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Roger A. Greenberg

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Chemicals & Drugs

Living Beings

Mouse

Disorders

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Publications

TOP 3
Niraj M Shanbhag; Ilona U Rafalska-Metcalf; Carlo Balane-Bolivar; Susan M Janicki; Roger A. Greenberg
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.
Szilvia Solyom; Jeffery Patterson-Fortin; Katri Pylkäs; Roger A. Greenberg; Robert Winqvist
Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families.
Timothy R Rebbeck; Nandita Mitra; Susan M Domchek; Fei Wan; Shaokun Chuai; Tara Friebel; Saarene Panossian; Amanda Spurdle; Georgia Chenevix-Trench; Christian F Singer; Georg Pfeiler; Susan L Neuhausen; Henry T Lynch; Judy E Garber; Jeffrey N Weitzel; Claudine Isaacs; Fergus J. Couch; Steven A Narod; Wendy S Rubinstein; Gail Tomlinson; Patricia Anne Ganz; Olufunmilayo I Olopade; Nadine Tung; Joanne L Blum; Roger A. Greenberg; Katherine L Nathanson; Mary B Daly
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.

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All Publications

2010: Niraj M Shanbhag; Ilona U Rafalska-Metcalf; Carlo Balane-Bolivar; Susan M Janicki; Roger A. Greenberg
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks.
Cell 2010;141(6):970-81.
2010: Szilvia Solyom; Jeffery Patterson-Fortin; Katri Pylkäs; Roger A. Greenberg; Robert Winqvist
Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families.
Breast cancer research and treatment 2010;120(1):165-8.
2009: Timothy R Rebbeck; Nandita Mitra; Susan M Domchek; Fei Wan; Shaokun Chuai; Tara Friebel; Saarene Panossian; Amanda Spurdle; Georgia Chenevix-Trench; Christian F Singer; Georg Pfeiler; Susan L Neuhausen; Henry T Lynch; Judy E Garber; Jeffrey N Weitzel; Claudine Isaacs; Fergus J. Couch; Steven A Narod; Wendy S Rubinstein; Gail Tomlinson; Patricia Anne Ganz; Olufunmilayo I Olopade; Nadine Tung; Joanne L Blum; Roger A. Greenberg; Katherine L Nathanson; Mary B Daly
Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
Cancer research 2009;69(14):5801-10.
2009: J Nikkilä; K A Coleman; D Morrissey; Katri Pylkäs; Hannele Erkko; T E Messick; Sanna-Maria Karppinen; A Amelina; Robert Winqvist; Roger A. Greenberg
Familial breast cancer screening reveals an alteration in the RAP80 UIM domain that impairs DNA damage response function.
Oncogene 2009;28(16):1843-52.
2009: Karen A Urtishak; Kevin D Smith; Rebecca A Chanoux; Roger A. Greenberg; F Brad Johnson; Eric J Brown
Timeless Maintains Genomic Stability and Suppresses Sister Chromatid Exchange during Unperturbed DNA Replication.
The Journal of biological chemistry 2009;284(13):8777-85.
2009: Genze Shao; Jeffrey Patterson-Fortin; Troy E Messick; Dan Feng; Niraj Shanbhag; Yingqun Wang; Roger A. Greenberg
MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.
Genes & development 2009;23(6):740-54.
2009: Genze Shao; Dana R Lilli; Jeffrey Patterson-Fortin; Kara A Coleman; Devon E Morrissey; Roger A. Greenberg
The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(9):3166-71.
2008: John D Gordan; Priti Lal; Vijay R Dondeti; Richard Letrero; Krishna N Parekh; C Elisa Oquendo; Roger A. Greenberg; Keith T Flaherty; Wendy Rathmell; Brian Keith; M Celeste Simon; Katherine L Nathanson
HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.
Cancer cell 2008;14(6):435-46.
2008: Roger A. Greenberg
Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network.
Chromosoma 2008;117(4):305-17.
2007: Miguel Angel Pujana; Jing-Dong J Han; Lea M Starita; Kristen N Stevens; Muneesh Tewari; Jin Sook Ahn; Gad Rennert; Víctor Moreno; Tomas Kirchhoff; Bert Gold; Volker Assmann; Wael ElShamy; Jean-François Rual; Douglas A Levine; Laura S Rozek; Rebecca Gelman; Kristin C Gunsalus; Roger A. Greenberg; Bijan Sobhian; Nicolas Bertin; Kavitha Venkatesan; Nono Ayivi-Guedehoussou; Xavier Sole; Pilar Hernández; Conxi Lázaro; Katherine L Nathanson; Barbara L Weber; Michael E Cusick; David E Hill; Kenneth Offit; David M Livingston; Stephen B Gruber; Jeffrey D Parvin; Marc Vidal
Network modeling links breast cancer susceptibility and centrosome dysfunction.
Nature genetics 2007;39(11):1338-49.
2007: Sonja Schaetzlein; N R Kodandaramireddy; Zhenyu Ju; André Lechel; Anna Stepczynska; Dana R Lilli; Alan B Clark; Cornelia Rudolph; Florian Kuhnel; Kaichun Wei; Brigitte Schlegelberger; Peter Schirmacher; Thomas A Kunkel; Roger A. Greenberg; Winfried Edelmann; K Lenhard Rudolph
Exonuclease-1 deletion impairs DNA damage signaling and prolongs lifespan of telomere-dysfunctional mice.
Cell 2007;130(5):863-77.
2007: Bijan Sobhian; Genze Shao; Dana R Lilli; Aedín C Culhane; Lisa A Moreau; Bing Xia; David M Livingston; Roger A. Greenberg
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites.
Science (New York, N.Y.) 2007;316(5828):1198-202.
2006: Roger A. Greenberg
BRCA mutations and childhood cancer.
Cancer biology & therapy 2006;5(9):1103-4.
2006: Roger A. Greenberg; Bijan Sobhian; Shailja Pathania; Sharon B Cantor; Yoshihiro Nakatani; David M Livingston
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.
Genes & development 2006;20(1):34-46.
2005: Roger A. Greenberg
Telomeres, crisis and cancer.
Current molecular medicine 2005;5(2):213-8.
2005: Roger A. Greenberg; K Lenhard Rudolph
Telomere structural dynamics in genome integrity control and carcinogenesis.
Advances in experimental medicine and biology 2005;570():311-41.
2004: Ande Satyanarayana; Roger A. Greenberg; Sonja Schaetzlein; Jan Buer; Kenkichi Masutomi; William C Hahn; S Zimmermann; U Martens; Michael P Manns; K Lenhard Rudolph
Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling.
Molecular and cellular biology 2004;24(12):5459-74.
2004: Shridar Ganesan; Daniel P Silver; Ronny Drapkin; Roger A. Greenberg; Jean Feunteun; David M Livingston
Association of BRCA1 with the inactive X chromosome and XIST RNA.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1441):123-8.
2002: Shridar Ganesan; Daniel P Silver; Roger A. Greenberg; Dror Avni; Ronny Drapkin; alexander miron; Samuel C Mok; Voahangy Randrianarison; Steven Brodie; Jennifer L Salstrom; Theodore P Rasmussen; Ann Klimke; Christine Marrese; York Marahrens; Chu-Xia Deng; Jean Feunteun; David M Livingston
BRCA1 supports XIST RNA concentration on the inactive X chromosome.
Cell 2002;111(3):393-405.
2002: Steven E Artandi; Scott Alson; Maja K Tietze; Norman E Sharpless; Siqin Ye; Roger A. Greenberg; Diego H Castrillon; James W Horner; Sarah R Weiler; Ruben D Carrasco; Ronald A DePinho
Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8191-6.
2002: Roger A. Greenberg; David B Sacks
Screening for diabetes: is it warranted?
Clinica chimica acta; international journal of clinical chemistry 2002;315(1-2):61-9.
2001: K H Lee; K Lenhard Rudolph; Y J Ju; Roger A. Greenberg; Linda Cannizzaro; Lynda Chin; Sarah R Weiler; Ronald A DePinho
Telomere dysfunction alters the chemotherapeutic profile of transformed cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3381-6.
1999: Roger A. Greenberg; Lynda Chin; Andrea M Femino; K H Lee; G J Gottlieb; Robert H Singer; Carol W Greider; Ronald A DePinho
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Cell 1999;97(4):515-25.
1999: Roger A. Greenberg; Rónán C O'Hagan; H Deng; Q Xiao; S R Hann; R R Adams; SP Lichtsteiner; Lynda Chin; Gregg B Morin; Ronald A DePinho
Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation.
Oncogene 1999;18(5):1219-26.
1998: Nicole Schreiber-Agus; Y Meng; T Hoang; Harry Hou; Ken Chen; Roger A. Greenberg; C Cordon-Cardo; H W Lee; Ronald A DePinho
Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.
Nature 1998;393(6684):483-7.
1998: Roger A. Greenberg; Rich Allsopp; Lynda Chin; Gregg B Morin; Ronald A DePinho
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation.
Oncogene 1998;16(13):1723-30.