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Gianluca Canettieri

Research Profile

Chemicals & Drugs

Living Beings

Mouse

Physiology

Anatomy

Disorders

Medulloblastoma

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Molecular Sequence Data

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Rocco Palermo; M E Schininà; Alessandra Vacca; Antonio F Campese; Gianluca Canettieri; Saula Checquolo; G Ferrara; Luigi Frati; Alessandra Giorgi; A Giovenco; P Grazioli; Alberto Gulino; V Kumar; Marella Maroder; M Napolitano; Isabella Screpanti
Acetylation controls Notch3 stability and function in T-cell leukemia.
Gianluca Canettieri; Laura Antonucci; Sonia Coni; Michele Della Guardia; Antonella Franchi; Alberto Gulino; Maria Giulia Santaguida; Marco Centanni
CCAAT/enhancer-binding proteins are key regulators of human type two deiodinase expression in a placenta cell line.
Alberto Gulino; Gianluca Canettieri; enrico de smaele; Lucia Di Marcotullio; Isabella Screpanti
Hedgehog/Gli control by ubiquitination/acetylation interplay.

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All Publications

2012: Rocco Palermo; M E Schininà; Alessandra Vacca; Antonio F Campese; Gianluca Canettieri; Saula Checquolo; G Ferrara; Luigi Frati; Alessandra Giorgi; A Giovenco; P Grazioli; Alberto Gulino; V Kumar; Marella Maroder; M Napolitano; Isabella Screpanti
Acetylation controls Notch3 stability and function in T-cell leukemia.
Oncogene 2012;31(33):3807-17.
2012: Gianluca Canettieri; Laura Antonucci; Sonia Coni; Michele Della Guardia; Antonella Franchi; Alberto Gulino; Maria Giulia Santaguida; Marco Centanni
CCAAT/enhancer-binding proteins are key regulators of human type two deiodinase expression in a placenta cell line.
Endocrinology 2012;153(8):4030-8.
2012: Alberto Gulino; Gianluca Canettieri; enrico de smaele; Lucia Di Marcotullio; Isabella Screpanti
Hedgehog/Gli control by ubiquitination/acetylation interplay.
Vitamins and hormones 2012;88():211-27.
2011: enrico de smaele; Lucia Di Marcotullio; Marta Moretti; Marianna Pelloni; Maria Anna Occhione; Paola Infante; Danilo Cucchi; Azzura Greco; Laura Pietrosanti; Jelena Todorovic; Sonia Coni; Gianluca Canettieri; Elisabetta Ferretti; Roberto Bei; Marella Maroder; Isabella Screpanti; Alberto Gulino
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.
Neoplasia (New York, N.Y.) 2011;13(4):374-85.
2011: Lucia Di Marcotullio; Gianluca Canettieri; Paola Infante; Azzura Greco; Alberto Gulino
Protected from the inside: endogenous histone deacetylase inhibitors and the road to cancer.
Biochimica et biophysica acta 2011;1815(2):241-52.
2011: Lucia Di Marcotullio; Anita Greco; D Mazzà; Gianluca Canettieri; L Pietrosanti; P Infante; S Coni; Milena Moretti; enrico de smaele; Elisabetta Ferretti; Isabella Screpanti; Alberto Gulino
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal.
Oncogene 2011;30(1):65-76.
2010: Agnese Po; Elisabetta Ferretti; Evelina Miele; enrico de smaele; Arianna Paganelli; Gianluca Canettieri; Sonia Coni; Lucia Di Marcotullio; Mauro Biffoni; Luca Massimi; Concezio Di Rocco; Isabella Screpanti; Alberto Gulino
Hedgehog controls neural stem cells through p53-independent regulation of Nanog.
The EMBO journal 2010;29(15):2646-58.
2010: Gianluca Canettieri; Lucia Di Marcotullio; Sonia Coni; Azzura Greco; Alberto Gulino
Turning off the switch in medulloblastoma: the inhibitory acetylation of an oncogene.
Cell cycle (Georgetown, Tex.) 2010;9(11):2047-8.
2010: Gianluca Canettieri; Lucia Di Marcotullio; Azzura Greco; Sonia Coni; Laura Antonucci; Paola Infante; Laura Pietrosanti; enrico de smaele; Elisabetta Ferretti; Evelina Miele; Marianna Pelloni; Giuseppina De Simone; Emilia Maria Pedone; paola gallinari; Alessandra Giorgi; Christian Steinkühler; Luigi Vitagliano; Carlo Pedone; M Eugenià Schinin; Isabella Screpanti; Alberto Gulino
Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation.
Nature cell biology 2010;12(2):132-42.
2009: Gianluca Canettieri; Sonia Coni; Laura Antonucci; Laura Di Magno; Alberto Gulino
TORCs/CRTCs: more than mere coincidence.
Cell cycle (Georgetown, Tex.) 2009;8(7):963-4.
2009: Gianluca Canettieri; Sonia Coni; Michele Della Guardia; Valentina Nocerino; Laura Antonucci; Laura Di Magno; Robert Screaton; Isabella Screpanti; Giuseppe Giannini; Alberto Gulino
The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(5):1445-50.
2008: Gianluca Canettieri; Antonella Franchi; Michele Della Guardia; Ianessa Morantte; Maria Giulia Santaguida; John W Harney; P Reed Larsen; Marco Centanni
Activation of thyroid hormone is transcriptionally regulated by epidermal growth factor in human placenta-derived JEG3 cells.
Endocrinology 2008;149(2):695-702.
2008: enrico de smaele; Caterina Fragomeli; Elisabetta Ferretti; Marianna Pelloni; Agnese Po; Gianluca Canettieri; Sonia Coni; Lucia Di Marcotullio; Azzura Greco; Marta Moretti; Concezio Di Rocco; Simonetta Pazzaglia; Marella Maroder; Isabella Screpanti; Giuseppe Giannini; Alberto Gulino
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma.
Neoplasia (New York, N.Y.) 2008;10(1):89-98.
2006: Marco Centanni; Lucilla Gargano; Gianluca Canettieri; Nicola Viceconti; Antonella Franchi; Gianfranco Delle Fave; Bruno Annibale
Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis.
The New England journal of medicine 2006;354(17):1787-95.
2005: Gianluca Canettieri; Seung-Hoi Koo; Rebecca Berdeaux; Jose Heredia; Susan Hedrick; Xinmin Zhang; Marc Montminy
Dual role of the coactivator TORC2 in modulating hepatic glucose output and insulin signaling.
Cell metabolism 2005;2(5):331-8.
2005: Xinmin Zhang; Duncan T Odom; Seung-Hoi Koo; Michael D Conkright; Gianluca Canettieri; Jennifer Best; Huaming Chen; Richard G Jenner; Elizabeth Herbolsheimer; Elizabeth Jacobsen; Shilpa Kadam; SD MA; Beverly M Emerson; John B Hogenesch; Terry G Unterman; Richard A Young; Marc Montminy
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4459-64.
2004: Robert A Screaton; Michael D Conkright; Yoshiko Katoh; Jennifer L Best; Gianluca Canettieri; Shawn Jeffries; Ernesto Guzman; Sherry Niessen; John R Yates; Hiroshi Takemori; Mitsuhiro Okamoto; Marc Montminy
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
Cell 2004;119(1):61-74.
2004: Gianluca Canettieri; Antonella Franchi; Rosanna Sibilla; Ernesto Guzmán; Marco Centanni
Functional characterisation of the CRE/TATA box unit of type 2 deiodinase gene promoter in a human choriocarcinoma cell line.
Journal of molecular endocrinology 2004;33(1):51-8.
2003: Michael D Conkright; Gianluca Canettieri; Robert A Screaton; Ernesto Guzman; Loren Miraglia; John B Hogenesch; Marc Montminy
TORCs: transducers of regulated CREB activity.
Molecular cell 2003;12(2):413-23.
2003: Nicola Viceconti; S Luisi; S Nardo; Lucilla Gargano; Antonella Franchi; Rosanna Sibilla; Gianluca Canettieri; Felice Petraglia; Marco Centanni
Increased serum inhibin B levels in postmenopausal women with altered thyroid function.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2003;35(8):498-501.
2003: Ulupi S Jhala; Gianluca Canettieri; Robert A Screaton; Rohit N Kulkarni; Stan Krajewski; John Reed; John Walker; Xueying Lin; Morris White; Marc Montminy
cAMP promotes pancreatic beta-cell survival via CREB-mediated induction of IRS2.
Genes & development 2003;17(13):1575-80.
2003: Gianluca Canettieri; Ianessa Morantte; Ernesto Guzmán; Hiroshi Asahara; Stephan Herzig; Scott D Anderson; John R Yates; Marc Montminy
Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex.
Nature structural biology 2003;10(3):175-81.
2002: Marco Centanni; Nicola Viceconti; S Luisi; F M Reis; Lucilla Gargano; F Maiani; Antonella Franchi; Gianluca Canettieri; Felice Petraglia
Reversible increase of serum activin A levels in women with Graves' disease.
Journal of endocrinological investigation 2002;25(11):967-70.
2001: Benhard Mayr; Gianluca Canettieri; Marc Montminy
Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10936-41.
2000: Francesco S Celi; Gianluca Canettieri; Daniela Mentuccia; Laura Proietti-Pannunzi; Angela Fumarola; Rosanna Sibilla; V Predazzi; Marina Ferraro; Mario Andreoli; Marco Centanni
Structural organization and chromosomal localization of the human type II deiodinase gene.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(2):267-71.
2000: Marco Centanni; Gianluca Canettieri; Nicola Viceconti; Rosanna Sibilla; A Bei; Mario Andreoli
Effect of tryptophan on the early tri-iodothyronine uptake in mouse thymocytes.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(1):119-23.
2000: Gianluca Canettieri; Francesco S Celi; G Baccheschi; Luisa Salvatori; Mario Andreoli; Marco Centanni
Isolation of human type 2 deiodinase gene promoter and characterization of a functional cyclic adenosine monophosphate response element.
Endocrinology 2000;141(5):1804-13.
1998: Francesco S Celi; Gianluca Canettieri; David P Yarnall; D K Burns; Mario Andreoli; Alan R Shuldiner; Marco Centanni
Genomic characterization of the coding region of the human type II 5'-deiodinase gene.
Molecular and cellular endocrinology 1998;141(1-2):49-52.
1998: Marco Centanni; Giuseppe Maiani; Francesco Vermiglio; Gianluca Canettieri; A L Sanna; Fabiola Moretti; Francesco Trimarchi; Mario Andreoli
Combined impairment of nutritional parameters and thyroid homeostasis in mildly iodine-deficient children.
Thyroid : official journal of the American Thyroid Association 1998;8(2):155-9.
1997: Marco Centanni; Roberto Cesareo; O Verallo; M Brinelli; Gianluca Canettieri; Nicola Viceconti; Mario Andreoli
Reversible increase of intraocular pressure in subclinical hypothyroid patients.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(6):595-8.
1996: Claudio Letizia; Marco Centanni; Luigi Scuro; Gianluca Canettieri; Sabrina Cerci; A De Ciocchis; C D'Ambrosio; D Scavo
High plasma levels of endothelin-1 in untreated Addison's disease.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(6):696-9.