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Stefan Schreiber

Research Profile

Genes & Molecular Sequences

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Germany

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Intestinal Mucosa

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Publications

TOP 3
Stefan Schreiber; Mandy Buch; Derek Holley; Edouard Louis; Julián Panés; Kristine Paridaens
National differences in ulcerative colitis experience and management among patients from five European countries and Canada: An online survey.
Arne S Schaefer; Ingmar Staufenbiel; Anneke Thien; Leonardo Trombelli; Cisca Wijmenga; Gregor Bochenek; Corinna Bruckmann; Naci Cine; Christof Doerfer; Jörg Eberhard; Peter Eickholz; Mathias Folwaczny; Christian Graetz; Esra Guzeldemir-Akcakanat; Inga Harks; Søren Jepsen; Yvonne Jockel-Schneider; Bruno G Loos; Thomas Manke; Joerg Meyle; Barbara Noack; Rahime Nohutcu; Michael Nothnagel; Chiara Scapoli; Stefan Schreiber
Validation of reported genetic risk factors for periodontitis in a large-scale replication study.
Rainer Noth; Philip Rosenstiel; Heiner Schäfer; Stefan Schreiber; Eckhard Stüber; Thilo Wedel; Burkhard Bewig; Martina Böttner; Mark Ellrichmann; Claudia Geismann; Jochen Hampe; Robert Häsler; Alexander Arlt
Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model.

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All Publications

2013: Stefan Schreiber; Mandy Buch; Derek Holley; Edouard Louis; Julián Panés; Kristine Paridaens
National differences in ulcerative colitis experience and management among patients from five European countries and Canada: An online survey.
Journal of Crohn's & colitis 2013;7(6):497-509.
2013: Arne S Schaefer; Ingmar Staufenbiel; Anneke Thien; Leonardo Trombelli; Cisca Wijmenga; Gregor Bochenek; Corinna Bruckmann; Naci Cine; Christof Doerfer; Jörg Eberhard; Peter Eickholz; Mathias Folwaczny; Christian Graetz; Esra Guzeldemir-Akcakanat; Inga Harks; Søren Jepsen; Yvonne Jockel-Schneider; Bruno G Loos; Thomas Manke; Joerg Meyle; Barbara Noack; Rahime Nohutcu; Michael Nothnagel; Chiara Scapoli; Stefan Schreiber
Validation of reported genetic risk factors for periodontitis in a large-scale replication study.
Journal of clinical periodontology 2013;40(6):563-72.
2013: Rainer Noth; Philip Rosenstiel; Heiner Schäfer; Stefan Schreiber; Eckhard Stüber; Thilo Wedel; Burkhard Bewig; Martina Böttner; Mark Ellrichmann; Claudia Geismann; Jochen Hampe; Robert Häsler; Alexander Arlt
Oral glutamine supplementation improves intestinal permeability dysfunction in a murine acute graft-vs.-host disease model.
American journal of physiology. Gastrointestinal and liver physiology 2013;304(7):G646-54.
2013: Christian Jürgensen; Frank Neser; Michael Nothnagel; Stefan Schreiber; Ulrich Stölzel; Martin Zeitz; Alexander Arlt; Jana Brand; Jörg-Olaf Habeck; Jochen Hampe
Prognostic relevance of gastric cancer staging by endoscopic ultrasound.
Surgical endoscopy 2013;27(4):1124-9.
2013: Sylvia Hofmann; Kerstin Höhne; Gunnar Jacobs; Frantisek Mrazek; Joachim Müller-Quernheim; Michael Nothnagel; Stefan Pabst; Martin Petrek; Marcus Ronninger; Philip Rosenstiel; Benjamin Schmid; Anders Eklund; Annegret Fischer; Andre Franke; Karoline I Gaede; Christian Grohé; Johan Grunewald; Manfred Schürmann; Michael Wittig; Gernot Zissel; Stefan Schreiber
Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2013;41(4):888-900.
2013: Stefan Schreiber; W Reinisch; A M Robinson; William J Sandborn; Jean-Frédéric Colombel; D W Hommes; B Huang; K G Lomax; Paul F Pollack
Subgroup analysis of the placebo-controlled CHARM trial: increased remission rates through 3 years for adalimumab-treated patients with early Crohn's disease.
Journal of Crohn's & colitis 2013;7(3):213-21.
2013: Christian Sina; Andreas Till; Paul Saftig; Stefan Schreiber; Konrad Aden; Olga Gavrilova; Robert Haesler; Simone Lipinski; Michael A McGuckin; Ulf Meyer-Hoffert; Emilie Midtling; Rainer Podschun; Katrin Pütsep; Ateequr Rehman; Andrea Rittger; Philip Rosenstiel
Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice.
Gut 2013;62(4):520-30.
2013: A Auinger; F Döring; Ulrich R Foelsch; Ulf Helwig; Diana Rubin; A Rüther; M Sabandal; Stefan Schreiber; Jürgen Schrezenmeir
A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome.
The British journal of nutrition 2013;109(5):810-5.
2013: Witigo von Schönfels; Maren Wölk; Stefan Schreiber; Heiko Aselmann; Thomas Becker; Stephan Buch; Jan H Egberts; Jochen Hampe; Michael Krawczak; Clemens Schafmayer
Recurrence of gallstones after cholecystectomy is associated with ABCG5/8 genotype.
Journal of gastroenterology 2013;48(3):391-6.
2013: Stefanie Derer; Nils Grabe; Joachim Groetzinger; Robert Haesler; Sascha Jung; Tanja Kuehbacher; Susanna Nikolaus; Stefan Rose-John; Philip Rosenstiel; Christian Sina; Andreas Till; Stefan Schreiber
mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.
Gut 2013;62(3):376-86.
2013: S Nikolaus; Stefan Schreiber
[Treatment of inflammatory bowel disease].
Deutsche medizinische Wochenschrift (1946) 2013;138(5):205-8.
2013: Jesús Lascorz; Clemens Schafmayer; Stefan Schreiber; Witigo V Schönfels; Heiko Aselmann; Thomas Becker; Jan Beckmann; Melanie Bevier; Stephan Buch; Jan Egberts; Jochen Hampe; Kari Hemminki; Holger Kalthoff; Asta Försti
Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer.
International journal of colorectal disease 2013;28(2):173-81.
2013: Friederike Flachsbart; Liljana Gentschew; Rabea Kleindorp; Michael Krawczak; Michael Möller; Almuth Caliebe; Carolin Däumer; Stefan Schreiber; Almut Nebel
Genetic investigation of FOXO3A requires special attention due to sequence homology with FOXO3B.
European journal of human genetics : EJHG 2013;21(2):240-2.
2013: Michael Forster; Peter Forster; Matthias Barann; David Ellinghaus; Abdou ElSharawy; Georg Hemmrich; Andreas Keller; Benjamin Kreck; Sandra May; Espen Melum; Britt-Sabina Petersen; Philip Rosenstiel; Markus Schilhabel; Stefan Schreiber; Björn Stade; Ingo Thomsen; Michael Wittig; Andre Franke
From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software.
Nucleic acids research 2013;41(1):e16.
2013: Luc Biedermann; Anja Frei; Pascal Frei; Michael Fried; Martin J Loessner; Jessica Mwinyi; Stephan J Ott; Ateequr Rehman; Michael Scharl; Stefan Schreiber; Markus Schuppler; Claudia Steurer-Stey; Eveline Sutter-Minder; Stephan R Vavricka; Jonas Zeitz; Gerhard Rogler
Smoking cessation induces profound changes in the composition of the intestinal microbiota in humans.
PloS one 2013;8(3):e59260.
2012: Simone Lipinski; Maren Paulsen; Stefan Schreiber; Andreas Till; Konrad Aden; Alexander Arlt; Susanne Billmann-Born; Kai Sven Erdmann; Nils Grabe; Nina Hagemann; Robert Häsler; Gunnar Jacobs; Lars Kraemer; Philip Rosenstiel
RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):21426-31.
2012: Caspar Grond-Ginsbach; Ingrid Hausser; Kari Hemminki; Yanxiang Jiang; Manja Kloss; Michael Krawczak; Christoph Lichy; Philippe A Lyrer; Rastislav Pjontek; Stefan Schreiber; Sandrine Tchatchou; Tina Wiest; Marie-Luise Arnold; Tobias Brandt; Barbara Burwinkel; Bowang Chen; Stefan Engelter
Copy number variation in patients with cervical artery dissection.
European journal of human genetics : EJHG 2012;20(12):1295-9.
2012: Claudia Fritsch; Jochen Hampe; Alexander Herrmann; Klaus Huse; Michael Krawczak; Michael Nothnagel; Matthias Platzer; Stefan Schreiber; Frank Schumann; Karol Szafranski; Mario Brosch
Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting.
Genome research 2012;22(11):2208-18.
2012: Annegret Fischer; Andre Franke; Karoline I Gaede; Christian Gieger; Christian Grohé; Johan Grunewald; Sylvia Hofmann; Kerstin Höhne; Vitezslav Kolek; Simone Lipinski; Joachim Müller-Quernheim; Almut Nebel; Michael Nothnagel; Stefan Pabst; Leonid Padyukov; Martin Petrek; Marcus Ronninger; Philip Rosenstiel; Benjamin Schmid; Anders Eklund; David Ellinghaus; Manfred Schürmann; H-Erich Wichmann; Gernot Zissel; Stefan Schreiber
A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.
American journal of respiratory and critical care medicine 2012;186(9):877-85.
2012: Robert Häsler; Vardhman K Rakyan; Liselotte Bäckdahl; Stephan Beck; Thomas A Down; Andrew Feber; Zhe Feng; Andre Franke; Stefan Schreiber; Martina E Spehlmann; Andrew E Teschendorff; Gareth A Wilson; Philip Rosenstiel
A functional methylome map of ulcerative colitis.
Genome research 2012;22(11):2130-7.
2012: Lukas Windhager; Ralf Zimmer; Thomas Bonfert; Kaspar Burger; Dirk Eick; Caroline C Friedel; Stefanie Kaufmann; Stefan Krebs; Anne L'Hernault; Georg Malterer; Philip Rosenstiel; Zsolt Ruzsics; Markus Schilhabel; Stefan Schreiber; Lars Dölken
Ultrashort and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution.
Genome research 2012;22(10):2031-42.
2012: Silke Appenzeller; Daniela Berg; Günther Deuschl; Thomas Gasser; Johann Hagenah; Meike Kasten; Christine Klein; Frank Papengut; Stefan Schreiber; Karin Srulijes; Sandra Thier; Gregor Kuhlenbäumer
No association between NOD2 variants and Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(9):1191-2.
2012: Esther J Lee; Cheryl Makarewicz; Johannes Müller; Stephanie Müller; Sven Ostritz; Rebecca Renneberg; Stefan Schreiber; Nicole von Wurmb-Schwark; Lars Fehren-Schmitz; Melanie Harder; Ben Krause-Kyora; Almut Nebel
Emerging genetic patterns of the European Neolithic: perspectives from a late Neolithic Bell Beaker burial site in Germany.
American journal of physical anthropology 2012;148(4):571-9.
2012: Abdou ElSharawy; Friederike Flachsbart; Andre Franke; Gunnar Jacobs; Nathalie Kefer; Andreas Keller; Petra Leidinger; Eckart Meese; Christina Backes; Thomas Brefort; Philip Rosenstiel; Stefan Schreiber; Anke Wendschlag; Almut Nebel
Genome-wide miRNA signatures of human longevity.
Aging cell 2012;11(4):607-16.
2012: Sebastian Zeissig; Alexander Arlt; Katharina Balschun; Jody L Baron; Esther Bosse; Rainer Günther; Jochen Hampe; Zongyi Hu; M Mahmood Hussain; Jahangir Iqbal; Arthur Kaser; T Jake Liang; D Branch Moody; Kazumoto Murata; Jean Publicover; Christoph Röcken; Stefan Schreiber; Lindsay Sweet; Richard S Blumberg
Hepatitis B virus-induced lipid alterations contribute to natural killer T cell-dependent protective immunity.
Nature medicine 2012;18(7):1060-8.
2012: William J Sandborn; Bruce E Sands; Stefan Schreiber; Stephan R Targan; Richard Aranda; Brian Bressler; Jean-Frederic Colombel; Karl Geboes; Sheila Gujrathi; Allison Luo; Remo Panaccione; Yun Peng; Paul Rutgeerts; Luisa Salter-Cid; Stephen B Hanauer
Abatacept for Crohn's disease and ulcerative colitis.
Gastroenterology 2012;143(1):62-69.e4.
2012: Diana Rubin; Andreas Ruether; Stefan Schreiber; Annegret Auinger; Stephanie Darabaneanu; Sandra Freitag-Wolf; Ulf Helwig; Dennis Matusch; Michael Nothnagel; Maria Pfeuffer; Jürgen Schrezenmeir
The effect of FABP2 promoter haplotype on response to a diet with medium-chain triacylglycerols.
Genes & nutrition 2012;7(3):437-45.
2012: Rainer Noth; Stefan Schreiber; Eckhard Stüber; Burkhard Bewig; Jochen Hampe; Robert Häsler; Tanja Kühbacher; Susanna Nikolaus; Alexander Arlt
Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease.
Journal of Crohn's & colitis 2012;6(4):464-9.
2012: E Ellinghaus; Abdou ElSharawy; C Franceschi; T Bartram; Gunnar Cario; H Cavé; Giovanni Cazzaniga; Ondrej Cinek; D Ellinghaus; M Giordan; Robert Häsler; B Heinzow; M Horstmann; Francesco Lescai; Barbara Meissner; Almut Nebel; Peter Nürnberg; R Panzer Grümayer; G Richter; Martin Schrappe; Stefan Schreiber; Martin Stanulla; Geertruy Te Kronnie; Andrea Teigler-Schlegel; Jan Trka; Martin Zimmermann; Andre Franke
Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Leukemia 2012;26(5):902-9.
2012: Annegret Auinger; Nour Eddine El Mokhtari; Ulrich R Fölsch; Norbert Frey; Ulf Helwig; Mark Luedde; Maria Pfeuffer; Tim Rausche; Diana Rubin; Stefan Schreiber; Jürgen Schrezenmeir
A variant in the heart-specific fatty acid transport protein 6 is associated with lower fasting and postprandial TAG, blood pressure and left ventricular hypertrophy.
The British journal of nutrition 2012;107(10):1422-8.
2012: David Ellinghaus; Eva Ellinghaus; Tõnu Esko; Gonçalo R Abecasis; Vito Annese; Tobias Balschun; Jonathan N Barker; Majid Belouchi; Sophie Debrus; James T Elder; Christian Gieger; Michael Kabesch; Külli Kingo; Sulev Kõks; Christopher G Mathew; Andres Metspalu; Rajan P Nair; Susanna Nikolaus; Michael Nothnagel; Orazio Palmieri; John V Raelson; Stefan Schreiber; Philip E Stuart; Trilokraj Tejasvi; Richard C Trembath; Michael Weichenthal; Stephan Weidinger; Sarah L West; H-Erich Wichmann; Andre Franke
Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci.
American journal of human genetics 2012;90(4):636-47.
2012: Gesa M Richter; Stefan Schreiber; Henrik Dommisch; Peter Eickholz; Mathias Folwaczny; Christian Graetz; Birte Groessner-Schreiber; Søren Jepsen; Marja L Laine; Bruno G Loos; Barbara Noack; Michael Nothnagel; Pia Pohler; Arne S Schaefer
Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations.
Journal of clinical periodontology 2012;39(4):315-22.
2012: Eva Ellinghaus; Tonu Esko; Gonçalo R Abecasis; Majid Belouchi; Anne M Bowcock; Sophie Debrus; James T Elder; David Ellinghaus; Christian Gieger; Dafna D Gladman; Cynthia Helms; Külli Kingo; Sulev Koks; Gerald G Krueger; Yanming Li; Andres Metspalu; Ulrich Mrowietz; Rajan P Nair; Anna T Onken; John V Raelson; Proton Rahman; Stefan Schreiber; Philip Stuart; Trilokraj Tejasvi; Lam C Tsoi; Michael Weichenthal; Stephan Weidinger; H-Erich Wichmann; Andre Franke
Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL.
The Journal of investigative dermatology 2012;132(4):1133-40.
2012: Ole Ammerpohl; Alexander Arlt; Katharina Balschun; Thomas Becker; Mario Brosch; Wladimir Faber; Jonas Grauholm; Andrea Haake; Holger Kalthoff; Peter Neuhaus; Johann Pratschke; Christoph Röcken; Clemens Schafmayer; Bodo Schniewind; Stefan Schreiber; Reiner Siebert; Bence Sipos; Felix Stickel; Oliver von Kampen; Witigo von Schönfels; Jochen Hampe
Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2012;130(6):1319-28.
2012: Mario Brosch; Marcus Ahrens; Thomas Becker; Michael Krawczak; Matthias Laudes; Michael Nothnagel; Christoph Röcken; Clemens Schafmayer; Stefan Schreiber; Bence Sipos; Witigo von Schönfels; Jochen Hampe
SFRS10--a splicing factor gene reduced in human obesity?
Cell metabolism 2012;15(3):265-6; author reply 267-9.
2012: Remo Panaccione; Laurent Peyrin-Biroulet; Toshifumi Hibi; Stefan Schreiber
Implementing changes in clinical practice to improve the management of Crohn's disease.
Journal of Crohn's & colitis 2012;6 Suppl 2():S235-42.
2012: Martina E Spehlmann; Ute Tiemann; Alexander Z Begun; Frank Hinrichs; Andreas Raedler; Ekaterini Saroglou; Stefan Schreiber
Risk factors in German twins with inflammatory bowel disease: results of a questionnaire-based survey.
Journal of Crohn's & colitis 2012;6(1):29-42.
2012: Eva E R Philipp; Gerald Rimbach; Doris Abele; Insa M A Ernst; Heike Gruber; Lars Kraemer; Stefan Schreiber; Julia Strahl; Anika E Wagner; Wiebke Wessels; Philip Rosenstiel
Gene expression and physiological changes of different populations of the long-lived bivalve Arctica islandica under low oxygen conditions.
PloS one 2012;7(9):e44621.
2012: Abdou ElSharawy; Michael Forster; James Brayer; Darren R Link; Jeff Olson; Stefan Rose-John; Philip Rosenstiel; Markus Schilhabel; Stefan Schreiber; Jason Warner; Andre Franke
Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing.
BMC genomics 2012;13():500.
2012: Abdou ElSharawy; Michael Forster; Andreas Keller; Britt-Sabina Petersen; Philip Rosenstiel; Nadine Schracke; Stefan Schreiber; Björn Stade; Peer Stähler; Ingo Thomsen; Andre Franke
Improving mapping and SNP-calling performance in multiplexed targeted next-generation sequencing.
BMC genomics 2012;13():417.
2012: Stefan Schreiber; Mandy Buch; Derek Holley; Edouard Louis; Julián Panés; Kristine Paridaens
Perception gaps between patients with ulcerative colitis and healthcare professionals: an online survey.
BMC gastroenterology 2012;12():108.
2012: Jesús Lascorz; Witigo V Schönfels; Stefan Schreiber; Heiko Aselmann; Thomas Becker; Jan Beckmann; Melanie Bevier; Stephan Buch; Jan Egberts; Asta Försti; Jochen Hampe; Kari Hemminki; Holger Kalthoff; Clemens Schafmayer
Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer.
BMC medical genetics 2012;13():31.
2012: Ateequr Rehman; Stefan Schreiber; Koen Venema; Femke-Anouska Heinsen; Stephan Hellmig; Henrik Knecht; Marjorie E Koenen; Stephan J Ott
Effects of probiotics and antibiotics on the intestinal homeostasis in a computer controlled model of the large intestine.
BMC microbiology 2012;12():47.
2012: Eva E R Philipp; Albert J Poustka; Ulrike Findeisen; Lars Kraemer; Frank Melzner; Stefan Schreiber; Sebastian Thieme; Philip Rosenstiel
Massively parallel RNA sequencing identifies a complex immune gene repertoire in the lophotrochozoan Mytilus edulis.
PloS one 2012;7(3):e33091.
2012: Katherine L Helbig; Susanna Nikolaus; Tobias Balschun; Andre Franke; Jochen Hampe; Michael Nothnagel; Stefan Schreiber; Ute Nöthlings
A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology.
BMC medical genetics 2012;13():14.
2012: Robert Häsler; Gunnar Jacobs; kaiqin lao; Susanna Nikolaus; Christian Cordes; Nils Grabe; Stefan Schreiber; Andreas Till; Philip Rosenstiel
Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes.
PloS one 2012;7(2):e31151.
2011: Philipp Rausch; Ateequr Rehman; Philip Rosenstiel; Stefan Schreiber; Andre Franke; Robert Häsler; Sven Künzel; Stephan J Ott; John F Baines
Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(47):19030-5.
2011: Stefan Schreiber
Certolizumab pegol for the treatment of Crohn's disease.
Therapeutic advances in gastroenterology 2011;4(6):375-89.
2011: Friederike Flachsbart; Rabea Kleindorp; Susanna Nikolaus; Stefan Schreiber; Mike Ufer; Almut Nebel
Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population.
The journals of gerontology. Series A, Biological sciences and medical sciences 2011;66(11):1186-91.
2011: Eun-Kyung Suk; Jorge Duitama; Dustin T Holloway; Thomas Huebsch; Clarence Lee; Gayle K McEwen; Stephen McLaughlin; Katja Nowick; Stefanie Palczewski; Heather Peckham; Stefan Schreiber; Sabrina Schulz; Margret R Hoehe
A comprehensively molecular haplotype-resolved genome of a European individual.
Genome research 2011;21(10):1672-85.
2011: Ateequr Rehman; Stefan Schreiber; Christian Sina; John F Baines; Olga Gavrilova; Robert Häsler; Stephan Ott; Philip Rosenstiel
Nod2 is essential for temporal development of intestinal microbial communities.
Gut 2011;60(10):1354-62.
2011: Michael Nothnagel; Matthias Platzer; Stefan Schreiber; Reiner Siebert; Andreas Wolf; Alexander Herrmann; Michael Krawczak; Jochen Hampe
Technology-specific error signatures in the 1000 Genomes Project data.
Human genetics 2011;130(4):505-16.
2011: Stephan J Ott; Stefan Schreiber
[Genetic susceptibility to infections].
Der Internist 2011;52(9):1053-4, 1056-8, 1060.
2011: Patricia Huebbe; Jennifer Moehring; Erika Most; Manfred James Müller; Almut Nebel; Ute Nöthlings; Josef Pallauf; Christine Boesch-Saadatmandi; Sarah Egert; Stefan Schreiber; Sabine Siegert; Gerald Rimbach
APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011;25(9):3262-70.
2011: S Thier; K Christensen; Günther Deuschl; Gregor Kuhlenbäumer; Delia Lorenz; Almut Nebel; Michael Nothnagel; Stefan Schreiber; Stephan Klebe
GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2011;18(8):1098-100.
2011: William J Sandborn; Stefan Schreiber; Ziad H Younes; Ralph Bloomfield; Geoffroy Coteur; Brian G Feagan; Juan Pablo Guzman; Paul Rutgeerts; Geert R D'Haens
Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2011;9(8):670-678.e3.
2011: Rabea Kleindorp; Alberto Malovini; Annibale A Puca; Stefan Schreiber; Friederike Flachsbart; Almut Nebel
Candidate gene study of FOXO1, FOXO4, and FOXO6 reveals no association with human longevity in Germans.
Aging cell 2011;10(4):622-8.
2011: Patricia Lepage; Stephan Ott; Andreas Raedler; Ateequr Rehman; Alexander Begun; Joël Doré; Robert Häsler; Limas Kupcinskas; Martina E Spehlmann; Aida Zvirbliene; Stefan Schreiber
Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis.
Gastroenterology 2011;141(1):227-36.
2011: Christian Cordes; Robert Häsler; Christian Werner; Tibor Görögh; Christoph Röcken; Lena Hebebrand; W Martin Kast; Markus Hoffmann; Stefan Schreiber; Petra Ambrosch
The level of secretory leukocyte protease inhibitor is decreased in metastatic head and neck squamous cell carcinoma.
International journal of oncology 2011;39(1):185-91.
2011: Gunnar Jacobs; Wolfram Klapper; Markus Kosmahl; Ruta Kwiatkowski; Ralph Lucius; Stephan Ott; Wolfgang Fischbach; Ulrich R Fölsch; Andre Franke; Jochen Hampe; Stephan Hellmig; Klaus Huse; Stefan Schreiber; Andrea Titz; Philip Rosenstiel
Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma.
Haematologica 2011;96(7):987-95.
2011: Delia Lorenz; F Papengut; C Poremba; Stefan Schreiber; Günther Deuschl
The psychosocial burden of essential tremor in an outpatient- and a community-based cohort.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2011;18(7):972-9.
2011: Almut Nebel; Susanna Nikolaus; Michael Nothnagel; Heinz-Erich Wichmann; Michael Wittig; Hélène Blanché; Amke Caliebe; David Ellinghaus; Friederike Flachsbart; Andre Franke; Olaf Junge; Rabea Kleindorp; Michael Krawczak; Mark Lathrop; Thomas Meitinger; Stefan Schreiber
A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.
Mechanisms of ageing and development 2011;132(6-7):324-30.
2011: Lindsey A Adams; Marlo Möller; Almut Nebel; Stefan Schreiber; Lize van der Merwe; Paul D van Helden; Eileen G Hoal
Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.
European journal of human genetics : EJHG 2011;19(6):676-81.
2011: Robert Häsler; Martin Kerick; Nancy Mah; Claus Hultschig; Gesa Richter; Frank Bretz; Christian Sina; Hans Lehrach; Wilfried Nietfeld; Stefan Schreiber; Philip Rosenstiel
Alterations of pre-mRNA splicing in human inflammatory bowel disease.
European journal of cell biology 2011;90(6-7):603-11.
2011: Susanne Billmann-Born; Simone Lipinski; Janne Böck; Andreas Till; Philip Rosenstiel; Stefan Schreiber
The complex interplay of NOD-like receptors and the autophagy machinery in the pathophysiology of Crohn disease.
European journal of cell biology 2011;90(6-7):593-602.
2011: Felipe Andres Castro; Asta Försti; S Buch; H Kalthoff; C Krauss; M Bauer; J Egberts; B Schniewind; D C Broering; Stefan Schreiber; M Schmitt; J Hampe; Kari Hemminki; Clemens Schafmayer
TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer.
European journal of cancer (Oxford, England : 1990) 2011;47(8):1203-10.
2011: Susanne Billmann-Born; Andreas Till; Alexander Arlt; Simone Lipinski; Christian Sina; Anna Latiano; Vito Annese; Robert Häsler; Martin Kerick; Thomas Manke; Dirk Seegert; Adedayo Hanidu; Heiner Schäfer; David van Heel; Jun Li; Stefan Schreiber; Philip Rosenstiel
Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(7):4027-38.
2011: Rene Pahl; Gabriele Brunke; Nadine Steubesand; Sabine Schubert; Martina Böttner; Thilo Wedel; Christian Jürgensen; Jochen Hampe; Heiner Schäfer; Sebastian Zeissig; Stefan Schreiber; Philip Rosenstiel; Karina Reiss; Alexander Arlt
IL-1β and ADAM17 are central regulators of β-defensin expression in Candida esophagitis.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(4):G547-53.
2011: Anja Freiwald; Lei Mao; Vitam Kodelja; Magdalena Kliem; Dörthe Schuldt; Stefan Schreiber; Andre Franke; Sascha Sauer
Differential analysis of Crohn's disease and ulcerative colitis by mass spectrometry.
Inflammatory bowel diseases 2011;17(4):1051-2.
2011: Marcel Kramer; Klaus Huse; Uwe Menzel; Oliver Backhaus; Philip Rosenstiel; Stefan Schreiber; Jochen Hampe; Matthias Platzer
Constant splice-isoform ratios in human lymphoblastoid cells support the concept of a splico-stat.
Genetics 2011;187(3):761-70.
2011: A Fischer; Michael Nothnagel; Andre Franke; G Jacobs; H R Saadati; K I Gaede; Philip Rosenstiel; Manfred Schürmann; Joachim Müller-Quernheim; Stefan Schreiber; S Hofmann
Association of inflammatory bowel disease risk loci with sarcoidosis, and its acute and chronic subphenotypes.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;37(3):610-6.
2011: Rainer Noth; Philip Rosenstiel; Stefan Schreiber; Eckhard Stüber; Burkhard Bewig; Mark Ellrichmann; Jochen Hampe; Robert Häsler; Marie-Luise Kruse; Julia Lange-Grumfeld; Alexander Arlt
Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model.
BMC gastroenterology 2011;11():109.
2011: Alexander Herrmann; Steve K Kotsopoulos; Michael Krawczak; Darren R Link; Idoia Martin-Guerrero; Michael Nothnagel; Peter Nürnberg; Jeff Olson; Matthias Platzer; Julia Richter; Stefan Schreiber; Reiner Siebert; Kathryn Stemshorn; Karol Szafranski; Jason Warner; Ole Ammerpohl; Andrea Haake; Jochen Hampe
Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors.
PloS one 2011;6(7):e21332.
2011: Ulrich C Klostermeier; Benjamin Kreck; Matthias Barann; Andre Franke; Olga Gavrilova; Robert Häsler; Markus Schilhabel; Stefan Schreiber; Christian Sina; Michael Wittig; Philip Rosenstiel
A tissue-specific landscape of sense/antisense transcription in the mouse intestine.
BMC genomics 2011;12():305.
2011: Stefan Taudien; Xinmin Zhang; Marius Felder; Marco Groth; Jochen Hampe; Klaus Huse; Andreas Petzold; Francesca Raffaelli; Philip Rosenstiel; Stefan Schreiber; Karol Szafranski; Matthias Platzer
Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing.
BMC genomics 2011;12(1):243.
2011: F Rieder; Rocio Lopez; Andre Franke; Alexandra Wolf; Stephan Schleder; Andrea Dirmeier; Anja Schirbel; Philip Rosenstiel; Nir Dotan; Stefan Schreiber; Gerhard Rogler; Frank Klebl
Characterization of changes in serum anti-glycan antibodies in Crohn's disease--a longitudinal analysis.
PloS one 2011;6(5):e18172.
2011: Arne S Schaefer; Gesa M Richter; Henrik Dommisch; Markus Reinartz; Michael Nothnagel; Barbara Noack; Marja L Laine; Mathias Folwaczny; Birte Groessner-Schreiber; Bruno G Loos; Søren Jepsen; Stefan Schreiber
CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection.
Journal of medical genetics 2011;48(1):38-47.
2011: William J Sandborn; Jean-Frédéric Colombel; Stefan Schreiber; Scott Plevy; Paul F Pollack; Anne M Robinson; Jingdong Chao; Parvez Mulani
Dosage adjustment during long-term adalimumab treatment for Crohn's disease: clinical efficacy and pharmacoeconomics.
Inflammatory bowel diseases 2011;17(1):141-51.
2010: Friederike Flachsbart; Andre Franke; Rabea Kleindorp; Almuth Caliebe; Hélène Blanché; Stefan Schreiber; Almut Nebel
Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.
Mutation research 2010;694(1-2):13-9.
2010: Stephan Buch; Clemens Schafmayer; Henry Völzke; Markus Seeger; Juan Miquel; Silvia C Sookoian; Jan-Hendrik Egberts; Alexander Arlt; Carlos J Pirola; Markus M Lerch; Ulrich John; Andre Franke; Oliver von Kampen; Mario Brosch; Michael Nothnagel; Wolfgang Kratzer; Bernhard O Boehm; Dieter C Bröring; Stefan Schreiber; Michael Krawczak; Jochen Hampe
Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition.
Gastroenterology 2010;139(6):1942-1951.e2.
2010: Marcus Seeger; Rainer Günther; Holger Hinrichsen; Marcus Both; Ulf Helwig; Alexander Arlt; Birte Stelck; Jan H Bräsen; Bence Sipos; Clemens Schafmayer; Felix Braun; Dieter C Bröring; Stefan Schreiber; Jochen Hampe
Chronic portal vein thrombosis: transcapsular hepatic collateral vessels and communicating ectopic varices.
Radiology 2010;257(2):568-78.
2010: Michael Wittig; Ingo Helbig; Stefan Schreiber; Andre Franke
CNVineta: a data mining tool for large case-control copy number variation datasets.
Bioinformatics (Oxford, England) 2010;26(17):2208-9.
2010: Sarah von Spiczak; Hiltrud Muhle; Ingo Helbig; Carolien G F de Kovel; Jochen Hampe; Verena Gaus; Bobby P C Koeleman; Dick Lindhout; Stefan Schreiber; Thomas Sander; Ulrich Stephani
Association study of TRPC4 as a candidate gene for generalized epilepsy with photosensitivity.
Neuromolecular medicine 2010;12(3):292-9.
2010: Ateequr Rehman; Patricia Lepage; Andreas Nolte; Stephan Hellmig; Stefan Schreiber; Stephan J Ott
Transcriptional activity of the dominant gut mucosal microbiota in chronic inflammatory bowel disease patients.
Journal of medical microbiology 2010;59(Pt 9):1114-22.
2010: Stephan Klebe; Sandra Thier; Delia Lorenz; Michael Nothnagel; Stefan Schreiber; Christine Klein; Johann Hagenah; Meike Kasten; Daniela Berg; Karin Srulijes; Thomas Gasser; Günther Deuschl; Gregor Kuhlenbäumer
LINGO1 is not associated with Parkinson's disease in German patients.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(6):1173-8.
2010: M Groth; C Wiegand; Karol Szafranski; Klaus Huse; M Kramer; Philip Rosenstiel; Stefan Schreiber; J Norgauer; Matthias Platzer
Both copy number and sequence variations affect expression of human DEFB4.
Genes and immunity 2010;11(6):458-66.
2010: Andrew P A Oxley; Mariana P Lanfranconi; Dieco Würdemann; Stephan Ott; Stefan Schreiber; Terry J McGenity; Kenneth N Timmis; Balbina Nogales
Halophilic archaea in the human intestinal mucosa.
Environmental microbiology 2010;12(9):2398-410.
2010: Athena Chalaris; Nina Adam; Christian Sina; Philip Rosenstiel; Judith Lehmann-Koch; Peter Schirmacher; Dieter Hartmann; Joanna Cichy; Olga Gavrilova; Stefan Schreiber; Thomas Jostock; Vance Matthews; Robert Häsler; Christoph Becker; Markus F Neurath; Karina Reiss; Paul Saftig; Jürgen Scheller; Stefan Rose-John
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
The Journal of experimental medicine 2010;207(8):1617-24.
2010: Espen Melum; Sandra May; Markus B Schilhabel; Ingo Thomsen; Tom H Karlsen; Philip Rosenstiel; Stefan Schreiber; Andre Franke
SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region.
Human mutation 2010;31(7):875-85.
2010: Almuth Caliebe; Rabea Kleindorp; Hélène Blanché; Lene Christiansen; Annibale Alessandro Puca; I Maeve or Maeve Rea; Eline Slagboom; Friederike Flachsbart; Kaare Christensen; Gerald Rimbach; Stefan Schreiber; Almut Nebel
No or only population-specific effect of PON1 on human longevity: a comprehensive meta-analysis.
Ageing research reviews 2010;9(3):238-44.
2010: Stefan Schreiber; Jean-Frédéric Colombel; Ralph Bloomfield; Susanna Nikolaus; Jürgen Schölmerich; Julian Panés; William J Sandborn
Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data.
The American journal of gastroenterology 2010;105(7):1574-82.
2010: Oliver von Kampen; Simone Lipinski; Andreas Till; Seamus J Martin; Wilfried Nietfeld; Hans Lehrach; Stefan Schreiber; Philip Rosenstiel
Caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling.
The Journal of biological chemistry 2010;285(26):19921-6.
2010: Andreas Fiebig; Petra Krusche; Andreas Wolf; Michael Krawczak; Birgitt Timm; Susanna Nikolaus; Norbert Frings; Stefan Schreiber
Heritability of chronic venous disease.
Human genetics 2010;127(6):669-74.
2010: Brian G Feagan; M C Reilly; L Gerlier; Y Brabant; M Brown; Stefan Schreiber
Clinical trial: the effects of certolizumab pegol therapy on work productivity in patients with moderate-to-severe Crohn's disease in the PRECiSE 2 study.
Alimentary pharmacology & therapeutics 2010;31(12):1276-85.
2010: Hiltrud Muhle; Sarah von Spiczak; Verena Gaus; Serife Kara; Ingo Helbig; Jochen Hampe; Andre Franke; Yvonne Weber; Holger Lerche; Ailing A Kleefuss-Lie; Christian E Elger; Stefan Schreiber; Ulrich Stephani; Thomas Sander
Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis.
Epilepsy research 2010;89(2-3):319-26.
2010: Marcel Kramer; Oliver Backhaus; Philip Rosenstiel; Denise Horn; Eva Klopocki; Gerd Birkenmeier; Stefan Schreiber; Matthias Platzer; Jochen Hampe; Klaus Huse
Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing.
Gene 2010;455(1-2):1-7.
2010: Sandra Thier; Delia Lorenz; Michael Nothnagel; Giovanni Stevanin; Alexandra Dürr; Almut Nebel; Stefan Schreiber; Gregor Kuhlenbäumer; Günther Deuschl; Stephan Klebe
LINGO1 polymorphisms are associated with essential tremor in Europeans.
Movement disorders : official journal of the Movement Disorder Society 2010;25(6):717-23.
2010: Andre Franke; Tobias Balschun; Christian Sina; David Ellinghaus; Robert Häsler; Gabriele Mayr; Mario Albrecht; Michael Wittig; Eva Buchert; Susanna Nikolaus; Christian Gieger; H-Erich Wichmann; Jurgita Sventoraityte; Limas Kupcinskas; Clive M Onnie; Maria Gazouli; Nicholas P Anagnou; David Strachan; Wendy L McArdle; Christopher G Mathew; Paul Rutgeerts; Séverine Vermeire; Morten H Vatn; Michael Krawczak; Philip Rosenstiel; Tom H Karlsen; Stefan Schreiber
Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).
Nature genetics 2010;42(4):292-4.
2010: Diana Rubin; Ulf Helwig; Michael Nothnagel; Ulrich R Fölsch; Stefan Schreiber; Jürgen Schrezenmeir
Association of postprandial and fasting triglycerides with traits of the metabolic syndrome in the Metabolic Intervention Cohort Kiel.
European journal of endocrinology / European Federation of Endocrine Societies 2010;162(4):719-27.
2010: Sven Kuenzel; Andreas Till; Michael Winkler; Robert Häsler; Simone Lipinski; Sascha Jung; Joachim Grötzinger; Helmut Fickenscher; Stefan Schreiber; Philip Rosenstiel
The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(4):1990-2000.
2010: Marlo Möller; Friederike Flachsbart; Andreas Till; Thorsten Thye; Rolf D Horstmann; Christian G Meyer; Ivy Osei; Paul D van Helden; Eileen G Hoal; Stefan Schreiber; Almut Nebel; Andre Franke
A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.
American journal of respiratory and critical care medicine 2010;181(4):388-93.
2010: Arne S Schaefer; Gesa M Richter; Michael Nothnagel; Thomas Manke; Henrik Dommisch; Gunnar Jacobs; Alexander Arlt; Philip Rosenstiel; Barbara Noack; Birte Groessner-Schreiber; Søren Jepsen; Bruno G Loos; Stefan Schreiber
A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis.
Human molecular genetics 2010;19(3):553-62.
2010: Markus Lommer; Alexandra-Sophie Roy; Markus Schilhabel; Stefan Schreiber; Philip Rosenstiel; Julie LaRoche
Recent transfer of an iron-regulated gene from the plastid to the nuclear genome in an oceanic diatom adapted to chronic iron limitation.
BMC genomics 2010;11():718.
2010: Sven Michel; Liming Liang; Martin Depner; Norman Klopp; Andreas Ruether; Ashish Kumar; Michaela Schedel; Christian Vogelberg; Erika von Mutius; Andrea von Berg; Albrecht Bufe; Ernst Rietschel; Andrea Heinzmann; Otto Laub; Burkhard Simma; Thomas Frischer; Jon Genuneit; Ivo Gut; Stefan Schreiber; Mark Lathrop; Thomas Illig; Michael Kabesch
Unifying candidate gene and GWAS Approaches in Asthma.
PloS one 2010;5(11):e13894.
2010: Marcel Kramer; Janne Boeck; Daniela Reichenbach; Christoph Kaether; Stefan Schreiber; Matthias Platzer; Philip Rosenstiel; Klaus Huse
NOD2-C2 - a novel NOD2 isoform activating NF-kappaB in a muramyl dipeptide-independent manner.
BMC research notes 2010;3():224.
2010: Marlo Möller; Almut Nebel; Paul D van Helden; Stefan Schreiber; Eileen G Hoal
Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study.
BMC infectious diseases 2010;10():154.
2010: Stefan Taudien; Marco Groth; Klaus Huse; Andreas Petzold; Karol Szafranski; Jochen Hampe; Philip Rosenstiel; Stefan Schreiber; Matthias Platzer
Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing.
BMC genomics 2010;11():252.
2010: A S Schaefer; G M Richter; Michael Nothnagel; M L Laine; A Rühling; C Schäfer; N Cordes; B Noack; M Folwaczny; J Glas; C Dörfer; Henrik Dommisch; B Groessner-Schreiber; Søren Jepsen; B G Loos; Stefan Schreiber
A 3' UTR transition within DEFB1 is associated with chronic and aggressive periodontitis.
Genes and immunity 2010;11(1):45-54.
2010: Patrick Linsel-Nitschke; Jörg Heeren; Zouhair Aherrahrou; Petra Bruse; Christian Gieger; Thomas Illig; Holger Prokisch; Katharina Heim; Angela Doering; Annette Peters; Thomas Meitinger; H-Erich Wichmann; Anke Hinney; Thomas Reinehr; Christian Roth; Jan R Ortlepp; Mouhidien Soufi; Alexander M Sattler; Jürgen Schaefer; Klaus Stark; Christian Hengstenberg; Arne Schaefer; Stefan Schreiber; Florian Kronenberg; Nilesh J Samani; Heribert Schunkert; Jeanette Erdmann
Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease.
Atherosclerosis 2010;208(1):183-9.
2010: Friederike Flachsbart; Amke Caliebe; Michael Nothnagel; Rabea Kleindorp; Susanna Nikolaus; Stefan Schreiber; Almut Nebel
Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals.
European journal of human genetics : EJHG 2010;18(1):59-61.
2009: Mike Ufer; Robert Häsler; Gunnar Jacobs; Sierk Haenisch; Sandra Lächelt; Frank Faltraco; Christian Sina; Philip Rosenstiel; Susanna Nikolaus; Stefan Schreiber; Ingolf Cascorbi
Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.
Pharmacogenomics 2009;10(12):1941-53.
2009: Philip Rosenstiel; Christian Sina; Andre Franke; Stefan Schreiber
Towards a molecular risk map--recent advances on the etiology of inflammatory bowel disease.
Seminars in immunology 2009;21(6):334-45.
2009: Christian Sina; Olga Gavrilova; Matti Förster; Andreas Till; Stefanie Derer; Friederike Hildebrand; Björn Raabe; Athena Chalaris; Jürgen Scheller; Ateequr Rehmann; Andre Franke; Stephan Ott; Robert Häsler; Susanna Nikolaus; Ulrich R Fölsch; Stefan Rose-John; Hui-Ping Jiang; Jun Li; Stefan Schreiber; Philip Rosenstiel
G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7514-22.
2009: U Müller-Ladner; RIEKE ALTEN; A Heiligenhaus; J Kekow; S Koletzko; U Mrowietz; T Ochsenkühn; M Radke; K Reich; M Rudwaleit; Stefan Schreiber
["TRECID", TNFalpha related chronic inflammatory diseases - a new multiple diseases bridging concept].
Deutsche medizinische Wochenschrift (1946) 2009;134(42):2132-6.
2009: Andrew A Hicks; Peter P Pramstaller; Asa Johansson; Veronique Vitart; Igor Rudan; Peter Ugocsai; Yurii Aulchenko; Christopher S Franklin; Gerhard Liebisch; Jeanette Erdmann; Inger Jonasson; Irina V Zorkoltseva; Cristian Pattaro; Caroline Hayward; Aaron Isaacs; Christian Hengstenberg; Susan Campbell; Carsten Gnewuch; A Cecilej W Janssens; Anatoly V Kirichenko; Inke R König; Fabio Marroni; Ozren Polasek; Ayse Demirkan; Ivana Kolcic; Christine Schwienbacher; Wilmar Igl; Zrinka Biloglav; Jacqueline C M Witteman; Irene Pichler; Ghazal Zaboli; Tatiana I Axenovich; Annette Peters; Stefan Schreiber; H-Erich Wichmann; Heribert Schunkert; Nick Hastie; Ben A Oostra; Sarah H Wild; Thomas Meitinger; Ulf Gyllensten; Cornelia M van Duijn; James F Wilson; Alan Wright; Gerd Schmitz; Harry Campbell
Genetic determinants of circulating sphingolipid concentrations in European populations.
PLoS genetics 2009;5(10):e1000672.
2009: Simone Lipinski; Andreas Till; Christian Sina; Alexander Arlt; Helmut Grasberger; Stefan Schreiber; Philip Rosenstiel
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses.
Journal of cell science 2009;122(Pt 19):3522-30.
2009: Michael A van Es; Jan Veldink; Christiaan G J Saris; Hylke M Blauw; Paul W J van Vught; Anna Birve; Robin Lemmens; Helenius J Schelhaas; Ewout J N Groen; Mark H B Huisman; Anneke J van der Kooi; Marianne de Visser; Caroline Dahlberg; Karol Estrada; Fernando Rivadeneira; Albert Hofman; Machiel J Zwarts; Perry T C van Doormaal; Dan Rujescu; Eric Strengman; Ina Giegling; Pierandrea Muglia; Barbara Tomik; Agnieszka Slowik; Andre G Uitterlinden; Corinna Hendrich; Stefan Waibel; Thomas Meyer; Albert C Ludolph; Jonathan D Glass; Shaun Purcell; Sven Cichon; Markus M Nöthen; H-Erich Wichmann; Stefan Schreiber; Sita H H M Vermeulen; Lambertus A Kiemeney; John H J Wokke; Simon Cronin; Russell L McLaughlin; Orla Hardiman; Katsumi Fumoto; R Jeroen Pasterkamp; Vincent Meininger; Judith Melki; P Nigel Leigh; Christopher Shaw; John E Landers; Ammar Al-Chalabi; Robert H Brown; Wim Robberecht; Peter M Andersen; Roel A Ophoff; Leonard H van den Berg
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis.
Nature genetics 2009;41(10):1083-7.
2009: Almut Nebel; Friederike Flachsbart; Andreas Till; Amke Caliebe; Hélène Blanché; Alexander Arlt; Robert Häsler; Gunnar Jacobs; Rabea Kleindorp; Andre Franke; Binghui Shen; Susanna Nikolaus; Michael Krawczak; Philip Rosenstiel; Stefan Schreiber
A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians.
Mechanisms of ageing and development 2009;130(10):691-9.
2009: Karol Estrada; Michael Krawczak; Stefan Schreiber; Kate van Duijn; Lisette Stolk; Joyce B J van Meurs; Fan Liu; Brenda W J H Penninx; Jan H Smit; Nicole Vogelzangs; Jouke-Jan Hottenga; Gonneke Willemsen; Eco J C De Geus; Mattias Lorentzon; Huberta von Eller-Eberstein; Paul Lips; Natascha Schoor; Victor Pop; Jules de Keijzer; Albert Hofman; Yurii Aulchenko; Ben A Oostra; Claes Ohlsson; Dorret I Boomsma; André G Uitterlinden; C.M. Duijn; Fernando Rivadeneira; Manfred Kayser
A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation.
Human molecular genetics 2009;18(18):3516-24.
2009: Marcus Seeger; Burkhard Bewig; Rainer Günther; Clemens Schafmayer; Bernd Vollnberg; Diana Rubin; Christine Hoell; Stefan Schreiber; Ulrich R Fölsch; Jochen Hampe
Terminal part of thoracic duct: high-resolution US imaging.
Radiology 2009;252(3):897-904.
2009: Liesbet Henckaerts; Kristel van Steen; Isabel Verstreken; Isabelle Cleynen; Andre Franke; Stefan Schreiber; Paul Rutgeerts; Severine Vermeire
Genetic risk profiling and prediction of disease course in Crohn's disease patients.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009;7(9):972-980.e2.
2009: Xinhua Yu; S Wieczorek; Andre Franke; H Yin; M Pierer; C Sina; T H Karlsen; K M Boberg; A Bergquist; M Kunz; T Witte; W L Gross; Jörg T Epplen; M E Alarcón-Riquelme; Stefan Schreiber; Saleh M Ibrahim
Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases.
Genes and immunity 2009;10(6):601-5.
2009: Bruno G Loos; Andreas Fiebig; M Nothnagel; S Jepsen; B Groessner-Schreiber; Andre Franke; P M Jervøe-Storm; Karl Schenck; Ubele van der Velden; Stefan Schreiber
NOD1 gene polymorphisms in relation to aggressive periodontitis.
Innate immunity 2009;15(4):225-32.
2009: Brian G Feagan; Geoffroy Coteur; Seng Tan; Dorothy L Keininger; Stefan Schreiber
Clinically meaningful improvement in health-related quality of life in a randomized controlled trial of certolizumab pegol maintenance therapy for Crohn's disease.
The American journal of gastroenterology 2009;104(8):1976-83.
2009: David Ellinghaus; Stefan Schreiber; Andre Franke; Michael Nothnagel
Current software for genotype imputation.
Human genomics 2009;3(4):371-80.
2009: Jens Treutlein; Sven Cichon; Monika Ridinger; Norbert Wodarz; Michael Soyka; Peter Zill; Wolfgang Maier; Rainald Moessner; Wolfgang Gaebel; Norbert Dahmen; Christoph Fehr; Norbert Scherbaum; Michael Steffens; Kerstin U Ludwig; Josef Frank; H-Erich Wichmann; Stefan Schreiber; Nico Dragano; Wolfgang Sommer; Fernando Leonardi-Essmann; Anbarasu Lourdusamy; Peter J Gebicke-Haerter; Thomas F Wienker; Patrick F Sullivan; Markus M Nöthen; Falk Kiefer; Rainer Spanagel; Karl Mann; Marcella Rietschel
Genome-wide association study of alcohol dependence.
Archives of general psychiatry 2009;66(7):773-84.
2009: Stephan Hellmig; Tobias Bartscht; Wolfgang Fischbach; Stephan Johannes Ott; Philip Rosenstiel; Wolfram Klapper; Ulrich Robert Fölsch; Stefan Schreiber
Germline variations of the MALT1 gene as risk factors in the development of primary gastric B-cell lymphoma.
European journal of cancer (Oxford, England : 1990) 2009;45(10):1865-70.
2009: Jean-Frédéric Colombel; D A Schwartz; William J Sandborn; M A Kamm; Geert D'Haens; Paul Rutgeerts; Robert Enns; Remo Panaccione; Stefan Schreiber; J Li; J D Kent; K G Lomax; Paul F Pollack
Adalimumab for the treatment of fistulas in patients with Crohn's disease.
Gut 2009;58(7):940-8.
2009: Timothy Tehua Lu; Oscar Lao; Michael Nothnagel; Olaf Junge; Sandra Freitag-Wolf; Amke Caliebe; Miroslava Balascakova; Jaume Bertranpetit; Laurence Albert Bindoff; David Comas; Gunilla Holmlund; Anastasia Kouvatsi; Milan Macek Jr.; Isabelle Mollet; Finn Nielsen; Walther Parson; Jukka Palo; Rafal Ploski; Antti Sajantila; Adriano Tagliabracci; Ulrik Gether; Thomas Werge; Fernando Rivadeneira; Albert Hofman; André Gerardus Uitterlinden; Christian Gieger; Heinz-Erich Wichmann; Andreas Ruether; Stefan Schreiber; Christian Becker; Peter Nürnberg; Matthew Roberts Nelson; Manfred Kayser; Michael Krawczak
An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population.
European journal of human genetics : EJHG 2009;17(7):967-75.
2009: Robert Häsler; Alexander Begun; Sandra Freitag-Wolf; Martin Kerick; Nancy Mah; Aida Zvirbliene; Martina E Spehlmann; Nicole von Wurmb-Schwark; Limas Kupcinskas; Philip Rosenstiel; Stefan Schreiber
Genetic control of global gene expression levels in the intestinal mucosa: a human twin study.
Physiological genomics 2009;38(1):73-9.
2009: Dieco Würdemann; Brian J Tindall; Rüdiger Pukall; Heinrich Lünsdorf; Carsten Strömpl; Theresa Namuth; Hannes Nahrstedt; Melissa Wos-Oxley; Stephan Ott; Stefan Schreiber; Kenneth N Timmis; Andrew P A Oxley
Gordonibacter pamelaeae gen. nov., sp. nov., a new member of the Coriobacteriaceae isolated from a patient with Crohn's disease, and reclassification of Eggerthella hongkongensis Lau et al. 2006 as Paraeggerthella hongkongensis gen. nov., comb. nov.
International journal of systematic and evolutionary microbiology 2009;59(Pt 6):1405-15.
2009: Stefanie Derer; Georg H Waetzig; Dirk Seegert; Susanna Nikolaus; Stefan Schreiber; Philip Rosenstiel
A possible link between TIMP-1 induction and response to infliximab.
Gut 2009;58(6):888; author reply 888-9.
2009: Stefan Schreiber
The genetic universe of inflammatory bowel disease.
Gastroenterology 2009;136(7):2402-3.
2009: Delia Lorenz; Stephan Klebe; Giovanni Stevanin; Sandra Thier; Almut Nebel; JOSUE FEINGOLD; Henrik Frederiksen; Elodie Denis; Kaare Christensen; Stefan Schreiber; Alexis Brice; Günther Deuschl; Alexandra Dürr
Dopamine receptor D3 gene and essential tremor in large series of German, Danish and French patients.
European journal of human genetics : EJHG 2009;17(6):766-73.
2009: Katja Heilmann; Ute Hoffmann; Ellen Witte; Christoph Loddenkemper; Christian Sina; Stefan Schreiber; Claudia Hayford; Pamela Holzlöhner; Kerstin Wolk; Elianne Tchatchou; Verena Moos; Martin Zeitz; Robert Sabat; Ursula Günthert; Bianca Maria Wittig
Osteopontin as two-sided mediator of intestinal inflammation.
Journal of cellular and molecular medicine 2009;13(6):1162-74.
2009: Kathrin Suttner; Philip Rosenstiel; Martin Depner; Michaela Schedel; Leonardo A Pinto; Andreas Ruether; Jerzy Adamski; Norman Klopp; Thomas Illig; Christian Vogelberg; Stefan Schreiber; Erika von Mutius; Michael Kabesch
TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants.
The Journal of allergy and clinical immunology 2009;123(5):1062-8, 1068.e1-8.
2009: Jorge Esparza-Gordillo; Stephan Weidinger; Regina Fölster-Holst; Anja Bauerfeind; Franz Ruschendorf; Giannino Patone; Klaus Rohde; Ingo Marenholz; Florian Schulz; Tamara Kerscher; Norbert Hubner; Ulrich Wahn; Stefan Schreiber; Andre Franke; Rainer Vogler; Simon Heath; Hansjörg Baurecht; Natalija Novak; Elke Rodriguez; Thomas Illig; Min Ae Lee-Kirsch; Andrzej Ciechanowicz; Michael Kurek; Tereza Piskackova; Milan Macek Jr.; Young-Ae Lee; Andreas Ruether
A common variant on chromosome 11q13 is associated with atopic dermatitis.
Nature genetics 2009;41(5):596-601.
2009: Abdou ElSharawy; Bernd Hundrieser; Mario Brosch; Michael Wittig; Klaus Huse; Matthias Platzer; Albert Becker; Matthias Simon; Philip Rosenstiel; Stefan Schreiber; Michael Krawczak; Jochen Hampe
Systematic evaluation of the effect of common SNPs on pre-mRNA splicing.
Human mutation 2009;30(4):625-32.
2009: Thomas C G Bosch; René Augustin; Friederike Anton-Erxleben; Sebastian Fraune; Georg Hemmrich; Holger Zill; Philip Rosenstiel; Gunnar Jacobs; Stefan Schreiber; Joachim Grötzinger; Mareike Stanisak; Joachim Grötzinger; Sascha Jung; Rainer Podschun; Joachim Bartels; Jürgen Harder; Jens Schröder
Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.
Developmental and comparative immunology 2009;33(4):559-69.
2009: J Müller-Quernheim; M Schürmann; S Hofmann; Karoline Gaede; A Fischer; A Prasse; Gernot Zissel; Stefan Schreiber
[Genetics of sarcoidosis: a key to understanding its pathogenesis].
Pneumologie (Stuttgart, Germany) 2009;63(3):166-75.
2009: Dieter Kabelitz; Stefan Schreiber
[Autoimmunity. Physiological control mechanisms and pathways to autoimmune disease].
Der Internist 2009;50(3):267-75.
2009: Jeanette Erdmann; Anika Grosshennig; Peter S Braund; Inke R König; Christian Hengstenberg; Alistair Hall; Patrick Linsel-Nitschke; Sekar Kathiresan; Ben Wright; David-Alexandre Trégouët; Francois Cambien; Petra Bruse; Zouhair Aherrahrou; Arnika K Wagner; Klaus Stark; Stephen M Schwartz; Veikko Salomaa; Roberto Elosua; Olle Melander; Benjamin F Voight; Christopher J O'Donnell; Leena Peltonen; David S Siscovick; David Altshuler; Piera Angelica Merlini; Flora Peyvandi; Luisa Bernardinelli; Diego Ardissino; Arne Schillert; Stefan Blankenberg; Tanja Zeller; Philipp Wild; Daniel Schwarz; Laurence Tiret; Claire Perret; Stefan Schreiber; Nour Eddine El Mokhtari; Arne Schäfer; Winfried März; Wilfried Renner; Peter Bugert; Harald Klüter; Jürgen Schrezenmeir; Diana Rubin; Stephen G Ball; Anthony J Balmforth; H-Erich Wichmann; Thomas Meitinger; Marcus Fischer; Christa Meisinger; Jens Baumert; Annette Peters; Willem H Ouwehand; Panos Deloukas; John R Thompson; Andreas Ziegler; Nilesh J Samani; Heribert Schunkert
New susceptibility locus for coronary artery disease on chromosome 3q22.3.
Nature genetics 2009;41(3):280-2.
2009: David-Alexandre Trégouët; Inke R König; Jeanette Erdmann; Alexandru Munteanu; Peter S Braund; Alistair Hall; Anika Grosshennig; Patrick Linsel-Nitschke; Claire Perret; Maylis DeSuremain; Thomas Meitinger; Ben J Wright; Michael Preuss; Anthony J Balmforth; Stephen G Ball; Christa Meisinger; Cécile Germain; Alun Evans; Dominique Arveiler; Gérald Luc; Jean-Bernard Ruidavets; Caroline Morrison; Pim van der Harst; Stefan Schreiber; Katharina Neureuther; Arne Schäfer; Peter Bugert; Nour E El Mokhtari; Jürgen Schrezenmeir; Klaus Stark; Diana Rubin; H-Erich Wichmann; Christian Hengstenberg; Willem Ouwehand; Andreas Ziegler; Laurence Tiret; John R Thompson; Francois Cambien; Heribert Schunkert; Nilesh J Samani
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease.
Nature genetics 2009;41(3):283-5.
2009: Sekar Kathiresan; Benjamin F Voight; Shaun Purcell; Kiran Musunuru; Diego Ardissino; Pier M Mannucci; Sonia Anand; James C Engert; Nilesh J Samani; Heribert Schunkert; Jeanette Erdmann; Muredach P Reilly; Daniel J Rader; Thomas Morgan; John A Spertus; Monika Stoll; Domenico Girelli; Pascal P McKeown; Chris C Patterson; David S Siscovick; Christopher J O'Donnell; Roberto Elosua; Leena Peltonen; Veikko Salomaa; Stephen M Schwartz; Olle Melander; David Altshuler; Diego Ardissino; Pier Angelica Merlini; Carlo Berzuini; Luisa Bernardinelli; Flora Peyvandi; Marco Tubaro; Patrizia Celli; Maurizio Ferrario; Raffaela Fetiveau; Nicola Marziliano; Giorgio Casari; Michele Galli; Flavio Ribichini; Marco Rossi; francesco bernardi; Pietro Zonzin; Alberto Piazza; Pier M Mannucci; Stephen M Schwartz; David S Siscovick; Jean Yee; Yechiel Friedlander; Roberto Elosua; Jaume Marrugat; Gavin Lucas; Isaac Subirana; Joan Sala; Rafael Ramos; Sekar Kathiresan; James B Meigs; Gordon Williams; David M Nathan; Calum A MacRae; Christopher J O'Donnell; Veikko Salomaa; Aki S Havulinna; Leena Peltonen; Olle Melander; Goran Berglund; Benjamin F Voight; Sekar Kathiresan; Joel N Hirschhorn; Rosanna Asselta; Stefano Duga; Marta Spreafico; Kiran Musunuru; Mark J Daly; Shaun Purcell; Benjamin F Voight; Shaun Purcell; James Nemesh; Joshua M Korn; Steven A McCarroll; Stephen M Schwartz; Jean Yee; Sekar Kathiresan; Gavin Lucas; Isaac Subirana; Roberto Elosua; Aarti Surti; Candace Guiducci; Lauren Gianniny; Daniel Mirel; Melissa Parkin; Noel Burtt; Stacey B Gabriel; Nilesh J Samani; John R Thompson; Peter S Braund; Benjamin J Wright; Anthony J Balmforth; Stephen G Ball; Heribert Schunkert; Jeanette Erdmann; Patrick Linsel-Nitschke; Wolfgang Lieb; Andreas Ziegler; Inke König; Christian Hengstenberg; Marcus Fischer; Klaus Stark; Anika Grosshennig; Michael Preuss; H-Erich Wichmann; Stefan Schreiber; Heribert Schunkert; Nilesh J Samani; Jeanette Erdmann; Willem Ouwehand; Christian Hengstenberg; Panos Deloukas; Michael Scholz; Francois Cambien; Muredach P Reilly; Mingyao Li; Zhen Chen; Robert Wilensky; William Matthai; Atif Qasim; Hakon H Hakonarson; Joe Devaney; Mary-Susan Burnett; Augusto D Pichard; Kenneth M Kent; Lowell Satler; Joseph M Lindsay; Ron Waksman; Christopher W Knouff; Dawn M Waterworth; Max C Walker; Vincent Mooser; Stephen E Epstein; Daniel J Rader; Thomas Scheffold; Klaus Berger; Monika Stoll; Andreas Huge; Domenico Girelli; Nicola Martinelli; Oliviero Olivieri; Roberto Corrocher; Thomas Morgan; John A Spertus; Pascal McKeown; Chris C Patterson; Heribert Schunkert; Erdmann Erdmann; Patrick Linsel-Nitschke; Wolfgang Lieb; Andreas Ziegler; Inke R König; Christian Hengstenberg; Marcus Fischer; Klaus Stark; Anika Grosshennig; Michael Preuss; H-Erich Wichmann; Stefan Schreiber; Hilma Hólm; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Kari Stefansson; James C Engert; Ron Do; Changchun Xie; Sonia Anand; Sekar Kathiresan; Diego Ardissino; Pier M Mannucci; David Siscovick; Christopher J O'Donnell; Nilesh J Samani; Olle Melander; Roberto Elosua; Leena Peltonen; Veikko Salomaa; Stephen M Schwartz; Alistair Hall; David Altshuler
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.
Nature genetics 2009;41(3):334-41.
2009: Caroline End; Floris J Bikker; Marcus Renner; Gaby Bergmann; Stefan Lyer; Stephanie Blaich; Melanie Hudler; Burkhard Helmke; Nikolaus Gassler; Frank Autschbach; Antoon J M Ligtenberg; Axel Benner; Uffe Holmskov; Peter Schirmacher; Arie V Nieuw Amerongen; Philip Rosenstiel; Christian Sina; Andre Franke; Mathias Hafner; Petra Kioschis; Stefan Schreiber; Annemarie Poustka; Jan Mollenhauer
DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands.
European journal of immunology 2009;39(3):833-42.
2009: Rinse K Weersma; Pieter C F Stokkers; Isabelle Cleynen; Simone C S Wolfkamp; Liesbet Henckaerts; Stefan Schreiber; Gerard Dijkstra; Andre Franke; Ilja M Nolte; Paul Rutgeerts; Cisca Wijmenga; Severine Vermeire
Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort.
The American journal of gastroenterology 2009;104(3):630-8.
2009: Marlo Möller; Almut Nebel; Ruta Valentonyte; Paul D van Helden; Stefan Schreiber; Eileen G Hoal
Investigation of chromosome 17 candidate genes in susceptibility to TB in a South African population.
Tuberculosis (Edinburgh, Scotland) 2009;89(2):189-94.
2009: Michael Nothnagel; David Ellinghaus; Stefan Schreiber; Michael Krawczak; Andre Franke
A comprehensive evaluation of SNP genotype imputation.
Human genetics 2009;125(2):163-71.
2009: Frauke Friedrichs; Christian Zugck; Gerd-Jörg Rauch; Boris Ivandic; Dieter Weichenhan; Margit Müller-Bardorff; Benjamin Meder; Nour Eddine El Mokhtari; Vera Regitz-Zagrosek; Roland Hetzer; Arne Schäfer; Stefan Schreiber; Jian Chen; Isaac Neuhaus; Ruiru Ji; Nathan Siemers; Norbert Frey; Wolfgang Rottbauer; Hugo A Katus; Monika Stoll
HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy.
Genome research 2009;19(3):395-403.
2009: Inger Camilla Solberg; Idar Lygren; Milada Cvancarova; Jørgen Jahnsen; Njål Stray; Jostein Sauar; Stefan Schreiber; Bjørn Moum; Morten Vatn
Predictive value of serologic markers in a population-based Norwegian cohort with inflammatory bowel disease.
Inflammatory bowel diseases 2009;15(3):406-14.
2009: Friederike Flachsbart; Amke Caliebe; Rabea Kleindorp; Hélène Blanché; Huberta von Eller-Eberstein; Susanna Nikolaus; Stefan Schreiber; Almut Nebel
Association of FOXO3A variation with human longevity confirmed in German centenarians.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2700-5.
2009: Arne S Schaefer; Gesa M Richter; Birte Groessner-Schreiber; Barbara Noack; Michael Nothnagel; Nour Eddine El Mokhtari; Bruno G Loos; Søren Jepsen; Stefan Schreiber
Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis.
PLoS genetics 2009;5(2):e1000378.
2009: H Fuchs; V Gailus-Durner; T Adler; J A Aguilar Pimentel; L Becker; I Bolle; M Brielmeier; J Calzada-Wack; C Dalke; N Ehrhardt; N Fasnacht; B Ferwagner; U Frischmann; W Hans; S M Hölter; G Hölzlwimmer; M Horsch; A Javaheri; M Kallnik; E Kling; C Lengger; H Maier; I Mossbrugger; C Mörth; B Naton; Ulrich Nöth; B Pasche; C Prehn; G Przemeck; O Puk; I Racz; B Rathkolb; J Rozman; K Schäble; R Schreiner; A Schrewe; C Sina; R Steinkamp; F Thiele; M Willershäuser; R Zeh; J Adamski; D H Busch; J Beckers; H Behrendt; H Daniel; I Esposito; J Favor; J Graw; G Heldmaier; H Höfler; B Ivandic; H Katus; Martin Klingenspor; T Klopstock; A Lengeling; M Mempel; Werner Muller; S Neschen; M Ollert; L Quintanilla-Martinez; Philip Rosenstiel; J Schmidt; Stefan Schreiber; K Schughart; H Schulz; E Wolf; W Wurst; A Zimmer; M Hrabé de Angelis
The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models.
Current pharmaceutical biotechnology 2009;10(2):236-43.
2009: Rajan P Nair; Kristina Callis Duffin; Cynthia Helms; Jun Ding; Philip Stuart; David Goldgar; Johann Gudjonsson; Yun Li; Trilokraj Tejasvi; Bing-Jian Feng; Andreas Ruether; Stefan Schreiber; Michael Weichenthal; Dafna Gladman; Proton Rahman; Steven J Schrodi; Sampath Prahalad; Stephen L Guthery; Judith Fischer; Wilson Liao; Pui-Yan Kwok; Alan Menter; G Mark Lathrop; Carol A Wise; Ann B Begovich; John J Voorhees; James T Elder; Gerald G Krueger; Anne M Bowcock; Goncalo Abecasis
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
Nature genetics 2009;41(2):199-204.
2009: Ingo Helbig; Heather C Mefford; Andrew J Sharp; Michel Guipponi; Marco Fichera; Andre Franke; Hiltrud Muhle; Carolien de Kovel; Carl Baker; Sarah von Spiczak; Katherine L Kron; Ines Steinich; Ailing A Kleefuss-Lie; Costin Leu; Verena Gaus; Bettina Schmitz; Karl M Klein; Philipp S Reif; Felix Rosenow; Yvonne Weber; Holger Lerche; Fritz Zimprich; Lydia Urak; Karoline Fuchs; Martha Feucht; Pierre Genton; Pierre Thomas; Frank Visscher; Gerrit-Jan de Haan; Rikke Steensbjerre Møller; Helle Hjalgrim; Daniela Luciano; Michael Wittig; Michael Nothnagel; Christian E Elger; Peter Nürnberg; Corrado Romano; Alain Malafosse; Bobby P C Koeleman; Dick Lindhout; Ulrich Stephani; Stefan Schreiber; Evan E Eichler; Thomas Sander
15q13.3 microdeletions increase risk of idiopathic generalized epilepsy.
Nature genetics 2009;41(2):160-2.
2009: Philip Rosenstiel; Eva E R Philipp; Stefan Schreiber; Thomas C G Bosch
Evolution and function of innate immune receptors--insights from marine invertebrates.
Journal of innate immunity 2009;1(4):291-300.
2009: Nikolaus Möckelmann; Witigo von Schönfels; Stephan Buch; Oliver von Kampen; Bence Sipos; Jan-Hendrik Egberts; Philip Rosenstiel; Andre Franke; Mario Brosch; Sebastian Hinz; Christian Röder; Holger Kalthoff; Ulrich R Fölsch; Michael Krawczak; Stefan Schreiber; Clemens Dieter Bröring; Juergen Tepel; Clemens Schafmayer; Jochen Hampe
Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer.
BMC gastroenterology 2009;9():79.
2009: Philip Rosenstiel; Stefan Schreiber
NOD-like receptors--pivotal guardians of the immunological integrity of barrier organs.
Advances in experimental medicine and biology 2009;653():35-47.
2009: J Herrmann; D Rubin; R Häsler; U Helwig; M Pfeuffer; A Auinger; C Laue; P Winkler; Stefan Schreiber; D Bell; Jürgen Schrezenmeir
Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study.
Lipids in health and disease 2009;8():35.
2009: Nadine Steubesand; Karlheinz Kiehne; Gabriele Brunke; Rene Pahl; Karina Reiss; Karl-Heinz Herzig; Sabine Schubert; Stefan Schreiber; Ulrich R Fölsch; Philip Rosenstiel; Alexander Arlt
The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis.
BMC immunology 2009;10():36.
2009: Mari Nelis; Tõnu Esko; Reedik Mägi; Fritz Zimprich; Alexander Zimprich; Draga Toncheva; Sena Karachanak; Tereza Piskácková; Ivan Balascák; Leena Peltonen; Eveliina Jakkula; Karola Rehnström; Mark Lathrop; Simon Heath; Pilar Galan; Stefan Schreiber; Thomas Meitinger; Arne Pfeufer; H-Erich Wichmann; Béla Melegh; Noémi Polgár; Daniela Toniolo; Paolo Gasparini; Pio D'Adamo; Janis Klovins; Liene Nikitina-Zake; Vaidutis Kucinskas; Jūrate Kasnauskiene; Jan Lubinski; Tadeusz Debniak; Svetlana Limborska; Andrey Khrunin; Xavier Estivill; Raquel Rabionet; Sara Marsal; Antonio Julià; Stylianos Antonarakis; Samuel Deutsch; Christelle Borel; Homa Attar; Maryline Gagnebin; Milan Macek Jr.; Michael Krawczak; Maido Remm; Andres Metspalu
Genetic structure of Europeans: a view from the North-East.
PloS one 2009;4(5):e5472.
2009: Markus Teuber; Michael H Wenz; Stefan Schreiber; Andre Franke
GMFilter and SXTestPlate: software tools for improving the SNPlex genotyping system.
BMC bioinformatics 2009;10():81.
2009: Gøri Perminow; Stephan Brackmann; Lars G Lyckander; Andre Franke; Arne S Borthne; Andreas Rydning; Geir Aamodt; Stefan Schreiber; Morten Vatn
A characterization in childhood inflammatory bowel disease, a new population-based inception cohort from South-Eastern Norway, 2005-07, showing increased incidence in Crohn's disease.
Scandinavian journal of gastroenterology 2009;44(4):446-56.
2009: Kathrin Suttner; Isabell Ruoss; Philip Rosenstiel; Martin Depner; Leonardo A Pinto; Michaela Schedel; Jerzy Adamski; Thomas Illig; Stefan Schreiber; Erika von Mutius; Michael Kabesch
HLX1 gene variants influence the development of childhood asthma.
The Journal of allergy and clinical immunology 2009;123(1):82-88.e6.
2009: Clemens Schafmayer; Stephan Buch; Henry Völzke; Witigo von Schönfels; Jan-Hendrik Egberts; Bodo Schniewind; Mario Brosch; Andreas Ruether; Andre Franke; Micaela Mathiak; Bence Sipos; Tobias Henopp; Jasmin Catalcali; Stephan Hellmig; Abdou ElSharawy; Alexander Katalinic; Markus M Lerch; Ulrich John; Ulrich R Fölsch; Fred Fändrich; Holger Kalthoff; Stefan Schreiber; Michael Krawczak; Juergen Tepel; Jochen Hampe
Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample.
International journal of cancer. Journal international du cancer 2009;124(1):75-80.
2009: Michael A Kamm; Gary R Lichtenstein; William J Sandborn; Stefan Schreiber; Kirstin Lees; Karen Barrett; Raymond Joseph
Effect of extended MMX mesalamine therapy for acute, mild-to-moderate ulcerative colitis.
Inflammatory bowel diseases 2009;15(1):1-8.
2008: Simon Heath; Ivo Gut; Paul Brennan; James D McKay; Vladimir Bencko; Eleonora Fabianova; Lenka Foretova; Michael Georges; vladimir janout; Michael Kabesch; Hans E Krokan; Maiken B Elvestad; Jolanta Lissowska; Dana Mates; Peter Rudnai; Frank Skorpen; Stefan Schreiber; José M Soria; Ann-Christine Syvänen; Pierre Meneton; Serge Herçberg; Pilar Galan; Neonilia Szeszenia-Dabrowska; David Zaridze; Emmanuel Génin; Lon R Cardon; Mark Lathrop
Investigation of the fine structure of European populations with applications to disease association studies.
European journal of human genetics : EJHG 2008;16(12):1413-29.
2008: Tanja Kuehbacher; Ateequr Rehman; Patricia Lepage; Stephan Hellmig; Ulrich R Fölsch; Stefan Schreiber; Stephan J Ott
Intestinal TM7 bacterial phylogenies in active inflammatory bowel disease.
Journal of medical microbiology 2008;57(Pt 12):1569-76.
2008: Richard S Houlston; Emily Webb; Peter Broderick; Alan Pittman; Maria Chiara Di Bernardo; Steven Lubbe; Ian Chandler; Jayaram Vijayakrishnan; Kate Sullivan; Steven Penegar; Luis Carvajal Carmona; Kimberley Howarth; Emma Jaeger; Sarah L Spain; Axel Walther; Ella Barclay; Lynn Martin; Maggie Gorman; Enric Domingo; Ana S Teixeira; David Kerr; Jean-Baptiste Cazier; Iina Niittymäki; Sari Tuupanen; Auli Karhu; Lauri A Aaltonen; axel walther; Susan M Farrington; Albert Tenesa; James G D Prendergast; Rebecca A Barnetson; Roseanne Cetnarskyj; Mary E Porteous; Paul D P Pharoah; Thibaud Koessler; Jochen Hampe; Stephan Buch; Clemens Schafmayer; Jurgen Tepel; Stefan Schreiber; Henry Völzke; Jenny Chang-Claude; Michael Hoffmeister; Hermann Brenner; Brent W Zanke; Alexandre Montpetit; Thomas J Hudson; Steven Gallinger; Harry Campbell; Malcolm G Dunlop
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
Nature genetics 2008;40(12):1426-35.
2008: Brian G Feagan; Remo Panaccione; William J Sandborn; Geert D'Haens; Stefan Schreiber; Paul J Rutgeerts; Edward V Loftus; Kathleen G Lomax; Andrew P Yu; Eric Q Wu; Jingdong Chao; Parvez Mulani
Effects of adalimumab therapy on incidence of hospitalization and surgery in Crohn's disease: results from the CHARM study.
Gastroenterology 2008;135(5):1493-9.
2008: Andre Franke; Tobias Balschun; Tom H Karlsen; Jurgita Sventoraityte; Susanna Nikolaus; Gabriele Mayr; Francisco S Domingues; Mario Albrecht; Michael Nothnagel; David Ellinghaus; Christian Sina; Clive M Onnie; Rinse Weersma; Pieter C F Stokkers; Cisca Wijmenga; Maria Gazouli; David Strachan; Wendy L McArdle; Séverine Vermeire; Paul Rutgeerts; Philip Rosenstiel; Michael Krawczak; Morten Vatn; Christopher G Mathew; Stefan Schreiber
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.
Nature genetics 2008;40(11):1319-23.
2008: Andreas Fiebig; Søren Jepsen; Bruno G Loos; Claudia Scholz; Christine Schäfer; Andreas Rühling; Michael Nothnagel; Peter Eickholz; Ubele van der Velden; Karl Schenck; Stefan Schreiber; Birte Grössner-Schreiber
Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population.
Genomics 2008;92(5):309-15.
2008: Andre Franke; Annegret Fischer; Michael Nothnagel; Christian Becker; Nils Grabe; Andreas Till; Tim Lu; Joachim Müller-Quernheim; Michael Wittig; Alexander Hermann; Tobias Balschun; Sylvia Hofmann; Regina Niemiec; Sabrina Schulz; Jochen Hampe; Susanna Nikolaus; Peter Nürnberg; Michael Krawczak; Manfred Schürmann; Philip Rosenstiel; Almut Nebel; Stefan Schreiber
Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.
Gastroenterology 2008;135(4):1207-15.
2008: Stephan J Ott; Sophie Plamondon; Ailsa Hart; Alexander Begun; Ateequr Rehman; Michael A Kamm; Stefan Schreiber
Dynamics of the mucosa-associated flora in ulcerative colitis patients during remission and clinical relapse.
Journal of clinical microbiology 2008;46(10):3510-3.
2008: Marco Groth; Karol Szafranski; Stefan Taudien; Klaus Huse; Oliver Mueller; Philip Rosenstiel; Anders O H Nygren; Stefan Schreiber; Gerd Birkenmeier; Matthias Platzer
High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.
Human mutation 2008;29(10):1247-54.
2008: C Pena-Rossi; Stefan Schreiber; G Golubovic; A Mertz-Nielsen; J Panes; D Rachmilewitz; M J Shieh; V I Simanenkov; D Stanton; H Graffner
Clinical trial: a multicentre, randomized, double-blind, placebo-controlled, dose-finding, phase II study of subcutaneous interferon-beta-la in moderately active ulcerative colitis.
Alimentary pharmacology & therapeutics 2008;28(6):758-67.
2008: Remo Panaccione; P Rutgeerts; William J Sandborn; Brian G Feagan; Stefan Schreiber; S Ghosh
Review article: treatment algorithms to maximize remission and minimize corticosteroid dependence in patients with inflammatory bowel disease.
Alimentary pharmacology & therapeutics 2008;28(6):674-88.
2008: Arthur Kaser; Ann-Hwee Lee; Andre Franke; Jonathan N Glickman; Sebastian Zeissig; Herbert Tilg; Edward E S Nieuwenhuis; Darren E Higgins; Stefan Schreiber; Laurie H Glimcher; Richard S Blumberg
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.
Cell 2008;134(5):743-56.
2008: Sylvia Hofmann; Andre Franke; Annegret Fischer; Gunnar Jacobs; Michael Nothnagel; Karoline Gaede; Manfred Schürmann; Joachim Müller-Quernheim; Michael Krawczak; Philip Rosenstiel; Stefan Schreiber
Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis.
Nature genetics 2008;40(9):1103-6.
2008: J C Hoffmann; J C Preiss; F Autschbach; H J Buhr; W Häuser; K Herrlinger; W Höhne; S Koletzko; C F Krieglstein; W Kruis; H Matthes; G Moser; M Reinshagen; G Rogler; Stefan Schreiber; Andreas Schreyer; B Sido; B Siegmund; A Stallmach; B Bokemeyer; E F Stange; M Zeitz
[Clinical practice guideline on diagnosis and treatment of Crohn's disease].
Zeitschrift für Gastroenterologie 2008;46(9):1094-146.
2008: J C Hoffmann; F Autschbach; B Bokemeyer; H-J Buhr; K Herrlinger; W Höhne; C Krieglstein; W Kruis; G Moser; J C Preiss; M Reinshagen; G Rogler; Stefan Schreiber; Andreas Schreyer; B Siegmund; A Stallmach; E F Stange; M Zeitz
[Short version of the updated German S3 (level 3) guideline on diagnosis and treatment of Crohn's disease].
Deutsche medizinische Wochenschrift (1946) 2008;133(38):1924-9.
2008: Walter Reinisch; Julian Panés; Marc Lémann; Stefan Schreiber; B Feagan; Steven Schmidt; Giacomo C Sturniolo; T Mikhailova; Olga Alexeeva; L Sanna; T Haas; S Korom; H Mayer
A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease.
The American journal of gastroenterology 2008;103(9):2284-92.
2008: Joachim Müller-Quernheim; Manfred Schürmann; Sylvia Hofmann; Karoline Gaede; Annegret Fischer; Antje Prasse; Gernot Zissel; Stefan Schreiber
Genetics of sarcoidosis.
Clinics in chest medicine 2008;29(3):391-414, viii.
2008: Oscar Lao; Timothy T Lu; Michael Nothnagel; Olaf Junge; Sandra Freitag-Wolf; Amke Caliebe; Miroslava Balascakova; Jaume Bertranpetit; Laurence A Bindoff; David Comas; Gunilla Holmlund; Anastasia Kouvatsi; Milan Macek Jr.; Isabelle Mollet; Walther Parson; Jukka Palo; Rafal Ploski; Antti Sajantila; Adriano Tagliabracci; Ulrik Gether; Thomas Werge; Fernando Rivadeneira; Albert Hofman; André G Uitterlinden; Christian Gieger; Heinz-Erich Wichmann; Andreas Rüther; Stefan Schreiber; Christian Becker; Peter Nürnberg; Matthew Nelson; Michael Krawczak; Manfred Kayser
Correlation between genetic and geographic structure in Europe.
Current biology : CB 2008;18(16):1241-8.
2008: Susanna Nikolaus; Stefan Schreiber
[Anti-TNF biologics in the treatment of chronic inflammatory bowel disease].
Der Internist 2008;49(8):947-8, 950-3.
2008: Clemens Schafmayer; Sandra Freitag-Wolf; Heike Wolken; Stephan Buch; Mario Brosch; Jan-Hendrik Egberts; Hodjat Shekarriz; Ulrich R Fölsch; Fred Fändrich; Michael Krawczak; Stefan Schreiber; Jürgen Tepel; Jochen Hampe
Increased heritability of gallstone disease in early onset cases.
Liver international : official journal of the International Association for the Study of the Liver 2008;28(6):895-7.
2008: Espen Melum; Stephan Buch; Clemens Schafmayer; Holger Kalthoff; Jürgen Tepel; Stefan Schreiber; Tom H Karlsen; Jochen Hampe
Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma.
International journal of cancer. Journal international du cancer 2008;123(1):241-2.
2008: Stephan Hellmig; Tobias Bartscht; Wolfgang Fischbach; Ulrich R Fölsch; Stefan Schreiber
Interleukin-10 (-819 C/T) and TNF-A (-308 G/A) as risk factors for H. pylori-associated gastric MALT-lymphoma.
Digestive diseases and sciences 2008;53(7):2007-8.
2008: Mike Ufer; K Dilger; L Leschhorn; Lm Daufresne; I Mosyagin; Philip Rosenstiel; R Haesler; T Kuehbacher; S Nikolaus; Stefan Schreiber; Ingolf Cascorbi
Influence of CYP3A4, CYP3A5, and ABCB1 genotype and expression on budesonide pharmacokinetics: a possible role of intestinal CYP3A4 expression.
Clinical pharmacology and therapeutics 2008;84(1):43-6.
2008: M A Kamm; G R Lichtenstein; W J Sandborn; Stefan Schreiber; K Lees; K Barrett; R Joseph
Randomised trial of once- or twice-daily MMX mesalazine for maintenance of remission in ulcerative colitis.
Gut 2008;57(7):893-902.
2008: Martina E Spehlmann; Alexander Z Begun; Jens Burghardt; Patricia Lepage; Andreas Raedler; Stefan Schreiber
Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study.
Inflammatory bowel diseases 2008;14(7):968-76.
2008: Rajan P Nair; Andreas Ruether; Philip Stuart; Stefan Jenisch; Trilokraj Tejasvi; Ravi Hiremagalore; Stefan Schreiber; Dieter Kabelitz; Henry W Lim; John J Voorhees; Enno Christophers; James T Elder; Michael Weichenthal
Polymorphisms of the IL12B and IL23R genes are associated with psoriasis.
The Journal of investigative dermatology 2008;128(7):1653-61.
2008: Stefan Schreiber; Michael A Kamm; Gary R Lichtenstein
Mesalamine with MMX technology for the treatment of ulcerative colitis.
Expert review of gastroenterology & hepatology 2008;2(3):299-314.
2008: Philip Rosenstiel; Stefan Schreiber
Expression signatures, barriers and beyond: the role of oxidative stress in murine colitis and human inflammatory bowel disease revisited.
European journal of gastroenterology & hepatology 2008;20(6):496-9.
2008: Andre Franke; Tobias Balschun; Tom H Karlsen; Jürgen Hedderich; Sandra May; Timothy Lu; Dörthe Schuldt; Susanna Nikolaus; Philip Rosenstiel; Michael Krawczak; Stefan Schreiber
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.
Nature genetics 2008;40(6):713-5.
2008: M Schürmann; R Kwiatkowski; M Albrecht; A Fischer; Jochen Hampe; Joachim Müller-Quernheim; E Schwinger; Stefan Schreiber
Study of Toll-like receptor gene loci in sarcoidosis.
Clinical and experimental immunology 2008;152(3):423-31.
2008: Delia Lorenz; Frank Papengut; Henrik Frederiksen; Florian Kopper; Stephan Klebe; Kaare Christensen; Stefan Schreiber; Günther Deuschl
Evaluation of a screening instrument for essential tremor.
Movement disorders : official journal of the Movement Disorder Society 2008;23(7):1006-12.
2008: axel walther; Emily Webb; Luis Carvajal Carmona; Peter Broderick; Kimberley Howarth; Alan Pittman; Sarah Spain; Steven Lubbe; Axel Walther; Kate Sullivan; Emma Jaeger; Sarah Fielding; Andrew Rowan; Jayaram Vijayakrishnan; Enric Domingo; Ian Chandler; Zoe Kemp; Mobshra Qureshi; Susan M Farrington; Albert Tenesa; James G D Prendergast; Rebecca A Barnetson; Steven Penegar; Ella Barclay; Wendy Wood; Lynn Martin; Maggie Gorman; Huw Thomas; Julian Peto; Tim BISHOP; Richard Gray; Eamonn R Maher; Anneke Lucassen; David Kerr; D Gareth R Evans; Clemens Schafmayer; Stephan Buch; Henry Völzke; Jochen Hampe; Stefan Schreiber; Ulrich John; Thibaud Koessler; Paul Pharoah; Tom van Wezel; Hans Morreau; Juul Wijnen; John L Hopper; Melissa C Southey; Graham G Giles; Gianluca Severi; Sergi Castellví-Bel; Clara Ruiz-Ponte; Angel Carracedo; Antoni Castells; Asta Försti; Kari Hemminki; Pavel Vodicka; Alessio Naccarati; Lara Lipton; Judy W C Ho; K K Cheng; Pak C Sham; J Luk; Jose A G Agúndez; Jose M Ladero; Miguel de la Hoya; Trinidad Caldés; Iina Niittymäki; Sari Tuupanen; Auli Karhu; Lauri Aaltonen; Jean-Baptiste Cazier; Harry Campbell; Malcolm G Dunlop; Richard S Houlston
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.
Nature genetics 2008;40(5):623-30.
2008: Annegret Fischer; Ruta Valentonyte; Almut Nebel; Michael Nothnagel; Joachim Müller-Quernheim; Manfred Schürmann; Stefan Schreiber
Female-specific association of C-C chemokine receptor 5 gene polymorphisms with Löfgren's syndrome.
Journal of molecular medicine (Berlin, Germany) 2008;86(5):553-61.
2008: Alexander Arlt; Philip Rosenstiel; Marie-Luise Kruse; Frauke Grohmann; Jörg Minkenberg; Neil D Perkins; Ulrich R Fölsch; Stefan Schreiber; Heiner Schäfer
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis.
Biochimica et biophysica acta 2008;1783(5):941-52.
2008: H A Schulze; Robert Häsler; Nancy Mah; Timothy Lu; S Nikolaus; Christine M Costello; Stefan Schreiber
From model cell line to in vivo gene expression: disease-related intestinal gene expression in IBD.
Genes and immunity 2008;9(3):240-8.
2008: Michael Hiller; Karol Szafranski; Rileen Sinha; Klaus Huse; Swetlana Nikolajewa; Philip Rosenstiel; Stefan Schreiber; Rolf Backofen; Matthias Platzer
Assessing the fraction of short-distance tandem splice sites under purifying selection.
RNA (New York, N.Y.) 2008;14(4):616-29.
2008: Philip Rosenstiel; Stefanie Derer; Andreas Till; Robert Häsler; H Eberstein; Burkhard Bewig; S Nikolaus; Almut Nebel; Stefan Schreiber
Systematic expression profiling of innate immune genes defines a complex pattern of immunosenescence in peripheral and intestinal leukocytes.
Genes and immunity 2008;9(2):103-14.
2008: Andreas Till; Philip Rosenstiel; Karen Bräutigam; Christian Sina; Gunnar Jacobs; Hans-Heinrich Oberg; Dirk Seegert; Trinad Chakraborty; Stefan Schreiber
A role for membrane-bound CD147 in NOD2-mediated recognition of bacterial cytoinvasion.
Journal of cell science 2008;121(Pt 4):487-95.
2008: Stephan J Ott; Tanja Kühbacher; Meike Musfeldt; Philip Rosenstiel; Stephan Hellmig; Ateequr Rehman; Oliver Drews; Wilko Weichert; Kenneth N Timmis; Stefan Schreiber
Fungi and inflammatory bowel diseases: Alterations of composition and diversity.
Scandinavian journal of gastroenterology 2008;43(7):831-41.
2008: Klaus Huse; Stefan Taudien; Marco Groth; Philip Rosenstiel; Karol Szafranski; Michael Hiller; Jochen Hampe; Kerstin Junker; Jorg Schubert; Stefan Schreiber; Gerd Birkenmeier; Michael Krawczak; Matthias Platzer
Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2008;29(2):83-92.
2008: Markus Ralser; Almut Nebel; Rabea Kleindorp; Sylvia Krobitsch; Hans Lehrach; Stefan Schreiber; Richard Reinhardt; Bernd Timmermann
Sequencing and genotypic analysis of the triosephosphate isomerase (TPI1) locus in a large sample of long-lived Germans.
BMC genetics 2008;9():38.
2008: Diana Rubin; Ulf Helwig; Michael Nothnagel; Nina Lemke; Stefan Schreiber; Ulrich R Fölsch; Frank Döring; Jürgen Schrezenmeir
Postprandial plasma adiponectin decreases after glucose and high fat meal and is independently associated with postprandial triacylglycerols but not with -- 11388 promoter polymorphism.
The British journal of nutrition 2008;99(1):76-82.
2007: Stephan J Ott; Nour Eddine El Mokhtari; Ateequr Rehman; Philip Rosenstiel; Stephan Hellmig; Tanja Kühbacher; Markus Lins; Rüdiger Simon; Stefan Schreiber
Fungal rDNA signatures in coronary atherosclerotic plaques.
Environmental microbiology 2007;9(12):3035-45.
2007: Inka Lindner; Ulf Helwig; Diana Rubin; Alexandra Fischer; Berit Marten; Stefan Schreiber; Frank Döring; Jürgen Schrezenmeir
Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the metabolic syndrome.
Molecular nutrition & food research 2007;51(12):1447-51.
2007: Susanna Nikolaus; Stefan Schreiber
Diagnostics of inflammatory bowel disease.
Gastroenterology 2007;133(5):1670-89.
2007: Florian Schulz; Ingo Marenholz; Regina Fölster-Holst; Christiane Chen; Alexander Sternjak; Ria Baumgrass; Jorge Esparza-Gordillo; Christoph Grüber; Renate Nickel; Stefan Schreiber; Monika Stoll; Michael Kurek; Franz Rüschendorf; Norbert Hubner; Ulrich Wahn; Young-Ae Lee
A common haplotype of the IL-31 gene influencing gene expression is associated with nonatopic eczema.
The Journal of allergy and clinical immunology 2007;120(5):1097-102.
2007: Kathy King; Richard Bagnall; Sheila A Fisher; Faisal Sheikh; Andrew P Cuthbert; Sipin Tan; Nicholas I Mundy; Philip Rosenstiel; Stefan Schreiber; Christopher G Mathew; Roland Roberts
Identification, evolution, and association study of a novel promoter and first exon of the human NOD2 (CARD15) gene.
Genomics 2007;90(4):493-501.
2007: John V Raelson; Randall Little; Andreas Ruether; Hélène Fournier; Bruno Paquin; Paul Van Eerdewegh; W E C Bradley; Pascal Croteau; Quynh Nguyen-Huu; Jonathan Segal; Sophie Debrus; René Allard; Philip Rosenstiel; Andre Franke; Gunnar Jacobs; Susanna Nikolaus; Jean-Michel Vidal; Peter Szego; Nathalie Laplante; Hilary F Clark; René J Paulussen; John W Hooper; Tim P Keith; Abdelmajid Belouchi; Stefan Schreiber
Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(37):14747-52.
2007: Clemens Schafmayer; Henry Völzke; Stephan Buch; Jan-Hendrik Egberts; Annika Spille; Huberta von Eberstein; Andre Franke; Markus Seeger; Sebastian Hinz; Abdou ElSharawy; Dieter Rosskopf; Mario Brosch; Michael Krawczak; Ulrich R Foelsch; Anton Schafmayer; Frank Lammert; Stefan Schreiber; Fred Faendrich; Jochen Hampe; Juergen Tepel
Investigation of the Lith6 candidate genes APOBEC1 and PPARG in human gallstone disease.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):910-9.
2007: Stephan Buch; Clemens Schafmayer; Henry Völzke; Christian Becker; Andre Franke; Huberta von Eller-Eberstein; Christian Kluck; Ingelore Bässmann; Mario Brosch; Frank Lammert; Juan Miquel; Flavio Nervi; Michael Wittig; Dieter Rosskopf; Birgit Timm; Christine Höll; Markus Seeger; Abdou ElSharawy; Timothy Lu; Jan-Hendrik Egberts; Fred Fändrich; Ulrich R Fölsch; Michael Krawczak; Stefan Schreiber; Peter Nürnberg; Juergen Tepel; Jochen Hampe
A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
Nature genetics 2007;39(8):995-9.
2007: Inke Nitz; Eva Fisher; Cornelia Weikert; Barbara Burwinkel; Yun Li; Matthias Möhlig; Heiner Boeing; Stefan Schreiber; Jürgen Schrezenmeir; Frank Döring
Association analyses of GIP and GIPR polymorphisms with traits of the metabolic syndrome.
Molecular nutrition & food research 2007;51(8):1046-52.
2007: Inke Nitz; Eva Fisher; Harald Grallert; Yun Li; Christian Gieger; Diana Rubin; Heiner Boeing; Joachim Spranger; Inka Lindner; Stefan Schreiber; Wolfgang Rathmann; Henning Gohlke; Angela Döring; H-Erich Wichmann; Jürgen Schrezenmeir; Frank Döring; Thomas Illig
Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations.
The Journal of clinical endocrinology and metabolism 2007;92(8):3183-8.
2007: Clemens Schafmayer; Stephan Buch; Jan-Hendrik Egberts; Andre Franke; Mario Brosch; Abdou El Sharawy; Mareike Conring; Maralde Koschnick; Sven Schwiedernoch; Alexander Katalinic; Bernd Kremer; Ulrich R Fölsch; Michael Krawczak; Fred Fändrich; Stefan Schreiber; Juergen Tepel; Jochen Hampe
Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.
International journal of cancer. Journal international du cancer 2007;121(3):555-8.
2007: Almut Nebel; Peter J P Croucher; Nour Eddine El Mokhtari; Friederike Flachsbart; Stefan Schreiber
Common coding polymorphisms in the ABCA1 gene and risk of early-onset coronary heart disease in northern Germany.
Atherosclerosis 2007;193(2):458-60.
2007: Stefan Schreiber; Mani Khaliq-Kareemi; Ian Craig Lawrance; Ole Østergaard Thomsen; Stephen B Hanauer; Juliet McColm; Ralph Bloomfield; William J Sandborn
Maintenance therapy with certolizumab pegol for Crohn's disease.
The New England journal of medicine 2007;357(3):239-50.
2007: Philip Rosenstiel; Christian Sina; Caroline End; Marcus Renner; Stefan Lyer; Andreas Till; Stephan Hellmig; Susanna Nikolaus; Ulrich R Fölsch; Burkhard Helmke; Frank Autschbach; Peter Schirmacher; Petra Kioschis; Mathias Hafner; Annemarie Poustka; Jan Mollenhauer; Stefan Schreiber
Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(12):8203-11.
2007: Matthias Watzka; Almut Nebel; Nour Eddine El Mokhtari; Boris Ivandic; Jens Müller; Stefan Schreiber; Johannes Oldenburg
Functional promoter polymorphism in the VKORC1 gene is no major genetic determinant for coronary heart disease in Northern Germans.
Thrombosis and haemostasis 2007;97(6):998-1002.
2007: Ulf Helwig; Diana Rubin; Maja Klapper; Yin Li; Michael Nothnagel; Ulrich R Fölsch; Frank Döring; Stefan Schreiber; Jürgen Schrezenmeir
The association of fatty acid-binding protein 2 A54T polymorphism with postprandial lipemia depends on promoter variability.
Metabolism: clinical and experimental 2007;56(6):723-31.
2007: Almut Nebel; Friederike Flachsbart; Arne Schäfer; Michael Nothnagel; Susanna Nikolaus; Nour Eddine El Mokhtari; Stefan Schreiber
Role of the toll-like receptor 4 polymorphism Asp299Gly in longevity and myocardial infarction in German men.
Mechanisms of ageing and development 2007;128(5-6):409-11.
2007: Andre Franke; Philip Rosenstiel; T Balschun; O Von Kampen; Stefan Schreiber; Christian Sina; Jochen Hampe; T H Karlsen; Morten Vatn; Camilla Solberg
No association between the TUCAN (CARD8) Cys10Stop mutation and inflammatory bowel disease in a large retrospective German and a clinically well-characterized Norwegian sample.
Gastroenterology 2007;132(5):2080-1.
2007: Natalie Prescott; Sheila A Fisher; Andre Franke; Jochen Hampe; Clive M Onnie; Dianne Soars; Richard Bagnall; Muddassar M Mirza; Jeremy Sanderson; Alastair Forbes; John C Mansfield; Cathryn M Lewis; Stefan Schreiber; Christopher G Mathew
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5.
Gastroenterology 2007;132(5):1665-71.
2007: Ulf Helwig; Diana Rubin; Julia Kiosz; Stefan Schreiber; Ulrich R Fölsch; Michael Nothnagel; Frank Döring; Jürgen Schrezenmeir
The minor allele of the PPARgamma2 pro12Ala polymorphism is associated with lower postprandial TAG and insulin levels in non-obese healthy men.
The British journal of nutrition 2007;97(5):847-54.
2007: Ulf Helwig; Diana Rubin; J Kiosz; W Bitter; Stefan Schreiber; Frank Döring; Ulrich R Fölsch; Jürgen Schrezenmeir
The effects of retinol on postprandial parameters in men with different FABP2 promoter haplotypes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2007;39(4):237-43.
2007: Philip Rosenstiel; Andreas Till; Stefan Schreiber
NOD-like receptors and human diseases.
Microbes and infection / Institut Pasteur 2007;9(5):648-57.
2007: Alexandra V Pearce; Sheila A Fisher; Natalie Prescott; Clive M Onnie; Reenal Pattni; Peter Green; Alastair Forbes; John Mansfield; Jeremy Sanderson; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Investigation of association of the DLG5 gene with phenotypes of inflammatory bowel disease in the British population.
International journal of colorectal disease 2007;22(4):419-24.
2007: Nadja Bogdanova; Jürgen Horst; Marcin Chlystun; Peter J P Croucher; Almut Nebel; Axel Bohring; Albena Todorova; Stefan Schreiber; Volker Gerke; Michael Krawczak; Arseni Markoff
A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss.
Human molecular genetics 2007;16(5):573-8.
2007: Eva Fisher; Inke Nitz; Inka Lindner; Diana Rubin; Heiner Boeing; Matthias Möhlig; Jochen Hampe; Stefan Schreiber; Jürgen Schrezenmeir; Frank Döring
Candidate gene association study of type 2 diabetes in a nested case-control study of the EPIC-Potsdam cohort - role of fat assimilation.
Molecular nutrition & food research 2007;51(2):185-91.
2007: Jochen Hampe; Andre Franke; Philip Rosenstiel; Andreas Till; Markus Teuber; Klaus Huse; Mario Albrecht; Gabriele Mayr; Francisco M De La Vega; Jason Briggs; Simone Günther; Natalie Prescott; Clive M Onnie; Robert Häsler; Bence Sipos; Ulrich R Fölsch; Thomas Lengauer; Matthias Platzer; Christopher G Mathew; Michael Krawczak; Stefan Schreiber
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.
Nature genetics 2007;39(2):207-11.
2007: Philip Rosenstiel; Klaus Huse; Andre Franke; Jochen Hampe; Kathrin Reichwald; Cornelia Platzer; Roland Roberts; Christopher G Mathew; Matthias Platzer; Stefan Schreiber
Functional characterization of two novel 5' untranslated exons reveals a complex regulation of NOD2 protein expression.
BMC genomics 2007;8():472.
2007: Nour Eddine El Mokhtari; Stephan J Ott; Almut Nebel; Arne Schäfer; Philip Rosenstiel; Matti Förster; Michael Nothnagel; Rüdiger Simon; Stefan Schreiber
Role of NOD2/CARD15 in coronary heart disease.
BMC genetics 2007;8():76.
2007: Thomas Rattei; Stephan Ott; Michaela Gutacker; Jan Rupp; Matthias Maass; Stefan Schreiber; Werner Solbach; Thierry Wirth; Jens Gieffers
Genetic diversity of the obligate intracellular bacterium Chlamydophila pneumoniae by genome-wide analysis of single nucleotide polymorphisms: evidence for highly clonal population structure.
BMC genomics 2007;8():355.
2007: Andreas Wollstein; Alexander Herrmann; Michael Wittig; Michael Nothnagel; Andre Franke; Peter Nürnberg; Stefan Schreiber; Michael Krawczak; Jochen Hampe
Efficacy assessment of SNP sets for genome-wide disease association studies.
Nucleic acids research 2007;35(17):e113.
2007: Andre Franke; Jochen Hampe; Philip Rosenstiel; Christian Becker; Florian Wagner; Robert Häsler; Randall Little; Klaus Huse; Andreas Ruether; Tobias Balschun; Michael Wittig; Abdou ElSharawy; Gabriele Mayr; Mario Albrecht; Natalie Prescott; Clive M Onnie; Hélène Fournier; Tim P Keith; Uwe Radelof; Matthias Platzer; Christopher G Mathew; Monika Stoll; Michael Krawczak; Peter Nürnberg; Stefan Schreiber
Systematic association mapping identifies NELL1 as a novel IBD disease gene.
PloS one 2007;2(8):e691.
2007: Karol Szafranski; Stefanie Schindler; Stefan Taudien; Michael Hiller; Klaus Huse; Niels Jahn; Stefan Schreiber; Rolf Backofen; Matthias Platzer
Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns.
Genome biology 2007;8(8):R154.
2007: Stefan Schreiber; Ali Keshavarzian; Kim L Isaacs; John Schollenberger; Juan P Guzman; Cesare Orlandi; Stephen B Hanauer
A randomized, placebo-controlled, phase II study of tetomilast in active ulcerative colitis.
Gastroenterology 2007;132(1):76-86.
2006: Michael de Vrese; Petra Winkler; Peter Rautenberg; Timm Harder; Christian Noah; Christiane Laue; Stephan Ott; Jochen Hampe; Stefan Schreiber; Knut Heller; Jürgen Schrezenmeir
Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial.
Vaccine 2006;24(44-46):6670-4.
2006: Johannes Zschocke; Almut Nebel; Kate Wicks; Verena Peters; Nour Eddine El Mokhtari; Michael Krawczak; Fokko J van der Woude; Bart Janssen; Stefan Schreiber
Allelic variation in the CNDP1 gene and its lack of association with longevity and coronary heart disease.
Mechanisms of ageing and development 2006;127(11):817-20.
2006: Abdou ElSharawy; Carl Manaster; Markus Teuber; Philip Rosenstiel; Ruta Kwiatkowski; Klaus Huse; Matthias Platzer; Albert Becker; Peter Nürnberg; Stefan Schreiber; Jochen Hampe
SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs.
Human mutation 2006;27(11):1129-34.
2006: Ulf Helwig; Karen Lammers; Fernando Rizzello; Patrizia Brigidi; Verena Rohleder; Elisabetta Caramelli; Paolo Gionchetti; Jürgen Schrezenmeir; Ulrich R Foelsch; Stefan Schreiber; Massimo Campieri
Lactobacilli, bifidobacteria and E. coli nissle induce pro- and anti-inflammatory cytokines in peripheral blood mononuclear cells.
World journal of gastroenterology : WJG 2006;12(37):5978-86.
2006: Matthias Platzer; Michael Hiller; Karol Szafranski; Niels Jahn; Jochen Hampe; Stefan Schreiber; Rolf Backofen; Klaus Huse
Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?
Nature biotechnology 2006;24(9):1068-70.
2006: Clemens Schafmayer; Juergen Tepel; Andre Franke; Stephan Buch; Sören Lieb; Markus Seeger; Frank Lammert; Bernd Kremer; Ulrich R Fölsch; Fred Fändrich; Stefan Schreiber; Jochen Hampe
Investigation of the Lith1 candidate genes ABCB11 and LXRA in human gallstone disease.
Hepatology (Baltimore, Md.) 2006;44(3):650-7.
2006: Stefan Gottschlich; Petra Ambrosch; Christian Cordes; Tibor Görögh; Stefan Schreiber; Robert Häsler
Gene expression profiling of head and neck squamous cell carcinoma using cDNA microarrays.
International journal of oncology 2006;29(3):605-13.
2006: Nour Eddine El Mokhtari; Stephan J Ott; Almut Nebel; Rüdiger Simon; Stefan Schreiber
A functional variant in the CARD4 gene and risk of premature coronary heart disease.
International journal of immunogenetics 2006;33(4):307-11.
2006: Brigitte K Flesch; S Nikolaus; Nour Eddine El Mokhtari; Stefan Schreiber; Almut Nebel
The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.
International journal of immunogenetics 2006;33(4):277-9.
2006: Sheila A Fisher; Jochen Hampe; Clive M Onnie; Mark J Daly; Christine R Curley; Shaun Purcell; Jeremy Sanderson; John Mansfield; Vito Annese; Alastair Forbes; Cathryn M Lewis; Stefan Schreiber; John D Rioux; Christopher G Mathew
Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.
Human mutation 2006;27(8):778-85.
2006: Stephan Hellmig; Frank Gieseler; Stephan Ott; Philip Rosenstiel; Wolfgang Fischbach; Ulrich R Fölsch; Stefan Schreiber
Germline variations of the topoisomerase IIalpha gene as risk factors for primary gastric B-cell lymphoma.
Cancer letters 2006;238(2):295-303.
2006: Birte Grössner-Schreiber; Thomas Fetter; Jürgen Hedderich; Thomas Kocher; Stefan Schreiber; Søren Jepsen
Prevalence of dental caries and periodontal disease in patients with inflammatory bowel disease: a case-control study.
Journal of clinical periodontology 2006;33(7):478-84.
2006: Philip Rosenstiel; Stephan Hellmig; Jochen Hampe; Stephan Ott; Andreas Till; Wolfgang Fischbach; Hany Sahly; Ralph Lucius; Ulrich R Fölsch; Dana Philpott; Stefan Schreiber
Influence of polymorphisms in the NOD1/CARD4 and NOD2/CARD15 genes on the clinical outcome of Helicobacter pylori infection.
Cellular microbiology 2006;8(7):1188-98.
2006: Andre Franke; Andreas Wollstein; Markus Teuber; Michael Wittig; Timothy Lu; Katrin Hoffmann; Peter Nürnberg; Michael Krawczak; Stefan Schreiber; Jochen Hampe
GENOMIZER: an integrated analysis system for genome-wide association data.
Human mutation 2006;27(6):583-8.
2006: Marcela Karey Tello-Ruiz; Christine R Curley; Terrye Delmonte; Cosmas Giallourakis; Andrew Kirby; Kathryn Miller; Gary Wild; Albert Cohen; Diane Langelier; Anna Latiano; Neils Wedemeyer; Eric S Lander; Stefan Schreiber; Vito Annese; Mark J Daly; John D Rioux
Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19.
European journal of human genetics : EJHG 2006;14(6):780-90.
2006: Tanja Kühbacher; Stephan J Ott; Ulf Helwig; T Mimura; Fernando Rizzello; Brigitta Kleessen; Paolo Gionchetti; Michael Blaut; Massimo Campieri; Ulrich R Fölsch; M A Kamm; Stefan Schreiber
Bacterial and fungal microbiota in relation to probiotic therapy (VSL#3) in pouchitis.
Gut 2006;55(6):833-41.
2006: Y Li; Eva Fisher; Maja Klapper; Heiner Boeing; A Pfeiffer; Jochen Hampe; Stefan Schreiber; Barbara Burwinkel; Jürgen Schrezenmeir; Frank Döring
Association between functional FABP2 promoter haplotype and type 2 diabetes.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2006;38(5):300-7.
2006: Valentina Medici; Silvia Mascheretti; Peter J P Croucher; Monika Stoll; Jochen Hampe; Jochen Grebe; Giacomo Carlo Sturniolo; Camilla Solberg; Jørgen Jahnsen; Bjørn Moum; Stefan Schreiber; Morten Vatn
Extreme heterogeneity in CARD15 and DLG5 Crohn disease-associated polymorphisms between German and Norwegian populations.
European journal of human genetics : EJHG 2006;14(4):459-68.
2006: Tim Becker; Ruta Valentonyte; Peter J P Croucher; Konstantin Strauch; Stefan Schreiber; Jochen Hampe; Michael Knapp
Identification of probable genotyping errors by consideration of haplotypes.
European journal of human genetics : EJHG 2006;14(4):450-8.
2006: Stefan Schreiber; Brian G Feagan; Geert D'Haens; Jean-Frédéric Colombel; Karel Geboes; Mikhail Yurcov; Vasily Isakov; Oleg Golovenko; Charles N Bernstein; Diether Ludwig; Trevor Winter; Ulrich Meier; Chan Yong; Jürgen Steffgen
Oral p38 mitogen-activated protein kinase inhibition with BIRB 796 for active Crohn's disease: a randomized, double-blind, placebo-controlled trial.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2006;4(3):325-34.
2006: Inka Lindner; Diana Rubin; Ulf Helwig; Inke Nitz; Jochen Hampe; Stefan Schreiber; Jürgen Schrezenmeir; Frank Döring
The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.
Molecular nutrition & food research 2006;50(3):270-4.
2006: Stefan Jenisch; Jochen Hampe; James T Elder; Rajan P Nair; Philip Stuart; John J Voorhees; Stefan Schreiber; Dieter Kabelitz; Enno Christophers; Michael Weichenthal
CARD15 mutations in patients with plaque-type psoriasis and psoriatic arthritis: lack of association.
Archives of dermatological research 2006;297(9):409-11.
2006: Philip Rosenstiel; Klaus Huse; Andreas Till; Jochen Hampe; Stephan Hellmig; Christian Sina; Susanne Billmann; Oliver von Kampen; Georg H Waetzig; Matthias Platzer; Dirk Seegert; Stefan Schreiber
A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(9):3280-5.
2006: Stephan J Ott; Nour Eddine El Mokhtari; Meike Musfeldt; Stephan Hellmig; Sandra Freitag; Ateequr Rehman; Tanja Kühbacher; Susanna Nikolaus; Pawel Namsolleck; Michael Blaut; Jochen Hampe; Hany Sahly; Alexander Reinecke; Nils Haake; Rainer Günther; Dietmar Krüger; Markus Lins; Gunhild Herrmann; Ulrich R Fölsch; Rüdiger Simon; Stefan Schreiber
Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease.
Circulation 2006;113(7):929-37.
2006: Christian Sina; Stefan Schreiber; Jörg C Hoffmann; Gerhard Rogler; Jürgen Schölmerich; Martin Zeitz; Ulrich R Fölsch
[The German competence network inflammatory bowel disease (KNCED) -- network research leads to the identification of the cause of disease and to the improvement in patient care].
Medizinische Klinik (Munich, Germany : 1983) 2006;101(2):161-5.
2006: Michael Hiller; Klaus Huse; Karol Szafranski; Niels Jahn; Jochen Hampe; Stefan Schreiber; Rolf Backofen; Matthias Platzer
Single-nucleotide polymorphisms in NAGNAG acceptors are highly predictive for variations of alternative splicing.
American journal of human genetics 2006;78(2):291-302.
2006: Dieter Weichart; Johan Gobom; Sina Klopfleisch; Robert Häsler; Niklas Gustavsson; Susanne Billmann; Hans Lehrach; Dirk Seegert; Stefan Schreiber; Philip Rosenstiel
Analysis of NOD2-mediated proteome response to muramyl dipeptide in HEK293 cells.
The Journal of biological chemistry 2006;281(4):2380-9.
2006: Clemens Schafmayer; Jürgen Hartleb; Juergen Tepel; Stefan Albers; Sandra Freitag; Henry Völzke; Stephan Buch; Markus Seeger; Birgit Timm; Bernd Kremer; Ulrich R Fölsch; Fred Fändrich; Michael Krawczak; Stefan Schreiber; Jochen Hampe
Predictors of gallstone composition in 1025 symptomatic gallstones from Northern Germany.
BMC gastroenterology 2006;6():36.
2006: Michael Steffens; Claudia Lamina; Thomas Illig; Thomas Bettecken; Rainer Vogler; Patricia Entz; Eun-Kyung Suk; Mohammad R Toliat; Norman Klopp; Almuth Caliebe; Inke R König; Karola Köhler; Jan Ludemann; Amalia Diaz-Lacava; Rolf Fimmers; Peter Lichtner; Andreas Ziegler; Andreas Wolf; Michael Krawczak; Peter Nūrnberg; Jochen Hampe; Stefan Schreiber; Thomas Meitinger; H-Erich Wichmann; Kathryn Roeder; Thomas F Wienker; Max P Baur
SNP-based analysis of genetic substructure in the German population.
Human heredity 2006;62(1):20-9.
2006: Michael Hiller; Klaus Huse; Karol Szafranski; Philip Rosenstiel; Stefan Schreiber; Rolf Backofen; Matthias Platzer
Phylogenetically widespread alternative splicing at unusual GYNGYN donors.
Genome biology 2006;7(7):R65.
2006: Diana Rubin; Ulf Helwig; Maria Pfeuffer; Stefan Schreiber; Heiner Boeing; Eva Fisher; Andreas Pfeiffer; Sandra Freitag-Wolf; Ulrich R Foelsch; Frank Doering; Jürgen Schrezenmeir
A common functional exon polymorphism in the microsomal triglyceride transfer protein gene is associated with type 2 diabetes, impaired glucose metabolism and insulin levels.
Journal of human genetics 2006;51(6):567-74.
2006: Michael Krawczak; Susanna Nikolaus; Huberta von Eberstein; Peter J P Croucher; Nour Eddine El Mokhtari; Stefan Schreiber
PopGen: population-based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships.
Community genetics 2006;9(1):55-61.
2006: Stephan Hellmig; Stephan Ott; Philip Rosenstiel; Ulrich Robert Fölsch; Jochen Hampe; Stefan Schreiber
Genetic variants in matrix metalloproteinase genes are associated with development of gastric ulcer in H. Pylori infection.
The American journal of gastroenterology 2006;101(1):29-35.
2006: Friederike Flachsbart; Peter J P Croucher; Susanna Nikolaus; Jochen Hampe; Christina Cordes; Stefan Schreiber; Almut Nebel
Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity.
Experimental gerontology 2006;41(1):98-102.
2006: Weiyue Zheng; Philip Rosenstiel; Klaus Huse; Christian Sina; Ruta Valentonyte; Nancy Mah; Lutz Zeitlmann; Johannes Grosse; N Ruf; Peter Nürnberg; Christine M Costello; Clive M Onnie; Christopher G Mathew; Matthias Platzer; Stefan Schreiber; Jochen Hampe
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.
Genes and immunity 2006;7(1):11-8.
2005: Stephan Hellmig; Wolfgang Fischbach; Maria-Elisabeth Goebeler-Kolve; Ulrich R Fölsch; Jochen Hampe; Stefan Schreiber
A functional promotor polymorphism of TNF-alpha is associated with primary gastric B-Cell lymphoma.
The American journal of gastroenterology 2005;100(12):2644-9.
2005: Friederike Flachsbart; Almut Nebel; Susanna Nikolaus; Stefan Schreiber
[Genetic factors in longevity. Healthy living into old age--what role do genes play?].
Medizinische Monatsschrift für Pharmazeuten 2005;28(12):437-42.
2005: Inka Lindner; Ulf Helwig; Diana Rubin; Yun Li; Eva Fisher; Heiner Boeing; Matthias Möhlig; Joachim Spranger; Andreas Pfeiffer; Jochen Hampe; Stefan Schreiber; Frank Döring; Jürgen Schrezenmeir
Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations.
Molecular nutrition & food research 2005;49(10):972-6.
2005: Stephan Hellmig; Andrea Titz; Stefanie Steinel; Stephan Ott; Ulrich R Fölsch; Jochen Hampe; Stefan Schreiber
Influence of IL-1 gene cluster polymorphisms on the development of H. pylori associated gastric ulcer.
Immunology letters 2005;100(2):107-12.
2005: Stefan Schreiber; Paul Rutgeerts; Richard N Fedorak; Munaa Khaliq-Kareemi; Michael A Kamm; Michel Boivin; Charles N Bernstein; Michael Staun; Ole Østergaard Thomsen; Alison Innes
A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease.
Gastroenterology 2005;129(3):807-18.
2005: Christine M Costello; Nancy Mah; Robert Häsler; Philip Rosenstiel; Georg H Waetzig; Andreas Hahn; Timothy Lu; Yesim Gurbuz; Susanna Nikolaus; Mario Albrecht; Jochen Hampe; Ralph Lucius; Günther Klöppel; Holger Eickhoff; Hans Lehrach; Thomas Lengauer; Stefan Schreiber
Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays.
PLoS medicine 2005;2(8):e199.
2005: Stephan Hellmig; Stephan Ott; Meike Musfeldt; Markus Kosmahl; Philip Rosenstiel; Eckhard Stüber; Jochen Hampe; Ulrich R Fölsch; Stefan Schreiber
Life-threatening chronic enteritis due to colonization of the small bowel with Stenotrophomonas maltophilia.
Gastroenterology 2005;129(2):706-12.
2005: Michael de Vrese; Petra Winkler; Peter Rautenberg; Timm Harder; Christian Noah; Christiane Laue; Stephan Ott; Jochen Hampe; Stefan Schreiber; Knut Heller; Jürgen Schrezenmeir
Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial.
Clinical nutrition (Edinburgh, Scotland) 2005;24(4):481-91.
2005: Almut Nebel; Stefan Schreiber
Allelic variation and human longevity.
Science of aging knowledge environment : SAGE KE 2005;2005(29):pe23.
2005: Stephan Hellmig; Markus Seeger; Eckhard Stüber; Karlheinz Kiehne; Stefan Schreiber; Ulrich R Fölsch
Endoscopic-guided capsule endoscopy in a patient with small-bowel varices after Whipple's operation.
Gastrointestinal endoscopy 2005;62(1):166-9.
2005: Carl Manaster; Weiyue Zheng; Markus Teuber; Stefan Wächter; Frank Döring; Stefan Schreiber; Jochen Hampe
InSNP: a tool for automated detection and visualization of SNPs and InDels.
Human mutation 2005;26(1):11-9.
2005: Axel M Hillmer; Sandra Hanneken; Sibylle Ritzmann; Tim Becker; Jan Freudenberg; Felix F Brockschmidt; Antonia Flaquer; Yun Freudenberg-Hua; Rami Abou Jamra; Christine Metzen; Uwe Heyn; Nadine Schweiger; Regina C Betz; Bettina Blaumeiser; Jochen Hampe; Stefan Schreiber; Thomas G. Schulze; Hans Christian Hennies; Johannes Schumacher; Peter Propping; Thomas Ruzicka; Sven Cichon; Thomas F Wienker; Roland Kruse; Markus M Nothen
Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia.
American journal of human genetics 2005;77(1):140-8.
2005: Stephan Hellmig; Wolfgang Fischbach; Maria-Elisabeth Goebeler-Kolve; Ulrich R Fölsch; Jochen Hampe; Stefan Schreiber
Association study of a functional Toll-like receptor 4 polymorphism with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma.
Leukemia & lymphoma 2005;46(6):869-72.
2005: Eugen Musch; Tilo Andus; Wolfgang Kruis; Andreas Raedler; Martina Spehlmann; Stefan Schreiber; Bernd Krakamp; Mouhamad Malek; Helmut Malchow; Filip Zavada; Gerhard Engelberg Feurle
Interferon-beta-1a for the treatment of steroid-refractory ulcerative colitis: a randomized, double-blind, placebo-controlled trial.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(6):581-6.
2005: Almut Nebel; Peter J P Croucher; Rieke Stiegeler; Susanna Nikolaus; Michael Krawczak; Stefan Schreiber
No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(22):7906-9.
2005: Ruta Valentonyte; Jochen Hampe; Peter J P Croucher; Joachim Müller-Quernheim; Eberhard Schwinger; Stefan Schreiber; Manfred Schürmann
Study of C-C chemokine receptor 2 alleles in sarcoidosis, with emphasis on family-based analysis.
American journal of respiratory and critical care medicine 2005;171(10):1136-41.
2005: Stefan Schreiber; Philip Rosenstiel; Mario Albrecht; Jochen Hampe; Michael Krawczak
Genetics of Crohn disease, an archetypal inflammatory barrier disease.
Nature reviews. Genetics 2005;6(5):376-88.
2005: Carl Manaster; Ruta Valentonyte; Markus Teuber; Weiyue Zheng; Stefan Schreiber; Jochen Hampe
SGCaller: a program to call and review genotypes measured by sequencing.
BioTechniques 2005;38(4):544, 546.
2005: Stefan Schreiber
The complicated path to true causes of disease: role of nuclear factor kappaB in inflammatory bowel disease.
Gut 2005;54(4):444-5.
2005: Ruta Valentonyte; Jochen Hampe; Klaus Huse; Philip Rosenstiel; Mario Albrecht; Annette Stenzel; Marion Nagy; Karoline Gaede; Andre Franke; Robert Haesler; Andreas Koch; Thomas Lengauer; Dirk Seegert; Norbert Reiling; Stefan Ehlers; Eberhard Schwinger; Matthias Platzer; Michael Krawczak; Joachim Müller-Quernheim; Manfred Schürmann; Stefan Schreiber
Sarcoidosis is associated with a truncating splice site mutation in BTNL2.
Nature genetics 2005;37(4):357-64.
2005: Stephan Hellmig; Silvia Mascheretti; Ulrich R Fölsch; Stefan Schreiber
Functional promotor polymorphism in RANTES gene does not influence the clinical course of Helicobacter pylori infection.
Journal of gastroenterology and hepatology 2005;20(3):405-8.
2005: Stephan Hellmig; Silvia Mascheretti; J Renz; Henning Frenzel; F Jelschen; J K Rehbein; Ulrich R Fölsch; Jochen Hampe; Stefan Schreiber
Haplotype analysis of the CD11 gene cluster in patients with chronic Helicobacter pylori infection and gastric ulcer disease.
Tissue antigens 2005;65(3):271-4.
2005: Andreas Till; Philip Rosenstiel; Anja Krippner-Heidenreich; Silvia Mascheretti-Croucher; Peter J P Croucher; Heiner Schäfer; Peter Scheurich; Dirk Seegert; Stefan Schreiber
The Met-196 -> Arg variation of human tumor necrosis factor receptor 2 (TNFR2) affects TNF-alpha-induced apoptosis by impaired NF-kappaB signaling and target gene expression.
The Journal of biological chemistry 2005;280(7):5994-6004.
2005: Philip Rosenstiel; Jørgen Agnholt; Jens Kelsen; Valentina Medici; Georg H Waetzig; Dirk Seegert; Stefan Schreiber
Differential modulation of p38 mitogen activated protein kinase and STAT3 signalling pathways by infliximab and etanercept in intestinal T cells from patients with Crohn's disease.
Gut 2005;54(2):314-5; author reply 316-6.
2005: Timothy Lu; Christine M Costello; Peter J P Croucher; Robert Häsler; Günther Deuschl; Stefan Schreiber
Can Zipf's law be adapted to normalize microarrays?
BMC bioinformatics 2005;6():37.
2005: Georg H Waetzig; Philip Rosenstiel; Alexander Arlt; Andreas Till; Karen Bräutigam; Heiner Schäfer; Stefan Rose-John; Dirk Seegert; Stefan Schreiber
Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(1):91-3.
2004: Stephan J Ott; Meike Musfeldt; Kenneth N Timmis; Jochen Hampe; Dirk F Wenderoth; Stefan Schreiber
In vitro alterations of intestinal bacterial microbiota in fecal samples during storage.
Diagnostic microbiology and infectious disease 2004;50(4):237-45.
2004: Michael Hiller; Klaus Huse; Karol Szafranski; Niels Jahn; Jochen Hampe; Stefan Schreiber; Rolf Backofen; Matthias Platzer
Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity.
Nature genetics 2004;36(12):1255-7.
2004: Stephan Hellmig; Steffen Vollenberg; Maria-Elisabeth Goebeler-Kolve; Wolfgang Fischbach; Jochen Hampe; Ulrich R Fölsch; Stefan Schreiber
IL-1 gene cluster polymorphisms and development of primary gastric B-cell lymphoma in Helicobacter pylori infection.
Blood 2004;104(9):2994-5.
2004: Stefan Schreiber; J Hanpe; Susanna Nikolaus; Ulrich R Foelsch
Review article: exploration of the genetic aetiology of inflammatory bowel disease--implications for diagnosis and therapy.
Alimentary pharmacology & therapeutics 2004;20 Suppl 4():1-8.
2004: Tanja Kühbacher; Stefan Schreiber; Ulrich R Fölsch
Ulcerative colitis: conservative management and long-term effects.
Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie 2004;389(5):350-3.
2004: Silvia Mascheretti; Stefan Schreiber
The role of pharmacogenomics in the prediction of efficacy of anti-TNF therapy in patients with Crohn's disease.
Pharmacogenomics 2004;5(5):479-86.
2004: Stephan J Ott; Meike Musfeldt; Uwe Ullmann; Jochen Hampe; Stefan Schreiber
Quantification of intestinal bacterial populations by real-time PCR with a universal primer set and minor groove binder probes: a global approach to the enteric flora.
Journal of clinical microbiology 2004;42(6):2566-72.
2004: Silvia Mascheretti; Peter J P Croucher; Stefan Schreiber
Pharmacogenetics of inflammatory bowel disease.
Best practice & research. Clinical gastroenterology 2004;18(3):597-609.
2004: Almut Nebel; Stefan Schreiber
GEHA--the pan-European "Genetics of Healthy Aging" project.
Science of aging knowledge environment : SAGE KE 2004;2004(21):pe23.
2004: Monika Stoll; Brit Corneliussen; Christine M Costello; Georg H Waetzig; Bjorn Mellgard; W Andreas Koch; Philip Rosenstiel; Mario Albrecht; Peter J P Croucher; Dirk Seegert; Susanna Nikolaus; Jochen Hampe; Thomas Lengauer; Stefan Pierrou; Ulrich R Foelsch; Christopher G Mathew; Maria Lagerstrom-Fermer; Stefan Schreiber
Genetic variation in DLG5 is associated with inflammatory bowel disease.
Nature genetics 2004;36(5):476-80.
2004: Silvia Mascheretti; Holger Hinrichsen; S Ross; Peter Buggisch; Jochen Hampe; Ulrich R Foelsch; Stefan Schreiber
Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients.
Clinical and experimental immunology 2004;136(2):328-33.
2004: Stephan J Ott; Meike Musfeldt; D F Wenderoth; Jochen Hampe; O Brant; Ulrich R Fölsch; K N Timmis; Stefan Schreiber
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease.
Gut 2004;53(5):685-93.
2004: Ulrich R Fölsch; Stefan Schreiber
[Competence networks in internal medicine].
Der Internist 2004;45(4):383.
2004: Volker Kahlke; Clemens Schafmayer; Bodo Schniewind; Dirk Seegert; Stefan Schreiber; Jörg Schröder
Are postoperative complications genetically determined by TNF-beta NcoI gene polymorphism?
Surgery 2004;135(4):365-73; discussion 374-5.
2004: Ulrich R Fölsch; Jochen Grebe; Stefan Schreiber
[Chronic inflammatory bowel diseases competence network ].
Der Internist 2004;45(4):402-8.
2004: Annette Stenzel; Timothy Lu; W Andreas Koch; Jochen Hampe; Simone M Guenther; Francisco M De La Vega; Michael Krawczak; Stefan Schreiber
Patterns of linkage disequilibrium in the MHC region on human chromosome 6p.
Human genetics 2004;114(4):377-85.
2004: Ulf Helwig; Paolo Gionchetti; Fernando Rizzello; Karen Lammers; Tanja Kühbacher; Stefan Schreiber; Marco Baggiolini; Mariagrazia Uguccioni; Massimo Campieri
CXC and CC chemokine expression in inflamed and noninflamed pelvic ileal pouch tissue.
International journal of colorectal disease 2004;19(2):165-70.
2004: Nancy Mah; Anders Thelin; Timothy Lu; Susanna Nikolaus; Tanja Kühbacher; Yesim Gurbuz; Holger Eickhoff; Günther Klöppel; Hans Lehrach; Björn Mellgård; Christine M Costello; Stefan Schreiber
A comparison of oligonucleotide and cDNA-based microarray systems.
Physiological genomics 2004;16(3):361-70.
2004: Jochen Hampe; Ruta Valentonyte; Carl Manaster; Markus Teuber; Stefan Jenisch; Patricia Entz; Marion Nagy; Stefan Schreiber
Nonelectrophoretic method for high-throughput HLA-DRB1 group genotyping.
BioTechniques 2004;36(1):148-51.
2003: Peter J P Croucher; Silvia Mascheretti; Ulrich R Foelsch; Jochen Hampe; Stefan Schreiber
Lack of association between the C3435T MDR1 gene polymorphism and inflammatory bowel disease in two independent Northern European populations.
Gastroenterology 2003;125(6):1919-20; author reply 1920-1.
2003: Jochen Hampe; Stefan Schreiber; Michael Krawczak
Entropy-based SNP selection for genetic association studies.
Human genetics 2003;114(1):36-43.
2003: Mario Albrecht; Thomas Lengauer; Stefan Schreiber
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence.
Bioinformatics (Oxford, England) 2003;19(17):2171-5.
2003: Mario Albrecht; Francisco S Domingues; Stefan Schreiber; Thomas Lengauer
Structural localization of disease-associated sequence variations in the NACHT and LRR domains of PYPAF1 and NOD2.
FEBS letters 2003;554(3):520-8.
2003: M Schürmann; Ruta Valentonyte; Jochen Hampe; Joachim Müller-Quernheim; E Schwinger; Stefan Schreiber
CARD15 gene mutations in sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;22(5):748-54.
2003: Sarah H Shaw; Jochen Hampe; Raymond White; Christopher G Mathew; Mark E Curran; Stefan Schreiber
Stratification by CARD15 variant genotype in a genome-wide search for inflammatory bowel disease susceptibility loci.
Human genetics 2003;113(6):514-21.
2003: Sheila A Fisher; A Moody; Muddassar M Mirza; Andrew P Cuthbert; Jochen Hampe; A Macpherson; Jeremy Sanderson; Alastair Forbes; John Mansfield; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Genetic variation at the chromosome 16 chemokine gene cluster: development of a strategy for association studies in complex disease.
Annals of human genetics 2003;67(Pt 5):377-90.
2003: Susanna Nikolaus; Paul Rutgeerts; R Fedorak; A Hillary Steinhart; Gary E Wild; D Theuer; J Möhrle; Stefan Schreiber
Interferon beta-1a in ulcerative colitis: a placebo controlled, randomised, dose escalating study.
Gut 2003;52(9):1286-90.
2003: Georg H Waetzig; Philip Rosenstiel; Susanna Nikolaus; Dirk Seegert; Stefan Schreiber
Differential p38 mitogen-activated protein kinase target phosphorylation in responders and nonresponders to infliximab.
Gastroenterology 2003;125(2):633-4; author reply 635-6.
2003: Cosmas Giallourakis; Monika Stoll; Katie Miller; Jochen Hampe; Eric S Lander; Mark J Daly; Stefan Schreiber; John D Rioux
IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis.
American journal of human genetics 2003;73(1):205-11.
2003: Kathy King; A Moody; Sheila A Fisher; Muddassar M Mirza; Andrew P Cuthbert; Jochen Hampe; A Sutherland-Craggs; Jeremy Sanderson; Andrew J S Macpherson; Alastair Forbes; John Mansfield; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Genetic variation in the IGSF6 gene and lack of association with inflammatory bowel disease.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003;30(3):187-90.
2003: Nicole Herbon; Monika Werner; Christine Braig; Henning Gohlke; Gaby Dütsch; Thomas Illig; Janine Altmüller; Jochen Hampe; Annette Lantermann; Stefan Schreiber; Ezio Bonifacio; Annette Ziegler; Sibylle Schwab; Dieter B Wildenauer; Dirk van den Boom; Andreas Braun; Michael Knapp; Peter Reitmeir; Matthias Wjst
High-resolution SNP scan of chromosome 6p21 in pooled samples from patients with complex diseases.
Genomics 2003;81(5):510-8.
2003: Philip Rosenstiel; Massimo Fantini; Karen Bräutigam; Tanja Kühbacher; Georg H Waetzig; Dirk Seegert; Stefan Schreiber
TNF-alpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells.
Gastroenterology 2003;124(4):1001-9.
2003: Muddassar M Mirza; Sheila A Fisher; Kathy King; Andrew P Cuthbert; Jochen Hampe; Jeremy Sanderson; John Mansfield; Peter Donaldson; Andrew J S Macpherson; Alastair Forbes; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease.
American journal of human genetics 2003;72(4):1018-22.
2003: Mario Albrecht; Francisco S Domingues; Stefan Schreiber; Thomas Lengauer
Identification of mammalian orthologs associates PYPAF5 with distinct functional roles.
FEBS letters 2003;538(1-3):173-7.
2003: Peter J P Croucher; Silvia Mascheretti; Jochen Hampe; Klaus Huse; Henning Frenzel; Monika Stoll; Timothy Lu; Susanna Nikolaus; Suk-Kyun Yang; Michael Krawczak; Won Ho Kim; Stefan Schreiber
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.
European journal of human genetics : EJHG 2003;11(1):6-16.
2002: Ulrich R Fölsch; J Hoffmann; W Höhne; Karl-Heinz Janke; Bodo Klump; G Rogler; Stefan Schreiber
[Chronic inflammatory bowel diseases competence network. Results and significance for general practice].
Der Internist 2002;43(11):1419-29.
2002: Stefan Schreiber; Jochen Hampe; Jochen Grebe; Susanna Nikolaus; Monika Stoll; Ulrich R Fölsch
[Genetics and the environment. Has the picture become clearer?].
Der Internist 2002;43(11):1335-41.
2002: Silvia Mascheretti; Jochen Hampe; Peter J P Croucher; Susanna Nikolaus; Tilo Andus; Silvia Schubert; Allan Olson; Weihang Bao; Ulrich R Fölsch; Stefan Schreiber
Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials.
Pharmacogenetics 2002;12(7):509-15.
2002: A Rohr; D Rohr; Tanja Kühbacher; Stefan Schreiber; Martin Heller; Michael Reuter
[Radiological assessment of small bowel obstructions: Value of conventional enteroclysis and dynamic MR-enteroclysis].
RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin 2002;174(9):1158-64.
2002: Stefan Schreiber; Philip Rosenstiel; Jochen Hampe; Susanna Nikolaus; B Groessner; Arndt Schottelius; Tanja Kühbacher; J Hämling; Ulrich R Fölsch; Dirk Seegert
Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease.
Gut 2002;51(3):379-85.
2002: Volker Kahlke; Christoph Dohm; Torge Mees; Kerstin Brötzmann; Stefan Schreiber; Jörg Schröder
Early interleukin-10 treatment improves survival and enhances immune function only in males after hemorrhage and subsequent sepsis.
Shock (Augusta, Ga.) 2002;18(1):24-8.
2002: Annette Lantermann; Jochen Hampe; Won H Kim; Trevor A Winter; Mark Kidd; Marion Nagy; Ulrich R Fölsch; Stefan Schreiber
Investigation of HLA-DPA1 genotypes as predictors of inflammatory bowel disease in the German, South African, and South Korean populations.
International journal of colorectal disease 2002;17(4):238-44.
2002: K Geschonke; M Klempt; N Lynch; Stefan Schreiber; S Fenselau; Jürgen Schrezenmeir
Detection of a promoter polymorphism in the gene of intestinal fatty acid binding protein (I-FABP).
Annals of the New York Academy of Sciences 2002;967():548-53.
2002: Georg H Waetzig; Dirk Seegert; Philip Rosenstiel; Susanna Nikolaus; Stefan Schreiber
p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5342-51.
2002: Jochen Hampe; Jochen Grebe; Susanna Nikolaus; Camilla Solberg; Peter J P Croucher; Silvia Mascheretti; Jørgen Jahnsen; Bjørn Moum; Bodo Klump; Michael Krawczak; Muddassar M Mirza; Ulrich R Foelsch; Morten Vatn; Stefan Schreiber
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study.
Lancet 2002;359(9318):1661-5.
2002: Stephan Hellmig; Eckhard Stüber; C Schulte; Stavros Katsoulis; Stefan Schreiber; Ulrich R Fölsch
[Recurrent sanguineous and mucous diarrhea and spasms in a 46-year-old woman--manifestation of endometriosis in the colon sigmoideum].
Zeitschrift für Gastroenterologie 2002;40(5):291-4.
2002: Dirk Seegert; Stefan Schreiber
Overview: interleukin-16 and its role in inflammatory bowel disease.
Current opinion in investigational drugs (London, England : 2000) 2002;3(4):562-4.
2002: Sheila A Fisher; Jochen Hampe; Andrew J S Macpherson; Alastair Forbes; John E Lennard-Jones; Stefan Schreiber; Mark E Curran; Christopher G Mathew; Cathryn M Lewis
Sex stratification of an inflammatory bowel disease genome search shows male-specific linkage to the HLA region of chromosome 6.
European journal of human genetics : EJHG 2002;10(4):259-65.
2002: Andrew P Cuthbert; Sheila A Fisher; Muddassar M Mirza; Kathy King; Jochen Hampe; Peter J P Croucher; Silvia Mascheretti; Jeremy Sanderson; Alastair Forbes; John Mansfield; Stefan Schreiber; Cathryn M Lewis; Christopher G Mathew
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease.
Gastroenterology 2002;122(4):867-74.
2002: Henning Frenzel; Jochen Hampe; Klaus Huse; Silvia Mascheretti; Peter P Croucher; Nicholas J Lynch; Reiner Siebert; Matthias Platzer; Stefan Schreiber
Mutation detection and physical mapping of the CD11 gene cluster in association with inflammatory bowel disease.
Immunogenetics 2002;53(10-11):835-42.
2002: Jochen Hampe; Henning Frenzel; Muddassar M Mirza; Peter J P Croucher; Andrew P Cuthbert; Silvia Mascheretti; Klaus Huse; Matthias Platzer; Stephen Bridger; Birgit Meyer; Peter Nürnberg; Pieter C F Stokkers; Michael Krawczak; Christopher G Mathew; Mark Curran; Stefan Schreiber
Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):321-6.
2002: Stefan Schreiber; Christine M Costello
Pharmacogenomics in gastrointestinal disorders.
The European journal of surgery. Supplement. : = Acta chirurgica. Supplement 2002;(587):70-6.
2002: Silvia Mascheretti; Jochen Hampe; Tanja Kühbacher; Hans Herfarth; Michael Krawczak; Ulrich R Fölsch; Stefan Schreiber
Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab.
The pharmacogenomics journal 2002;2(2):127-36.
2002: Alexander Swidsinski; Axel Ladhoff; Annelie Pernthaler; Sonja Swidsinski; Vera Loening-Baucke; Maria-Anna Ortner; Jutta Weber; Uwe Hoffmann; Stefan Schreiber; Manfred Dietel; Herbert Lochs
Mucosal flora in inflammatory bowel disease.
Gastroenterology 2002;122(1):44-54.
2001: Wolfgang Kruis; Stefan Schreiber; D Theuer; J W Brandes; E Schütz; S Howaldt; Bernd Krakamp; J Hämling; H Mönnikes; I Koop; Manfred Stolte; D Pallant; U Ewald
Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses.
Gut 2001;49(6):783-9.
2001: Stefan Schreiber
Monocytes or T cells in Crohn's disease: does IL-16 allow both to play at that game?
Gut 2001;49(6):747-8.
2001: Jochen Hampe; Andreas Wollstein; Timothy Lu; H J Frevel; M Will; Carl Manaster; Stefan Schreiber
An integrated system for high throughput TaqMan based SNP genotyping.
Bioinformatics (Oxford, England) 2001;17(7):654-5.
2001: Jochen Hampe; Andrew P Cuthbert; Peter J P Croucher; Muddassar M Mirza; Silvia Mascheretti; S Fisher; Henning Frenzel; Kathy King; A Hasselmeyer; Andrew J S Macpherson; Stephen Bridger; SJ Van Deventer; Alastair Forbes; Susanna Nikolaus; John E Lennard-Jones; Ulrich R Foelsch; Michael Krawczak; C Lewis; Stefan Schreiber; Christopher G Mathew
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations.
Lancet 2001;357(9272):1925-8.
2001: Stefan Schreiber; Susanna Nikolaus; Helmut Malchow; Wolfgang Kruis; Herbert Lochs; Andreas Raedler; E G Hahn; T Krummenerl; G Steinmann
Absence of efficacy of subcutaneous antisense ICAM-1 treatment of chronic active Crohn's disease.
Gastroenterology 2001;120(6):1339-46.
2001: Tanja Kühbacher; Paolo Gionchetti; Jochen Hampe; Ulf Helwig; Philip Rosenstiel; Massimo Campieri; H J Buhr; Stefan Schreiber
Activation of signal-transducer and activator of transcription 1 (STAT1) in pouchitis.
Clinical and experimental immunology 2001;123(3):395-401.
2001: Dirk Seegert; Philip Rosenstiel; H Pfahler; P Pfefferkorn; Susanna Nikolaus; Stefan Schreiber
Increased expression of IL-16 in inflammatory bowel disease.
Gut 2001;48(3):326-32.
2001: Stefan Schreiber; Massimo Campieri; J F Colombel; S J van Deventer; B Feagan; R Fedorak; A Forbes; M Gassull; J P Gendre; R A van Hogezand; R Lofberg; Robert Modigliani; F Pallone; W Petritsch; Cosimo Prantera; D Rampton; F Seibold; M Vatn; M Zeitz; P Rutgeerts
Use of anti-tumour necrosis factor agents in inflammatory bowel disease. European guidelines for 2001-2003.
International journal of colorectal disease 2001;16(1):1-11; discussion 12-3.
2001: Jochen Hampe; Nicholas J Lynch; S Daniels; Stephen Bridger; Andrew J S Macpherson; Pieter C F Stokkers; Alastair Forbes; John E Lennard-Jones; Christopher G Mathew; Mark E Curran; Stefan Schreiber
Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease.
Gut 2001;48(2):191-7.
2000: Stefan Schreiber
Genetics of inflammatory bowel disease: a puzzle with contradictions?
Gut 2000;47(6):746-7.
2000: Stefan Schreiber; Jochen Hampe; Holger Eickhoff; Hans Lehrach
Functional genomics in gastroenterology.
Gut 2000;47(5):601-7.
2000: Susanna Nikolaus; Andreas Raedler; T Kühbacker; N Sfikas; Ulrich R Fölsch; Stefan Schreiber
Mechanisms in failure of infliximab for Crohn's disease.
Lancet 2000;356(9240):1475-9.
2000: Volker Kahlke; Christoph Dohm; Kerstin Brötzmann; Stefan Schreiber; Jörg Schröder
Gender-related therapy: early IL-10 administration after hemorrhage restores immune function in males but not in females.
Shock (Augusta, Ga.) 2000;14(3):354-9; discussion 359-60.
2000: Jochen Hampe; K Heymann; Wolfgang Kruis; Andreas Raedler; Ulrich R Fölsch; Stefan Schreiber
Anticipation in inflammatory bowel disease: a phenomenon caused by an accumulation of confounders.
American journal of medical genetics 2000;92(3):178-83.
2000: Jochen Hampe; T Wienker; Peter Nürnberg; Stefan Schreiber
Mapping genes for polygenic disorders: considerations for study design in the complex trait of inflammatory bowel disease.
Human heredity 2000;50(2):91-101.
2000: S Nikolaus; U Fölscn; Stefan Schreiber
Immunopharmacology of 5-aminosalicylic acid and of glucocorticoids in the therapy of inflammatory bowel disease.
Hepato-gastroenterology 2000;47(31):71-82.
2000: Stefan Schreiber
Inflammatory bowel disease: immunologic concepts.
Hepato-gastroenterology 2000;47(31):15-28.
2000: MG Olavesen; Jochen Hampe; Muddassar M Mirza; Robert Saiz; Cathryn M Lewis; Stephen Bridger; D Teare; D F Easton; T Herrmann; G Scott; J Hirst; Jeremy Sanderson; Shirley V Hodgson; J Lee; A MacPherson; Stefan Schreiber; John E Lennard-Jones; Mark E Curran; Christopher G Mathew
Analysis of single-nucleotide polymorphisms in the interleukin-4 receptor gene for association with inflammatory bowel disease.
Immunogenetics 2000;51(1):1-7.
1999: Jochen Hampe; Sarah H Shaw; Robert Saiz; N Leysens; Annette Lantermann; Silvia Mascheretti; Nicholas J Lynch; Andrew J S Macpherson; Stephen Bridger; SJ Van Deventer; Pieter C F Stokkers; P Morin; Muddassar M Mirza; Alastair Forbes; John E Lennard-Jones; Christopher G Mathew; Mark E Curran; Stefan Schreiber
Linkage of inflammatory bowel disease to human chromosome 6p.
American journal of human genetics 1999;65(6):1647-55.
1999: Nicole Bregenzer; I Caesar; Tilo Andus; J Hämling; Helmut Malchow; Stefan Schreiber; Jurgen Schölmerich
Lack of clinical efficacy of additional factor XIII treatment in patients with steroid refractory colitis. The Factor XIII Study Group.
Zeitschrift für Gastroenterologie 1999;37(10):999-1004.
1999: Stefan Schreiber; J Hampe
Genetics and inflammatory bowel disease.
Current opinion in gastroenterology 1999;15(4):315-21.
1999: Herbert Lochs; Guido Adler; C Beglinger; R Duchmann; J Emmrich; K Ewe; Alfred Gangl; C Gasché; E Hahn; P Hoffmann; Bernd A Kaskas; Helmut Malchow; C Pohl; Andreas Raedler; E Renner; Jurgen Schölmerich; Stefan Schreiber; Eduard F Stange; H Tilg; Harald Vogelsang; N Weigert; M Zeitz
Anti-TNF antibody in Crohn's disease--status of information, comments and recommendations of an international working group.
Zeitschrift für Gastroenterologie 1999;37(6):509-12.
1999: Jochen Hampe; Stefan Schreiber; Sarah H Shaw; K F Lau; Stephen Bridger; Andrew J S Macpherson; LR Cardon; H Sakul; T J Harris; AJ Buckler; J Hall; Pieter C F Stokkers; SJ Van Deventer; Peter Nürnberg; Muddassar M Mirza; J C Lee; John E Lennard-Jones; Christopher G Mathew; Mark E Curran
A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.
American journal of human genetics 1999;64(3):808-16.
1999: Stefan Schreiber
Activation of nuclear factor kappaB as a target for anti-inflammatory therapy.
Gut 1999;44(3):309-10.
1999: Stefan Schreiber; Susanna Nikolaus; Jochen Hampe; J Hämling; I Koop; B Groessner; Herbert Lochs; Andreas Raedler
Tumour necrosis factor alpha and interleukin 1beta in relapse of Crohn's disease.
Lancet 1999;353(9151):459-61.
1998: Mark E Curran; K F Lau; Jochen Hampe; Stefan Schreiber; Stephen Bridger; Andrew J S Macpherson; LR Cardon; H Sakul; T J Harris; Pieter C F Stokkers; SJ Van Deventer; Muddassar M Mirza; Andreas Raedler; Wolfgang Kruis; U Meckler; D Theuer; T Herrmann; P Gionchetti; J Lee; Christopher G Mathew; John E Lennard-Jones
Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16.
Gastroenterology 1998;115(5):1066-71.
1998: Wolfgang Kruis; J W Brandes; Stefan Schreiber; D Theuer; Bernd Krakamp; E Schütz; P Otto; H Lorenz-Mayer; K Ewe; G Judmaier
Olsalazine versus mesalazine in the treatment of mild to moderate ulcerative colitis.
Alimentary pharmacology & therapeutics 1998;12(8):707-15.
1998: Alexander Swidsinski; M Khilkin; D Kerjaschki; Stefan Schreiber; Maria-Anna Ortner; Jutta Weber; Herbert Lochs
Association between intraepithelial Escherichia coli and colorectal cancer.
Gastroenterology 1998;115(2):281-6.
1998: Stefan Schreiber; S Nikolaus; J Hampe
Activation of nuclear factor kappa B inflammatory bowel disease.
Gut 1998;42(4):477-84.
1998: S Nikolaus; Juergen Bauditz; P Gionchetti; C Witt; Herbert Lochs; Stefan Schreiber
Increased secretion of pro-inflammatory cytokines by circulating polymorphonuclear neutrophils and regulation by interleukin 10 during intestinal inflammation.
Gut 1998;42(4):470-6.
1998: Stefan Schreiber; I Koop
[Clinical effectiveness of short-term administration of monoclonal antibody cA2 against tumor necrosis factor alpha in Crohn disease].
Zeitschrift für Gastroenterologie 1998;36(4):349-51.
1998: Juergen Bauditz; H Lochs; Stefan Schreiber
Chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease.
The New England journal of medicine 1998;338(5):334.
1998: Jochen Hampe; B Hermann; Stephen Bridger; Andrew J S Macpherson; Christopher G Mathew; Stefan Schreiber
The interferon-gamma gene as a positional and functional candidate gene for inflammatory bowel disease.
International journal of colorectal disease 1998;13(5-6):260-3.
1998: Tanja Kühbacher; Stefan Schreiber; N Runkel
Pouchitis: pathophysiology and treatment.
International journal of colorectal disease 1998;13(5-6):196-207.
1997: Stefan Schreiber
Interleukin-10 in the intestine.
Gut 1997;41(2):274-5.
1997: Eduard F Stange; Stefan Schreiber; Andreas Raedler; A Stallmach; Jurgen Schölmerich; K Loeschke; M Starlinger; W Fischbach; W F Caspary
[Therapy of Crohn diseases--results of a Consensus Conference of the German Society of Digestive and Metabolic Diseases].
Zeitschrift für Gastroenterologie 1997;35(7):541-54.
1997: Stefan Schreiber; J Hämling; Elmar Zehnter; S Howaldt; W Daerr; Andreas Raedler; Wolfgang Kruis
Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate.
Gut 1997;40(6):761-6.
1997: Stefan Schreiber; S Wedel
Diagnosis and treatment of anemia in inflammatory bowel disease.
Inflammatory bowel diseases 1997;3(3):204-16.
1997: J Hämling; Andreas Raedler; U Helmchen; Stefan Schreiber
5-Aminosalicylic acid-associated renal tubular acidosis with decreased renal function in Crohn's disease.
Digestion 1997;58(3):304-7.
1996: Stefan Schreiber; S Howaldt; M Schnoor; S Nikolaus; Juergen Bauditz; C Gasché; H Lochs; Andreas Raedler
Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease.
The New England journal of medicine 1996;334(10):619-23.
1995: Juergen Bauditz; Y Rückert; Andreas Raedler; S Nikolaus; Herbert Lochs; Stefan Schreiber
Tumour necrosis factor inhibition by oxpentifylline and intestinal inflammation in Crohn's disease.
Lancet 1995;345(8962):1445.
1995: Stefan Schreiber; T Heinig; HG Thiele; Andreas Raedler
Immunoregulatory role of interleukin 10 in patients with inflammatory bowel disease.
Gastroenterology 1995;108(5):1434-44.
1995: Stefan Schreiber; T Heinig; Ulf Panzer; R Reinking; A Bouchard; P D Stahl; Andreas Raedler
Impaired response of activated mononuclear phagocytes to interleukin 4 in inflammatory bowel disease.
Gastroenterology 1995;108(1):21-33.
1994: Stefan Schreiber; S Howaldt; Andreas Raedler
Oral 4-aminosalicylic acid versus 5-aminosalicylic acid slow release tablets. Double blind, controlled pilot study in the maintenance treatment of Crohn's ileocolitis.
Gut 1994;35(8):1081-5.
1990: Andreas Raedler; Stefan Schreiber; A de Weerth; A Voss; S Peters; Heiner Greten
Assessment of in vivo activated T cells in patients with Crohn's disease.
Hepato-gastroenterology 1990;37(1):67-71.
1988: Andreas Raedler; H J Lenz; K Sandgren; A de Weerth; S Enversen; Stefan Schreiber; HG Thiele; Heiner Greten
Phenotype and functional properties of Vicia villosa agglutinin (VVA) binding T cells in patients with Crohn's disease: detection of contrasuppressor activity in patients lacking extra-intestinal manifestations, abscesses and fistulas.
Clinical and experimental immunology 1988;74(2):264-9.
1988: Andreas Raedler; Stefan Schreiber; K H Schulz; S Peters; Heiner Greten; HG Thiele
Activated Fc alpha T cells in Crohn's disease are involved in regulation of IgA.
Advances in experimental medicine and biology 1988;237():665-73.
1988: Andreas Raedler; Stefan Schreiber; A de Weerth; B Brinkmann; K Sandgren; HG Thiele; Heiner Greten
Evidence for contrasuppression in patients with Crohn's disease.
Advances in experimental medicine and biology 1988;237():655-63.