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Gregory Brown

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Seithikurippu R Pandi-Perumal; Adam Moscovitch; Venkatramanujam Srinivasan; David Warren Spence; Daniel P Cardinali; Gregory Brown
Bidirectional communication between sleep and circadian rhythms and its implications for depression: lessons from agomelatine.
Seithikurippu R Pandi-Perumal; Venkatramanujam Srinivasan; D Warren Spence; Adam Moscovitch; Rüdiger Hardeland; Gregory Brown; Daniel P Cardinali
Ramelteon: a review of its therapeutic potential in sleep disorders.
Gregory Brown; Seithikurippu Ratnas Pandi-Perumal; Ilya Trakht; Daniel P Cardinali
Melatonin and its relevance to jet lag.

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2009: Seithikurippu R Pandi-Perumal; Adam Moscovitch; Venkatramanujam Srinivasan; David Warren Spence; Daniel P Cardinali; Gregory Brown
Bidirectional communication between sleep and circadian rhythms and its implications for depression: lessons from agomelatine.
Progress in neurobiology 2009;88(4):264-71.
2009: Seithikurippu R Pandi-Perumal; Venkatramanujam Srinivasan; D Warren Spence; Adam Moscovitch; Rüdiger Hardeland; Gregory Brown; Daniel P Cardinali
Ramelteon: a review of its therapeutic potential in sleep disorders.
Advances in therapy 2009;26(6):613-26.
2009: Gregory Brown; Seithikurippu Ratnas Pandi-Perumal; Ilya Trakht; Daniel P Cardinali
Melatonin and its relevance to jet lag.
Travel medicine and infectious disease 2009;7(2):69-81.
2007: Sana Jawed; Bora Kim; Thomas Ottenhof; Gregory Brown; Eva S Werstiuk; Lennard P Niles
Human melatonin MT1 receptor induction by valproic acid and its effects in combination with melatonin on MCF-7 breast cancer cell proliferation.
European journal of pharmacology 2007;560(1):17-22.
2004: Moisés A Rivera-Bermúdez; Monica I Masana; Gregory Brown; David J Earnest; Margarita L Dubocovich
Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors.
Brain research 2004;1002(1-2):21-7.
2003: Judite Scher; Ellen Wankiewicz; Gregory Brown; Hiroki Fujieda
AII amacrine cells express the MT1 melatonin receptor in human and macaque retina.
Experimental eye research 2003;77(3):375-82.
2003: Hiroki Fujieda; Judite Scher; W Lukita-Atmadja; Gregory Brown
Gene regulation of melatonin and dopamine receptors during eye development.
Neuroscience 2003;120(2):301-7.
2003: Jeffrey H Meyer; Shelley McMain; Sidney H Kennedy; Lorne Korman; Gregory Brown; Jean N DaSilva; Alan Wilson; Thomas Blak; Rahel Eynan-Harvey; Verdell S Goulding; Sylvain Houle; Paul S Links
Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm.
The American journal of psychiatry 2003;160(1):90-9.
2002: Celia S Pang; Si C Xi; Gregory Brown; Shiu F Pang; Stephen Y W Shiu
2[125I]Iodomelatonin binding and interaction with beta-adrenergic signaling in chick heart/coronary artery physiology.
Journal of pineal research 2002;32(4):243-52.
2002: Judite Scher; Ellen Wankiewicz; Gregory Brown; Hiroki Fujieda
MT(1) melatonin receptor in the human retina: expression and localization.
Investigative ophthalmology & visual science 2002;43(3):889-97.
2002: Robert D Levitan; Franco J Vaccarino; Gregory Brown; Sidney H Kennedy
Low-dose dexamethasone challenge in women with atypical major depression: pilot study.
Journal of psychiatry & neuroscience : JPN 2002;27(1):47-51.
2001: Deboleena Roy; N L Angelini; Hiroki Fujieda; Gregory Brown; Denise D Belsham
Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin.
Endocrinology 2001;142(11):4711-20.
2001: Cynthia H Y Fu; Laurence J Reed; Jeffrey H Meyer; S Kennedy; Sylvain Houle; Beata S Eisfeld; Gregory Brown
Noradrenergic dysfunction in the prefrontal cortex in depression: an [15O] H2O PET study of the neuromodulatory effects of clonidine.
Biological psychiatry 2001;49(4):317-25.
2001: Jeffrey H Meyer; Shitij Kapur; Beata S Eisfeld; Gregory Brown; Sylvain Houle; Jean N DaSilva; Alan Wilson; Shahryar Rafi-Tari; Helen S Mayberg; Sidney H Kennedy
The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study.
The American journal of psychiatry 2001;158(1):78-85.
2000: Si C Xi; Po-Chor Tam; Gregory Brown; Shiu F Pang; Stephen Y W Shiu
Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells.
Journal of pineal research 2000;29(3):172-83.
2000: J H Meyer; R Swinson; S H Kennedy; S Houle; Gregory Brown
Increased left posterior parietal-temporal cortex activation after D-fenfluramine in women with panic disorder.
Psychiatry research 2000;98(3):133-43.
2000: Hiroki Fujieda; Judite Scher; S A Hamadanizadeh; Ellen Wankiewicz; S F Pang; Gregory Brown
Dopaminergic and GABAergic amacrine cells are direct targets of melatonin: immunocytochemical study of mt1 melatonin receptor in guinea pig retina.
Visual neuroscience 2000;17(1):63-70.
2000: E J Dalton; D Rotondi; Robert D Levitan; Sidney H Kennedy; Gregory Brown
Use of slow-release melatonin in treatment-resistant depression.
Journal of psychiatry & neuroscience : JPN 2000;25(1):48-52.
1999: Tom M McLellan; Greg A Gannon; Jiri Zamecnik; Valerie Gil; Gregory Brown
Low doses of melatonin and diurnal effects on thermoregulation and tolerance to uncompensable heat stress.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(1):308-16.
1999: Jeffrey H Meyer; Shitij Kapur; Sylvain Houle; Jean N DaSilva; B Owczarek; Gregory Brown; Alan Wilson; Sidney H Kennedy
Prefrontal cortex 5-HT2 receptors in depression: an [18F]setoperone PET imaging study.
The American journal of psychiatry 1999;156(7):1029-34.
1999: Q Wan; Heng-Ye Man; Fang Liu; JL Braunton; Hyman B Niznik; S F Pang; Gregory Brown; Yu Tian Wang
Differential modulation of GABAA receptor function by Mel1a and Mel1b receptors.
Nature neuroscience 1999;2(5):401-3.
1999: Hiroki Fujieda; S A Hamadanizadeh; Ellen Wankiewicz; S F Pang; Gregory Brown
Expression of mt1 melatonin receptor in rat retina: evidence for multiple cell targets for melatonin.
Neuroscience 1999;93(2):793-9.
1999: George A Bubenik; Roger R Hacker; Gregory Brown; Ludek Bartos
Melatonin concentrations in the luminal fluid, mucosa, and muscularis of the bovine and porcine gastrointestinal tract.
Journal of pineal research 1999;26(1):56-63.
1999: R Lewis; Shitij Kapur; C Jones; Jean N DaSilva; Gregory Brown; Alan Wilson; Sylvain Houle; Robert B Zipursky
Serotonin 5-HT2 receptors in schizophrenia: a PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects.
The American journal of psychiatry 1999;156(1):72-8.
1998: Jeffrey H Meyer; S Kennedy; Gregory Brown
No effect of depression on [(15)O]H2O PET response to intravenous d-fenfluramine.
The American journal of psychiatry 1998;155(9):1241-6.
1998: George A Bubenik; D E Blask; Gregory Brown; G J Maestroni; SF Pang; Russel J Reiter; M Viswanathan; N Zisapel
Prospects of the clinical utilization of melatonin.
Biological signals and receptors 1998;7(4):195-219.
1998: PT Ram; Todd L Kiefer; M Silverman; Y Song; Gregory Brown; Steven M Hill
Estrogen receptor transactivation in MCF-7 breast cancer cells by melatonin and growth factors.
Molecular and cellular endocrinology 1998;141(1-2):53-64.
1998: Robert D Levitan; Allan S Kaplan; Gregory Brown; Franco J Vaccarino; Sidney H Kennedy; Anthony J Levitt; Russell T Joffe
Hormonal and subjective responses to intravenous m-chlorophenylpiperazine in women with seasonal affective disorder.
Archives of general psychiatry 1998;55(3):244-9.
1998: T M John; G Y Liu; Gregory Brown
60 Hz magnetic field exposure and urinary 6-sulphatoxymelatonin levels in the rat.
Bioelectromagnetics 1998;19(3):172-80.
1998: George A Bubenik; H L Ayles; Robert Friendship; Gregory Brown; R O Ball
Relationship between melatonin levels in plasma and gastrointestinal tissues and the incidence and severity of gastric ulcers in pigs.
Journal of pineal research 1998;24(1):62-6.
1997: Camie W Y Chan; Y Song; M Ailenberg; M Wheeler; Shiu F Pang; Gregory Brown; Mel Silverman
Studies of melatonin effects on epithelia using the human embryonic kidney-293 (HEK-293) cell line.
Endocrinology 1997;138(11):4732-9.
1997: Celia S Pang; Pak Lai Tang; Y Song; Shiu F Pang; K W Ng; B Guardiola-Lemaitre; P Delagrange; Gregory Brown
Differential inhibitory effects of melatonin analogs and three naphthalenic ligands on 2-[125I]iodomelatonin binding to chicken tissues.
Journal of pineal research 1997;23(3):148-55.
1997: Shiu F Pang; Q Wan; Gregory Brown
Melatonin receptors in the spinal cord.
Biological signals 1997;6(4-6):272-83.
1997: Robert D Levitan; Allan S Kaplan; Russell T Joffe; Anthony J Levitt; Gregory Brown
Hormonal and subjective responses to intravenous meta-chlorophenylpiperazine in bulimia nervosa.
Archives of general psychiatry 1997;54(6):521-7.
1997: Q Wan; M X Liao; Celia S Pang; Shiu F Pang; Gregory Brown
Guanosine 5'-O-(3-thiotriphosphate) and cations regulate melatonin receptors, and melatonin inhibits cyclic AMP production in the spinal cord.
Biological signals 1997;6(2):67-76.
1997: Gregory Brown
Reduced serotonin responsivity in depression.
The American journal of psychiatry 1997;154(3):442.
1997: Robert D Levitan; Allan S Kaplan; Gregory Brown; Russell T Joffe; Anthony J Levitt; Franco J Vaccarino; Sidney H Kennedy
Low plasma cortisol in bulimia nervosa patients with reversed neurovegetative symptoms of depression.
Biological psychiatry 1997;41(3):366-8.
1997: George A Bubenik; Gregory Brown
Pinealectomy reduces melatonin levels in the serum but not in the gastrointestinal tract of rats.
Biological signals 1997;6(1):40-4.
1997: Q Wan; M Liao; Gregory Brown; Shiu F Pang
The developmental and circadian variation of melatonin receptors in the chicken spinal cord.
Developmental neuroscience 1997;19(2):196-201.
1997: Y Song; Camie W Y Chan; Gregory Brown; S F Pang; Mel Silverman
Studies of the renal action of melatonin: evidence that the effects are mediated by 37 kDa receptors of the Mel1a subtype localized primarily to the basolateral membrane of the proximal tubule.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(1):93-100.
1996: S H Kennedy; S P Kutcher; E Ralevski; Gregory Brown
Nocturnal melatonin and 24-hour 6-sulphatoxymelatonin levels in various phases of bipolar affective disorder.
Psychiatry research 1996;63(2-3):219-22.
1996: Y Song; Celia S Pang; E A Ayre; Gregory Brown; Shiu F Pang
Melatonin receptors in the chicken kidney are up-regulated by pinealectomy and linked to adenylate cyclase.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(1):128-33.
1996: Jeffrey H Meyer; Shitij Kapur; Alan Wilson; Jean N DaSilva; Sylvain Houle; Gregory Brown
Neuromodulation of frontal and temporal cortex by intravenous d-fenfluramine: an [15O]H2O PET study in humans.
Neuroscience letters 1996;207(1):25-8.
1996: D S Goldbloom; Paul E Garfinkel; R Katz; Gregory Brown
The hormonal response to intravenous 5-hydroxytryptophan in bulimia nervosa.
Journal of psychosomatic research 1996;40(3):289-97.
1996: Q Wan; M Liao; Gregory Brown; Shiu F Pang
Localization and characterization of melatonin receptors in the rabbit spinal cord.
Neuroscience letters 1996;204(1-2):77-80.
1996: Michael Gemar; Shitij Kapur; Z V Segal; Gregory Brown; S Houle
Effects of self-generated sad mood on regional cerebral activity: a PET study in normal subjects.
Depression 1996;4(2):81-8.
1996: Gregory Brown; W Singer; R Joffe
Lack of association between thyroid and pineal responses to antidepressant treatment.
Depression 1996;4(2):73-6.
1996: Celia S Pang; Pak Lai Tang; Y Song; Gregory Brown; Shiu F Pang
2-[125I]Iodomelatonin binding sites in the quail heart: characteristics, distribution and modulation by guanine nucleotides and cations.
Life sciences 1996;58(13):1047-57.
1995: T M John; J C George; Gregory Brown
Effects of exogenous arginine vasotocin on circulating levels of thyroid hormones and melatonin in the pigeon, Columbia livia.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1995;112(3):345-51.
1995: Celia S Pang; Pak Lai Tang; Shiu F Pang; Gregory Brown
Comparison of the pharmacological characteristics of 2-[125I]iodomelatonin binding sites in the lung, spleen, brain and kidney of chicken.
Biological signals 1995;4(6):311-24.
1995: Fang Liu; H Yuan; Kim S Sugamori; A Hamadanizadeh; Frank J S Lee; S F Pang; Gregory Brown; Zdenek Pristupa; Hyman B Niznik
Molecular and functional characterization of a partial cDNA encoding a novel chicken brain melatonin receptor.
FEBS letters 1995;374(2):273-8.
1995: Shitij Kapur; Fergus I M Craik; C Jones; Gregory Brown; Sylvain Houle; Endel Tulving
Functional role of the prefrontal cortex in retrieval of memories: a PET study.
Neuroreport 1995;6(14):1880-4.
1995: H Yuan; Camie W Y Chan; W Q Sturner; S F Pang; Gregory Brown
Comparison of [125I]iodomelatonin binding sites in infant cerebellum of sudden infant death syndrome and non-sudden infant death syndrome.
Neuroscience letters 1995;197(2):154-8.
1995: S H Kennedy; W Gnam; E Ralevski; Gregory Brown
Melatonin responses to clonidine and yohimbine challenges.
Journal of psychiatry & neuroscience : JPN 1995;20(4):297-304.
1995: S M Yie; Gregory Brown
Effects of sex hormones on the pineal response to isoproterenol and on pineal beta-adrenergic receptors.
Neuroendocrinology 1995;62(1):93-100.
1995: Y Song; A M Poon; Gregory Brown; S F Pang
Ontogeny of 2-[125I]iodomelatonin binding sites in the chicken (Gallus domesticus) kidney and spleen.
Canadian journal of physiology and pharmacology 1995;73(6):685-92.
1995: Y Song; P C Tam; A M Poon; Gregory Brown; Shiu F Pang
2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-O-(3-thiotriphosphate).
The Journal of clinical endocrinology and metabolism 1995;80(5):1560-5.
1995: S M Yie; Gregory Brown; G Y Liu; John A Collins; Salim Daya; Edward G Hughes; Warren G Foster; Edward V Younglai
Melatonin and steroids in human pre-ovulatory follicular fluid: seasonal variations and granulosa cell steroid production.
Human reproduction (Oxford, England) 1995;10(1):50-5.
1994: Gregory Brown
Light, melatonin and the sleep-wake cycle.
Journal of psychiatry & neuroscience : JPN 1994;19(5):345-53.
1994: Shitij Kapur; R Rose; P F Liddle; R B Zipursky; Gregory Brown; Donald T Stuss; S Houle; E Tulving
The role of the left prefrontal cortex in verbal processing: semantic processing or willed action?
Neuroreport 1994;5(16):2193-6.
1994: Celia S Pang; M A Ali; P K Reddy; J F Leatherland; Gregory Brown; Shiu F Pang
2-[125I]iodomelatonin binding in the brains of four salmonids.
Biological signals 1994;3(5):230-8.
1994: E A Ayre; Z P Wang; Gregory Brown; Shiu F Pang
Localization and characterization of [125I]iodomelatonin binding sites in duck gonads.
Journal of pineal research 1994;17(1):39-47.
1994: Shitij Kapur; J Meyer; Alan Wilson; Sylvain Houle; Gregory Brown
Activation of specific cortical regions by apomorphine: an [15O]H2O PET study in humans.
Neuroscience letters 1994;176(1):21-4.
1994: Arun V Ravindran; R J Bialik; Gregory Brown; YD Lapierre
Primary early onset dysthymia, biochemical correlates of the therapeutic response to fluoxetine: II. Urinary metabolites of serotonin, norepinephrine, epinephrine and melatonin.
Journal of affective disorders 1994;31(2):119-23.
1994: Shitij Kapur; J Meyer; Alan Wilson; Sylvain Houle; Gregory Brown
Modulation of cortical neuronal activity by a serotonergic agent: a PET study in humans.
Brain research 1994;646(2):292-4.
1994: T M John; M C Brown; L Wideman; Gregory Brown
Melatonin replacement nullifies the effect of light-induced functional pinealectomy on nociceptive rhythm in the rat.
Physiology & behavior 1994;55(4):735-9.
1994: Shitij Kapur; Fergus I M Craik; Endel Tulving; A A Wilson; Sylvain Houle; Gregory Brown
Neuroanatomical correlates of encoding in episodic memory: levels of processing effect.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(6):2008-11.
1994: Kimberly M Cheng; Celia S Pang; Z P Wang; H Yuan; Cathleen R Nichols; Gregory Brown; Shiu F Pang
A comparison of [125I]iodomelatonin binding sites in testes and brains of heavy meat-type Japanese quail with a randombred strain.
The Journal of heredity 1994;85(2):136-9.
1994: Gregory Brown; Celia S Pang; Shiu F Pang
Binding sites for 2-[125I]iodomelatonin in the adrenal gland.
Biological signals 1994;3(2):91-8.
1994: Angela M S Poon; Z M Liu; Celia S Pang; Gregory Brown; Shiu F Pang
Evidence for a direct action of melatonin on the immune system.
Biological signals 1994;3(2):107-17.
1994: James E Jan; I F Abroms; Roger D Freeman; Gregory Brown; H Espezel; Mary B Connolly
Rapid cycling in severely multidisabled children: a form of bipolar affective disorder?
Pediatric neurology 1994;10(1):34-9.
1994: Celia S Pang; K F Tsang; Gregory Brown; Shiu F Pang
Specific 2-[125I]iodomelatonin binding sites in the duck adrenal gland.
Neuroscience letters 1994;165(1-2):55-8.
1993: Sidney H Kennedy; BA Davis; Gregory Brown; C G Ford; J d'Souza
Effects of chronic brofaromine administration on biogenic amines including sulphatoxymelatonin and acid metabolites in patients with bulimia nervosa.
Neurochemical research 1993;18(12):1281-5.
1993: Celia S Pang; Gregory Brown; Pak Lai Tang; Shiu F Pang
G-protein linked melatonin binding sites in the chicken lung.
Neuroscience letters 1993;162(1-2):17-20.
1993: S M Yie; E Johansson; Gregory Brown
Competitive solid-phase enzyme immunoassay for melatonin in human and rat serum and rat pineal gland.
Clinical chemistry 1993;39(11 Pt 1):2322-5.
1993: Gregory Brown; G H Stone; M P Rathbone
Primidone and rapid cycling affective disorders.
Lancet 1993;342(8876):925.
1993: Celia S Pang; Gregory Brown; Pak Lai Tang; Kimberly M Cheng; Shiu F Pang
2-[125I]iodomelatonin binding sites in the lung and heart: a link between the photoperiodic signal, melatonin, and the cardiopulmonary system.
Biological signals 1993;2(4):228-36.