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Inderjit Singh

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
77
Singh, Avtar
33
Khan, Mushfiquddin
27
Pahan, Kalipada
21
Giri, Shailendra
20
Orak, John
15
Contreras, Miguel
11
Barbosa, Ernest
9
Paintlia, Ajaib
9
Won, Je-Seong
8
Sheikh, Faruk
8
Brown, Frank
8
Gilg, Anne
7
Paintlia, Manjeet
7
Nath, Narender
7
Rattan, Ramandeep

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Publications

TOP 3
Khan Mushfiquddin; Im Yeong-Bin; Shunmugavel Anandakumar; Gilg Anne G; Dhindsa Ramanpreet K; Singh Avtar K; Singh Inderjit
Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact.
Prasad Ratna; Giri Shailendra; Nath Narender; Singh Inderjit; Singh Avtar K
GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions.
Sengupta Tapas K; Leclerc Gilles M; Hsieh-Kinser Ting Ting; Leclerc Guy J; Singh Inderjit; Barredo Julio C
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.

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All Publications

2009: Khan Mushfiquddin; Im Yeong-Bin; Shunmugavel Anandakumar; Gilg Anne G; Dhindsa Ramanpreet K; Singh Avtar K; Singh Inderjit
Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact.
Journal of neuroinflammation 2009;6():32.
2007: Prasad Ratna; Giri Shailendra; Nath Narender; Singh Inderjit; Singh Avtar K
GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions.
Glia 2007;55(1):65-77.
2007: Sengupta Tapas K; Leclerc Gilles M; Hsieh-Kinser Ting Ting; Leclerc Guy J; Singh Inderjit; Barredo Julio C
Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy.
Molecular cancer 2007;6():46.
2006: Qiao Fei; Atkinson Carl; Song Hongbin; Pannu Ravinder; Singh Inderjit; Tomlinson Stephen
Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma.
The American journal of pathology 2006;169(3):1039-47.
2006: Paintlia Ajaib S; Paintlia Manjeet K; Singh Inderjit; Singh Avtar K
Immunomodulatory effect of combination therapy with lovastatin and 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside alleviates neurodegeneration in experimental autoimmune encephalomyelitis.
The American journal of pathology 2006;169(3):1012-25.
2006: Peng Xueyan; Jin Jianping; Giri Shailendra; Montes Monica; Sujkowski Danuta; Tang Yunan; Smrtka Jennifer; Vollmer Timothy; Singh Inderjit; Markovic-Plese Silva
Immunomodulatory effects of 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitors, potential therapy for relapsing remitting multiple sclerosis.
Journal of neuroimmunology 2006;178(1-2):130-9.
2006: Khan Mushfiquddin; Jatana Manu; Elango Chinnasamy; Paintlia Ajaib Singh; Singh Avtar K; Singh Inderjit
Cerebrovascular protection by various nitric oxide donors in rats after experimental stroke.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2006;15(2):114-24.
2006: Prasad Ratna; Giri Shailendra; Nath Narender; Singh Inderjit; Singh Avtar K
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates experimental autoimmune encephalomyelitis via modulation of endothelial-monocyte interaction.
Journal of neuroscience research 2006;84(3):614-25.
2006: Nath Narender; Prasad Ratna; Giri Shailendra; Singh Avtar K; Singh Inderjit
T-bet is essential for the progression of experimental autoimmune encephalomyelitis.
Immunology 2006;118(3):384-91.
2006: Makkar Randhir S; Contreras Miguel A; Paintlia Ajaib S; Smith Brian T; Haq Ehtishamul; Singh Inderjit
Molecular organization of peroxisomal enzymes: protein-protein interactions in the membrane and in the matrix.
Archives of biochemistry and biophysics 2006;451(2):128-40.
2006: Pannu Ravinder; Singh Inderjit
Pharmacological strategies for the regulation of inducible nitric oxide synthase: neurodegenerative versus neuroprotective mechanisms.
Neurochemistry international 2006;49(2):170-82.
2006: Giri S; Khan M; Rattan R; Singh I; Singh A K
Krabbe disease: psychosine-mediated activation of phospholipase A2 in oligodendrocyte cell death.
Journal of lipid research 2006;47(7):1478-92.
2006: Won Je-Seong; Singh Inderjit
Sphingolipid signaling and redox regulation.
Free radical biology & medicine 2006;40(11):1875-88.
2006: Jatana Manu; Singh Inderjit; Singh Avtar K; Jenkins Dorothea
Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats.
Pediatric research 2006;59(5):684-9.
2006: Paintlia Ajaib S; Paintlia Manjeet K; Singh Inderjit; Singh Avtar K
IL-4-induced peroxisome proliferator-activated receptor gamma activation inhibits NF-kappaB trans activation in central nervous system (CNS) glial cells and protects oligodendrocyte progenitors under neuroinflammatory disease conditions: implication for CNS-demyelinating diseases.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(7):4385-98.
2006: Haq Ehtishamul; Contreras Miguel A; Giri Shailendra; Singh Inderjit; Singh Avtar K
Dysfunction of peroxisomes in twitcher mice brain: a possible mechanism of psychosine-induced disease.
Biochemical and biophysical research communications 2006;343(1):229-38.
2006: Rattan R; Giri S; Singh A K; Singh I
Rho/ROCK pathway as a target of tumor therapy.
Journal of neuroscience research 2006;83(2):243-55.
2006: Giri Shailendra; Rattan Ramandeep; Haq Ehtishamul; Khan Mushfiquddin; Yasmin Rifat; Won Je-song; Key Lyndon; Singh Avtar K; Singh Inderjit
AICAR inhibits adipocyte differentiation in 3T3L1 and restores metabolic alterations in diet-induced obesity mice model.
Nutrition & metabolism 2006;3():31.
2006: Jatana Manu; Giri Shailendra; Ansari Mubeen A; Elango Chinnasamy; Singh Avtar K; Singh Inderjit; Khan Mushfiquddin
Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia.
Journal of neuroinflammation 2006;3():12.
2005: Rattan Ramandeep; Giri Shailendra; Singh Avtar K; Singh Inderjit
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibits cancer cell proliferation in vitro and in vivo via AMP-activated protein kinase.
The Journal of biological chemistry 2005;280(47):39582-93.
2005: Ayasolla Kamesh R; Singh Avtar K; Singh Inderjit
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) attenuates the expression of LPS- and Abeta peptide-induced inflammatory mediators in astroglia.
Journal of neuroinflammation 2005;2():21.
2005: Chang Eugene Y; Barbosa Ernest; Paintlia M K; Singh Avtar; Singh Inderjit
The use of N-acetylcysteine for the prevention of hypertension in the reduced uterine perfusion pressure model for preeclampsia in Sprague-Dawley rats.
American journal of obstetrics and gynecology 2005;193(3 Pt 2):952-6.
2005: Paintlia Ajaib S; Paintlia Manjeet K; Khan Mushfiquddin; Vollmer Timothy; Singh Avtar K; Singh Inderjit
HMG-CoA reductase inhibitor augments survival and differentiation of oligodendrocyte progenitors in animal model of multiple sclerosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(11):1407-21.
2005: Nath Narender; Giri Shailendra; Prasad Ratna; Salem Mohamad Labib; Singh Avtar K; Singh Inderjit
5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):566-74.
2005: Prasad Ratna; Giri Shailendra; Nath Narender; Singh Inderjit; Singh Avtar K
Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
Journal of neurochemistry 2005;94(1):204-14.
2005: Won Je-Seong; Im Yeong-Bin; Khan Mushfiquddin; Singh Avtar K; Singh Inderjit
Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells.
Glia 2005;51(1):13-21.
2005: Khan Mushfiquddin; Haq Ehtishamul; Giri Shailendra; Singh Inderjit; Singh Avtar K
Peroxisomal participation in psychosine-mediated toxicity: implications for Krabbe's disease.
Journal of neuroscience research 2005;80(6):845-54.
2005: Pannu Ravinder; Singh Avtar K; Singh Inderjit
A novel role of lactosylceramide in the regulation of tumor necrosis factor alpha-mediated proliferation of rat primary astrocytes. Implications for astrogliosis following neurotrauma.
The Journal of biological chemistry 2005;280(14):13742-51.
2005: Khan Mushfiquddin; Sekhon Bipanjeet; Giri Shailendra; Jatana Manu; Gilg Anne G; Ayasolla Kamesh; Elango Chinnasamy; Singh Avtar K; Singh Inderjit
S-Nitrosoglutathione reduces inflammation and protects brain against focal cerebral ischemia in a rat model of experimental stroke.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(2):177-92.
2005: Pannu Ravinder; Barbosa Ernest; Singh Avtar K; Singh Inderjit
Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats.
Journal of neuroscience research 2005;79(3):340-50.
2005: Lee Jin-Koo; Won Je-Seong; Singh Avtar K; Singh Inderjit
Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.
Neuropharmacology 2005;48(1):151-60.
2004: Kawada Yasusada; Khan Mushfiquddin; Sharma Ashish K; Ratnayake Dinath B; Dobashi Kazushige; Asayama Kohtaro; Moser Hugo W; Contreras Miguel A; Singh Inderjit
Inhibition of peroxisomal functions due to oxidative imbalance induced by mistargeting of catalase to cytoplasm is restored by vitamin E treatment in skin fibroblasts from Zellweger syndrome-like patients.
Molecular genetics and metabolism 2004;83(4):297-305.
2004: Won Je-Seong; Im Yeong-Bin; Singh Avtar K; Singh Inderjit
Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability.
Free radical biology & medicine 2004;37(11):1834-44.
2004: Paintlia Manjeet K; Paintlia Ajaib S; Barbosa Ernest; Singh Inderjit; Singh Avtar K
N-acetylcysteine prevents endotoxin-induced degeneration of oligodendrocyte progenitors and hypomyelination in developing rat brain.
Journal of neuroscience research 2004;78(3):347-61.
2004: Giri Shailendra; Rattan Ramandeep; Singh Avtar K; Singh Inderjit
The 15-deoxy-delta12,14-prostaglandin J2 inhibits the inflammatory response in primary rat astrocytes via down-regulating multiple steps in phosphatidylinositol 3-kinase-Akt-NF-kappaB-p300 pathway independent of peroxisome proliferator-activated receptor gamma.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(8):5196-208.
2004: Singh Inderjit; Paintlia Ajaib S; Khan Mushfiquddin; Stanislaus Romesh; Paintlia Manjeet K; Haq Ehtishamul; Singh Avtar K; Contreras Miguel A
Impaired peroxisomal function in the central nervous system with inflammatory disease of experimental autoimmune encephalomyelitis animals and protection by lovastatin treatment.
Brain research 2004;1022(1-2):1-11.
2004: Lin Angello; Sekhon Charanpal; Sekhon Bipanjeet; Smith Allyson; Chavin Kenneth; Orak John; Singh Inderjit; Singh Avtar
Attenuation of ischemia-reperfusion injury in a canine model of autologous renal transplantation.
Transplantation 2004;78(5):654-9.
2004: Ayasolla Kamesh; Khan Mushfiquddin; Singh Avtar K; Singh Inderjit
Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E.
Free radical biology & medicine 2004;37(3):325-38.
2004: Paintlia Ajaib Singh; Paintlia Manjeet Kaur; Singh Avtar Kaur; Stanislaus Romesh; Gilg Anne Genevieve; Barbosa Ernest; Singh Inderjit
Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin.
Journal of neuroscience research 2004;77(1):63-81.
2004: Pannu Ravinder; Won Je-Seong; Khan Mushfiquddin; Singh Avtar K; Singh Inderjit
A novel role of lactosylceramide in the regulation of lipopolysaccharide/interferon-gamma-mediated inducible nitric oxide synthase gene expression: implications for neuroinflammatory diseases.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(26):5942-54.
2004: Vollmer Timothy; Key Lyndon; Durkalski Valerie; Tyor William; Corboy John; Markovic-Plese Silva; Preiningerova Jana; Rizzo Marco; Singh Inderjit
Oral simvastatin treatment in relapsing-remitting multiple sclerosis.
Lancet 2004;363(9421):1607-8.
2004: Khan Mushfiquddin; Sekhon Bipanjeet; Jatana Manu; Giri Shailendra; Gilg Anne G; Sekhon Charanpal; Singh Inderjit; Singh Avtar K
Administration of N-acetylcysteine after focal cerebral ischemia protects brain and reduces inflammation in a rat model of experimental stroke.
Journal of neuroscience research 2004;76(4):519-27.
2004: Won Je-Seong; Im Yeong-Bin; Khan Mushfiquddin; Singh Avtar K; Singh Inderjit
The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase.
Journal of neurochemistry 2004;88(3):583-93.
2004: Giri Shailendra; Nath Narendra; Smith Brian; Viollet Benoit; Singh Avtar K; Singh Inderjit
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(2):479-87.
2004: Nath Narender; Giri Shailendra; Prasad Ratna; Singh Avtar K; Singh Inderjit
Potential targets of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor for multiple sclerosis therapy.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):1273-86.
2003: Paintlia Ajaib Singh; Gilg Anne Genevieve; Khan Mushfiquddin; Singh Avtar Kaur; Barbosa Ernest; Singh Inderjit
Correlation of very long chain fatty acid accumulation and inflammatory disease progression in childhood X-ALD: implications for potential therapies.
Neurobiology of disease 2003;14(3):425-39.
2003: Rattan Ramandeep; Giri Shailendra; Singh Avtar K; Singh Inderjit
Rho A negatively regulates cytokine-mediated inducible nitric oxide synthase expression in brain-derived transformed cell lines: negative regulation of IKKalpha.
Free radical biology & medicine 2003;35(9):1037-50.
2003: Haq Ehtishamul; Giri Shailendra; Singh Inderjit; Singh Avtar K
Molecular mechanism of psychosine-induced cell death in human oligodendrocyte cell line.
Journal of neurochemistry 2003;86(6):1428-40.
2003: Won Je-Seong; Im Yeong-Bin; Key Lyndon; Singh Inderjit; Singh Avtar K
The involvement of glucose metabolism in the regulation of inducible nitric oxide synthase gene expression in glial cells: possible role of glucose-6-phosphate dehydrogenase and CCAAT/enhancing binding protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(20):7470-8.
2003: Sekhon Bipanjeet; Sekhon Charanpal; Khan Mushfiquddin; Patel Sunil J; Singh Inderjit; Singh Avtar K
N-Acetyl cysteine protects against injury in a rat model of focal cerebral ischemia.
Brain research 2003;971(1):1-8.
2003: Sekhon Charanpal S; Sekhon Bipanjeet K; Singh Inderjit; Orak John K; Singh Avtar K
Attenuation of renal ischemia/reperfusion injury by a triple drug combination therapy.
Journal of nephrology 2003;16(1):63-74.
2002: Dobashi Kazushige; Singh Inderjit; Orak John K; Asayama Kohtaro; Singh Avtar K
Combination therapy of N-acetylcysteine, sodium nitroprusside and phosphoramidon attenuates ischemia-reperfusion injury in rat kidney.
Molecular and cellular biochemistry 2002;240(1-2):9-17.
2002: Stanislaus Romesh; Gilg Anne G; Singh Avtar K; Singh Inderjit
Immunomodulation of experimental autoimmune encephalomyelitis in the Lewis rats by Lovastatin.
Neuroscience letters 2002;333(3):167-70.
2002: Kaul Poonam; Singh Inderjit; Turner Ronald B
Effect of rhinovirus challenge on antioxidant enzymes in respiratory epithelial cells.
Free radical research 2002;36(10):1085-9.
2002: Giri Shailendra; Jatana Manu; Rattan Ramandeep; Won Je-Seong; Singh Inderjit; Singh Avtar K
Galactosylsphingosine (psychosine)-induced expression of cytokine-mediated inducible nitric oxide synthases via AP-1 and C/EBP: implications for Krabbe disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):661-72.
2002: Singh Inderjit
Peroxisomal fatty acid oxidation and cellular redox.
Methods in enzymology 2002;352():361-72.
2001: Stanislaus R; Singh A K; Singh I
Lovastatin treatment decreases mononuclear cell infiltration into the CNS of Lewis rats with experimental allergic encephalomyelitis.
Journal of neuroscience research 2001;66(2):155-62.
2000: Gilg A G; Singh A K; Singh I
Inducible nitric oxide synthase in the central nervous system of patients with X-adrenoleukodystrophy.
Journal of neuropathology and experimental neurology 2000;59(12):1063-9.
2000: Sandhir R; Khan M; Singh I
Identification of the pathway of alpha-oxidation of cerebronic acid in peroxisomes.
Lipids 2000;35(10):1127-33.
2000: Pahan K; Khan M; Singh I
Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase.
Journal of neurochemistry 2000;75(2):576-82.
2000: Ghosh B; Barbosa E; Singh I
Characterization of fibroblast cytoplasmic proteins that bind to the 3' UTR of human catalase mRNA.
Molecular and cellular biochemistry 2000;209(1-2):9-15.
2000: Kaul P; Biagioli M C; Singh I; Turner R B
Rhinovirus-induced oxidative stress and interleukin-8 elaboration involves p47-phox but is independent of attachment to intercellular adhesion molecule-1 and viral replication.
The Journal of infectious diseases 2000;181(6):1885-90.
2000: Pai G S; Khan M; Barbosa E; Key L L; Craver J R; Curé J K; Betros R; Singh I
Lovastatin therapy for X-linked adrenoleukodystrophy: clinical and biochemical observations on 12 patients.
Molecular genetics and metabolism 2000;69(4):312-22.
2000: Dobashi K; Ghosh B; Orak J K; Singh I; Singh A K
Kidney ischemia-reperfusion: modulation of antioxidant defenses.
Molecular and cellular biochemistry 2000;205(1-2):1-11.
2000: Singh I; Carillo O; Namboodiri A
Isolation and biochemical characterization of peroxisomes from cultured rat glial cells.
Neurochemical research 2000;25(2):197-203.
2000: Contreras M A; Khan M; Smith B T; Cimini A M; Gilg A G; Orak J; Singh I; Singh A K
Endotoxin induces structure-function alterations of rat liver peroxisomes: Kupffer cells released factors as possible modulators.
Hepatology (Baltimore, Md.) 2000;31(2):446-55.
2000: Smith B T; Sengupta T K; Singh I
Intraperoxisomal localization of very-long-chain fatty acyl-CoA synthetase: implication in X-adrenoleukodystrophy.
Experimental cell research 2000;254(2):309-20.
2000: Khan M; Contreras M; Singh I
Endotoxin-induced alterations of lipid and fatty acid compositions in rat liver peroxisomes.
Journal of endotoxin research 2000;6(1):41-50.
1999: Pahan K; Dobashi K; Ghosh B; Singh I
Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide.
Journal of neurochemistry 1999;73(2):513-20.
1999: Singh A K; Dobashi K; Gupta M P; Asayama K; Singh I; Orak J K
Manganese superoxide dismutase in rat liver peroxisomes: biochemical and immunochemical evidence.
Molecular and cellular biochemistry 1999;197(1-2):7-12.
1999: Stanislaus R; Pahan K; Singh A K; Singh I
Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin.
Neuroscience letters 1999;269(2):71-4.
1999: Kaul P; Singh I; Turner R B
Effect of nitric oxide on rhinovirus replication and virus-induced interleukin-8 elaboration.
American journal of respiratory and critical care medicine 1999;159(4 Pt 1):1193-8.
1999: Pahan K; Raymond J R; Singh I
Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells.
The Journal of biological chemistry 1999;274(11):7528-36.
1999: Biagioli M C; Kaul P; Singh I; Turner R B
The role of oxidative stress in rhinovirus induced elaboration of IL-8 by respiratory epithelial cells.
Free radical biology & medicine 1999;26(3-4):454-62.
1998: Sandhir R; Khan M; Chahal A; Singh I
Localization of nervonic acid beta-oxidation in human and rodent peroxisomes: impaired oxidation in Zellweger syndrome and X-linked adrenoleukodystrophy.
Journal of lipid research 1998;39(11):2161-71.
1998: Singh I; Khan M; Key L; Pai S
Lovastatin for X-linked adrenoleukodystrophy.
The New England journal of medicine 1998;339(10):702-3.
1998: Singh I; Pahan K; Khan M; Singh A K
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
The Journal of biological chemistry 1998;273(32):20354-62.
1998: Khan M; Pahan K; Singh A K; Singh I
Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy.
Journal of neurochemistry 1998;71(1):78-87.
1998: Chahal A; Khan M; Pai S G; Barbosa E; Singh I
Restoration of phytanic acid oxidation in Refsum disease fibroblasts from patients with mutations in the phytanoyl-CoA hydroxylase gene.
FEBS letters 1998;429(1):119-22.
1998: Pahan K; Khan M; Singh I
Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP.
Journal of lipid research 1998;39(5):1091-100.
1998: Pahan K; Sheikh F G; Namboodiri A M; Singh I
Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages.
The Journal of biological chemistry 1998;273(20):12219-26.
1998: Singh I; Pahan K; Khan M
Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy.
FEBS letters 1998;426(3):342-6.
1998: Yang T; Singh I; Pham H; Sun D; Smart A; Schnermann J B; Briggs J P
Regulation of cyclooxygenase expression in the kidney by dietary salt intake.
The American journal of physiology 1998;274(3 Pt 2):F481-9.
1998: Sheikh F G; Pahan K; Khan M; Barbosa E; Singh I
Abnormality in catalase import into peroxisomes leads to severe neurological disorder.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):2961-6.
1998: Pahan K; Sheikh F G; Khan M; Namboodiri A M; Singh I
Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes.
The Journal of biological chemistry 1998;273(5):2591-600.
1998: Pahan K; Sheikh F G; Namboodiri A M; Singh I
N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes.
Free radical biology & medicine 1998;24(1):39-48.
1997: Pahan K; Sheikh F G; Namboodiri A M; Singh I
Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages.
The Journal of clinical investigation 1997;100(11):2671-9.
1997: Gupta M; Dobashi K; Greene E L; Orak J K; Singh I
Studies on hepatic injury and antioxidant enzyme activities in rat subcellular organelles following in vivo ischemia and reperfusion.
Molecular and cellular biochemistry 1997;176(1-2):337-47.
1997: Singh I; Voigt R G; Sheikh F G; Kremser K; Brown F R
Biochemical features of a patient with Zellweger-like syndrome with normal PTS-1 and PTS-2 peroxisomal protein import systems: a new peroxisomal disease.
Biochemical and molecular medicine 1997;61(2):198-207.
1997: Dobashi K; Pahan K; Chahal A; Singh I
Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells.
Journal of neurochemistry 1997;68(5):1896-903.
1997: Pahan K; Namboodiri A M; Sheikh F G; Smith B T; Singh I
Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes.
The Journal of biological chemistry 1997;272(12):7786-91.
1997: Singh I
Biochemistry of peroxisomes in health and disease.
Molecular and cellular biochemistry 1997;167(1-2):1-29.
1997: Pahan K; Smith B T; Singh A K; Singh I
Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress.
Free radical biology & medicine 1997;23(7):963-71.
1996: Singh I
Mammalian peroxisomes: metabolism of oxygen and reactive oxygen species.
Annals of the New York Academy of Sciences 1996;804():612-27.
1996: Fan C Y; Pan J; Chu R; Lee D; Kluckman K D; Usuda N; Singh I; Yeldandi A V; Rao M S; Maeda N; Reddy J K
Targeted disruption of the peroxisomal fatty acyl-CoA oxidase gene: generation of a mouse model of pseudoneonatal adrenoleukodystrophy.
Annals of the New York Academy of Sciences 1996;804():530-41.
1996: Singh I; Kremser K; Ghosh B; Singh A K; Pai S
Abnormality in translational regulation of catalase expression in disorders of peroxisomal biogenesis.
Journal of neurochemistry 1996;67(6):2373-8.
1996: Contreras M; Sengupta T K; Sheikh F; Aubourg P; Singh I
Topology of ATP-binding domain of adrenoleukodystrophy gene product in peroxisomes.
Archives of biochemistry and biophysics 1996;334(2):369-79.
1996: Yang T; Huang Y G; Singh I; Schnermann J; Briggs J P
Localization of bumetanide- and thiazide-sensitive Na-K-Cl cotransporters along the rat nephron.
The American journal of physiology 1996;271(4 Pt 2):F931-9.
1996: Singh I; Grams M; Wang W H; Yang T; Killen P; Smart A; Schnermann J; Briggs J P
Coordinate regulation of renal expression of nitric oxide synthase, renin, and angiotensinogen mRNA by dietary salt.
The American journal of physiology 1996;270(6 Pt 2):F1027-37.
1996: Pahan K; Khan M; Singh I
Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata.
Journal of lipid research 1996;37(5):1137-43.
1996: Burdette D E; Kremser K; Fink J K; Pahan K; Stanley W; Singh I
Late-onset generalized disorder of peroxisomes.
Neurology 1996;46(3):829-31.
1996: Yang T; Hassan S A; Singh I; Smart A; Brosius F C; Holzman L B; Schnermann J B; Briggs J P
SA gene expression in the proximal tubule of normotensive and hypertensive rats.
Hypertension 1996;27(3 Pt 2):541-51.
1996: Pahan K; Smith B T; Singh I
Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis.
Journal of lipid research 1996;37(1):159-67.
1996: Ghosh B; Hanevold C D; Dobashi K; Orak J K; Singh I
Tissue differences in antioxidant enzyme gene expression in response to endotoxin.
Free radical biology & medicine 1996;21(4):533-40.
1995: Pahan K; Khan M; Smith B T; Singh I
Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation.
FEBS letters 1995;377(2):213-6.
1995: Kremser K; Stangl H; Pahan K; Singh I
Nitric oxide regulates peroxisomal enzyme activities.
European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1995;33(11):763-74.
1995: Ghosh B; Barbosa E; Singh I
Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression.
Molecular and cellular biochemistry 1995;151(1):77-81.
1995: Singh I; Killen P D; Leichtman A B
Cholesterol emboli presenting as acute allograft dysfunction after renal transplantation.
Journal of the American Society of Nephrology : JASN 1995;6(2):165-70.
1995: Cantú E S; Sprinkle T J; Ghosh B; Singh I
The human palmitoyl-CoA ligase (FACL2) gene maps to the chromosome 4q34-q35 region by fluorescence in situ hybridization (FISH) and somatic cell hybrid panels.
Genomics 1995;28(3):600-2.
1995: Pahan K; Singh I
Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes.
Journal of lipid research 1995;36(5):986-97.
1995: Kremser K; Kremser-Jezik M; Singh I
Effect of hypoxia-reoxygenation on peroxisomal functions in cultured human skin fibroblasts from control and Zellweger syndrome patients.
Free radical research 1995;22(1):39-46.
1994: Singh A K; Dhaunsi G S; Gupta M P; Orak J K; Asayama K; Singh I
Demonstration of glutathione peroxidase in rat liver peroxisomes and its intraorganellar distribution.
Archives of biochemistry and biophysics 1994;315(2):331-8.
1994: Pahan K; Gulati S; Singh I
Phytanic acid alpha-oxidation in rat liver mitochondria.
Biochimica et biophysica acta 1994;1201(3):491-7.
1994: Dhaunsi G S; Singh I; Orak J K; Singh A K
Antioxidant enzymes in ciprofibrate-induced oxidative stress.
Carcinogenesis 1994;15(9):1923-30.
1994: Singh I; Dhaunsi G S; Orak J K; Rajagopalan P R; Singh A K
CuZn superoxide dismutase: intraorganellar distribution in peroxisomes.
Annals of the New York Academy of Sciences 1994;723():406-8.
1994: Dhaunsi G S; Hanevold C D; Singh I
Impairment of peroxisomal beta-oxidation system by endotoxin treatment.
Molecular and cellular biochemistry 1994;135(2):187-93.
1994: Contreras M; Mosser J; Mandel J L; Aubourg P; Singh I
The protein coded by the X-adrenoleukodystrophy gene is a peroxisomal integral membrane protein.
FEBS letters 1994;344(2-3):211-5.
1994: Orak J K; Singh A K; Rajagopalan P R; Singh I
Morphological analysis of mitochondrial integrity in prolonged cold renal ischemia utilizing Euro-Collins versus University of Wisconsin preservation solution in a whole organ model.
Transplantation proceedings 1994;26(1):122-5.
1993: Gulati S; Ainol L; Orak J; Singh A K; Singh I
Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney.
Biochimica et biophysica acta 1993;1182(3):291-8.
1993: Pahan K; Singh I
Intraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes.
FEBS letters 1993;333(1-2):154-8.
1993: Singh I; Pahan K; Singh A K; Barbosa E
Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes.
Journal of lipid research 1993;34(10):1755-64.
1993: Singh I; Lazo O; Kremser K
Purification of peroxisomes and subcellular distribution of enzyme activities for activation and oxidation of very-long-chain fatty acids in rat brain.
Biochimica et biophysica acta 1993;1170(1):44-52.
1993: Dhaunsi G S; Singh I; Hanevold C D
Peroxisomal participation in the cellular response to the oxidative stress of endotoxin.
Molecular and cellular biochemistry 1993;126(1):25-35.
1993: Singh I; Gulati S; Orak J K; Singh A K
Expression of antioxidant enzymes in rat kidney during ischemia-reperfusion injury.
Molecular and cellular biochemistry 1993;125(2):97-104.
1993: Lanier S M; Ivkovic B; Singh I; Neumeyer J L; Bakthavachalam V
Visualization of multiple imidazoline/guanidinium-receptive sites.
The Journal of biological chemistry 1993;268(21):16047-51.
1993: Brown F R; Voigt R; Singh A K; Singh I
Peroxisomal disorders. Neurodevelopmental and biochemical aspects.
American journal of diseases of children (1960) 1993;147(6):617-26.
1993: Singh I; Pahan K; Dhaunsi G S; Lazo O; Ozand P
Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz.
The Journal of biological chemistry 1993;268(14):9972-9.
1993: Pahan K; Cofer J; Baliga P; Singh I
Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts.
FEBS letters 1993;322(2):101-4.
1993: Dhaunsi G S; Singh B; Singh A K; Kirschner D A; Singh I
Thioridazine induces lipid peroxidation in myelin of rat brain.
Neuropharmacology 1993;32(2):157-67.
1992: Singh I; Lazo O; Kalipada P; Singh A K
Phytanic acid alpha-oxidation in human cultured skin fibroblasts.
Biochimica et biophysica acta 1992;1180(2):221-4.
1992: Singh I; Lazo O; Dhaunsi G S; Contreras M
Transport of fatty acids into human and rat peroxisomes. Differential transport of palmitic and lignoceric acids and its implication to X-adrenoleukodystrophy.
The Journal of biological chemistry 1992;267(19):13306-13.
1992: Gulati S; Singh A K; Irazu C; Orak J; Rajagopalan P R; Fitts C T; Singh I
Ischemia-reperfusion injury: biochemical alterations in peroxisomes of rat kidney.
Archives of biochemistry and biophysics 1992;295(1):90-100.
1992: Singh I; Lazo O
Peroxisomal enzyme activities in brain and liver of pups of lactating mothers treated with ciprofibrate.
Neuroscience letters 1992;138(2):283-6.
1992: Dhaunsi G S; Gulati S; Singh A K; Orak J K; Asayama K; Singh I
Demonstration of Cu-Zn superoxide dismutase in rat liver peroxisomes. Biochemical and immunochemical evidence.
The Journal of biological chemistry 1992;267(10):6870-3.
1992: Yoshida Y; Singh I; Darby C P
Effect of salicylic acid and calcium on mitochondrial functions.
Acta neurologica Scandinavica 1992;85(3):191-6.
1992: Stanczak H; Stanczak J J; Singh I
Chromosomal localization of the human gene for palmitoyl-CoA ligase (FACL1).
Cytogenetics and cell genetics 1992;59(1):17-9.
1992: Stanczak H; Kremser K; Singh A K; Ashcraft J; Stanley W; Singh I
Complementation in Zellweger syndrome: biochemical analysis of newly generated peroxisomes.
Human heredity 1992;42(3):172-8.
1992: Singh I
Peroxisomal activation, transport and oxidation of fatty acids: implications to peroxisomal disorders.
Progress in clinical and biological research 1992;375():211-22.
1991: Lazo O; Singh A K; Singh I
Postnatal development and isolation of peroxisomes from brain.
Journal of neurochemistry 1991;56(4):1343-53.
1991: Singh I; Lazo O; Contreras M; Stanley W; Hashimoto T
Rhizomelic chondrodysplasia punctata: biochemical studies of peroxisomes isolated from cultured skin fibroblasts.
Archives of biochemistry and biophysics 1991;286(1):277-83.
1991: Lazo O; Contreras M; Singh I
Effect of ciprofibrate on the activation and oxidation of very long chain fatty acids.
Molecular and cellular biochemistry 1991;100(2):159-67.
1990: Lazo O; Contreras M; Singh I
Topographical localization of peroxisomal acyl-CoA ligases: differential localization of palmitoyl-CoA and lignoceroyl-CoA ligases.
Biochemistry 1990;29(16):3981-6.
1990: Lazo O; Contreras M; Yoshida Y; Singh A K; Stanley W; Weise M; Singh I
Cellular oxidation of lignoceric acid is regulated by the subcellular localization of lignoceroyl-CoA ligases.
Journal of lipid research 1990;31(4):583-95.
1990: Yoshida Y; Singh I
Effect of clofibrate on peroxisomal lignoceroyl-CoA ligase activity.
Biochemical medicine and metabolic biology 1990;43(1):22-9.
1990: Bright G M; Singh I
Adrenal autoantibodies bind to adrenal subcellular fractions enriched in cytochrome-c reductase and 5'-nucleotidase.
The Journal of clinical endocrinology and metabolism 1990;70(1):95-9.
1990: Irazu C E; Rajagopalan P R; Orak J K; Fitts C T; Singh I
Mitochondrial membrane fluidity changes in renal ischemia.
Journal of experimental pathology 1990;5(1):1-6.
1990: Dhaunsi G S; Singh A K; Orak J; Singh I
Lipid peroxidation and oxidation of lignoceric acid in kidneys from thioridazine treated rats.
Journal of experimental pathology 1990;5(4):177-86.
1989: Brown F R; Karthigasan J; Singh I; Kirschner D A
X-ray diffraction analysis of myelin lipid/proteolipid protein multilayers.
Journal of neuroscience research 1989;24(2):192-200.
1989: Lazo O; Contreras M; Bhushan A; Stanley W; Singh I
Adrenoleukodystrophy: impaired oxidation of fatty acids due to peroxisomal lignoceroyl-CoA ligase deficiency.
Archives of biochemistry and biophysics 1989;270(2):722-8.
1989: Singh A K; Yoshida Y; Garvin A J; Singh I
Effect of fatty acids and their derivatives on mitochondrial structures.
Journal of experimental pathology 1989;4(1):9-15.
1989: Irazu C E; Ruidera E; Singh I; Orak J K; Fitts C T; Rajagopalan P R
Effect of ischemia and 24 hour reperfusion on ATP synthesis in the rat kidney.
Journal of experimental pathology 1989;4(1):29-36.
1989: Yoshida Y; Singh I; Singh A K; Tecklenberg F W; Brown F R; Darby C P
Reye syndrome: rate of oxidation of fatty acids in leukocytes and serum levels of lipid peroxides.
Journal of experimental pathology 1989;4(3):133-9.
1989: Singh A K; Kulvatunyou N; Singh I; Stanley W S
In situ genetic complementation analysis of cells with generalized peroxisomal dysfunction.
Human heredity 1989;39(5):298-301.
1988: Singh I; Johnson G H; Brown F R
Peroxisomal disorders. Biochemical and clinical diagnostic considerations.
American journal of diseases of children (1960) 1988;142(12):1297-301.
1988: Singh I; Bhushan A; Relan N K; Hashimoto T
Acyl-CoA ligases from rat brain microsomes: an immunochemical study.
Biochimica et biophysica acta 1988;963(3):509-14.
1988: Lazo O; Contreras M; Hashmi M; Stanley W; Irazu C; Singh I
Peroxisomal lignoceroyl-CoA ligase deficiency in childhood adrenoleukodystrophy and adrenomyeloneuropathy.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7647-51.
1988: Ruidera E; Irazu C E; Rajagopalan P R; Orak J K; Fitts C T; Singh I
Fatty acid metabolism in renal ischemia.
Lipids 1988;23(9):882-4.
1988: Chakrabarti A K; Yoshida Y; Powers J M; Singh I; Hogan E L; Banik N L
Calcium-activated neutral proteinase in rat brain myelin and subcellular fractions.
Journal of neuroscience research 1988;20(3):351-8.
1988: Yoshida Y; Fujii M; Brown F R; Singh I
Effect of salicylic acid on mitochondrial-peroxisomal fatty acid catabolism.
Pediatric research 1988;23(3):338-41.
1986: Konat G; Gantt G; Singh I; Hogan E L
Synthesis and acylation of myelin proteolipid protein in quaking mouse brain.
Metabolic brain disease 1986;1(4):241-7.
1986: Hashmi M; Stanley W; Singh I
Lignoceroyl-CoASH ligase: enzyme defect in fatty acid beta-oxidation system in X-linked childhood adrenoleukodystrophy.
FEBS letters 1986;196(2):247-50.
1985: Brown F R; Beck J C; Niebyl J R; Singh I
Effect of proteolipid protein on central nervous system myelin membrane fluidity.
Neuroscience letters 1985;59(2):149-54.
1985: Singh I; Singh R; Bhushan A; Singh A K
Lignoceroyl-CoA ligase activity in rat brain microsomal fraction: topographical localization and effect of detergents and alpha-cyclodextrin.
Archives of biochemistry and biophysics 1985;236(1):418-26.
1984: Moser H W; Moser A E; Singh I; O'Neill B P
Adrenoleukodystrophy: survey of 303 cases: biochemistry, diagnosis, and therapy.
Annals of neurology 1984;16(6):628-41.
1984: Moser H W; Tutschka P J; Brown F R; Moser A E; Yeager A M; Singh I; Mark S A; Kumar A A; McDonnell J M; White C L
Bone marrow transplant in adrenoleukodystrophy.
Neurology 1984;34(11):1410-7.
1984: Singh I; Moser A E; Goldfischer S; Moser H W
Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(13):4203-7.
1984: Moser A E; Singh I; Brown F R; Solish G I; Kelley R I; Benke P J; Moser H W
The cerebrohepatorenal (Zellweger) syndrome. Increased levels and impaired degradation of very-long-chain fatty acids and their use in prenatal diagnosis.
The New England journal of medicine 1984;310(18):1141-6.
1984: Singh I; Moser A E; Moser H W; Kishimoto Y
Adrenoleukodystrophy: impaired oxidation of very long chain fatty acids in white blood cells, cultured skin fibroblasts, and amniocytes.
Pediatric research 1984;18(3):286-90.
1983: Singh I; Singh A K
Degradation of myelin proteins by brain endogenous neutral protease.
Neuroscience letters 1983;39(1):77-82.
1983: Singh I
Ceramide synthesis from free fatty acids in rat brain: function of NADPH and substrate specificity.
Journal of neurochemistry 1983;40(6):1565-70.
1983: Singh I; Kishimoto Y
Effect of cyclodextrins on the solubilization of lignoceric acid, ceramide, and cerebroside, and on the enzymatic reactions involving these compounds.
Journal of lipid research 1983;24(5):662-5.
1982: Brown F R; McAdams A J; Cummins J W; Konkol R; Singh I; Moser A B; Moser H W
Cerebro-hepato-renal (Zellweger) syndrome and neonatal adrenoleukodystrophy: similarities in phenotype and accumulation of very long chain fatty acids.
The Johns Hopkins medical journal 1982;151(6):344-51.
1982: Uda M; Shiojima K; Shigematsu H; Singh I; Kishimoto Y
Purification of the heat-stable factor required for alpha-hydroxylation and beta-oxidation of very long chain fatty acids in brain.
Archives of biochemistry and biophysics 1982;216(1):186-95.
1982: Singh I; Kishimoto Y
Brain-specific ceramide synthesis activity: change during brain maturation and in jimpy mouse brain.
Brain research 1982;232(2):500-5.
1981: Singh I; Moser H W; Moser A B; Kishimoto Y
Adrenoleukodystrophy: impaired oxidation of long chain fatty acids in cultured skin fibroblasts an adrenal cortex.
Biochemical and biophysical research communications 1981;102(4):1223-9.
1981: Yahara S; Singh I; Kishimoto Y
Levels and syntheses of cerebrosides and sulfatides in subcellular fractions of jimpy mutants.
Neurochemical research 1981;6(8):885-92.
1981: Singh I; Kishimoto Y
alpha-Hydroxylation of fatty acids in brain: characterization of heat-labile factor.
Journal of neurochemistry 1981;37(2):388-91.
1981: Uda M; Singh I; Kishimoto Y
Glutamate formed from lignoceric acid by rat brain preparation in the presence of pyridine nucleotide and cytosolic factors: a brain-specific oxidation of very long chain fatty acids.
Biochemistry 1981;20(5):1295-300.
1980: Tennekoon G I; Kishimoto Y; Singh I; Nonaka G; Bourre J M
The differentiation of oligodendrocytes in the rat optic nerve.
Developmental biology 1980;79(1):149-58.
1980: Yahara S; Singh I; Kishimoto Y
Cerebroside and cerebroside III-sulfate in brain cytosol: evidence for their involvement in myelin assembly.
Biochimica et biophysica acta 1980;619(2):177-85.
1980: Singh I; Kishimoto Y
Ceramide synthesis in rat brain: characterization of the synthesis requiring pyridine nucleotide.
Archives of biochemistry and biophysics 1980;202(1):93-100.
1979: Kishimoto Y; Akanuma H; Singh I
Fatty acid alpha-hydroxylation and its relation to myelination.
Molecular and cellular biochemistry 1979;28(1-3):93-105.
1979: Singh I; Kishimoto Y
Alpha hydroxylation of lignoceric acid in brain. Subcellular localization of alpha hydroxylation and the requirement for heat-stable and heat-labile factors and sphingosine.
The Journal of biological chemistry 1979;254(16):7698-704.
1979: Singh I; Kishimoto Y; Vunnam R R; Radin N S
Conversion by rat brain preparation of lignoceric acid to ceramides and cerebrosides containing both alpha-hydroxy and nonhydroxy fatty acids. Effects of compounds which affect sphingolipid metabolism.
The Journal of biological chemistry 1979;254(10):3840-4.
1978: Singh I; Kishimoto Y
A novel synthesis of ceramide from lignoceric acid and sphingosine by rat brain preparation; the amide formation requires a pyridine nucleotide.
Biochemical and biophysical research communications 1978;82(4):1287-93.

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