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Giangiacomo Torri

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Derek J Langeslay; Annamaria Naggi; Giangiacomo Torri; Elena Urso; Cristina Gardini; Cynthia K Larive
Reversed-phase ion-pair ultra-high-performance-liquid chromatography-mass spectrometry for fingerprinting low-molecular-weight heparins.
Anna Alekseeva; Benito Casu; Sabrina Pierro; Giangiacomo Torri; Annamaria Naggi
Profiling glycol-split heparins by high-performance liquid chromatography/mass spectrometry analysis of their heparinase-generated oligosaccharides.
Derek J Langeslay; Consuelo N Beecher; Marco Guerrini; Annamaria Naggi; Giangiacomo Torri; Cynthia K Larive
Characterizing the microstructure of heparin and heparan sulfate using N-sulfoglucosamine 1H and 15N NMR chemical shift analysis.

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2013: Derek J Langeslay; Annamaria Naggi; Giangiacomo Torri; Elena Urso; Cristina Gardini; Cynthia K Larive
Reversed-phase ion-pair ultra-high-performance-liquid chromatography-mass spectrometry for fingerprinting low-molecular-weight heparins.
Journal of chromatography. A 2013;1292():201-10.
2013: Anna Alekseeva; Benito Casu; Sabrina Pierro; Giangiacomo Torri; Annamaria Naggi
Profiling glycol-split heparins by high-performance liquid chromatography/mass spectrometry analysis of their heparinase-generated oligosaccharides.
Analytical biochemistry 2013;434(1):112-22.
2013: Derek J Langeslay; Consuelo N Beecher; Marco Guerrini; Annamaria Naggi; Giangiacomo Torri; Cynthia K Larive
Characterizing the microstructure of heparin and heparan sulfate using N-sulfoglucosamine 1H and 15N NMR chemical shift analysis.
Analytical chemistry 2013;85(2):1247-55.
2013: marco Guerrini; Pierre Mourier; Timothy R Rudd; Giangiacomo Torri; Christian Boudier; Benito Casu; Stefano Elli; Davide Gaudesi; Christian Viskov
An unusual antithrombin-binding heparin octasaccharide with an additional 3-O-sulfated glucosamine in the active pentasaccharide sequence.
The Biochemical journal 2013;449(2):343-51.
2012: Timothy R Rudd; Edwin A Yates; Cristina Gardini; Marco Guerrini; Eleonora Macchi; Laura Muzi; Giangiacomo Torri
How to find a needle (or anything else) in a haystack: two-dimensional correlation spectroscopy-filtering with iterative random sampling applied to pharmaceutical heparin.
Analytical chemistry 2012;84(15):6841-7.
2012: Martin Schlesinger; Patrick Schmitz; Giangiacomo Torri; Reiner Zeisig; Benito Casu; Annamaria Naggi; Gerd Bendas
The inhibition of the integrin VLA-4 in MV3 melanoma cell binding by non-anticoagulant heparin derivatives.
Thrombosis research 2012;129(5):603-10.
2012: Alessandro Parra; Lucia Martini; Noemi Veraldi; Milena Fini; Luca Sangiorgi; Giangiacomo Torri; Manuela Locatelli; Antonella Bisio
Heparin-like heparan sulfate from rabbit cartilage.
Glycobiology 2012;22(2):248-57.
2012: Elena Vismara; Alessia Coletti; Annamaria Naggi; Elena Urso; Antonio Valerio; Giangiacomo Torri
Anti-metastatic semi-synthetic sulfated maltotriose C-C linked dimers. Synthesis and characterisation.
Molecules (Basel, Switzerland) 2012;17(8):9912-30.
2011: Magdalena Bacilieri; Monica Ceol; Maura Comoli; Stefano Moro; Annamaria Naggi; Manlio Palumbo; Erwin D Schleicher; Giangiacomo Torri; Enrica Tosetto; Giovanni Gambaro
Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor-β1 expression in mesangial cells: biochemical and structural considerations.
Glycobiology 2011;21(8):1029-37.
2011: Guilherme L Sassaki; Daniel S Riter; Arquimedes P Santana Filho; Marco Guerrini; Marcelo A Lima; Cesare Cosentino; lauro souza; Thales R Cipriani; Tim Rudd; Helena B Nader; Edwin A Yates; Philip A J Gorin; Giangiacomo Torri; Marcello Iacomini
A robust method to quantify low molecular weight contaminants in heparin: detection of tris(2-n-butoxyethyl) phosphate.
The Analyst 2011;136(11):2330-8.
2011: Angelo Alberti; Piergiorgio Fuochi; Maurizio Guerra; Dante Macciantelli; Giangiacomo Torri; Antonio Valerio; Elena Vismara
Radical-based grafting of GMA on sutures of different nature.
Organic & biomolecular chemistry 2011;9(9):3199-204.
2011: Lubor Borsig; Israel Vlodavsky; Rivka Ishai-Michaeli; Giangiacomo Torri; Elena Vismara
Sulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanase.
Neoplasia (New York, N.Y.) 2011;13(5):445-52.
2011: Tim Rudd; Davide Gaudesi; Marcelo A Lima; Mark A Skidmore; Barbara Mulloy; Giangiacomo Torri; Helena B Nader; marco Guerrini; Edwin A Yates
High-sensitivity visualisation of contaminants in heparin samples by spectral filtering of 1H NMR spectra.
The Analyst 2011;136(7):1390-8.
2011: Tim Rudd; Davide Gaudesi; Mark A Skidmore; Monica Ferro; marco Guerrini; Barbara Mulloy; Giangiacomo Torri; Edwin A Yates
Construction and use of a library of bona fide heparins employing 1H NMR and multivariate analysis.
The Analyst 2011;136(7):1380-9.
2011: Joseph P Ritchie; Vishnu C Ramani; Yongsheng Ren; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Sergio Penco; Claudio Pisano; Paolo Carminati; Monica Tortoreto; Franco Zunino; Israel Vlodavsky; Ralph D Sanderson; Yang Yang
SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(6):1382-93.
2010: Tim Rudd; Katarzyna A Uniewicz; Alessandro Ori; Scott E Guimond; Mark A Skidmore; Davide Gaudesi; Ruoyan Xu; Jeremy E Turnbull; marco Guerrini; Giangiacomo Torri; Giuliano Siligardi; Mark C Wilkinson; David G Fernig; Edwin A Yates
Comparable stabilisation, structural changes and activities can be induced in FGF by a variety of HS and non-GAG analogues: implications for sequence-activity relationships.
Organic & biomolecular chemistry 2010;8(23):5390-7.
2010: marco Guerrini; Stefano Elli; Davide Gaudesi; Giangiacomo Torri; Benito Casu; Pierre Mourier; Frederic Herman; Christian Boudier; Martin Lorenz; Christian Viskov
Effects on molecular conformation and anticoagulant activities of 1,6-anhydrosugars at the reducing terminal of antithrombin-binding octasaccharides isolated from low-molecular-weight heparin enoxaparin.
Journal of medicinal chemistry 2010;53(22):8030-40.
2010: M Schlesinger; A Naggi; Giangiacomo Torri; R Zeisig; M Alexander; P Schmitz; B Casu; G Bendas
Blocking of integrin-mediated human MV3 melanoma cell binding by commercial and modified heparins.
International journal of clinical pharmacology and therapeutics 2010;48(7):448-50.
2010: Benito Casu; Annamaria Naggi; Giangiacomo Torri
Heparin-derived heparan sulfate mimics to modulate heparan sulfate-protein interaction in inflammation and cancer.
Matrix biology : journal of the International Society for Matrix Biology 2010;29(6):442-52.
2010: Elena Vismara; Monica Pierini; Giuseppe Mascellani; Lino Liverani; Marcelo Lima; Marco Guerrini; Giangiacomo Torri
Low-molecular-weight heparin from Cu2+ and Fe2+ Fenton type depolymerisation processes.
Thrombosis and haemostasis 2010;103(3):613-22.
2009: marco Guerrini; Zachary Shriver; Antonella Bisio; Annamaria Naggi; Benito Casu; Ram Sasisekharan; Giangiacomo Torri
The tainted heparin story: an update.
Thrombosis and haemostasis 2009;102(5):907-11.
2009: Antonella Bisio; Davide Vecchietti; Laura Citterio; marco Guerrini; Rahul Raman; Sabrina Bertini; Giorgio Eisele; Annamaria Naggi; Ram Sasisekharan; Giangiacomo Torri
Structural features of low-molecular-weight heparins affecting their affinity to antithrombin.
Thrombosis and haemostasis 2009;102(5):865-73.
2009: Elena Vismara; Lucio Melone; Giuseppe Gastaldi; Cesare Cosentino; Giangiacomo Torri
Surface functionalization of cotton cellulose with glycidyl methacrylate and its application for the adsorption of aromatic pollutants from wastewaters.
Journal of hazardous materials 2009;170(2-3):798-808.
2009: marco Guerrini; Zhenqing Zhang; Zachary Shriver; Annamaria Naggi; Sayaka Masuko; Robert Langer; Benito Casu; Robert J Linhardt; Giangiacomo Torri; Ram Sasisekharan
Orthogonal analytical approaches to detect potential contaminants in heparin.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(40):16956-61.
2009: Gleb Zilberstein; Ilya Shlar; Leonid Korol; Emmanuil Baskin; Elisa Fasoli; Pier Giorgio Righetti; Giangiacomo Torri; Antonella Bisio; Shmuel Bukshpan
Focusing of low-molecular-mass heparins in polycationic polyacrylamide matrices.
Analytical chemistry 2009;81(16):6966-71.
2009: Angelo Alberti; Dante Macciantelli; Annamaria Naggi; Elena Urso; Giangiacomo Torri; Elena Vismara
Electrochemical characterisation of 6-iodomaltose, 6'-iodomaltose and 6-iodomaltotriose on a silver cathode and their one-pot electrochemical dimerisation to new mixed O/C maltotetraose and maltohexaose mimics.
Chemistry (Weinheim an der Bergstrasse, Germany) 2009;15(32):8005-14.
2009: Scott E Guimond; Tim Rudd; Mark A Skidmore; Alessandro Ori; Davide Gaudesi; Cesare Cosentino; marco Guerrini; Ruth Edge; David Collison; Eric McInnes; Giangiacomo Torri; Jeremy E Turnbull; David G Fernig; Edwin A Yates
Cations modulate polysaccharide structure to determine FGF-FGFR signaling: a comparison of signaling and inhibitory polysaccharide interactions with FGF-1 in solution.
Biochemistry 2009;48(22):4772-9.
2009: Tim Rudd; Mark A Skidmore; Scott E Guimond; Cesare Cosentino; Giangiacomo Torri; David G Fernig; Robert Lauder; marco Guerrini; Edwin A Yates
Glycosaminoglycan origin and structure revealed by multivariate analysis of NMR and CD spectra.
Glycobiology 2009;19(1):52-67.
2008: Sara Guglier; Milos Hricovíni; Rahul Raman; Laura Polito; Giangiacomo Torri; Benito Casu; Ram Sasisekharan; marco Guerrini
Minimum FGF2 binding structural requirements of heparin and heparan sulfate oligosaccharides as determined by NMR spectroscopy.
Biochemistry 2008;47(52):13862-9.
2008: Fhernanda Ribeiro Smiderle; L M Olsen; Elaine R Carbonero; R Marcon; Cristiane Hatsuko Baggio; Cristina Setim Freitas; Adair R S Santos; Giangiacomo Torri; Philip A J Gorin; Marcello Iacomini
A 3-O-methylated mannogalactan from Pleurotus pulmonarius: structure and antinociceptive effect.
Phytochemistry 2008;69(15):2731-6.
2008: marco Guerrini; Sara Guglieri; Benito Casu; Giangiacomo Torri; Pierre Mourier; Christian Boudier; Christian Viskov
Antithrombin-binding octasaccharides and role of extensions of the active pentasaccharide sequence in the specificity and strength of interaction. Evidence for very high affinity induced by an unusual glucuronic acid residue.
The Journal of biological chemistry 2008;283(39):26662-75.
2008: Tim Rudd; Mark A Skidmore; Scott E Guimond; marco Guerrini; Cesare Cosentino; R Edge; A Brown; D T Clarke; Giangiacomo Torri; Jeremy E Turnbull; Richard J Nichols; David G Fernig; Edwin A Yates
Site-specific interactions of copper(II) ions with heparin revealed with complementary (SRCD, NMR, FTIR and EPR) spectroscopic techniques.
Carbohydrate research 2008;343(12):2184-93.
2008: marco Guerrini; Daniela Beccati; Zachary Shriver; Annamaria Naggi; Karthik Viswanathan; Antonella Bisio; Ishan Capila; Jonathan C. Lansing; Sara Guglieri; Blair Fraser; Ali Al-Hakim; Nur Sibel Gunay; Zhenqing Zhang; Luke Robinson; Lucinda Buhse; Moheb Nasr; Janet Woodcock; Robert Langer; Ganesh Venkataraman; Robert J Linhardt; Benito Casu; Giangiacomo Torri; Ram Sasisekharan
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events.
Nature biotechnology 2008;26(6):669-75.
2008: Silvia Salati; Fabrizio Adani; Cesare Cosentino; Giangiacomo Torri
Studying soil organic matter using 13C CP-MAS NMR: the effect of soil chemical pre-treatments on spectra quality and representativity.
Chemosphere 2008;70(11):2092-8.
2008: Elaine R Carbonero; Ana Helena P Gracher; Moira Caroline C Rosa; Giangiacomo Torri; Guilherme L Sassaki; Philip A J Gorin; Marcello Iacomini
Unusual partially 3-O-methylated alpha-galactan from mushrooms of the genus Pleurotus.
Phytochemistry 2008;69(1):252-7.
2007: Nina Hostettler; Annamaria Naggi; Giangiacomo Torri; Rivka Ishai-Michaeli; Benito Casu; Israel Vlodavsky; Lubor Borsig
P-selectin- and heparanase-dependent antimetastatic activity of non-anticoagulant heparins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(13):3562-72.
2007: Yang Yang; Veronica MacLeod; Yuemeng Dai; Yekaterina Khotskaya-Sample; Zachary Shriver; Ganesh Venkataraman; Ram Sasisekharan; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Israel Vlodavsky; Larry J Suva; Joshua Epstein; Shmuel Yaccoby; John D Shaughnessy; Bart Barlogie; Ralph D Sanderson
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.
Blood 2007;110(6):2041-8.
2007: Tim Rudd; Scott E Guimond; Mark A Skidmore; Laurence Duchesne; marco Guerrini; Giangiacomo Torri; Cesare Cosentino; Alan Brown; David T Clarke; Jeremy E Turnbull; David G Fernig; Edwin A Yates
Influence of substitution pattern and cation binding on conformation and activity in heparin derivatives.
Glycobiology 2007;17(9):983-93.
2007: Marjut Borgenström; Anni Wärri; Katri Hiilesvuo; Rami Käkönen; Sanna Käkönen; Liisa Nissinen; Marjo Pihlavisto; Anne Marjamäki; Israel Vlodavsky; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Timo Veromaa; Markku Salmivirta; Klaus Elenius
O-sulfated bacterial polysaccharides with low anticoagulant activity inhibit metastasis.
Seminars in thrombosis and hemostasis 2007;33(5):547-56.
2007: Antonella Bisio; Alessandra Mantegazza; Elena Urso; Annamaria Naggi; Giangiacomo Torri; Christian Viskov; Benito Casu
High-performance liquid chromatographic/mass spectrometric studies on the susceptibility of heparin species to cleavage by heparanase.
Seminars in thrombosis and hemostasis 2007;33(5):488-95.
2007: marco Guerrini; Sara Guglieri; Annamaria Naggi; Ram Sasisekharan; Giangiacomo Torri
Low molecular weight heparins: structural differentiation by bidimensional nuclear magnetic resonance spectroscopy.
Seminars in thrombosis and hemostasis 2007;33(5):478-87.
2007: Elena Vismara; Monica Pierini; Sara Guglieri; Lino Liverani; Giuseppe Mascellani; Giangiacomo Torri
Structural modification induced in heparin by a Fenton-type depolymerization process.
Seminars in thrombosis and hemostasis 2007;33(5):466-77.
2007: Giuseppe Mascellani; marco Guerrini; Giangiacomo Torri; Lino Liverani; Franco Spelta; Pietro Bianchini
Characterization of di- and monosulfated, unsaturated heparin disaccharides with terminal N-sulfated 1,6-anhydro-beta-D-glucosamine or N-sulfated 1,6-anhydro-beta-D-mannosamine residues.
Carbohydrate research 2007;342(6):835-42.
2007: Israel Vlodavsky; Neta Ilan; Yona Nadir; Benjamin Brenner; Ben-Zion Katz; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Ram Sasisekharan
Heparanase, heparin and the coagulation system in cancer progression.
Thrombosis research 2007;120 Suppl 2():S112-20.
2007: marco Guerrini; Milos Hricovíni; Giangiacomo Torri
Interaction of heparins with fibroblast growth factors: conformational aspects.
Current pharmaceutical design 2007;13(20):2045-56.
2006: marco Guerrini; Sara Guglieri; Daniela Beccati; Giangiacomo Torri; Christian Viskov; Pierre Mourier
Conformational transitions induced in heparin octasaccharides by binding with antithrombin III.
The Biochemical journal 2006;399(2):191-8.
2006: Claudia Sissi; Lorena Lucatello; Annamaria Naggi; Giangiacomo Torri; Manlio Palumbo
Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G.
Biochemical pharmacology 2006;71(3):287-93.
2005: Annamaria Naggi; Benito Casu; Marta Perez; Giangiacomo Torri; Giuliana Cassinelli; Sergio Penco; Claudio Pisano; Giuseppe Giannini; Rivka Ishai-Michaeli; Israel Vlodavsky
Modulation of the heparanase-inhibiting activity of heparin through selective desulfation, graded N-acetylation, and glycol splitting.
The Journal of biological chemistry 2005;280(13):12103-13.
2005: marco Guerrini; Annamaria Naggi; Sara Guglieri; Roberto Santarsiero; Giangiacomo Torri
Complex glycosaminoglycans: profiling substitution patterns by two-dimensional nuclear magnetic resonance spectroscopy.
Analytical biochemistry 2005;337(1):35-47.
2005: Claudio Pisano; Concetta Aulicino; Loredana Vesci; Benito Casu; Annamaria Naggi; Giangiacomo Torri; Dragana Vukasovic; Mirella Belleri; MARCO RUSNATI; Marco Presta
Undersulfated, low-molecular-weight glycol-split heparin as an antiangiogenic VEGF antagonist.
Glycobiology 2005;15(2):1C-6C.
2005: Ulf Lindahl; Jin-Ping Li; Marion Kusche-Gullberg; Markku Salmivirta; Sakari Alaranta; Timo Veromaa; Jef J Emeis; Ian Roberts; Clare Taylor; Pasqua Oreste; Giorgio Zoppetti; Annamaria Naggi; Giangiacomo Torri; Benito Casu
Generation of "neoheparin" from E. coli K5 capsular polysaccharide.
Journal of medicinal chemistry 2005;48(2):349-52.
2005: Sabrina Bertini; Antonella Bisio; Giangiacomo Torri; Donata Bensi; Maria Terbojevich
Molecular weight determination of heparin and dermatan sulfate by size exclusion chromatography with a triple detector array.
Biomacromolecules 2005;6(1):168-73.
2004: Benito Casu; marco Guerrini; Sara Guglieri; Annamaria Naggi; Marta Perez; Giangiacomo Torri; Giuliana Cassinelli; Dragana Vukasovic; Paolo Carminati; Giuseppe Giannini; Sergio Penco; Claudio Pisano; Mirella Belleri; MARCO RUSNATI; Marco Presta
Undersulfated and glycol-split heparins endowed with antiangiogenic activity.
Journal of medicinal chemistry 2004;47(4):838-48.
2004: Benito Casu; marco Guerrini; Giangiacomo Torri
Structural and conformational aspects of the anticoagulant and anti-thrombotic activity of heparin and dermatan sulfate.
Current pharmaceutical design 2004;10(9):939-49.
2003: Claudia Sissi; Annamaria Naggi; Giangiacomo Torri; Manlio Palumbo
Modulation of antithrombin-protease interactions by semisynthetic low-molecular-weight heparins with different sulfation patterns.
Seminars in thrombosis and hemostasis 2003;29(6):661-70.
2002: marco Guerrini; Rahul Raman; Ganesh Venkataraman; Giangiacomo Torri; Ram Sasisekharan; Benito Casu
A novel computational approach to integrate NMR spectroscopy and capillary electrophoresis for structure assignment of heparin and heparan sulfate oligosaccharides.
Glycobiology 2002;12(11):713-9.
2002: Benito Casu; marco Guerrini; Annamaria Naggi; Marta Perez; Giangiacomo Torri; Dragana Vukasovic; Paolo Carminati; Giuseppe Giannini; Sergio Penco; Claudio Pisano; Mirella Belleri; MARCO RUSNATI; Marco Presta
Short heparin sequences spaced by glycol-split uronate residues are antagonists of fibroblast growth factor 2 and angiogenesis inhibitors.
Biochemistry 2002;41(33):10519-28.
2002: Claudia Sissi; Lorena Lucatello; Annamaria Naggi; Giangiacomo Torri; Manlio Palumbo
Effects of calcium ions on the interactions between antithrombin and factor Xa mediated by variously sulfated, semisynthetic low-molecular-weight heparins.
Seminars in thrombosis and hemostasis 2002;28(4):355-60.
2002: Job Harenberg; Benito Casu; marco Guerrini; Reinhard Malsch; Annamaria Naggi; Lukas Piazolo; Giangiacomo Torri
Low-molecular-weight heparin and dermatan sulfate end group-labeled with tyramine and fluorescein. Biochemical and biological characterization of the fluorescent-labeled heparin derivative.
Seminars in thrombosis and hemostasis 2002;28(4):343-54.
2002: Benito Casu; Annamaria Naggi; Giangiacomo Torri
Chemical derivatization as a strategy to study structure-activity relationships of glycosaminoglycans.
Seminars in thrombosis and hemostasis 2002;28(4):335-42.
2002: Milos Hricovíni; marco Guerrini; Antonella Bisio; Giangiacomo Torri; Annamaria Naggi; Benito Casu
Active conformations of glycosaminoglycans. NMR determination of the conformation of heparin sequences complexed with antithrombin and fibroblast growth factors in solution.
Seminars in thrombosis and hemostasis 2002;28(4):325-34.
2002: marco Guerrini; Teresa Agulles; Antonella Bisio; Milos Hricovini; Luigi Lay; Annamaria Naggi; Laura Poletti; Luisella Sturiale; Giangiacomo Torri; Benito Casu
Minimal heparin/heparan sulfate sequences for binding to fibroblast growth factor-1.
Biochemical and biophysical research communications 2002;292(1):222-30.
2001: Annamaria Naggi; B De Cristofano; Antonella Bisio; Giangiacomo Torri; Benito Casu
Generation of anti-factor Xa active, 3-O-sulfated glucosamine-rich sequences by controlled desulfation of oversulfated heparins.
Carbohydrate research 2001;336(4):283-90.
2001: Milos Hricovíni; marco Guerrini; Antonella Bisio; Giangiacomo Torri; Maurice Petitou; Benito Casu
Conformation of heparin pentasaccharide bound to antithrombin III.
The Biochemical journal 2001;359(Pt 2):265-72.
2001: Antonella Bisio; L De Ambrosi; S Gonella; marco Guerrini; Sara Guglieri; G Maggia; Giangiacomo Torri
Preserving the original heparin structure of a novel low molecular weight heparin by gamma-irradiation.
Arzneimittel-Forschung 2001;51(10):806-13.
2001: Claudia Sissi; Annamaria Naggi; Giangiacomo Torri; Manlio Palumbo
Effects of sulfation on antithrombin-thrombin/factor Xa interactions in semisynthetic low molecular weight heparins.
Seminars in thrombosis and hemostasis 2001;27(5):483-7.
2001: marco Guerrini; Antonella Bisio; Giangiacomo Torri
Combined quantitative (1)H and (13)C nuclear magnetic resonance spectroscopy for characterization of heparin preparations.
Seminars in thrombosis and hemostasis 2001;27(5):473-82.
2001: Luisella Sturiale; Annamaria Naggi; Giangiacomo Torri
MALDI mass spectrometry as a tool for characterizing glycosaminoglycan oligosaccharides and their interaction with proteins.
Seminars in thrombosis and hemostasis 2001;27(5):465-72.
2001: Annamaria Naggi; Giangiacomo Torri; Benito Casu; Pasqua Oreste; Giorgio Zoppetti; Jin-Ping Li; Ulf Lindahl
Toward a biotechnological heparin through combined chemical and enzymatic modification of the Escherichia coli K5 polysaccharide.
Seminars in thrombosis and hemostasis 2001;27(5):437-43.
2000: Edwin A Yates; F Santini; B De Cristofano; N Payre; Cesare Cosentino; marco Guerrini; Annamaria Naggi; Giangiacomo Torri; Milos Hricovini
Effect of substitution pattern on 1H, 13C NMR chemical shifts and 1J(CH) coupling constants in heparin derivatives.
Carbohydrate research 2000;329(1):239-47.
2000: SF Chavante; Elizeu A Santos; Fernanda W Oliveira; marco Guerrini; Giangiacomo Torri; Benito Casu; Carl P Dietrich; Helena B Nader
A novel heparan sulphate with high degree of N-sulphation and high heparin cofactor-II activity from the brine shrimp Artemia franciscana.
International journal of biological macromolecules 2000;27(1):49-57.
1999: M Iacomini; Benito Casu; marco Guerrini; Annamaria Naggi; A Pirola; Giangiacomo Torri
"Linkage region" sequences of heparins and heparan sulfates: detection and quantification by nuclear magnetic resonance spectroscopy.
Analytical biochemistry 1999;274(1):50-8.
1999: Helena B Nader; E Y Kobayashi; SF Chavante; Ivarne L S Tersariol; RA Castro; Samuel K Shinjo; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Carl P Dietrich
New insights on the specificity of heparin and heparan sulfate lyases from Flavobacterium heparinum revealed by the use of synthetic derivatives of K5 polysaccharide from E. coli and 2-O-desulfated heparin.
Glycoconjugate journal 1999;16(6):265-70.
1999: Benito Casu; Giangiacomo Torri
Structural characterization of low molecular weight heparins.
Seminars in thrombosis and hemostasis 1999;25 Suppl 3():17-25.
1998: G Crini; Cesare Cosentino; S Bertini; Annamaria Naggi; Giangiacomo Torri; C Vecchi; Ludovic Janus; Michel Morcellet
Solid state NMR spectroscopy study of molecular motion in cyclomaltoheptaose (beta-cyclodextrin) crosslinked with epichlorohydrin.
Carbohydrate research 1998;308(1-2):37-45.
1997: Milos Hricovíni; marco Guerrini; Giangiacomo Torri; Benito Casu
Motional properties of E. coli polysaccharide K5 in aqueous solution analyzed by NMR relaxation measurements.
Carbohydrate research 1997;300(1):69-76.
1997: Reinhard Malsch; marco Guerrini; C Berti; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Job Harenberg
Synthesis and biological effects of N-alkylamine-labeled low-molecular-mass dermatan sulfate.
Seminars in thrombosis and hemostasis 1997;23(2):99-107.
1996: E A Yates; F Santini; marco Guerrini; Annamaria Naggi; Giangiacomo Torri; Benito Casu
1H and 13C NMR spectral assignments of the major sequences of twelve systematically modified heparin derivatives.
Carbohydrate research 1996;294():15-27.
1996: G Crini; Michel Morcellet; Giangiacomo Torri
HPLC of structural isomers with cyclodextrin-poly(vinylamine)-coated silica columns, Part I: Synthesis and characterization of cyclodextrin-bonded stationary phases by NMR solid state.
Journal of chromatographic science 1996;34(11):477-84.
1996: Benito Casu; marco Guerrini; Annamaria Naggi; Giangiacomo Torri; L De-Ambrosi; G Boveri; S Gonella; A Cedro; L Ferró; E Lanzarotti; M Paterno; M Attolini; M G Valle
Characterization of sulfation patterns of beef and pig mucosal heparins by nuclear magnetic resonance spectroscopy.
Arzneimittel-Forschung 1996;46(5):472-7.
1995: Milos Hricovíni; marco Guerrini; Giangiacomo Torri; S Piani; F Ungarelli
Conformational analysis of heparin epoxide in aqueous solution. An NMR relaxation study.
Carbohydrate research 1995;277(1):11-23.
1995: Benito Casu; marco Guerrini; Annamaria Naggi; Giangiacomo Torri; L De-Ambrosi; G Boveri; S Gonella; G Ronzoni
Differentiation of beef and pig mucosal heparins by NMR spectroscopy.
Thrombosis and haemostasis 1995;74(4):1205.
1995: Job Harenberg; G Löhr; Reinhard Malsch; marco Guerrini; Giangiacomo Torri; Benito Casu; DL Heene
Magnetic bead protamine-linked microtiter assay for detection of heparin using iodinated low-molecular-mass heparin-tyramine.
Thrombosis research 1995;79(2):207-16.
1995: M Hricovíni; Giangiacomo Torri
Dynamics in aqueous solutions of the pentasaccharide corresponding to the binding site of heparin for antithrombin III studied by NMR relaxation measurements.
Carbohydrate research 1995;268(2):159-75.
1995: W Jeske; O Iqbal; S Gonnela; G Boveri; Giangiacomo Torri; L De Ambrosi; J Fareed
Pharmacologic profile of a low-molecular-weight heparin depolymerized by gamma-irradiation.
Seminars in thrombosis and hemostasis 1995;21(2):201-11.
1994: Giuseppe Mascellani; Lino Liverani; A Prete; G Bergonzini; P Bianchini; Giangiacomo Torri; A Bisio; marco Guerrini; Benito Casu
Quantitation of dermatan sulfate active site for heparin cofactor II by 1H nuclear magnetic resonance spectroscopy.
Analytical biochemistry 1994;223(1):135-41.
1994: Benito Casu; G Grazioli; N Razi; marco Guerrini; Annamaria Naggi; Giangiacomo Torri; Pasqua Oreste; F Tursi; Giorgio Zoppetti; Ulf Lindahl
Heparin-like compounds prepared by chemical modification of capsular polysaccharide from E. coli K5.
Carbohydrate research 1994;263(2):271-84.
1994: Reinhard Malsch; marco Guerrini; Giangiacomo Torri; G Löhr; Benito Casu; Job Harenberg
Synthesis of a N'-alkylamine anticoagulant active low-molecular-mass heparin for radioactive and fluorescent labeling.
Analytical biochemistry 1994;217(2):255-64.
1994: M J Machado; Philip A J Gorin; Giangiacomo Torri; Marcello Iacomini
The occurrence of glycolipids in the lichen Ramalina celastri.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1994;27(2):523-6.
1994: Reinhard Malsch; Job Harenberg; marco Guerrini; Giangiacomo Torri; Benito Casu; DL Heene
Semisynthesis and analysis of lipophilically modified unfractionated and low molecular mass heparins.
Seminars in thrombosis and hemostasis 1994;20(2):182-92.
1994: Annamaria Naggi; Benito Casu; B Crippa; S Magnaghi; L Silvestro; Giangiacomo Torri
Preparation and characterization of deuterium-labeled glycosaminoglycans.
Seminars in thrombosis and hemostasis 1994;20(2):168-75.
1994: Giangiacomo Torri; A Bisio; Benito Casu; marco Guerrini; Annamaria Naggi; M C Barbosa; C Sciorati; L Silvestro
Nuclear magnetic resonance analysis of human urine: influence of intravenous and oral administration of glycosaminoglycans.
Seminars in thrombosis and hemostasis 1994;20(2):144-51.
1993: Giuseppe Mascellani; Lino Liverani; P Bianchini; Bruna Parma; Giangiacomo Torri; A Bisio; marco Guerrini; Benito Casu
Structure and contribution to the heparin cofactor II-mediated inhibition of thrombin of naturally oversulphated sequences of dermatan sulphate.
The Biochemical journal 1993;296 ( Pt 3)():639-48.
1993: R Da Col; L Silvestro; Annamaria Naggi; Giangiacomo Torri; C Baiocchi; D Moltrasio; A Cedro; Ilario Viano
Characterization of the chemical structure of sulphated glycosaminoglycans after enzymatic digestion. Application of liquid chromatography-mass spectrometry with an atmospheric pressure interface.
Journal of chromatography 1993;647(2):289-300.
1993: M Gigli; G Ghiselli; Giangiacomo Torri; A Naggi; V Rizzo
A comparative study of low-density lipoprotein interaction with glycosaminoglycans.
Biochimica et biophysica acta 1993;1167(2):211-7.
1992: M Gigli; A Consonni; G Ghiselli; V Rizzo; A Naggi; Giangiacomo Torri
Heparin binding to human plasma low-density lipoproteins: dependence on heparin sulfation degree and chain length.
Biochemistry 1992;31(26):5996-6003.
1992: L Silvestro; Ilario Viano; Annamaria Naggi; Giangiacomo Torri; R Da Col; C Baiocchi
High-performance liquid chromatographic-mass spectrometric analysis of oligosaccharides from enzymatic digestion of glycosaminoglycans. Application to human samples.
Journal of chromatography 1992;591(1-2):225-32.
1991: Giangiacomo Torri
Electrophoretic and nuclear magnetic resonance characterization of non-heparin glycosaminoglycans.
Seminars in thrombosis and hemostasis 1991;17 Suppl 1():23-8.
1991: Rodolfo Pescador; Roberto Porta; M Mantovani; G Prino; Benito Casu; Annamaria Naggi; Giangiacomo Torri; J M Walenga; D A Hoppensteadt; J Fareed
Pharmacologic profile of sulfamino-galactosaminoglycans.
Seminars in thrombosis and hemostasis 1991;17 Suppl 1():74-9.
1990: M Kusche; Giangiacomo Torri; B Casu; Ulf Lindahl
Biosynthesis of heparin. Availability of glucosaminyl 3-O-sulfation sites.
The Journal of biological chemistry 1990;265(13):7292-300.
1990: D R Ferro; A Provasoli; M Ragazzi; Benito Casu; Giangiacomo Torri; V Bossennec; B Perly; Pierre Sinaÿ; Maurice Petitou; J Choay
Conformer populations of L-iduronic acid residues in glycosaminoglycan sequences.
Carbohydrate research 1990;195(2):157-67.
1988: Helena B Nader; T M Ferreira; L Toma; SF Chavante; Carl P Dietrich; Benito Casu; Giangiacomo Torri
Maintenance of heparan sulfate structure throughout evolution: chemical and enzymic degradation, and 13C-n.m.r.-spectral evidence.
Carbohydrate research 1988;184():292-300.
1987: Maurice Petitou; Philippe Duchaussoy; I Lederman; J Choay; Jean-Claude Jacquinet; Pierre Sinaÿ; Giangiacomo Torri
Synthesis of heparin fragments: a methyl alpha-pentaoside with high affinity for antithrombin III.
Carbohydrate research 1987;167():67-75.
1987: M Ragazzi; D R Ferro; B Perly; Giangiacomo Torri; Benito Casu; Pierre Sinaÿ; Maurice Petitou; J Choay
Conformation of the pentasaccharide corresponding to the binding site of heparin to antithrombin-III.
Carbohydrate research 1987;165(1):c1-5.
1987: Annamaria Naggi; Giangiacomo Torri; Benito Casu; J Pangrazzi; M Abbadini; M Zametta; Maria Benedetta Donati; J Lansen; J P Maffrand
"Supersulfated" heparin fragments, a new type of low-molecular weight heparin. Physico-chemical and pharmacological properties.
Biochemical pharmacology 1987;36(12):1895-900.
1987: Benito Casu; Annamaria Naggi; Pasqua Oreste; Giangiacomo Torri; J Pangrazzj; A Maggi; M Abbadini; Maria Benedetta Donati
Bleeding associated with heparin contaminants.
Lancet 1987;1(8541):1088.
1986: Benito Casu; J Choay; D R Ferro; G Gatti; Jean-Claude Jacquinet; Maurice Petitou; A Provasoli; M Ragazzi; P Sinay; Giangiacomo Torri
Controversial glycosaminoglycan conformations.
Nature 1986;322(6076):215-6.
1986: Benito Casu; Giuseppe Diamantini; G Fedeli; M Mantovani; Pasqua Oreste; Rodolfo Pescador; Roberto Porta; G Prino; Giangiacomo Torri; Giorgio Zoppetti
Retention of antilipemic activity by periodate-oxidized non-anticoagulant heparins.
Arzneimittel-Forschung 1986;36(4):637-42.
1986: Maurice Petitou; Philippe Duchaussoy; I Lederman; J Choay; Pierre Sinaÿ; Jean-Claude Jacquinet; Giangiacomo Torri
Synthesis of heparin fragments. A chemical synthesis of the pentasaccharide O-(2-deoxy-2-sulfamido-6-O-sulfo-alpha-D-glucopyranosyl)-(1-4 )-O-(beta-D-glucopyranosyluronic acid)-(1-4)-O-(2-deoxy-2-sulfamido-3,6-di-O-sulfo-alpha-D-glu copyranosyl)-(1-4)-O-(2-O-sulfo-alpha-L-idopyranosyluronic acid)-(1-4)-2-deoxy-2-sulfamido-6-O-sulfo-D-glucopyranose decasodium salt, a heparin fragment having high affinity for antithrombin III.
Carbohydrate research 1986;147(2):221-36.
1985: J Pangrazzi; M Abbadini; M Zametta; Annamaria Naggi; Giangiacomo Torri; Benito Casu; Maria Benedetta Donati
Antithrombotic and bleeding effects of a low molecular weight heparin fraction.
Biochemical pharmacology 1985;34(18):3305-8.
1985: M Porro; paolo costantino; S Viti; F Vannozzi; A Naggi; Giangiacomo Torri
Specific antibodies to diphtheria toxin and type 6A pneumococcal capsular polysaccharide induced by a model of semi-synthetic glycoconjugate antigen.
Molecular immunology 1985;22(8):907-19.
1985: Giangiacomo Torri; Benito Casu; G Gatti; Maurice Petitou; J Choay; Jean-Claude Jacquinet; Pierre Sinaÿ
Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: evidence for conformational peculiarity of the sulfated iduronate residue.
Biochemical and biophysical research communications 1985;128(1):134-40.
1985: P Bianchini; B Osima; Bruna Parma; Helena B Nader; Carl P Dietrich; Benito Casu; Giangiacomo Torri
Fractionation and structural features of two heparin families with high antithrombotic, antilipemic and anticoagulant activities.
Arzneimittel-Forschung 1985;35(8):1215-9.
1983: Benito Casu; E A Johnson; M Mantovani; B Mulloy; Pasqua Oreste; Rodolfo Pescador; G Prino; Giangiacomo Torri; Giorgio Zoppetti
Correlation between structure, fat-clearing and anticoagulant properties of heparins and heparan sulphates.
Arzneimittel-Forschung 1983;33(1):135-42.
1981: Benito Casu; Pasqua Oreste; Giangiacomo Torri; Giorgio Zoppetti; J Choay; JC Lormeau; Maurice Petitou; P Sinäy
The structure of heparin oligosaccharide fragments with high anti-(factor Xa) activity containing the minimal antithrombin III-binding sequence. Chemical and 13C nuclear-magnetic-resonance studies.
The Biochemical journal 1981;197(3):599-609.
1980: J Choay; JC Lormeau; Maurice Petitou; P Sinay; Benito Casu; Pasqua Oreste; Giangiacomo Torri; G Gatti
Anti-Xa active heparin oligosaccharides.
Thrombosis research 1980;18(3-4):573-8.
1980: Benito Casu; M Moretti; Pasqua Oreste; A Riva; Giangiacomo Torri; J R Vercellotti
Glycosaminoglycans from pig duodenum.
Arzneimittel-Forschung 1980;30(11):1889-92.
1979: B Casu; Giangiacomo Torri; J R Vercellotti
Fractionation and characterization of glycosaminoglycans of mammalian origin.
Pharmacological research communications 1979;11(4):297-310.
1979: E Cofrancesco; F Radaelli; E Pogliani; N Amici; Giangiacomo Torri; B Casu
Correlation of sulfate content and degree of carboxylation of heparin and related glycosaminoglycans with anticomplement activity. Relationships to the anticoagulant and platelet-aggregating activities.
Thrombosis research 1979;14(1):179-87.