Richard novick

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Ubeda Carles; Olivarez Nicholas P; Barry Peter; Wang Huaibin; Kong Xiangpeng; Matthews Avery; Tallent Sandra M; Christie Gail E; Novick Richard P
Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.
Geisinger Edward; Muir Tom W; Novick Richard P
agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides.
Selva Laura; Viana David; Regev-Yochay Gili; Trzcinski Krzysztof; Corpa Juan Manuel; Lasa Iñigo; Novick Richard P; Penadés José R
Killing niche competitors by remote-control bacteriophage induction.

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All Publications

2009: Ubeda Carles; Olivarez Nicholas P; Barry Peter; Wang Huaibin; Kong Xiangpeng; Matthews Avery; Tallent Sandra M; Christie Gail E; Novick Richard P
Specificity of staphylococcal phage and SaPI DNA packaging as revealed by integrase and terminase mutations.
Molecular microbiology 2009;72(1):98-108.
2009: Geisinger Edward; Muir Tom W; Novick Richard P
agr receptor mutants reveal distinct modes of inhibition by staphylococcal autoinducing peptides.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1216-21.
2009: Selva Laura; Viana David; Regev-Yochay Gili; Trzcinski Krzysztof; Corpa Juan Manuel; Lasa Iñigo; Novick Richard P; Penadés José R
Killing niche competitors by remote-control bacteriophage induction.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1234-8.
2009: Chen John; Novick Richard P
Phage-mediated intergeneric transfer of toxin genes.
Science (New York, N.Y.) 2009;323(5910):139-41.
2008: Shopsin Bo; Drlica-Wagner Alex; Mathema Barun; Adhikari Rajan P; Kreiswirth Barry N; Novick Richard P
Prevalence of agr dysfunction among colonizing Staphylococcus aureus strains.
The Journal of infectious diseases 2008;198(8):1171-4.
2008: Traber Katrina E; Lee Elsie; Benson Sarah; Corrigan Rebecca; Cantera Mariela; Shopsin Bo; Novick Richard P
agr function in clinical Staphylococcus aureus isolates.
Microbiology (Reading, England) 2008;154(Pt 8):2265-74.
2008: George Elizabeth A; Novick Richard P; Muir Tom W
Cyclic peptide inhibitors of staphylococcal virulence prepared by Fmoc-based thiolactone peptide synthesis.
Journal of the American Chemical Society 2008;130(14):4914-24.
2008: Tormo María Angeles; Ferrer María Desamparados; Maiques Elisa; Ubeda Carles; Selva Laura; Lasa Iñigo; Calvete Juan J; Novick Richard P; Penadés José R
Staphylococcus aureus pathogenicity island DNA is packaged in particles composed of phage proteins.
Journal of bacteriology 2008;190(7):2434-40.
2008: Geisinger Edward; George Elizabeth A; Muir Tom W; Novick Richard P
Identification of ligand specificity determinants in AgrC, the Staphylococcus aureus quorum-sensing receptor.
The Journal of biological chemistry 2008;283(14):8930-8.
2008: Adhikari Rajan P; Novick Richard P
Regulatory organization of the staphylococcal sae locus.
Microbiology (Reading, England) 2008;154(Pt 3):949-59.
2008: Novick Richard P
Medicine. Combating impervious bugs.
Science (New York, N.Y.) 2008;319(5865):910-1.
2008: Ubeda Carles; Maiques Elisa; Barry Peter; Matthews Avery; Tormo María Angeles; Lasa Iñigo; Novick Richard P; Penadés José R
SaPI mutations affecting replication and transfer and enabling autonomous replication in the absence of helper phage.
Molecular microbiology 2008;67(3):493-503.
2008: Novick Richard P; Geisinger Edward
Quorum sensing in staphylococci.
Annual review of genetics 2008;42():541-64.
2007: Subedi Abhignya; Ubeda Carles; Adhikari Rajan P; Penadés José R; Novick Richard P
Sequence analysis reveals genetic exchanges and intraspecific spread of SaPI2, a pathogenicity island involved in menstrual toxic shock.
Microbiology (Reading, England) 2007;153(Pt 10):3235-45.
2007: Ubeda Carles; Barry Peter; Penadés José R; Novick Richard P
A pathogenicity island replicon in Staphylococcus aureus replicates as an unstable plasmid.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14182-8.
2007: Adhikari Rajan P; Arvidson Staffan; Novick Richard P
A nonsense mutation in agrA accounts for the defect in agr expression and the avirulence of Staphylococcus aureus 8325-4 traP::kan.
Infection and immunity 2007;75(9):4534-40.
2007: Maiques Elisa; Ubeda Carles; Tormo María Angeles; Ferrer María Desamparados; Lasa Iñigo; Novick Richard P; Penadés José R
Role of staphylococcal phage and SaPI integrase in intra- and interspecies SaPI transfer.
Journal of bacteriology 2007;189(15):5608-16.
2007: Ubeda Carles; Maiques Elisa; Tormo Maria Angeles; Campoy Susana; Lasa Iñigo; Barbé Jordi; Novick Richard P; Penadés José R
SaPI operon I is required for SaPI packaging and is controlled by LexA.
Molecular microbiology 2007;65(1):41-50.
2007: Chen John; Novick Richard P
svrA, a multi-drug exporter, does not control agr.
Microbiology (Reading, England) 2007;153(Pt 5):1604-8.
2007: Novick Richard P; Subedi Abhignya
The SaPIs: mobile pathogenicity islands of Staphylococcus.
Chemical immunology and allergy 2007;93():42-57.
2006: Geisinger Edward; Adhikari Rajan P; Jin Ruzhong; Ross Hope F; Novick Richard P
Inhibition of rot translation by RNAIII, a key feature of agr function.
Molecular microbiology 2006;61(4):1038-48.
2006: Yao Jun; Zhong Jin; Fang Yuan; Geisinger Edward; Novick Richard P; Lambowitz Alan M
Use of targetrons to disrupt essential and nonessential genes in Staphylococcus aureus reveals temperature sensitivity of Ll.LtrB group II intron splicing.
RNA (New York, N.Y.) 2006;12(7):1271-81.
2006: Maiques Elisa; Ubeda Carles; Campoy Susana; Salvador Noelia; Lasa Iñigo; Novick Richard P; Barbé Jordi; Penadés José R
beta-lactam antibiotics induce the SOS response and horizontal transfer of virulence factors in Staphylococcus aureus.
Journal of bacteriology 2006;188(7):2726-9.
2005: Novick Richard P
Interrupters on the bacterial party line.
Nature chemical biology 2005;1(6):321-2.
2005: Adhikari Rajan P; Novick Richard P
Subinhibitory cerulenin inhibits staphylococcal exoprotein production by blocking transcription rather than by blocking secretion.
Microbiology (Reading, England) 2005;151(Pt 9):3059-69.
2005: Wright Jesse S; Traber Katrina E; Corrigan Rebecca; Benson Sarah A; Musser James M; Novick Richard P
The agr radiation: an early event in the evolution of staphylococci.
Journal of bacteriology 2005;187(16):5585-94.
2005: Sakoulas George; Eliopoulos George M; Fowler Vance G; Moellering Robert C; Novick Richard P; Lucindo Natalie; Yeaman Michael R; Bayer Arnold S
Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function.
Antimicrobial agents and chemotherapy 2005;49(7):2687-92.
2005: Ji Guangyong; Pei Wuhong; Zhang Linsheng; Qiu Rongde; Lin Jianqun; Benito Yvonne; Lina Gerard; Novick Richard P
Staphylococcus intermedius produces a functional agr autoinducing peptide containing a cyclic lactone.
Journal of bacteriology 2005;187(9):3139-50.
2005: Ubeda Carles; Maiques Elisa; Knecht Erwin; Lasa Iñigo; Novick Richard P; Penadés José R
Antibiotic-induced SOS response promotes horizontal dissemination of pathogenicity island-encoded virulence factors in staphylococci.
Molecular microbiology 2005;56(3):836-44.
2005: Wright Jesse S; Jin Rhuzong; Novick Richard P
Transient interference with staphylococcal quorum sensing blocks abscess formation.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1691-6.
2004: Weinrick Brian; Dunman Paul M; McAleese Fionnuala; Murphy Ellen; Projan Steven J; Fang Yuan; Novick Richard P
Effect of mild acid on gene expression in Staphylococcus aureus.
Journal of bacteriology 2004;186(24):8407-23.
2004: Wright Jesse S; Lyon Gholson J; George Elizabeth A; Muir Tom W; Novick Richard P
Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(46):16168-73.
2004: Charpentier Emmanuelle; Anton Ana I; Barry Peter; Alfonso Berenice; Fang Yuan; Novick Richard P
Novel cassette-based shuttle vector system for gram-positive bacteria.
Applied and environmental microbiology 2004;70(10):6076-85.
2004: Mangold Monika; Siller Maria; Roppenser Bernhard; Vlaminckx Bart J M; Penfound Tom A; Klein Reinhard; Novak Rodger; Novick Richard P; Charpentier Emmanuelle
Synthesis of group A streptococcal virulence factors is controlled by a regulatory RNA molecule.
Molecular microbiology 2004;53(5):1515-27.
2004: Lyon Gholson J; Novick Richard P
Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria.
Peptides 2004;25(9):1389-403.
2004: Wirth Thierry; Wang Xiaoyan; Linz Bodo; Novick Richard P; Lum J Koji; Blaser Martin; Morelli Giovanna; Falush Daniel; Achtman Mark
Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: lessons from Ladakh.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4746-51.
2004: Tseng Jen-Chieh; Levin Brandi; Hurtado Alicia; Yee Herman; Perez de Castro Ignacio; Jimenez Maria; Shamamian Peter; Jin Ruzhong; Novick Richard P; Pellicer Angel; Meruelo Daniel
Systemic tumor targeting and killing by Sindbis viral vectors.
Nature biotechnology 2004;22(1):70-7.
2003: Novick Richard P; Jiang Dunrong
The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing.
Microbiology (Reading, England) 2003;149(Pt 10):2709-17.
2003: Novick Richard P
Autoinduction and signal transduction in the regulation of staphylococcal virulence.
Molecular microbiology 2003;48(6):1429-49.
2003: Novick Richard P
Mobile genetic elements and bacterial toxinoses: the superantigen-encoding pathogenicity islands of Staphylococcus aureus.
Plasmid 2003;49(2):93-105.
2003: Sakoulas George; Eliopoulos George M; Moellering Robert C; Novick Richard P; Venkataraman Lata; Wennersten Christine; DeGirolami Paola C; Schwaber Mitchell J; Gold Howard S
Staphylococcus aureus accessory gene regulator (agr) group II: is there a relationship to the development of intermediate-level glycopeptide resistance?
The Journal of infectious diseases 2003;187(6):929-38.
2002: Romero-Gallo Judith; Pérez-Pérez Guillermo I; Novick Richard P; Kamath Patrick; Norbu Tsering; Blaser Martin J
Responses of endoscopy patients in Ladakh, India, to Helicobacter pylori whole-cell and Cag A antigens.
Clinical and diagnostic laboratory immunology 2002;9(6):1313-7.
2002: Zhang Linsheng; Gray Lillian; Novick Richard P; Ji Guangyong
Transmembrane topology of AgrB, the protein involved in the post-translational modification of AgrD in Staphylococcus aureus.
The Journal of biological chemistry 2002;277(38):34736-42.
2002: Lyon Gholson J; Wright Jesse S; Muir Tom W; Novick Richard P
Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus.
Biochemistry 2002;41(31):10095-104.
2002: Vojtov Nikola; Ross Hope F; Novick Richard P
Global repression of exotoxin synthesis by staphylococcal superantigens.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10102-7.
2002: Sakoulas George; Eliopoulos George M; Moellering Robert C; Wennersten Christine; Venkataraman Lata; Novick Richard P; Gold Howard S
Accessory gene regulator (agr) locus in geographically diverse Staphylococcus aureus isolates with reduced susceptibility to vancomycin.
Antimicrobial agents and chemotherapy 2002;46(5):1492-502.
2002: Dufour Philippe; Jarraud Sophie; Vandenesch Francois; Greenland Timothy; Novick Richard P; Bes Michele; Etienne Jerome; Lina Gerard
High genetic variability of the agr locus in Staphylococcus species.
Journal of bacteriology 2002;184(4):1180-6.
2002: Lyon Gholson J; Wright Jesse S; Christopoulos Arthur; Novick Richard P; Muir Tom W
Reversible and specific extracellular antagonism of receptor-histidine kinase signaling.
The Journal of biological chemistry 2002;277(8):6247-53.
2001: Jin R; Novick R P
Role of the double-strand origin cruciform in pT181 replication.
Plasmid 2001;46(2):95-105.
2001: Ruzin A; Lindsay J; Novick R P
Molecular genetics of SaPI1--a mobile pathogenicity island in Staphylococcus aureus.
Molecular microbiology 2001;41(2):365-77.
2001: Novick R P; Schlievert P; Ruzin A
Pathogenicity and resistance islands of staphylococci.
Microbes and infection / Institut Pasteur 2001;3(7):585-94.
2001: Herbert S; Barry P; Novick R P
Subinhibitory clindamycin differentially inhibits transcription of exoprotein genes in Staphylococcus aureus.
Infection and immunity 2001;69(5):2996-3003.
2001: Orwin P M; Leung D Y; Donahue H L; Novick R P; Schlievert P M
Biochemical and biological properties of Staphylococcal enterotoxin K.
Infection and immunity 2001;69(1):360-6.
2000: Lyon G J; Mayville P; Muir T W; Novick R P
Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13330-5.
2000: Jarraud S; Lyon G J; Figueiredo A M; Gérard L; Vandenesch F; Etienne J; Muir T W; Novick R P
Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus.
Journal of bacteriology 2000;182(22):6517-22.
2000: Ruzin A; Novick R P
Equivalence of lauric acid and glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus.
Journal of bacteriology 2000;182(9):2668-71.
2000: Novick R P
Sortase: the surface protein anchoring transpeptidase and the LPXTG motif.
Trends in microbiology 2000;8(4):148-51.
1999: Novick R P; Muir T W
Virulence gene regulation by peptides in staphylococci and other Gram-positive bacteria.
Current opinion in microbiology 1999;2(1):40-5.
1999: Mayville P; Ji G; Beavis R; Yang H; Goger M; Novick R P; Muir T W
Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1218-23.
1998: Novick R P
Contrasting lifestyles of rolling-circle phages and plasmids.
Trends in biochemical sciences 1998;23(11):434-8.
1998: Lindsay J A; Ruzin A; Ross H F; Kurepina N; Novick R P
The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus.
Molecular microbiology 1998;29(2):527-43.
1998: Lina G; Jarraud S; Ji G; Greenland T; Pedraza A; Etienne J; Novick R P; Vandenesch F
Transmembrane topology and histidine protein kinase activity of AgrC, the agr signal receptor in Staphylococcus aureus.
Molecular microbiology 1998;28(3):655-62.
1998: Ruzin A; Novick R P
Glycerol monolaurate inhibits induction of vancomycin resistance in Enterococcus faecalis.
Journal of bacteriology 1998;180(1):182-5.
1997: Jin R; Fernandez-Beros M E; Novick R P
Why is the initiation nick site of an AT-rich rolling circle plasmid at the tip of a GC-rich cruciform?
The EMBO journal 1997;16(14):4456-66.
1997: Ji G; Beavis R; Novick R P
Bacterial interference caused by autoinducing peptide variants.
Science (New York, N.Y.) 1997;276(5321):2027-30.
1997: Jin R; Rasooly A; Novick R P
In vitro inhibitory activity of RepC/C*, the inactivated form of the pT181 plasmid initiation protein, RepC.
Journal of bacteriology 1997;179(1):141-7.
1996: Jin R; Zhou X; Novick R P
The inactive pT181 initiator heterodimer, RepC/C, binds but fails to induce melting of the plasmid replication origin.
The Journal of biological chemistry 1996;271(49):31086-91.
1996: Witcher K J; Novick R P; Schlievert P M
Modulation of immune cell proliferation by glycerol monolaurate.
Clinical and diagnostic laboratory immunology 1996;3(1):10-3.
1996: Murray D L; Earhart C A; Mitchell D T; Ohlendorf D H; Novick R P; Schlievert P M
Localization of biologically important regions on toxic shock syndrome toxin 1.
Infection and immunity 1996;64(1):371-4.
1995: Ji G; Beavis R C; Novick R P
Cell density control of staphylococcal virulence mediated by an octapeptide pheromone.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(26):12055-9.
1995: Balaban N; Novick R P
Translation of RNAIII, the Staphylococcus aureus agr regulatory RNA molecule, can be activated by a 3'-end deletion.
FEMS microbiology letters 1995;133(1-2):155-61.
1995: Nesin M; Projan S J; Kreiswirth B; Bolt Y; Novick R P
Molecular epidemiology of Staphylococcus epidermidis blood isolates from neonatal intensive care unit patients.
The Journal of hospital infection 1995;31(2):111-21.
1995: Novick R P; Projan S J; Kornblum J; Ross H F; Ji G; Kreiswirth B; Vandenesch F; Moghazeh S
The agr P2 operon: an autocatalytic sensory transduction system in Staphylococcus aureus.
Molecular & general genetics : MGG 1995;248(4):446-58.
1995: Balaban N; Novick R P
Autocrine regulation of toxin synthesis by Staphylococcus aureus.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1619-23.
1994: Rasooly A; Wang P Z; Novick R P
Replication-specific conversion of the Staphylococcus aureus pT181 initiator protein from an active homodimer to an inactive heterodimer.
The EMBO journal 1994;13(21):5245-51.
1994: Lebeau C; Vandenesch F; Greenland T; Novick R P; Etienne J
Coagulase expression in Staphylococcus aureus is positively and negatively modulated by an agr-dependent mechanism.
Journal of bacteriology 1994;176(17):5534-6.
1994: Projan S J; Brown-Skrobot S; Schlievert P M; Vandenesch F; Novick R P
Glycerol monolaurate inhibits the production of beta-lactamase, toxic shock toxin-1, and other staphylococcal exoproteins by interfering with signal transduction.
Journal of bacteriology 1994;176(14):4204-9.
1994: Vandenesch F; Lebeau C; Bes M; McDevitt D; Greenland T; Novick R P; Etienne J
Coagulase deficiency in clinical isolates of Staphylococcus aureus involves both transcriptional and post-transcriptional defects.
Journal of medical microbiology 1994;40(5):344-9.
1994: Rasooly A; Projan S J; Novick R P
Plasmids of the pT181 family show replication-specific initiator protein modification.
Journal of bacteriology 1994;176(8):2450-3.
1994: Murray D L; Prasad G S; Earhart C A; Leonard B A; Kreiswirth B N; Novick R P; Ohlendorf D H; Schlievert P M
Immunobiologic and biochemical properties of mutants of toxic shock syndrome toxin-1.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):87-95.
1993: Prasad G S; Earhart C A; Murray D L; Novick R P; Schlievert P M; Ohlendorf D H
Structure of toxic shock syndrome toxin 1.
Biochemistry 1993;32(50):13761-6.
1993: Earhart C A; Prasad G S; Murray D L; Novick R P; Schlievert P M; Ohlendorf D H
Growth and analysis of crystal forms of toxic shock syndrome toxin 1.
Proteins 1993;17(3):329-34.
1993: Rasooly A; Novick R P
Replication-specific inactivation of the pT181 plasmid initiator protein.
Science (New York, N.Y.) 1993;262(5136):1048-50.
1993: Novick R P; Ross H F; Projan S J; Kornblum J; Kreiswirth B; Moghazeh S
Synthesis of staphylococcal virulence factors is controlled by a regulatory RNA molecule.
The EMBO journal 1993;12(10):3967-75.
1993: Bargonetti J; Wang P Z; Novick R P
Measurement of gene expression by translational coupling: effect of copy mutations on pT181 initiator synthesis.
The EMBO journal 1993;12(9):3659-67.
1993: Vandenesch F; Projan S J; Kreiswirth B; Etienne J; Novick R P
Agr-related sequences in Staphylococcus lugdunensis.
FEMS microbiology letters 1993;111(1):115-22.
1993: Wang P Z; Projan S J; Henriquez V; Novick R P
Origin recognition specificity in pT181 plasmids is determined by a functionally asymmetric palindromic DNA element.
The EMBO journal 1993;12(1):45-52.
1993: Kreiswirth B; Kornblum J; Arbeit R D; Eisner W; Maslow J N; McGeer A; Low D E; Novick R P
Evidence for a clonal origin of methicillin resistance in Staphylococcus aureus.
Science (New York, N.Y.) 1993;259(5092):227-30.
1992: Regassa L B; Novick R P; Betley M J
Glucose and nonmaintained pH decrease expression of the accessory gene regulator (agr) in Staphylococcus aureus.
Infection and immunity 1992;60(8):3381-8.
1992: Lee P K; Kreiswirth B N; Deringer J R; Projan S J; Eisner W; Smith B L; Carlson E; Novick R P; Schlievert P M
Nucleotide sequences and biologic properties of toxic shock syndrome toxin 1 from ovine- and bovine-associated Staphylococcus aureus.
The Journal of infectious diseases 1992;165(6):1056-63.
1992: Schlievert P M; Deringer J R; Kim M H; Projan S J; Novick R P
Effect of glycerol monolaurate on bacterial growth and toxin production.
Antimicrobial agents and chemotherapy 1992;36(3):626-31.
1992: Projan S J; Novick R P
cis-inhibitory elements in the pT181 replication system.
Plasmid 1992;27(2):81-92.
1992: Wang P Z; Projan S J; Henriquez V; Novick R P
Specificity of origin recognition by replication initiator protein in plasmids of the pT181 family is determined by a six amino acid residue element.
Journal of molecular biology 1992;223(1):145-58.
1991: Vandenesch F; Kornblum J; Novick R P
A temporal signal, independent of agr, is required for hla but not spa transcription in Staphylococcus aureus.
Journal of bacteriology 1991;173(20):6313-20.
1991: Wang P Z; Projan S J; Novick R P
Nucleotide sequence of beta-lactamase regulatory genes from staphylococcal plasmid pI258.
Nucleic acids research 1991;19(14):4000.
1991: Wang P Z; Henriquez V B; Projan S J; Iordanescu S; Novick R P
The effect of plasmid copy number mutations on pT181 replication initiator protein expression.
Plasmid 1991;25(3):198-207.
1991: Lee P K; Deringer J R; Kreiswirth B N; Novick R P; Schlievert P M
Fluid replacement protection of rabbits challenged subcutaneous with toxic shock syndrome toxins.
Infection and immunity 1991;59(3):879-84.
1991: Novick R P
In memoriam. Royston C. Clowes (1921-1989).
Plasmid 1991;25(1):1-2.
1991: Novick R P
Genetic systems in staphylococci.
Methods in enzymology 1991;204():587-636.
1990: Noirot P; Bargonetti J; Novick R P
Initiation of rolling-circle replication in pT181 plasmid: initiator protein enhances cruciform extrusion at the origin.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8560-4.
1990: McCollister B D; Kreiswirth B N; Novick R P; Schlievert P M
Production of toxic shock syndrome-like illness in rabbits by Staphylococcus aureus D4508: association with enterotoxin A.
Infection and immunity 1990;58(7):2067-70.
1990: Norton S D; Schlievert P M; Novick R P; Jenkins M K
Molecular requirements for T cell activation by the staphylococcal toxic shock syndrome toxin-1.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(6):2089-95.
1990: Highlander S K; Novick R P
Mutational and physiological analyses of plasmid pT181 functions expressing incompatibility.
Plasmid 1990;23(1):1-15.
1989: Novick R P; Iordanescu S; Projan S J; Kornblum J; Edelman I
pT181 plasmid replication is regulated by a countertranscript-driven transcriptional attenuator.
Cell 1989;59(2):395-404.
1989: Projan S J; Kornblum J; Kreiswirth B; Moghazeh S L; Eisner W; Novick R P
Nucleotide sequence: the beta-hemolysin gene of Staphylococcus aureus.
Nucleic acids research 1989;17(8):3305.
1989: Gennaro M L; Iordanescu S; Novick R P; Murray R W; Steck T R; Khan S A
Functional organization of the plasmid pT181 replication origin.
Journal of molecular biology 1989;205(2):355-62.
1989: Kreiswirth B N; Projan S J; Schlievert P M; Novick R P
Toxic shock syndrome toxin 1 is encoded by a variable genetic element.
Reviews of infectious diseases 1989;11 Suppl 1():S83-8; discussion S88-9.
1989: Novick R P
Staphylococcal plasmids and their replication.
Annual review of microbiology 1989;43():537-65.
1988: Gennaro M L; Novick R P
An enhancer of DNA replication.
Journal of bacteriology 1988;170(12):5709-17.
1988: Chu M C; Kreiswirth B N; Pattee P A; Novick R P; Melish M E; James J F
Association of toxic shock toxin-1 determinant with a heterologous insertion at multiple loci in the Staphylococcus aureus chromosome.
Infection and immunity 1988;56(10):2702-8.
1988: Peng H L; Novick R P; Kreiswirth B; Kornblum J; Schlievert P
Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus.
Journal of bacteriology 1988;170(9):4365-72.
1988: Majumder S; Novick R P
Intermediates in plasmid pT181 DNA replication.
Nucleic acids research 1988;16(7):2897-912.
1988: Projan S J; Moghazeh S; Novick R P
Nucleotide sequence of pS194, a streptomycin-resistance plasmid from Staphylococcus aureus.
Nucleic acids research 1988;16(5):2179-87.
1988: Kornblum J S; Projan S J; Moghazeh S L; Novick R P
A rapid method to quantitate non-labeled RNA species in bacterial cells.
Gene 1988;63(1):75-85.
1987: Novick R P
Plasmid incompatibility.
Microbiological reviews 1987;51(4):381-95.
1987: Kreiswirth B N; Schlievert P M; Novick R P
Evaluation of coagulase-negative staphylococci for ability to produce toxic shock syndrome toxin 1.
Journal of clinical microbiology 1987;25(10):2028-9.
1987: Wang P Z; Projan S J; Leason K R; Novick R P
Translational fusion with a secretory enzyme as an indicator.
Journal of bacteriology 1987;169(7):3082-7.
1987: Gennaro M L; Kornblum J; Novick R P
A site-specific recombination function in Staphylococcus aureus plasmids.
Journal of bacteriology 1987;169(6):2601-10.
1987: Kreiswirth B N; Handley J P; Schlievert P M; Novick R P
Cloning and expression of streptococcal pyrogenic exotoxin A and staphylococcal toxic shock syndrome toxin-1 in Bacillus subtilis.
Molecular & general genetics : MGG 1987;208(1-2):84-7.
1987: Highlander S K; Novick R P
Plasmid repopulation kinetics in Staphylococcus aureus.
Plasmid 1987;17(3):210-21.
1987: Gruss A D; Ross H F; Novick R P
Functional analysis of a palindromic sequence required for normal replication of several staphylococcal plasmids.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2165-9.
1987: Wang P Z; Novick R P
Nucleotide sequence and expression of the beta-lactamase gene from Staphylococcus aureus plasmid pI258 in Escherichia coli, Bacillus subtilis, and Staphylococcus aureus.
Journal of bacteriology 1987;169(4):1763-6.
1987: Recsei P A; Gruss A D; Novick R P
Cloning, sequence, and expression of the lysostaphin gene from Staphylococcus simulans.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(5):1127-31.
1986: Blomster-Hautamaa D A; Novick R P; Schlievert P M
Localization of biologic functions of toxic shock syndrome toxin-1 by use of monoclonal antibodies and cyanogen bromide-generated toxin fragments.
Journal of immunology (Baltimore, Md. : 1950) 1986;137(11):3572-6.
1986: Kornblum J; Hartman B J; Novick R P; Tomasz A
Conversion of a homogeneously methicillin-resistant strain of Staphylococcus aureus to heterogeneous resistance by Tn551-mediated insertional inactivation.
European journal of clinical microbiology 1986;5(6):714-8.
1986: Blomster-Hautamaa D A; Kreiswirth B N; Kornblum J S; Novick R P; Schlievert P M
The nucleotide and partial amino acid sequence of toxic shock syndrome toxin-1.
The Journal of biological chemistry 1986;261(33):15783-6.
1986: Kreiswirth B N; Kravitz G R; Schlievert P M; Novick R P
Nosocomial transmission of a strain of Staphylococcus aureus causing toxic shock syndrome.
Annals of internal medicine 1986;105(5):704-7.
1986: Novick R P; Edelman I; Lofdahl S
Small Staphylococcus aureus plasmids are transduced as linear multimers that are formed and resolved by replicative processes.
Journal of molecular biology 1986;192(2):209-20.
1986: Gennaro M L; Novick R P
cmp, a cis-acting plasmid locus that increases interaction between replication origin and initiator protein.
Journal of bacteriology 1986;168(1):160-6.
1986: Manch-Citron J N; Gennaro M L; Majumder S; Novick R P
RepC is rate limiting for pT181 plasmid replication.
Plasmid 1986;16(2):108-15.
1986: Projan S J; Novick R P
Incompatibility between plasmids with independent copy control.
Molecular & general genetics : MGG 1986;204(2):341-8.
1986: Hoffman A S; Schwartz H I; Novick R M
Catatonic reaction to accidental haloperidol overdose: an unrecognized drug abuse risk.
The Journal of nervous and mental disease 1986;174(7):428-30.
1986: Blomster-Hautamaa D A; Kreiswirth B N; Novick R P; Schlievert P M
Resolution of highly purified toxic-shock syndrome toxin 1 into two distinct proteins by isoelectric focusing.
Biochemistry 1986;25(1):54-9.
1986: Recsei P; Kreiswirth B; O'Reilly M; Schlievert P; Gruss A; Novick R P
Regulation of exoprotein gene expression in Staphylococcus aureus by agar.
Molecular & general genetics : MGG 1986;202(1):58-61.
1985: de Azavedo J C; Foster T J; Hartigan P J; Arbuthnott J P; O'Reilly M; Kreiswirth B N; Novick R P
Expression of the cloned toxic shock syndrome toxin 1 gene (tst) in vivo with a rabbit uterine model.
Infection and immunity 1985;50(1):304-9.
1985: Novick R P; Murphy E
MLS-resistance determinants in Staphylococcus aureus and their molecular evolution.
The Journal of antimicrobial chemotherapy 1985;16 Suppl A():101-10.
1985: Kumar C C; Novick R P
Plasmid pT181 replication is regulated by two countertranscripts.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(3):638-42.
1985: Projan S J; Kornblum J; Moghazeh S L; Edelman I; Gennaro M L; Novick R P
Comparative sequence and functional analysis of pT181 and pC221, cognate plasmid replicons from Staphylococcus aureus.
Molecular & general genetics : MGG 1985;199(3):452-64.
1985: Novick R P; Projan S J; Kumar C C; Carleton S; Gruss A; Highlander S K; Kornblum J
Replication control for pT181, an indirectly regulated plasmid.
Basic life sciences 1985;30():299-320.
1984: Novick R P; Adler G K; Projan S J; Carleton S; Highlander S K; Gruss A; Khan S A; Iordanescu S
Control of pT181 replication I. The pT181 copy control function acts by inhibiting the synthesis of a replication protein.
The EMBO journal 1984;3(10):2399-405.
1984: Carleton S; Projan S J; Highlander S K; Moghazeh S M; Novick R P
Control of pT181 replication II. Mutational analysis.
The EMBO journal 1984;3(10):2407-14.
1984: Betley M J; Löfdahl S; Kreiswirth B N; Bergdoll M S; Novick R P
Staphylococcal enterotoxin A gene is associated with a variable genetic element.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(16):5179-83.
1984: Projan S J; Novick R P
Reciprocal intrapool variation in plasmid copy numbers: a characteristic of segregational incompatibility.
Plasmid 1984;12(1):52-60.
1984: Kreiswirth B N; O'Reilly M; Novick R P
Genetic characterization and cloning of the toxic shock syndrome exotoxin.
Survey and synthesis of pathology research 1984;3(1):73-82.
1984: Novick R P; Projan S J; Rosenblum W; Edelman I
Staphylococcal plasmid cointegrates are formed by host- and phage-mediated general rec systems that act on short regions of homology.
Molecular & general genetics : MGG 1984;195(1-2):374-7.
1983: Khan S A; Novick R P
Complete nucleotide sequence of pT181, a tetracycline-resistance plasmid from Staphylococcus aureus.
Plasmid 1983;10(3):251-9.
1983: Kreiswirth B N; Löfdahl S; Betley M J; O'Reilly M; Schlievert P M; Bergdoll M S; Novick R P
The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophage.
Nature 1983;305(5936):709-12.
1983: Projan S J; Carleton S; Novick R P
Determination of plasmid copy number by fluorescence densitometry.
Plasmid 1983;9(2):182-90.
1983: Christie P J; Davidson J N; Novick R P; Dunny G M
Effects of tylosin feeding on the antibiotic resistance of selected gram-positive bacteria in pigs.
American journal of veterinary research 1983;44(1):126-8.
1982: Khan S A; Adler G K; Novick R P
Functional origin of replication of pT181 plasmid DNA is contained within a 168-base-pair segment.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(15):4580-4.
1982: Novick R P; Adler G K; Majumder S; Khan S A; Carleton S; Rosenblum W D; Iordanescu S
Coding sequence for the pT181 repC product: a plasmid-coded protein uniquely required for replication.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(13):4108-12.
1982: Kreiswirth B N; Novick R P; Schlievert P M; Bergdoll M
Genetic studies on Staphylococcal strains from patients with toxic shock syndrome.
Annals of internal medicine 1982;96(6 Pt 2):974-7.
1982: Polak J; Novick R P
Closely related plasmids from Staphylococcus aureus and soil bacilli.
Plasmid 1982;7(2):152-62.
1982: Khan S A; Novick R P
Structural analysis of plasmid pSN2 in Staphylococcus aureus: no involvement in enterotoxin B production.
Journal of bacteriology 1982;149(2):642-9.
1981: Krolewski J J; Murphy E; Novick R P; Rush M G
Site-specificity of the chromosomal insertion of Staphylococcus aureus transposon Tn554.
Journal of molecular biology 1981;152(1):19-33.
1981: Novick R P; Iordanescu S; Surdeanu M; Edelman I
Transduction-related cointegrate formation between Staphylococcal plasmids: a new type of site-specific recombination.
Plasmid 1981;6(2):159-72.
1981: Khan S A; Carleton S M; Novick R P
Replication of plasmid pT181 DNA in vitro: requirement for a plasmid-encoded product.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(8):4902-6.
1981: Silver S; Budd K; Leahy K M; Shaw W V; Hammond D; Novick R P; Willsky G R; Malamy M H; Rosenberg H
Inducible plasmid-determined resistance to arsenate, arsenite, and antimony (III) in escherichia coli and Staphylococcus aureus.
Journal of bacteriology 1981;146(3):983-96.
1981: Murphy E; Phillips S; Edelman I; Novick R P
Tn554: isolation and characterization of plasmid insertions.
Plasmid 1981;5(3):292-305.
1981: Novick R P
The development and spread of antibiotic-resistant bacteria as a consequence of feeding antibiotics to livestock.
Annals of the New York Academy of Sciences 1981;368():23-59.
1981: Novick R P; Khan S A; Murphy E; Iordanescu S; Edelman I; Krolewski J; Rush M
Hitchhiking transposons and other mobile genetic elements and site-specific recombination systems in Staphylococcus aureus.
Cold Spring Harbor symposia on quantitative biology 1981;45 Pt 1():67-76.
1980: Novick R P
Plasmids.
Scientific American 1980;243(6):102-4, 106, 110 passim.
1980: Khan S A; Novick R P
Terminal nucleotide sequences of Tn551, a transposon specifying erythromycin resistance in Staphylococcus aureus: homology with Tn3.
Plasmid 1980;4(2):148-54.
1980: el Solh N; Fouace J M; Shalita Z; Bouanchaud D H; Novick R P; Chabbert Y A
Epidemiological and structural studies of Staphylococcus aureus R plasmids mediating resistance to tobramycin and streptogramin.
Plasmid 1980;4(1):117-20.
1980: Shalita Z; Murphy E; Novick R P
Penicillinase plasmids of Staphylococcus aureus: structural and evolutionary relationships.
Plasmid 1980;3(3):291-311.
1980: Murphy E; Novick R P
Site-specific recombination between plasmids of Staphylococcus aureus.
Journal of bacteriology 1980;141(1):316-26.
1979: Murphy E; Novick R P
Physical mapping of Staphylococcus aureus penicillinase plasmid pI524: characterization of an invertible region.
Molecular & general genetics : MGG 1979;175(1):19-30.
1979: Campbell A; Starlinger P; Berg D E; Botstein D; Lederberg E M; Novick R P; Szybalski W
Nomenclature of transposable elements in prokaryotes.
Plasmid 1979;2(3):466-73.
1979: Campbell A; Berg D E; Botstein D; Lederberg E M; Novick R P; Starlinger P; Szybalski W
Nomenclature of transposable elements in prokaryotes.
Gene 1979;5(3):197-206.
1979: Phillips S; Novick R P
Tn554--a site-specific repressor-controlled transposon in Staphylococcus aureus.
Nature 1979;278(5703):476-8.
1979: Novick R P; Murphy E; Gryczan T J; Baron E; Edelman I
Penicillinase plasmids of Staphylococcus aureus: restriction-deletion maps.
Plasmid 1979;2(1):109-29.
1979: Novick R P; Edelman I; Schwesinger M D; Gruss A D; Swanson E C; Pattee P A
Genetic translocation in Staphylococcus aureus.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(1):400-4.
1979: Novick R P; Edelman I; Latta P D; Swanson E C; Pattee P A
Translocatable elements in Staphylococcus aureus.
Contributions to microbiology and immunology 1979;6():41-55.
1979: Novick R P
The molecular basis of the plasmid state.
Contributions to microbiology and immunology 1979;6():1-15.
1978: Novick R P; Hoppensteadt F C
On plasmid incompatibility.
Plasmid 1978;1(4):421-34.
1978: Della Latta P; Bouanchaud D; Novick R P
Partition kinetics and thermosensitive replication of pT169, a naturally occurring multicopy tetracycline resistance plasmid of Staphylococcus aureus.
Plasmid 1978;1(3):366-75.
1977: Pattee P A; Thompson N E; Haubrich D; Novick R P
Chromosomal map locations of integrated plasmids and related elements in Staphylococcus aureus.
Plasmid 1977;1(1):38-51.
1977: Novick R P
The mechanism of translocation in bacteria.
Brookhaven symposia in biology 1977;(29):272-6.
1976: Novick R P; Schwesinger M
Indepencence of plasmid incompatibility and replication control functions in Staphylococcus aureus.
Nature 1976;262(5569):623-6.
1976: Novick R P; Clowes R C; Cohen S N; Curtiss R; Datta N; Falkow S
Uniform nomenclature for bacterial plasmids: a proposal.
Bacteriological reviews 1976;40(1):168-89.
1975: Ruby C; Novick R P
Plasmid interactions in Staphylococcus aureus: nonadditivity of compatible plasmid DNA pools.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(12):5031-5.
1975: Schwesinger M D; Novick R P
Prophage-dependent plasmid integration in Staphylococcus aureus.
Journal of bacteriology 1975;123(2):724-38.
1975: Sheehy R J; Novick R P
Studies on plasmid replication. V Replicative intermediates.
Journal of molecular biology 1975;93(2):237-53.
1974: Wyman L; Goering R V; Novick R P
Genetic control of chromosomal and plasmid recombination in Staphylococcus aureus.
Genetics 1974;76(4):681-702.
1974: Wyman L; Novick R P
Studies on plasmid replication. IV. Complementation of replication-defective mutants by an incompatibility-deficient plasmid.
Molecular & general genetics : MGG 1974;135(2):149-61.
1974: Novick R P
Studies on plasmid replication. III. Isolation and characterization of replication-defective mutants.
Molecular & general genetics : MGG 1974;135(2):131-47.
1973: Novick R P; Smith K; Sheehy R J; Murphy E
A catenated intermediate in plasmid replication.
Biochemical and biophysical research communications 1973;54(4):1460-9.
1973: Lindberg M; Novick R P
Plasmid-specific transformation in Staphylococcus aureus.
Journal of bacteriology 1973;115(1):139-45.
1972: Smith K; Novick R P
Genetic studies on plasmid-linked cadmium resistance in Staphylococcus aureus.
Journal of bacteriology 1972;112(2):761-72.
1972: Novick R P; Brodsky R
Studies on plasmid replication. I. Plasmid incompatibility and establishment in Staphylococcus aureus.
Journal of molecular biology 1972;68(2):285-302.
1971: Novick R P; Bouanchaud D
The problems of drug-resistant pathogenic bacteria. Extrachromosomal nature of drug resistance in Staphylococcus aureus.
Annals of the New York Academy of Sciences 1971;182():279-94.
1969: Rush M G; Gordon C N; Novick R P; Warner R C
Penicillinase plasmid DNA from Staphylococcus aureus.
Proceedings of the National Academy of Sciences of the United States of America 1969;63(4):1304-10.
1969: Novick R P
Extrachromosomal inheritance in bacteria.
Bacteriological reviews 1969;33(2):210-63.
1969: Peyru G; Wexler L F; Novick R P
Naturally occurring penicillinase plasmids in Staphylococcus aureus.
Journal of bacteriology 1969;98(1):215-21.
1969: Novick R P
Staphylococcal plasmids.
Journal of general microbiology 1969;55(3):3.
1968: Peyru G; Novick R P
Streptomycin suppression of plasmid-linked mutations in Staphylococcus aureus.
Journal of bacteriology 1968;96(5):1863-6.
1968: Novick R P; Roth C
Plasmid-linked resistance to inorganic salts in Staphylococcus aureus.
Journal of bacteriology 1968;95(4):1335-42.
1967: Novick R P; Morse S I
In vivo transmission of drug resistance factors between strains of Staphylococcus aureus.
The Journal of experimental medicine 1967;125(1):45-59.
1967: Novick R P
Penicillinase plasmids of Staphylococcus aureus.
Federation proceedings 1967;26(1):29-38.
1965: NOVICK R P; RICHMOND M H
NATURE AND INTERACTIONS OF THE GENETIC ELEMENTS GOVERNING PENICILLINASE SYNTHESIS IN STAPHYLOCOCCUS AUREUS.
Journal of bacteriology 1965;90():467-80.
1965: Novick R P
The genetic determinant of staphylococcal penicillinase.
Annals of the New York Academy of Sciences 1965;128(1):165-82.
1963: NOVICK R P
ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS.
Journal of general microbiology 1963;33():121-36.
1962: NOVICK R P
Staphylococcal penicillinase and the new penicillins.
The Biochemical journal 1962;83():229-35.
1962: NOVICK R P
Micro-iodometric assay for penicillinase.
The Biochemical journal 1962;83():236-40.
1961: NOVICK R P; MAAS W K
Control by endogenously synthesized arginine of the formation of ornithine transcarbamylase in Escherichia coli.
Journal of bacteriology 1961;81():236-40.

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