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Christine Van Broeckhoven

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Bettens Karolien; Brouwers Nathalie; Engelborghs Sebastiaan; De Pooter Tim; De Deyn Peter P; Sleegers Kristel; Van Broeckhoven Christine
DNMBP is genetically associated with Alzheimer dementia in the Belgian population.
Dintchov Traykov Latchezar; Mehrabian Shima; Van den Broeck Marleen; Radoslavova Raycheva Margarita; Cruts Marc; Kirilova Jordanova Albena; Van Broeckhoven Christine
Novel PSEN1 mutation in a bulgarian patient with very early-onset Alzheimer's disease, spastic paraparesis, and extrapyramidal signs.
Pereson Sandra; Wils Hans; Kleinberger Gernot; McGowan Eileen; Vandewoestyne Mado; Van Broeck Bianca; Joris Geert; Cuijt Ivy; Deforce Dieter; Hutton Michael; Van Broeckhoven Christine; Kumar-Singh Samir
Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.

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All Publications

2009: Bettens Karolien; Brouwers Nathalie; Engelborghs Sebastiaan; De Pooter Tim; De Deyn Peter P; Sleegers Kristel; Van Broeckhoven Christine
DNMBP is genetically associated with Alzheimer dementia in the Belgian population.
Neurobiology of aging 2009;30(12):2000-9.
2009: Dintchov Traykov Latchezar; Mehrabian Shima; Van den Broeck Marleen; Radoslavova Raycheva Margarita; Cruts Marc; Kirilova Jordanova Albena; Van Broeckhoven Christine
Novel PSEN1 mutation in a bulgarian patient with very early-onset Alzheimer's disease, spastic paraparesis, and extrapyramidal signs.
American journal of Alzheimer's disease and other dementias 2009;24(5):404-7.
2009: Pereson Sandra; Wils Hans; Kleinberger Gernot; McGowan Eileen; Vandewoestyne Mado; Van Broeck Bianca; Joris Geert; Cuijt Ivy; Deforce Dieter; Hutton Michael; Van Broeckhoven Christine; Kumar-Singh Samir
Progranulin expression correlates with dense-core amyloid plaque burden in Alzheimer disease mouse models.
The Journal of pathology 2009;219(2):173-81.
2009: van der Zee J; Pirici D; Van Langenhove T; Engelborghs S; Vandenberghe R; Hoffmann M; Pusswald G; Van den Broeck M; Peeters K; Mattheijssens M; Martin J-J; De Deyn P P; Cruts M; Haubenberger D; Kumar-Singh S; Zimprich A; Van Broeckhoven C
Clinical heterogeneity in 3 unrelated families linked to VCP p.Arg159His.
Neurology 2009;73(8):626-32.
2009: Bettens Karolien; Brouwers Nathalie; Engelborghs Sebastiaan; Van Miegroet Helen; De Deyn Peter P; Theuns Jessie; Sleegers Kristel; Van Broeckhoven Christine
APP and BACE1 miRNA genetic variability has no major role in risk for Alzheimer disease.
Human mutation 2009;30(8):1207-13.
2009: Gijselinck Ilse; Sleegers Kristel; Engelborghs Sebastiaan; Robberecht Wim; Martin Jean-Jacques; Vandenberghe Rik; Sciot Raf; Dermaut Bart; Goossens Dirk; van der Zee Julie; De Pooter Tim; Del-Favero Jurgen; Santens Patrick; De Jonghe Peter; De Deyn Peter P; Van Broeckhoven Christine; Cruts Marc
Neuronal inclusion protein TDP-43 has no primary genetic role in FTD and ALS.
Neurobiology of aging 2009;30(8):1329-31.
2009: Harbo H F; Finsterer J; Baets J; Van Broeckhoven C; Di Donato S; Fontaine B; De Jonghe P; Lossos A; Lynch T; Mariotti C; Schöls L; Spinazzola A; Szolnoki Z; Tabrizi S J; Tallaksen C; Zeviani M; Burgunder J-M; Gasser T;
EFNS guidelines on the molecular diagnosis of neurogenetic disorders: general issues, Huntington's disease, Parkinson's disease and dystonias.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(7):777-85.
2009: Nuytemans Karen; Meeus Bram; Crosiers David; Brouwers Nathalie; Goossens Dirk; Engelborghs Sebastiaan; Pals Philippe; Pickut Barbara; Van den Broeck Marleen; Corsmit Ellen; Cras Patrick; De Deyn Peter P; Del-Favero Jurgen; Van Broeckhoven Christine; Theuns Jessie
Relative contribution of simple mutations vs. copy number variations in five Parkinson disease genes in the Belgian population.
Human mutation 2009;30(7):1054-61.
2009: Sleegers Kristel; Brouwers Nathalie; Van Damme Philip; Engelborghs Sebastiaan; Gijselinck Ilse; van der Zee Julie; Peeters Karin; Mattheijssens Maria; Cruts Marc; Vandenberghe Rik; De Deyn Peter P; Robberecht Wim; Van Broeckhoven Christine
Serum biomarker for progranulin-associated frontotemporal lobar degeneration.
Annals of neurology 2009;65(5):603-9.
2009: van West Dirk; Del-Favero Jurgen; Deboutte Dirk; Van Broeckhoven Christine; Claes Stephan
Arginine vasopressin receptor gene-based single-nucleotide polymorphism analysis in attention deficit hyperactivity disorder.
Psychiatric genetics 2009;19(2):102-3.
2009: Sleegers Kristel; Brouwers Nathalie; Bettens Karolien; Engelborghs Sebastiaan; van Miegroet Helen; De Deyn Peter P; Van Broeckhoven Christine
No association between CALHM1 and risk for Alzheimer dementia in a Belgian population.
Human mutation 2009;30(4):E570-4.
2009: Sleegers Kristel; Van Broeckhoven Christine
Motor-neuron disease: Rogue gene in the family.
Nature 2009;458(7237):415-7.
2009: Gankam Kengne F; Vokaer M; Fery P; Abramowicz M; Massat I; Van den Broeck M; Van Broeckhoven C; Bier J-C
Pure progressive amnesia as variant of genetically proven Alzheimer disease.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(2):e9-10.
2009: Sleegers Kristel; Bettens Karolien; Brouwers Nathalie; Engelborghs Sebastiaan; van Miegroet Helen; De Deyn Peter P; Van Broeckhoven Christine
Common variation in GRB-associated Binding Protein 2 (GAB2) and increased risk for Alzheimer dementia.
Human mutation 2009;30(2):E338-44.
2009: Matimba Alice; Del-Favero Jurgen; Van Broeckhoven Christine; Masimirembwa Collen
Novel variants of major drug-metabolising enzyme genes in diverse African populations and their predicted functional effects.
Human genomics 2009;3(2):169-90.
2009: Vandenberghe Wim; Van Laere Koen; Debruyne Frederik; Van Broeckhoven Christine; Van Goethem Gert
Neurodegenerative Parkinsonism and progressive external ophthalmoplegia with a Twinkle mutation.
Movement disorders : official journal of the Movement Disorder Society 2009;24(2):308-9.
2009: Liu Fan; Ikram M Arfan; Janssens A Cecile J W; Schuur Maaike; de Koning Inge; Isaacs Aaron; Struchalin Maksim; Uitterlinden Andre G; den Dunnen Johan T; Sleegers Kristel; Bettens Karolien; Van Broeckhoven Christine; van Swieten John; Hofman Albert; Oostra Ben A; Aulchenko Yurii S; Breteler Monique M B; van Duijn Cornelia M
A study of the SORL1 gene in Alzheimer's disease and cognitive function.
Journal of Alzheimer's disease : JAD 2009;18(1):51-64.
2008: Aulchenko Yurii S; Hoppenbrouwers Ilse A; Ramagopalan Sreeram V; Broer Linda; Jafari Naghmeh; Hillert Jan; Link Jenny; Lundström Wangko; Greiner Eva; Dessa Sadovnick A; Goossens Dirk; Van Broeckhoven Christine; Del-Favero Jurgen; Ebers George C; Oostra Ben A; van Duijn Cornelia M; Hintzen Rogier Q
Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis.
Nature genetics 2008;40(12):1402-3.
2008: Van Broeck Bianca; Vanhoutte Greet; Cuijt Ivy; Pereson Sandra; Joris Geert; Timmermans Jean-Pierre; Van der Linden Annemie; Van Broeckhoven Christine; Kumar-Singh Samir
Reduced brain volumes in mice expressing APP-Austrian mutation but not in mice expressing APP-Swedish-Austrian mutations.
Neuroscience letters 2008;447(2-3):143-7.
2008: Gijselinck I; Van Broeckhoven C; Cruts M
Granulin mutations associated with frontotemporal lobar degeneration and related disorders: an update.
Human mutation 2008;29(12):1373-86.
2008: van der Zee Julie; Sleegers Kristel; Van Broeckhoven Christine
Invited article: the Alzheimer disease-frontotemporal lobar degeneration spectrum.
Neurology 2008;71(15):1191-7.
2008: Nuytemans K; Pals P; Sleegers K; Engelborghs S; Corsmit E; Peeters K; Pickut B; Mattheijssens M; Cras P; De Deyn P P; Theuns J; Van Broeckhoven C
Progranulin variability has no major role in Parkinson disease genetic etiology.
Neurology 2008;71(15):1147-51.
2008: Hoche F; Seidel K; Brunt E R; Auburger G; Schöls L; Bürk K; de Vos R A; den Dunnen W; Bechmann I; Egensperger R; Van Broeckhoven C; Gierga K; Deller T; Rüb U
Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7).
Neuropathology and applied neurobiology 2008;34(5):479-91.
2008: Brouwers N; Sleegers K; Engelborghs S; Maurer-Stroh S; Gijselinck I; van der Zee J; Pickut B A; Van den Broeck M; Mattheijssens M; Peeters K; Schymkowitz J; Rousseau F; Martin J-J; Cruts M; De Deyn P P; Van Broeckhoven C
Genetic variability in progranulin contributes to risk for clinically diagnosed Alzheimer disease.
Neurology 2008;71(9):656-64.
2008: Sleegers K; Brouwers N; Maurer-Stroh S; van Es M A; Van Damme P; van Vught P W J; van der Zee J; Serneels S; De Pooter T; Van den Broeck M; Cruts M; Schymkowitz J; De Jonghe P; Rousseau F; van den Berg L H; Robberecht W; Van Broeckhoven C
Progranulin genetic variability contributes to amyotrophic lateral sclerosis.
Neurology 2008;71(4):253-9.
2008: Sleegers Kristel; Kumar-Singh Samir; Cruts Marc; Van Broeckhoven Christine
Molecular pathogenesis of frontotemporal lobar degeneration: basic science seminar in neurology.
Archives of neurology 2008;65(6):700-4.
2008: Bogaerts Veerle; Nuytemans Karen; Reumers Joke; Pals Philippe; Engelborghs Sebastiaan; Pickut Barbara; Corsmit Ellen; Peeters Karin; Schymkowitz Joost; De Deyn Peter Paul; Cras Patrick; Rousseau Frederic; Theuns Jessie; Van Broeckhoven Christine
Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease.
Human mutation 2008;29(6):832-40.
2008: Bettens Karolien; Brouwers Nathalie; Engelborghs Sebastiaan; De Deyn Peter P; Van Broeckhoven Christine; Sleegers Kristel
SORL1 is genetically associated with increased risk for late-onset Alzheimer disease in the Belgian population.
Human mutation 2008;29(5):769-70.
2008: Arias-Vásquez Alejandro; Aulchenko Yurii S; Isaacs Aaron; van Oosterhout Andy; Sleegers Kristels; Hofman Albert; van Broeckhoven Christine; Oostra Ben A; Breteler Monique; van Duijn Cornelia M
Cyclin-dependent kinase 5 is associated with risk for Alzheimer's disease in a Dutch population-based study.
Journal of neurology 2008;255(5):655-62.
2008: Haugarvoll K; Rademakers R; Kachergus J M; Nuytemans K; Ross O A; Gibson J M; Tan E-K; Gaig C; Tolosa E; Goldwurm S; Guidi M; Riboldazzi G; Brown L; Walter U; Benecke R; Berg D; Gasser T; Theuns J; Pals P; Cras P; De Deyn P Paul; Engelborghs S; Pickut B; Uitti R J; Foroud T; Nichols W C; Hagenah J; Klein C; Samii A; Zabetian C P; Bonifati V; Van Broeckhoven C; Farrer M J; Wszolek Z K
Lrrk2 R1441C parkinsonism is clinically similar to sporadic Parkinson disease.
Neurology 2008;70(16 Pt 2):1456-60.
2008: Cruts Marc; Van Broeckhoven Christine
Loss of progranulin function in frontotemporal lobar degeneration.
Trends in genetics : TIG 2008;24(4):186-94.
2008: Nuytemans Karen; Rademakers Rosa; Theuns Jessie; Pals Philippe; Engelborghs Sebastiaan; Pickut Barbara; de Pooter Tim; Peeters Karin; Mattheijssens Maria; Van den Broeck Marleen; Cras Patrick; De Deyn Peter Paul; van Broeckhoven Christine
Founder mutation p.R1441C in the leucine-rich repeat kinase 2 gene in Belgian Parkinson's disease patients.
European journal of human genetics : EJHG 2008;16(4):471-9.
2008: Rüb U; Brunt E R; Seidel K; Gierga K; Mooy C M; Kettner M; Van Broeckhoven C; Bechmann I; La Spada A R; Schöls L; den Dunnen W; de Vos R A I; Deller T
Spinocerebellar ataxia type 7 (SCA7): widespread brain damage in an adult-onset patient with progressive visual impairments in comparison with an adult-onset patient without visual impairments.
Neuropathology and applied neurobiology 2008;34(2):155-68.
2008: Venken T; Alaerts M; Souery D; Goossens D; Sluijs S; Navon R; Van Broeckhoven C; Mendlewicz J; Del-Favero J; Claes S
Chromosome 10q harbors a susceptibility locus for bipolar disorder in Ashkenazi Jewish families.
Molecular psychiatry 2008;13(4):442-50.
2008: Le Ber Isabelle; Camuzat Agnès; Hannequin Didier; Pasquier Florence; Guedj Eric; Rovelet-Lecrux Anne; Hahn-Barma Valérie; van der Zee Julie; Clot Fabienne; Bakchine Serge; Puel Michèle; Ghanim Mustapha; Lacomblez Lucette; Mikol Jacqueline; Deramecourt Vincent; Lejeune Pascal; de la Sayette Vincent; Belliard Serge; Vercelletto Martine; Meyrignac Christian; Van Broeckhoven Christine; Lambert Jean-Charles; Verpillat Patrice; Campion Dominique; Habert Marie-Odile; Dubois Bruno; Brice Alexis;
Phenotype variability in progranulin mutation carriers: a clinical, neuropsychological, imaging and genetic study.
Brain : a journal of neurology 2008;131(Pt 3):732-46.
2008: Bogaerts V; Theuns J; van Broeckhoven C
Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?
Genes, brain, and behavior 2008;7(2):129-51.
2008: Van Broeck Bianca; Vanhoutte Greet; Pirici Daniel; Van Dam Debby; Wils Hans; Cuijt Ivy; Vennekens Krist'l; Zabielski Monika; Michalik Andrej; Theuns Jessie; De Deyn Peter Paul; Van der Linden Annemie; Van Broeckhoven Christine; Kumar-Singh Samir
Intraneuronal amyloid beta and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease.
Neurobiology of aging 2008;29(2):241-52.
2008: Theuns Jessie; Van Broeckhoven Christine
alpha-Synuclein gene duplications in sporadic Parkinson disease.
Neurology 2008;70(1):7-9.
2008: Gijselinck I; van der Zee J; Engelborghs S; Goossens D; Peeters K; Mattheijssens M; Corsmit E; Del-Favero J; De Deyn P P; Van Broeckhoven C; Cruts M
Progranulin locus deletion in frontotemporal dementia.
Human mutation 2008;29(1):53-8.
2008: van Es Michael A; van Vught Paul W J; Blauw Hylke M; Franke Lude; Saris Christiaan G J; Van den Bosch Ludo; de Jong Sonja W; de Jong Vianney; Baas Frank; van't Slot Ruben; Lemmens Robin; Schelhaas Helenius J; Birve Anna; Sleegers Kristel; Van Broeckhoven Christine; Schymick Jennifer C; Traynor Bryan J; Wokke John H J; Wijmenga Cisca; Robberecht Wim; Andersen Peter M; Veldink Jan H; Ophoff Roel A; van den Berg Leonard H
Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis.
Nature genetics 2008;40(1):29-31.
2008: van der Zee Julie; Urwin Hazel; Engelborghs Sebastiaan; Bruyland Marc; Vandenberghe Rik; Dermaut Bart; De Pooter Tim; Peeters Karin; Santens Patrick; De Deyn Peter P; Fisher Elizabeth M; Collinge John; Isaacs Adrian M; Van Broeckhoven Christine
CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro.
Human molecular genetics 2008;17(2):313-22.
2008: Ramakers I H G B; Visser P J; Aalten P; Bekers O; Sleegers K; van Broeckhoven C L; Jolles J; Verhey F R J
The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology.
Dementia and geriatric cognitive disorders 2008;26(2):101-8.
2008: Brouwers Nathalie; Sleegers Kristel; Van Broeckhoven Christine
Molecular genetics of Alzheimer's disease: an update.
Annals of medicine 2008;40(8):562-83.
2008: Persson J; Lind J; Larsson A; Ingvar M; Sleegers K; Van Broeckhoven C; Adolfsson R; Nilsson L-G; Nyberg L
Altered deactivation in individuals with genetic risk for Alzheimer's disease.
Neuropsychologia 2008;46(6):1679-87.
2007: Lyle Robert; Prandini Paola; Osoegawa Kazutoyo; ten Hallers Boudewijn; Humphray Sean; Zhu Baoli; Eyras Eduardo; Castelo Robert; Bird Christine P; Gagos Sarantos; Scott Carol; Cox Antony; Deutsch Samuel; Ucla Catherine; Cruts Marc; Dahoun Sophie; She Xinwei; Bena Frederique; Wang Sheng-Yue; Van Broeckhoven Christine; Eichler Evan E; Guigo Roderic; Rogers Jane; de Jong Pieter J; Reymond Alexandre; Antonarakis Stylianos E
Islands of euchromatin-like sequence and expressed polymorphic sequences within the short arm of human chromosome 21.
Genome research 2007;17(11):1690-6.
2007: Brouwers Nathalie; Nuytemans Karen; van der Zee Julie; Gijselinck Ilse; Engelborghs Sebastiaan; Theuns Jessie; Kumar-Singh Samir; Pickut Barbara A; Pals Philippe; Dermaut Bart; Bogaerts Veerle; De Pooter Tim; Serneels Sally; Van den Broeck Marleen; Cuijt Ivy; Mattheijssens Maria; Peeters Karin; Sciot Raf; Martin Jean-Jacques; Cras Patrick; Santens Patrick; Vandenberghe Rik; De Deyn Peter P; Cruts Marc; Van Broeckhoven Christine; Sleegers Kristel
Alzheimer and Parkinson diagnoses in progranulin null mutation carriers in an extended founder family.
Archives of neurology 2007;64(10):1436-46.
2007: van Es Michael A; Van Vught Paul W; Blauw Hylke M; Franke Lude; Saris Christiaan G; Andersen Peter M; Van Den Bosch Ludo; de Jong Sonja W; van 't Slot Ruben; Birve Anna; Lemmens Robin; de Jong Vianney; Baas Frank; Schelhaas Helenius J; Sleegers Kristel; Van Broeckhoven Christine; Wokke John H J; Wijmenga Cisca; Robberecht Wim; Veldink Jan H; Ophoff Roel A; van den Berg Leonard H
ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study.
Lancet neurology 2007;6(10):869-77.
2007: Van Den Eede Filip; Venken Tine; Van Den Bogaert Ann; Del-Favero Jurgen; Norrback Karl-Fredrik; Nilsson Lars Göran; Adolfsson Rolf; Van Broeckhoven Christine; Claes Stephan J
Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in bipolar disorder.
Psychiatric genetics 2007;17(5):304-7.
2007: Sundström A; Nilsson L-G; Cruts M; Adolfsson R; Van Broeckhoven C; Nyberg L
Fatigue before and after mild traumatic brain injury: pre-post-injury comparisons in relation to Apolipoprotein E.
Brain injury : [BI] 2007;21(10):1049-54.
2007: Massat I; Lerer B; Souery D; Blackwood D; Muir W; Kaneva R; Nöthen M M; Oruc L; Papadimitriou G N; Dikeos D; Serretti A; Bellivier F; Golmard J L; Milanova V; Del-Favero J; Van Broeckhoven C; Mendlewicz J
HTR2C (cys23ser) polymorphism influences early onset in bipolar patients in a large European multicenter association study.
Molecular psychiatry 2007;12(9):797-8.
2007: Bogaerts Veerle; Engelborghs Sebastiaan; Kumar-Singh Samir; Goossens Dirk; Pickut Barbara; van der Zee Julie; Sleegers Kristel; Peeters Karin; Martin Jean-Jacques; Del-Favero Jurgen; Gasser Thomas; Dickson Dennis W; Wszolek Zbigniew K; De Deyn Peter P; Theuns Jessie; Van Broeckhoven Christine
A novel locus for dementia with Lewy bodies: a clinically and genetically heterogeneous disorder.
Brain : a journal of neurology 2007;130(Pt 9):2277-91.
2007: Van Den Eede Filip; Venken Tine; Del-Favero Jurgen; Norrback Karl-Fredrik; Souery Daniel; Nilsson Lars Göran; Van den Bossche Bart; Hulstijn Wouter; Sabbe Bernard G C; Cosyns Paul; Mendlewicz Julien; Adolfsson Rolf; Van Broeckhoven Christine; Claes Stephan J
Single nucleotide polymorphism analysis of corticotropin-releasing factor-binding protein gene in recurrent major depressive disorder.
Psychiatry research 2007;153(1):17-25.
2007: Engelborghs Sebastiaan; Sleegers Kristel; Cras Patrick; Brouwers Nathalie; Serneels Sally; De Leenheir Evelyn; Martin Jean-Jacques; Vanmechelen Eugeen; Van Broeckhoven Christine; De Deyn Peter Paul
No association of CSF biomarkers with APOEepsilon4, plaque and tangle burden in definite Alzheimer's disease.
Brain : a journal of neurology 2007;130(Pt 9):2320-6.
2007: Le Ber Isabelle; van der Zee Julie; Hannequin Didier; Gijselinck Ilse; Campion Dominique; Puel Michèle; Laquerrière Annie; De Pooter Tim; Camuzat Agnès; Van den Broeck Marleen; Dubois Bruno; Sellal François; Lacomblez Lucette; Vercelletto Martine; Thomas-Antérion Catherine; Michel Bernard-François; Golfier Véronique; Didic Mira; Salachas François; Duyckaerts Charles; Cruts Marc; Verpillat Patrice; Van Broeckhoven Christine; Brice Alexis;
Progranulin null mutations in both sporadic and familial frontotemporal dementia.
Human mutation 2007;28(9):846-55.
2007: Dierick Ines; Irobi Joy; Janssens Sophie; Theuns Jessie; Lemmens Robin; Jacobs An; Corsmit Ellen; Hersmus Nicole; Van Den Bosch Ludo; Robberecht Wim; De Jonghe Peter; Van Broeckhoven Christine; Timmerman Vincent
Genetic variant in the HSPB1 promoter region impairs the HSP27 stress response.
Human mutation 2007;28(8):830.
2007: Wollmer M Axel; Sleegers Kristel; Ingelsson Martin; Zekanowski Cezary; Brouwers Nathalie; Maruszak Aleksandra; Brunner Fabienne; Huynh Kim-Dung; Kilander Lena; Brundin Rose-Marie; Hedlund Marie; Giedraitis Vilmantas; Glaser Anna; Engelborghs Sebastiaan; De Deyn Peter P; Kapaki Elisabeth; Tsolaki Magdalini; Daniilidou Makrina; Molyva Dimitra; Paraskevas George P; Thal Dietmar R; Barcikowska Maria; Kuznicki Jacek; Lannfelt Lars; Van Broeckhoven Christine; Nitsch Roger M; Hock Christoph; Papassotiropoulos Andreas
Association study of cholesterol-related genes in Alzheimer's disease.
Neurogenetics 2007;8(3):179-88.
2007: Liu Fan; Arias-Vásquez Alejandro; Sleegers Kristel; Aulchenko Yurii S; Kayser Manfred; Sanchez-Juan Pascual; Feng Bing-Jian; Bertoli-Avella Aida M; van Swieten John; Axenovich Tatiana I; Heutink Peter; van Broeckhoven Christine; Oostra Ben A; van Duijn Cornelia M
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population.
American journal of human genetics 2007;81(1):17-31.
2007: van der Zee Julie; Le Ber Isabelle; Maurer-Stroh Sebastian; Engelborghs Sebastiaan; Gijselinck Ilse; Camuzat Agnès; Brouwers Nathalie; Vandenberghe Rik; Sleegers Kristel; Hannequin Didier; Dermaut Bart; Schymkowitz Joost; Campion Dominique; Santens Patrick; Martin Jean-Jacques; Lacomblez Lucette; De Pooter Tim; Peeters Karin; Mattheijssens Maria; Vercelletto Martine; Van den Broeck Marleen; Cruts Marc; De Deyn Peter P; Rousseau Frederic; Brice Alexis; Van Broeckhoven Christine
Mutations other than null mutations producing a pathogenic loss of progranulin in frontotemporal dementia.
Human mutation 2007;28(4):416.
2007: de Frias Cindy M; Bunce David; Wahlin Ake; Adolfsson Rolf; Sleegers Kristel; Cruts Marc; Van Broeckhoven Christine; Nilsson Lars-Göran
Cholesterol and triglycerides moderate the effect of apolipoprotein E on memory functioning in older adults.
The journals of gerontology. Series B, Psychological sciences and social sciences 2007;62(2):P112-8.
2007: Sundström A; Nilsson L-G; Cruts M; Adolfsson R; Van Broeckhoven C; Nyberg L
Increased risk of dementia following mild head injury for carriers but not for non-carriers of the APOE epsilon4 allele.
International psychogeriatrics / IPA 2007;19(1):159-65.
2007: Kumar-Singh Samir; Van Broeckhoven Christine
Frontotemporal lobar degeneration: current concepts in the light of recent advances.
Brain pathology (Zurich, Switzerland) 2007;17(1):104-14.
2007: Weckx Stefan; De Rijk Peter; Glassee Wim; Van Broeckhoven Christine; Del-Favero Jurgen
SNPbox: web-based high-throughput primer design with an eye for repetitive sequences.
Methods in molecular biology (Clifton, N.J.) 2007;402():179-200.
2007: Van Broeck Bianca; Van Broeckhoven Christine; Kumar-Singh Samir
Current insights into molecular mechanisms of Alzheimer disease and their implications for therapeutic approaches.
Neuro-degenerative diseases 2007;4(5):349-65.
2007: van der Zee Julie; Gijselinck Ilse; Pirici Daniel; Kumar-Singh Samir; Cruts Marc; Van Broeckhoven Christine
Frontotemporal lobar degeneration with ubiquitin-positive inclusions: a molecular genetic update.
Neuro-degenerative diseases 2007;4(2-3):227-35.
2006: Cruts Marc; Kumar-Singh Samir; Van Broeckhoven Christine
Progranulin mutations in ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.
Current Alzheimer research 2006;3(5):485-91.
2006: Rüb U; Brunt E R; Petrasch-Parwez E; Schöls L; Theegarten D; Auburger G; Seidel K; Schultz C; Gierga K; Paulson H; van Broeckhoven C; Deller T; de Vos R A I
Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7.
Neuropathology and applied neurobiology 2006;32(6):635-49.
2006: Van Den Eede Filip; van West Dirk; Van Broeckhoven Christine; Claes Stephan J
Role of glucocorticoid receptor gene in vulnerability for major depression: commentary on Neigh and Nemeroff.
Trends in endocrinology and metabolism: TEM 2006;17(10):386; author reply 387.
2006: Elbaz Alexis; Nelson Lorene M; Payami Haydeh; Ioannidis John P A; Fiske Brian K; Annesi Grazia; Carmine Belin Andrea; Factor Stewart A; Ferrarese Carlo; Hadjigeorgiou Georgios M; Higgins Donald S; Kawakami Hideshi; Krüger Rejko; Marder Karen S; Mayeux Richard P; Mellick George D; Nutt John G; Ritz Beate; Samii Ali; Tanner Caroline M; Van Broeckhoven Christine; Van Den Eeden Stephen K; Wirdefeldt Karin; Zabetian Cyrus P; Dehem Marie; Montimurro Jennifer S; Southwick Audrey; Myers Richard M; Trikalinos Thomas A
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study.
Lancet neurology 2006;5(11):917-23.
2006: Lind Johanna; Ingvar Martin; Persson Jonas; Sleegers Kristel; Van Broeckhoven Christine; Adolfsson Rolf; Nilsson Lars-Göran; Nyberg Lars
Parietal cortex activation predicts memory decline in apolipoprotein E-epsilon4 carriers.
Neuroreport 2006;17(16):1683-6.
2006: Brouwers Nathalie; Sleegers Kristel; Engelborghs Sebastiaan; Bogaerts Veerle; Serneels Sally; Kamali Kenan; Corsmit Ellen; De Leenheir Evelyn; Martin Jean-Jacques; De Deyn Peter P; Van Broeckhoven Christine; Theuns Jessie
Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease.
Brain : a journal of neurology 2006;129(Pt 11):2984-91.
2006: Sleegers Kristel; Brouwers Nathalie; Gijselinck Ilse; Theuns Jessie; Goossens Dirk; Wauters Jan; Del-Favero Jurgen; Cruts Marc; van Duijn Cornelia M; Van Broeckhoven Christine
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy.
Brain : a journal of neurology 2006;129(Pt 11):2977-83.
2006: Van Den Bogaert Ann; Sleegers Kristel; De Zutter Sonia; Heyrman Lien; Norrback Karl-Fredrik; Adolfsson Rolf; Van Broeckhoven Christine; Del-Favero Jurgen
Association of brain-specific tryptophan hydroxylase, TPH2, with unipolar and bipolar disorder in a Northern Swedish, isolated population.
Archives of general psychiatry 2006;63(10):1103-10.
2006: Van Den Bogaert Ann; Sleegers Kristel; De Zutter Sonia; Heyrman Lien; Norrback Karl-Fredrik; Adolfsson Rolf; Van Broeckhoven Christine; Del-Favero Jurgen
No allelic association or interaction of three known functional polymorphisms with bipolar disorder in a northern Swedish isolated population.
Psychiatric genetics 2006;16(5):209-12.
2006: Gijselinck Ilse; Bogaerts Veerle; Rademakers Rosa; van der Zee Julie; Van Broeckhoven Christine; Cruts Marc
Visualization of MAPT inversion on stretched chromosomes of tau-negative frontotemporal dementia patients.
Human mutation 2006;27(10):1057-9.
2006: Theuns J; Marjaux E; Vandenbulcke M; Van Laere K; Kumar-Singh S; Bormans G; Brouwers N; Van den Broeck M; Vennekens K; Corsmit E; Cruts M; De Strooper B; Van Broeckhoven C; Vandenberghe R
Alzheimer dementia caused by a novel mutation located in the APP C-terminal intracytosolic fragment.
Human mutation 2006;27(9):888-96.
2006: Van Den Bogaert Ann; Del-Favero Jurgen; Van Broeckhoven Christine
Major affective disorders and schizophrenia: a common molecular signature?
Human mutation 2006;27(9):833-53.
2006: Audenaert D; Schwartz E; Claeys K G; Claes L; Deprez L; Suls A; Van Dyck T; Lagae L; Van Broeckhoven C; Macdonald R L; De Jonghe P
A novel GABRG2 mutation associated with febrile seizures.
Neurology 2006;67(4):687-90.
2006: Maraganore Demetrius M; de Andrade Mariza; Elbaz Alexis; Farrer Matthew J; Ioannidis John P; Krüger Rejko; Rocca Walter A; Schneider Nicole K; Lesnick Timothy G; Lincoln Sarah J; Hulihan Mary M; Aasly Jan O; Ashizawa Tetsuo; Chartier-Harlin Marie-Christine; Checkoway Harvey; Ferrarese Carlo; Hadjigeorgiou Georgios; Hattori Nobutaka; Kawakami Hideshi; Lambert Jean-Charles; Lynch Timothy; Mellick George D; Papapetropoulos Spiridon; Parsian Abbas; Quattrone Aldo; Riess Olaf; Tan Eng-King; Van Broeckhoven Christine;
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease.
JAMA : the journal of the American Medical Association 2006;296(6):661-70.
2006: Cruts Marc; Gijselinck Ilse; van der Zee Julie; Engelborghs Sebastiaan; Wils Hans; Pirici Daniel; Rademakers Rosa; Vandenberghe Rik; Dermaut Bart; Martin Jean-Jacques; van Duijn Cornelia; Peeters Karin; Sciot Raf; Santens Patrick; De Pooter Tim; Mattheijssens Maria; Van den Broeck Marleen; Cuijt Ivy; Vennekens Krist'l; De Deyn Peter P; Kumar-Singh Samir; Van Broeckhoven Christine
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.
Nature 2006;442(7105):920-4.
2006: Dikeos Dimitris G; Papadimitriou George N; Souery Daniel; Del-Favero Jurgen; Massat Isabelle; Blackwood Douglas; Cichon Sven; Daskalopoulou Eugenia; Ivezic Sladjana; Kaneva Radka; Karadima Georgia; Lorenzi Cristina; Milanova Vihra; Muir Walter; Nöthen Markus; Oruc Lilijana; Rietschel Marcella; Serretti Alessandro; Van Broeckhoven Christine; Soldatos Constantin R; Stefanis Costas N; Mendlewicz Julien
Lack of genetic association between the phospholipase A2 gene and bipolar mood disorder in a European multicentre case-control study.
Psychiatric genetics 2006;16(4):169-71.
2006: Kumar-Singh Samir; Theuns Jessie; Van Broeck Bianca; Pirici Daniel; Vennekens Krist'l; Corsmit Ellen; Cruts Marc; Dermaut Bart; Wang Rong; Van Broeckhoven Christine
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40.
Human mutation 2006;27(7):686-95.
2006: Theuns Jessie; Brouwers Nathalie; Engelborghs Sebastiaan; Sleegers Kristel; Bogaerts Veerle; Corsmit Ellen; De Pooter Tim; van Duijn Cornelia M; De Deyn Peter P; Van Broeckhoven Christine
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.
American journal of human genetics 2006;78(6):936-46.
2006: Audenaert Dominique; Van Broeckhoven Christine; De Jonghe Peter
Genes and loci involved in febrile seizures and related epilepsy syndromes.
Human mutation 2006;27(5):391-401.
2006: Lind Johanna; Persson Jonas; Ingvar Martin; Larsson Anne; Cruts Marc; Van Broeckhoven Christine; Adolfsson Rolf; Bäckman Lars; Nilsson Lars-Göran; Petersson Karl Magnus; Nyberg Lars
Reduced functional brain activity response in cognitively intact apolipoprotein E epsilon4 carriers.
Brain : a journal of neurology 2006;129(Pt 5):1240-8.
2006: Al-Yahyaee S; Al-Gazali L I; De Jonghe P; Al-Barwany H; Al-Kindi M; De Vriendt E; Chand P; Koul R; Jacob P C; Gururaj A; Sztriha L; Parrado A; Van Broeckhoven C; Bayoumi R A
A novel locus for hereditary spastic paraplegia with thin corpus callosum and epilepsy.
Neurology 2006;66(8):1230-4.
2006: Persson J; Lind J; Larsson A; Ingvar M; Cruts M; Van Broeckhoven C; Adolfsson R; Nilsson L-G; Nyberg L
Altered brain white matter integrity in healthy carriers of the APOE epsilon4 allele: a risk for AD?
Neurology 2006;66(7):1029-33.
2006: van der Zee Julie; Rademakers Rosa; Engelborghs Sebastiaan; Gijselinck Ilse; Bogaerts Veerle; Vandenberghe Rik; Santens Patrick; Caekebeke Jo; De Pooter Tim; Peeters Karin; Lübke Ursula; Van den Broeck Marleen; Martin Jean-Jacques; Cruts Marc; De Deyn Peter P; Van Broeckhoven Christine; Dermaut Bart
A Belgian ancestral haplotype harbours a highly prevalent mutation for 17q21-linked tau-negative FTLD.
Brain : a journal of neurology 2006;129(Pt 4):841-52.
2006: Pirici Daniel; Vandenberghe Rik; Rademakers Rosa; Dermaut Bart; Cruts Marc; Vennekens Krist'l; Cuijt Ivy; Lübke Ursula; Ceuterick Chantal; Martin Jean-Jacques; Van Broeckhoven Christine; Kumar-Singh Samir
Characterization of ubiquitinated intraneuronal inclusions in a novel Belgian frontotemporal lobar degeneration family.
Journal of neuropathology and experimental neurology 2006;65(3):289-301.
2006: Lind Johanna; Larsson Anne; Persson Jonas; Ingvar Martin; Nilsson Lars-Göran; Bäckman Lars; Adolfsson Rolf; Cruts Marc; Sleegers Kristel; Van Broeckhoven Christine; Nyberg Lars
Reduced hippocampal volume in non-demented carriers of the apolipoprotein E epsilon4: relation to chronological age and recognition memory.
Neuroscience letters 2006;396(1):23-7.
2006: van West Dirk; Van Den Eede Filip; Del-Favero Jurgen; Souery Daniel; Norrback Karl-Fredrik; Van Duijn Cornelia; Sluijs Sam; Adolfsson Rolf; Mendlewicz Julien; Deboutte Dirk; Van Broeckhoven Christine; Claes Stephan
Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2006;31(3):620-7.
2006: Engelborghs Sebastiaan; Dermaut Bart; Mariën Peter; Symons Anoek; Vloeberghs Ellen; Maertens Karen; Somers Nore; Goeman Johan; Rademakers Rosa; Van den Broeck Marleen; Pickut Barbara; Cruts Marc; Van Broeckhoven Christine; De Deyn Peter P
Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia.
Neurobiology of aging 2006;27(2):285-92.
2006: Venken Tine; Alaerts Maaike; Adolfsson Rolf; Broeckhoven Christine Van; Del-Favero Jurgen
No association of the trace amine-associated receptor 6 with bipolar disorder in a northern Swedish population.
Psychiatric genetics 2006;16(1):1-2.
2006: van Leeuwen F W; van Tijn P; Sonnemans M A F; Hobo B; Mann D M A; Van Broeckhoven C; Kumar-Singh S; Cras P; Leuba G; Savioz A; Maat-Schieman M L C; Yamaguchi H; Kros J M; Kamphorst W; Hol E M; de Vos R A I; Fischer D F
Frameshift proteins in autosomal dominant forms of Alzheimer disease and other tauopathies.
Neurology 2006;66(2 Suppl 1):S86-92.
2006: Deprez Liesbet; Claes Lieve R F; Claeys Kristl G; Audenaert Dominique; Van Dyck Tine; Goossens Dirk; Van Paesschen Wim; Del-Favero Jurgen; Van Broeckhoven Christine; De Jonghe Peter
Genome-wide linkage of febrile seizures and epilepsy to the FEB4 locus at 5q14.3-q23.1 and no MASS1 mutation.
Human genetics 2006;118(5):618-25.
2006: Brouwers Nathalie; Sleegers Kristel; Engelborghs Sebastiaan; Bogaerts Veerle; van Duijn Cornelia M; De Deyn Peter Paul; Van Broeckhoven Christine; Dermaut Bart
The UBQLN1 polymorphism, UBQ-8i, at 9q22 is not associated with Alzheimer's disease with onset before 70 years.
Neuroscience letters 2006;392(1-2):72-4.
2006: Van Broeckhoven Christine; Kumar-Singh Samir
Genetics and pathology of alpha-secretase site AbetaPP mutations in the understanding of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):389-98.
2005: Van Den Bogaert Ann; De Zutter Sonia; Heyrman Lien; Mendlewicz Julien; Adolfsson Rolf; Van Broeckhoven Christine; Del-Favero Jurgen
Response to Zhang et al (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major Depression. Neuron 45, 11-16.
Neuron 2005;48(5):704; author reply 705-6.
2005: Dermaut Bart; Kumar-Singh Samir; Rademakers Rosa; Theuns Jessie; Cruts Marc; Van Broeckhoven Christine
Tau is central in the genetic Alzheimer-frontotemporal dementia spectrum.
Trends in genetics : TIG 2005;21(12):664-72.
2005: Mendlewicz Julien; Oswald Pierre; Claes Stephan; Massat Isabelle; Souery Daniel; Van Broeckhoven Christine; Del-Favero Jurgen
Patient-control association study of substance P-related genes in unipolar and bipolar affective disorders.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2005;8(4):505-13.
2005: Audenaert D; Claes L; Claeys K G; Deprez L; Van Dyck T; Goossens D; Del-Favero J; Van Paesschen W; Van Broeckhoven C; De Jonghe P
A novel susceptibility locus at 2p24 for generalised epilepsy with febrile seizures plus.
Journal of medical genetics 2005;42(12):947-52.
2005: Rademakers Rosa; Melquist Stacey; Cruts Marc; Theuns Jessie; Del-Favero Jurgen; Poorkaj Parvoneh; Baker Matt; Sleegers Kristel; Crook Richard; De Pooter Tim; Bel Kacem Samira; Adamson Jennifer; Van den Bossche Dirk; Van den Broeck Marleen; Gass Jennifer; Corsmit Ellen; De Rijk Peter; Thomas Natalie; Engelborghs Sebastiaan; Heckman Michael; Litvan Irene; Crook Julia; De Deyn Peter P; Dickson Dennis; Schellenberg Gerard D; Van Broeckhoven Christine; Hutton Michael L
High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy.
Human molecular genetics 2005;14(21):3281-92.
2005: Kuhlenbäumer Gregor; Hannibal Mark C; Nelis Eva; Schirmacher Anja; Verpoorten Nathalie; Meuleman Jan; Watts Giles D J; De Vriendt Els; Young Peter; Stögbauer Florian; Halfter Hartmut; Irobi Joy; Goossens Dirk; Del-Favero Jurgen; Betz Benjamin G; Hor Hyun; Kurlemann Gert; Bird Thomas D; Airaksinen Eila; Mononen Tarja; Serradell Adolfo Pou; Prats José M; Van Broeckhoven Christine; De Jonghe Peter; Timmerman Vincent; Ringelstein E Bernd; Chance Phillip F
Mutations in SEPT9 cause hereditary neuralgic amyotrophy.
Nature genetics 2005;37(10):1044-6.
2005: Rademakers Rosa; Cruts Marc; Sleegers Kristel; Dermaut Bart; Theuns Jessie; Aulchenko Yurii; Weckx Stefan; De Pooter Tim; Van den Broeck Marleen; Corsmit Ellen; De Rijk Peter; Del-Favero Jurgen; van Swieten John; van Duijn Cornelia M; Van Broeckhoven Christine
Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample.
American journal of human genetics 2005;77(4):643-52.
2005: Papadimitriou G N; Souery D; Lipp O; Massat I; Mahieu B; Van Broeckhoven C; Mendlewicz J
In search of anticipation in unipolar affective disorder.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(5):511-6.
2005: Oswald Pierre; Del-Favero Jurgen; Massat Isabelle; Souery Daniel; Claes Stephan; Van Broeckhoven Christine; Mendlewicz Julien
No implication of brain-derived neurotrophic factor (BDNF) gene in unipolar affective disorder: evidence from Belgian first and replication patient-control studies.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(5):491-5.
2005: Kumar-Singh Samir; Pirici Daniel; McGowan Eileen; Serneels Sally; Ceuterick Chantal; Hardy John; Duff Karen; Dickson Dennis; Van Broeckhoven Christine
Dense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls.
The American journal of pathology 2005;167(2):527-43.
2005: Rademakers R; Sleegers K; Theuns J; Van den Broeck M; Bel Kacem S; Nilsson L-G; Adolfsson R; van Duijn C M; Van Broeckhoven C; Cruts M
Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease.
Neurobiology of aging 2005;26(8):1145-51.
2005: Cruts Marc; Rademakers Rosa; Gijselinck Ilse; van der Zee Julie; Dermaut Bart; de Pooter Tim; de Rijk Peter; Del-Favero Jurgen; van Broeckhoven Christine
Genomic architecture of human 17q21 linked to frontotemporal dementia uncovers a highly homologous family of low-copy repeats in the tau region.
Human molecular genetics 2005;14(13):1753-62.
2005: Van Den Eede Filip; Van Broeckhoven Christine; Claes Stephan J
Corticotropin-releasing factor-binding protein, stress and major depression.
Ageing research reviews 2005;4(2):213-39.
2005: López León Sandra; Croes Esther A; Sayed-Tabatabaei Fakhredin A; Claes Stephan; Van Broeckhoven Christine; van Duijn Cornelia M
The dopamine D4 receptor gene 48-base-pair-repeat polymorphism and mood disorders: a meta-analysis.
Biological psychiatry 2005;57(9):999-1003.
2005: Weckx Stefan; Del-Favero Jurgen; Rademakers Rosa; Claes Lieve; Cruts Marc; De Jonghe Peter; Van Broeckhoven Christine; De Rijk Peter
novoSNP, a novel computational tool for sequence variation discovery.
Genome research 2005;15(3):436-42.
2005: Venken Tine; Claes Stephan; Sluijs Samuel; Paterson Andrew D; van Duijn Cornelia; Adolfsson Rolf; Del-Favero Jurgen; Van Broeckhoven Christine
Genomewide scan for affective disorder susceptibility Loci in families of a northern Swedish isolated population.
American journal of human genetics 2005;76(2):237-48.
2005: Weckx Stefan; De Rijk Peter; Van Broeckhoven Christine; Del-Favero Jurgen
SNPbox: a modular software package for large-scale primer design.
Bioinformatics (Oxford, England) 2005;21(3):385-7.
2004: Claes L R F; Ceulemans B; Audenaert D; Deprez L; Jansen A; Hasaerts D; Weckx S; Claeys K G; Del-Favero J; Van Broeckhoven C; De Jonghe P
De novo KCNQ2 mutations in patients with benign neonatal seizures.
Neurology 2004;63(11):2155-8.
2004: van der Cammen Tischa J M; Croes Esther A; Dermaut Bart; de Jager Marie-Claire; Cruts Marc; Van Broeckhoven Christine; van Duijn Cornelia M
Genetic testing has no place as a routine diagnostic test in sporadic and familial cases of Alzheimer's disease.
Journal of the American Geriatrics Society 2004;52(12):2110-3.
2004: Van Goethem G; Luoma P; Rantamäki M; Al Memar A; Kaakkola S; Hackman P; Krahe R; Löfgren A; Martin J J; De Jonghe P; Suomalainen A; Udd B; Van Broeckhoven C
POLG mutations in neurodegenerative disorders with ataxia but no muscle involvement.
Neurology 2004;63(7):1251-7.
2004: Pals Philippe; Lincoln Sarah; Manning Jonathan; Heckman Michael; Skipper Lisa; Hulihan Mary; Van den Broeck Marleen; De Pooter Tim; Cras Patrick; Crook Julia; Van Broeckhoven Christine; Farrer Matt J
alpha-Synuclein promoter confers susceptibility to Parkinson's disease.
Annals of neurology 2004;56(4):591-5.
2004: Rademakers R; Cruts M; van Broeckhoven C
The role of tau (MAPT) in frontotemporal dementia and related tauopathies.
Human mutation 2004;24(4):277-95.
2004: Ansorge Olaf; Giunti Paola; Michalik Andrej; Van Broeckhoven Christine; Harding Brian; Wood Nicholas; Scaravilli Francesco
Ataxin-7 aggregation and ubiquitination in infantile SCA7 with 180 CAG repeats.
Annals of neurology 2004;56(3):448-52.
2004: Claes L; Audenaert D; Deprez L; Van Paesschen W; Depondt C; Goossens D; Del-Favero J; Van Broeckhoven C; De Jonghe P
Novel locus on chromosome 12q22-q23.3 responsible for familial temporal lobe epilepsy associated with febrile seizures.
Journal of medical genetics 2004;41(9):710-4.
2004: Oswald Pierre; Del-Favero Jurgen; Massat Isabelle; Souery Daniel; Claes Stephan; Van Broeckhoven Christine; Mendlewicz Julien
Non-replication of the brain-derived neurotrophic factor (BDNF) association in bipolar affective disorder: a Belgian patient-control study.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;129B(1):34-5.
2004: Croes E A; Theuns J; Houwing-Duistermaat J J; Dermaut B; Sleegers K; Roks G; Van den Broeck M; van Harten B; van Swieten J C; Cruts M; Van Broeckhoven C; van Duijn C M
Octapeptide repeat insertions in the prion protein gene and early onset dementia.
Journal of neurology, neurosurgery, and psychiatry 2004;75(8):1166-70.
2004: Helisalmi S; Dermaut B; Hiltunen M; Mannermaa A; Van den Broeck M; Lehtovirta M; Koivisto A M; Iivonen S; Cruts M; Soininen H; Van Broeckhoven C
Possible association of nicastrin polymorphisms and Alzheimer disease in the Finnish population.
Neurology 2004;63(1):173-5.
2004: Weckx Stefan; De Rijk Peter; Van Broeckhoven Christine; Del-Favero Jurgen
SNPbox: web-based high-throughput primer design from gene to genome.
Nucleic acids research 2004;32(Web Server issue):W170-2.
2004: Mendlewicz Julien; Souery Daniel; Del-Favero Jurgen; Massat Isabelle; Lindblad Kerstin; Engström Christer; Van den Bossche Dirk; Adolfsson Rolf; Schalling Martin; Van Broeckhoven Christine
Expanded RED products and loci containing CAG/CTG repeats on chromosome 17 (ERDA1) and chromosome 18 (CTG18.1) in trans-generational pairs with bipolar affective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;128B(1):71-5.
2004: Sleegers K; Roks G; Theuns J; Aulchenko Y S; Rademakers R; Cruts M; van Gool W A; Van Broeckhoven C; Heutink P; Oostra B A; van Swieten J C; van Duijn C M
Familial clustering and genetic risk for dementia in a genetically isolated Dutch population.
Brain : a journal of neurology 2004;127(Pt 7):1641-9.
2004: Weckx Stefan; De Rijk Peter; Van Broeckhoven Christine; Del-Favero Jurgen
SSHSuite: an integrated software package for analysis of large-scale suppression subtractive hybridization data.
BioTechniques 2004;36(6):1043-5.
2004: Kuhlenbäumer G; Lüdemann P; Schirmacher A; De Vriendt E; Hünermund G; Young P; Hund-Georgiadis M; Schuierer G; Möller H; Ringelstein E B; Van Broeckhoven C; Timmerman V; Stögbauer F
Autosomal dominant striatal degeneration (ADSD): clinical description and mapping to 5q13-5q14.
Neurology 2004;62(12):2203-8.
2004: Michalik Andrej; Van Broeckhoven Christine
Proteasome degrades soluble expanded polyglutamine completely and efficiently.
Neurobiology of disease 2004;16(1):202-11.
2004: Sundström A; Marklund P; Nilsson L-G; Cruts M; Adolfsson R; Van Broeckhoven C; Nyberg L
APOE influences on neuropsychological function after mild head injury: within-person comparisons.
Neurology 2004;62(11):1963-6.
2004: Irobi Joy; Van Impe Katrien; Seeman Pavel; Jordanova Albena; Dierick Ines; Verpoorten Nathalie; Michalik Andrej; De Vriendt Els; Jacobs An; Van Gerwen Veerle; Vennekens Krist'l; Mazanec Radim; Tournev Ivailo; Hilton-Jones David; Talbot Kevin; Kremensky Ivo; Van Den Bosch Ludo; Robberecht Wim; Van Vandekerckhove Joël; Van Broeckhoven Christine; Gettemans Jan; De Jonghe Peter; Timmerman Vincent
Hot-spot residue in small heat-shock protein 22 causes distal motor neuropathy.
Nature genetics 2004;36(6):597-601.
2004: Dermaut Bart; Kumar-Singh Samir; Engelborghs Sebastian; Theuns Jessie; Rademakers Rosa; Saerens Jos; Pickut Barbara A; Peeters Karin; van den Broeck Marleen; Vennekens Krist'l; Claes Stephen; Cruts Marc; Cras Patrick; Martin Jean-Jacques; Van Broeckhoven Christine; De Deyn Peter Paul
A novel presenilin 1 mutation associated with Pick's disease but not beta-amyloid plaques.
Annals of neurology 2004;55(5):617-26.
2004: Croes Esther A; Alizadeh Behrooz Z; Bertoli-Avella Aida M; Rademaker Tessa; Vergeer-Drop Jeannette; Dermaut Bart; Houwing-Duistermaat Jeanine J; Wientjens Dorothee P W M; Hofman Albert; Van Broeckhoven Christine; van Duijn Cornelia M
Polymorphisms in the prion protein gene and in the doppel gene increase susceptibility for Creutzfeldt-Jakob disease.
European journal of human genetics : EJHG 2004;12(5):389-94.
2004: Mendlewicz Julien; Massat Isabelle; Souery Daniel; Del-Favero Jurgen; Oruc Lilijana; Nöthen Markus M; Blackwood Douglas; Muir Walter; Battersby Sharon; Lerer Beny; Segman Ronen H; Kaneva Radka; Serretti Alessandro; Lilli Roberta; Lorenzi Christian; Jakovljevic Miro; Ivezic Sladana; Rietschel Marcella; Milanova Vihra; Van Broeckhoven Christine
Serotonin transporter 5HTTLPR polymorphism and affective disorders: no evidence of association in a large European multicenter study.
European journal of human genetics : EJHG 2004;12(5):377-82.
2004: Slooter A J C; Cruts M; Hofman A; Koudstaal P J; van der Kuip D; de Ridder M A J; Witteman J C M; Breteler M M B; Van Broeckhoven C; van Duijn C M
The impact of APOE on myocardial infarction, stroke, and dementia: the Rotterdam Study.
Neurology 2004;62(7):1196-8.
2004: van West D; Del-Favero J; Aulchenko Y; Oswald P; Souery D; Forsgren T; Sluijs S; Bel-Kacem S; Adolfsson R; Mendlewicz J; Van Duijn C; Deboutte D; Van Broeckhoven C; Claes S
A major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression.
Molecular psychiatry 2004;9(3):287-92.
2004: Rademakers R; Van den Broeck M; Sleegers K; van Duijn C; Van Broeckhoven C; Cruts M
Absence of pathogenic mutations in presenilin homologue 2 in a conclusively 17-linked tau-negative dementia family.
Neurogenetics 2004;5(1):79-80.
2004: Michalik A; Martin J-J; Van Broeckhoven C
Spinocerebellar ataxia type 7 associated with pigmentary retinal dystrophy.
European journal of human genetics : EJHG 2004;12(1):2-15.
2004: Wanrooij Sjoerd; Luoma Petri; van Goethem Gert; van Broeckhoven Christine; Suomalainen Anu; Spelbrink Johannes N
Twinkle and POLG defects enhance age-dependent accumulation of mutations in the control region of mtDNA.
Nucleic acids research 2004;32(10):3053-64.
2003: Van Goethem G; Mercelis R; Löfgren A; Seneca S; Ceuterick C; Martin J J; Van Broeckhoven C
Patient homozygous for a recessive POLG mutation presents with features of MERRF.
Neurology 2003;61(12):1811-3.
2003: Bornebroek Marjolijn; De Jonghe Chris; Haan Joost; Kumar-Singh Samir; Younkin Steve; Roos Raymund; Van Broeckhoven Christine
Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): decreased plasma amyloid-beta 42 concentration.
Neurobiology of disease 2003;14(3):619-23.
2003: Papadimitriou George N; Dikeos Dimitris G; Souery Daniel; Del-Favero Jurgen; Massat Isabelle; Avramopoulos Dimitrios; Blairy Sylvie; Cichon Sven; Ivezic Sladjana; Kaneva Radka; Karadima Georgia; Lilli Roberta; Milanova Vihra; Nöthen Markus; Oruc Lilijana; Rietschel Marcella; Serretti Alessandro; Van Broeckhoven Christine; Stefanis Costas N; Mendlewicz Julien
Genetic association between the phospholipase A2 gene and unipolar affective disorder: a multicentre case-control study.
Psychiatric genetics 2003;13(4):211-20.
2003: Cruts Marc; Dermaut Bart; Rademakers Rosa; Van den Broeck Marleen; Stögbauer Florian; Van Broeckhoven Christine
Novel APP mutation V715A associated with presenile Alzheimer's disease in a German family.
Journal of neurology 2003;250(11):1374-5.
2003: Claes Stephan; Villafuerte Sandra; Forsgren Thomas; Sluijs Sam; Del-Favero Jurgen; Adolfsson Rolf; Van Broeckhoven Christine
The corticotropin-releasing hormone binding protein is associated with major depression in a population from Northern Sweden.
Biological psychiatry 2003;54(9):867-72.
2003: Rademakers R; Dermaut B; Peeters K; Cruts M; Heutink P; Goate A; Van Broeckhoven C
Tau (MAPT) mutation Arg406Trp presenting clinically with Alzheimer disease does not share a common founder in Western Europe.
Human mutation 2003;22(5):409-11.
2003: Van Gestel S; Van Broeckhoven C
Genetics of personality: are we making progress?
Molecular psychiatry 2003;8(10):840-52.
2003: Van Agtmael Tom; Forrest Susan M; Del-Favero Jurgen; Van Broeckhoven Christine; Williamson Robert
Parametric and nonparametric genome scan analyses for human handedness.
European journal of human genetics : EJHG 2003;11(10):779-83.
2003: Michalik Andrej; Van Broeckhoven Christine
Pathogenesis of polyglutamine disorders: aggregation revisited.
Human molecular genetics 2003;12 Spec No 2():R173-86.
2003: Oswald Pierre; Souery Daniel; Massat Isabelle; Del-Favero Jurgen; Linotte Sylvie; Papadimitriou George; Dikeos Dimitris; Kaneva Radka; Milanova Vibra; Oruc Lilijana; Ivezic Sladana; Serretti Alessandro; Lilli Roberta; Van Broeckhoven Christine; Mendlewicz Julien
Lack of association between the 5HT2A receptor polymorphism (T102C) and unipolar affective disorder in a multicentric European study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(5):365-8.
2003: Nyabi Omar; Bentahir Mostafa; Horré Katrien; Herreman An; Gottardi-Littell Numa; Van Broeckhoven Christine; Merchiers Pascal; Spittaels Kurt; Annaert Wim; De Strooper Bart
Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin.
The Journal of biological chemistry 2003;278(44):43430-6.
2003: Audenaert D; Claes L; Ceulemans B; Löfgren A; Van Broeckhoven C; De Jonghe P
A deletion in SCN1B is associated with febrile seizures and early-onset absence epilepsy.
Neurology 2003;61(6):854-6.
2003: Croes Esther A; Dermaut Bart; Houwing-Duistermaat Jeanine J; Van den Broeck Marleen; Cruts Marc; Breteler Monique M B; Hofman Albert; van Broeckhoven Christine; van Duijn Cornelia M
Early cognitive decline is associated with prion protein codon 129 polymorphism.
Annals of neurology 2003;54(2):275-6.
2003: Engelborghs S; Dermaut B; Goeman J; Saerens J; Mariën P; Pickut B A; Van den Broeck M; Serneels S; Cruts M; Van Broeckhoven C; De Deyn P P
Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects.
Journal of neurology, neurosurgery, and psychiatry 2003;74(8):1148-51.
2003: Van Goethem Gert; Löfgren Ann; Dermaut Bart; Ceuterick Chantal; Martin Jean-Jacques; Van Broeckhoven Christine
Digenic progressive external ophthalmoplegia in a sporadic patient: recessive mutations in POLG and C10orf2/Twinkle.
Human mutation 2003;22(2):175-6.
2003: Lambrechts Diether; Storkebaum Erik; Morimoto Masafumi; Del-Favero Jurgen; Desmet Frederik; Marklund Stefan L; Wyns Sabine; Thijs Vincent; Andersson Jörgen; van Marion Ingrid; Al-Chalabi Ammar; Bornes Stephanie; Musson Rhiannon; Hansen Valerie; Beckman Lars; Adolfsson Rolf; Pall Hardev Singh; Prats Hervé; Vermeire Severine; Rutgeerts Paul; Katayama Shigehiro; Awata Takuya; Leigh Nigel; Lang-Lazdunski Loïc; Dewerchin Mieke; Shaw Christopher; Moons Lieve; Vlietinck Robert; Morrison Karen E; Robberecht Wim; Van Broeckhoven Christine; Collen Désiré; Andersen Peter M; Carmeliet Peter
VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death.
Nature genetics 2003;34(4):383-94.
2003: Johansson C; Willeit M; Levitan R; Partonen T; Smedh C; Del Favero J; Bel Kacem S; Praschak-Rieder N; Neumeister A; Masellis M; Basile V; Zill P; Bondy B; Paunio T; Kasper S; Van Broeckhoven C; Nilsson L G; Lam R; Schalling M; Adolfsson R
The serotonin transporter promoter repeat length polymorphism, seasonal affective disorder and seasonality.
Psychological medicine 2003;33(5):785-92.
2003: Van Goethem Gert; Schwartz Marianne; Löfgren Ann; Dermaut Bart; Van Broeckhoven Christine; Vissing John
Novel POLG mutations in progressive external ophthalmoplegia mimicking mitochondrial neurogastrointestinal encephalomyopathy.
European journal of human genetics : EJHG 2003;11(7):547-9.
2003: Segurado Ricardo; Detera-Wadleigh Sevilla D; Levinson Douglas F; Lewis Cathryn M; Gill Michael; Nurnberger John I; Craddock Nick; DePaulo J Raymond; Baron Miron; Gershon Elliot S; Ekholm Jenny; Cichon Sven; Turecki Gustavo; Claes Stephan; Kelsoe John R; Schofield Peter R; Badenhop Renee F; Morissette J; Coon Hilary; Blackwood Douglas; McInnes L Alison; Foroud Tatiana; Edenberg Howard J; Reich Theodore; Rice John P; Goate Alison; McInnis Melvin G; McMahon Francis J; Badner Judith A; Goldin Lynn R; Bennett Phil; Willour Virginia L; Zandi Peter P; Liu Jianjun; Gilliam Conrad; Juo Suh-Hang; Berrettini Wade H; Yoshikawa Takeo; Peltonen Leena; Lönnqvist Jouko; Nöthen Markus M; Schumacher Johannes; Windemuth Christine; Rietschel Marcella; Propping Peter; Maier Wolfgang; Alda Martin; Grof Paul; Rouleau Guy A; Del-Favero Jurgen; Van Broeckhoven Christine; Mendlewicz Julien; Adolfsson Rolf; Spence M Anne; Luebbert Hermann; Adams Linda J; Donald Jennifer A; Mitchell Philip B; Barden Nicholas; Shink Eric; Byerley William; Muir Walter; Visscher Peter M; Macgregor Stuart; Gurling Hugh; Kalsi Gursharan; McQuillin Andrew; Escamilla Michael A; Reus Victor I; Leon Pedro; Freimer Nelson B; Ewald Henrik; Kruse Torben A; Mors Ole; Radhakrishna Uppala; Blouin Jean-Louis; Antonarakis Stylianos E; Akarsu Nurten
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
American journal of human genetics 2003;73(1):49-62.
2003: Rademakers Rosa; Cruts Marc; Van Broeckhoven Christine
Genetics of early-onset Alzheimer dementia.
TheScientificWorldJournal 2003;3():497-519.
2003: Claes Lieve; Ceulemans Berten; Audenaert Dominique; Smets Katrien; Löfgren Ann; Del-Favero Jurgen; Ala-Mello Sirpa; Basel-Vanagaite Lina; Plecko Barbara; Raskin Salmo; Thiry Paul; Wolf Nicole I; Van Broeckhoven Christine; De Jonghe Peter
De novo SCN1A mutations are a major cause of severe myoclonic epilepsy of infancy.
Human mutation 2003;21(6):615-21.
2003: Theuns Jessie; Remacle Jacques; Killick Richard; Corsmit Ellen; Vennekens Krist'l; Huylebroeck Danny; Cruts Marc; Van Broeckhoven Christine
Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression.
Human molecular genetics 2003;12(8):869-77.
2003: Dermaut Bart; Croes Esther A; Rademakers Rosa; Van den Broeck Marleen; Cruts Marc; Hofman Albert; van Duijn Cornelia M; Van Broeckhoven Christine
PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease.
Annals of neurology 2003;53(3):409-12.
2003: Van Goethem G; Martin J J; Dermaut B; Löfgren A; Wibail A; Ververken D; Tack P; Dehaene I; Van Zandijcke M; Moonen M; Ceuterick C; De Jonghe P; Van Broeckhoven C
Recessive POLG mutations presenting with sensory and ataxic neuropathy in compound heterozygote patients with progressive external ophthalmoplegia.
Neuromuscular disorders : NMD 2003;13(2):133-42.
2003: Goossens D; Van Gestel S; Claes S; De Rijk P; Souery D; Massat I; Van den Bossche D; Backhovens H; Mendlewicz J; Van Broeckhoven C; Del-Favero J
A novel CpG-associated brain-expressed candidate gene for chromosome 18q-linked bipolar disorder.
Molecular psychiatry 2003;8(1):83-9.
2003: Van Goethem Gert; Martin Jean-Jacques; Van Broeckhoven Christine
Progressive external ophthalmoplegia characterized by multiple deletions of mitochondrial DNA: unraveling the pathogenesis of human mitochondrial DNA instability and the initiation of a genetic classification.
Neuromolecular medicine 2003;3(3):129-46.
2002: Nelis E; Erdem S; Van Den Bergh P Y K; Belpaire-Dethiou M-C; Ceuterick C; Van Gerwen V; Cuesta A; Pedrola L; Palau F; Gabreëls-Festen A A W M; Verellen C; Tan E; Demirci M; Van Broeckhoven C; De Jonghe P; Topaloglu H; Timmerman V
Mutations in GDAP1: autosomal recessive CMT with demyelination and axonopathy.
Neurology 2002;59(12):1865-72.
2002: Kumar-Singh Samir; Julliams Ann; Nuydens Rony; Ceuterick Chantal; Labeur Christine; Serneels Sally; Vennekens Krist'l; Van Osta Peter; Geerts Hugo; De Strooper Bart; Van Broeckhoven Christine
In vitro studies of Flemish, Dutch, and wild-type beta-amyloid provide evidence for two-staged neurotoxicity.
Neurobiology of disease 2002;11(2):330-40.
2002: Ekici Arif B; Oezbey Sevinc; Fuchs Christina; Nelis Eva; Van Broeckhoven Christine; Schachner Melitta; Rautenstrauss Bernd
Tracing myelin protein zero (P0) in vivo by construction of P0-GFP fusion proteins.
BMC cell biology 2002;3():29.
2002: Nelis Eva; Erdem Sevim; Tan Ersin; Löfgren Ann; Ceuterick Chantal; De Jonghe Peter; Van Broeckhoven Christine; Timmerman Vincent; Topaloglu Haluk
A novel homozygous missense mutation in the myotubularin-related protein 2 gene associated with recessive Charcot-Marie-Tooth disease with irregularly folded myelin sheaths.
Neuromuscular disorders : NMD 2002;12(9):869-73.
2002: Ponsaerts Peter; Van den Bosch Glenn; Cools Nathalie; Van Driessche Ann; Nijs Griet; Lenjou Marc; Lardon Filip; Van Broeckhoven Christine; Van Bockstaele Dirk R; Berneman Zwi N; Van Tendeloo Viggo F I
Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(4):1669-75.
2002: Kumar-Singh Samir; Cras Patrick; Wang Rong; Kros John M; van Swieten Johan; Lübke Ursula; Ceuterick Chantal; Serneels Sally; Vennekens Krist'l; Timmermans Jean-Pierre; Van Marck Eric; Martin Jean-Jacques; van Duijn Cornelia M; Van Broeckhoven Christine
Dense-core senile plaques in the Flemish variant of Alzheimer's disease are vasocentric.
The American journal of pathology 2002;161(2):507-20.
2002: Roks G; Cruts M; Houwing-Duistermaat J J; Dermaut B; Serneels S; Havekes L M; Hofman A; Breteler M M B; Van Broeckhoven C; van Duijn C M
Effect of the APOE-491A/T promoter polymorphism on apolipoprotein E levels and risk of Alzheimer disease: The Rotterdam Study.
American journal of medical genetics 2002;114(5):570-3.
2002: Ponsaerts P; Van Tendeloo V F I; Cools N; Van Driessche A; Lardon F; Nijs G; Lenjou M; Mertens G; Van Broeckhoven C; Van Bockstaele D R; Berneman Z N
mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(7):1324-30.
2002: Irobi Joy; Nelis Eva; Verhoeven Kristien; De Vriendt Els; Dierick Ines; De Jonghe Peter; Van Broeckhoven Christine; Timmerman Vincent
Mutation analysis of 12 candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3.
Journal of the peripheral nervous system : JPNS 2002;7(2):87-95.
2002: Rosso S M; Roks G; Cruts M; van Broeckhoven C; Heutink P; van Duijn C M; van Swieten J C
Apolipoprotein E4 in the temporal variant of frontotemporal dementia.
Journal of neurology, neurosurgery, and psychiatry 2002;72(6):820.
2002: Dermaut Bart; Theuns Jessie; Sleegers Kristel; Hasegawa Hiroshi; Van den Broeck Marleen; Vennekens Krist'l; Corsmit Ellen; St George-Hyslop Peter; Cruts Marc; van Duijn Cornelia M; Van Broeckhoven Christine
The gene encoding nicastrin, a major gamma-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample.
American journal of human genetics 2002;70(6):1568-74.
2002: Del-Favero Jurgen; Gestel Sofie Van; Børglum Anders D; Muir Walter; Ewald Henrik; Mors Ole; Ivezic Sladana; Oruc Lilijana; Adolfsson Rolf; Blackwood Douglas; Kruse Torben; Mendlewicz Julien; Schalling Martin; Van Broeckhoven Christine
European combined analysis of the CTG18.1 and the ERDA1 CAG/CTG repeats in bipolar disorder.
European journal of human genetics : EJHG 2002;10(4):276-80.
2002: Van Goethem Gert; Martin Jean-Jacques; Van Broeckhoven Christine
Progressive external ophthalmoplegia and multiple mitochondrial DNA deletions.
Acta neurologica Belgica 2002;102(1):39-42.
2002: Visser Pieter Jelle; Verhey Frans R J; Scheltens Philip; Cruts Marc; Ponds Rudolf W H M; Van Broeckhoven Christine L; Jolles Jellemer
Diagnostic accuracy of the Preclinical AD Scale (PAS) in cognitively mildly impaired subjects.
Journal of neurology 2002;249(3):312-9.
2002: Villafuerte Sandra M; Del-Favero Jurgen; Adolfsson Rolf; Souery Daniel; Massat Isabelle; Mendlewicz Julien; Van Broeckhoven Christine; Claes Stephan
Gene-based SNP genetic association study of the corticotropin-releasing hormone receptor-2 (CRHR2) in major depression.
American journal of medical genetics 2002;114(2):222-6.
2002: Massat Isabelle; Souery Daniel; Del-Favero Jurgen; Van Gestel Sofie; Serretti Alessandro; Macciardi Fabio; Smeraldi Enrico; Kaneva Radka; Adolfsson Rolf; Nylander Peter O; Blackwood Douglas; Muir Walter; Papadimitriou George N; Dikeos Dimitris; Oruc Lilijana; Segman Ronnen H; Ivezic Sladjana; Aschauer Harold; Ackenheil Manfred; Fuchshuber S; Dam Henrik; Jakovljevic Miro; Peltonen Leena; Hilger Christiane; Hentges François; Staner Luc; Milanova Vihra; Jazin Elena; Lerer Bernard; Van Broeckhoven Christine; Mendlewicz Julien
Positive association of dopamine D2 receptor polymorphism with bipolar affective disorder in a European Multicenter Association Study of affective disorders.
American journal of medical genetics 2002;114(2):177-85.
2002: Rademakers R; Cruts M; Dermaut B; Sleegers K; Rosso S M; Van den Broeck M; Backhovens H; van Swieten J; van Duijn C M; Van Broeckhoven C
Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval.
Molecular psychiatry 2002;7(10):1064-74.
2002: Van Gestel S; Forsgren T; Claes S; Del-Favero J; Van Duijn C M; Sluijs S; Nilsson L-G; Adolfsson R; Van Broeckhoven C
Epistatic effect of genes from the dopamine and serotonin systems on the temperament traits of novelty seeking and harm avoidance.
Molecular psychiatry 2002;7(5):448-50.
2002: Massat I; Souery D; Del-Favero J; Oruc L; Noethen M M; Blackwood D; Thomson M; Muir W; Papadimitriou G N; Dikeos D G; Kaneva R; Serretti A; Lilli R; Smeraldi E; Jakovljevic M; Folnegovic V; Rietschel M; Milanova V; Valente F; Van Broeckhoven C; Mendlewicz J
Excess of allele1 for alpha3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association study.
Molecular psychiatry 2002;7(2):201-7.
2001: Dermaut B; Kumar-Singh S; De Jonghe C; Cruts M; Löfgren A; Lübke U; Cras P; Dom R; De Deyn P P; Martin J J; Van Broeckhoven C
Cerebral amyloid angiopathy is a pathogenic lesion in Alzheimer's disease due to a novel presenilin 1 mutation.
Brain : a journal of neurology 2001;124(Pt 12):2383-92.
2001: Irobi J; Nelis E; Meuleman J; Venken K; De Jonghe P; Van Broeckhoven C; Timmerman V
Exclusion of 5 functional candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3.
Annals of human genetics 2001;65(Pt 6):517-29.
2001: Dermaut B; Roks G; Theuns J; Rademakers R; Houwing-Duistermaat J J; Serneels S; Hofman A; Breteler M M; Cruts M; Van Broeckhoven C; van Duijn C M
Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's disease.
Journal of neurology 2001;248(11):935-9.
2001: Matilla A; Gorbea C; Einum D D; Townsend J; Michalik A; van Broeckhoven C; Jensen C C; Murphy K J; Ptácek L J; Fu Y H
Association of ataxin-7 with the proteasome subunit S4 of the 19S regulatory complex.
Human molecular genetics 2001;10(24):2821-31.
2001: Cataldo A; Rebeck G W; Ghetri B; Hulette C; Lippa C; Van Broeckhoven C; van Duijn C; Cras P; Bogdanovic N; Bird T; Peterhoff C; Nixon R
Endocytic disturbances distinguish among subtypes of Alzheimer's disease and related disorders.
Annals of neurology 2001;50(5):661-5.
2001: Cruts M; Dermaut B; Rademakers R; Roks G; Van den Broeck M; Munteanu G; van Duijn C M; Van Broeckhoven C
Amyloid beta secretase gene (BACE) is neither mutated in nor associated with early-onset Alzheimer's disease.
Neuroscience letters 2001;313(1-2):105-7.
2001: Van Everbroeck B; Croes E A; Pals P; Dermaut B; Jansen G; van Duijn C M; Cruts M; Van Broeckhoven C; Martin J J; Cras P
Influence of the prion protein and the apolipoprotein E genotype on the Creutzfeldt-Jakob Disease phenotype.
Neuroscience letters 2001;313(1-2):69-72.
2001: Goossens D; Del-Favero J; Van Broeckhoven C
Trinucleotide repeat expansions: do they contribute to bipolar disorder?
Brain research bulletin 2001;56(3-4):243-57.
2001: Kuhlenbäumer G; Meuleman J; De Jonghe P; Falck B; Young P; Hünermund G; Van Broeckhoven C; Timmerman V; Stögbauer F
Hereditary Neuralgic Amyotrophy (HNA) is genetically heterogeneous.
Journal of neurology 2001;248(10):861-5.
2001: Fujigasaki H; Martin J J; De Deyn P P; Camuzat A; Deffond D; Stevanin G; Dermaut B; Van Broeckhoven C; Dürr A; Brice A
CAG repeat expansion in the TATA box-binding protein gene causes autosomal dominant cerebellar ataxia.
Brain : a journal of neurology 2001;124(Pt 10):1939-47.
2001: Arango D; Cruts M; Torres O; Backhovens H; Serrano M L; Villareal E; Montañes P; Matallana D; Cano C; Van Broeckhoven C; Jacquier M
Systematic genetic study of Alzheimer disease in Latin America: mutation frequencies of the amyloid beta precursor protein and presenilin genes in Colombia.
American journal of medical genetics 2001;103(2):138-43.
2001: Massat I; Souery D; Del-Favero J; Oruc L; Jakovljevic M; Folnegovic V; Adolfsson R; Kaneva R; Papadimitriou G; Dikeos D; Jazin E; Milanova V; Van Broeckhoven C; Mendlewicz J
Lack of association between GABRA3 and unipolar affective disorder: a multicentre study.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2001;4(3):273-8.
2001: Slooter A J; Cruts M; Van Broeckhoven C; Hofman A; van Duijin C M
Apolipoprotein E and longevity: the Rotterdam Study.
Journal of the American Geriatrics Society 2001;49(9):1258-9.
2001: Slooter A J; Bots M L; Havekes L M; del Sol A I; Cruts M; Grobbee D E; Hofman A; Van Broeckhoven C; Witteman J C; van Duijn C M
Apolipoprotein E and carotid artery atherosclerosis: the Rotterdam study.
Stroke; a journal of cerebral circulation 2001;32(9):1947-52.
2001: Lerer B; Macciardi F; Segman R H; Adolfsson R; Blackwood D; Blairy S; Del Favero J; Dikeos D G; Kaneva R; Lilli R; Massat I; Milanova V; Muir W; Noethen M; Oruc L; Petrova T; Papadimitriou G N; Rietschel M; Serretti A; Souery D; Van Gestel S; Van Broeckhoven C; Mendlewicz J
Variability of 5-HT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorder.
Molecular psychiatry 2001;6(5):579-85.
2001: Ismailov S M; Fedotov V P; Dadali E L; Polyakov A V; Van Broeckhoven C; Ivanov V I; De Jonghe P; Timmerman V; Evgrafov O V
A new locus for autosomal dominant Charcot-Marie-Tooth disease type 2 (CMT2F) maps to chromosome 7q11-q21.
European journal of human genetics : EJHG 2001;9(8):646-50.
2001: Michalik A; Kazantsev A; Van Broeckhoven C
Method to introduce stable, expanded, polyglutamine-encoding CAG/CAA trinucleotide repeats into CAG repeat-containing genes.
BioTechniques 2001;31(2):250-2, 254.
2001: De Jonghe C; Esselens C; Kumar-Singh S; Craessaerts K; Serneels S; Checler F; Annaert W; Van Broeckhoven C; De Strooper B
Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.
Human molecular genetics 2001;10(16):1665-71.
2001: Meuleman J; Timmerman V; Van Broeckhoven C; De Jonghe P
Hereditary neuralgic amyotrophy.
Neurogenetics 2001;3(3):115-8.
2001: Roks G; Cruts M; Slooter A J; Dermaut B; Hofman A; Van Broeckhoven C; Van Duijn C M
The cystatin C polymorphism is not associated with early onset Alzheimer's disease.
Neurology 2001;57(2):366-7.
2001: Van Goethem G; Dermaut B; Löfgren A; Martin J J; Van Broeckhoven C
Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions.
Nature genetics 2001;28(3):211-2.
2001: Van Tendeloo V F; Ponsaerts P; Lardon F; Nijs G; Lenjou M; Van Broeckhoven C; Van Bockstaele D R; Berneman Z N
Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells.
Blood 2001;98(1):49-56.
2001: Theuns J; Feuk L; Dermaut B; Del-Favero J; Roks G; Van den Bossche D; Corsmit E; Van den Broeck M; van Duijn C M; Cruts M; Brookes A J; Van Broeckhoven C
The TNFRSF6 gene is not implicated in familial early-onset Alzheimer's disease.
Human genetics 2001;108(6):552-3.
2001: Claes L; Del-Favero J; Ceulemans B; Lagae L; Van Broeckhoven C; De Jonghe P
De novo mutations in the sodium-channel gene SCN1A cause severe myoclonic epilepsy of infancy.
American journal of human genetics 2001;68(6):1327-32.
2001: Meuleman J; Kuhlenbäumer G; Audenaert D; Hünermund G; Hor H; Young P; Stögbauer F; Ringelstein E B; Van Broeckhoven C; De Jonghe P; Timmerman V
Mutation analysis of 4 candidate genes for hereditary neuralgic amyotrophy (HNA).
Human genetics 2001;108(5):390-3.
2001: Meuleman J; Pou-Serradell A; Löfgren A; Ceuterick C; Martin J J; Timmerman V; Van Broeckhoven C; De Jonghe P
A novel 3'-splice site mutation in peripheral myelin protein 22 causing hereditary neuropathy with liability to pressure palsies.
Neuromuscular disorders : NMD 2001;11(4):400-3.
2001: Van Tendeloo V F; Van Broeckhoven C; Berneman Z N
Gene-based cancer vaccines: an ex vivo approach.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(4):545-58.
2001: Van Tendeloo V F; Van Broeckhoven C; Berneman Z N
Gene therapy: principles and applications to hematopoietic cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(4):523-44.
2001: Jacquier M; Arango D; Villareal E; Torres O; Serrano M L; Cruts M; Montañes P; Cano C; Rodriguez M N; Serneels S; Van Broeckhoven C
APOE epsilon4 and Alzheimer's disease: positive association in a Colombian clinical series and review of the Latin-American studies.
Arquivos de neuro-psiquiatria 2001;59(1):11-7.
2001: Souery D; Van Gestel S; Massat I; Blairy S; Adolfsson R; Blackwood D; Del-Favero J; Dikeos D; Jakovljevic M; Kaneva R; Lattuada E; Lerer B; Lilli R; Milanova V; Muir W; Nöthen M; Oruc L; Papadimitriou G; Propping P; Schulze T; Serretti A; Shapira B; Smeraldi E; Stefanis C; Thomson M; Van Broeckhoven C; Mendlewicz J
Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association study.
Biological psychiatry 2001;49(5):405-9.
2001: De Jonghe P; Mersivanova I; Nelis E; Del Favero J; Martin J J; Van Broeckhoven C; Evgrafov O; Timmerman V
Further evidence that neurofilament light chain gene mutations can cause Charcot-Marie-Tooth disease type 2E.
Annals of neurology 2001;49(2):245-9.
2001: Roymans D; Vissenberg K; De Jonghe C; Grobben B; Claes P; Verbelen J P; Van Broeckhoven C; Slegers H
Phosphatidylinositol 3-kinase activity is required for the expression of glial fibrillary acidic protein upon cAMP-dependent induction of differentiation in rat C6 glioma.
Journal of neurochemistry 2001;76(2):610-8.
2001: Roymans D; Vissenberg K; De Jonghe C; Willems R; Engler G; Kimura N; Grobben B; Claes P; Verbelen J P; Van Broeckhoven C; Slegers H
Identification of the tumor metastasis suppressor Nm23-H1/Nm23-R1 as a constituent of the centrosome.
Experimental cell research 2001;262(2):145-53.
2001: Ceuterick-de Groote C; De Jonghe P; Timmerman V; Van Goethem G; Löfgren A; Ceulemans B; Van Broeckhoven C; Martin J J
Infantile demyelinating neuropathy associated with a de novo point mutation on Ser72 in PMP22 and basal lamina onion bulbs in skin biopsy.
Pathology, research and practice 2001;197(3):193-8.
2000: Singleton A B; Hall R; Ballard C G; Perry R H; Xuereb J H; Rubinsztein D C; Tysoe C; Matthews P; Cordell B; Kumar-Singh S; De Jonghe C; Cruts M; van Broeckhoven C; Morris C M
Pathology of early-onset Alzheimer's disease cases bearing the Thr113-114ins presenilin-1 mutation.
Brain : a journal of neurology 2000;123 Pt 12():2467-74.
2000: Roymans D; Willems R; Vissenberg K; De Jonghe C; Grobben B; Claes P; Lascu I; Van Bockstaele D; Verbelen J P; Van Broeckhoven C; Slegers H
Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma.
Experimental cell research 2000;261(1):127-38.
2000: Houlden H; Baker M; McGowan E; Lewis P; Hutton M; Crook R; Wood N W; Kumar-Singh S; Geddes J; Swash M; Scaravilli F; Holton J L; Lashley T; Tomita T; Hashimoto T; Verkkoniemi A; Kalimo H; Somer M; Paetau A; Martin J J; Van Broeckhoven C; Golde T; Hardy J; Haltia M; Revesz T
Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations.
Annals of neurology 2000;48(5):806-8.
2000: Kumar-Singh S; De Jonghe C; Cruts M; Kleinert R; Wang R; Mercken M; De Strooper B; Vanderstichele H; Löfgren A; Vanderhoeven I; Backhovens H; Vanmechelen E; Kroisel P M; Van Broeckhoven C
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.
Human molecular genetics 2000;9(18):2589-98.
2000: Timmerman V; De Jonghe P; Van Broeckhoven C
Of giant axons and curly hair.
Nature genetics 2000;26(3):254-5.
2000: Theuns J; Van Broeckhoven C
Transcriptional regulation of Alzheimer's disease genes: implications for susceptibility.
Human molecular genetics 2000;9(16):2383-94.
2000: Roks G; Van Harskamp F; De Koning I; Cruts M; De Jonghe C; Kumar-Singh S; Tibben A; Tanghe H; Niermeijer M F; Hofman A; Van Swieten J C; Van Broeckhoven C; Van Duijn C M
Presentation of amyloidosis in carriers of the codon 692 mutation in the amyloid precursor protein gene (APP692).
Brain : a journal of neurology 2000;123 ( Pt 10)():2130-40.
2000: Stögbauer F; Timmerman V; Van Broeckhoven C
71st ENMC International Workshop, 6th workshop of the European Charcot-Marie-Tooth disease consortium: hereditary recurrent focal neuropathies, 24-25 September 1999, Soestduinen, the Netherlands.
Neuromuscular disorders : NMD 2000;10(7):518-24.
2000: Croes E A; Dermaut B; van Der Cammen T J; van Broeckhoven C; van Duijn C M
Genetic testing should not be advocated as a diagnostic tool in familial forms of dementia.
American journal of human genetics 2000;67(4):1033-5.
2000: Young P; Stögbauer F; Eller B; de Jonghe P; Löfgren A; Timmerman V; Rautenstrauss B; Oexle K; Grehl H; Kuhlenbäumer G; Van Broeckhoven C; Ringelstein E B; Funke H
PMP22 Thr118Met is not a clinically relevant CMT1 marker.
Journal of neurology 2000;247(9):696-700.
2000: Koster M N; Dermaut B; Cruts M; Houwing-Duistermaat J J; Roks G; Tol J; Ott A; Hofman A; Munteanu G; Breteler M M; van Duijn C M; Van Broeckhoven C
The alpha2-macroglobulin gene in AD: a population-based study and meta-analysis.
Neurology 2000;55(5):678-84.
2000: Van Tendeloo V F; Ponsaerts P; Van Broeckhoven C; Berneman Z N; Van Bockstaele D R
Efficient generation of stably electrotransfected human hematopoietic cell lines without drug selection by consecutive FACsorting.
Cytometry 2000;41(1):31-5.
2000: Van Tendeloo V F; Willems R; Ponsaerts P; Lenjou M; Nijs G; Vanhove M; Muylaert P; Van Cauwelaert P; Van Broeckhoven C; Van Bockstaele D R; Berneman Z N
High-level transgene expression in primary human T lymphocytes and adult bone marrow CD34+ cells via electroporation-mediated gene delivery.
Gene therapy 2000;7(16):1431-7.
2000: Van Gassen G; De Jonghe C; Nishimura M; Yu G; Kuhn S; St George-Hyslop P; Van Broeckhoven C
Evidence that the beta-catenin nuclear translocation assay allows for measuring presenilin 1 dysfunction.
Molecular medicine (Cambridge, Mass.) 2000;6(7):570-80.
2000: van Goethem G; Löfgren A; Martin J J; van Broeckhoven C
Further evidence for genetic heterogeneity of autosomal dominant disorders with accumulation of multiple deletions of mitochondrial DNA.
Journal of medical genetics 2000;37(7):547-8.
2000: McInnis M G; Swift-Scanlanl T; Mahoney A T; Vincent J; Verheyen G; Lan T H; Oruc L; Riess O; Van Broeckhoven C; Chen H; Kennedy J L; MacKinnon D F; Margolis R L; Simpson S G; McMahon F J; Gershon E; Nurnberger J; Reich T; DePaulo J R; Ross C A
Allelic distribution of CTG18.1 in Caucasian populations: association studies in bipolar disorder, schizophrenia, and ataxia.
Molecular psychiatry 2000;5(4):439-42.
2000: Van Gassen G; Van Broeckhoven C
Molecular genetics of Alzheimer's disease: what have we learned?
Acta neurologica Belgica 2000;100(2):65-76.
2000: DeLisi L E; Craddock N J; Detera-Wadleigh S; Foroud T; Gejman P; Kennedy J L; Lendon C; Macciardi F; McKeon P; Mynett-Johnson L; Nurnberger J I; Paterson A; Schwab S; Van Broeckhoven C; Wildenauer D; Crow T J
Update on chromosomal locations for psychiatric disorders: report of the interim meeting of chromosome workshop chairpersons from the VIIth World Congress of Psychiatric Genetics, Monterey, California, October 14-18, 1999.
American journal of medical genetics 2000;96(3):434-49.
2000: Blairy S; Massat I; Staner L; Le Bon O; Van Gestel S; Van Broeckhoven C; Hilger C; Hentges F; Souery D; Mendlewicz J
5-HT2a receptor polymorphism gene in bipolar disorder and harm avoidance personality trait.
American journal of medical genetics 2000;96(3):360-4.
2000: Wauters M; Considine R; Löfgren A; Van Broeckhoven C; Van der Auwera J C; De Leeuw I; Van Gaal L
Associations of leptin with body fat distribution and metabolic parameters in non-insulin-dependent diabetic patients: no effect of apolipoprotein E polymorphism.
Metabolism: clinical and experimental 2000;49(6):724-30.
2000: Van Gassen G; Annaert W; Van Broeckhoven C
Binding partners of Alzheimer's disease proteins: are they physiologically relevant?
Neurobiology of disease 2000;7(3):135-51.
2000: Dermaut B; Cruts M; Backhovens H; Lübke U; Van Everbroeck B; Sciot R; Dom R; Martin J J; Van Broeckhoven C; Cras P
Familial Creutzfeldt-Jakob disease in a patient carrying both a presenilin 1 missense substitution and a prion protein gene insertion.
Journal of neurology 2000;247(5):364-8.
2000: Goossens D; Villafuerte S; Tissir F; Van Gestel S; Claes S; Souery D; Massat I; Van den Bossche D; Van Zand K; Mendlewicz J; Van Broeckhoven C; Del-Favero J
No evidence for the involvement of CAG/CTG repeats from within 18q21.33-q23 in bipolar disorder.
European journal of human genetics : EJHG 2000;8(5):385-8.
2000: Massat I; Souery D; Lipp O; Blairy S; Papadimitriou G; Dikeos D; Ackenheil M; Fuchshuber S; Hilger C; Kaneva R; Milanova V; Verheyen G; Raeymaekers P; Staner L; Oruc L; Jakovljevic M; Serretti A; Macciardi F; Van Broeckhoven C; Mendlewicz J
A European multicenter association study of HTR2A receptor polymorphism in bipolar affective disorder.
American journal of medical genetics 2000;96(2):136-40.
2000: Irobi J; Tissir F; De Jonghe P; De Vriendt E; Van Broeckhoven C; Timmerman V; Beuten J
A clone contig of 12q24.3 encompassing the distal hereditary motor neuropathy type II gene.
Genomics 2000;65(1):34-43.
2000: Visser P J; Verhey F R; Ponds R W; Cruts M; Van Broeckhoven C L; Jolles J
Course of objective memory impairment in non-demented subjects attending a memory clinic and predictors of outcome.
International journal of geriatric psychiatry 2000;15(4):363-72.
2000: Serretti A; Macciardi F; Cusin C; Lattuada E; Souery D; Lipp O; Mahieu B; Van Broeckhoven C; Blackwood D; Muir W; Aschauer H N; Heiden A M; Ackenheil M; Fuchshuber S; Raeymaekers P; Verheyen G; Kaneva R; Jablensky A; Papadimitriou G N; Dikeos D G; Stefanis C N; Smeraldi E; Mendlewicz J
Linkage of mood disorders with D2, D3 and TH genes: a multicenter study.
Journal of affective disorders 2000;58(1):51-61.
2000: Van Gestel S; Houwing-Duistermaat J J; Adolfsson R; van Duijn C M; Van Broeckhoven C
Power of selective genotyping in genetic association analyses of quantitative traits.
Behavior genetics 2000;30(2):141-6.
2000: Harhangi B S; de Rijk M C; van Duijn C M; Van Broeckhoven C; Hofman A; Breteler M M
APOE and the risk of PD with or without dementia in a population-based study.
Neurology 2000;54(6):1272-6.
2000: Kumar-Singh S; Dewachter I; Moechars D; Lübke U; De Jonghe C; Ceuterick C; Checler F; Naidu A; Cordell B; Cras P; Van Broeckhoven C; Van Leuven F
Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.
Neurobiology of disease 2000;7(1):9-22.
2000: Theuns J; Del-Favero J; Dermaut B; van Duijn C M; Backhovens H; Van den Broeck M V; Serneels S; Corsmit E; Van Broeckhoven C V; Cruts M
Genetic variability in the regulatory region of presenilin 1 associated with risk for Alzheimer's disease and variable expression.
Human molecular genetics 2000;9(3):325-31.
2000: Martini R; Berciano J; Van Broeckhoven C
5th Workshop of the European CMT Consortium, 69th ENMC International Workshop: therapeutic approaches in CMT neuropathies and related disorders 23-25 April 1999, Soestduinen, The Netherlands.
Neuromuscular disorders : NMD 2000;10(1):69-74.
2000: Mersiyanova I V; Ismailov S M; Polyakov A V; Dadali E L; Fedotov V P; Nelis E; Löfgren A; Timmerman V; van Broeckhoven C; Evgrafov O V
Screening for mutations in the peripheral myelin genes PMP22, MPZ and Cx32 (GJB1) in Russian Charcot-Marie-Tooth neuropathy patients.
Human mutation 2000;15(4):340-7.
2000: Leonardis L; Zidar J; Popovic M; Timmerman V; Löfgren A; Van Broeckhoven C; Butinar D
Hereditary motor and sensory neuropathy associated with auditory neuropathy in a Gypsy family.
Pflügers Archiv : European journal of physiology 2000;439(3 Suppl):R208-10.
1999: Mauger C; Del-Favero J; Ceuterick C; Lübke U; van Broeckhoven C; Martin J
Identification and localization of ataxin-7 in brain and retina of a patient with cerebellar ataxia type II using anti-peptide antibody.
Brain research. Molecular brain research 1999;74(1-2):35-43.
1999: Roks G; Dermaut B; Heutink P; Julliams A; Backhovens H; Van de Broeck M; Serneels S; Hofman A; Van Broeckhoven C; van Duijn C M; Cruts M
Mutation screening of the tau gene in patients with early-onset Alzheimer's disease.
Neuroscience letters 1999;277(2):137-9.
1999: Kuhlenbäumer G; Schirmacher A; Meuleman J; Tissir F; Del-Favero J; Stögbauer F; Young P; Ringelstein B; Van Broeckhoven C; Timmerman V
A sequence-ready BAC/PAC contig and partial transcript map of approximately 1.5 Mb in human chromosome 17q25 comprising multiple disease genes.
Genomics 1999;62(2):242-50.
1999: Meulemann J; Kuhlenbäumer G; Schirmacher A; Wehnert M; De Jonghe P; De Vriendt E; Young P; Airaksinen E; Pou-Serradell A; Prats J M; Ringelstein B; Stögbauer F; Van Broeckhoven C; Timmerman V
Genetic refinement of the hereditary neuralgic amyotrophy (HNA) locus at chromosome 17q25.
European journal of human genetics : EJHG 1999;7(8):920-7.
1999: Slooter A J; Bronzova J; Witteman J C; Van Broeckhoven C; Hofman A; van Duijn C M
Estrogen use and early onset Alzheimer's disease: a population-based study.
Journal of neurology, neurosurgery, and psychiatry 1999;67(6):779-81.
1999: Michalík A; Del-Favero J; Mauger C; Löfgren A; Van Broeckhoven C
Genomic organisation of the spinocerebellar ataxia type 7 (SCA7) gene responsible for autosomal dominant cerebellar ataxia with retinal degeneration.
Human genetics 1999;105(5):410-7.
1999: Wang S Y; Cruts M; Del-Favero J; Zhang Y; Tissir F; Potier M C; Patterson D; Nizetic D; Bosch A; Chen H; Bennett L; Estivill X; Kessling A; Antonarakis S E; van Broeckhoven C
A high-resolution physical map of human chromosome 21p using yeast artificial chromosomes.
Genome research 1999;9(11):1059-73.
1999: van Duijn C M; Cruts M; Theuns J; Van Gassen G; Backhovens H; van den Broeck M; Wehnert A; Serneels S; Hofman A; Van Broeckhoven C
Genetic association of the presenilin-1 regulatory region with early-onset Alzheimer's disease in a population-based sample.
European journal of human genetics : EJHG 1999;7(7):801-6.
1999: Vanderhoeven I; Cras P; Martin J J; Van Broeckhoven C; De Jonghe C
Proteolytic processing of presenilin-1 in human lymphoblasts is not affected by the presence of the I143T and G384A mutations.
Neuroscience letters 1999;274(3):183-6.
1999: Slooter A J; Cruts M; Ott A; Bots M L; Witteman J C; Hofman A; Van Broeckhoven C; Breteler M M; van Duijn C M
The effect of APOE on dementia is not through atherosclerosis: the Rotterdam Study.
Neurology 1999;53(7):1593-5.
1999: Verheyen G R; Del-Favero J; Mendlewicz J; Lindblad K; Van Zand K; Aalbregtse M; Schalling M; Souery D; Van Broeckhoven C
Molecular interpretation of expanded RED products in bipolar disorder by CAG/CTG repeats located at chromosomes 17q and 18q.
Neurobiology of disease 1999;6(5):424-32.
1999: Van Gassen G; De Jonghe C; Pype S; Van Criekinge W; Julliams A; Vanderhoeven I; Woodrow S; Beyaert R; Huylebroeck D; Van Broeckhoven C
Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome.
Neurobiology of disease 1999;6(5):376-91.
1999: De Jonghe P; Timmerman V; Nelis E; De Vriendt E; Löfgren A; Ceuterick C; Martin J J; Van Broeckhoven C
A novel type of hereditary motor and sensory neuropathy characterized by a mild phenotype.
Archives of neurology 1999;56(10):1283-8.
1999: Del-Favero J; Goossens D; De Jonghe P; Benson K; Michalik A; Van den Bossche D; Horwitz M; Van Broeckhoven C
Isolation of CAG/CTG repeats from within the chromosome 2p21-p24 locus for autosomal dominant spastic paraplegia (SPG4) by YAC fragmentation.
Human genetics 1999;105(3):217-25.
1999: Kochanski A; Timmerman V; Jedrzejowska H; Ryniewicz B; Löfgren A; De Vriendt E; Van Broeckhoven C; Latos-Bielenska A; Hausmanowa-Petrusewicz I
Mutation screening of Charcot-Marie-Tooth patients in Poland.
Annals of the New York Academy of Sciences 1999;883():493-6.
1999: Irobi J; Timmerman V; De Jonghe P; De Vriendt E; Van Broeckhoven C; Beuten J
Construction of a PAC contig within the distal hereditary motor neuropathy type II candidate region at 12q24.
Annals of the New York Academy of Sciences 1999;883():463-5.
1999: Löfgren A; De Vos A; Sermon K; Liebaers I; Van Steirteghem A; Van Broeckhoven C
Preimplantation diagnosis for Charcot-Marie-Tooth type 1A.
Annals of the New York Academy of Sciences 1999;883():460-2.
1999: Kuhlenbäumer G; Young P; Kiefer R; Timmerman V; Wang J F; Schroeder J M; Weis J; Ringelstein E B; Van Broeckhoven C; Stoegbauer F
A second family with autosomal dominant burning feet syndrome.
Annals of the New York Academy of Sciences 1999;883():445-8.
1999: Meuleman J; Kuhlenbäumer G; Schirmacher A; Wehnert M; Young P; Stögbauer F; Ringelstein E B; Van Broeckhoven C; Timmerman V
Hereditary neuralgic amyotrophy: mutation analysis of candidate genes.
Annals of the New York Academy of Sciences 1999;883():443-4.
1999: De Jonghe P; Nelis E; Timmerman V; Löfgren A; Martin J J; Van Broeckhoven C
Molecular diagnostic testing in Charcot-Marie-Tooth disease and related disorders. Approaches and results.
Annals of the New York Academy of Sciences 1999;883():389-96.
1999: Timmerman V; Beuten J; Irobi J; De Jonghe P; Martin J J; Van Broeckhoven C
Distal hereditary motor neuropathy type II (distal HMN type II): phenotype and molecular genetics.
Annals of the New York Academy of Sciences 1999;883():60-4.
1999: Nelis E; Timmerman V; De Jonghe P; Van Broeckhoven C; Rautenstrauss B
Molecular genetics and biology of inherited peripheral neuropathies: a fast-moving field.
Neurogenetics 1999;2(3):137-48.
1999: Martin J; Van Regemorter N; Del-Favero J; Löfgren A; Van Broeckhoven C
Spinocerebellar ataxia type 7 (SCA7) - correlations between phenotype and genotype in one large Belgian family.
Journal of the neurological sciences 1999;168(1):37-46.
1999: De Jonghe C; Cras P; Vanderstichele H; Cruts M; Vanderhoeven I; Smouts I; Vanmechelen E; Martin J J; Hendriks L; Van Broeckhoven C
Evidence that Abeta42 plasma levels in presenilin-1 mutation carriers do not allow for prediction of their clinical phenotype.
Neurobiology of disease 1999;6(4):280-7.
1999: De Jonghe C; Cruts M; Rogaeva E A; Tysoe C; Singleton A; Vanderstichele H; Meschino W; Dermaut B; Vanderhoeven I; Backhovens H; Vanmechelen E; Morris C M; Hardy J; Rubinsztein D C; St George-Hyslop P H; Van Broeckhoven C
Aberrant splicing in the presenilin-1 intron 4 mutation causes presenile Alzheimer's disease by increased Abeta42 secretion.
Human molecular genetics 1999;8(8):1529-40.
1999: Julliams A; Vanderhoeven I; Kuhn S; Van Broeckhoven C; De Jonghe C
No influence of presenilin1 I143T and G384A mutations on endogenous tau phosphorylation in human and mouse neuroblastoma cells.
Neuroscience letters 1999;269(2):83-6.
1999: Stögbauer F; Young P; Kuhlenbäumer G; Kiefer R; Timmerman V; Ringelstein E B; Wang J F; Schröder J M; Van Broeckhoven C; Weis J
Autosomal dominant burning feet syndrome.
Journal of neurology, neurosurgery, and psychiatry 1999;67(1):78-81.
1999: Van Broeckhoven C; Verheyen G
Report of the chromosome 18 workshop.
American journal of medical genetics 1999;88(3):263-70.
1999: Timmerman V; De Jonghe P; Ceuterick C; De Vriendt E; Löfgren A; Nelis E; Warner L E; Lupski J R; Martin J J; Van Broeckhoven C
Novel missense mutation in the early growth response 2 gene associated with Dejerine-Sottas syndrome phenotype.
Neurology 1999;52(9):1827-32.
1999: Verheyen G R; Villafuerte S M; Del-Favero J; Souery D; Mendlewicz J; Van Broeckhoven C; Raeymaekers P
Genetic refinement and physical mapping of a chromosome 18q candidate region for bipolar disorder.
European journal of human genetics : EJHG 1999;7(4):427-34.
1999: Liehr T; Kuhlenbäumer G; Wulf P; Taylor V; Suter U; Van Broeckhoven C; Lupski J R; Claussen U; Rautenstrauss B
Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3.
Genomics 1999;58(1):106-8.
1999: Slooter A J; Houwing-Duistermaat J J; van Harskamp F; Cruts M; Van Broeckhoven C; Breteler M M; Hofman A; Stijnen T; van Duijn C M
Apolipoprotein E genotype and progression of Alzheimer's disease: the Rotterdam Study.
Journal of neurology 1999;246(4):304-8.
1999: Theuns J; Cruts M; Del-Favero J; Goossens D; Dauwerse H; Wehnert A; den Dunnen J T; Van Broeckhoven C
Determination of the genomic organization of human presenilin 1 by fiber-FISH analysis and restriction mapping of cloned DNA.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(4):410-4.
1999: Del-Favero J; Goossens D; Van den Bossche D; Van Broeckhoven C
YAC fragmentation with repetitive and single-copy sequences: detailed physical mapping of the presenilin 1 gene on chromosome 14.
Gene 1999;229(1-2):193-201.
1999: Bähr M; Andres F; Timmerman V; Nelis M E; Van Broeckhoven C; Dichgans J
Central visual, acoustic, and motor pathway involvement in a Charcot-Marie-Tooth family with an Asn205Ser mutation in the connexin 32 gene.
Journal of neurology, neurosurgery, and psychiatry 1999;66(2):202-6.
1999: De Jonghe P; Timmerman V; Ceuterick C; Nelis E; De Vriendt E; Löfgren A; Vercruyssen A; Verellen C; Van Maldergem L; Martin J J; Van Broeckhoven C
The Thr124Met mutation in the peripheral myelin protein zero (MPZ) gene is associated with a clinically distinct Charcot-Marie-Tooth phenotype.
Brain : a journal of neurology 1999;122 ( Pt 2)():281-90.
1999: van de Craen M; de Jonghe C; van den Brande I; Declercq W; van Gassen G; van Criekinge W; Vanderhoeven I; Fiers W; van Broeckhoven C; Hendriks L; Vandenabeele P
Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases.
FEBS letters 1999;445(1):149-54.
1999: Dermaut B; Cruts M; Slooter A J; Van Gestel S; De Jonghe C; Vanderstichele H; Vanmechelen E; Breteler M M; Hofman A; van Duijn C M; Van Broeckhoven C
The Glu318Gly substitution in presenilin 1 is not causally related to Alzheimer disease.
American journal of human genetics 1999;64(1):290-2.
1999: Timmerman V; De Jonghe P; Van Broeckhoven C
Report of the 8th annual symposium of the European Charcot-Marie-Tooth Consortium, Antwerpen, Belgium, July 2-4, 1999.
Journal of the peripheral nervous system : JPNS 1999;4(3-4):279-304.
1999: Martin J; Martin L; Löfgren A; D'Hooghe M; Storm K; Balemans W; Palau F; Van Broeckhoven C
Classical Friedreich's ataxia and its genotype.
European neurology 1999;42(2):109-15.
1999: Stronach E A; Clark C; Bell C; Löfgren A; McKay N G; Timmerman V; Van Broeckhoven C; Haites N E
Novel PCR-based diagnostic tools for Charcot-Marie-Tooth type 1A and hereditary neuropathy with liability to pressure palsies.
Journal of the peripheral nervous system : JPNS 1999;4(2):117-22.
1999: Nelis E; Haites N; Van Broeckhoven C
Mutations in the peripheral myelin genes and associated genes in inherited peripheral neuropathies.
Human mutation 1999;13(1):11-28.
1998: Cruts M; Van Broeckhoven C
Molecular genetics of Alzheimer's disease.
Annals of medicine 1998;30(6):560-5.
1998: Roks G; Cruts M; Bullido M J; Backhovens H; Artiga M J; Hofman A; Valdivieso F; Van Broeckhoven C; Van Duijn C M
The -491 A/T polymorphism in the regulatory region of the apolipoprotein E gene and early-onset Alzheimer's disease.
Neuroscience letters 1998;258(2):65-8.
1998: De Jonghe C; Zehr C; Yager D; Prada C M; Younkin S; Hendriks L; Van Broeckhoven C; Eckman C B
Flemish and Dutch mutations in amyloid beta precursor protein have different effects on amyloid beta secretion.
Neurobiology of disease 1998;5(4):281-6.
1998: Ekici A B; Fuchs C; Nelis E; Hillenbrand R; Schachner M; Van Broeckhoven C; Rautenstrauss B
An adhesion test system based on Schneider cells to determine genotype-phenotype correlations for mutated P0 proteins.
Genetic analysis : biomolecular engineering 1998;14(4):117-9.
1998: De Vos A; Sermon K; Van de Velde H; Joris H; Vandervorst M; Lissens W; Mortier G; De Sutter P; Löfgren A; Van Broeckhoven C; Liebaers I; Van Steirteghem A
Pregnancy after preimplantation genetic diagnosis for Charcot-Marie-Tooth disease type 1A.
Molecular human reproduction 1998;4(10):978-84.
1998: Kuhlenbaeumer G; Meuleman J; Schirmacher A; Stoegbauer F; Ringelstein E B; Wehnert M; Hoeltzenbein M; Broeckhoven C V; Timmerman V
Mutation analysis of a putative sialyltransferase gene, the SFRS2 splicing factor gene and the c-myb ET-locus in two families with hereditary neuralgic amyotrophy (HNA).
Annals of human genetics 1998;62(Pt 5):397-400.
1998: Cras P; van Harskamp F; Hendriks L; Ceuterick C; van Duijn C M; Stefanko S Z; Hofman A; Kros J M; Van Broeckhoven C; Martin J J
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.
Acta neuropathologica 1998;96(3):253-60.
1998: Potier M; Dutriaux A; Orti R; Groet J; Gibelin N; Karadima G; Lutfalla G; Lynn A; Van Broeckhoven C; Chakravarti A; Petersen M; Nizetic D; Delabar J; Rossier J
Two sequence-ready contigs spanning the two copies of a 200-kb duplication on human 21q: partial sequence and polymorphisms.
Genomics 1998;51(3):417-26.
1998: Villanova M; Timmerman V; De Jonghe P; Malandrini A; Rizzuto N; Van Broeckhoven C; Guazzi G; Rossi A
Charcot-Marie-Tooth disease: an intermediate form.
Neuromuscular disorders : NMD 1998;8(6):392-3.
1998: van der Cammen T J; Verschoor C J; van Loon C P; van Harskamp F; de Koning I; Schudel W J; Slooter A J; Van Broeckhoven C; van Duijn C M
Risk of left ventricular dysfunction in patients with probable Alzheimer's disease with APOE*4 allele.
Journal of the American Geriatrics Society 1998;46(8):962-7.
1998: Nelis E; De Jonghe P; De Vriendt E; Patel P I; Martin J J; Van Broeckhoven C
Mutation analysis of the nerve specific promoter of the peripheral myelin protein 22 gene in CMT1 disease and HNPP.
Journal of medical genetics 1998;35(7):590-3.
1998: Slooter A J; Cruts M; Kalmijn S; Hofman A; Breteler M M; Van Broeckhoven C; van Duijn C M
Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: the Rotterdam Study.
Archives of neurology 1998;55(7):964-8.
1998: Klaver C C; Kliffen M; van Duijn C M; Hofman A; Cruts M; Grobbee D E; van Broeckhoven C; de Jong P T
Genetic association of apolipoprotein E with age-related macular degeneration.
American journal of human genetics 1998;63(1):200-6.
1998: Ott A; Slooter A J; Hofman A; van Harskamp F; Witteman J C; Van Broeckhoven C; van Duijn C M; Breteler M M
Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study.
Lancet 1998;351(9119):1840-3.
1998: Van Tendeloo V F; Snoeck H W; Lardon F; Vanham G L; Nijs G; Lenjou M; Hendriks L; Van Broeckhoven C; Moulijn A; Rodrigus I; Verdonk P; Van Bockstaele D R; Berneman Z N
Nonviral transfection of distinct types of human dendritic cells: high-efficiency gene transfer by electroporation into hematopoietic progenitor- but not monocyte-derived dendritic cells.
Gene therapy 1998;5(5):700-7.
1998: Slooter A J; de Knijff P; Hofman A; Cruts M; Breteler M M; Van Broeckhoven C; Havekes L M; van Duijn C M
Serum apolipoprotein E level is not increased in Alzheimer's disease: the Rotterdam study.
Neuroscience letters 1998;248(1):21-4.
1998: Tamaoka A; Fraser P E; Ishii K; Sahara N; Ozawa K; Ikeda M; Saunders A M; Komatsuzaki Y; Sherrington R; Levesque G; Yu G; Rogaeva E; Shoji S; Nee L E; Pollen D A; Hendriks L; Martin J J; Van Broeckhoven C; Roses A D; Farrer L A; St George-Hyslop P H; Mori H
Amyloid-beta-protein isoforms in brain of subjects with PS1-linked, beta APP-linked and sporadic Alzheimer disease.
Brain research. Molecular brain research 1998;56(1-2):178-85.
1998: Reiter L T; Hastings P J; Nelis E; De Jonghe P; Van Broeckhoven C; Lupski J R
Human meiotic recombination products revealed by sequencing a hotspot for homologous strand exchange in multiple HNPP deletion patients.
American journal of human genetics 1998;62(5):1023-33.
1998: Groet J; Ives J H; South A P; Baptista P R; Jones T A; Yaspo M L; Lehrach H; Potier M C; Van Broeckhoven C; Nizetic D
Bacterial contig map of the 21q11 region associated with Alzheimer's disease and abnormal myelopoiesis in Down syndrome.
Genome research 1998;8(4):385-98.
1998: Gambardella A; Bolino A; Muglia M; Valentino P; Bono F; Oliveri R L; Sabatelli M; Brancolini V; Van Broeckhoven C; Romeo G; Devoto M; Quattrone A
Genetic heterogeneity in autosomal recessive hereditary motor and sensory neuropathy with focally folded myelin sheaths (CMT4B).
Neurology 1998;50(3):799-801.
1998: Young P; Stögbauer F; Wiebusch H; Löfgren A; Timmerman V; Van Broeckhoven C; Ringelstein E B; Assmann G; Funke H
PCR-based strategy for the diagnosis of hereditary neuropathy with liability to pressure palsies and Charcot-Marie-Tooth disease type 1A.
Neurology 1998;50(3):760-3.
1998: Houlden H; Crook R; Backhovens H; Prihar G; Baker M; Hutton M; Rossor M; Martin J J; Van Broeckhoven C; Hardy J
ApoE genotype is a risk factor in nonpresenilin early-onset Alzheimer's disease families.
American journal of medical genetics 1998;81(1):117-21.
1998: Hendriks L; De Jonghe C; Lübke U; Woodrow S; Vanderhoeven I; Boons J; Cras P; Martin J J; Van Broeckhoven C
Immunoreactivity of presenilin-1 and tau in Alzheimer's disease brain.
Experimental neurology 1998;149(2):341-8.
1998: Del-Favero J; Krols L; Michalik A; Theuns J; Löfgren A; Goossens D; Wehnert A; Van den Bossche D; Van Zand K; Backhovens H; van Regenmorter N; Martin J J; Van Broeckhoven C
Molecular genetic analysis of autosomal dominant cerebellar ataxia with retinal degeneration (ADCA type II) caused by CAG triplet repeat expansion.
Human molecular genetics 1998;7(2):177-86.
1998: Marfany G; Del-Favero J; Valero R; De Jonghe C; Woodrow S; Hendriks L; Van Broeckhoven C; Gonzàlez-Duarte R
Identification of a Drosophila presenilin homologue: evidence of alternatively spliced forms.
Journal of neurogenetics 1998;12(1):41-54.
1998: Monsieurs K G; Van Broeckhoven C; Martin J J; Van Hoof V O; Heytens L
Gly341Arg mutation indicating malignant hyperthermia susceptibility: specific cause of chronically elevated serum creatine kinase activity.
Journal of the neurological sciences 1998;154(1):62-5.
1998: Stögbauer F; Young P; Kuhlenbäumer G; Meuleman J; Timmerman V; van Broeckhoven C; Kurlemann G; Ringelstein E B
[Hereditary neural amyotrophy (HNA): clinical and molecular genetic basis]
Fortschritte der Neurologie-Psychiatrie 1998;66(1):10-4.
1998: Rautenstrauss B; Fuchs C; Ekici A; Nelis E; Van Broeckhoven C; Liehr T
Assay of transfection rate in insect cells on a single cell level.
Genetic analysis : biomolecular engineering 1998;14(3):103-4.
1998: Michels-Rautenstrauss K G; Mardin C Y; Budde W M; Liehr T; Polansky J; Nguyen T; Timmerman V; Van Broeckhoven C; Naumann G O; Pfeiffer R A; Rautenstrauss B W
Juvenile open angle glaucoma: fine mapping of the TIGR gene to 1q24.3-q25.2 and mutation analysis.
Human genetics 1998;102(1):103-6.
1998: Stögbauer F; Young P; Wiebusch H; Timmerman V; Kuhlenbäumer G; Nelis E; Ringelstein E B; Kurlemann G; Assmann G; Van Broeckhoven C; Funke H
Absence of mutations in peripheral myelin protein-22, myelin protein zero, and connexin 32 in autosomal recessive Dejerine-Sottas syndrome.
Neuroscience letters 1998;240(1):1-4.
1998: Tysoe C; Whittaker J; Xuereb J; Cairns N J; Cruts M; Van Broeckhoven C; Wilcock G; Rubinsztein D C
A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease.
American journal of human genetics 1998;62(1):70-6.
1998: Cruts M; van Duijn C M; Backhovens H; Van den Broeck M; Wehnert A; Serneels S; Sherrington R; Hutton M; Hardy J; St George-Hyslop P H; Hofman A; Van Broeckhoven C
Estimation of the genetic contribution of presenilin-1 and -2 mutations in a population-based study of presenile Alzheimer disease.
Human molecular genetics 1998;7(1):43-51.
1998: Besançon R; Lorenzi A; Cruts M; Radawiec S; Sturtz F; Broussolle E; Chazot G; van Broeckhoven C; Chamba G; Vandenberghe A
Missense mutation in exon 11 (Codon 378) of the presenilin-1 gene in a French family with early-onset Alzheimer's disease and transmission study by mismatch enhanced allele specific amplification. Mutations in brief no. 141. Online. besancon@rockefeller1.univ.lyon1.fr.
Human mutation 1998;11(6):481.
1998: Van Broeckhoven C
Alzheimer's disease: identification of genes and genetic risk factors.
Progress in brain research 1998;117():315-25.
1998: Slooter A J; van Duijn C M; Bots M L; Ott A; Breteler M B; De Voecht J; Wehnert A; de Knijff P; Havekes L M; Grobbee D E; Van Broeckhoven C; Hofman A
Apolipoprotein E genotype, atherosclerosis, and cognitive decline: the Rotterdam Study.
Journal of neural transmission. Supplementum 1998;53():17-29.
1998: Van Broeckhoven C; Verheyen G
Chromosome 18 workshop.
Psychiatric genetics 1998;8(2):97-108.
1998: Cruts M; Van Broeckhoven C
Presenilin mutations in Alzheimer's disease.
Human mutation 1998;11(3):183-90.
1997: Bornebroek M; Westendorp R G; Haan J; Bakker E; Timmers W F; Van Broeckhoven C; Roos R A
Mortality from hereditary cerebral haemorrhage with amyloidosis--Dutch type. The impact of sex, parental transmission and year of birth.
Brain : a journal of neurology 1997;120 ( Pt 12)():2243-9.
1997: Mendlewicz J; Lindbald K; Souery D; Mahieu B; Nylander P O; De Bruyn A; Zander C; Engström C; Adolfsson R; Van Broeckhoven C; Schalling M; Lipp O
Expanded trinucleotide CAG repeats in families with bipolar affective disorder.
Biological psychiatry 1997;42(12):1115-22.
1997: Okochi M; Ishii K; Usami M; Sahara N; Kametani F; Tanaka K; Fraser P E; Ikeda M; Saunders A M; Hendriks L; Shoji S I; Nee L E; Martin J J; Van Broeckhoven C; St George-Hyslop P H; Roses A D; Mori H
Proteolytic processing of presenilin-1 (PS-1) is not associated with Alzheimer's disease with or without PS-1 mutations.
FEBS letters 1997;418(1-2):162-6.
1997: Marichal P; Vanden Bossche H; Odds F C; Nobels G; Warnock D W; Timmerman V; Van Broeckhoven C; Fay S; Mose-Larsen P
Molecular biological characterization of an azole-resistant Candida glabrata isolate.
Antimicrobial agents and chemotherapy 1997;41(10):2229-37.
1997: Oruc L; Verheyen G R; Furac I; Jakovljevic M; Ivezic S; Raeymaekers P; Van Broeckhoven C
Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder.
American journal of medical genetics 1997;74(5):504-6.
1997: Orti R; Mégarbane A; Maunoury C; Van Broeckhoven C; Sinet P M; Delabar J M
High-resolution physical mapping of a 6.7-Mb YAC contig spanning a region critical for the monosomy 21 phenotype in 21q21.3-q22.1.
Genomics 1997;43(1):25-33.
1997: Bornebroek M; Haan J; Backhovens H; Deutz P; Van Buchem M A; van den Broeck M; Bakker E; Roos R A; Van Broeckhoven C
Presenilin-1 polymorphism and hereditary cerebral hemorrhage with amyloidosis, Dutch type.
Annals of neurology 1997;42(1):108-10.
1997: De Jonghe P; Timmerman V; FitzPatrick D; Spoelders P; Martin J J; Van Broeckhoven C
Mutilating neuropathic ulcerations in a chromosome 3q13-q22 linked Charcot-Marie-Tooth disease type 2B family.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):570-3.
1997: Wehnert M; Timmerman V; Spoelders P; Meuleman J; Nelis E; Van Broeckhoven C
Further evidence supporting linkage of hereditary neuralgic amyotrophy to chromosome 17q.
Neurology 1997;48(6):1719-21.
1997: Stevens M; van Duijn C M; de Knijff P; van Broeckhoven C; Heutink P; Oostra B A; Niermeijer M F; van Swieten J C
Apolipoprotein E gene and sporadic frontal lobe dementia.
Neurology 1997;48(6):1526-9.
1997: Bort S; Nelis E; Timmerman V; Sevilla T; Cruz-Martínez A; Martínez F; Millán J M; Arpa J; Vílchez J J; Prieto F; Van Broeckhoven C; Palau F
Mutational analysis of the MPZ, PMP22 and Cx32 genes in patients of Spanish ancestry with Charcot-Marie-Tooth disease and hereditary neuropathy with liability to pressure palsies.
Human genetics 1997;99(6):746-54.
1997: Robinson R L; Monnier N; Wolz W; Jung M; Reis A; Nuernberg G; Curran J L; Monsieurs K; Stieglitz P; Heytens L; Fricker R; van Broeckhoven C; Deufel T; Hopkins P M; Lunardi J; Mueller C R
A genome wide search for susceptibility loci in three European malignant hyperthermia pedigrees.
Human molecular genetics 1997;6(6):953-61.
1997: Mahieu B; Souery D; Lipp O; Mendelbaum K; Verheyen G; De Maertelaer V; Van Broeckhoven C; Mendlewicz J
No association between bipolar affective disorder and a serotonin receptor (5-HT2A) polymorphism.
Psychiatry research 1997;70(2):65-9.
1997: Hendriks L; Thinakaran G; Harris C L; De Jonghe C; Martin J J; Sisodia S S; Van Broeckhoven C
Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.
Neuroreport 1997;8(7):1717-21.
1997: Claes S; Raeymaekers P; Van den Broeck M; Diependaele S; De bruyn A; Verheyen G; Wils V; Boogaerts A; Tanghe A; Godderis J; Van Broeckhoven C; Cassiman J J
A chromosome 18 genetic linkage study in three large Belgian pedigrees with bipolar disorder.
Journal of affective disorders 1997;43(3):195-205.
1997: Ezquerra M; Blesa R; Tolosa E; Lopez Pousa S; Aguilar M; Peña J; Van Broeckhoven C; Ballesta F; Oliva R
The genotype 2/2 of the presenilin-1 polymorphism is decreased in Spanish early-onset Alzheimer's disease.
Neuroscience letters 1997;227(3):201-4.
1997: Bornebroek M; Haan J; Van Duinen S G; Maat-Schieman M L; Van Buchem M A; Bakker E; Van Broeckhoven C; Roos R A
Dutch hereditary cerebral amyloid angiopathy: structural lesions and apolipoprotein E genotype.
Annals of neurology 1997;41(5):695-8.
1997: Stögbauer F; Young P; Timmerman V; Spoelders P; Ringelstein E B; Van Broeckhoven C; Kurlemann G
Refinement of the hereditary neuralgic amyotrophy (HNA) locus to chromosome 17q24-q25.
Human genetics 1997;99(5):685-7.
1997: Oruc L; Verheyen G R; Furac I; Jakovljevic M; Ivezic S; Raeymaekers P; Van Broeckhoven C
Analysis of the tyrosine hydroxylase and dopamine D4 receptor genes in a Croatian sample of bipolar I and unipolar patients.
American journal of medical genetics 1997;74(2):176-8.
1997: Slooter A J; Tang M X; van Duijn C M; Stern Y; Ott A; Bell K; Breteler M M; Van Broeckhoven C; Tatemichi T K; Tycko B; Hofman A; Mayeux R
Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.
JAMA : the journal of the American Medical Association 1997;277(10):818-21.
1997: Oruc L; Lindblad K; Verheyen G R; Ahlberg S; Jakovljevic M; Ivezic S; Raeymaekers P; Van Broeckhoven C; Schalling M
CAG repeat expansions in bipolar and unipolar disorders.
American journal of human genetics 1997;60(3):730-2.
1997: Beuten J; De Vriendt E; De Jonghe P; Martin J J; Van Broeckhoven C; Timmerman V
Mutation analysis of the human pancreatic phospholipase A2 gene in a family with distal hereditary motor neuropathy type II linked to 12q24.
Neuroscience letters 1997;223(1):69-71.
1997: Krols L; Martin J J; David G; Van Regemorter N; Benomar A; Löfgren A; Stevanin G; Dürr A; Brice A; Van Broeckhoven C
Refinement of the locus for autosomal dominant cerebellar ataxia type II to chromosome 3p21.1-14.1.
Human genetics 1997;99(2):225-32.
1997: Hofman A; Ott A; Breteler M M; Bots M L; Slooter A J; van Harskamp F; van Duijn C N; Van Broeckhoven C; Grobbee D E
Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study.
Lancet 1997;349(9046):151-4.
1997: Kumar-Singh S; Segers K; Rodeck U; Backhovens H; Bogers J; Weyler J; Van Broeckhoven C; Van Marck E
WT1 mutation in malignant mesothelioma and WT1 immunoreactivity in relation to p53 and growth factor receptor expression, cell-type transition, and prognosis.
The Journal of pathology 1997;181(1):67-74.
1997: Timmerman V; Rautenstrauss B; Reiter L T; Koeuth T; Löfgren A; Liehr T; Nelis E; Bathke K D; De Jonghe P; Grehl H; Martin J J; Lupski J R; Van Broeckhoven C
Detection of the CMT1A/HNPP recombination hotspot in unrelated patients of European descent.
Journal of medical genetics 1997;34(1):43-9.
1997: Nelis E; Holmberg B; Adolfsson R; Holmgren G; van Broeckhoven C
PMP22 Thr(118)Met: recessive CMT1 mutation or polymorphism?
Nature genetics 1997;15(1):13-4.
1997: De Jonghe P; Timmerman V; Nelis E; Martin J J; Van Broeckhoven C
Charcot-Marie-Tooth disease and related peripheral neuropathies.
Journal of the peripheral nervous system : JPNS 1997;2(4):370-87.
1997: Korenberg J R; Aaltonen J; Brahe C; Cabin D; Creau N; Delabar J M; Doering J; Gardiner K; Hubert R S; Ives J; Kessling A; Kudoh J; Lafrenière R; Murakami Y; Ohira M; Ohki M; Patterson D; Potier M C; Quackenbush J; Reeves R H; Sakaki Y; Shimizu N; Soeda E; Van Broeckhoven C; Yaspo M L
Report and abstracts of the Sixth International Workshop on Human Chromosome 21 Mapping 1996. Cold Spring Harbor, New York, USA. May 6-8,1996.
Cytogenetics and cell genetics 1997;79(1-2):21-52.
1997: Müller H W; Suter U; Van Broeckhoven C; Hanemann C O; Nelis E; Timmerman V; Sancho S; Barrio L; Bolhuis P; Dermietzel R; Frank M; Gabreëls-Festen A; Gillen C; Haites N; Levi G; Mariman E; Martini R; Nave K; Rautenstrauss B; Schachner M; Schenone A; Schneider C; Schröder M; Willecke K;
Advances in Charcot-Marie-Tooth disease research: cellular function of CMT-related proteins, transgenic animal models, and pathomechanisms. The European CMT Consortium.
Neurobiology of disease 1997;4(3-4):215-20.
1997: Oruc L; Verheyen G R; Furac I; Ivezic S; Jakovljevic M; Raeymaekers P; Van Broeckhoven C
Positive association between the GABRA5 gene and unipolar recurrent major depression.
Neuropsychobiology 1997;36(2):62-4.
1997: Nelis E; Simokovic S; Timmerman V; Löfgren A; Backhovens H; De Jonghe P; Martin J J; Van Broeckhoven C
Mutation analysis of the connexin 32 (Cx32) gene in Charcot-Marie-Tooth neuropathy type 1: identification of five new mutations.
Human mutation 1997;9(1):47-52.
1996: Souery D; Lipp O; Mahieu B; Mendelbaum K; De Martelaer V; Van Broeckhoven C; Mendlewicz J
Association study of bipolar disorder with candidate genes involved in catecholamine neurotransmission: DRD2, DRD3, DAT1, and TH genes.
American journal of medical genetics 1996;67(6):551-5.
1996: Chapon F; Diraison P; Lechevalier B; Chazot G; Viader F; Bonnebouche C; Vandenberghe A; Timmerman V; Van Broeckhoven C; Vandenberghe A
Hereditary neuropathy with liability to pressure palsies with a partial deletion of the region often duplicated in Charcot-Marie-Tooth disease, type 1A.
Journal of neurology, neurosurgery, and psychiatry 1996;61(5):535-6.
1996: Monsieurs K G; Van Broeckhoven C; Martin J J; Dehaene I; Heytens L G
Malignant hyperthermia susceptibility in a patient with concomitant motor neuron disease.
Journal of the neurological sciences 1996;142(1-2):36-8.
1996: Warner L E; Hilz M J; Appel S H; Killian J M; Kolodry E H; Karpati G; Carpenter S; Watters G V; Wheeler C; Witt D; Bodell A; Nelis E; Van Broeckhoven C; Lupski J R
Clinical phenotypes of different MPZ (P0) mutations may include Charcot-Marie-Tooth type 1B, Dejerine-Sottas, and congenital hypomyelination.
Neuron 1996;17(3):451-60.
1996: Gabreëls-Festen A A; Hoogendijk J E; Meijerink P H; Gabreëls F J; Bolhuis P A; van Beersum S; Kulkens T; Nelis E; Jennekens F G; de Visser M; van Engelen B G; Van Broeckhoven C; Mariman E C
Two divergent types of nerve pathology in patients with different P0 mutations in Charcot-Marie-Tooth disease.
Neurology 1996;47(3):761-5.
1996: Rao V S; Cupples A; van Duijn C M; Kurz A; Green R C; Chui H; Duara R; Auerbach S A; Volicer L; Wells J; van Broeckhoven C; Growdon J H; Haines J L; Farrer L A
Evidence for major gene inheritance of Alzheimer disease in families of patients with and without apolipoprotein E epsilon 4.
American journal of human genetics 1996;59(3):664-75.
1996: Souery D; Lipp O; Mahieu B; Mendelbaum K; De Bruyn A; De Maertelaer V; Van Broeckhoven C; Mendlewicz J
Excess tyrosine hydroxylase restriction fragment length polymorphism homozygosity in unipolar but not bipolar patients: a preliminary report.
Biological psychiatry 1996;40(4):305-8.
1996: Slooter A J; Breteler M B; Ott A; Van Broeckhoven C; van Duijn C M
APOE genotyping in differential diagnosis of Alzheimer's disease.
Lancet 1996;348(9023):334.
1996: Timmerman V; De Jonghe P; Simokovic S; Löfgren A; Beuten J; Nelis E; Ceuterick C; Martin J J; Van Broeckhoven C
Distal hereditary motor neuropathy type II (distal HMN II): mapping of a locus to chromosome 12q24.
Human molecular genetics 1996;5(7):1065-9.
1996: Bronzova J; van Duijn C M; Havekes L M; de Knijff P; Van Broeckhoven C; Hofman A
Apolipoprotein E genotype and concomitant clinical features in early-onset Alzheimer's disease.
Journal of neurology 1996;243(6):465-8.
1996: Villanova M; Malandrini A; Biancotti R; Löfgren A; Mongini T; Six J; Salvestroni R; Parrotta E; Van Broeckhoven C; Paolozzi C; Guazzi G
Muscular dystrophy, mental retardation and cardiomyopathy not associated with dystrophin deficiency.
Neuromuscular disorders : NMD 1996;6(3):167-72.
1996: Quattrone A; Gambardella A; Bono F; Aguglia U; Bolino A; Bruni A C; Montesi M P; Oliveri R L; Sabatelli M; Tamburrini O; Valentino P; Van Broeckhoven C; Zappia M
Autosomal recessive hereditary motor and sensory neuropathy with focally folded myelin sheaths: clinical, electrophysiologic, and genetic aspects of a large family.
Neurology 1996;46(5):1318-24.
1996: Timmerman V; De Jonghe P; Spoelders P; Simokovic S; Löfgren A; Nelis E; Vance J; Martin J J; Van Broeckhoven C
Linkage and mutation analysis of Charcot-Marie-Tooth neuropathy type 2 families with chromosomes 1p35-p36 and Xq13.
Neurology 1996;46(5):1311-8.
1996: De bruyn A; Souery D; Mendelbaum K; Mendlewicz J; Van Broeckhoven C
Linkage analysis of families with bipolar illness and chromosome 18 markers.
Biological psychiatry 1996;39(8):679-88.
1996: Hendriks L; Van Broeckhoven C
A beta A4 amyloid precursor protein gene and Alzheimer's disease.
European journal of biochemistry / FEBS 1996;237(1):6-15.
1996: Timmerman V; Löfgren A; Le Guern E; Liang P; De Jonghe P; Martin J J; Verhalle D; Robberecht W; Gouider R; Brice A; Van Broeckhoven C
Molecular genetic analysis of the 17p11.2 region in patients with hereditary neuropathy with liability to pressure palsies (HNPP).
Human genetics 1996;97(1):26-34.
1996: Oruc L; Furac I; Croux C; Jakovljevic M; Kracun I; Folnegovic V; Van Broeckhoven C
Association study between bipolar disorder and candidate genes involved in dopamine-serotonin metabolism and GABAergic neurotransmission: a preliminary report.
Psychiatric genetics 1996;6(4):213-7.
1996: Nelis E; Warner L E; Vriendt E D; Chance P F; Lupski J R; Van Broeckhoven C
Comparison of single-strand conformation polymorphism and heteroduplex analysis for detection of mutations in Charcot-Marie-Tooth type 1 disease and related peripheral neuropathies.
European journal of human genetics : EJHG 1996;4(6):329-33.
1996: Silander K; Meretoja P; Nelis E; Timmerman V; Van Broeckhoven C; Aula P; Savontaus M L
A de novo duplication in 17p11.2 and a novel mutation in the Po gene in two Déjérine-Sottas syndrome patients.
Human mutation 1996;8(4):304-10.
1996: De Jonghe P; Krols L; Michalik A; Hazan J; Smeyers G; Löfgren A; Weissenbach J; Martin J J; Van Broeckhoven C
Pure familial spastic paraplegia: clinical and genetic analysis of nine Belgian pedigrees.
European journal of human genetics : EJHG 1996;4(5):260-6.
1996: Hendriks L; Jonghe CDXs; Cras P; Martin J J; Broeckhoven C V
Beta-amyloid precursor protein and early-onset Alzheimer's disease.
Ciba Foundation symposium 1996;199():170-80.
1996: Cruts M; Hendriks L; Van Broeckhoven C
The presenilin genes: a new gene family involved in Alzheimer disease pathology.
Human molecular genetics 1996;5 Spec No():1449-55.
1996: De bruyn A; Souery D; Mendelbaum K; Mendlewicz J; Van Broeckhoven C
A linkage study between bipolar disorder and genes involved in dopaminergic and GABAergic neurotransmission.
Psychiatric genetics 1996;6(2):67-73.
1996: Nelis E; Van Broeckhoven C; De Jonghe P; Löfgren A; Vandenberghe A; Latour P; Le Guern E; Brice A; Mostacciuolo M L; Schiavon F; Palau F; Bort S; Upadhyaya M; Rocchi M; Archidiacono N; Mandich P; Bellone E; Silander K; Savontaus M L; Navon R; Goldberg-Stern H; Estivill X; Volpini V; Friedl W; Gal A
Estimation of the mutation frequencies in Charcot-Marie-Tooth disease type 1 and hereditary neuropathy with liability to pressure palsies: a European collaborative study.
European journal of human genetics : EJHG 1996;4(1):25-33.
1996: Bellone E; Mandich P; James R; Nelis E; Lamba L D; Van Broeckhoven C; Ajmar F
Identification of a 4 bp deletion (1560del4) in po gene in a family with severe Charcot-Marie-Tooth disease.
Human mutation 1996;7(4):377-8.
1995: Van Broeckhoven C
Presenilins and Alzheimer disease.
Nature genetics 1995;11(3):230-2.
1995: Brooks W S; Martins R N; De Voecht J; Nicholson G A; Schofield P R; Kwok J B; Fisher C; Yeung L U; Van Broeckhoven C
A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease.
Neuroscience letters 1995;199(3):183-6.
1995: Cruts M; Backhovens H; Theuns J; Clark R F; Le Paslier D; Weissenbach J; Goate A M; Martin J J; Van Broeckhoven C
Genetic and physical characterization of the early-onset Alzheimer's disease AD3 locus on chromosome 14q24.3.
Human molecular genetics 1995;4(8):1355-64.
1995: Clark R F; Cruts M; Korenblat K M; He C; Talbot C; Van Broeckhoven C; Goate A M
A yeast artificial chromosome contig from human chromosome 14q24 spanning the Alzheimer's disease locus AD3.
Human molecular genetics 1995;4(8):1347-54.
1995: Navon R; Timmerman V; Löfgren A; Liang P; Nelis E; Zeitune M; Van Broeckhoven C
Prenatal diagnosis of Charcot-Marie-Tooth disease type 1A (CMT1A) using molecular genetic techniques.
Prenatal diagnosis 1995;15(7):633-40.
1995: James R; Bellone E; Nelis E; Mandich P; Schenone A; Mancardi G; Van Broeckhoven C; Abbruzzese M; Ajmar F
Molecular analysis of three cases with hereditary motor and sensory neuropathy with myelin outfolding.
Neuroscience letters 1995;194(1-2):136-8.
1995: van Duijn C M; de Knijff P; Wehnert A; De Voecht J; Bronzova J B; Havekes L M; Hofman A; Van Broeckhoven C
The apolipoprotein E epsilon 2 allele is associated with an increased risk of early-onset Alzheimer's disease and a reduced survival.
Annals of neurology 1995;37(5):605-10.
1995: Liu J; Lissens W; Van Broeckhoven C; Löfgren A; Camus M; Liebaers I; Van Steirteghem A
Normal pregnancy after preimplantation DNA diagnosis of a dystrophin gene deletion.
Prenatal diagnosis 1995;15(4):351-8.
1995: Sudbrak R; Procaccio V; Klausnitzer M; Curran J L; Monsieurs K; van Broeckhoven C; Ellis R; Heyetens L; Hartung E J; Kozak-Ribbens G
Mapping of a further malignant hyperthermia susceptibility locus to chromosome 3q13.1.
American journal of human genetics 1995;56(3):684-91.
1995: van Duijn C M; Havekes L M; Van Broeckhoven C; de Knijff P; Hofman A
Apolipoprotein E genotype and association between smoking and early onset Alzheimer's disease.
BMJ (Clinical research ed.) 1995;310(6980):627-31.
1995: Gosset P; Crété N; Ait Ghezala G; Théophile D; Van Broeckhoven C; Vayssettes C; Sinet P M; Créau N
A high-resolution map of 1.6 Mb in the Down syndrome region: a new map between D21S55 and ETS2.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(2):127-30.
1995: Segers K; Backhovens H; Singh S K; De Voecht J; Ramael M; Van Broeckhoven C; Van Marck E
Immunoreactivity for p53 and mdm2 and the detection of p53 mutations in human malignant mesothelioma.
Virchows Archiv : an international journal of pathology 1995;427(4):431-6.
1995: Mendelbaum K; Sevy S; Souery D; Papadimitriou G N; De Bruyn A; Raeymaekers P; Van Broeckhoven C; Mendlewicz J
Manic-depressive illness and linkage reanalysis in the Xq27-Xq28 region of chromosome X.
Neuropsychobiology 1995;31(2):58-63.
1995: Van Broeckhoven C L
Molecular genetics of Alzheimer disease: identification of genes and gene mutations.
European neurology 1995;35(1):8-19.
1994: De bruyn A; Raeymaekers P; Mendelbaum K; Sandkuijl L A; Raes G; Delvenne V; Hirsch D; Staner L; Mendlewicz J; Van Broeckhoven C
Linkage analysis of bipolar illness with X-chromosome DNA markers: a susceptibility gene in Xq27-q28 cannot be excluded.
American journal of medical genetics 1994;54(4):411-9.
1994: Nelis E; Timmerman V; De Jonghe P; Vandenberghe A; Pham-Dinh D; Dautigny A; Martin J J; Van Broeckhoven C
Rapid screening of myelin genes in CMT1 patients by SSCP analysis: identification of new mutations and polymorphisms in the P0 gene.
Human genetics 1994;94(6):653-7.
1994: Vanhoof G; Goossens F; Hendriks L; De Meester I; Hendriks D; Vriend G; Van Broeckhoven C; Scharpé S
Cloning and sequence analysis of the gene encoding human lymphocyte prolyl endopeptidase.
Gene 1994;149(2):363-6.
1994: van Duijn C M; Hendriks L; Farrer L A; Backhovens H; Cruts M; Wehnert A; Hofman A; Van Broeckhoven C
A population-based study of familial Alzheimer disease: linkage to chromosomes 14, 19, and 21.
American journal of human genetics 1994;55(4):714-27.
1994: Nelis E; Timmerman V; De Jonghe P; Muylle L; Martin J J; Van Broeckhoven C
Linkage and mutation analysis in an extended family with Charcot-Marie-Tooth disease type 1B.
Journal of medical genetics 1994;31(10):811-5.
1994: Haan J; Van Broeckhoven C; van Duijn C M; Voorhoeve E; van Harskamp F; van Swieten J C; Maat-Schieman M L; Roos R A; Bakker E
The apolipoprotein E epsilon 4 allele does not influence the clinical expression of the amyloid precursor protein gene codon 693 or 692 mutations.
Annals of neurology 1994;36(3):434-7.
1994: Rautenstrauss B; Nelis E; Grehl H; Pfeiffer R A; Van Broeckhoven C
Identification of a de novo insertional mutation in P0 in a patient with a Déjérine-Sottas syndrome (DSS) phenotype.
Human molecular genetics 1994;3(9):1701-2.
1994: Dutriaux A; Rossier J; Van Hul W; Nizetic D; Theophille D; Delabar J M; Van Broeckhoven C; Potier M C
Cloning and characterization of a 135- to 500-kb region of homology on the long arm of human chromosome 21.
Genomics 1994;22(2):472-7.
1994: Verhalle D; Löfgren A; Nelis E; Dehaene I; Theys P; Lammens M; Dom R; Van Broeckhoven C; Robberecht W
Deletion in the CMT1A locus on chromosome 17p11.2 in hereditary neuropathy with liability to pressure palsies.
Annals of neurology 1994;35(6):704-8.
1994: Matise T C; Chakravarti A; Patel P I; Lupski J R; Nelis E; Timmerman V; Van Broeckhoven C; Weeks D E
Detection of tandem duplications and implications for linkage analysis.
American journal of human genetics 1994;54(6):1110-21.
1994: Holmberg B H; Holmgren G; Nelis E; van Broeckhoven C; Westerberg B
Charcot-Marie-Tooth disease in northern Sweden: pedigree analysis and the presence of the duplication in chromosome 17p11.2.
Journal of medical genetics 1994;31(6):435-41.
1994: Cruts M; Backhovens H; Martin J J; van Broeckhoven C
Genetic analysis of the cellular oncogene fos in patients with chromosome 14 encoded Alzheimer's disease.
Neuroscience letters 1994;174(1):97-100.
1994: van Duijn C M; de Knijff P; Cruts M; Wehnert A; Havekes L M; Hofman A; Van Broeckhoven C
Apolipoprotein E4 allele in a population-based study of early-onset Alzheimer's disease.
Nature genetics 1994;7(1):74-8.
1994: Hanemann C O; Stoll G; D'Urso D; Fricke W; Martin J J; Van Broeckhoven C; Mancardi G L; Bartke I; Müller H W
Peripheral myelin protein-22 expression in Charcot-Marie-Tooth disease type 1a sural nerve biopsies.
Journal of neuroscience research 1994;37(5):654-9.
1994: Van Broeckhoven C; Backhovens H; Cruts M; Martin J J; Crook R; Houlden H; Hardy J
APOE genotype does not modulate age of onset in families with chromosome 14 encoded Alzheimer's disease.
Neuroscience letters 1994;169(1-2):179-80.
1994: Nelis E; Timmerman V; De Jonghe P; Van Broeckhoven C
Identification of a 5' splice site mutation in the PMP-22 gene in autosomal dominant Charcot-Marie-Tooth disease type 1.
Human molecular genetics 1994;3(3):515-6.
1994: De bruyn A; Mendelbaum K; Sandkuijl L A; Delvenne V; Hirsch D; Staner L; Mendlewicz J; Van Broeckhoven C
Nonlinkage of bipolar illness to tyrosine hydroxylase, tyrosinase, and D2 and D4 dopamine receptor genes on chromosome 11.
The American journal of psychiatry 1994;151(1):102-6.
1994: Van Broeckhoven C
Genes in early onset Alzheimer's disease: implications for AD research.
Neurobiology of aging 1994;15 Suppl 2():S149-53.
1993: Palau F; Löfgren A; De Jonghe P; Bort S; Nelis E; Sevilla T; Martin J J; Vilchez J; Prieto F; Van Broeckhoven C
Origin of the de novo duplication in Charcot-Marie-Tooth disease type 1A: unequal nonsister chromatid exchange during spermatogenesis.
Human molecular genetics 1993;2(12):2031-5.
1993: Willems P; Vits L; Buntinx I; Raeymaekers P; Van Broeckhoven C; Ceulemans B
Localization of a gene responsible for nonspecific mental retardation (MRX9) to the pericentromeric region of the X chromosome.
Genomics 1993;18(2):290-4.
1993: Van Hul W; Van Camp G; Stuyver L; Delabar J M; McInnis M G; Warren A C; Antonarakis S E; Van Broeckhoven C
A contiguous physical map of the pericentromeric region of chromosome 21q between D21Z1 and D21S13E.
Genomics 1993;15(3):626-30.
1993: Beuten J; Mangelschots K; Buntinx I; Coucke P; Brouwer O F; Hennekam R C; Van Broeckhoven C; Willems P J
Molecular study of chromosome 15 in 22 patients with Angelman syndrome.
Human genetics 1993;90(5):489-95.
1993: Martin J J; Ceuterick C; Lübke U; Van Broeckhoven C
Duchenne muscular dystrophy immunohistochemistry of foetal muscles.
Acta neurologica Belgica 1993;93(3):130-8.
1992: Van Broeckhoven C; Backhovens H; Cruts M; De Winter G; Bruyland M; Cras P; Martin J J
Mapping of a gene predisposing to early-onset Alzheimer's disease to chromosome 14q24.3.
Nature genetics 1992;2(4):335-9.
1992: Peterson M B; Frantzen M; Antonarakis S E; Warren A C; Van Broeckhoven C; Chakravarti A; Cox T K; Lund C; Olsen B; Poulsen H
Comparative study of microsatellite and cytogenetic markers for detecting the origin of the nondisjoined chromosome 21 in Down syndrome.
American journal of human genetics 1992;51(3):516-25.
1992: Wehnert A; Cruts M; Backhovens H; Delabar J M; Thomas G; Van Broeckhoven C
Dinucleotide repeat polymorphism at the D21S258 locus.
Human molecular genetics 1992;1(6):449.
1992: Willems P J; Vits L; Raeymaekers P; Beuten J; Coucke P; Holden J J; Van Broeckhoven C; Warren S T; Sagi M; Robinson D
Further localization of X-linked hydrocephalus in the chromosomal region Xq28.
American journal of human genetics 1992;51(2):307-15.
1992: Warren A C; Petersen M B; Van Hul W; McInnis M G; Van Broeckhoven C; Cox T K; Chakravarti A; Antonarakis S E
D21S215 is a (GT)n polymorphic marker close to centromeric alphoid sequences on chromosome 21.
Genomics 1992;13(4):1365-7.
1992: Timmerman V; Raeymaekers P; Nelis E; De Jonghe P; Muylle L; Ceuterick C; Martin J J; Van Broeckhoven C
Linkage analysis of distal hereditary motor neuropathy type II (distal HMN II) in a single pedigree.
Journal of the neurological sciences 1992;109(1):41-8.
1992: Hoogendijk J E; Hensels G W; Gabreëls-Festen A A; Gabreëls F J; Janssen E A; de Jonghe P; Martin J J; van Broeckhoven C; Valentijn L J; Baas F
De-novo mutation in hereditary motor and sensory neuropathy type I.
Lancet 1992;339(8801):1081-2.
1992: Uhlhaas S; Bakker E; van Broeckhoven C; Barth-Schulz A; Friedl W
A rare MspI RFLP of the DMD probe p20 (DXS269).
Human genetics 1992;89(1):122.
1992: Cruts M; Backhovens H; Van Broeckhoven C
Dinucleotide repeat polymorphism at the D21S16 [correction of D1S16] locus.
Nucleic acids research 1992;20(5):1159.
1992: Cruts M; Backhovens H; Van Broeckhoven C
Dinucleotide repeat polymorphism at the D21S145 locus.
Nucleic acids research 1992;20(5):1159.
1992: Van Camp G; Cruts M; Backhovens H; Wehnert A; Van Broeckhoven C
Unique sequence homology in the pericentromeric regions of the long arms of chromosomes 13 and 21.
Genomics 1992;12(1):158-60.
1992: van Essen A J; Abbs S; Baiget M; Bakker E; Boileau C; van Broeckhoven C; Bushby K; Clarke A; Claustres M; Covone A E
Parental origin and germline mosaicism of deletions and duplications of the dystrophin gene: a European study.
Human genetics 1992;88(3):249-57.
1992: Raeymaekers P; Timmerman V; Nelis E; Van Hul W; De Jonghe P; Martin J J; Van Broeckhoven C
Estimation of the size of the chromosome 17p11.2 duplication in Charcot-Marie-Tooth neuropathy type 1a (CMT1a). HMSN Collaborative Research Group.
Journal of medical genetics 1992;29(1):5-11.
1992: Martin J J; Leroy J; Ceuterick C; Lübke U; Van Buggenhout E; Van Vuchelen J; Van Broeckhoven C
Becker-type muscular dystrophy. Report of a family with one postmortem study.
Clinical neurology and neurosurgery 1992;94 Suppl():S123-6.
1991: Mendlewicz J; Leboyer M; De Bruyn A; Malafosse A; Sevy S; Hirsch D; Van Broeckhoven C; Mallet J
Absence of linkage between chromosome 11p15 markers and manic-depressive illness in a Belgian pedigree.
The American journal of psychiatry 1991;148(12):1683-7.
1991: Van Camp G; Backhovens H; Cruts M; Wehnert A; Van Hul W; Stinissen P; Van Broeckhoven C
Identification of chromosome 21 DNA polymorphisms for genetic studies in Alzheimer's disease and Down syndrome.
Human genetics 1991;87(6):649-53.
1991: Stinissen P; Van Broeckhoven C
A new (CA)n repeat polymorphism at the D21S13E locus.
Nucleic acids research 1991;19(18):5089.
1991: Bakker E; van Broeckhoven C; Haan J; Voorhoeve E; van Hul W; Levy E; Lieberburg I; Carman M D; van Ommen G J; Frangione B
DNA diagnosis for hereditary cerebral hemorrhage with amyloidosis (Dutch type)
American journal of human genetics 1991;49(3):518-21.
1991: Chartier-Harlin M C; Crawford F; Hamandi K; Mullan M; Goate A; Hardy J; Backhovens H; Martin J J; Broeckhoven C V
Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended pedigrees with early onset Alzheimer's disease.
Neuroscience letters 1991;129(1):134-5.
1991: Blonden L A; Grootscholten P M; den Dunnen J T; Bakker E; Abbs S; Bobrow M; Boehm C; van Broeckhoven C; Baumbach L; Chamberlain J
242 breakpoints in the 200-kb deletion-prone P20 region of the DMD gene are widely spread.
Genomics 1991;10(3):631-9.
1991: Van Hul W; Backhovens H; Van Camp G; Stinissen P; Cruts M; Wehnert A; Van Broeckhoven C
Subregional localization of the chromosome 21 loci D21S24 and D21S26 using physical mapping techniques.
Human genetics 1991;87(2):109-11.
1991: Stinissen P; Van Broeckhoven C
PCR detection of the frequent TaqI RFLP at locus D21S13E.
Nucleic acids research 1991;19(9):2516.
1991: van Duijn C M; van Broeckhoven C; Hardy J A; Goate A M; Rossor M N; Vandenberghe A; Martin J J; Hofman A; Mullan M J
Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease.
The British journal of psychiatry : the journal of mental science 1991;158():471-4.
1991: Mendlewicz J; Sandkuil L A; De Bruyn A; Van Broeckhoven C
X-linkage in bipolar illness.
Biological psychiatry 1991;29(7):730-1.
1991: van Duijn C M; Hendriks L; Cruts M; Hardy J A; Hofman A; Van Broeckhoven C
Amyloid precursor protein gene mutation in early-onset Alzheimer's disease.
Lancet 1991;337(8747):978.
1991: Willems P J; Hendrickx J; Van der Auwera B J; Vits L; Raeymaekers P; Coucke P J; Van den Bergh I; Berger R; Smit G P; Van Broeckhoven C
Mapping of the gene for X-linked liver glycogenosis due to phosphorylase kinase deficiency to human chromosome region Xp22.
Genomics 1991;9(4):565-9.
1991: Roos R A; Haan J; Van Broeckhoven C
Hereditary cerebral hemorrhage with amyloidosis--Dutch type: a congophilic angiopathy. An overview.
Annals of the New York Academy of Sciences 1991;640():155-60.
1990: Timmerman V; Raeymaekers P; De Jonghe P; De Winter G; Swerts L; Jacobs K; Gheuens J; Martin J J; Vandenberghe A; Van Broeckhoven C
Assignment of the Charcot-Marie-Tooth neuropathy type 1 (CMT 1a) gene to 17p11.2-p12.
American journal of human genetics 1990;47(4):680-5.
1990: Willems P J; Dijkstra I; Van der Auwera B J; Vits L; Coucke P; Raeymaekers P; Van Broeckhoven C; Consalez G G; Freeman S B; Warren S T
Assignment of X-linked hydrocephalus to Xq28 by linkage analysis.
Genomics 1990;8(2):367-70.
1990: St George-Hyslop P H; Haines J L; Farrer L A; Polinsky R; Van Broeckhoven C; Goate A; McLachlan D R; Orr H; Bruni A C; Sorbi S
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. FAD Collaborative Study Group.
Nature 1990;347(6289):194-7.
1990: Willems P J; Vits L; Wanders R J; Coucke P J; Van der Auwera B J; Van Elsen A F; Raeymaekers P; Van Broeckhoven C; Schutgens R B; Dacremont G
Linkage of DNA markers at Xq28 to adrenoleukodystrophy and adrenomyeloneuropathy present within the same family.
Archives of neurology 1990;47(6):665-9.
1990: Stinissen P; Vandenberghe A; Van Broeckhoven C
PCR detection of two RFLP's at the D21S13 locus.
Nucleic acids research 1990;18(12):3672.
1990: Van Broeckhoven C; Haan J; Bakker E; Hardy J A; Van Hul W; Wehnert A; Vegter-Van der Vlis M; Roos R A
Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch).
Science (New York, N.Y.) 1990;248(4959):1120-2.
1990: Van Camp G; Vandenberghe A; Van Broeckhoven C
An informative MspI polymorphism detected at the D21S16 locus.
Human genetics 1990;85(1):140.
1990: Van Camp G; Van Hul W; Backhovens H; Stinissen P; Wehnert A; Patterson D; Vandenberghe A; Van Broeckhoven C
Physical mapping of chromosome 21 DNA markers in Alzheimer's disease region using somatic cell hybrids.
Somatic cell and molecular genetics 1990;16(3):241-9.
1990: Stinissen P; Van Hul W; Van Camp G; Backhovens H; Wehnert A; Vandenberghe A; Van Broeckhoven C
The pericentromeric 21 DNA marker pGSM21 (D21S13) contains an expressed HTF island.
Genomics 1990;7(1):119-22.
1990: Stinissen P; Vandenberghe A; Van Broeckhoven C
A high frequency EcoRI RFLP detected at the D21S13 locus.
Nucleic acids research 1990;18(5):1319.
1990: Stinissen P; Van Roy B; Van Camp G; Backhovens H; Partoens P; Wehnert A; Verniers H; Dumon J; Vandenberghe A; Van Broeckhoven C
Study of the origin of nondisjunction in a family with two cases of Down syndrome using cytogenetic and molecular polymorphisms.
American journal of medical genetics. Supplement 1990;7():133-6.
1989: Raeymaekers P; Timmerman V; De Jonghe P; Swerts L; Gheuens J; Martin J J; Muylle L; De Winter G; Vandenberghe A; Van Broeckhoven C
Localization of the mutation in an extended family with Charcot-Marie-Tooth neuropathy (HMSN I).
American journal of human genetics 1989;45(6):953-8.
1989: Den Dunnen J T; Grootscholten P M; Bakker E; Blonden L A; Ginjaar H B; Wapenaar M C; van Paassen H M; van Broeckhoven C; Pearson P L; van Ommen G J
Topography of the Duchenne muscular dystrophy (DMD) gene: FIGE and cDNA analysis of 194 cases reveals 115 deletions and 13 duplications.
American journal of human genetics 1989;45(6):835-47.
1989: Van Broeckhoven C L
Molecular genetic analysis of early onset familial Alzheimer's disease.
Neurobiology of aging 1989;10(5):437-8; discussion 446-8.
1989: Bakker E; Veenema H; Den Dunnen J T; van Broeckhoven C; Grootscholten P M; Bonten E J; van Ommen G J; Pearson P L
Germinal mosaicism increases the recurrence risk for 'new' Duchenne muscular dystrophy mutations.
Journal of medical genetics 1989;26(9):553-9.
1989: Berneman Z N; Raeymaekers P; Vanhoof G; Van Bockstaele D; Ramael M; Peetermans M E; Vandenberghe A; Van Broeckhoven C
DNA fingerprints revealing common and divergent human DNA methylation patterns.
FEBS letters 1989;255(2):226-30.
1989: Van Camp G; Stinissen P; Van Hul W; Backhovens H; Wehnert A; Vandenberge A; Van Broeckhoven C
Selection of human chromosome 21-specific DNA probes for genetic analysis in Alzheimer's dementia and Down syndrome.
Human genetics 1989;83(1):58-60.
1989: Raeymaekers P; De Jonghe P; Backhovens H; Wehnert A; De Winter G; Swerts L; Gheuens J; Martin J J; Vandenberghe A; Van Broeckhoven C
Absence of genetic linkage of Charcot-Marie-Tooth disease (HMSN Ia) with chromosome 1 gene markers.
Neurology 1989;39(6):844-6.
1989: Van Camp G; Stinissen P; Vandenberghe A; Van Broeckhoven C
A polymorphic locus [D21S144] is detected by probe pVC12 on chromosome 21.
Nucleic acids research 1989;17(11):4420.
1989: Vandenberghe A; Van Broeckhoven C
[Genetic findings in degenerative dementia]
Acta neurologica Belgica 1989;89(3-4):194-7.
1989: Vandenberghe A; Van Broeckhoven C
[Genetic coupling study using DNA markers in the familial form of Alzheimer's disease]
Acta neurologica Belgica 1989;89(3-4):300-1.
1989: Raeymaekers P; Van Broeckhoven C; Backhovens H; Wehnert A; Muylle L; De Jonghe P; Gheuens J; Martin J J; Vandenberghe A
Linkage analysis of the Duffy blood group marker with several chromosome 1 genes in an extended pedigree with Charcot-Marie-Tooth disease.
Human genetics 1989;81(3):231-3.
1989: Raeymaekers P; Van Broeckhoven C; Vandenberghe A
A polymorphic locus [D1S88] is detected by probe LA01.41 on chromosome 1p.
Nucleic acids research 1989;17(3):1278.
1989: Raeymaekers P; De Jonghe P; Swerts L; De Winter G; Gheuens J; Martin J J; Vandenberghe A; Van Broeckhoven C
Exclusion analysis of Charcot-Marie-Tooth neuropathy (CMT1) with chromosome 1p markers.
Cytogenetics and cell genetics 1989;50(2-3):178-80.
1988: Raeymaekers P; De Jonghe P; Swerts L; Muylle L; Gheuens J; Martin J J; Van Broeckhoven C; Vandenberghe A
Absence of linkage with the Duffy blood group in a family with Charcot-Marie-Tooth neuropathy.
Journal of the neurological sciences 1988;88(1-3):145-50.
1988: Hendriks L; Van Broeckhoven C; Vandenberghe A; Van de Peer Y; De Wachter R
Primary and secondary structure of the 18S ribosomal RNA of the bird spider Eurypelma californica and evolutionary relationships among eukaryotic phyla.
European journal of biochemistry / FEBS 1988;177(1):15-20.
1988: Raeymaekers P; Van Broeckhoven C; Vandenberghe A
A highly polymorphic locus is detected by probe CARLP II6.3 [D5S88]
Nucleic acids research 1988;16(16):8196.
1988: Hendriks L; De Baere R; Van Broeckhoven C; De Wachter R
Primary and secondary structure of the 18 S ribosomal RNA of the insect species Tenebrio molitor.
FEBS letters 1988;232(1):115-20.
1988: Raeymaekers P; Van Broeckhoven C; Vandenberghe A
Two polymorphic loci are detected simultaneously by probe CARLP II8.2 [D10S21] on chromosome 10.
Nucleic acids research 1988;16(6):2738.
1988: Raeymaekers P; Van Broeckhoven C; Backhovens H; Wehnert A; Muylle L; De Jonghe P; Gheuens J; Vandenberghe A
The Duffy blood group is linked to the alpha-spectrin locus in a large pedigree with autosomal dominant inheritance of Charcot-Marie-Tooth disease type 1.
Human genetics 1988;78(1):76-8.
1987: Bakker E; Van Broeckhoven C; Bonten E J; van de Vooren M J; Veenema H; Van Hul W; Van Ommen G J; Vandenberghe A; Pearson P L
Germline mosaicism and Duchenne muscular dystrophy mutations.
Nature 1987;329(6139):554-6.
1987: Van Broeckhoven C; Genthe A M; Vandenberghe A; Horsthemke B; Backhovens H; Raeymaekers P; Van Hul W; Wehnert A; Gheuens J; Cras P
Failure of familial Alzheimer's disease to segregate with the A4-amyloid gene in several European families.
Nature 1987;329(6135):153-5.
1984: Nelles L; Van Broeckhoven C; De Wachter R; Vandenberghe A
Location of the hidden break in large subunit ribosomal RNA of Artemia salina.
Die Naturwissenschaften 1984;71(12):634-5.
1984: Adriaenssens K; Karcher D; Marescau B; Van Broeckhoven C; Lowenthal A; Terheggen H C
Hyperargininemia: the rat as a model for the human disease and the comparative response to enzyme replacement therapy with free arginase and arginase-loaded erythrocytes in vivo.
The International journal of biochemistry 1984;16(7):779-86.
1979: Vandenberghe A; Van Broeckhoven C; De Wachter R
Separation of oligoribonucleotides by high performance liquid chromatography [proceedings]
Archives internationales de physiologie et de biochimie 1979;87(4):848-9.
1978: Van Broeckhoven C; De Wachter R
The reactions of mercurated pyrimidine nucleotides with thiols and with hydrogen sulfide.
Nucleic acids research 1978;5(6):2133-51.
1977: Van Broeckhoven C; De Wachter R
Synthesis and properties of 5-thiomercuri derivatives of pyrimidine nucleotides [proceedings].
Archives internationales de physiologie et de biochimie 1977;85(1):200-1.

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Christine Van Broeckhoven

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