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Anna Friedl

Research Profile

Disorders

DNA Damage

Living Beings

Physiology

Chemicals & Drugs

Concepts & Ideas

Radiation Dose-Response Relationship

Phenomena

Anatomy

Hela Cells

Procedures

Pulsed Field Gel Electrophoresis

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Publications

TOP 3
Volker Hable; Judith Seel; Hilmar Strickfaden; Guido A Drexler; Anna Friedl; Christoph Greubel; Tino Brüning; Christian Burgdorf; Thomas Cremer; Anja Derer; G Dollinger
Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.
Guanghua Du; Anna Friedl; Werner Friedland; Christoph Greubel; Volker Hable; Reiner Krücken; Alexandra Kugler; Laura Tonelli; Guido A Drexler; G Dollinger
Spatial dynamics of DNA damage response protein foci along the ion trajectory of high-LET particles.
T E Schmid; G Dollinger; V Hable; C Greubel; Olga Zlobinskaya; D Michalski; S Auer; Anna Friedl; Ernst Schmid; Michael Molls; Barbara Röper
The effectiveness of 20 mev protons at nanosecond pulse lengths in producing chromosome aberrations in human-hamster hybrid cells.

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All Publications

2012: Volker Hable; Judith Seel; Hilmar Strickfaden; Guido A Drexler; Anna Friedl; Christoph Greubel; Tino Brüning; Christian Burgdorf; Thomas Cremer; Anja Derer; G Dollinger
Recruitment kinetics of DNA repair proteins Mdc1 and Rad52 but not 53BP1 depend on damage complexity.
PloS one 2012;7(7):e41943.
2011: Guanghua Du; Anna Friedl; Werner Friedland; Christoph Greubel; Volker Hable; Reiner Krücken; Alexandra Kugler; Laura Tonelli; Guido A Drexler; G Dollinger
Spatial dynamics of DNA damage response protein foci along the ion trajectory of high-LET particles.
Radiation research 2011;176(6):706-15.
2011: T E Schmid; G Dollinger; V Hable; C Greubel; Olga Zlobinskaya; D Michalski; S Auer; Anna Friedl; Ernst Schmid; Michael Molls; Barbara Röper
The effectiveness of 20 mev protons at nanosecond pulse lengths in producing chromosome aberrations in human-hamster hybrid cells.
Radiation research 2011;175(6):719-27.
2011: A Guertler; A Kraemer; U Roessler; S Hornhardt; U Kulka; S Moertl; Anna Friedl; T Illig; E Wichmann; M Gomolka
The WST survival assay: an easy and reliable method to screen radiation-sensitive individuals.
Radiation protection dosimetry 2011;143(2-4):487-90.
2011: Susanne Auer; Claus Belka; G Dollinger; Guido A Drexler; Christoph Greubel; Volker Hable; Thomas E Schmid; Anna Friedl
Survival of tumor cells after proton irradiation with ultra-high dose rates.
Radiation oncology (London, England) 2011;6():139.
2010: Anna Friedl; Markus Kiechle; Horst G Maxeiner; Robert H Schiestl; Friederike Eckardt-Schupp
Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae.
Molecular genetics and genomics : MGG 2010;284(4):231-42.
2010: Thomas E Schmid; G Dollinger; Wolfgang Beisker; Volker Hable; Christoph Greubel; Susanne Auer; Anja Mittag; Attila Tárnok; Anna Friedl; Michael Molls; Barbara Röper
Differences in the kinetics of gamma-H2AX fluorescence decay after exposure to low and high LET radiation.
International journal of radiation biology 2010;86(8):682-91.
2010: Anna Friedl; Werner Rühm
Editorial expression of concern regarding: Pilger A et al. (2004) No effects of intermittent 50 Hz EMF on cytoplasmic free calcium and on the mitochondrial membrane potential in human diploid fibroblasts, Radiat Environ Biophys 43:203-207.
Radiation and environmental biophysics 2010;49(3):293-4.
2010: Wouter W Wiegant; Matty Meyers; Nicole S Verkaik; Mirjam van der Burg; Firouz Darroudi; Ron J Romeijn; Ewa Bernatowska; Beata Wolska-Kusnierz; Bozena Mikoluc; Nicolaas G J Jaspers; Cees Vreeken; Hanna Ijspeert; Rebecca E E Esveldt-van Lange; Anna Friedl; Jean-Pierre De Villartay; Leon H F Mullenders; Jacques J M van Dongen; Dik C van Gent; Albert Pastink; Malgorzata Z Zdzienicka
A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity.
DNA repair 2010;9(4):365-73.
2010: Minglun Li; Anke Jung; Ute Ganswindt; Patrizia Marini; Anna Friedl; Peter T Daniel; Kirsten Lauber; Verena Jendrossek; Claus Belka
Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways.
Biochemical pharmacology 2010;79(2):122-9.
2009: T E Schmid; G Dollinger; A Hauptner; V Hable; C Greubel; S Auer; Anna Friedl; Michael Molls; Barbara Röper
No evidence for a different RBE between pulsed and continuous 20 MeV protons.
Radiation research 2009;172(5):567-74.
2008: Christoph Greubel; Volker Hable; Guido A Drexler; Andreas Hauptner; Steffen Dietzel; Hilmar Strickfaden; Iris Baur; Reiner Krücken; Thomas Cremer; Anna Friedl; Günther Dollinger
Quantitative analysis of DNA-damage response factors after sequential ion microirradiation.
Radiation and environmental biophysics 2008;47(4):415-22.
2008: Christoph Greubel; Volker Hable; Guido A Drexler; Andreas Hauptner; Steffen Dietzel; Hilmar Strickfaden; Iris Baur; Reiner Krücken; Thomas Cremer; Günther Dollinger; Anna Friedl
Competition effect in DNA damage response.
Radiation and environmental biophysics 2008;47(4):423-9.
2007: Firouz Darroudi; Wouter W Wiegant; Matty Meijers; Anna Friedl; Mirjam van der Burg; Janna Fomina; Jacques J M van Dongen; Dik C van Gent; Malgorzata Z Zdzienicka
Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle.
Mutation research 2007;615(1-2):111-24.
2006: Anna Friedl; Werner Rühm
LNT: a never-ending story.
Radiation and environmental biophysics 2006;44(4):241-4.
2006: A Hauptner; R Krücken; C Greubel; V Hable; G Dollinger; G A Drexler; M Deutsch; R Löwe; Anna Friedl; Steffen Dietzel; H Strickfaden; Thomas Cremer
DNA-repair protein distribution along the tracks of energetic ions.
Radiation protection dosimetry 2006;122(1-4):147-9.
2004: A Hauptner; Steffen Dietzel; G A Drexler; P Reichart; R Krücken; Thomas Cremer; Anna Friedl; G Dollinger
Microirradiation of cells with energetic heavy ions.
Radiation and environmental biophysics 2004;42(4):237-45.
2002: Markus Kiechle; Palaniyandi Manivasakam; Friederike Eckardt-Schupp; Robert H Schiestl; Anna Friedl
Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion.
Nucleic acids research 2002;30(24):e136.
2001: Anna Friedl; Batia Liefshitz; Rivka Steinlauf; Martin Kupiec
Deletion of the SRS2 gene suppresses elevated recombination and DNA damage sensitivity in rad5 and rad18 mutants of Saccharomyces cerevisiae.
Mutation research 2001;486(2):137-46.
2001: Anna Friedl; Albrecht M Kellerer
Comments on 'Underestimation of the small residual damage when measuring DNA double-strand breaks (DSB): is the repair of radiation-induced DSB complete?'.
International journal of radiation biology 2001;77(2):249-54.
2000: Markus Kiechle; Anna Friedl; Palaniyandi Manivasakam; Friederike Eckardt-Schupp; Robert H Schiestl
DNA integration by Ty integrase in yku70 mutant Saccharomyces cerevisiae cells.
Molecular and cellular biology 2000;20(23):8836-44.
2000: a Errami; Wilhelmina J I Overkamp; DM He; Anna Friedl; D A Gell; Friederike Eckardt-Schupp; SP Jackson; Eric A Hendrickson; Paul H M Lohman; Malgorzata Z Zdzienicka
A new X-ray sensitive CHO cell mutant of ionizing radiation group 7,XR-C2, that is defective in DSB repair but has only a mild defect in V(D)J recombination.
Mutation research 2000;461(1):59-69.
2000: Eberhard Fritz; Anna Friedl; R M Zwacka; Friederike Eckardt-Schupp; M Stephen Meyn
The yeast TEL1 gene partially substitutes for human ATM in suppressing hyperrecombination, radiation-induced apoptosis and telomere shortening in A-T cells.
Molecular biology of the cell 2000;11(8):2605-16.
2000: B Fellerhoff; Friederike Eckardt-Schupp; Anna Friedl
Subtelomeric repeat amplification is associated with growth at elevated temperature in yku70 mutants of Saccharomyces cerevisiae.
Genetics 2000;154(3):1039-51.
1999: Maria Kraakman-van der Zwet; Wilhelmina J I Overkamp; Anna Friedl; B Klein; G W Verhaegh; Nicolaas G J Jaspers; A T Midro; Friederike Eckardt-Schupp; Paul H M Lohman; Malgorzata Z Zdzienicka
Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts.
Mutation research 1999;434(1):17-27.
1998: F Kraxenberger; K J Weber; Anna Friedl; Friederike Eckardt-Schupp; M Flentje; P Quicken; Albrecht M Kellerer
DNA double-strand breaks in mammalian cells exposed to gamma-rays and very heavy ions. Fragment-size distributions determined by pulsed-field gel electrophoresis.
Radiation and environmental biophysics 1998;37(2):107-15.
1998: a Errami; DM He; Anna Friedl; Wilhelmina J I Overkamp; Bruno Morolli; Eric A Hendrickson; Friederike Eckardt-Schupp; M Oshimura; Paul H M Lohman; SP Jackson; Malgorzata Z Zdzienicka
XR-C1, a new CHO cell mutant which is defective in DNA-PKcs, is impaired in both V(D)J coding and signal joint formation.
Nucleic acids research 1998;26(13):3146-53.
1998: Batia Liefshitz; Rivka Steinlauf; Anna Friedl; F Eckardt-Schupp; Martin Kupiec
Genetic interactions between mutants of the 'error-prone' repair group of Saccharomyces cerevisiae and their effect on recombination and mutagenesis.
Mutation research 1998;407(2):135-45.
1998: Anna Friedl; Markus Kiechle; B Fellerhoff; Friederike Eckardt-Schupp
Radiation-induced chromosome aberrations in Saccharomyces cerevisiae: influence of DNA repair pathways.
Genetics 1998;148(3):975-88.
1996: Manfred Saran; U Hamm; Anna Friedl; Wolf Bors
Radiation-induced cell killing is highly dependent upon buffer treatment (filtration compared to autoclaving) due to metal-catalyzed formation of hypochlorite: a cautionary note.
Radiation research 1996;146(2):232-5.
1996: W Siede; Anna Friedl; I Dianova; Friederike Eckardt-Schupp; Errol C Friedberg
The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination.
Genetics 1996;142(1):91-102.
1995: Anna Friedl; A Kraxenberger; Friederike Eckardt-Schupp
An electrophoretic approach to the assessment of the spatial distribution of DNA double-strand breaks in mammalian cells.
Electrophoresis 1995;16(10):1865-74.
1994: A Kraxenberger; Anna Friedl; A M Kellerer
Computer simulation of pulsed field gel runs allows the quantitation of radiation-induced double-strand breaks in yeast.
Electrophoresis 1994;15(2):128-36.
1993: Anna Friedl; W Beisker; K Hahn; Friederike Eckardt-Schupp; Albrecht M Kellerer
Application of pulsed field gel electrophoresis to determine gamma-ray-induced double-strand breaks in yeast chromosomal molecules.
International journal of radiation biology 1993;63(2):173-81.
1992: T Wöhl; M Baur; Anna Friedl; Friedrich Lottspeich
Chromosomal localization of the HYP2-gene in Saccharomyces cerevisiae and use of pulsed-field gel electrophoresis for detection of irregular recombination events in gene disruption experiments.
Electrophoresis 1992;13(9-10):651-3.