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Gerben Ferwerda

Research Profile

Chemicals & Drugs

Disorders

Crohn's Disease

Anatomy

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Publications

TOP 3
Hanne K Brand; Ronald de Groot; Gerben Ferwerda; Chris Neeleman; Frank Preijers; Frank J T Staal; Adilia Warris; Peter W M Hermans
CD4+ T-cell counts and interleukin-8 and CCL-5 plasma concentrations discriminate disease severity in children with RSV infection.
Inge Ahout; Gerben Ferwerda; Ronald de Groot
Elucidation and clinical role of emerging viral respiratory tract infections in children.
Marloes Vissers; Dirk J de Jong; Dimitri A Diavatopoulos; Peter W M Hermans; Marije Oosting; Thijs Remijn; Gerben Ferwerda
Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells.

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2013: Hanne K Brand; Ronald de Groot; Gerben Ferwerda; Chris Neeleman; Frank Preijers; Frank J T Staal; Adilia Warris; Peter W M Hermans
CD4+ T-cell counts and interleukin-8 and CCL-5 plasma concentrations discriminate disease severity in children with RSV infection.
Pediatric research 2013;73(2):187-93.
2013: Inge Ahout; Gerben Ferwerda; Ronald de Groot
Elucidation and clinical role of emerging viral respiratory tract infections in children.
Advances in experimental medicine and biology 2013;764():191-204.
2012: Marloes Vissers; Dirk J de Jong; Dimitri A Diavatopoulos; Peter W M Hermans; Marije Oosting; Thijs Remijn; Gerben Ferwerda
Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells.
European journal of immunology 2012;42(10):2727-35.
2012: Kim H Brand; Ronald de Groot; Gerben Ferwerda; Inge M L Ahout; Adilia Warris; Peter W M Hermans
Use of MMP-8 and MMP-9 to assess disease severity in children with viral lower respiratory tract infections.
Journal of medical virology 2012;84(9):1471-80.
2012: Mark Bouwens; Jan J Cuppen; Stan de Kleijn; Gerben Ferwerda; Huub F J Savelkoul; B M Lidy Verburg-van Kemenade
Low-frequency electromagnetic fields do not alter responses of inflammatory genes and proteins in human monocytes and immune cell lines.
Bioelectromagnetics 2012;33(3):226-37.
2012: Stan de Kleijn; Gerben Ferwerda; Peter W M Hermans; Martijn A Huijnen; Matthijs Kox; J Pillay; Iziah Edwin Sama; Johannes G van der Hoeven; Angela van Diepen; Peter Pickkers
Transcriptome kinetics of circulating neutrophils during human experimental endotoxemia.
PloS one 2012;7(6):e38255.
2011: Hector Mora-Montes; Mihai G Netea; Gerben Ferwerda; Megan D Lenardon; Gordon D Brown; Anita R Mistry; Bart Jan Kullberg; Chris A O'Callaghan; Chirag C Sheth; Frank C Odds; Alistair J P Brown; Carol A Munro; Neil A R Gow
Recognition and blocking of innate immunity cells by Candida albicans chitin.
Infection and immunity 2011;79(5):1961-70.
2011: Stan de Kleijn; Mark Bouwens; B M Lidy Verburg-van Kemenade; Jan J M Cuppen; Gerben Ferwerda; Peter W M Hermans
Extremely low frequency electromagnetic field exposure does not modulate toll-like receptor signaling in human peripheral blood mononuclear cells.
Cytokine 2011;54(1):43-50.
2010: Gerben Ferwerda; Mihai G Netea; Leo A B Joosten; Jos W M van der Meer; Luigina Romani; Bart Jan Kullberg
The role of Toll-like receptors and C-type lectins for vaccination against Candida albicans.
Vaccine 2010;28(3):614-22.
2009: Mihai G Netea; Claudia Nold-Petry; Marcel Nold; Leo A B Joosten; Bastian Opitz; Jonathan H M van der Meer; Frank van de Veerdonk; Gerben Ferwerda; Bas Heinhuis; Isabel Devesa; C Joel Funk; Robert J Mason; Bart Jan Kullberg; Anna Rubartelli; Jos W M van der Meer; Charles A Dinarello
Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages.
Blood 2009;113(10):2324-35.
2008: Gerben Ferwerda; Friederike Meyer-Wentrup; Bart Jan Kullberg; Mihai G Netea; Gosse J Adema
Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages.
Cellular microbiology 2008;10(10):2058-66.
2008: Leo A B Joosten; Bas Heinhuis; Shahla Abdollahi-Roodsaz; Gerben Ferwerda; Lionel Lebourhis; Dana J Philpott; Marie-Anne Nahori; Calin Popa; Servaas A Morre; Jos W M van der Meer; Stephen E Girardin; Mihai G Netea; Wim B van den Berg
Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(26):9017-22.
2008: Bart Jan Kullberg; Gerben Ferwerda; Dirk J de Jong; Joost P H Drenth; Leo A B Joosten; Jos W M van der Meer; Mihai G Netea
Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli.
Immunology 2008;123(4):600-5.
2008: Kevin M Dennehy; Gerben Ferwerda; Inês Faro-Trindade; Elwira Pyz; Janet A Willment; Philip R Taylor; Ann Kerrigan; S Vicky Tsoni; Siamon Gordon; Friederike Meyer-Wentrup; Gosse J Adema; Bart Jan Kullberg; Edina Schweighoffer; Victor L J Tybulewicz; Hector Mora-Montes; Neil A R Gow; David L Williams; Mihai G Netea; Gordon D Brown
Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors.
European journal of immunology 2008;38(2):500-6.
2008: Gerben Ferwerda; Matthijs Kramer; Dirk de Jong; Alessandra Piccini; Leo A B Joosten; Isabel Devesaginer; Stephen E Girardin; Gosse J Adema; Jos W M van der Meer; Bart Jan Kullberg; Anna Rubartelli; Mihai G Netea
Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta.
European journal of immunology 2008;38(1):184-91.
2007: Neil A R Gow; Mihai G Netea; Carol A Munro; Gerben Ferwerda; Steven Bates; Hector Mora-Montes; Louise Walker; Trees Jansen; Liesbeth Jacobs; Vicky Tsoni; Gordon D Brown; Frank C Odds; Jos W M van der Meer; Alistair J P Brown; Bart Jan Kullberg
Immune recognition of Candida albicans beta-glucan by dectin-1.
The Journal of infectious diseases 2007;196(10):1565-71.
2007: Gerben Ferwerda; Bart Jan Kullberg; Dirk J de Jong; Stephen E Girardin; Dennis M L Langenberg; Reinout van Crevel; Tom H M Ottenhoff; Jos W M van der Meer; Mihai G Netea
Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2.
Journal of leukocyte biology 2007;82(4):1011-8.
2006: Mihai G Netea; Tania Azam; Gerben Ferwerda; Stephen E Girardin; Soo-Hyun Kim; Charles A Dinarello
Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors.
Journal of leukocyte biology 2006;80(6):1454-61.
2006: Gerben Ferwerda; Stephen E Girardin; Jos W M van der Meer; Mihai G Netea
Normal responses to specific NOD1 ligands.
European journal of immunology 2006;36(10):2817-8; author reply 2818.
2006: Mihai G Netea; Jos W M van der Meer; Gerben Ferwerda; Bart Jan Kullberg
Defective acute inflammation in Crohn's disease.
Lancet 2006;368(9535):577-8.
2006: Mihai G Netea; Neil A R Gow; Carol A Munro; Steven Bates; Claire Collins; Gerben Ferwerda; Richard P Hobson; Gwyneth Bertram; H Bleddyn Hughes; Trees Jansen; Liesbeth Jacobs; Ed T Buurman; Karlijn Gijzen; David L Williams; Ruurd Torensma; Alistair McKinnon; Donna MacCallum; Frank C Odds; Jos W M van der Meer; Alistair J P Brown; Bart Jan Kullberg
Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors.
The Journal of clinical investigation 2006;116(6):1642-50.
2006: Mihai G Netea; Gerben Ferwerda; Chantal A A Van Der Graaf; Jos W M van der Meer; Bart Jan Kullberg
Recognition of fungal pathogens by toll-like receptors.
Current pharmaceutical design 2006;12(32):4195-201.
2005: Mihai G Netea; Tania Azam; Gerben Ferwerda; Stephen E Girardin; Mark Walsh; Jong-Sung Park; Edward Abraham; Jin-Man Kim; Do-Young Yoon; Charles A Dinarello; Soo-Hyun Kim
IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(45):16309-14.
2005: Gerben Ferwerda; Stephen E Girardin; Bart Jan Kullberg; Lionel Le Bourhis; Dirk J de Jong; Dennis M L Langenberg; Reinout van Crevel; Gosse J Adema; Tom H M Ottenhoff; Jos W M van der Meer; Mihai G Netea
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.
PLoS pathogens 2005;1(3):279-85.
2005: Mihai G Netea; Gerben Ferwerda; Dirk J de Jong; Catherine Werts; Ivo G Boneca; Muguette Jéhanno; Jos W M van der Meer; Dominique Mengin-Lecreulx; Philippe J Sansonetti; Dana J Philpott; Sébastien Dharancy; Stephen E Girardin
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists.
The Journal of biological chemistry 2005;280(43):35859-67.
2005: Mihai G Netea; Gerben Ferwerda; Dirk J de Jong; Stephen E Girardin; Bart Jan Kullberg; J W M Van Der Meer
NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype.
The Netherlands journal of medicine 2005;63(8):305-8.
2005: Mihai G Netea; Gerben Ferwerda; Dirk J de Jong; Trees Jansen; Liesbeth Jacobs; Matthijs Kramer; Ton H J Naber; Joost P H Drenth; Stephen E Girardin; Bart Jan Kullberg; Gosse J Adema; Jos W M van der Meer
Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(10):6518-23.
2002: R L West; DP Hirsch; Joep F W M Bartelsman; J de Borst; Gerben Ferwerda; G N J Tytgat; Guy E Boeckxstaens
Long term results of pneumatic dilation in achalasia followed for more than 5 years.
The American journal of gastroenterology 2002;97(6):1346-51.
1999: PJ Blommaart; Gerben Ferwerda; A Kodde; G N J Tytgat; Guy E Boeckxstaens
Nicotinic acetylcholine receptor blocking effect of guanethidine in the rat gastric fundus.
British journal of pharmacology 1999;128(4):903-8.