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Michael Bacher

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TOP 3
Yvonne Roettger; Inga Zerr; Michael Bacher; Richard Dodel; Yansheng Du; Jan-Philipp Bach
Immunotherapy in prion disease.
D Mengel; Frauke Neff; W H Oertel; S Röskam; J P Bach; Michael Bacher; K Balakrishnan; O Deuster; M Gold; Richard Dodel
Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment.
Amalia M Dolga; Nunzianna Doti; Maike Gold; Till Letsche; Michael Bacher; Nipavan Chiamvimonvat; Richard Dodel; Carsten Culmsee
Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia.

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All Publications

2013: Yvonne Roettger; Inga Zerr; Michael Bacher; Richard Dodel; Yansheng Du; Jan-Philipp Bach
Immunotherapy in prion disease.
Nature reviews. Neurology 2013;9(2):98-105.
2013: D Mengel; Frauke Neff; W H Oertel; S Röskam; J P Bach; Michael Bacher; K Balakrishnan; O Deuster; M Gold; Richard Dodel
Naturally occurring autoantibodies interfere with β-amyloid metabolism and improve cognition in a transgenic mouse model of Alzheimer's disease 24 h after single treatment.
Translational psychiatry 2013;3():e236.
2012: Amalia M Dolga; Nunzianna Doti; Maike Gold; Till Letsche; Michael Bacher; Nipavan Chiamvimonvat; Richard Dodel; Carsten Culmsee
Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia.
Glia 2012;60(12):2050-64.
2011: Nina Baron; Oliver Deuster; Carmen Noelker; Carsten Stüer; Herwig Strik; Carlo Schaller; Richard Dodel; Bernhard Meyer; Michael Bacher
Role of macrophage migration inhibitory factor in primary glioblastoma multiforme cells.
Journal of neuroscience research 2011;89(5):711-7.
2011: Richard Dodel; Karthikeyan Balakrishnan; Kathy Keyvani; Oliver Deuster; Frauke Neff; Luminita-Cornelia Andrei-Selmer; Stephan Röskam; Carsten Stüer; Yousef Al-Abed; Carmen Noelker; Monika Balzer-Geldsetzer; Wolfgang Oertel; Yansheng Du; Michael Bacher
Naturally occurring autoantibodies against beta-amyloid: investigating their role in transgenic animal and in vitro models of Alzheimer's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(15):5847-54.
2011: Jan-Philipp Bach; Yousef Al-Abed; Monika Balzer-Geldsetzer; Richard Dodel; Andreas Kautz; David Mengel; Tina Wahle; Michael Bacher
The role of CNI-1493 in the function of primary microglia with respect to amyloid-β.
Journal of Alzheimer's disease : JAD 2011;26(1):69-80.
2010: Sascha Hagemann; Alexander Faude; Monika Rabenstein; Monika Balzer-Geldsetzer; Carmen Nölker; Michael Bacher; Richard Dodel
Reducing sample complexity of polyclonal human autoantibodies by chromatofocusing.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2010;878(24):2249-54.
2010: Jan-Philipp Bach; Neeraj Kumar; Candan Depboylu; Carmen Noelker; Thomas Klockgether; Michael Bacher; Monika Balzer-Geldsetzer; Richard Dodel
Copper deficiency associated with severe neurological disorder--a genetic work-up of possible mutations in copper transport proteins.
Journal of the neurological sciences 2010;291(1-2):95-7.
2010: Dirk Bartnik; Susanne Aileen Funke; Luminita-Cornelia Andrei-Selmer; Michael Bacher; Richard Dodel; Dieter Willbold
Differently selected D-enantiomeric peptides act on different Abeta species.
Rejuvenation research 2010;13(2-3):202-5.
2010: Richard Dodel; Frauke Neff; Carmen Noelker; Refik Pul; Yansheng Du; Michael Bacher; Wolfgang Oertel
Intravenous immunoglobulins as a treatment for Alzheimer's disease: rationale and current evidence.
Drugs 2010;70(5):513-28.
2010: Michael Bacher; Oliver Deuster; Bayan Aljabari; Rupert Egensperger; Frauke Neff; Frank Jessen; Julius Popp; Carmen Noelker; Jens Peter Reese; Yousef Al-Abed; Richard Dodel
The role of macrophage migration inhibitory factor in Alzheimer's disease.
Molecular medicine (Cambridge, Mass.) 2010;16(3-4):116-21.
2010: Stephan Röskam; Frauke Neff; Rainer Schwarting; Michael Bacher; Richard Dodel
APP transgenic mice: the effect of active and passive immunotherapy in cognitive tasks.
Neuroscience and biobehavioral reviews 2010;34(4):487-99.
2010: Karthikeyan Balakrishnan; Luminita-Cornelia Andrei-Selmer; Thorsten Selmer; Michael Bacher; Richard Dodel
Comparison of intravenous immunoglobulins for naturally occurring autoantibodies against amyloid-beta.
Journal of Alzheimer's disease : JAD 2010;20(1):135-43.
2009: Jan-Philipp Bach; Oliver Deuster; Monika Balzer-Geldsetzer; Bernhard Meyer; Richard Dodel; Michael Bacher
The role of macrophage inhibitory factor in tumorigenesis and central nervous system tumors.
Cancer 2009;115(10):2031-40.
2009: Jörg Schrader; Oliver Deuster; Birgit Rinn; Martina Schulz; Andreas Kautz; Richard Dodel; Bernhard Meyer; Yousef Al-Abed; Karthikeyan Balakrishnan; Jens P Reese; Michael Bacher
Restoration of contact inhibition in human glioblastoma cell lines after MIF knockdown.
BMC cancer 2009;9():464.
2008: Michael Bacher; Richard Dodel; Bayan Aljabari; Kathy Keyvani; Philippe Marambaud; Rakez Kayed; Charles G Glabe; Nicole Goertz; Anne Hoppmann; Norbert Sachser; Jens Klotsche; Susanne Schnell; Lars Lewejohann; Yousef Al-Abed
CNI-1493 inhibits Abeta production, plaque formation, and cognitive deterioration in an animal model of Alzheimer's disease.
The Journal of experimental medicine 2008;205(7):1593-9.
2008: Frauke Neff; Xing Wei; Carmen Nölker; Michael Bacher; Yansheng Du; Richard Dodel
Immunotherapy and naturally occurring autoantibodies in neurodegenerative disorders.
Autoimmunity reviews 2008;7(6):501-7.
2008: Jan-Philipp Bach; Birgit Rinn; Bernhard Meyer; Richard Dodel; Michael Bacher
Role of MIF in inflammation and tumorigenesis.
Oncology 2008;75(3-4):127-33.
2005: Yousef Al-Abed; Darrin R Dabideen; Bayan Aljabari; Aline Valster; Davorka Messmer; Mahendar Ochani; Mahira Tanovic; Kanta Ochani; Michael Bacher; Ferdinando Nicoletti; Christine Metz; Valentin A Pavlov; Edmund Miller; Kevin Tracey
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis.
The Journal of biological chemistry 2005;280(44):36541-4.
2005: Yi Ren; Simon Law; Xin Huang; Ping-Yin Lee; Michael Bacher; Gopesh Srivastava; John Wong
Macrophage migration inhibitory factor stimulates angiogenic factor expression and correlates with differentiation and lymph node status in patients with esophageal squamous cell carcinoma.
Annals of surgery 2005;242(1):55-63.
2005: Ivana Cvetkovic; Yousef Al-Abed; Djordje Miljkovic; Danijela Maksimovic-Ivanic; Jesse Roth; Michael Bacher; Hui Y Lan; Ferdinando Nicoletti; Stanislava Stosic-Grujicic
Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes.
Endocrinology 2005;146(7):2942-51.
2004: Yi Ren; Hiu Man Chan; Zhi Li; Chenlung Lin; John Nicholls; Chi Fong Chen; Ping-Yin Lee; Vincent Lui; Michael Bacher; Paul K H Tam
Upregulation of macrophage migration inhibitory factor contributes to induced N-Myc expression by the activation of ERK signaling pathway and increased expression of interleukin-8 and VEGF in neuroblastoma.
Oncogene 2004;23(23):4146-54.
2003: Yi Ren; Hong-Teng Tsui; Ronnie T P Poon; Irene Oi-Lin Ng; Zhi Li; Yongxiong Chen; Guoping Jiang; Cecilia Lau; Wan Ching Yu; Michael Bacher; Sheung-Tat Fan
Macrophage migration inhibitory factor: roles in regulating tumor cell migration and expression of angiogenic factors in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2003;107(1):22-9.
2003: Jörg Bojunga; Klaus Kusterer; Michael Bacher; Ralf Kurek; Klaus-H Usadel; Heiner Renneberg
Macrophage migration inhibitory factor and development of type-1 diabetes in non-obese diabetic mice.
Cytokine 2003;21(4):179-86.
2003: Michael Bacher; Jörg Schrader; Nancy Thompson; Karen Kuschela; Diethard Gemsa; Gerard Waeber; Jürgen Schlegel
Up-regulation of macrophage migration inhibitory factor gene and protein expression in glial tumor cells during hypoxic and hypoglycemic stress indicates a critical role for angiogenesis in glioblastoma multiforme.
The American journal of pathology 2003;162(1):11-7.
2002: Reiner Mengel; Michael Bacher; Lavin Flores-de-Jacoby
Interactions between stress, interleukin-1beta, interleukin-6 and cortisol in periodontally diseased patients.
Journal of clinical periodontology 2002;29(11):1012-22.
2002: Ute Arndt; Gunther Wennemuth; Peter Barth; Marianne Nain; Yousef Al-Abed; Andreas Meinhardt; Diethard Gemsa; Michael Bacher
Release of macrophage migration inhibitory factor and CXCL8/interleukin-8 from lung epithelial cells rendered necrotic by influenza A virus infection.
Journal of virology 2002;76(18):9298-306.
2002: Michael Bacher; Markus Eickmann; Joerg Schrader; Diethard Gemsa; Andreas Heiske
Human cytomegalovirus-mediated induction of MIF in fibroblasts.
Virology 2002;299(1):32-7.
2002: Michael Bacher; Eberhard Weihe; Bernhard Dietzschold; Andreas Meinhardt; Helmut Vedder; Diethard Gemsa; Michael Bette
Borna disease virus-induced accumulation of macrophage migration inhibitory factor in rat brain astrocytes is associated with inhibition of macrophage infiltration.
Glia 2002;37(4):291-306.
2001: Regina Eickhoff; Beate Wilhelm; Heiner Renneberg; Gunther Wennemuth; Michael Bacher; Dietmar Linder; R Bucala; Jürgen Seitz; Andreas Meinhardt
Purification and characterization of macrophage migration inhibitory factor as a secretory protein from rat epididymis: evidences for alternative release and transfer to spermatozoa.
Molecular medicine (Cambridge, Mass.) 2001;7(1):27-35.
2000: Helmut Vedder; Jürgen-Christian Krieg; B Gerlach; Diethard Gemsa; Michael Bacher
Expression and glucocorticoid regulation of macrophage migration inhibitory factor (MIF) in hippocampal and neocortical rat brain cells in culture.
Brain research 2000;869(1-2):25-30.
2000: Gunther Wennemuth; Gerhard Aumüller; Michael Bacher; Andreas Meinhardt
Macrophage migration inhibitory factor-induced Ca(2+) response in rat testicular peritubular cells.
Biology of reproduction 2000;62(6):1632-9.
2000: Andreas Meinhardt; Michael Bacher; Gunther Wennemuth; Regina Eickhoff; Mark P Hedger
Macrophage migration inhibitory factor (MIF) as a paracrine mediator in the interaction of testicular somatic cells.
Andrologia 2000;32(1):46-8.
1999: Martin Steinhoff; Andreas Meinhardt; A Steinhoff; Diethard Gemsa; R Bucala; Michael Bacher
Evidence for a role of macrophage migration inhibitory factor in psoriatic skin disease.
The British journal of dermatology 1999;141(6):1061-6.
1999: Andreas Meinhardt; Michael Bacher; Moira K O'Bryan; James R McFarlane; C Mallidis; C Lehmann; Christine N Metz; David M de Kretser; R Bucala; Mark P Hedger
A switch in the cellular localization of macrophage migration inhibitory factor in the rat testis after ethane dimethane sulfonate treatment.
Journal of cell science 1999;112 ( Pt 9)():1337-44.
1999: Jason Chesney; R Mitchell; Fabio Benigni; Michael Bacher; L Spiegel; Yousef Al-Abed; J H Han; Christine Metz; Richard Bucala
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):3047-52.
1999: Jason Chesney; Christine Metz; Michael Bacher; T Peng; A Meinhardt; Richard Bucala
An essential role for macrophage migration inhibitory factor (MIF) in angiogenesis and the growth of a murine lymphoma.
Molecular medicine (Cambridge, Mass.) 1999;5(3):181-91.
1998: HY Lan; N Yang; Fiona G Brown; Nicole M Isbel; David J Nikolic-Paterson; Wei Mu; Christine N Metz; Michael Bacher; Robert C Atkins; Richard Bucala
Macrophage migration inhibitory factor expression in human renal allograft rejection.
Transplantation 1998;66(11):1465-71.
1998: Andreas Meinhardt; Michael Bacher; Christine Metz; R Bucala; Nigel G Wreford; H Lan; R Atkins; Mark P Hedger
Local regulation of macrophage subsets in the adult rat testis: examination of the roles of the seminiferous tubules, testosterone, and macrophage-migration inhibitory factor.
Biology of reproduction 1998;59(2):371-8.
1998: Michael Bacher; Andreas Meinhardt; H Y Lan; Firdaus S Dhabhar; W Mu; Christine N Metz; Jason Chesney; Diethard Gemsa; T Donnelly; R C Atkins; Richard Bucala
MIF expression in the rat brain: implications for neuronal function.
Molecular medicine (Cambridge, Mass.) 1998;4(4):217-30.
1998: Gregory H Tesch; David J Nikolic-Paterson; Christine N Metz; Wei Mu; Michael Bacher; Richard Bucala; Robert C Atkins; HY Lan
Rat mesangial cells express macrophage migration inhibitory factor in vitro and in vivo.
Journal of the American Society of Nephrology : JASN 1998;9(3):417-24.
1998: Jason Chesney; Christine Metz; Abram B Stavitsky; Michael Bacher; Richard Bucala
Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):419-25.
1997: D Bussfeld; Michael Bacher; A Moritz; Diethard Gemsa; Hans Sprenger
Expression of transcription factor genes after influenza A virus infection.
Immunobiology 1997;198(1-3):291-8.
1997: Jason Chesney; Michael Bacher; A Bender; Richard Bucala
The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6307-12.
1997: K Miyazaki; Nicole M Isbel; HY Lan; M Hattori; K Ito; Michael Bacher; Richard Bucala; Robert C Atkins; David J Nikolic-Paterson
Up-regulation of macrophage colony-stimulating factor (M-CSF) and migration inhibitory factor (MIF) expression and monocyte recruitment during lipid-induced glomerular injury in the exogenous hypercholesterolaemic (ExHC) rat.
Clinical and experimental immunology 1997;108(2):318-23.
1997: Gérard Waeber; Thierry Calandra; Raphael Roduit; Jacques-Antoine Haefliger; Christophe Bonny; Norman W Thompson; Bernard Thorens; E Temler; A Meinhardt; Michael Bacher; Christine N Metz; Pascal Nicod; R Bucala
Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4782-7.
1997: HY Lan; Michael Bacher; N Yang; Wei Mu; David J Nikolic-Paterson; Christine Metz; A Meinhardt; Richard Bucala; Robert C Atkins
The pathogenic role of macrophage migration inhibitory factor in immunologically induced kidney disease in the rat.
The Journal of experimental medicine 1997;185(8):1455-65.
1997: HY Lan; N Yang; Christine Metz; Wei Mu; Q Song; David J Nikolic-Paterson; Michael Bacher; Richard Bucala; Robert C Atkins
TNF-alpha up-regulates renal MIF expression in rat crescentic glomerulonephritis.
Molecular medicine (Cambridge, Mass.) 1997;3(2):136-44.
1997: Michael Bacher; Andreas Meinhardt; H Y Lan; W Mu; Christine N Metz; Jason Chesney; Thierry Calandra; Diethard Gemsa; T Donnelly; R C Atkins; Richard Bucala
Migration inhibitory factor expression in experimentally induced endotoxemia.
The American journal of pathology 1997;150(1):235-46.
1996: Andreas Meinhardt; Michael Bacher; James R McFarlane; Christine N Metz; Jürgen Seitz; Mark P Hedger; David M de Kretser; Richard Bucala
Macrophage migration inhibitory factor production by Leydig cells: evidence for a role in the regulation of testicular function.
Endocrinology 1996;137(11):5090-5.
1996: HY Lan; Wei Mu; N Yang; Andreas Meinhardt; David J Nikolic-Paterson; YY Ng; Michael Bacher; Robert C Atkins; Richard Bucala
De Novo renal expression of macrophage migration inhibitory factor during the development of rat crescentic glomerulonephritis.
The American journal of pathology 1996;149(4):1119-27.
1996: Michael Bacher; Christine N Metz; T Calandra; K Mayer; Jason Chesney; M Lohoff; Diethard Gemsa; T Donnelly; Richard Bucala
An essential regulatory role for macrophage migration inhibitory factor in T-cell activation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(15):7849-54.
1996: C Lehmann; Hans Sprenger; M Nain; Michael Bacher; Diethard Gemsa
Infection of macrophages by influenza A virus: characteristics of tumour necrosis factor-alpha (TNF alpha) gene expression.
Research in virology 1996;147(2-3):123-30.
1996: Jürgen Bernhagen; Michael Bacher; T Calandra; Christine N Metz; S B Doty; T Donnelly; Richard Bucala
An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction.
The Journal of experimental medicine 1996;183(1):277-82.
1995: T Calandra; Jürgen Bernhagen; Christine N Metz; L A Spiegel; Michael Bacher; T Donnelly; Anthony Cerami; Richard Bucala
MIF as a glucocorticoid-induced modulator of cytokine production.
Nature 1995;377(6544):68-71.
1995: R Mitchell; Michael Bacher; Jürgen Bernhagen; T Pushkarskaya; Michael F Seldin; Richard Bucala
Cloning and characterization of the gene for mouse macrophage migration inhibitory factor (MIF).
Journal of immunology (Baltimore, Md. : 1950) 1995;154(8):3863-70.
1995: Andreas Meinhardt; M Parvinen; Michael Bacher; Gerhard Aumüller; H Hakovirta; A Yagi; Jürgen Seitz
Expression of mitochondrial heat shock protein 60 in distinct cell types and defined stages of rat seminiferous epithelium.
Biology of reproduction 1995;52(4):798-807.
1994: H Fesq; Michael Bacher; M Nain; Diethard Gemsa
Programmed cell death (apoptosis) in human monocytes infected by influenza A virus.
Immunobiology 1994;190(1-2):175-82.
1994: Hans Sprenger; Michael Bacher; E Rischkowsky; A Bender; M Nain; Diethard Gemsa
Characterization of a high molecular weight tumor necrosis factor-alpha mRNA in influenza A virus-infected macrophages.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):280-9.
1993: Michael Bacher; U Rausch; H W Goebel; Bernhard Polzar; Hans Georg Mannherz; Gerhard Aumüller
Stromal and epithelial cells from rat ventral prostate during androgen deprivation and estrogen treatment--regulation of transcription.
Experimental and clinical endocrinology 1993;101(2):78-86.
1993: G Q Zhao; Michael Bacher; B Friedrichs; W Schmidt; U Rausch; H W Goebel; P Tuohimaa; Gerhard Aumüller
Functional properties of isolated stroma and epithelium from rat ventral prostate during androgen deprivation and estrogen treatment.
Experimental and clinical endocrinology 1993;101(2):69-77.
1993: Gerhard Aumüller; H W Goebel; Michael Bacher; Wolfgang Eicheler; U Rausch
[Current aspects on morphology and functions of the prostate].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1993;77():1-18.
1992: H W Goebel; U Rausch; Martin Steinhoff; Jürgen Seitz; Michael Bacher; M Papotti; G Bussolati; P Tuohimaa; Gerhard Aumüller
Arguments against the prostatic origin of the R-3327 Dunning H tumor.
Virchows Archiv. B, Cell pathology including molecular pathology 1992;62(1):9-18.