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Robert A. Weinberg

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Gupta Piyush B; Chaffer Christine L; Weinberg Robert A
Cancer stem cells: mirage or reality?
Gupta Piyush B; Onder Tamer T; Jiang Guozhi; Tao Kai; Kuperwasser Charlotte; Weinberg Robert A; Lander Eric S
Identification of selective inhibitors of cancer stem cells by high-throughput screening.
Valastyan Scott; Reinhardt Ferenc; Benaich Nathan; Calogrias Diana; Szász Attila M; Wang Zhigang C; Brock Jane E; Richardson Andrea L; Weinberg Robert A
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis.

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All Publications

2009: Gupta Piyush B; Chaffer Christine L; Weinberg Robert A
Cancer stem cells: mirage or reality?
Nature medicine 2009;15(9):1010-2.
2009: Gupta Piyush B; Onder Tamer T; Jiang Guozhi; Tao Kai; Kuperwasser Charlotte; Weinberg Robert A; Lander Eric S
Identification of selective inhibitors of cancer stem cells by high-throughput screening.
Cell 2009;138(4):645-59.
2009: Valastyan Scott; Reinhardt Ferenc; Benaich Nathan; Calogrias Diana; Szász Attila M; Wang Zhigang C; Brock Jane E; Richardson Andrea L; Weinberg Robert A
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis.
Cell 2009;137(6):1032-46.
2009: Shibue Tsukasa; Weinberg Robert A
Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10290-5.
2009: Kalluri Raghu; Weinberg Robert A
The basics of epithelial-mesenchymal transition.
The Journal of clinical investigation 2009;119(6):1420-8.
2009: Polyak Kornelia; Weinberg Robert A
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits.
Nature reviews. Cancer 2009;9(4):265-73.
2009: Rai Priyamvada; Onder Tamer T; Young Jennifer J; McFaline Jose L; Pang Bo; Dedon Peter C; Weinberg Robert A
Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(1):169-74.
2008: Godar Samuel; Weinberg Robert A
Filling the mosaic of p53 actions: p53 represses RHAMM expression.
Cell cycle (Georgetown, Tex.) 2008;7(22):3479.
2008: Weinberg Robert A
Leaving home early: reexamination of the canonical models of tumor progression.
Cancer cell 2008;14(4):283-4.
2008: Weinberg Robert A
Twisted epithelial-mesenchymal transition blocks senescence.
Nature cell biology 2008;10(9):1021-3.
2008: Ma Li; Weinberg Robert A
Micromanagers of malignancy: role of microRNAs in regulating metastasis.
Trends in genetics : TIG 2008;24(9):448-56.
2008: Weinberg Robert A
The many faces of tumor dormancy.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2008;116(7-8):548-51.
2008: Godar Samuel; Ince Tan A; Bell George W; Feldser David; Donaher Joana Liu; Bergh Jonas; Liu Anne; Miu Kevin; Watnick Randolph S; Reinhardt Ferenc; McAllister Sandra S; Jacks Tyler; Weinberg Robert A
Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression.
Cell 2008;134(1):62-73.
2008: Karnoub Antoine E; Weinberg Robert A
Ras oncogenes: split personalities.
Nature reviews. Molecular cell biology 2008;9(7):517-31.
2008: Weinberg Robert A; Komaroff Anthony L
Health for life. Your lifestyle, your genes, and cancer.
Newsweek 2008;151(25):40-3.
2008: McAllister Sandra S; Gifford Ann M; Greiner Ashley L; Kelleher Stephen P; Saelzler Matthew P; Ince Tan A; Reinhardt Ferenc; Harris Lyndsay N; Hylander Bonnie L; Repasky Elizabeth A; Weinberg Robert A
Systemic endocrine instigation of indolent tumor growth requires osteopontin.
Cell 2008;133(6):994-1005.
2008: Yang Jing; Weinberg Robert A
Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis.
Developmental cell 2008;14(6):818-29.
2008: Weinberg Robert A
Mechanisms of malignant progression.
Carcinogenesis 2008;29(6):1092-5.
2008: Mani Sendurai A; Guo Wenjun; Liao Mai-Jing; Eaton Elinor Ng; Ayyanan Ayyakkannu; Zhou Alicia Y; Brooks Mary; Reinhard Ferenc; Zhang Cheng Cheng; Shipitsin Michail; Campbell Lauren L; Polyak Kornelia; Brisken Cathrin; Yang Jing; Weinberg Robert A
The epithelial-mesenchymal transition generates cells with properties of stem cells.
Cell 2008;133(4):704-15.
2008: Onder Tamer T; Gupta Piyush B; Mani Sendurai A; Yang Jing; Lander Eric S; Weinberg Robert A
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways.
Cancer research 2008;68(10):3645-54.
2008: Ben-Porath Ittai; Thomson Matthew W; Carey Vincent J; Ge Ruping; Bell George W; Regev Aviv; Weinberg Robert A
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors.
Nature genetics 2008;40(5):499-507.
2008: Weinberg Robert A
Coevolution in the tumor microenvironment.
Nature genetics 2008;40(5):494-5.
2008: Ma Li; Weinberg Robert A
MicroRNAs in malignant progression.
Cell cycle (Georgetown, Tex.) 2008;7(5):570-2.
2008: Hanahan Douglas; Weinberg Robert A
Retrospective: Judah Folkman (1933-2008).
Science (New York, N.Y.) 2008;319(5866):1055.
2007: Weinberg Robert A
Is metastasis predetermined?
Molecular oncology 2007;1(3):263-4; author reply 265-6.
2007: Scheel Christina; Onder Tamer; Karnoub Antoine; Weinberg Robert A
Adaptation versus selection: the origins of metastatic behavior.
Cancer research 2007;67(24):11476-9; discussion 11479-80.
2007: Karnoub Antoine E; Dash Ajeeta B; Vo Annie P; Sullivan Andrew; Brooks Mary W; Bell George W; Richardson Andrea L; Polyak Kornelia; Tubo Ross; Weinberg Robert A
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis.
Nature 2007;449(7162):557-63.
2007: Ma Li; Teruya-Feldstein Julie; Weinberg Robert A
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer.
Nature 2007;449(7163):682-8.
2007: Liao Mai-Jing; Zhang Cheng Cheng; Zhou Beiyan; Zimonjic Drazen B; Mani Sendurai A; Kaba Megan; Gifford Ann; Reinhardt Ferenc; Popescu Nicholas C; Guo Wenjun; Eaton Elinor Ng; Lodish Harvey F; Weinberg Robert A
Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity.
Cancer research 2007;67(17):8131-8.
2007: Ince Tan A; Richardson Andrea L; Bell George W; Saitoh Maki; Godar Samuel; Karnoub Antoine E; Iglehart James D; Weinberg Robert A
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes.
Cancer cell 2007;12(2):160-70.
2007: Mani Sendurai A; Yang Jing; Brooks Mary; Schwaninger Gunda; Zhou Alicia; Miura Naoyuki; Kutok Jeffery L; Hartwell Kimberly; Richardson Andrea L; Weinberg Robert A
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10069-74.
2007: Orimo Akira; Weinberg Robert A
Heterogeneity of stromal fibroblasts in tumors.
Cancer biology & therapy 2007;6(4):618-9.
2007: Gupta Piyush B; Proia David; Cingoz Oya; Weremowicz Janusz; Naber Stephen P; Weinberg Robert A; Kuperwasser Charlotte
Systemic stromal effects of estrogen promote the growth of estrogen receptor-negative cancers.
Cancer research 2007;67(5):2062-71.
2006: Weinberg Robert; Mihich Enrico
Eighteenth annual pezcoller symposium: tumor microenvironment and heterotypic interactions.
Cancer research 2006;66(24):11550-3.
2006: Hartwell Kimberly A; Muir Beth; Reinhardt Ferenc; Carpenter Anne E; Sgroi Dennis C; Weinberg Robert A
The Spemann organizer gene, Goosecoid, promotes tumor metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):18969-74.
2006: Orimo Akira; Weinberg Robert A
Stromal fibroblasts in cancer: a novel tumor-promoting cell type.
Cell cycle (Georgetown, Tex.) 2006;5(15):1597-601.
2006: Weinberg Robert A
A lost generation.
Cell 2006;126(1):9-10.
2006: Yang Jing; Mani Sendurai A; Weinberg Robert A
Exploring a new twist on tumor metastasis.
Cancer research 2006;66(9):4549-52.
2006: Karnoub Antoine E; Weinberg Robert A
Chemokine networks and breast cancer metastasis.
Breast disease 2006;26():75-85.
2006: Stewart Sheila A; Weinberg Robert A
Telomeres: cancer to human aging.
Annual review of cell and developmental biology 2006;22():531-57.
2005: Gupta Piyush B; Kuperwasser Charlotte; Brunet Jean-Philippe; Ramaswamy Sridhar; Kuo Wen-Lin; Gray Joe W; Naber Stephen P; Weinberg Robert A
The melanocyte differentiation program predisposes to metastasis after neoplastic transformation.
Nature genetics 2005;37(10):1047-54.
2005: Kuperwasser Charlotte; Dessain Scott; Bierbaum Benjamin E; Garnet Dan; Sperandio Kara; Gauvin Gregory P; Naber Stephen P; Weinberg Robert A; Rosenblatt Michael
A mouse model of human breast cancer metastasis to human bone.
Cancer research 2005;65(14):6130-8.
2005: Orimo Akira; Gupta Piyush B; Sgroi Dennis C; Arenzana-Seisdedos Fernando; Delaunay Thierry; Naeem Rizwan; Carey Vincent J; Richardson Andrea L; Weinberg Robert A
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion.
Cell 2005;121(3):335-48.
2005: Ben-Porath Ittai; Weinberg Robert A
The signals and pathways activating cellular senescence.
The international journal of biochemistry & cell biology 2005;37(5):961-76.
2005: Gupta P B; Mani S; Yang J; Hartwell K; Weinberg R A
The evolving portrait of cancer metastasis.
Cold Spring Harbor symposia on quantitative biology 2005;70():291-7.
2004: Dessain Scott K; Adekar Sharad P; Stevens Jennifer B; Carpenter Katherine A; Skorski Maria L; Barnoski Barry L; Goldsby Richard A; Weinberg Robert A
High efficiency creation of human monoclonal antibody-producing hybridomas.
Journal of immunological methods 2004;291(1-2):109-22.
2004: Rangarajan Annapoorni; Hong Sue J; Gifford Annie; Weinberg Robert A
Species- and cell type-specific requirements for cellular transformation.
Cancer cell 2004;6(2):171-83.
2004: Yang Jing; Mani Sendurai A; Donaher Joana Liu; Ramaswamy Sridhar; Itzykson Raphael A; Come Christophe; Savagner Pierre; Gitelman Inna; Richardson Andrea; Weinberg Robert A
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis.
Cell 2004;117(7):927-39.
2004: Kuperwasser Charlotte; Chavarria Tony; Wu Min; Magrane Greg; Gray Joe W; Carey Loucinda; Richardson Andrea; Weinberg Robert A
Reconstruction of functionally normal and malignant human breast tissues in mice.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4966-71.
2004: Weinberg Robert A
Inadvertent cancer research.
Cancer biology & therapy 2004;3(2):238-9.
2004: Ben-Porath Ittai; Weinberg Robert A
When cells get stressed: an integrative view of cellular senescence.
The Journal of clinical investigation 2004;113(1):8-13.
2003: Rangarajan Annapoorni; Weinberg Robert A
Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice.
Nature reviews. Cancer 2003;3(12):952-9.
2003: Masutomi Kenkichi; Yu Evan Y; Khurts Shilagardy; Ben-Porath Ittai; Currier Jennifer L; Metz Geoffrey B; Brooks Mary W; Kaneko Shuichi; Murakami Seishi; DeCaprio James A; Weinberg Robert A; Stewart Sheila A; Hahn William C
Telomerase maintains telomere structure in normal human cells.
Cell 2003;114(2):241-53.
2003: Stenvers Kaye L; Tursky Melinda L; Harder Kenneth W; Kountouri Nicole; Amatayakul-Chantler Supavadee; Grail Dianne; Small Clayton; Weinberg Robert A; Sizeland Andrew M; Zhu Hong-Jian
Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos.
Molecular and cellular biology 2003;23(12):4371-85.
2003: Stewart Sheila A; Ben-Porath Ittai; Carey Vincent J; O'Connor Benjamin F; Hahn William C; Weinberg Robert A
Erosion of the telomeric single-strand overhang at replicative senescence.
Nature genetics 2003;33(4):492-6.
2003: Stewart Sheila A; Dykxhoorn Derek M; Palliser Deborah; Mizuno Hana; Yu Evan Y; An Dong Sung; Sabatini David M; Chen Irvin S Y; Hahn William C; Sharp Phillip A; Weinberg Robert A; Novina Carl D
Lentivirus-delivered stable gene silencing by RNAi in primary cells.
RNA (New York, N.Y.) 2003;9(4):493-501.
2003: Watnick Randolph S; Cheng Yi-Ning; Rangarajan Annapoorni; Ince Tan A; Weinberg Robert A
Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis.
Cancer cell 2003;3(3):219-31.
2002: Jacks Tyler; Weinberg Robert A
Taking the study of cancer cell survival to a new dimension.
Cell 2002;111(7):923-5.
2002: Brisken Cathrin; Ayyannan Ayyakkannu; Nguyen Cuc; Heineman Anna; Reinhardt Ferenc; Tan Jian; Dey S K; Dotto G Paolo; Weinberg Robert A;
IGF-2 is a mediator of prolactin-induced morphogenesis in the breast.
Developmental cell 2002;3(6):877-87.
2002: Hahn William C; Weinberg Robert A
Rules for making human tumor cells.
The New England journal of medicine 2002;347(20):1593-603.
2002: Brisken Cathrin; Socolovsky Merav; Lodish Harvey F; Weinberg Robert
The signaling domain of the erythropoietin receptor rescues prolactin receptor-mutant mammary epithelium.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14241-5.
2002: Stewart Sheila A; Hahn William C; O'Connor Benjamin F; Banner Elisa N; Lundberg Ante S; Modha Poonam; Mizuno Hana; Brooks Mary W; Fleming Mark; Zimonjic Drazen B; Popescu Nicholas C; Weinberg Robert A
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(20):12606-11.
2002: Bernards René; Weinberg Robert A
A progression puzzle.
Nature 2002;418(6900):823.
2002: Lundberg Ante S; Randell Scott H; Stewart Sheila A; Elenbaas Brian; Hartwell Kimberly A; Brooks Mary W; Fleming Mark D; Olsen John C; Miller Scott W; Weinberg Robert A; Hahn William C
Immortalization and transformation of primary human airway epithelial cells by gene transfer.
Oncogene 2002;21(29):4577-86.
2002: Hahn William C; Weinberg Robert A
Modelling the molecular circuitry of cancer.
Nature reviews. Cancer 2002;2(5):331-41.
2002: Hahn William C; Dessain Scott K; Brooks Mary W; King Jessie E; Elenbaas Brian; Sabatini David M; DeCaprio James A; Weinberg Robert A
Enumeration of the simian virus 40 early region elements necessary for human cell transformation.
Molecular and cellular biology 2002;22(7):2111-23.
2002: Ince Tan A; Weinberg Robert A
Functional genomics and the breast cancer problem.
Cancer cell 2002;1(1):15-7.
2002: Weinberg Robert A
Cancer Biology and Therapy: the road ahead.
Cancer biology & therapy 2002;1(1):3.
2002: Stewart Sheila A; Weinberg Robert A
Senescence: does it all happen at the ends?
Oncogene 2002;21(4):627-30.
2001: Zimonjic D; Brooks M W; Popescu N; Weinberg R A; Hahn W C
Derivation of human tumor cells in vitro without widespread genomic instability.
Cancer research 2001;61(24):8838-44.
2001: Vaziri H; Dessain S K; Ng Eaton E; Imai S I; Frye R A; Pandita T K; Guarente L; Weinberg R A
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.
Cell 2001;107(2):149-59.
2001: Perlman R; Schiemann W P; Brooks M W; Lodish H F; Weinberg R A
TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.
Nature cell biology 2001;3(8):708-14.
2001: Planas-Silva M D; Shang Y; Donaher J L; Brown M; Weinberg R A
AIB1 enhances estrogen-dependent induction of cyclin D1 expression.
Cancer research 2001;61(10):3858-62.
2001: Schratt G; Weinhold B; Lundberg A S; Schuck S; Berger J; Schwarz H; Weinberg R A; Rüther U; Nordheim A
Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells.
Molecular and cellular biology 2001;21(8):2933-43.
2001: Liu X; Sun Y; Weinberg R A; Lodish H F
Ski/Sno and TGF-beta signaling.
Cytokine & growth factor reviews 2001;12(1):1-8.
2001: Elenbaas B; Weinberg R A
Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation.
Experimental cell research 2001;264(1):169-84.
2001: Elenbaas B; Spirio L; Koerner F; Fleming M D; Zimonjic D B; Donaher J L; Popescu N C; Hahn W C; Weinberg R A
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells.
Genes & development 2001;15(1):50-65.
2000: Stewart S A; Weinberg R A
Telomerase and human tumorigenesis.
Seminars in cancer biology 2000;10(6):399-406.
2000: Lundberg A S; Hahn W C; Gupta P; Weinberg R A
Genes involved in senescence and immortalization.
Current opinion in cell biology 2000;12(6):705-9.
2000: Liu X; Sun Y; Ehrlich M; Lu T; Kloog Y; Weinberg R A; Lodish H F; Henis Y I
Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization.
Oncogene 2000;19(51):5926-35.
2000: Solvason N; Wu W W; Parry D; Mahony D; Lam E W; Glassford J; Klaus G G; Sicinski P; Weinberg R; Liu Y J; Howard M; Lees E
Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development.
International immunology 2000;12(5):631-8.
2000: Liu X; Constantinescu S N; Sun Y; Bogan J S; Hirsch D; Weinberg R A; Lodish H F
Generation of mammalian cells stably expressing multiple genes at predetermined levels.
Analytical biochemistry 2000;280(1):20-8.
2000: Lander E S; Weinberg R A
Genomics: journey to the center of biology.
Science (New York, N.Y.) 2000;287(5459):1777-82.
2000: Brisken C; Heineman A; Chavarria T; Elenbaas B; Tan J; Dey S K; McMahon J A; McMahon A P; Weinberg R A
Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling.
Genes & development 2000;14(6):650-4.
2000: Dessain S K; Yu H; Reddel R R; Beijersbergen R L; Weinberg R A
Methylation of the human telomerase gene CpG island.
Cancer research 2000;60(3):537-41.
2000: Dickson M A; Hahn W C; Ino Y; Ronfard V; Wu J Y; Weinberg R A; Louis D N; Li F P; Rheinwald J G
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.
Molecular and cellular biology 2000;20(4):1436-47.
2000: Hanahan D; Weinberg R A
The hallmarks of cancer.
Cell 2000;100(1):57-70.
1999: Lundberg A S; Weinberg R A
Control of the cell cycle and apoptosis.
European journal of cancer (Oxford, England : 1990) 1999;35(14):1886-94.
1999: Sun Y; Liu X; Eaton E N; Lane W S; Lodish H F; Weinberg R A
Interaction of the Ski oncoprotein with Smad3 regulates TGF-beta signaling.
Molecular cell 1999;4(4):499-509.
1999: Sun Y; Liu X; Ng-Eaton E; Lodish H F; Weinberg R A
SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12442-7.
1999: Planas-Silva M D; Donaher J L; Weinberg R A
Functional activity of ectopically expressed estrogen receptor is not sufficient for estrogen-mediated cyclin D1 expression.
Cancer research 1999;59(19):4788-92.
1999: Hahn W C; Stewart S A; Brooks M W; York S G; Eaton E; Kurachi A; Beijersbergen R L; Knoll J H; Meyerson M; Weinberg R A
Inhibition of telomerase limits the growth of human cancer cells.
Nature medicine 1999;5(10):1164-70.
1999: Weinberg R
Ernst Ludwig Wynder 1922-99.
Nature 1999;401(6752):442.
1999: Hahn W C; Counter C M; Lundberg A S; Beijersbergen R L; Brooks M W; Weinberg R A
Creation of human tumour cells with defined genetic elements.
Nature 1999;400(6743):464-8.
1999: Geng Y; Whoriskey W; Park M Y; Bronson R T; Medema R H; Li T; Weinberg R A; Sicinski P
Rescue of cyclin D1 deficiency by knockin cyclin E.
Cell 1999;97(6):767-77.
1999: Brisken C; Kaur S; Chavarria T E; Binart N; Sutherland R L; Weinberg R A; Kelly P A; Ormandy C J
Prolactin controls mammary gland development via direct and indirect mechanisms.
Developmental biology 1999;210(1):96-106.
1999: Lundberg A S; Weinberg R A
Control of the cell cycle and apoptosis.
European journal of cancer (Oxford, England : 1990) 1999;35(4):531-9.
1999: Lees J A; Weinberg R A
Tossing monkey wrenches into the clock: new ways of treating cancer.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4221-3.
1998: Counter C M; Hahn W C; Wei W; Caddle S D; Beijersbergen R L; Lansdorp P M; Sedivy J M; Weinberg R A
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14723-8.
1998: Weinberg R A
Telomeres. Bumps on the road to immortality.
Nature 1998;396(6706):23-4.
1998: Robles A I; Rodriguez-Puebla M L; Glick A B; Trempus C; Hansen L; Sicinski P; Tennant R W; Weinberg R A; Yuspa S H; Conti C J
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo.
Genes & development 1998;12(16):2469-74.
1998: Kolquist K A; Ellisen L W; Counter C M; Meyerson M; Tan L K; Weinberg R A; Haber D A; Gerald W L
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.
Nature genetics 1998;19(2):182-6.
1998: Jacks T; Weinberg R A
The expanding role of cell cycle regulators.
Science (New York, N.Y.) 1998;280(5366):1035-6.
1998: Brisken C; Park S; Vass T; Lydon J P; O'Malley B W; Weinberg R A
A paracrine role for the epithelial progesterone receptor in mammary gland development.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):5076-81.
1998: Counter C M; Meyerson M; Eaton E N; Ellisen L W; Caddle S D; Haber D A; Weinberg R A
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase.
Oncogene 1998;16(9):1217-22.
1998: Orr-Weaver T L; Weinberg R A
A checkpoint on the road to cancer.
Nature 1998;392(6673):223-4.
1998: Lundberg A S; Weinberg R A
Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes.
Molecular and cellular biology 1998;18(2):753-61.
1997: Planas-Silva M D; Weinberg R A
The restriction point and control of cell proliferation.
Current opinion in cell biology 1997;9(6):768-72.
1997: Sicinski P; Weinberg R A
A specific role for cyclin D1 in mammary gland development.
Journal of mammary gland biology and neoplasia 1997;2(4):335-42.
1997: Liu X; Sun Y; Constantinescu S N; Karam E; Weinberg R A; Lodish H F
Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(20):10669-74.
1997: Fazeli A; Steen R G; Dickinson S L; Bautista D; Dietrich W F; Bronson R T; Bresalier R S; Lander E S; Costa J; Weinberg R A
Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(19):10199-204.
1997: Meyerson M; Counter C M; Eaton E N; Ellisen L W; Steiner P; Caddle S D; Ziaugra L; Beijersbergen R L; Davidoff M J; Liu Q; Bacchetti S; Haber D A; Weinberg R A
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
Cell 1997;90(4):785-95.
1997: Counter C M; Meyerson M; Eaton E N; Weinberg R A
The catalytic subunit of yeast telomerase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9202-7.
1997: Steiner P; Barnes D M; Harris W H; Weinberg R A
Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer.
Nature genetics 1997;16(4):332-3.
1997: Planas-Silva M D; Weinberg R A
Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution.
Molecular and cellular biology 1997;17(7):4059-69.
1997: Fazeli A; Dickinson S L; Hermiston M L; Tighe R V; Steen R G; Small C G; Stoeckli E T; Keino-Masu K; Masu M; Rayburn H; Simons J; Bronson R T; Gordon J I; Tessier-Lavigne M; Weinberg R A
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene.
Nature 1997;386(6627):796-804.
1997: Weinberg R A
The cat and mouse games that genes, viruses, and cells play.
Cell 1997;88(5):573-5.
1997: Leonardo E D; Hinck L; Masu M; Keino-Masu K; Fazeli A; Stoeckli E T; Ackerman S L; Weinberg R A; Tessier-Lavigne M
Guidance of developing axons by netrin-1 and its receptors.
Cold Spring Harbor symposia on quantitative biology 1997;62():467-78.
1996: Sicinski P; Donaher J L; Geng Y; Parker S B; Gardner H; Park M Y; Robker R L; Richards J S; McGinnis L K; Biggers J D; Eppig J J; Bronson R T; Elledge S J; Weinberg R A
Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
Nature 1996;384(6608):470-4.
1996: Herrera R E; Chen F; Weinberg R A
Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11510-5.
1996: Herrera R E; Mäkelä T P; Weinberg R A
TGF beta-induced growth inhibition in primary fibroblasts requires the retinoblastoma protein.
Molecular biology of the cell 1996;7(9):1335-42.
1996: Weinberg R A
How cancer arises.
Scientific American 1996;275(3):62-70.
1996: Cobrinik D; Lee M H; Hannon G; Mulligan G; Bronson R T; Dyson N; Harlow E; Beach D; Weinberg R A; Jacks T
Shared role of the pRB-related p130 and p107 proteins in limb development.
Genes & development 1996;10(13):1633-44.
1996: Wang Z; Sicinski P; Weinberg R A; Zhang Y; Ravid K
Characterization of the mouse cyclin D3 gene: exon/intron organization and promoter activity.
Genomics 1996;35(1):156-63.
1996: Weinberg R A
The molecular basis of carcinogenesis: understanding the cell cycle clock.
Cytokines and molecular therapy 1996;2(2):105-10.
1996: Jacks T; Weinberg R A
Cell-cycle control and its watchman.
Nature 1996;381(6584):643-4.
1996: Weinberg R A
E2F and cell proliferation: a world turned upside down.
Cell 1996;85(4):457-9.
1996: Herrera R E; Sah V P; Williams B O; Mäkelä T P; Weinberg R A; Jacks T
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.
Molecular and cellular biology 1996;16(5):2402-7.
1996: Geng Y; Eaton E N; Picón M; Roberts J M; Lundberg A S; Gifford A; Sardet C; Weinberg R A
Regulation of cyclin E transcription by E2Fs and retinoblastoma protein.
Oncogene 1996;12(6):1173-80.
1995: Park S H; Weinberg R A
A putative effector of Ral has homology to Rho/Rac GTPase activating proteins.
Oncogene 1995;11(11):2349-55.
1995: Akoulitchev S; Mäkelä T P; Weinberg R A; Reinberg D
Requirement for TFIIH kinase activity in transcription by RNA polymerase II.
Nature 1995;377(6549):557-60.
1995: Clarkson B; Chabner B A; Weinberg R A
Targets for specific therapies in leukemia.
Cancer research 1995;55(19):4488-98.
1995: Sicinski P; Donaher J L; Parker S B; Li T; Fazeli A; Gardner H; Haslam S Z; Bronson R T; Elledge S J; Weinberg R A
Cyclin D1 provides a link between development and oncogenesis in the retina and breast.
Cell 1995;82(4):621-30.
1995: Rodriguez C; Chen F; Weinberg R A; Lodish H F
Cooperative binding of transforming growth factor (TGF)-beta 2 to the types I and II TGF-beta receptors.
The Journal of biological chemistry 1995;270(27):15919-22.
1995: Medema R H; Herrera R E; Lam F; Weinberg R A
Growth suppression by p16ink4 requires functional retinoblastoma protein.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6289-93.
1995: Weinberg R A
The molecular basis of oncogenes and tumor suppressor genes.
Annals of the New York Academy of Sciences 1995;758():331-8.
1995: Mäkelä T P; Parvin J D; Kim J; Huber L J; Sharp P A; Weinberg R A
A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(11):5174-8.
1995: Weinberg R A
The retinoblastoma protein and cell cycle control.
Cell 1995;81(3):323-30.
1995: Laird P W; Jackson-Grusby L; Fazeli A; Dickinson S L; Jung W E; Li E; Weinberg R A; Jaenisch R
Suppression of intestinal neoplasia by DNA hypomethylation.
Cell 1995;81(2):197-205.
1995: Sardet C; Vidal M; Cobrinik D; Geng Y; Onufryk C; Chen A; Weinberg R A
E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(6):2403-7.
1995: Serizawa H; Mäkelä T P; Conaway J W; Conaway R C; Weinberg R A; Young R A
Association of Cdk-activating kinase subunits with transcription factor TFIIH.
Nature 1995;374(6519):280-2.
1995: Chen F; Weinberg R A
Biochemical evidence for the autophosphorylation and transphosphorylation of transforming growth factor beta receptor kinases.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1565-9.
1995: Hatakeyama M; Weinberg R A
The role of RB in cell cycle control.
Progress in cell cycle research 1995;1():9-19.
1995: Weinberg R A
Prospects for cancer genetics.
Cancer surveys 1995;25():3-12.
1994: Mäkelä T P; Tassan J P; Nigg E A; Frutiger S; Hughes G J; Weinberg R A
A cyclin associated with the CDK-activating kinase MO15.
Nature 1994;371(6494):254-7.
1994: Williams B O; Schmitt E M; Remington L; Bronson R T; Albert D M; Weinberg R A; Jacks T
Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences.
The EMBO journal 1994;13(18):4251-9.
1994: Hatakeyama M; Brill J A; Fink G R; Weinberg R A
Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein.
Genes & development 1994;8(15):1759-71.
1994: Jacks T; Shih T S; Schmitt E M; Bronson R T; Bernards A; Weinberg R A
Tumour predisposition in mice heterozygous for a targeted mutation in Nf1.
Nature genetics 1994;7(3):353-61.
1994: Weinberg R A
You can't get there from here: the tortuous road to basic research.
Academic medicine : journal of the Association of American Medical Colleges 1994;69(6):441-4.
1994: Weinberg R A
Oncogenes and tumor suppressor genes.
CA: a cancer journal for clinicians 1994;44(3):160-70.
1994: Hinds P W; Weinberg R A
Tumor suppressor genes.
Current opinion in genetics & development 1994;4(1):135-41.
1994: Mittnacht S; Lees J A; Desai D; Harlow E; Morgan D O; Weinberg R A
Distinct sub-populations of the retinoblastoma protein show a distinct pattern of phosphorylation.
The EMBO journal 1994;13(1):118-27.
1994: Hinds P W; Dowdy S F; Eaton E N; Arnold A; Weinberg R A
Function of a human cyclin gene as an oncogene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(2):709-13.
1994: Jacks T; Remington L; Williams B O; Schmitt E M; Halachmi S; Bronson R T; Weinberg R A
Tumor spectrum analysis in p53-mutant mice.
Current biology : CB 1994;4(1):1-7.
1994: Hatakeyama M; Herrera R A; Makela T; Dowdy S F; Jacks T; Weinberg R A
The cancer cell and the cell cycle clock.
Cold Spring Harbor symposia on quantitative biology 1994;59():1-10.
1993: Cobrinik D; Whyte P; Peeper D S; Jacks T; Weinberg R A
Cell cycle-specific association of E2F with the p130 E1A-binding protein.
Genes & development 1993;7(12A):2392-404.
1993: Warner L C; Hack N; Egan S E; Goldberg H J; Weinberg R A; Skorecki K L
RAS is required for epidermal growth factor-stimulated arachidonic acid release in rat-1 fibroblasts.
Oncogene 1993;8(12):3249-55.
1993: Geng Y; Weinberg R A
Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10315-9.
1993: Egan S E; Weinberg R A
The pathway to signal achievement.
Nature 1993;365(6449):781-3.
1993: Weinberg R
Tumor suppressor genes.
Neuron 1993;11(2):191-6.
1993: Dowdy S F; Hinds P W; Louie K; Reed S I; Arnold A; Weinberg R A
Physical interaction of the retinoblastoma protein with human D cyclins.
Cell 1993;73(3):499-511.
1993: Egan S E; Giddings B W; Brooks M W; Buday L; Sizeland A M; Weinberg R A
Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation.
Nature 1993;363(6424):45-51.
1993: Albright C F; Giddings B W; Liu J; Vito M; Weinberg R A
Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase.
The EMBO journal 1993;12(1):339-47.
1992: Settleman J; Albright C F; Foster L C; Weinberg R A
Association between GTPase activators for Rho and Ras families.
Nature 1992;359(6391):153-4.
1992: Weinberg R A
The integration of molecular genetics into cancer management.
Cancer 1992;70(6 Suppl):1653-8.
1992: Jacks T; Fazeli A; Schmitt E M; Bronson R T; Goodell M A; Weinberg R A
Effects of an Rb mutation in the mouse.
Nature 1992;359(6393):295-300.
1992: Hinds P W; Mittnacht S; Dulic V; Arnold A; Reed S I; Weinberg R A
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins.
Cell 1992;70(6):993-1006.
1992: Cobrinik D; Dowdy S F; Hinds P W; Mittnacht S; Weinberg R A
The retinoblastoma protein and the regulation of cell cycling.
Trends in biochemical sciences 1992;17(8):312-5.
1992: Yu Q; Lenardo T; Weinberg R A
The N-terminal and C-terminal domains of a receptor tyrosine phosphatase are associated by non-covalent linkage.
Oncogene 1992;7(6):1051-7.
1992: Settleman J; Narasimhan V; Foster L C; Weinberg R A
Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus.
Cell 1992;69(3):539-49.
1992: Ikawa S; Weinberg R A
An interaction between p21ras and heat shock protein hsp60, a chaperonin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(6):2012-6.
1992: Massagué J; Weinberg R A
Negative regulators of growth.
Current opinion in genetics & development 1992;2(1):28-32.
1992: Lin H Y; Wang X F; Ng-Eaton E; Weinberg R A; Lodish H F
Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase.
Cell 1992;68(4):775-85.
1992: Weinberg R A
The retinoblastoma gene and gene product.
Cancer surveys 1992;12():43-57.
1991: Weinberg R A
Tumor suppressor genes.
Science (New York, N.Y.) 1991;254(5035):1138-46.
1991: Wang X F; Lin H Y; Ng-Eaton E; Downward J; Lodish H F; Weinberg R A
Expression cloning and characterization of the TGF-beta type III receptor.
Cell 1991;67(4):797-805.
1991: Mittnacht S; Weinberg R A
G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment.
Cell 1991;65(3):381-93.
1991: Templeton D J; Park S H; Lanier L; Weinberg R A
Nonfunctional mutants of the retinoblastoma protein are characterized by defects in phosphorylation, viral oncoprotein association, and nuclear tethering.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3033-7.
1991: Weinberg R A
The human genome initiative. There are two large questions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(1):78.
1991: Mittnacht S; Hinds P W; Dowdy S F; Weinberg R A
Modulation of retinoblastoma protein activity during the cell cycle.
Cold Spring Harbor symposia on quantitative biology 1991;56():197-209.
1990: Downward J; Riehl R; Wu L; Weinberg R A
Identification of a nucleotide exchange-promoting activity for p21ras.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5998-6002.
1990: Weinberg R A
The retinoblastoma gene and cell growth control.
Trends in biochemical sciences 1990;15(5):199-202.
1990: Horowitz J M; Park S H; Bogenmann E; Cheng J C; Yandell D W; Kaye F J; Minna J D; Dryja T P; Weinberg R A
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(7):2775-9.
1990: Weinberg R A
The genetic bases of cancer. Lucy Wortham James lecture.
Archives of surgery (Chicago, Ill. : 1960) 1990;125(2):257-60.
1990: Weinberg R A
Negative growth controls and carcinogenesis.
Molecular carcinogenesis 1990;3(1):3-4.
1989: Weinberg R A
Positive and negative controls on cell growth.
Biochemistry 1989;28(21):8263-9.
1989: Weinberg R A
The Rb gene and the negative regulation of cell growth.
Blood 1989;74(2):529-32.
1989: Weinberg R A
Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis.
Cancer research 1989;49(14):3713-21.
1989: de Gunzburg J; Riehl R; Weinberg R A
Identification of a protein associated with p21ras by chemical crosslinking.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4007-11.
1989: Avraham H; Weinberg R A
Characterization and expression of the human rhoH12 gene product.
Molecular and cellular biology 1989;9(5):2058-66.
1989: Yarden Y; Weinberg R A
Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3179-83.
1989: Horowitz J M; Yandell D W; Park S H; Canning S; Whyte P; Buchkovich K; Harlow E; Weinberg R A; Dryja T P
Point mutational inactivation of the retinoblastoma antioncogene.
Science (New York, N.Y.) 1989;243(4893):937-40.
1989: Rogelj S; Weinberg R A; Fanning P; Klagsbrun M
Characterization of tumors produced by signal peptide-basic fibroblast growth factor-transformed cells.
Journal of cellular biochemistry 1989;39(1):13-23.
1989: Weinberg R A
The molecular basis of retinoblastomas.
Ciba Foundation symposium 1989;142():99-105; discussion 106-11.
1988: Weinberg R A
Oncogenes and tumor suppressor genes.
Transactions & studies of the College of Physicians of Philadelphia 1988;10(1-4):83-94.
1988: Weinberg R A
To sequence or not to sequence.
Scientific American 1988;259(5):150.
1988: Weinberg R A
Finding the anti-oncogene.
Scientific American 1988;259(3):44-51.
1988: Dotto G P; Weinberg R A; Ariza A
Malignant transformation of mouse primary keratinocytes by Harvey sarcoma virus and its modulation by surrounding normal cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6389-93.
1988: Downward J; de Gunzburg J; Riehl R; Weinberg R A
p21ras-induced responsiveness of phosphatidylinositol turnover to bradykinin is a receptor number effect.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5774-8.
1988: Bargmann C I; Weinberg R A
Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5394-8.
1988: Whyte P; Buchkovich K J; Horowitz J M; Friend S H; Raybuck M; Weinberg R A; Harlow E
Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product.
Nature 1988;334(6178):124-9.
1988: Bargmann C I; Weinberg R A
Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion.
The EMBO journal 1988;7(7):2043-52.
1988: Weinberg R A
The genetic origins of human cancer.
Cancer 1988;61(10):1963-8.
1988: Kimchi A; Wang X F; Weinberg R A; Cheifetz S; Massagué J
Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells.
Science (New York, N.Y.) 1988;240(4849):196-9.
1988: Friend S H; Dryja T P; Weinberg R A
Oncogenes and tumor-suppressing genes.
The New England journal of medicine 1988;318(10):618-22.
1988: Rogelj S; Weinberg R A; Fanning P; Klagsbrun M
Basic fibroblast growth factor fused to a signal peptide transforms cells.
Nature 1988;331(6152):173-5.
1988: Finklestein R; Weinberg R A
Differential regulation of N-myc and c-myc expression in F9 teratocarcinoma cells.
Oncogene research 1988;3(3):287-92.
1988: Downward J; Weinberg R A
Influence of p21ras on phosphatidylinositol turnover.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():883-92.
1988: Horowitz J M; Friend S H; Weinberg R A; Whyte P; Buchkovich K; Harlow E
Anti-oncogenes and the negative regulation of cell growth.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():843-7.
1987: Friend S H; Horowitz J M; Gerber M R; Wang X F; Bogenmann E; Li F P; Weinberg R A
Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):9059-63.
1987: Bernards R; Destree A; McKenzie S; Gordon E; Weinberg R A; Panicali D
Effective tumor immunotherapy directed against an oncogene-encoded product using a vaccinia virus vector.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(19):6854-8.
1987: Stern D F; Hare D L; Cecchini M A; Weinberg R A
Construction of a novel oncogene based on synthetic sequences encoding epidermal growth factor.
Science (New York, N.Y.) 1987;235(4786):321-4.
1986: Drebin J A; Link V C; Weinberg R A; Greene M I
Inhibition of tumor growth by a monoclonal antibody reactive with an oncogene-encoded tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):9129-33.
1986: Bernards R; Dessain S K; Weinberg R A
N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma.
Cell 1986;47(5):667-74.
1986: Gilman M Z; Wilson R N; Weinberg R A
Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression.
Molecular and cellular biology 1986;6(12):4305-16.
1986: Dotto G P; Gilman M Z; Maruyama M; Weinberg R A
c-myc and c-fos expression in differentiating mouse primary keratinocytes.
The EMBO journal 1986;5(11):2853-7.
1986: Friend S H; Bernards R; Rogelj S; Weinberg R A; Rapaport J M; Albert D M; Dryja T P
A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma.
Nature 1986;323(6089):643-6.
1986: Weinberg R A
Oncogenes and tumor progression.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1986;4(9):1293-4.
1986: Land H; Chen A C; Morgenstern J P; Parada L F; Weinberg R A
Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts.
Molecular and cellular biology 1986;6(6):1917-25.
1986: Bargmann C I; Hung M C; Weinberg R A
Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.
Cell 1986;45(5):649-57.
1986: Stern D F; Heffernan P A; Weinberg R A
p185, a product of the neu proto-oncogene, is a receptorlike protein associated with tyrosine kinase activity.
Molecular and cellular biology 1986;6(5):1729-40.
1986: McCoy M S; Weinberg R A
A human Ki-ras oncogene encodes two transforming p21 proteins.
Molecular and cellular biology 1986;6(4):1326-8.
1986: Stern D F; Roberts A B; Roche N S; Sporn M B; Weinberg R A
Differential responsiveness of myc- and ras-transfected cells to growth factors: selective stimulation of myc-transfected cells by epidermal growth factor.
Molecular and cellular biology 1986;6(3):870-7.
1986: Bargmann C I; Hung M C; Weinberg R A
The neu oncogene encodes an epidermal growth factor receptor-related protein.
Nature 1986;319(6050):226-30.
1986: Hung M C; Schechter A L; Chevray P Y; Stern D F; Weinberg R A
Molecular cloning of the neu gene: absence of gross structural alteration in oncogenic alleles.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):261-4.
1986: Drebin J A; Link V C; Stern D F; Weinberg R A; Greene M I
Development of monoclonal antibodies reactive with the product of the neu oncogene.
Symposium on Fundamental Cancer Research 1986;38():277-89.
1986: Dryja T P; Friend S; Weinberg R A
Genetic sequences that predispose to retinoblastoma and osteosarcoma.
Symposium on Fundamental Cancer Research 1986;39():115-9.
1985: Dotto G P; Parada L F; Weinberg R A
Specific growth response of ras-transformed embryo fibroblasts to tumour promoters.
Nature 1985;318(6045):472-5.
1985: Weinberg R A
The action of oncogenes in the cytoplasm and nucleus.
Science (New York, N.Y.) 1985;230(4727):770-6.
1985: Schechter A L; Hung M C; Vaidyanathan L; Weinberg R A; Yang-Feng T L; Francke U; Ullrich A; Coussens L
The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor.
Science (New York, N.Y.) 1985;229(4717):976-8.
1985: Chipperfield R G; Jones S S; Lo K M; Weinberg R A
Activation of Ha-ras p21 by substitution, deletion, and insertion mutations.
Molecular and cellular biology 1985;5(8):1809-13.
1985: Drebin J A; Link V C; Stern D F; Weinberg R A; Greene M I
Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies.
Cell 1985;41(3):697-706.
1985: Bernstein S C; Weinberg R A
Expression of the metastatic phenotype in cells transfected with human metastatic tumor DNA.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(6):1726-30.
1985: Tabin C J; Weinberg R A
Analysis of viral and somatic activations of the cHa-ras gene.
Journal of virology 1985;53(1):260-5.
1985: Cunningham J M; Weinberg R A
Ras oncogenes in human tumours: identification, mechanism of activation and cooperative role in transformation.
IARC scientific publications 1985;(60):359-64.
1985: Parada L F; Land H; Chen A; Morganstern J; Weinberg R A
Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts.
Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progrès en virologie médicale 1985;32():115-28.
1984: Drebin J A; Stern D F; Link V C; Weinberg R A; Greene M I
Monoclonal antibodies identify a cell-surface antigen associated with an activated cellular oncogene.
Nature 1984;312(5994):545-8.
1984: Weinberg R A
ras Oncogenes and the molecular mechanisms of carcinogenesis.
Blood 1984;64(6):1143-5.
1984: Parada L F; Land H; Weinberg R A; Wolf D; Rotter V
Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation.
Nature 1984;312(5995):649-51.
1984: Schechter A L; Stern D F; Vaidyanathan L; Decker S J; Drebin J A; Greene M I; Weinberg R A
The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen.
Nature 1984;312(5994):513-6.
1984: McCoy M S; Bargmann C I; Weinberg R A
Human colon carcinoma Ki-ras2 oncogene and its corresponding proto-oncogene.
Molecular and cellular biology 1984;4(8):1577-82.
1984: Weinberg R A
Oncogenes and the molecular basis of cancer.
Harvey lectures 1984;80():129-36.
1984: Lenoir G M; Land H; Parada L F; Cunningham J M; Weinberg R A
Activated oncogenes in Burkitt's lymphoma.
Current topics in microbiology and immunology 1984;113():6-14.
1983: Weinberg R A
Oncogenes and the molecular biology of cancer.
The Journal of cell biology 1983;97(6):1661-2.
1983: Parada L F; Weinberg R A
Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene.
Molecular and cellular biology 1983;3(12):2298-301.
1983: Weinberg R A
A molecular basis of cancer.
Scientific American 1983;249(5):126-42.
1983: Land H; Parada L F; Weinberg R A
Cellular oncogenes and multistep carcinogenesis.
Science (New York, N.Y.) 1983;222(4625):771-8.
1983: Barker D; McCoy M; Weinberg R; Goldfarb M; Wigler M; Burt R; Gardner E; White R
A test of the role of two oncogenes in inherited predisposition to colon cancer.
Molecular biology & medicine 1983;1(2):199-206.
1983: Weinberg R A
Oncogenes.
CA: a cancer journal for clinicians 1983;33(5):300-6.
1983: Land H; Parada L F; Weinberg R A
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes.
Nature 1983;304(5927):596-602.
1983: Murray M J; Cunningham J M; Parada L F; Dautry F; Lebowitz P; Weinberg R A
The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors.
Cell 1983;33(3):749-57.
1983: Weinberg R A
Retroviruses and human disease.
Hospital practice (Office ed.) 1983;18(7):13, 17-8.
1983: Weinberg R A
Alteration of the genomes of tumor cells.
Cancer 1983;51(11):1971-5.
1983: Sakaguchi A Y; Naylor S L; Shows T B; Toole J J; McCoy M; Weinberg R A
Human c-Ki-ras2 proto-oncogene on chromosome 12.
Science (New York, N.Y.) 1983;219(4588):1081-3.
1983: McCoy M S; Toole J J; Cunningham J M; Chang E H; Lowy D R; Weinberg R A
Characterization of a human colon/lung carcinoma oncogene.
Nature 1983;302(5903):79-81.
1983: de Martinville B; Giacalone J; Shih C; Weinberg R A; Francke U
Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11.
Science (New York, N.Y.) 1983;219(4584):498-501.
1983: Murray M J; Kaufman R J; Latt S A; Weinberg R A
Construction and use of a dominant, selectable marker: a Harvey sarcoma virus-dihydrofolate reductase chimera.
Molecular and cellular biology 1983;3(1):32-43.
1983: Parada L F; Shih C; Murray M; Weinberg R A
The oncogene of a human bladder carcinoma.
Progress in nucleic acid research and molecular biology 1983;29():269-72.
1983: Weinberg R A
Transforming genes of tumor cells.
International review of cytology. Supplement 1983;15():191-202.
1982: Tabin C J; Bradley S M; Bargmann C I; Weinberg R A; Papageorge A G; Scolnick E M; Dhar R; Lowy D R; Chang E H
Mechanism of activation of a human oncogene.
Nature 1982;300(5888):143-9.
1982: Hoffmann J W; Steffen D; Gusella J; Tabin C; Bird S; Cowing D; Weinberg R A
DNA methylation affecting the expression of murine leukemia proviruses.
Journal of virology 1982;44(1):144-57.
1982: Weinberg R A
Fewer and fewer oncogenes.
Cell 1982;30(1):3-4.
1982: Parada L F; Tabin C J; Shih C; Weinberg R A
Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene.
Nature 1982;297(5866):474-8.
1982: Shih C; Weinberg R A
Isolation of a transforming sequence from a human bladder carcinoma cell line.
Cell 1982;29(1):161-9.
1982: Padhy L C; Shih C; Cowing D; Finkelstein R; Weinberg R A
Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas.
Cell 1982;28(4):865-71.
1982: Steffen D L; Taylor B A; Weinberg R A
Continuing germ line integration of AKV proviruses during the breeding of AKR mice and derivative recombinant inbred strains.
Journal of virology 1982;42(1):165-75.
1982: Tabin C J; Hoffmann J W; Goff S P; Weinberg R A
Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene.
Molecular and cellular biology 1982;2(4):426-36.
1982: Goff S P; Tabin C J; Wang J Y; Weinberg R; Baltimore D
Transfection of fibroblasts by cloned Abelson murine leukemia virus DNA and recovery of transmissible virus by recombination with helper virus.
Journal of virology 1982;41(1):271-85.
1982: Weinberg R A
Oncogenes of spontaneous and chemically induced tumors.
Advances in cancer research 1982;36():149-63.
1981: Coffin J M; Varmus H E; Bishop J M; Essex M; Hardy W D; Martin G S; Rosenberg N E; Scolnick E M; Weinberg R A; Vogt P K
Proposal for naming host cell-derived inserts in retrovirus genomes.
Journal of virology 1981;40(3):953-7.
1981: Shilo B Z; Weinberg R A
DNA sequences homologous to vertebrate oncogenes are conserved in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(11):6789-92.
1981: Murray M J; Shilo B Z; Shih C; Cowing D; Hsu H W; Weinberg R A
Three different human tumor cell lines contain different oncogenes.
Cell 1981;25(2):355-61.
1981: Weinberg R A
Use of transfection to analyze genetic information and malignant transformation.
Biochimica et biophysica acta 1981;651(1):25-35.
1981: Weinberg R A; Steffen D L
Regulation of expression of the integrated retrovirus genome.
The Journal of general virology 1981;54(Pt 1):1-8.
1981: Goldfarb M P; Weinberg R A
Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination.
Journal of virology 1981;38(1):136-50.
1981: Goldfarb M P; Weinberg R A
Structure of the provirus within NIH 3T3 cells transfected with Harvey sarcoma virus DNA.
Journal of virology 1981;38(1):125-35.
1981: Shih C; Padhy L C; Murray M; Weinberg R A
Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts.
Nature 1981;290(5803):261-4.
1981: Shilo B Z; Weinberg R A
Unique transforming gene in carcinogen-transformed mouse cells.
Nature 1981;289(5798):607-9.
1980: Weinberg R A
Origins and roles of endogenous retroviruses.
Cell 1980;22(3):643-4.
1980: Steffen D L; Bird S; Weinberg R A
Evidence for the Asiatic origin of endogenous AKR-type murine leukemia proviruses.
Journal of virology 1980;35(3):824-35.
1980: Donoghue D J; Goldfarb M P; Sharp P A; Weinberg R A
Organization of murine sarcoma virus genomes.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 2,():721-6.
1980: Weinberg R A
Integrated genomes of animal viruses.
Annual review of biochemistry 1980;49():197-226.
1979: Donoghue D J; Sharp P A; Weinberg R A
Comparative study of different isolates of murine sarcoma virus.
Journal of virology 1979;32(3):1015-27.
1979: Shih C; Shilo B Z; Goldfarb M P; Dannenberg A; Weinberg R A
Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(11):5714-8.
1979: Goldfarb M P; Weinberg R A
Physical map of biologically active Harvey sarcoma virus unintegrated linear DNA.
Journal of virology 1979;32(1):30-9.
1979: Steffen D; Bird S; Rowe W P; Weinberg R A
Identification of DNA fragments carrying ecotropic proviruses of AKR mice.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(9):4554-8.
1979: Donoghue D J; Sharp P A; Weinberg R A
An MSV-specific subgenomic mRNA in MSV-transformed G8-124 cells.
Cell 1979;17(1):53-63.
1979: Yoshimura F K; Weinberg R A
Restriction endonuclease cleavage of linear and closed circular murine leukemia viral DNAs: discovery of a smaller circular form.
Cell 1979;16(2):323-32.
1979: Andersson P; Goldfarb M P; Weinberg R A
A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection.
Cell 1979;16(1):63-75.
1979: Steffen D; Andersson P; Goldfarb M; Weinberg R A
Integration and possible transduction by retroviruses.
Cold Spring Harbor symposia on quantitative biology 1979;43 Pt 2():875-9.
1978: Steffen D; Weinberg R A
The integrated genome of murine leukemia virus.
Cell 1978;15(3):1003-10.
1978: Philipson L; Andersson P; Olshevsky U; Weinberg R; Baltimore D; Gesteland R
Translation of MuLV and MSV RNAs in nuclease-treated reticulocyte extracts: enhancement of the gag-pol polypeptide with yeast suppressor tRNA.
Cell 1978;13(1):189-99.
1977: Rothenberg E; Smotkin D; Baltimore D; Weinberg R A
In vitro synthesis of infectious DNA of murine leukaemia virus.
Nature 1977;269(5624):122-6.
1977: Weinberg R A
How does T antigen transform cells?
Cell 1977;11(2):243-6.
1977: Weinberg R A
Structure of the intermediates leading to the integrated provirus.
Biochimica et biophysica acta 1977;473(1):39-55.
1976: Smotkin D; Yoshimura F K; Weinberg R A
Infectious, linear, unintegrated DNA of Moloney murine leukemia virus.
Journal of virology 1976;20(3):621-6.
1976: Gianni A M; Hutton J R; Smotkin D; Weinberg R A
Proviral DNA of Moloney leukemia virus: purification and visualization.
Science (New York, N.Y.) 1976;191(4227):569-71.
1975: Smotkin D; Gianni A M; Rozenblatt S; Weinberg R A
Infectious viral DNA of murine leukemia virus.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(12):4910-3.
1975: Paskind M P; Weinberg R A; Baltimore D
Dependence of Moloney murine leukemia virus production on cell growth.
Virology 1975;67(1):242-8.
1975: Gianni A M; Weinberg R A
Partially single-stranded form of free Moloney viral DNA.
Nature 1975;255(5510):646-8.
1975: Gianni A M; Smotkin D; Weinberg R A
Murine leukemia virus: detection of unintegrated double-stranded DNA forms of the provirus.
Proceedings of the National Academy of Sciences of the United States of America 1975;72(2):447-51.
1975: Besmer P; Smotkin D; Haseltine W; Fan H; Wilson A T; Paskind M; Weinberg R; Baltimore D
Mechanism of induction of RNA tumor viruses by halogenated pyrimidines.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 2():1103-7.
1975: Weinberg R A; Newbold J E
Mapping of SV40 mRNA species on the viral genome.
Cold Spring Harbor symposia on quantitative biology 1975;39 Pt 1():161-4.
1974: Weinberg R A; Ben-Ishai Z; Newbold J E
Simian virus 40 transcription in productively infected and transformed cells.
Journal of virology 1974;13(6):1263-73.
1974: Lodish H F; Weinberg R; Ozer H L
Translation of mRNA from simian virus 40-infected cells into simian virus 40 capsid protein by cell-free extracts.
Journal of virology 1974;13(3):590-5.
1973: Leibowitz R D; Weinberg R A; Penman S
Unusual metabolism of 5 S RNA in HeLa cells.
Journal of molecular biology 1973;73(1):139-44.
1973: Weinberg R A
Nuclear RNA metabolism.
Annual review of biochemistry 1973;42():329-54.
1972: Weinberg R A; Warnaar S O; Winocour E
Isolation and characterization of simian virus 40 ribonucleic acid.
Journal of virology 1972;10(2):193-201.
1972: Weinberg R A; Ben-Ishai Z; Newbold J E
Poly A associated with SV40 messenger RNA.
Nature: New biology 1972;238(82):111-3.
1970: Weinberg R A; Penman S
Processing of 45 s nucleolar RNA.
Journal of molecular biology 1970;47(2):169-78.
1969: Weinberg R; Penman S
Metabolism of small molecular weight monodisperse nuclear RNA.
Biochimica et biophysica acta 1969;190(1):10-29.
1969: Siev M; Weinberg R; Penman S
The selective interruption of nucleolar RNA synthesis in HeLa cells by cordycepin.
The Journal of cell biology 1969;41(2):510-20.
1969: Penman S; Vesco C; Weinberg R; Zylber E
The RNA metabolism of nucleoli and mitochondria in mammalian cells.
Cold Spring Harbor symposia on quantitative biology 1969;34():535-46.
1968: Weinberg R A; Penman S
Small molecular weight monodisperse nuclear RNA.
Journal of molecular biology 1968;38(3):289-304.
1967: Weinberg R A; Loening U; Willems M; Penman S
Acrylamide gel electrophoresis of HeLa cell nucleolar RNA.
Proceedings of the National Academy of Sciences of the United States of America 1967;58(3):1088-95.

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