernard Candas; Fernand Labrie
Comparison of the effects of the antiestrogens EM-800 and tamoxifen on the growth of human breast ZR-75-1 cancer xenografts in nude mice.
Cancer research 1998;58(1):60-4.
1997: S Luo; Céline Martel; C Chen; Claude Labrie; Bernard Candas; S M Singh; Fernand Labrie
Daily dosing with flutamide or Casodex exerts maximal antiandrogenic activity.
Urology 1997;50(6):913-9.
1997: Fernand Labrie; Pierre Diamond; Leonello Cusan; José Luis Gomez; Alain Bélanger; Bernard Candas
Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women.
The Journal of clinical endocrinology and metabolism 1997;82(10):3498-505.
1997: Fernand Labrie; Alain Bélanger; Leonello Cusan; Bernard Candas
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.
The Journal of clinical endocrinology and metabolism 1997;82(8):2403-9.
1997: Fernand Labrie; Alain Bélanger; Leonello Cusan; José Luis Gomez; Bernard Candas
Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
The Journal of clinical endocrinology and metabolism 1997;82(8):2396-402.
1997: Fernand Labrie; Leonello Cusan; José Luis Gomez; P Diamond; RE Suburu; M Lemay; B Tetu; Y Fradet; Alain Bélanger; Bernard Candas
Neoadjuvant hormonal therapy: the Canadian experience.
Urology 1997;49(3A Suppl):56-64.
1997: Jacques Laverdière; José Luis Gomez; Leonello Cusan; E R Suburu; P Diamond; M Lemay; Bernard Candas; André Fortin; Fernand Labrie
Beneficial effect of combination hormonal therapy administered prior and following external beam radiation therapy in localized prostate cancer.
International journal of radiation oncology, biology, physics 1997;37(2):247-52.
1996: Fernand Labrie; Bernard Candas; Leonello Cusan; José Luis Gomez; Pierre Diamond; R Suburu; M Lemay
Diagnosis of advanced or noncurable prostate cancer can be practically eliminated by prostate-specific antigen.
Urology 1996;47(2):212-7.
1996: L Vailancourt; B Ttu; Y Fradet; A Dupont; J Gomez; Leonello Cusan; E R Suburu; Pierre Diamond; Bernard Candas; Fernand Labrie
Effect of neoadjuvant endocrine therapy (combined androgen blockade) on normal prostate and prostatic carcinoma. A randomized study.
The American journal of surgical pathology 1996;20(1):86-93.
1995: Fernand Labrie; Leonello Cusan; José Luis Gomez; Pierre Diamond; Bernard Candas
Combination of screening and preoperative endocrine therapy: the potential for an important decrease in prostate cancer mortality.
The Journal of clinical endocrinology and metabolism 1995;80(7):2002-13.
1995: Fernand Labrie; Leonello Cusan; José Luis Gomez; Pierre Diamond; R Suburu; M Lemay; B Têtu; Y Fradet; Bernard Candas
Downstaging by combination therapy with flutamide and an LHRH agonist before radical prostatectomy.
Cancer surveys 1995;23():149-56.
1994: Alain Bélanger; Bernard Candas; A Dupont; Leonello Cusan; Pierre Diamond; José Luis Gomez; Fernand Labrie
Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men.
The Journal of clinical endocrinology and metabolism 1994;79(4):1086-90.
1993: Fernand Labrie; A Dupont; R Suburu; Leonello Cusan; José Luis Gomez; M Koutsilieris; Pierre Diamond; J Emond; M Lemay; Bernard Candas
Optimized strategy for detection of early stage, curable prostate cancer: role of prescreening with prostate-specific antigen.
Clinical and investigative medicine. Médecine clinique et experimentale 1993;16(6):425-39.
1990: Bernard Candas; D Lacoste; M Normand; F Labrie
Model of the distribution and metabolism of the gonadotropin-releasing hormone (GnRH) agonist [D-Trp6,Des-Gly-NH2(10)]GnRH ethylamide in man.
The Journal of clinical endocrinology and metabolism 1990;70(4):1046-54.
1990: D Lacoste; Bernard Candas; M Normand; F Labrie
Model of the distribution and metabolism of a GnRH superagonist in dogs.
The American journal of physiology 1990;258(3 Pt 1):E468-75.
1989: Pierre Diamond; G R Brisson; Bernard Candas; F Péronnet
Trait anxiety, submaximal physical exercise and blood androgens.
European journal of applied physiology and occupational physiology 1989;58(7):699-704.
1988: Bernard Candas; J Lalonde; M Normand
A model of the distribution and metabolism of corticotropin-releasing factor.
The American journal of physiology 1988;254(1 Pt 1):E104-12.
1986: Bernard Candas; J Lalonde; M Normand
Distribution and metabolism of corticotropin-releasing factor in the rat.
Canadian journal of physiology and pharmacology 1986;64(6):683-8.