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Zoltan N. Oltvai

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TOP 3
Basak Isin; Guillermina Estiu; Olaf Wiest; Zoltan N. Oltvai
Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.
Basak Isin; Judith Klein-Seetharaman; Zoltan N. Oltvai; Kalyan C Tirupula; Ivet Bahar
Identification of motions in membrane proteins by elastic network models and their experimental validation.
S T Henriksen; J Liu; Guillermina Estiu; Zoltan N. Oltvai; Olaf Wiest
Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays.

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All Publications

2012: Basak Isin; Guillermina Estiu; Olaf Wiest; Zoltan N. Oltvai
Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes.
PloS one 2012;7(12):e50186.
2012: Basak Isin; Judith Klein-Seetharaman; Zoltan N. Oltvai; Kalyan C Tirupula; Ivet Bahar
Identification of motions in membrane proteins by elastic network models and their experimental validation.
Methods in molecular biology (Clifton, N.J.) 2012;914():285-317.
2010: S T Henriksen; J Liu; Guillermina Estiu; Zoltan N. Oltvai; Olaf Wiest
Identification of novel bacterial histidine biosynthesis inhibitors using docking, ensemble rescoring, and whole-cell assays.
Bioorganic & medicinal chemistry 2010;18(14):5148-56.
2010: Y Shen; J Liu; Guillermina Estiu; B Isin; Y-Y Ahn; D-S Lee; Albert-László Barabási; V Kapatral; Olaf Wiest; Zoltan N. Oltvai
Blueprint for antimicrobial hit discovery targeting metabolic networks.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(3):1082-7.
2009: Deok-Sun Lee; Henry Burd; Jiangxia Liu; Eivind Almaas; Olaf Wiest; Albert-László Barabási; Zoltan N. Oltvai; Vinayak Kapatral
Comparative genome-scale metabolic reconstruction and flux balance analysis of multiple Staphylococcus aureus genomes identify novel antimicrobial drug targets.
Journal of bacteriology 2009;191(12):4015-24.
2009: Jesper N Tegnér; Albert Compte; Charles Auffray; Gary An; Gunnar Cedersund; Gilles Clermont; Boris Gutkin; Zoltan N. Oltvai; Klaas Enno Stephan; Randy Thomas; Pablo Villoslada
Computational disease modeling - fact or fiction?
BMC systems biology 2009;3():56.
2008: Alexei Vazquez; Marcio A de Menezes; Albert-László Barabási; Zoltan N. Oltvai
Impact of limited solvent capacity on metabolic rate, enzyme activities, and metabolite concentrations of S. cerevisiae glycolysis.
PLoS computational biology 2008;4(10):e1000195.
2008: D-S Lee; J Park; K A Kay; N A Christakis; Zoltan N. Oltvai; Albert-László Barabási
The implications of human metabolic network topology for disease comorbidity.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):9880-5.
2008: Jason Ernst; Qasim Beg; Krin A Kay; Gábor Balázsi; Zoltan N. Oltvai; Ziv Bar-Joseph
A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli.
PLoS computational biology 2008;4(3):e1000044.
2008: Alexei Vazquez; Qasim Beg; Marcio A Demenezes; Jason Ernst; Ziv Bar-Joseph; Albert-László Barabási; László G Boros; Zoltan N. Oltvai
Impact of the solvent capacity constraint on E. coli metabolism.
BMC systems biology 2008;2():7.
2007: Qasim Beg; A Vazquez; Jason Ernst; M Argollo de Menezes; Ziv Bar-Joseph; Albert-László Barabási; Zoltan N. Oltvai
Intracellular crowding defines the mode and sequence of substrate uptake by Escherichia coli and constrains its metabolic activity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(31):12663-8.
2007: Réka Albert; Zoltan N. Oltvai
Shaping specificity in signaling networks.
Nature genetics 2007;39(3):286-7.
2007: Gábor Balázsi; Zoltan N. Oltvai
A pitfall in series of microarrays: the position of probes affects the cross-correlation of gene expression profiles.
Methods in molecular biology (Clifton, N.J.) 2007;377():153-62.
2006: Illés J Farkas; Qasim Beg; Zoltan N. Oltvai
Exploring transcriptional regulatory networks in the worm.
Cell 2006;125(6):1032-4.
2006: Illés J Farkas; Chuang Wu; Chakra Chennubhotla; Ivet Bahar; Zoltan N. Oltvai
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae.
BMC bioinformatics 2006;7():478.
2005: Eivind Almaas; Zoltan N. Oltvai; Albert-László Barabási
The activity reaction core and plasticity of metabolic networks.
PLoS computational biology 2005;1(7):e68.
2005: Gábor Balázsi; Albert-László Barabási; Zoltan N. Oltvai
Topological units of environmental signal processing in the transcriptional regulatory network of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(22):7841-6.
2005: Gábor Balázsi; Zoltan N. Oltvai
Sensing your surroundings: how transcription-regulatory networks of the cell discern environmental signals.
Science's STKE : signal transduction knowledge environment 2005;2005(282):pe20.
2004: A Vázquez; R Dobrin; Danilo Sergi; jean-pierre eckmann; Zoltan N. Oltvai; Albert-László Barabási
The topological relationship between the large-scale attributes and local interaction patterns of complex networks.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):17940-5.
2004: Xin Tong; John W Campbell; Gábor Balázsi; Krin A Kay; Barry L Wanner; Svetlana Y Gerdes; Zoltan N. Oltvai
Genome-scale identification of conditionally essential genes in E. coli by DNA microarrays.
Biochemical and biophysical research communications 2004;322(1):347-54.
2004: Soon-Hyung Yook; Zoltan N. Oltvai; Albert-László Barabási
Functional and topological characterization of protein interaction networks.
Proteomics 2004;4(4):928-42.
2004: Eivind Almaas; B Kovács; Tamás Vicsek; Zoltan N. Oltvai; Albert-László Barabási
Global organization of metabolic fluxes in the bacterium Escherichia coli.
Nature 2004;427(6977):839-43.
2004: Albert-László Barabási; Zoltan N. Oltvai
Network biology: understanding the cell's functional organization.
Nature reviews. Genetics 2004;5(2):101-13.
2004: Radu Dobrin; Qasim Beg; Albert-László Barabási; Zoltan N. Oltvai
Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network.
BMC bioinformatics 2004;5():10.
2003: Zoltán Dezso; Zoltan N. Oltvai; Albert-László Barabási
Bioinformatics analysis of experimentally determined protein complexes in the yeast Saccharomyces cerevisiae.
Genome research 2003;13(11):2450-4.
2003: Svetlana Y Gerdes; M D Scholle; John W Campbell; Gábor Balázsi; Erzsébet Ravasz; Matthew D Daugherty; A L Somera; Nikos Kyrpides; Iain Anderson; M S Gelfand; A Bhattacharya; Vinayak Kapatral; Mark D'Souza; Mark V Baev; Yuri Grechkin; Faika Mseeh; Michael Fonstein; Ross Overbeek; A-L Barabási; Zoltan N. Oltvai; Andrei Osterman
Experimental determination and system level analysis of essential genes in Escherichia coli MG1655.
Journal of bacteriology 2003;185(19):5673-84.
2003: Stefan Wuchty; Zoltan N. Oltvai; Albert-László Barabási
Evolutionary conservation of motif constituents in the yeast protein interaction network.
Nature genetics 2003;35(2):176-9.
2003: E V Ariztia; V Subbarao; Dennis B Solt; Alfred W Rademaker; A P Iyer; Zoltan N. Oltvai
Osteopontin contributes to hepatocyte growth factor-induced tumor growth and metastasis formation.
Experimental cell research 2003;288(2):257-67.
2003: Gábor Balázsi; Krin A Kay; Albert-László Barabási; Zoltan N. Oltvai
Spurious spatial periodicity of co-expression in microarray data due to printing design.
Nucleic acids research 2003;31(15):4425-33.
2003: Bálint Tombor; Mary Kathleen Rundell; Zoltan N. Oltvai
Bcl-2 promotes premature senescence induced by oncogenic Ras.
Biochemical and biophysical research communications 2003;303(3):800-7.
2002: Zoltan N. Oltvai; Albert-László Barabási
Systems biology. Life's complexity pyramid.
Science (New York, N.Y.) 2002;298(5594):763-4.
2002: Erzsébet Ravasz; A L Somera; D A Mongru; Zoltan N. Oltvai; Albert-László Barabási
Hierarchical organization of modularity in metabolic networks.
Science (New York, N.Y.) 2002;297(5586):1551-5.
2001: J Podani; Zoltan N. Oltvai; Hawoong Jeong; Bálint Tombor; Albert-László Barabási; E Szathmáry
Comparable system-level organization of Archaea and Eukaryotes.
Nature genetics 2001;29(1):54-6.
2001: Hawoong Jeong; S P Mason; Albert-László Barabási; Zoltan N. Oltvai
Lethality and centrality in protein networks.
Nature 2001;411(6833):41-2.
2000: Hawoong Jeong; Bálint Tombor; R Albert; Zoltan N. Oltvai; Albert-László Barabási
The large-scale organization of metabolic networks.
Nature 2000;407(6804):651-4.
1999: P B Poommipanit; B Chen; Zoltan N. Oltvai
Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.
The Journal of biological chemistry 1999;274(2):1033-9.
1997: E G St Clair; S J Anderson; Zoltan N. Oltvai
Bcl-2 counters apoptosis by Bax heterodimerization-dependent and -independent mechanisms in the T-cell lineage.
The Journal of biological chemistry 1997;272(46):29347-55.
1996: A R Gottschalk; Lawrence Boise; Zoltan N. Oltvai; M A Accavitti; S J Korsmeyer; J Quintáns; Craig Thompson
The ability of Bcl-x(L) and Bcl-2 to prevent apoptosis can be differentially regulated.
Cell death and differentiation 1996;3(1):113-8.
1995: Thomas W Sedlak; Zoltan N. Oltvai; E Yang; K Wang; Lawrence Boise; Craig Thompson; Stanley J Korsmeyer
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7834-8.
1995: Stanley J Korsmeyer; X M Yin; Zoltan N. Oltvai; D J Veis-Novack; G P Linette
Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family.
Biochimica et biophysica acta 1995;1271(1):63-6.
1995: X M Yin; Zoltan N. Oltvai; Stanley J Korsmeyer
Heterodimerization with Bax is required for Bcl-2 to repress cell death.
Current topics in microbiology and immunology 1995;194():331-8.
1994: Zoltan N. Oltvai; S J Korsmeyer
Checkpoints of dueling dimers foil death wishes.
Cell 1994;79(2):189-92.
1994: Mai Nguyen; Philip E Branton; P A Walton; Zoltan N. Oltvai; S J Korsmeyer; Gordon C Shore
Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.
The Journal of biological chemistry 1994;269(24):16521-4.
1994: X M Yin; Zoltan N. Oltvai; Stanley J Korsmeyer
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.
Nature 1994;369(6478):321-3.
1994: X M Yin; Zoltan N. Oltvai; D J Veis-Novack; G P Linette; Stanley J Korsmeyer
Bcl-2 gene family and the regulation of programmed cell death.
Cold Spring Harbor symposia on quantitative biology 1994;59():387-93.
1993: Stanley J Korsmeyer; J R Shutter; D J Veis; D E Merry; Zoltan N. Oltvai
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.
Seminars in cancer biology 1993;4(6):327-32.
1993: David M Hockenbery; Zoltan N. Oltvai; X M Yin; C L Milliman; Stanley J Korsmeyer
Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
Cell 1993;75(2):241-51.
1993: Zoltan N. Oltvai; C L Milliman; Stanley J Korsmeyer
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
Cell 1993;74(4):609-19.
1991: Zoltan N. Oltvai; E C Wong; J P Atkinson; K S Tung
C1 inhibitor deficiency: molecular and immunologic basis of hereditary and acquired angioedema.
Laboratory investigation; a journal of technical methods and pathology 1991;65(4):381-8.