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Ling Liu; Ji Zhang; Jifeng Zhang; Zhou Zhou; Yanbo Fan; Mingui Fu; Yanhong Guo; Shengping Huang; Chen Lab
Zc3h12c inhibits vascular inflammation by repressing NF-κB activation and pro-inflammatory gene expression in endothelial cells.
Luis Villacorta; Jifeng Zhang; Harald Carlsen; Lin Chang; Bruce A Freeman; Tomonaga Ichikawa; Lingyun Jia; Danica Petrovic-Djergovic; Sonia R Salvatore; Francisco J Schopfer; Chen Lab
Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts.
Yanhong Guo; Jiandie D Lin; Jifeng Zhang; Chen Lab; Yanbo Fan; Y Eugene Chen
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.

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All Publications

2013: Ling Liu; Ji Zhang; Jifeng Zhang; Zhou Zhou; Yanbo Fan; Mingui Fu; Yanhong Guo; Shengping Huang; Chen Lab
Zc3h12c inhibits vascular inflammation by repressing NF-κB activation and pro-inflammatory gene expression in endothelial cells.
The Biochemical journal 2013;451(1):55-60.
2013: Luis Villacorta; Jifeng Zhang; Harald Carlsen; Lin Chang; Bruce A Freeman; Tomonaga Ichikawa; Lingyun Jia; Danica Petrovic-Djergovic; Sonia R Salvatore; Francisco J Schopfer; Chen Lab
Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts.
Cardiovascular research 2013;98(1):116-24.
2013: Yanhong Guo; Jiandie D Lin; Jifeng Zhang; Chen Lab; Yanbo Fan; Y Eugene Chen
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β) protein attenuates vascular lesion formation by inhibition of chromatin loading of minichromosome maintenance complex in smooth muscle cells.
The Journal of biological chemistry 2013;288(7):4625-36.
2013: Yao Wang; Ahmed Bilal Waqar; Teruo Watanabe; Tomohiro Yoshikawa; Ying Yu; Xiaohui Zha; Jifeng Zhang; Yujiro Asada; Chen Lab; Tomohiro Inoue; Yuka Keyamura; Shuji Kitajima; Masayuki Kohashi; Tomonari Koike; Enqi Liu; Loretta Ma; Manabu Niimi; Kazutoshi Nishijima; Jianglin Fan
Human apolipoprotein A-II protects against diet-induced atherosclerosis in transgenic rabbits.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(2):224-31.
2013: Jifeng Zhang; Yuan Zhang; Nicola Abate; Menisha Chandalia; Chen Lab; Daping Fan; Fang Guo; Shengping Huang; Tingwan Sun; Hong-Bo Xin; Mingui Fu
Dietary obesity-induced Egr-1 in adipocytes facilitates energy storage via suppression of FOXC2.
Scientific reports 2013;3():1476.
2012: Victoria J Hammond; Emilia Kansanen; Sarah Lauder; Anna-Liisa Levonen; Clare M Lloyd; Alwena H Morgan; Sarah Brown; Andrew Bush; Chen Lab; Jane Davies; Bruce A Freeman; Yoel M Garcia-Diaz; Ned Porter; Francisco J Schopfer; Christopher P Thomas; Luis Villacorta; Valerie B O'Donnell
Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.
The Journal of biological chemistry 2012;287(50):41651-66.
2012: Yanbo Fan; Yanhong Guo; Chao-Zhong Song; Malayannan Subramaniam; Raul Urrutia; Jifeng Zhang; Chen Lab
Krüppel-like factor-11, a transcription factor involved in diabetes mellitus, suppresses endothelial cell activation via the nuclear factor-κB signaling pathway.
Arteriosclerosis, thrombosis, and vascular biology 2012;32(12):2981-8.
2012: Lin Chang; Chunyan Dou; Milton Hamblin; Rongxia Li; Luis Villacorta; Jiarui Wu; Wei Xu; Rong Zeng; Jifeng Zhang; Chen Lab
Loss of perivascular adipose tissue on peroxisome proliferator-activated receptor-γ deletion in smooth muscle cells impairs intravascular thermoregulation and enhances atherosclerosis.
Circulation 2012;126(9):1067-78.
2012: Kejie Yin; Jifeng Zhang; Milton Hamblin; Karl Olsen; Steven P Schwendeman; Chen Lab
Vascular endothelial cell-specific microRNA-15a inhibits angiogenesis in hindlimb ischemia.
The Journal of biological chemistry 2012;287(32):27055-64.
2012: Changqing Xie; Jifeng Zhang; Tianqing Zhu; Yanhong Guo; Peter X Ma; Chen Lab
Yap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.
The Journal of biological chemistry 2012;287(18):14598-605.
2012: Raghu R V Malapaka; Michael J Chalmers; Yong Xu; Jifeng Zhang; Eu-Leong Yong; James Resau; Sokkean Khoo; Patrick R Griffin; Lin Chang; Chen Lab; X Edward Zhou; Jun Li; Yinhan Gong; Jang H Choi; H Eric Xu
Identification and mechanism of 10-carbon fatty acid as modulating ligand of peroxisome proliferator-activated receptors.
The Journal of biological chemistry 2012;287(1):183-95.
2012: Lin Chang; Daniel T Eitzman; Hamblin Milton; Chen Lab
Paradoxical roles of perivascular adipose tissue in atherosclerosis and hypertension.
Circulation journal : official journal of the Japanese Circulation Society 2012;77(1):11-8.
2012: Dong Liu; Roland P Matthews; Moshood Olatinwo; Chen Lab; Minerva Garcia-Barrio; Bo Huang; Ting Kang; Yiming Lin; Wei Xu; Winston E Thompson
Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells.
PloS one 2012;7(3):e34315.
2012: Jifeng Zhang; Xiaowei Zhang; Chen Lab; Rosanne M Crooke; Mark J Graham; Ken-Ichi Hirata; Eva Hurt-Camejo; Tatsuro Ishida; Shuji Kitajima; Tomonari Koike; Enqi Liu; Kae Nakamura; Kazutoshi Nishijima; Zhongxia Qi; Masashi Shiomi; Ahmed Bilal Waqar; Jingwei Yu; Ying Yu; Jianglin Fan
Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits.
Journal of atherosclerosis and thrombosis 2012;19(3):213-26.
2011: Chen Lab; Changqing Xie; Milton Hamblin
Smooth muscle cells for vascular engineering.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(12):2772-4.
2011: Changqing Xie; Jiang Hu; Haiyun Ma; Jifeng Zhang; Lung-Ji Chang; Chen Lab; Peter X Ma
Three-dimensional growth of iPS cell-derived smooth muscle cells on nanofibrous scaffolds.
Biomaterials 2011;32(19):4369-75.
2011: Ji Zhang; Meiling Zhang; Lin Chang; Chunlei Chen; Chen Lab; Milton Hamblin; Yan Luo; Luis Villacorta; Jing-Wei Xiong; Jifeng Zhang; Xiaojun Zhu
Rad GTPase inhibits cardiac fibrosis through connective tissue growth factor.
Cardiovascular research 2011;91(1):90-8.
2011: Zhongcui Sun; Jifeng Zhang; Ji Zhang; Chunlei Chen; Quan Du; Lin Chang; Chunmei Cao; Ming Zheng; Minerva Garcia-Barrio; Chen Lab; Rui-Ping Xiao; Jieming Mao; Xiaojun Zhu
Rad GTPase induces cardiomyocyte apoptosis through the activation of p38 mitogen-activated protein kinase.
Biochemical and biophysical research communications 2011;409(1):52-7.
2011: Kejie Yin; Zhen Deng; Milton Hamblin; Jifeng Zhang; Chen Lab
Vascular PPARδ protects against stroke-induced brain injury.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(3):574-81.
2011: Milton Hamblin; Lin Chang; Hengmin Zhang; Kun Yang; Jifeng Zhang; Chen Lab
Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ mediates pioglitazone-reduced vascular lesion formation.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(2):352-9.
2011: Changqing Xie; Huarong Huang; Xuan Sun; Yanhong Guo; Milton Hamblin; Raquel P Ritchie; Minerva Garcia-Barrio; Jifeng Zhang; Chen Lab
MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4.
Stem cells and development 2011;20(2):205-10.
2010: Milton Hamblin; Lin Chang; Hengmin Zhang; Kun Yang; Jifeng Zhang; Chen Lab
Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ deletion promotes abdominal aortic aneurysms.
Journal of vascular surgery 2010;52(4):984-93.
2010: Kejie Yin; Zhen Deng; Milton Hamblin; Yi Xiang; Huarong Huang; Jifeng Zhang; Xiaodan Jiang; Yanzhuang Wang; Chen Lab
Peroxisome proliferator-activated receptor delta regulation of miR-15a in ischemia-induced cerebral vascular endothelial injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(18):6398-408.
2010: Kejie Yin; Zhen Deng; Huarong Huang; Milton Hamblin; Changqing Xie; Jifeng Zhang; Chen Lab
miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia.
Neurobiology of disease 2010;38(1):17-26.
2010: Yuqing Huo; Xin Guo; Honggui Li; Huan Wang; Weiyu Zhang; Ying Wang; Huaijun Zhou; Zhanguo Gao; Sucheta Telang; Jason Chesney; Chen Lab; Jianping Ye; Robert S Chapkin; Chaodong Wu
Disruption of inducible 6-phosphofructo-2-kinase ameliorates diet-induced adiposity but exacerbates systemic insulin resistance and adipose tissue inflammatory response.
The Journal of biological chemistry 2010;285(6):3713-21.
2009: Marsha Cole; Tanja K Rudolph; Nicholas K H Khoo; Uche N Motanya; Franca Golin-Bisello; Jeffrey W Wertz; Francisco J Schopfer; Volker Rudolph; Steven R Woodcock; Subhashini Bolisetty; Muhammad S Ali; Jifeng Zhang; Chen Lab; Anupam Agarwal; Bruce Freeman; Philip M Bauer
Nitro-fatty acid inhibition of neointima formation after endoluminal vessel injury.
Circulation research 2009;105(10):965-72.
2009: Milton Hamblin; Lin Chang; Jifeng Zhang; Chen Lab
The role of peroxisome proliferator-activated receptor gamma in blood pressure regulation.
Current hypertension reports 2009;11(4):239-45.
2009: Milton Hamblin; Lin Chang; Yanbo Fan; Jifeng Zhang; Chen Lab
PPARs and the cardiovascular system.
Antioxidants & redox signaling 2009;11(6):1415-52.
2009: Changqing Xie; Huarong Huang; Sheng Wei; Long-Sheng Song; Jifeng Zhang; Raquel P Ritchie; Liangbiao Chen; Ming Zhang; Chen Lab
A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells.
Stem cells and development 2009;18(5):741-8.
2009: Changqing Xie; Yangsik Jeong; Mingui Fu; Angie L Bookout; Minerva Garcia-Barrio; Tingwan Sun; Bong-Hyun Kim; Yang Xie; Sierra Root; Jifeng Zhang; Ren-He Xu; Chen Lab; David J Mangelsdorf
Expression profiling of nuclear receptors in human and mouse embryonic stem cells.
Molecular endocrinology (Baltimore, Md.) 2009;23(5):724-33.
2009: Lin Chang; Luis Villacorta; Jifeng Zhang; Minerva Garcia-Barrio; Kun Yang; Milton Hamblin; Steven E Whitesall; Louis G D'Alecy; Chen Lab
Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-gamma deletion leads to hypotension.
Circulation 2009;119(16):2161-9.
2009: Luis Villacorta; Francisco J Schopfer; Jifeng Zhang; Bruce Freeman; Chen Lab
PPARgamma and its ligands: therapeutic implications in cardiovascular disease.
Clinical science (London, England : 1979) 2009;116(3):205-18.
2008: Yong Li; Jifeng Zhang; Francisco J Schopfer; Dariusz Martynowski; Minerva Garcia-Barrio; Amanda Kovach; Kelly Suino-Powell; Paul Baker; Bruce Freeman; Chen Lab; H Eric Xu
Molecular recognition of nitrated fatty acids by PPAR gamma.
Nature structural & molecular biology 2008;15(8):865-7.
2008: Tomonaga Ichikawa; Jifeng Zhang; Kai Chen; Yusen Liu; Francisco J Schopfer; Paul Baker; Bruce Freeman; Chen Lab; Taixing Cui
Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: a critical role of mitogen-activated protein kinase phosphatase 1.
Endocrinology 2008;149(8):4086-94.
2007: Lin Chang; Jifeng Zhang; Yu-Hua Tseng; Changqing Xie; Jacob Ilany; Jens C Brüning; Zhongcui Sun; Xiaojun Zhu; Taixing Cui; Keith A Youker; Qinglin Yang; Sharlene M Day; C Ronald Kahn; Chen Lab
Rad GTPase deficiency leads to cardiac hypertrophy.
Circulation 2007;116(25):2976-83.
2007: Changqing Xie; Jifeng Zhang; Luis Villacorta; Taixing Cui; Huarong Huang; Chen Lab
A highly efficient method to differentiate smooth muscle cells from human embryonic stem cells.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):e311-2.
2007: Guoliang Ding; Mingui Fu; Qianhong Qin; William Lewis; Ha Won Kim; Tohru Fukai; Methode Bacanamwo; Chen Lab; Michael D Schneider; David J Mangelsdorf; Ronald M Evans; Qinglin Yang
Cardiac peroxisome proliferator-activated receptor gamma is essential in protecting cardiomyocytes from oxidative damage.
Cardiovascular research 2007;76(2):269-79.
2007: Xiaojun Zhu; Yiming Lin; Methode Bacanamwo; Lin Chang; Rui Chai; Ivana Massud; Jifeng Zhang; Minerva Garcia-Barrio; Winston E Thompson; Chen Lab
Interleukin-1 beta-induced Id2 gene expression is mediated by Egr-1 in vascular smooth muscle cells.
Cardiovascular research 2007;76(1):141-8.
2007: Luis Villacorta; Minerva Garcia-Barrio; Chen Lab
Transcriptional regulation of peroxisome proliferator-activated receptors and liver X receptors.
Current atherosclerosis reports 2007;9(3):230-7.
2007: Luis Villacorta; Jifeng Zhang; Minerva Garcia-Barrio; Xi-lin Chen; Bruce Freeman; Chen Lab; Taixing Cui
Nitro-linoleic acid inhibits vascular smooth muscle cell proliferation via the Keap1/Nrf2 signaling pathway.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H770-6.
2007: Changqing Xie; Jifeng Zhang; Yan Xiao; Li Zhang; Yongshan Mou; Xiaowei Liu; Mukaila A Akinbami; Taixing Cui; Chen Lab
Transplantation of human undifferentiated embryonic stem cells into a myocardial infarction rat model.
Stem cells and development 2007;16(1):25-9.
2006: Qingwei _ Wang; Steven C Hunt; Qin Xu; Chen Lab; Michael A Province; John H Eckfeldt; James S Pankow; QING SONG
Association study of CRP gene polymorphisms with serum CRP level and cardiovascular risk in the NHLBI Family Heart Study.
American journal of physiology. Heart and circulatory physiology 2006;291(6):H2752-7.
2006: Taixing Cui; Francisco J Schopfer; Jifeng Zhang; Kai Chen; Tomonaga Ichikawa; Paul Baker; Carlos Batthyany; Balu K Chacko; Xu Feng; Rakesh P Patel; Anupam Agarwal; Bruce Freeman; Chen Lab
Nitrated fatty acids: Endogenous anti-inflammatory signaling mediators.
The Journal of biological chemistry 2006;281(47):35686-98.
2006: Huei-Ju Pan; Yiming Lin; Chen Lab; Dennis E Vance; Edward H Leiter
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.
Vascular pharmacology 2006;45(1):65-71.
2006: Jifeng Zhang; Wei Zhong; Taixing Cui; Maozhou Yang; Xing Hu; Kefeng Xu; Changqing Xie; Changyong Xue; Gary H Gibbons; Chengyu Liu; Li Li; Chen Lab
Generation of an adult smooth muscle cell-targeted Cre recombinase mouse model.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(3):e23-4.
2005: Paul Baker; Yiming Lin; Francisco J Schopfer; Steven R Woodcock; Alison L Groeger; Carlos Batthyany; Scott Sweeney; Marshall H Long; Karen E Iles; Laura M S Baker; Bruce P Branchaud; Chen Lab; Bruce Freeman
Fatty acid transduction of nitric oxide signaling: multiple nitrated unsaturated fatty acid derivatives exist in human blood and urine and serve as endogenous peroxisome proliferator-activated receptor ligands.
The Journal of biological chemistry 2005;280(51):42464-75.
2005: Chen Xiong; Changqing Xie; Li Zhang; Jifeng Zhang; Kefeng Xu; Mingui Fu; Winston E Thompson; Li-Jun Yang; Chen Lab
Derivation of adipocytes from human embryonic stem cells.
Stem cells and development 2005;14(6):671-5.
2005: Chen Xiong; Yongshan Mou; Jifeng Zhang; Mingui Fu; Chen Lab; Mukaila A Akinbami; Taixing Cui
Impaired expression of PPAR gamma protein contributes to the exaggerated growth of vascular smooth muscle cells in spontaneously hypertensive rats.
Life sciences 2005;77(24):3037-48.
2005: Huijun Sun; Tomonari Koike; Tomonaga Ichikawa; Kinta Hatakeyama; Masashi Shiomi; Bo Zhang; Shuji Kitajima; Masatoshi Morimoto; Teruo Watanabe; Yujiro Asada; Chen Lab; Jianglin Fan
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance.
The American journal of pathology 2005;167(4):1139-48.
2005: Chen Xiong; Dong-Qi Tang; Changqing Xie; Li Zhang; Ke-Feng Xu; Winston E Thompson; Wayne Chou; Gary H Gibbons; Lung-Ji Chang; Li-Jun Yang; Chen Lab
Genetic engineering of human embryonic stem cells with lentiviral vectors.
Stem cells and development 2005;14(4):367-77.
2005: Qingwei _ Wang; Xiaojun Zhu; Qin Xu; Xia Ding; Chen Lab; QING SONG
Effect of C-reactive protein on gene expression in vascular endothelial cells.
American journal of physiology. Heart and circulatory physiology 2005;288(4):H1539-45.
2005: Mingui Fu; Jifeng Zhang; Yu-Hua Tseng; Taixing Cui; Xiaojun Zhu; Yan Xiao; Yongshan Mou; Hector De Leon; Mary M J Chang; Yasuo Hamamori; C Ronald Kahn; Chen Lab
Rad GTPase attenuates vascular lesion formation by inhibition of vascular smooth muscle cell migration.
Circulation 2005;111(8):1071-7.
2005: Francisco J Schopfer; Yiming Lin; Paul Baker; Taixing Cui; Minerva Garcia-Barrio; Jifeng Zhang; Kai Chen; Chen Lab; Bruce Freeman
Nitrolinoleic acid: an endogenous peroxisome proliferator-activated receptor gamma ligand.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(7):2340-5.
2004: Walter III Royal; Michelle V Leander; Chen Lab; Eugene O Major; Reid P Bissonnette
Nuclear receptor activation and interaction with morphine.
Journal of neuroimmunology 2004;157(1-2):61-5.
2004: Lihong Cheng; Guoliang Ding; Qianhong Qin; Yao Huang; William Lewis; Nu He; Ronald M Evans; Michael D Schneider; Florence A Brako; Yan Xiao; Chen Lab; Qinglin Yang
Cardiomyocyte-restricted peroxisome proliferator-activated receptor-delta deletion perturbs myocardial fatty acid oxidation and leads to cardiomyopathy.
Nature medicine 2004;10(11):1245-50.
2004: Chen Lab
MMP-12, an old enzyme plays a new role in the pathogenesis of rheumatoid arthritis?
The American journal of pathology 2004;165(4):1069-70.
2004: Kouichi Tamura; Chen Lab; Yutaka Tanaka; Masashi Sakai; Yuko Tsurumi; Yuichi Koide; Minoru Kihara; Richard E Pratt; Masatsugu Horiuchi; Satoshi Umemura; Victor J Dzau
Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression.
Molecular and cellular endocrinology 2004;224(1-2):11-20.
2004: Minako Yamaoka-Tojo; Masuko Fukai; Lula Hilenski; Sergey Dikalov; Chen Lab; Taiki Tojo; Tohru Fukai; Mitsuaki Fujimoto; Nikolay A Patrushev; Ningning Wang; Christopher D Kontos; George S Bloom; Wayne R Alexander
IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species--dependent endothelial migration and proliferation.
Circulation research 2004;95(3):276-83.
2004: Jifeng Zhang; Mingui Fu; Taixing Cui; Chen Xiong; Kefeng Xu; Wei Zhong; Yan Xiao; Donna Floyd; Jian Liang; En Li; QING SONG; Chen Lab
Selective disruption of PPARgamma 2 impairs the development of adipose tissue and insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(29):10703-8.
2004: Yiming Lin; Xiaojun Zhu; Farron L McLntee; Hailian Xiao; Jifeng Zhang; Mingui Fu; Chen Lab
Interferon regulatory factor-1 mediates PPARgamma-induced apoptosis in vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(2):257-63.
2004: Lihong Cheng; Guoliang Ding; Qianhong Qin; Yan Xiao; David Woods; Chen Lab; Qinglin Yang
Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes.
Biochemical and biophysical research communications 2004;313(2):277-86.
2003: Mingui Fu; Xiaojun Zhu; Jifeng Zhang; Jian Liang; Yiming Lin; Luning Zhao; Markus U Ehrengruber; Chen Lab
Egr-1 target genes in human endothelial cells identified by microarray analysis.
Gene 2003;315():33-41.
2003: Mingui Fu; Jifeng Zhang; Yiming Lin; Xiaojun Zhu; Luning Zhao; Mushtaq Ahmad; Markus U Ehrengruber; Chen Lab
Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads.
The Biochemical journal 2003;370(Pt 3):1019-25.
2003: Chen Lab; Mingui Fu; Jifeng Zhang; Xiaojun Zhu; Yiming Lin; Mukaila A Akinbami; QING SONG
Peroxisome proliferator-activated receptors and the cardiovascular system.
Vitamins and hormones 2003;66():157-88.
2003: X Zhu; Yiming Lin; Jifeng Zhang; M Fu; Z Mao; Chen Lab
Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells.
Cellular and molecular life sciences : CMLS 2003;60(1):212-8.
2002: Jifeng Zhang; Mingui Fu; Luning Zhao; Chen Lab
15-Deoxy-prostaglandin J(2) inhibits PDGF-A and -B chain expression in human vascular endothelial cells independent of PPAR gamma.
Biochemical and biophysical research communications 2002;298(1):128-32.
2002: Mingui Fu; Jifeng Zhang; Yiming Lin; Xiaojun Zhu; Markus U Ehrengruber; Chen Lab
Early growth response factor-1 is a critical transcriptional mediator of peroxisome proliferator-activated receptor-gamma 1 gene expression in human aortic smooth muscle cells.
The Journal of biological chemistry 2002;277(30):26808-14.
2002: Jifeng Zhang; Mingui Fu; David Myles; Xiaojun Zhu; Jie Du; Xu Cao; Chen Lab
PDGF induces osteoprotegerin expression in vascular smooth muscle cells by multiple signal pathways.
FEBS letters 2002;521(1-3):180-4.
2002: Mingui Fu; Jifeng Zhang; Yimin g Lin Yg; Xiaojun Zhu; Timothy M Willson; Chen Lab
Activation of peroxisome proliferator-activated receptor gamma inhibits osteoprotegerin gene expression in human aortic smooth muscle cells.
Biochemical and biophysical research communications 2002;294(3):597-601.
2002: Jifeng Zhang; Mingui Fu; Xiaojun Zhu; Yan Xiao; Yongshan Mou; Hui Zheng; Mukaila A Akinbami; Qian Wang; Chen Lab
Peroxisome proliferator-activated receptor delta is up-regulated during vascular lesion formation and promotes post-confluent cell proliferation in vascular smooth muscle cells.
The Journal of biological chemistry 2002;277(13):11505-12.
2001: Mingui Fu; Jifeng Zhang; Xiaojun Zhu; D E Myles; T M Willson; X Liu; Chen Lab
Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3.
The Journal of biological chemistry 2001;276(49):45888-94.
2001: Mingui Fu; Xiaojun Zhu; Qingwei _ Wang; Jifeng Zhang; QING SONG; H Zheng; W Ogawa; J Du; Chen Lab
Platelet-derived growth factor promotes the expression of peroxisome proliferator-activated receptor gamma in vascular smooth muscle cells by a phosphatidylinositol 3-kinase/Akt signaling pathway.
Circulation research 2001;89(11):1058-64.
2000: Kouichi Tamura; Chen Lab; Marco Lopez-Ilasaca; L Daviet; N Tamura; Tomoaki Ishigami; Masahiro Akishita; I Takasaki; Y Tokita; Richard E Pratt; Masatsugu Horiuchi; Victor J Dzau; Satoshi Umemura
Molecular mechanism of fibronectin gene activation by cyclic stretch in vascular smooth muscle cells.
The Journal of biological chemistry 2000;275(44):34619-27.
2000: Kouichi Tamura; Chen Lab; Q Chen; N Nyui; Masatsugu Horiuchi; I Takasaki; N Tamura; Richard E Pratt; Victor J Dzau; Satoshi Umemura
Expression of renin-angiotensin system and extracellular matrix genes in cardiovascular cells and its regulation through AT1 receptor.
Molecular and cellular biochemistry 2000;212(1-2):203-9.
2000: Kouichi Tamura; Chen Lab; Masatsugu Horiuchi; Q Chen; L Daviet; Z Yang; Marco Lopez-Ilasaca; Hui Mu; Richard E Pratt; Victor J Dzau
LXRalpha functions as a cAMP-responsive transcriptional regulator of gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8513-8.
2000: Masatsugu Horiuchi; W Hayashida; Masahiro Akishita; S Yamada; JY Lehtonen; Kouichi Tamura; L Daviet; Chen Lab; Meiko Hamai; Tai-Xing Cui; Masaru Iwai; Yasuhiko Minokoshi
Interferon-gamma induces AT(2) receptor expression in fibroblasts by Jak/STAT pathway and interferon regulatory factor-1.
Circulation research 2000;86(2):233-40.
1997: Chen Lab; Daniel J Drucker
Tissue-specific expression of unique mRNAs that encode proglucagon-derived peptides or exendin 4 in the lizard.
The Journal of biological chemistry 1997;272(7):4108-15.