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Linda M. Resar

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Sandeep N Shah; Saraswati Sukumar; C Conover Talbot; Sujayita Roy; Amy Belton; Leslie Cope; David L Huso; Weijie Poh; Linda M. Resar
HMGA1: A Master Regulator of Tumor Progression in Triple-Negative Breast Cancer Cells.
Joelle Anne Hillion; David L Huso; Tait Huso; Collins Karikari; Anirban Maitra; Dwella Moton Nelson; Abimbola Aderinto; Amy Belton; Nathaniel Campbell; Leslie Cope; Francescopaolo Di Cello; Andrew Schuldenfrei; Sandeep N Shah; Shamayra S Smail; Linda M. Resar
The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma.
Sandeep N Shah; Linda M. Resar
High mobility group A1 and cancer: potential biomarker and therapeutic target.

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All Publications

2013: Sandeep N Shah; Saraswati Sukumar; C Conover Talbot; Sujayita Roy; Amy Belton; Leslie Cope; David L Huso; Weijie Poh; Linda M. Resar
HMGA1: A Master Regulator of Tumor Progression in Triple-Negative Breast Cancer Cells.
PloS one 2013;8(5):e63419.
2012: Joelle Anne Hillion; David L Huso; Tait Huso; Collins Karikari; Anirban Maitra; Dwella Moton Nelson; Abimbola Aderinto; Amy Belton; Nathaniel Campbell; Leslie Cope; Francescopaolo Di Cello; Andrew Schuldenfrei; Sandeep N Shah; Shamayra S Smail; Linda M. Resar
The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2012;12(4):372-9.
2012: Sandeep N Shah; Linda M. Resar
High mobility group A1 and cancer: potential biomarker and therapeutic target.
Histology and histopathology 2012;27(5):567-79.
2012: Sandeep N Shah; ELIAS ZAMBIDIS; Amy Belton; Leslie Cope; Joelle Anne Hillion; David L Huso; Candace Kerr; Cyndi Liu; Linda M. Resar
HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.
PloS one 2012;7(11):e48533.
2012: Amy Belton; Alexander Gabrovsky; David L Huso; Christine A Iacobuzio-Donahue; Ray Reeves; Young Kyung Bae; Linda M. Resar
HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells.
PloS one 2012;7(1):e30034.
2011: Alison R Moliterno; Linda M. Resar
AKNA: another AT-hook transcription factor "hooking-up" with inflammation.
Cell research 2011;21(11):1528-30.
2011: Dwella M Nelson; Joelle Anne Hillion; Biju Joseph; Judith E Karp; Jodi Segal; Linda M. Resar
Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia.
Leukemia & lymphoma 2011;52(10):1999-2006.
2011: Linda M. Resar; Robert A Brodsky
"Let"-ing go with clonal expansion?
Blood 2011;117(22):5788-90.
2011: Judith E Karp; B Douglas Smith; Linda M. Resar; Jacqueline M Greer; Amanda Blackford; Ming Zhao; Dwella Moton-Nelson; Katrina Alino; Mark Levis; Steven D Gore; Biju Joseph; Hetty Carraway; A MICHAEL MCDEVITT; Lorena Bagain; Karen Mackey; Janet Briel; L Austin Doyle; John J Wright; MICHELLE RUDEK-RENAUT
Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias.
Blood 2011;117(12):3302-10.
2011: Bin-Kuan Chou; Prashant Mali; Xiaosong Huang; Zhaohui Ye; Sarah N Dowey; Linda M. Resar; Chunlin Zou; Y Alex Zhang; Jay Tong; Linzhao Cheng
Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures.
Cell research 2011;21(3):518-29.
2011: Andrew Schuldenfrei; C Conover Talbot; Jeanne Kowalski; Weijie Poh; Sandeep N Shah; Amy Belton; Francescopaolo Di Cello; Hua-Ling Tsai; David L Huso; Tait H Huso; Linda M. Resar
HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis.
BMC genomics 2011;12():549.
2010: Parisa Mazaheri; Girish Nadkarni; Elizabeth Lowe; Patrick Hines; Milena Vuica; Matthew Griffin; Linda M. Resar
Ghosal hematodiaphyseal dysplasia: a rare cause of a myelophthisic anemia.
Pediatric blood & cancer 2010;55(6):1187-90.
2010: Linda M. Resar
The high mobility group A1 gene: transforming inflammatory signals into cancer?
Cancer research 2010;70(2):436-9.
2010: Alexandra C Hristov; Leslie Cope; Francescopaolo Di Cello; Marcelo Delos Reyes; Mansher Singh; Joelle Anne Hillion; Amy Belton; Biju Joseph; Andrew Schuldenfrei; Christine A Iacobuzio-Donahue; Anirban Maitra; Linda M. Resar
HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(1):98-104.
2010: Alexander Gabrovsky; Abimbola Aderinto; Abimbole Aderinto; MELISSA SPEVAK; Elliot Vichinsky; Linda M. Resar
Low dose, oral epsilon aminocaproic acid for renal papillary necrosis and massive hemorrhage in hemoglobin SC disease.
Pediatric blood & cancer 2010;54(1):148-50.
2009: Joelle Anne Hillion; Lisa J Wood; Mita Mukherjee; Raka Bhattacharya; Francescopaolo Di Cello; Jeanne Kowalski; Ossama Elbahloul; Jodi Segal; John Poirier; Charles Rudin; Surajit Dhara; Amy Belton; Biju Joseph; Stanley Zucker; Linda M. Resar
Upregulation of MMP-2 by HMGA1 promotes transformation in undifferentiated, large-cell lung cancer.
Molecular cancer research : MCR 2009;7(11):1803-12.
2009: Alexandra C Hristov; Leslie Cope; Marcelo Delos Reyes; Mansher Singh; Christine A Iacobuzio-Donahue; Anirban Maitra; Linda M. Resar
HMGA2 protein expression correlates with lymph node metastasis and increased tumor grade in pancreatic ductal adenocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2009;22(1):43-9.
2008: Joelle Anne Hillion; Surajit Dhara; Takita Felder Sumter; Mita Mukherjee; Francescopaolo Di Cello; Amy Belton; James Turkson; Souyma Jaganathan; Linzhao Cheng; Zhaohui Ye; Richard Jove; Peter Aplan; Ying-Wei Lin; Kelsey Wertzler; Ray Reeves; Ossama Elbahlouh; Jeanne Kowalski; Raka Bhattacharya; Linda M. Resar
The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?
Cancer research 2008;68(24):10121-7.
2008: Francescopaolo Di Cello; Joelle Anne Hillion; Jeanne Kowalski; Brigitte M Ronnett; Abimbola Aderinto; David L Huso; Linda M. Resar
Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts.
Molecular cancer therapeutics 2008;7(7):2090-5.
2008: Francescopaolo Di Cello; Joelle Anne Hillion; Alexandra Hristov; Lisa J Wood; Mita Mukherjee; Andrew Schuldenfrei; Jeanne Kowalski; Raka Bhattacharya; Raheela Ashfaq; Linda M. Resar
HMGA2 participates in transformation in human lung cancer.
Molecular cancer research : MCR 2008;6(5):743-50.
2008: Patrick Hines; George J Dover; Linda M. Resar
Pulsed-dosing with oral sodium phenylbutyrate increases hemoglobin F in a patient with sickle cell anemia.
Pediatric blood & cancer 2008;50(2):357-9.
2007: William J Savage; Patricia A DeRusso; Linda M. Resar; Allen R Chen; Meghan A Higman; David M Loeb; Richard J Jones; Robert A Brodsky
Treatment of hepatitis-associated aplastic anemia with high-dose cyclophosphamide.
Pediatric blood & cancer 2007;49(7):947-51.
2007: Abeba Tesfaye; Francescopaolo Di Cello; Joelle Anne Hillion; Brigitte M Ronnett; Ossama Elbahloul; Raheela Ashfaq; Surajit Dhara; Edward Prochownik; Kathryn Tworkoski; Raymond Reeves; Richard B S Roden; Lora Hedrick Ellenson; David L Huso; Linda M. Resar
The high-mobility group A1 gene up-regulates cyclooxygenase 2 expression in uterine tumorigenesis.
Cancer research 2007;67(9):3998-4004.
2006: Monica L Hulbert; Douglas J Scothorn; Julie Panepinto; J Paul Scott; George R Buchanan; Sharada A Sarnaik; robert joseph fallon; Jen-Yih Chu; Winfred Wang; James F Casella; Linda M. Resar; Brian Berman; Thomas Adamkiewicz; Lewis Hsu; Kim Smith-Whitley; Donald Mahoney; Gerald Woods; Masayo Watanabe; Michael R DeBaun
Exchange blood transfusion compared with simple transfusion for first overt stroke is associated with a lower risk of subsequent stroke: a retrospective cohort study of 137 children with sickle cell anemia.
The Journal of pediatrics 2006;149(5):710-2.
2004: Natsuki Takaha; Linda M. Resar; Don Vindivich; Donald S Coffey
High mobility group protein HMGI(Y) enhances tumor cell growth, invasion, and matrix metalloproteinase-2 expression in prostate cancer cells.
The Prostate 2004;60(2):160-7.
2004: Arindam Dhar; Jing Hu; Raymond Reeves; Linda M. Resar; Nancy H Colburn
Dominant-negative c-Jun (TAM67) target genes: HMGA1 is required for tumor promoter-induced transformation.
Oncogene 2004;23(25):4466-76.
2004: Yi Xu; Takita Felder Sumter; Raka Bhattacharya; Abeba Tesfaye; Ephraim J Fuchs; Lisa J Wood; David L Huso; Linda M. Resar
The HMG-I oncogene causes highly penetrant, aggressive lymphoid malignancy in transgenic mice and is overexpressed in human leukemia.
Cancer research 2004;64(10):3371-5.
2004: Fumihiro Hommura; Motoo Katabami; Virna D Leaner; Howard Donninger; Takita F Sumter; Linda M. Resar; Michael J Birrer
HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
Molecular cancer research : MCR 2004;2(5):305-14.
2004: Jodi Segal; Edgar R Miller; Nga Hong Brereton; Linda M. Resar
Concentrations of B vitamins and homocysteine in children with sickle cell anemia.
Southern medical journal 2004;97(2):149-55.
2004: Ding-You Li; ANN SCHEIMANN; J Glenn Songer; Richard E Person; Marshall Horwitz; Linda M. Resar; Kathleen B Schwarz
Enteritis necroticans with recurrent enterocutaneous fistulae caused by Clostridium perfringens in a child with cyclic neutropenia.
Journal of pediatric gastroenterology and nutrition 2004;38(2):213-5.
2002: Linda M. Resar; Jodi Segal; Lorna K Fitzpatric; Alison Friedmann; Saul W Brusilow; George J Dover
Induction of fetal hemoglobin synthesis in children with sickle cell anemia on low-dose oral sodium phenylbutyrate therapy.
Journal of pediatric hematology/oncology 2002;24(9):737-41.
2002: Christine E Dolde; Mita Mukherjee; Cecilia Cho; Linda M. Resar
HMG-I/Y in human breast cancer cell lines.
Breast cancer research and treatment 2002;71(3):181-91.
2001: Marisa L Pedulla; Nathan R Treff; Linda M. Resar; Raymond Reeves
Sequence and analysis of the murine Hmgiy (Hmga1) gene locus.
Gene 2001;271(1):51-8.
2000: Lisa J Wood; JF Maher; Tracie E Bunton; Linda M. Resar
The oncogenic properties of the HMG-I gene family.
Cancer research 2000;60(15):4256-61.
2000: Lisa J Wood; M Mukherjee; Christine E Dolde; Yi Xu; JF Maher; Tracie E Bunton; J B Williams; Linda M. Resar
HMG-I/Y, a new c-Myc target gene and potential oncogene.
Molecular and cellular biology 2000;20(15):5490-502.
1999: Chi Dang; Linda M. Resar; Eileen Sproat Emison; S Kim; Q Li; Julia E Prescott; Diane R Wonsey; Karen I Zeller
Function of the c-Myc oncogenic transcription factor.
Experimental cell research 1999;253(1):63-77.
1998: J Rice; Linda M. Resar
Hematologic abnormalities associated with influenza A infection: a report of 3 cases.
The American journal of the medical sciences 1998;316(6):401-3.
1998: A M Friedmann; Karen E King; R Sue Shirey; Linda M. Resar; James F Casella
Fatal autoimmune hemolytic anemia in a child due to warm-reactive immunoglobulin M antibody.
Journal of pediatric hematology/oncology 1998;20(5):502-5.
1998: Michael R DeBaun; Jeffrey Schatz; M J Siegel; Myles Koby; Suzanne Craft; Linda M. Resar; Jen-Yih Chu; G Launius; M Dadash-Zadeh; R B Lee; Michael J Noetzel
Cognitive screening examinations for silent cerebral infarcts in sickle cell disease.
Neurology 1998;50(6):1678-82.
1998: Linda M. Resar; Mark A Helfaer
Recurrent seizures in a neonate after lidocaine administration.
Journal of perinatology : official journal of the California Perinatal Association 1998;18(3):193-5.
1997: M A Pelidis; Gregory Kato ; Linda M. Resar; George J Dover; David G Nichols; L Walker; James F Casella
Successful treatment of life-threatening acute chest syndrome of sickle cell disease with venovenous extracorporeal membrane oxygenation.
Journal of pediatric hematology/oncology 1997;19(5):459-61.
1996: Linda M. Resar; M M Oliva; James F Casella
Skull infarction and epidural hematomas in a patient with sickle cell anemia.
Journal of pediatric hematology/oncology 1996;18(4):413-5.
1995: Linda A Lee; Linda M. Resar; Chi Dang
Cell density and paradoxical transcriptional properties of c-Myc and Max in cultured mouse fibroblasts.
The Journal of clinical investigation 1995;95(2):900-4.
1993: Linda M. Resar; Christine E Dolde; J F Barrett; Chi Dang
B-myc inhibits neoplastic transformation and transcriptional activation by c-myc.
Molecular and cellular biology 1993;13(2):1130-6.
1993: Linda M. Resar; P C Phillips; M B Kastan; B G Leventhal; P W Bowman; Curt I Civin
Acute neurotoxicity after intrathecal cytosine arabinoside in two adolescents with acute lymphoblastic leukemia of B-cell type.
Cancer 1993;71(1):117-23.
1991: James J Potter; D Cheneval; Chi Dang; Linda M. Resar; Esteban Mezey; Yang Vincent
The upstream stimulatory factor binds to and activates the promoter of the rat class I alcohol dehydrogenase gene.
The Journal of biological chemistry 1991;266(23):15457-63.
1991: Linda M. Resar; F A Oski
Cold water exposure and vaso-occlusive crises in sickle cell anemia.
The Journal of pediatrics 1991;118(3):407-9.
1991: Chi Dang; J Barrett; M Villa-Garcia; Linda M. Resar; Gregory Kato ; Eric R Fearon
Intracellular leucine zipper interactions suggest c-Myc hetero-oligomerization.
Molecular and cellular biology 1991;11(2):954-62.