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SUSAN COLE

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TOP 3
Kazuma Maeno; Akio Nakajima; Gwenaëlle Conseil; Alice Rothnie; Roger G Deeley; SUSAN COLE
Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
Gwenaëlle Conseil; Alice J Rothnie; Roger G Deeley; SUSAN COLE
Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Md Tozammel Hoque; Gwenaëlle Conseil; SUSAN COLE
Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells.

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2009: Kazuma Maeno; Akio Nakajima; Gwenaëlle Conseil; Alice Rothnie; Roger G Deeley; SUSAN COLE
Molecular basis for reduced estrone sulfate transport and altered modulator sensitivity of transmembrane helix (TM) 6 and TM17 mutants of multidrug resistance protein 1 (ABCC1).
Drug metabolism and disposition: the biological fate of chemicals 2009;37(7):1411-20.
2009: Gwenaëlle Conseil; Alice J Rothnie; Roger G Deeley; SUSAN COLE
Multiple roles of charged amino acids in cytoplasmic loop 7 for expression and function of the multidrug and organic anion transporter MRP1 (ABCC1).
Molecular pharmacology 2009;75(2):397-406.
2009: Md Tozammel Hoque; Gwenaëlle Conseil; SUSAN COLE
Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells.
Biochemical and biophysical research communications 2009;379(1):60-4.
2008: Lei Qin; Jimin Zheng; Caroline E Grant; Zongchao Jia; SUSAN COLE; Roger G Deeley
Residues responsible for the asymmetric function of the nucleotide binding domains of multidrug resistance protein 1.
Biochemistry 2008;47(52):13952-65.
2008: Caroline E Grant; Mian Gao; Marianne K DeGorter; SUSAN COLE; Roger G Deeley
Structural determinants of substrate specificity differences between human multidrug resistance protein (MRP) 1 (ABCC1) and MRP3 (ABCC3).
Drug metabolism and disposition: the biological fate of chemicals 2008;36(12):2571-81.
2008: Alice Rothnie; Gwenaëlle Conseil; Andrea Y T Lau; Roger G Deeley; SUSAN COLE
Mechanistic differences between GSH transport by multidrug resistance protein 1 (MRP1/ABCC1) and GSH modulation of MRP1-mediated transport.
Molecular pharmacology 2008;74(6):1630-40.
2008: Paul E Bandler; Christopher J Westlake; Caroline E Grant; SUSAN COLE; Roger G Deeley
Identification of regions required for apical membrane localization of human multidrug resistance protein 2.
Molecular pharmacology 2008;74(1):9-19.
2008: Md Tozammel Hoque; SUSAN COLE
Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.
Cancer research 2008;68(12):4802-9.
2008: Isabelle J Létourneau; Akio Nakajima; Roger G Deeley; SUSAN COLE
Role of proline 1150 in functional interactions between the membrane spanning domains and nucleotide binding domains of the MRP1 (ABCC1) transporter.
Biochemical pharmacology 2008;75(8):1659-69.
2008: Andrew J Slot; Dana D Wise; Roger G Deeley; Terrence J Monks; SUSAN COLE
Modulation of human multidrug resistance protein (MRP) 1 (ABCC1) and MRP2 (ABCC2) transport activities by endogenous and exogenous glutathione-conjugated catechol metabolites.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(3):552-60.
2008: Marianne K DeGorter; Gwenaëlle Conseil; Roger G Deeley; Robert L Campbell; SUSAN COLE
Molecular modeling of the human multidrug resistance protein 1 (MRP1/ABCC1).
Biochemical and biophysical research communications 2008;365(1):29-34.
2007: Isabelle J Létourneau; Andrew J Slot; Roger G Deeley; SUSAN COLE
Mutational analysis of a highly conserved proline residue in MRP1, MRP2, and MRP3 reveals a partially conserved function.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(8):1372-9.
2007: Shelagh E L Mirski; Kathryn E Sparks; Beate Friedrich; Matthias Köhler; Yin-Yuan Mo; William T Beck; SUSAN COLE
Topoisomerase II binds importin alpha isoforms and exportin/CRM1 but does not shuttle between the nucleus and cytoplasm in proliferating cells.
Experimental cell research 2007;313(3):627-37.
2007: Jessica P Wyles; Zhongqin Wu; Shelagh E L Mirski; SUSAN COLE
Nuclear interactions of topoisomerase II alpha and beta with phospholipid scramblase 1.
Nucleic acids research 2007;35(12):4076-85.
2006: SUSAN COLE; Roger G Deeley
Transport of glutathione and glutathione conjugates by MRP1.
Trends in pharmacological sciences 2006;27(8):438-46.
2006: Roger G Deeley; Christopher J Westlake; SUSAN COLE
Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.
Physiological reviews 2006;86(3):849-99.
2006: Alice Rothnie; Richard Callaghan; Roger G Deeley; SUSAN COLE
Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1).
The Journal of biological chemistry 2006;281(20):13906-14.
2006: Da-Wei Zhang; Kenichi Nunoya; Monika Vasa; Hong-Mei Gu; SUSAN COLE; Roger G Deeley
Mutational analysis of polar amino acid residues within predicted transmembrane helices 10 and 16 of multidrug resistance protein 1 (ABCC1): effect on substrate specificity.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(4):539-46.
2006: Roger G Deeley; SUSAN COLE
Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).
FEBS letters 2006;580(4):1103-11.
2006: Gwenaëlle Conseil; Roger G Deeley; SUSAN COLE
Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
The Journal of biological chemistry 2006;281(1):43-50.
2006: Joslynn G Affleck; Khalid M Al-Batayneh; Katerina Neumann; SUSAN COLE; Virginia K Walker
Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
European journal of pharmacology 2006;529(1-3):71-8.
2005: Peng Wu; Curtis J Oleschuk; Qingcheng Mao; Bernd Keller; Roger G Deeley; SUSAN COLE
Analysis of human multidrug resistance protein 1 (ABCC1) by matrix-assisted laser desorption ionization/time of flight mass spectrometry: toward identification of leukotriene C4 binding sites.
Molecular pharmacology 2005;68(5):1455-65.
2005: Isabelle J Létourneau; Roger G Deeley; SUSAN COLE
Functional characterization of non-synonymous single nucleotide polymorphisms in the gene encoding human multidrug resistance protein 1 (MRP1/ABCC1).
Pharmacogenetics and genomics 2005;15(9):647-57.
2005: Gwenaëlle Conseil; Roger G Deeley; SUSAN COLE
Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.
Pharmacogenetics and genomics 2005;15(8):523-33.
2005: Lea Payen; Mian Gao; Christopher J Westlake; Ashley Theis; SUSAN COLE; Roger G Deeley
Functional interactions between nucleotide binding domains and leukotriene C4 binding sites of multidrug resistance protein 1 (ABCC1).
Molecular pharmacology 2005;67(6):1944-53.
2005: Isabelle J Létourneau; Raymond J Bowers; Roger G Deeley; SUSAN COLE
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites.
Toxicology letters 2005;157(1):9-19.
2005: Elaine M Leslie; Roger G Deeley; SUSAN COLE
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense.
Toxicology and applied pharmacology 2005;204(3):216-37.
2005: Christopher J Westlake; SUSAN COLE; Roger G Deeley
Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking.
Molecular biology of the cell 2005;16(5):2483-92.
2005: Gwenaëlle Conseil; Roger G Deeley; SUSAN COLE
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.
Biochemical pharmacology 2005;69(3):451-61.
2004: Christopher J Westlake; Lea Payen; Mian Gao; SUSAN COLE; Roger G Deeley
Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
The Journal of biological chemistry 2004;279(51):53571-83.
2004: Donna Situ; Anass Haimeur; Gwenaëlle Conseil; Kathryn E Sparks; Dawei Zhang; Roger G Deeley; SUSAN COLE
Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transporter.
The Journal of biological chemistry 2004;279(37):38871-80.
2004: Qingcheng Mao; Gwenaëlle Conseil; Anshul Gupta; SUSAN COLE; Jashvant D Unadkat
Functional expression of the human breast cancer resistance protein in Pichia pastoris.
Biochemical and biophysical research communications 2004;320(3):730-7.
2004: Da-Wei Zhang; Kenichi Nunoya; Monika Vasa; Hong-Mei Gu; Ashley Theis; SUSAN COLE; Roger G Deeley
Transmembrane helix 11 of multidrug resistance protein 1 (MRP1/ABCC1): identification of polar amino acids important for substrate specificity and binding of ATP at nucleotide binding domain 1.
Biochemistry 2004;43(29):9413-25.
2004: Anass Haimeur; Gwenaëlle Conseil; Roger G Deeley; SUSAN COLE
Mutations of charged amino acids in or near the transmembrane helices of the second membrane spanning domain differentially affect the substrate specificity and transport activity of the multidrug resistance protein MRP1 (ABCC1).
Molecular pharmacology 2004;65(6):1375-85.
2004: Koji Koike; Gwenaëlle Conseil; Elaine M Leslie; Roger G Deeley; SUSAN COLE
Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.
The Journal of biological chemistry 2004;279(13):12325-36.
2004: Koji Koike; Roger G Deeley; SUSAN COLE
Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1).
Biochemical and biophysical research communications 2004;315(3):719-25.
2004: Anass Haimeur; Gwenaëlle Conseil; Roger G Deeley; SUSAN COLE
The MRP-related and BCRP/ABCG2 multidrug resistance proteins: biology, substrate specificity and regulation.
Current drug metabolism 2004;5(1):21-53.
2004: Jeff D Campbell; Koji Koike; Christophe Moreau; Michael S P Sansom; Roger G Deeley; SUSAN COLE
Molecular modeling correctly predicts the functional importance of Phe594 in transmembrane helix 11 of the multidrug resistance protein, MRP1 (ABCC1).
The Journal of biological chemistry 2004;279(1):463-8.
2003: Christopher J Westlake; Yue-Ming Qian; Mian Gao; Monika Vasa; SUSAN COLE; Roger G Deeley
Identification of the structural and functional boundaries of the multidrug resistance protein 1 cytoplasmic loop 3.
Biochemistry 2003;42(48):14099-113.
2003: Da-Wei Zhang; Hong-Mei Gu; Donna Situ; Anass Haimeur; SUSAN COLE; Roger G Deeley
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
The Journal of biological chemistry 2003;278(46):46052-63.
2003: Mario Muredda; Kenichi Nunoya; Ruth A Burtch-Wright; Ebba U Kurz; SUSAN COLE; Roger G Deeley
Cloning and Characterization of the Murine and Rat mrp1 Promoter Regions.
Molecular pharmacology 2003;64(5):1259-69.
2003: Lea Payen; Mian Gao; Christopher J Westlake; SUSAN COLE; Roger G Deeley
Role of carboxylate residues adjacent to the conserved core Walker B motifs in the catalytic cycle of multidrug resistance protein 1 (ABCC1).
The Journal of biological chemistry 2003;278(40):38537-47.
2003: Ken-ichi Ito; Kevin E Weigl; Roger G Deeley; SUSAN COLE
Mutation of proline residues in the NH(2)-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function.
Biochimica et biophysica acta 2003;1615(1-2):103-14.
2003: Da-Wei Zhang; Hong-Mei Gu; Monika Vasa; Mario Muredda; SUSAN COLE; Roger G Deeley
Characterization of the role of polar amino acid residues within predicted transmembrane helix 17 in determining the substrate specificity of multidrug resistance protein 3.
Biochemistry 2003;42(33):9989-10000.
2003: Katerina Neumann; K M Al-Batayneh; Michael Kuiper; J Parsons-Sheldrake; Michael G Tyshenko; W F Flintoff; SUSAN COLE; Virginia K Walker
A single point mutation in Drosophila dihydrofolate reductase confers methotrexate resistance to a transgenic CHO cell line.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 2003;46(4):707-15.
2003: Kenichi Nunoya; Caroline E Grant; Dawei Zhang; SUSAN COLE; Roger G Deeley
Molecular cloning and pharmacological characterization of rat multidrug resistance protein 1 (mrp1).
Drug metabolism and disposition: the biological fate of chemicals 2003;31(8):1016-26.
2003: Shelagh E L Mirski; Juliane C Bielawski; SUSAN COLE
Identification of functional nuclear export sequences in human topoisomerase IIalpha and beta.
Biochemical and biophysical research communications 2003;306(4):905-11.
2003: Elaine M Leslie; Isabelle J Létourneau; Roger G Deeley; SUSAN COLE
Functional and structural consequences of cysteine substitutions in the NH2 proximal region of the human multidrug resistance protein 1 (MRP1/ABCC1).
Biochemistry 2003;42(18):5214-24.
2003: Ilana Kogan; Mohabir Ramjeesingh; Canhui Li; Jackie F Kidd; Yanchun Wang; Elaine M Leslie; SUSAN COLE; Christine E Bear
CFTR directly mediates nucleotide-regulated glutathione flux.
The EMBO journal 2003;22(9):1981-9.
2003: Elaine M Leslie; Raymond J Bowers; Roger G Deeley; SUSAN COLE
Structural requirements for functional interaction of glutathione tripeptide analogs with the human multidrug resistance protein 1 (MRP1).
The Journal of pharmacology and experimental therapeutics 2003;304(2):643-53.
2003: Curtis J Oleschuk; Roger G Deeley; SUSAN COLE
Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3.
American journal of physiology. Gastrointestinal and liver physiology 2003;284(2):G280-9.
2003: Elaine M Leslie; Roger G Deeley; SUSAN COLE
Bioflavonoid stimulation of glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).
Drug metabolism and disposition: the biological fate of chemicals 2003;31(1):11-5.
2002: Koji Koike; Curtis J Oleschuk; Anass Haimeur; Sharon L Olsen; Roger G Deeley; SUSAN COLE
Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.
The Journal of biological chemistry 2002;277(51):49495-503.
2002: Chun-Nam Lok; Alexander J Lang; Shelagh E L Mirski; SUSAN COLE
Characterization of the human topoisomerase IIbeta (TOP2B) promoter activity: essential roles of the nuclear factor-Y (NF-Y)- and specificity protein-1 (Sp1)-binding sites.
The Biochemical journal 2002;368(Pt 3):741-51.
2002: Anass Haimeur; Roger G Deeley; SUSAN COLE
Charged amino acids in the sixth transmembrane helix of multidrug resistance protein 1 (MRP1/ABCC1) are critical determinants of transport activity.
The Journal of biological chemistry 2002;277(44):41326-33.
2002: Yue-Ming Qian; Caroline E Grant; Christopher J Westlake; Da-Wei Zhang; Peter A Lander; Robert L Shepard; Anne H Dantzig; SUSAN COLE; Roger G Deeley
Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione.
The Journal of biological chemistry 2002;277(38):35225-31.
2002: Qingcheng Mao; Wei Qiu; Kevin E Weigl; Peter A Lander; Linda Tabas; Robert L Shepard; Anne H Dantzig; Roger G Deeley; SUSAN COLE
GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776. Evidence of a major binding site in the COOH-proximal membrane spanning domain.
The Journal of biological chemistry 2002;277(32):28690-9.
2002: Da-Wei Zhang; SUSAN COLE; Roger G Deeley
Determinants of the substrate specificity of multidrug resistance protein 1: role of amino acid residues with hydrogen bonding potential in predicted transmembrane helix 17.
The Journal of biological chemistry 2002;277(23):20934-41.
2002: Silke Conrad; Hans-Martin Kauffmann; Ken-ichi Ito; Elaine M Leslie; Roger G Deeley; Dieter Schrenk; SUSAN COLE
A naturally occurring mutation in MRP1 results in a selective decrease in organic anion transport and in increased doxorubicin resistance.
Pharmacogenetics 2002;12(4):321-30.
2001: Yue-Ming Qian; Wei Qiu; Mian Gao; Christopher J Westlake; SUSAN COLE; Roger G Deeley
Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.
The Journal of biological chemistry 2001;276(42):38636-44.
2001: Ken-ichi Ito; Curtis J Oleschuk; Christopher J Westlake; Monika Vasa; Roger G Deeley; SUSAN COLE
Mutation of Trp1254 in the multispecific organic anion transporter, multidrug resistance protein 2 (MRP2) (ABCC2), alters substrate specificity and results in loss of methotrexate transport activity.
The Journal of biological chemistry 2001;276(41):38108-14.
2001: Elaine M Leslie; Roger G Deeley; SUSAN COLE
Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters.
Toxicology 2001;167(1):3-23.
2001: Da-Wei Zhang; SUSAN COLE; Roger G Deeley
Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.
The Journal of biological chemistry 2001;276(37):34966-74.
2001: Ebba U Kurz; SUSAN COLE; Roger G Deeley
Identification of DNA-protein interactions in the 5' flanking and 5' untranslated regions of the human multidrug resistance protein (MRP1) gene: evaluation of a putative antioxidant response element/AP-1 binding site.
Biochemical and biophysical research communications 2001;285(4):981-90.
2001: Elaine M Leslie; Ken-ichi Ito; P Upadhyaya; Stephen S Hecht; Roger G Deeley; SUSAN COLE
Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog.
The Journal of biological chemistry 2001;276(30):27846-54.
2001: LC Young; Barbara G Campling; SUSAN COLE; Roger G Deeley; JH Gerlach
Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1798-804.
2001: Ralph A Zirngibl; D Schulze; Shelagh E L Mirski; SUSAN COLE; Peter A Greer
Subcellular localization analysis of the closely related Fps/Fes and Fer protein-tyrosine kinases suggests a distinct role for Fps/Fes in vesicular trafficking.
Experimental cell research 2001;266(1):87-94.
2001: Mark F Rosenberg; Q Mao; Andreas Holzenburg; Robert C Ford; R G Deeley; SUSAN COLE
The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.
The Journal of biological chemistry 2001;276(19):16076-82.
2001: Ken-ichi Ito; S L Olsen; Wei Qiu; Roger G Deeley; SUSAN COLE
Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport.
The Journal of biological chemistry 2001;276(19):15616-24.
2001: Elaine M Leslie; Qingcheng Mao; Curtis J Oleschuk; Roger G Deeley; SUSAN COLE
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
Molecular pharmacology 2001;59(5):1171-80.
2001: Da-Wei Zhang; SUSAN COLE; Roger G Deeley
Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines.
The Journal of biological chemistry 2001;276(16):13231-9.
2001: Yue-Ming Qian; W C Song; H Cui; SUSAN COLE; Roger G Deeley
Glutathione stimulates sulfated estrogen transport by multidrug resistance protein 1.
The Journal of biological chemistry 2001;276(9):6404-11.
2001: Silke Conrad; Hans-Martin Kauffmann; K Ito; Roger G Deeley; SUSAN COLE; Dieter Schrenk
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.
Journal of human genetics 2001;46(11):656-63.
2000: Qingcheng Mao; Roger G Deeley; SUSAN COLE
Functional reconstitution of substrate transport by purified multidrug resistance protein MRP1 (ABCC1) in phospholipid vesicles.
The Journal of biological chemistry 2000;275(44):34166-72.
2000: DW Loe; Curtis J Oleschuk; Roger G Deeley; SUSAN COLE
Structure-activity studies of verapamil analogs that modulate transport of leukotriene C(4) and reduced glutathione by multidrug resistance protein MRP1.
Biochemical and biophysical research communications 2000;275(3):795-803.
2000: Shelagh E L Mirski; Theodora Voskoglou-Nomikos; LC Young; Roger G Deeley; Barbara G Campling; JH Gerlach; SUSAN COLE
Simultaneous quantitation of topoisomerase II alpha and beta isoform mRNAs in lung tumor cells and normal and malignant lung tissue.
Laboratory investigation; a journal of technical methods and pathology 2000;80(6):787-95.
2000: DW Loe; Roger G Deeley; SUSAN COLE
Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1).
The Journal of pharmacology and experimental therapeutics 2000;293(2):530-8.
2000: Mian Gao; H R Cui; DW Loe; Caroline E Grant; K C Almquist; SUSAN COLE; Roger G Deeley
Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.
The Journal of biological chemistry 2000;275(17):13098-108.
2000: Shelagh E L Mirski; Kathryn E Sparks; Q Yu; Alexander J Lang; N Jain; Barbara G Campling; SUSAN COLE
A truncated cytoplasmic topoisomerase IIalpha in a drug-resistant lung cancer cell line is encoded by a TOP2A allele with a partial deletion of exon 34.
International journal of cancer. Journal international du cancer 2000;85(4):534-9.
2000: Stefan Prechtl; M Roellinghoff; R Scheper; SUSAN COLE; Roger G Deeley; Michael Lohoff
The multidrug resistance protein 1: a functionally important activation marker for murine Th1 cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):754-61.
1999: DR Hipfner; Roger G Deeley; SUSAN COLE
Structural, mechanistic and clinical aspects of MRP1.
Biochimica et biophysica acta 1999;1461(2):359-76.
1999: Qingcheng Mao; Elaine M Leslie; Roger G Deeley; SUSAN COLE
ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells.
Biochimica et biophysica acta 1999;1461(1):69-82.
1999: Shelagh E L Mirski; JH Gerlach; SUSAN COLE
Sequence determinants of nuclear localization in the alpha and beta isoforms of human topoisomerase II.
Experimental cell research 1999;251(2):329-39.
1999: BD Stride; SUSAN COLE; Roger G Deeley
Localization of a substrate specificity domain in the multidrug resistance protein.
The Journal of biological chemistry 1999;274(32):22877-83.
1999: DR Hipfner; Qingcheng Mao; Wei Qiu; Elaine M Leslie; Mian Gao; Roger G Deeley; SUSAN COLE
Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. Localization of their epitopes to the nucleotide-binding domains of the protein.
The Journal of biological chemistry 1999;274(22):15420-6.
1999: SUSAN COLE
Re: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.
Journal of the National Cancer Institute 1999;91(10):888-9.
1999: Douglas Ross; W Yang; Lynne V Abruzzo; W S Dalton; E Schneider; H Lage; M Dietel; Lee M Greenberger; SUSAN COLE; L Austin Doyle
Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines.
Journal of the National Cancer Institute 1999;91(5):429-33.
1999: LC Young; Barbara G Campling; Theodora Voskoglou-Nomikos; SUSAN COLE; Roger G Deeley; JH Gerlach
Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(3):673-80.
1999: S Ruetz; M Brault; C Kast; C Hemenway; J Heitman; Caroline E Grant; SUSAN COLE; Roger G Deeley; Philippe Gros
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1999;274(4):2592.
1998: DW Loe; Roger G Deeley; SUSAN COLE
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.
Cancer research 1998;58(22):5130-6.
1998: B Savas; P E Kerr; H Ustun; SUSAN COLE; Hugh Pross
Lymphokine-activated killer cell susceptibility and multidrug resistance in small cell lung carcinoma.
Anticancer research 1998;18(6A):4355-61.
1998: SUSAN COLE; Roger G Deeley
Multidrug resistance mediated by the ATP-binding cassette transporter protein MRP.
BioEssays : news and reviews in molecular, cellular and developmental biology 1998;20(11):931-40.
1998: DR Hipfner; Mian Gao; G Scheffer; R J Scheper; Roger G Deeley; SUSAN COLE
Epitope mapping of monoclonal antibodies specific for the 190-kDa multidrug resistance protein (MRP).
British journal of cancer 1998;78(9):1134-40.
1998: Alexander J Lang; Shelagh E L Mirski; H J Cummings; Q Yu; JH Gerlach; SUSAN COLE
Structural organization of the human TOP2A and TOP2B genes.
Gene 1998;221(2):255-66.
1998: T Abe; T Mori; Y Wakabayashi; M Nakagawa; SUSAN COLE; K Koike; M Kuwano; S Hori
Expression of multidrug resistance protein gene in patients with glioma after chemotherapy.
Journal of neuro-oncology 1998;40(1):11-8.
1998: S R Wright; Alexander H Boag; Gunnar Valdimarsson; DR Hipfner; Barbara G Campling; SUSAN COLE; Roger G Deeley
Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(9):2279-89.
1998: Y Canitrot; F Bichat; SUSAN COLE; Roger G Deeley; JH Gerlach; Gérard Bastian; Francisco Arvelo; Marie-France Poupon
Multidrug resistance genes (MRP) and MDR1 expression in small cell lung cancer xenografts: relationship with response to chemotherapy.
Cancer letters 1998;130(1-2):133-41.
1998: Mian Gao; M Yamazaki; DW Loe; Christopher J Westlake; Caroline E Grant; SUSAN COLE; Roger G Deeley
Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4.
The Journal of biological chemistry 1998;273(17):10733-40.
1998: Michael Lohoff; Stefan Prechtl; Frank Sommer; M Roellinghoff; E Schmitt; G Gradehandt; Peter Rohwer; BD Stride; SUSAN COLE; Roger G Deeley
A multidrug-resistance protein (MRP)-like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo.
The Journal of clinical investigation 1998;101(3):703-10.
1998: Caroline E Grant; G Bhardwaj; SUSAN COLE; Roger G Deeley
Cloning, transfer, and characterization of multidrug resistance protein.
Methods in enzymology 1998;292():594-607.
1997: Shelagh E L Mirski; JH Gerlach; H J Cummings; Ralph A Zirngibl; Peter A Greer; SUSAN COLE
Bipartite nuclear localization signals in the C terminus of human topoisomerase II alpha.
Experimental cell research 1997;237(2):452-5.
1997: Irene Wessel; Peter B Jensen; J Falck; S E Mirski; SUSAN COLE; Maxwell Sehested
Loss of amino acids 1490Lys-Ser-Lys1492 in the COOH-terminal region of topoisomerase IIalpha in human small cell lung cancer cells selected for resistance to etoposide results in an extranuclear enzyme localization.
Cancer research 1997;57(20):4451-4.
1997: Caroline E Grant; Ebba U Kurz; SUSAN COLE; Roger G Deeley
Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA.
Genomics 1997;45(2):368-78.
1997: Murray D Norris; Sharon B Bordow; PS Haber; Glenn M Marshall; Maria Kavallaris; Janice Madafiglio; Susan Cohn; Helen R Salwen; Mary Lou Schmidt; DR Hipfner; SUSAN COLE; Roger G Deeley; Michelle Haber
Evidence that the MYCN oncogene regulates MRP gene expression in neuroblastoma.
European journal of cancer (Oxford, England : 1990) 1997;33(12):1911-6.
1997: DR Hipfner; K C Almquist; Elaine M Leslie; JH Gerlach; Caroline E Grant; Roger G Deeley; SUSAN COLE
Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.
The Journal of biological chemistry 1997;272(38):23623-30.
1997: H S Chan; T M Grogan; G Haddad; DR Hipfner; R G Deeley; SUSAN COLE
Standardization of a single-cell assay for sensitive detection of multidrug resistance protein expression in normal and malignant cells in archival clinical samples.
The Journal of laboratory and clinical medicine 1997;130(3):297-306.
1997: BD Stride; Caroline E Grant; DW Loe; DR Hipfner; SUSAN COLE; Roger G Deeley
Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells.
Molecular pharmacology 1997;52(3):344-53.
1997: Helen S L Chan; Y Lu; T M Grogan; G Haddad; DR Hipfner; SUSAN COLE; Roger G Deeley; V Ling; Brenda L Gallie
Multidrug resistance protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein.
Cancer research 1997;57(12):2325-30.
1997: Roger G Deeley; SUSAN COLE
Function, evolution and structure of multidrug resistance protein (MRP).
Seminars in cancer biology 1997;8(3):193-204.
1997: DW Loe; RK Stewart; Thomas E Massey; Roger G Deeley; SUSAN COLE
ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.
Molecular pharmacology 1997;51(6):1034-41.
1997: Q Yu; Shelagh E L Mirski; Kathryn E Sparks; SUSAN COLE
Two COOH-terminal truncated cytoplasmic forms of topoisomerase II alpha in a VP-16-selected lung cancer cell line result from partial gene deletion and alternative splicing.
Biochemistry 1997;36(19):5868-77.
1997: Masayuki Nakagawa; Akio Emoto; Nobuyoshi Nasu; Toshikatsu Hanada; M Kuwano; SUSAN COLE; Yoshio Nomura
Clinical significance of multi-drug resistance associated protein and P-glycoprotein in patients with bladder cancer.
The Journal of urology 1997;157(4):1260-4; discussion 1264-5.
1997: Barbara G Campling; LC Young; K A Baer; YM Lam; Roger G Deeley; SUSAN COLE; JH Gerlach
Expression of the MRP and MDR1 multidrug resistance genes in small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(1):115-22.
1996: B Savas; SUSAN COLE; T Tsuruo; H F Pross
P-glycoprotein-mediated multidrug resistance and lymphokine-activated killer cell susceptibility in ovarian carcinoma.
Journal of clinical immunology 1996;16(6):348-57.
1996: Mian Gao; DW Loe; Caroline E Grant; SUSAN COLE; Roger G Deeley
Reconstitution of ATP-dependent leukotriene C4 transport by Co-expression of both half-molecules of human multidrug resistance protein in insect cells.
The Journal of biological chemistry 1996;271(44):27782-7.
1996: D Lautier; Yvan Canitrot; Roger G Deeley; SUSAN COLE
Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.
Biochemical pharmacology 1996;52(7):967-77.
1996: DR Hipfner; K C Almquist; B D Stride; Roger G Deeley; SUSAN COLE
Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.
Cancer research 1996;56(14):3307-14.
1996: DW Loe; Roger G Deeley; SUSAN COLE
Biology of the multidrug resistance-associated protein, MRP.
European journal of cancer (Oxford, England : 1990) 1996;32A(6):945-57.
1996: B D Stride; G Valdimarsson; JH Gerlach; Gerald M Wilson; SUSAN COLE; Roger G Deeley
Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter.
Molecular pharmacology 1996;49(6):962-71.
1996: DW Loe; K C Almquist; SUSAN COLE; Roger G Deeley
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.
The Journal of biological chemistry 1996;271(16):9683-9.
1996: DW Loe; K C Almquist; Roger G Deeley; SUSAN COLE
Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport.
The Journal of biological chemistry 1996;271(16):9675-82.
1996: Inka Leier; Gabriele Jedlitschky; U Buchholz; M Center; SUSAN COLE; R G Deeley; Dietrich Keppler
ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump.
The Biochemical journal 1996;314 ( Pt 2)():433-7.
1996: S Ruetz; M Brault; C Kast; Charles S Hemenway; Joseph Heitman; Caroline E Grant; SUSAN COLE; Roger G Deeley; Philippe Gros
Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
The Journal of biological chemistry 1996;271(8):4154-60.
1996: A J Stewart; Yvan Canitrot; E Baracchini; Nicholas Dean; Roger G Deeley; SUSAN COLE
Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides.
Biochemical pharmacology 1996;51(4):461-9.
1996: B J Kuss; R G Deeley; SUSAN COLE; C L Willman; Kenneth J Kopecky; Sandra R Wolman; H J Eyre; David F Callen
The biological significance of the multidrug resistance gene MRP in inversion 16 leukemias.
Leukemia & lymphoma 1996;20(5-6):357-64.
1996: SUSAN COLE; R G Deeley
Multidrug resistance associated with overexpression of MRP.
Cancer treatment and research 1996;87():39-62.
1996: Douglas Ross; L Austin Doyle; Charles Alan Schiffer; Edward J Lee; Caroline E Grant; SUSAN COLE; Roger G Deeley; W Yang; Y Tong
Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients.
Leukemia 1996;10(1):48-55.
1995: Marilyn L Slovak; J P Ho; SUSAN COLE; Roger G Deeley; Lee M Greenberger; E G de Vries; Henk J Broxterman; G L Scheffer; R J Scheper
The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification.
Cancer research 1995;55(19):4214-9.
1995: Shelagh E L Mirski; SUSAN COLE
Cytoplasmic localization of a mutant M(r) 160,000 topoisomerase II alpha is associated with the loss of putative bipartite nuclear localization signals in a drug-resistant human lung cancer cell line.
Cancer research 1995;55(10):2129-34.
1995: S Hasegawa; Teruo Abe; S Naito; S Kotoh; J Kumazawa; DR Hipfner; Roger G Deeley; SUSAN COLE; Michihiko Kuwano
Expression of multidrug resistance-associated protein (MRP), MDR1 and DNA topoisomerase II in human multidrug-resistant bladder cancer cell lines.
British journal of cancer 1995;71(5):907-13.
1995: I Brock; DR Hipfner; Boye Nielsen; Peter B Jensen; Roger G Deeley; SUSAN COLE; Maxwell Sehested
Sequential coexpression of the multidrug resistance genes MRP and mdr1 and their products in VP-16 (etoposide)-selected H69 small cell lung cancer cells.
Cancer research 1995;55(3):459-62.
1995: K C Almquist; DW Loe; DR Hipfner; J E Mackie; SUSAN COLE; Roger G Deeley
Characterization of the M(r) 190,000 multidrug resistance protein (MRP) in drug-selected and transfected human tumor cell.
Cancer research 1995;55(1):102-10.
1994: SUSAN COLE; K E Sparks; K Fraser; DW Loe; Caroline E Grant; Gerald M Wilson; Roger G Deeley
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
Cancer research 1994;54(22):5902-10.
1994: DR Hipfner; S D Gauldie; Roger G Deeley; SUSAN COLE
Detection of the M(r) 190,000 multidrug resistance protein, MRP, with monoclonal antibodies.
Cancer research 1994;54(22):5788-92.
1994: Inka Leier; Gabriele Jedlitschky; U Buchholz; SUSAN COLE; R G Deeley; Dietrich Keppler
The MRP gene encodes an ATP-dependent export pump for leukotriene C4 and structurally related conjugates.
The Journal of biological chemistry 1994;269(45):27807-10.
1994: J D Jirsch; DW Loe; SUSAN COLE; Roger G Deeley; David Fedida
ATP is not required for anion current activated by cell swelling in multidrug-resistant lung cancer cells.
The American journal of physiology 1994;267(3 Pt 1):C688-99.
1994: Tomoyuki Sumizawa; Yutaka Chuman; H Sakamoto; K Iemura; K C Almquist; Roger G Deeley; SUSAN COLE; S Akiyama
Non-P-glycoprotein-mediated multidrug-resistant human KB cells selected in medium containing adriamycin, cepharanthine, and mezerein.
Somatic cell and molecular genetics 1994;20(5):423-35.
1994: B J Kuss; R G Deeley; SUSAN COLE; C L Willman; Kenneth J Kopecky; Sandra R Wolman; H J Eyre; S A Lane; J K Nancarrow; Scott A Whitmore
Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications.
Lancet 1994;343(8912):1531-4.
1994: P W Feldhoff; S E Mirski; SUSAN COLE; D M Sullivan
Altered subcellular distribution of topoisomerase II alpha in a drug-resistant human small cell lung cancer cell line.
Cancer research 1994;54(3):756-62.
1994: Caroline E Grant; G Valdimarsson; DR Hipfner; K C Almquist; SUSAN COLE; Roger G Deeley
Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs.
Cancer research 1994;54(2):357-61.
1994: C D Evans; Shelagh E L Mirski; M K Danks; SUSAN COLE
Reduced levels of topoisomerase II alpha and II beta in a multidrug-resistant lung-cancer cell line.
Cancer chemotherapy and pharmacology 1994;34(3):242-8.
1993: Shelagh E L Mirski; C D Evans; K C Almquist; Marilyn L Slovak; SUSAN COLE
Altered topoisomerase II alpha in a drug-resistant small cell lung cancer cell line selected in VP-16.
Cancer research 1993;53(20):4866-73.
1993: J Jirsch; Roger G Deeley; SUSAN COLE; A J Stewart; David Fedida
Inwardly rectifying K+ channels and volume-regulated anion channels in multidrug-resistant small cell lung cancer cells.
Cancer research 1993;53(18):4156-60.
1993: Barbara G Campling; K Baer; H M Baker; YM Lam; SUSAN COLE
Do glutathione and related enzymes play a role in drug resistance in small cell lung cancer cell lines?
British journal of cancer 1993;68(2):327-35.
1993: Marilyn L Slovak; J P Ho; G Bhardwaj; E U Kurz; Roger G Deeley; SUSAN COLE
Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.
Cancer research 1993;53(14):3221-5.
1993: SUSAN COLE; R G Deeley
Multidrug resistance-associated protein: sequence correction.
Science (New York, N.Y.) 1993;260(5110):879.
1993: K A Krebes; Shelagh E L Mirski; H F Pross; SUSAN COLE
Peripheral blood mononuclear cells express antigens associated with multidrug resistance in a small cell lung cancer cell line.
Anticancer research 1993;13(2):317-21.
1992: SUSAN COLE; G Bhardwaj; JH Gerlach; J E Mackie; Caroline E Grant; K C Almquist; A J Stewart; E U Kurz; AM Duncan; Roger G Deeley
Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line.
Science (New York, N.Y.) 1992;258(5088):1650-4.
1992: B Savas; SUSAN COLE; T F Akoglu; H F Pross
P-glycoprotein-mediated multidrug resistance and cytotoxic effector cells.
Natural immunity 1992;11(4):177-92.
1992: SUSAN COLE; M J Pinkoski; G Bhardwaj; Roger G Deeley
Elevated expression of annexin II (lipocortin II, p36) in a multidrug resistant small cell lung cancer cell line.
British journal of cancer 1992;65(4):498-502.
1992: SUSAN COLE
The 1991 Merck Frosst Award. Multidrug resistance in small cell lung cancer.
Canadian journal of physiology and pharmacology 1992;70(3):313-29.
1991: Marilyn L Slovak; Shelagh E L Mirski; SUSAN COLE; JH Gerlach; K H Yohem; Jeffrey M. Trent
Tumourigenic multidrug-resistant HT1080 cells do not overexpress receptors for epidermal growth factor.
British journal of cancer 1991;64(2):296-8.
1991: Shelagh E L Mirski; SUSAN COLE
Multidrug resistance-associated antigens on drug-sensitive and -resistant human tumour cell lines.
British journal of cancer 1991;64(1):15-22.
1991: SUSAN COLE; E R Chanda; F P Dicke; JH Gerlach; Shelagh E L Mirski
Non-P-glycoprotein-mediated multidrug resistance in a small cell lung cancer cell line: evidence for decreased susceptibility to drug-induced DNA damage and reduced levels of topoisomerase II.
Cancer research 1991;51(13):3345-52.
1991: Barbara G Campling; J Pym; H M Baker; SUSAN COLE; YM Lam
Chemosensitivity testing of small cell lung cancer using the MTT assay.
British journal of cancer 1991;63(1):75-83.
1991: SUSAN COLE; B M Campigotto; J G Johnson; Bruce E Elliott
Differential growth inhibition and enhancement of major histocompatibility complex class I antigen expression by interferons in a small-cell lung cancer cell line and its doxorubicin-selected multidrug-resistant variant.
Cancer immunology, immunotherapy : CII 1991;33(4):274-7.
1990: SUSAN COLE; S A Mohamdee; Shelagh E L Mirski
A monoclonal antibody detecting cell surface epitope on some drug resistant human tumour cell lines.
British journal of cancer 1990;62(1):14-6.
1990: SUSAN COLE; H F Downes; Shelagh E L Mirski; D J Clements
Alterations in glutathione and glutathione-related enzymes in a multidrug-resistant small cell lung cancer cell line.
Molecular pharmacology 1990;37(2):192-7.
1990: SUSAN COLE
Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line.
Cancer chemotherapy and pharmacology 1990;26(4):250-6.
1989: Shelagh E L Mirski; SUSAN COLE
Antigens associated with multidrug resistance in H69AR, a small cell lung cancer cell line.
Cancer research 1989;49(20):5719-24.
1989: Poh-Gek Forkert; M L Vessey; S S Park; H V Gelboin; SUSAN COLE
Cytochromes P-450 in murine lung. An immunohistochemical study with monoclonal antibodies.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(5):551-5.
1989: SUSAN COLE; H F Downes; M L Slovak
Effect of calcium antagonists on the chemosensitivity of two multidrug-resistant human tumour cell lines which do not overexpress P-glycoprotein.
British journal of cancer 1989;59(1):42-6.
1988: Barbara G Campling; J Pym; P R Galbraith; SUSAN COLE
Use of the MTT assay for rapid determination of chemosensitivity of human leukemic blast cells.
Leukemia research 1988;12(10):823-31.
1987: Shelagh E L Mirski; JH Gerlach; SUSAN COLE
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.
Cancer research 1987;47(10):2594-8.
1987: SUSAN COLE; E H Vreeken; S E Mirski; B G Campling
Growth of human x human hybridomas in protein-free medium supplemented with ethanolamine.
Journal of immunological methods 1987;97(1):29-35.
1986: SUSAN COLE; Barbara G Campling; D F Dexter; J J Holden; J C Roder
Establishment of a human large cell lung tumor line (QU-DB) with metastatic properties in athymic mice.
Cancer 1986;58(4):917-23.
1986: Poh-Gek Forkert; M L Vessey; J S Elce; S S Park; H V Gelboin; SUSAN COLE
Localization of phenobarbital- and 3-methylcholanthrene-inducible cytochromes P-450 in mouse lung with monoclonal antibodies.
Research communications in chemical pathology and pharmacology 1986;53(2):147-57.
1986: SUSAN COLE
Rapid chemosensitivity testing of human lung tumor cells using the MTT assay.
Cancer chemotherapy and pharmacology 1986;17(3):259-63.
1986: J C Roder; SUSAN COLE; D Kozbor
The EBV-hybridoma technique.
Methods in enzymology 1986;121():140-67.
1986: D Kozbor; J C Roder; M E Sierzega; SUSAN COLE; C M Croce
Comparative phenotypic analysis of available human hybridoma fusion partners.
Methods in enzymology 1986;121():120-40.
1985: SUSAN COLE; S Mirski; R C McGarry; R Cheng; B G Campling; J C Roder
Differential expression of the Leu-7 antigen on human lung tumor cells.
Cancer research 1985;45(9):4285-90.
1985: A C Peacock; S L Bunting; SUSAN COLE; M Seidman
Two-dimensional electrophoretic display of restriction fragments from genomic DNA.
Analytical biochemistry 1985;149(1):177-82.
1985: D Kozbor; W Abramow-Newerly; P Tripputi; SUSAN COLE; J Weibel; J C Roder; C M Croce
Specific immunoglobulin production and enhanced tumorigenicity following ascites growth of human hybridomas.
Journal of immunological methods 1985;81(1):31-42.
1985: SUSAN COLE; E H Vreeken; J C Roder
Antibody production by human X human hybridomas in serum-free medium.
Journal of immunological methods 1985;78(2):271-8.
1984: SUSAN COLE; G S Marks
Ferrochelatase and N-alkylated porphyrins.
Molecular and cellular biochemistry 1984;64(2):127-37.
1984: SUSAN COLE; B G Campling; I H Louwman; D Kozbor; J C Roder
A strategy for the production of human monoclonal antibodies reactive with lung tumor cell lines.
Cancer research 1984;44(7):2750-3.
1984: SUSAN COLE; B G Campling; T Atlaw; D Kozbor; J C Roder
Human monoclonal antibodies.
Molecular and cellular biochemistry 1984;62(2):109-20.
1983: G S Marks; S B Follows; D T Zelt; SUSAN COLE
Patterns of porphyrin accumulation in response to chemicals in chick embryo liver cells.
Canadian journal of physiology and pharmacology 1983;61(6):546-53.
1982: G S Marks; D T Zelt; SUSAN COLE
Alterations in the heme biosynthetic pathway as an index of exposure to toxins.
Canadian journal of physiology and pharmacology 1982;60(7):1017-26.
1982: SUSAN COLE; G S Marks; P R Oritz de Montellano; K L Kunze
Inhibition of ferrochelatase by N-methylprotoporphyrin IX is not accompanied by delta-aminolevulinic acid synthetase induction in chick embryo liver cell culture.
Canadian journal of physiology and pharmacology 1982;60(2):212-5.
1981: Paul R. Ortiz de Montellano; K L Kunze; SUSAN COLE; G S Marks
Differential inhibition of hepatic ferrochelatase by the isomers of N-ethylprotoporphyrin IX.
Biochemical and biophysical research communications 1981;103(2):581-6.
1981: SUSAN COLE; Thomas E Massey; Gerald S Marks; William J Racz
Effects of porphyrin-inducing drugs on ferrochelatase activity in isolated mouse hepatocytes.
Canadian journal of physiology and pharmacology 1981;59(11):1155-8.
1981: SUSAN COLE; R A Whitney; G S Marks
Ferrochelatase-inhibitory and porphyrin-inducing properties of 3,5-diethoxycarbonyl-1, 4-dihydro-2,4,6-trimethylpyridine and its analogues in chick embryo liver cells.
Molecular pharmacology 1981;20(2):395-403.
1981: SUSAN COLE; D T Zelt; G S Marks
Comparison of the effects of griseofulvin and 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on ferrochelatase activity in chick embryo liver.
Molecular pharmacology 1981;19(3):477-80.
1980: Paul R. Ortiz de Montellano; K L Kunze; SUSAN COLE; G S Marks
Inhibition of hepatic ferrochelatase by the four isomers of N-methylprotoporphyrin IX.
Biochemical and biophysical research communications 1980;97(4):1436-42.
1980: SUSAN COLE; G S Marks
Structural requirements in dihydropyridines for ferrochelatase inhibition and delta-aminolevulinic acid synthetase induction.
The International journal of biochemistry 1980;12(5-6):989-92.
1979: SUSAN COLE; E J Vavasour; G S Marks
Drug-induced porphyrin biosynthesis--XIX. Potentiation of the porphyrin-inducing effects of SKF 525-A in the chick embryo liver by 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine, an antihibitor of ferrochelatase.
Biochemical pharmacology 1979;28(24):0533-8.