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Douglas McHugh

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TOP 3
Douglas McHugh
GPR18 in microglia: implications for the CNS and endocannabinoid system signalling.
Douglas McHugh; Jeremy Page; Emily Dunn; Heather B Bradshaw
Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
Douglas McHugh; Jeremy Page; James Wager-Miller; Heather B Bradshaw
siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration.

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All Publications

2012: Douglas McHugh
GPR18 in microglia: implications for the CNS and endocannabinoid system signalling.
British journal of pharmacology 2012;167(8):1575-82.
2012: Douglas McHugh; Jeremy Page; Emily Dunn; Heather B Bradshaw
Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
British journal of pharmacology 2012;165(8):2414-24.
2012: Douglas McHugh; Jeremy Page; James Wager-Miller; Heather B Bradshaw
siRNA knockdown of GPR18 receptors in BV-2 microglia attenuates N-arachidonoyl glycine-induced cell migration.
Journal of molecular signaling 2012;7(1):10.
2010: Douglas McHugh; Sherry S J Hu; Neta Rimmerman; Ana Juknat; Zvi Vogel; J Michael Walker; Heather B Bradshaw
N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.
BMC neuroscience 2010;11():44.
2009: Heather B Bradshaw; Sung Ha Lee; Douglas McHugh
Orphan endogenous lipids and orphan GPCRs: a good match.
Prostaglandins & other lipid mediators 2009;89(3-4):131-4.
2009: Douglas McHugh; Ruth A Ross
Endogenous cannabinoids and neutrophil chemotaxis.
Vitamins and hormones 2009;81():337-65.
2008: Neta Rimmerman; Heather B Bradshaw; H Velocity Hughes; Jay Shih-Chieh Chen; Sherry Shu-Jung Hu; Douglas McHugh; Eivind Vefring; Jan A Jahnsen; Eric L Thompson; Kim Masuda; Benjamin F Cravatt; Sumner Burstein; Michael R Vasko; Anne L Prieto; David K O'Dell; J Michael Walker
N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.
Molecular pharmacology 2008;74(1):213-24.
2008: Douglas McHugh; Carolyn Tanner; Urij Rampampam; Roger G Pertwee; Ruth A Ross
Inhibition of human neutrophil chemotaxis by endogenous cannabinoids and phytocannabinoids: evidence for a site distinct from CB1 and CB2.
Molecular pharmacology 2008;73(2):441-50.
2007: Marina Rubio; Douglas McHugh; Javier Fernández-Ruiz; Heather B Bradshaw; J Michael Walker
Short-term exposure to alcohol in rats affects brain levels of anandamide, other N-acylethanolamines and 2-arachidonoyl-glycerol.
Neuroscience letters 2007;421(3):270-4.
2006: Douglas McHugh; R Shannon McMaster; Roger G Pertwee; Sucharita Roy; Anu Mahadevan; Raj K Razdan; Ruth A Ross
Novel compounds that interact with both leukotriene B4 receptors and vanilloid TRPV1 receptors.
The Journal of pharmacology and experimental therapeutics 2006;316(2):955-65.