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Laura Falasca

Research Profile

Chemicals & Drugs

Anatomy

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Microscopy, Electron

Physiology

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Alessandra Romagnoli; Roxane Simeone; Roland Brosch; Marco Corazzari; Giovanni Delogu; Marilena P Etna; Laura Falasca; Gian Maria Fimia; Valérie Gafa; Elena Giacomini; Delia Goletti; Manuela Pardini; Mauro Piacentini; Maria Elena Remoli; Eliana M Coccia
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
M D'Eletto; Laura Falasca; Maria Grazia Farrace; Gian Maria Fimia; G Di Giacomo; Gerry Melino; S Moreno; Roberta Nardacci; F Rossin; S Sepe; F Strappazzon; F Cecconi; Mauro Piacentini
Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins.
Jane L Armstrong; Marco Corazzari; Shaun Martin; Vittoria Pagliarini; Laura Falasca; David S Hill; Nicola Ellis; Salim Al Sabah; Christopher P F Redfern; Gian Maria Fimia; Mauro Piacentini; Penny E Lovat
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.

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All Publications

2012: Alessandra Romagnoli; Roxane Simeone; Roland Brosch; Marco Corazzari; Giovanni Delogu; Marilena P Etna; Laura Falasca; Gian Maria Fimia; Valérie Gafa; Elena Giacomini; Delia Goletti; Manuela Pardini; Mauro Piacentini; Maria Elena Remoli; Eliana M Coccia
ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells.
Autophagy 2012;8(9):1357-70.
2012: M D'Eletto; Laura Falasca; Maria Grazia Farrace; Gian Maria Fimia; G Di Giacomo; Gerry Melino; S Moreno; Roberta Nardacci; F Rossin; S Sepe; F Strappazzon; F Cecconi; Mauro Piacentini
Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins.
Cell death and differentiation 2012;19(7):1228-38.
2011: Jane L Armstrong; Marco Corazzari; Shaun Martin; Vittoria Pagliarini; Laura Falasca; David S Hill; Nicola Ellis; Salim Al Sabah; Christopher P F Redfern; Gian Maria Fimia; Mauro Piacentini; Penny E Lovat
Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(8):2216-26.
2010: Ivana Matic; Alessandra Sacchi; Alessandra Rinaldi; Gennaro Melino; Chaitan Khosla; Laura Falasca; Mauro Piacentini
Characterization of transglutaminase type II role in dendritic cell differentiation and function.
Journal of leukocyte biology 2010;88(1):181-8.
2009: Manuela D'Eletto; Maria Grazia Farrace; Laura Falasca; Valentina Reali; Serafina Oliverio; Gennaro Melino; Martin Griffin; Gian Maria Fimia; Mauro Piacentini
Transglutaminase 2 is involved in autophagosome maturation.
Autophagy 2009;5(8):1145-54.
2009: Beáta Tóth; Eva Garabuczi; Zsolt Sarang; György Vereb; György Vámosi; Daniel Aeschlimann; Bernadett Blaskó; Bálint Bécsi; Ferenc Erdõdi; Adam Lacy-Hulbert; Ailiang Zhang; Laura Falasca; Raymond B Birge; Zoltán Balajthy; Gerry Melino; László Fésüs; Zsuzsa Szondy
Transglutaminase 2 is needed for the formation of an efficient phagocyte portal in macrophages engulfing apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2084-92.
2008: Laura Falasca; Maria Grazia Farrace; Alessandra Rinaldi; Loretta Tuosto; Gerry Melino; Mauro Piacentini
Transglutaminase type II is involved in the pathogenesis of endotoxic shock.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(4):2616-24.
2008: Carlo Rodolfo; Laura Falasca; Giuseppina Di Giacomo; Pier Giorgio Mastroberardino; Mauro Piacentini
More than two sides of a coin? How to detect the multiple activities of type 2 transglutaminase.
Methods in enzymology 2008;442():201-12.
2006: Valentina Iadevaia; A Rinaldi; Laura Falasca; L P Pucillo; T Alonzi; G Chimini; Mauro Piacentini
ATP-binding cassette transporter 1 and transglutaminase 2 act on the same genetic pathway in the apoptotic cell clearance.
Cell death and differentiation 2006;13(11):1998-2001.
2006: Leonardo Baiocchi; Giuseppe Tisone; Laura Falasca; Claudia Telesca; Daniele Di Paolo; Giuseppe Orlando; Sonia Furfaro; Alessandro Anselmo; Marco Carbone; Mario Angelico
Assembly of biliary lipids in native hepatic bile after orthotopic liver transplantation: A biochemical and ultra-structural study in humans.
Hepatology research : the official journal of the Japan Society of Hepatology 2006;35(3):215-21.
2006: Licia Bordi; Concetta Castilletti; Laura Falasca; Fabiola Ciccosanti; Silvia Calcaterra; Gabriella Rozera; Antonino Di Caro; Stefania Zaniratti; A Rinaldi; Giuseppe Ippolito; Mauro Piacentini; Maria Rosaria Capobianchi
Bcl-2 inhibits the caspase-dependent apoptosis induced by SARS-CoV without affecting virus replication kinetics.
Archives of virology 2006;151(2):369-77.
2005: Laura Falasca; Valentina Iadevaia; Fabiola Ciccosanti; Gerry Melino; Annalucia Serafino; Mauro Piacentini
Transglutaminase type II is a key element in the regulation of the anti-inflammatory response elicited by apoptotic cell engulfment.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):7330-40.
2005: Mauro Piacentini; Alessandra Amendola; Fabiola Ciccosanti; Laura Falasca; Maria Grazia Farrace; Pier Giorgio Mastroberardino; Roberta Nardacci; Serafina Oliverio; Lucia Piredda; Carlo Rodolfo; Francesco Autuori
Type 2 transglutaminase and cell death.
Progress in experimental tumor research 2005;38():58-74.
2003: Zsuzsa Szondy; Zsolt Sarang; Peter Molnar; Tamas Nemeth; Mauro Piacentini; Pier Giorgio Mastroberardino; Laura Falasca; Daniel Aeschlimann; Judit Kovacs; Ildiko Kiss; Eva Szegezdi; Gabriella Lakos; Eva Rajnavolgyi; Paul J Birckbichler; Gerry Melino; Laszlo Fesus
Transglutaminase 2-/- mice reveal a phagocytosis-associated crosstalk between macrophages and apoptotic cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(13):7812-7.
2003: Roberta Nardacci; Oreste Lo Iacono; Fabiola Ciccosanti; Laura Falasca; Maria Addesso; Alessandra Amendola; Giorgio Antonucci; Antonio Craxì; Gian Maria Fimia; Valentina Iadevaia; Gerry Melino; Luigi Ruco; Guido Tocci; Giuseppe Ippolito; Mauro Piacentini
Transglutaminase type II plays a protective role in hepatic injury.
The American journal of pathology 2003;162(4):1293-303.
2003: Roberta Nardacci; Fabiola Ciccosanti; Laura Falasca; Oreste Lo Iacono; Alessandra Amendola; Giorgio Antonucci; Mauro Piacentini
Tissue transglutaminase in HCV infection.
Cell death and differentiation 2003;10 Suppl 1():S79-80.
2003: Laura Falasca; Fabiola Ciccosanti; Roberta Nardacci; Giorgio Antonucci; Mauro Piacentini
Trying to catch the HCV virus in its 'battle field'.
Cell death and differentiation 2003;10 Suppl 1():S77-8.
2002: Mauro Piacentini; Maria Grazia Farrace; Lucia Piredda; Paola Matarrese; Fabiola Ciccosanti; Laura Falasca; Carlo Rodolfo; Anna Maria Giammarioli; Elisabetta Verderio; Martin Griffin; Walter Malorni
Transglutaminase overexpression sensitizes neuronal cell lines to apoptosis by increasing mitochondrial membrane potential and cellular oxidative stress.
Journal of neurochemistry 2002;81(5):1061-72.
2002: Antonietta Nicotra; Laura Falasca; Ornella Senatori; Laura Conti Devirgiliis
Monoamine oxidase A and B activities in embryonic chick hepatocytes: differential regulation by retinoic acid.
Cell biochemistry and function 2002;20(2):87-94.
2001: Alessandra Amendola; Carlo Rodolfo; Antonino Di Caro; Fabiola Ciccosanti; Laura Falasca; Mauro Piacentini
"Tissue" transglutaminase expression in HIV-infected cells: an enzyme with an antiviral effect?
Annals of the New York Academy of Sciences 2001;946():108-20.
2001: Maxim Yu Grigoriev; Evgeny Suspitsin; Alexandr V Togo; Kazymir M Pozharisski; O A Ivanova; Roberta Nardacci; Laura Falasca; Mauro Piacentini; Evgeny N Imyanitov; Kaido P Hanson
Tissue transglutaminase expression in breast carcinomas.
Journal of experimental & clinical cancer research : CR 2001;20(2):265-8.
2001: Laura Falasca; Giuseppe Tisone; Giampiero Palmieri; Alessandro Anselmo; Daniele Di Paolo; Leonardo Baiocchi; E Torri; Giuseppe Orlando; Carlo U Casciani; Mario Angelico
Protective role of tauroursodeoxycholate during harvesting and cold storage of human liver: a pilot study in transplant recipients.
Transplantation 2001;71(9):1268-76.
2001: Laura Falasca; Alfredo Miccheli; E Sartori; Alberta Tomassini; Laura Conti Devirgiliis
Hepatocytes entrapped in alginate gel beads and cultured in bioreactor: rapid repolarization and reconstitution of adhesion areas.
Cells, tissues, organs 2001;168(3):126-36.
2001: Laura Falasca; A Felici; Mara Massimi; Luciana Dini; Laura Conti Devirgiliis
Retinoic acid modulates the asialoglycoprotein receptor expression in cultured fetal rat hepatocytes.
Mechanisms of ageing and development 2001;122(1):31-9.
2000: Giorgio Capuani; Alfredo Miccheli; Alberta Tomassini; Laura Falasca; Tommaso Aureli; Filippo Conti
Cellular volume determination of alginate-entrapped hepatocytes by MRI diffusion measurements.
Artificial cells, blood substitutes, and immobilization biotechnology 2000;28(4):293-305.
2000: Alfredo Miccheli; Alberta Tomassini; Giorgio Capuani; Maria Enrica Di Cocco; E Sartori; Laura Falasca; Laura Conti Devirgiliis; Cesare Manetti; Filippo Conti
Energy metabolism and re-establishment of intercellularadhesion complexes of gel entrapped hepatocytes.
Cytotechnology 2000;32(3):219-28.
2000: Laura Falasca; Giuseppe Tisone; Giuseppe Orlando; Leonardo Baiocchi; G Vennerecci; Alessandro Anselmo; E Torri; Daniele Di Paolo; F Strati; Carlo U Casciani; Mario Angelico
Tauroursodeoxycholate reduces ischemic damage in human allografts: a biochemical and ultrastructural study.
Transplantation proceedings 2000;32(1):49-50.
1999: Laura Falasca; P Marcellini; Carmen Ara; A Rufo; Laura Conti Devirgiliis
Growth inhibition and induction of specific hepatic phenotype expression by retinoic acid in HEPG2 cells.
Anticancer research 1999;19(4B):3283-92.
1998: Laura Falasca; A Favale; G Gualandi; G Maietta; Laura Conti Devirgiliis
Retinoic acid treatment induces apoptosis or expression of a more differentiated phenotype on different fractions of cultured fetal rat hepatocytes.
Hepatology (Baltimore, Md.) 1998;28(3):727-37.
1998: Luciana Dini; Laura Falasca; M T Ruzzittu; G Mossa; A Finazzi-Agrò; A Di Giulio
Interaction between isolated and purified liver cells and small unilamellar liposomes.
Liver 1998;18(4):229-38.
1998: Laura Falasca; A Favale; Annalucia Serafino; Carmen Ara; Laura Conti Devirgiliis
The effect of retinoic acid on the re-establishment of differentiated hepatocyte phenotype in primary culture.
Cell and tissue research 1998;293(2):337-47.
1998: Luciana Dini; M Ruzittu; Emanuela C Carlà; Laura Falasca
Relationship between cellular shape and receptor-mediated endocytosis: an ultrastructural and morphometric study in rat Kupffer cells.
Liver 1998;18(2):99-109.
1997: F Terenzi; Laura Falasca; M Marino; Rita Mele; G Velardi; Laura Conti Devirgiliis
Modulation of proliferative activity and amino acid transport in chick embryo hepatocytes by EGF and retinoic acid.
Cellular and molecular biology (Noisy-le-Grand, France) 1997;43(6):861-71.
1997: Alberto Bergamini; Luciana Dini; Leonardo Baiocchi; L Cappannoli; Laura Falasca; Francesca Bolacchi; Marcella Capozzi; E Faggioli; A Nistri; A Salanitro; L Ventura; Giovanni Rocchi; Mario Angelico
Bile acids with differing hydrophilic-hydrophobic properties do not influence cytokine production by human monocytes and murine Kupffer cells.
Hepatology (Baltimore, Md.) 1997;25(4):927-33.
1996: M Massimi; Laura Falasca; A Felici; Luciana Dini; Laura Conti Devirgiliis
Expression of the asialoglycoprotein receptor in cultured rat hepatocytes is modulated by cell density.
Bioscience reports 1996;16(6):477-84.
1996: Alberto Bergamini; Luciana Dini; Marcella Capozzi; Lina Ghibelli; Roberta Placido; E Faggioli; A Salanitro; E Buonanno; L Cappannoli; L Ventura; M Cepparulo; Laura Falasca; Giovanni Rocchi
Human immunodeficiency virus-induced cell death in cytokine-treated macrophages can be prevented by compounds that inhibit late stages of viral replication.
The Journal of infectious diseases 1996;173(6):1367-78.
1996: Laura Falasca; Alberto Bergamini; Annalucia Serafino; C Balabaud; Luciana Dini
Human Kupffer cell recognition and phagocytosis of apoptotic peripheral blood lymphocytes.
Experimental cell research 1996;224(1):152-62.
1996: Luciana Dini; Laura Falasca; Luisa Rossi; G Rotilio
In vivo uptake of Cu, Zn superoxide dismutase. Morphological evidence for preferential endocytosis and accumulation by sinusoidal liver cells.
Cellular and molecular biology (Noisy-le-Grand, France) 1996;42(2):269-77.
1996: Luciana Dini; M Ruzittu; Laura Falasca
Recognition and phagocytosis of apoptotic cells.
Scanning microscopy 1996;10(1):239-51; discussion 251-2.
1995: Laura Fiorucci; Fulvio Erba; Laura Falasca; Luciana Dini; Franca Ascoli
Localization and interaction of bovine pancreatic trypsin inhibitor and tryptase in the granules of bovine mast cells.
Biochimica et biophysica acta 1995;1243(3):407-13.
1995: Luciana Dini; Alessandro Lentini; G D Diez; M Rocha; Laura Falasca; L Serafino; Fernando Vidal-Vanaclocha
Phagocytosis of apoptotic bodies by liver endothelial cells.
Journal of cell science 1995;108 ( Pt 3)():967-73.
1994: Alberto Bergamini; Carlo Federico Perno; Luciana Dini; Marcella Capozzi; C D Pesce; L Ventura; L Cappannoli; Laura Falasca; G Milanese; Raffaele Caliò
Macrophage colony-stimulating factor enhances the susceptibility of macrophages to infection by human immunodeficiency virus and reduces the activity of compounds that inhibit virus binding.
Blood 1994;84(10):3405-12.
1993: Luciana Dini; Laura Falasca; Alessandro Lentini; P Mattioli; Mauro Piacentini; Lucia Piredda; Francesco Autuori
Galactose-specific receptor modulation related to the onset of apoptosis in rat liver.
European journal of cell biology 1993;61(2):329-37.
1992: Alessandro Lentini; Laura Falasca; Francesco Autuori; Luciana Dini
The simultaneous exposition of galactose and mannose-specific receptors on rat liver macrophages is developmentally regulated.
Bioscience reports 1992;12(6):453-61.
1992: Laura Falasca; Alessandro Lentini; Luciana Dini
Receptor mediated endocytosis of N-acetylglucosamine and mannose exposing molecules by cultured chick embryo hepatocytes.
Cellular and molecular biology (Noisy-le-Grand, France) 1992;38(5-6):621-7.
1991: Laura Falasca; P Mattioli; Luciana Dini
Chick hepatic lectins: an electron microscopic study on isolated hepatocytes during development.
Bioscience reports 1991;11(5):257-64.