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William Murphy

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Kai Sun; Lisbeth A Welniak; Chien-Chun Pai; Mehrdad Abedi; Erik Ames; Bruce R Blazar; Myriam Bouchlaka; Mingyi Chen; Takeshi Hagino; Hui-Hua Hsiao; Jared Jagdeo; Minghui Li; William Murphy
IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.
Arta M Monjazeb; Hui-Hua Hsiao; Gail D Sckisel; William Murphy
The role of antigen-specific and non-specific immunotherapy in the treatment of cancer.
Bruce R Blazar; William Murphy; Mehrdad Abedi
Advances in graft-versus-host disease biology and therapy.

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2012: Kai Sun; Lisbeth A Welniak; Chien-Chun Pai; Mehrdad Abedi; Erik Ames; Bruce R Blazar; Myriam Bouchlaka; Mingyi Chen; Takeshi Hagino; Hui-Hua Hsiao; Jared Jagdeo; Minghui Li; William Murphy
IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(4):2033-42.
2012: Arta M Monjazeb; Hui-Hua Hsiao; Gail D Sckisel; William Murphy
The role of antigen-specific and non-specific immunotherapy in the treatment of cancer.
Journal of immunotoxicology 2012;9(3):248-58.
2012: Bruce R Blazar; William Murphy; Mehrdad Abedi
Advances in graft-versus-host disease biology and therapy.
Nature reviews. Immunology 2012;12(6):443-58.
2012: William Murphy; Jan A Nolta
Autoimmune T cells lured to a FASL web of death by MSCs.
Cell stem cell 2012;10(5):485-7.
2012: Julia K Tietze; Jonathan M Weiss; Danice E C Wilkins; Robert H Wiltrout; Doug Redelman; Gail D Sckisel; Kory L Alderson; Erik Ames; Bruce R Blazar; Myriam N Bouchlaka; Kevin W Bruhn; Noah Craft; Lewis L Lanier; Dan L Longo; William Murphy
Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy.
Blood 2012;119(13):3073-83.
2012: Erik Ames; Salif Harouna; Colin Meyer; Lisbeth A Welniak; William Murphy
The triterpenoid CDDO-Me promotes hematopoietic progenitor expansion and myelopoiesis in mice.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(3):396-405.
2012: Kai Sun; Doug Redelman; Maite Alvarez; Erik Ames; Isabel Barao; Mingyi Chen; Dan L Longo; William Murphy
Mouse NK cell-mediated rejection of bone marrow allografts exhibits patterns consistent with Ly49 subset licensing.
Blood 2012;119(6):1590-8.
2012: Mathangi Srinivasan; Patricia A Taylor; Joseph H Antin; Jeffrey L Browning; Ryan Flynn; Leo Luznik; William Murphy; Angela Panoskaltsis-Mortari; Andrew Price; Ann Ranger; Jerome Ritz; Mark J Shlomchik; Bruce R Blazar
Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans.
Blood 2012;119(6):1570-80.
2012: Myriam N Bouchlaka; Cahit A Evrensel; Alan Fuchs; Maxwell A Fung; Emanual Maverakis; Arta M Monjazeb; Doug Redelman; Gail D Sckisel; Lisbeth Welniak; Danice Wilkins; William Murphy
Mechanical disruption of tumors by iron particles and magnetic field application results in increased anti-tumor immune responses.
PloS one 2012;7(10):e48049.
2012: William Murphy; Peter Parham; Jeffrey S Miller
NK cells--from bench to clinic.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2012;18(1 Suppl):S2-7.
2011: Isabel Barao; Maite Alvarez; John R Ortaldo; Doug Redelman; Jonathan M Weiss; Robert H Wiltrout; William Murphy
Hydrodynamic delivery of human IL-15 cDNA increases murine natural killer cell recovery after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2011;17(12):1754-64.
2011: Julia K Tietze; Gail D Sckisel; Hui-Hua Hsiao; William Murphy
Antigen-specific versus antigen-nonspecific immunotherapeutic approaches for human melanoma: the need for integration for optimal efficacy?
International reviews of immunology 2011;30(5-6):238-93.
2011: Isabel Barao; Bruce R Blazar; Lewis L Lanier; Maite Alvarez; Erik Ames; Stephen K Anderson; Mark T Orr; Doug Redelman; Heather Emily Stefanski; William Murphy
Mouse Ly49G2+ NK cells dominate early responses during both immune reconstitution and activation independently of MHC.
Blood 2011;117(26):7032-41.
2011: Qing Zhou; Meghan E Munger; Rachelle G Veenstra; Brenda J Weigel; Mitsuomi Hirashima; David H Munn; William Murphy; Miyuki Azuma; Ana C Anderson; Vijay K Kuchroo; Bruce R Blazar
Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.
Blood 2011;117(17):4501-10.
2011: James M Coghill; Stefanie Sarantopoulos; Timothy P Moran; William Murphy; Bruce R Blazar; Jonathan S Serody
Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new.
Blood 2011;117(12):3268-76.
2011: Bernard A Fox; Thomas F Gajewski; Jerome Galon; Jared A Gollob; Cécile Gouttefangeas; Fabio Grizzi; Michele Guida; Leif Håkansson; Kristen Hege; Ronald B Herberman; F Stephen Hodi; Axel Hoos; Christoph Huber; Patrick Hwu; Kohzoh Imai; Elizabeth M Jaffee; Sylvia Janetzki; Carl H June; Pawel Kalinski; Howard L Kaufman; Koji Kawakami; Yutaka Kawakami; Ulrich Keilholtz; Samir N Khleif; Rolf Kiessling; Beatrix Kotlan; Guido Kroemer; Rejean Lapointe; Hyam I Levitsky; Michael T Lotze; Cristina Maccalli; Michele Maio; Francesco M Marincola; Jens-Peter Marschner; Michael J Mastrangelo; Giuseppe Masucci; Ignacio Melero; Cornelius Melief; William Murphy; Brad Nelson; Andrea Nicolini; Michael I Nishimura; Jill O'Donnell-Tormey; Kunle Odunsi; Pamela S Ohashi; Lloyd J Old; Christian Ottensmeier; Michael Papamichail; Giorgio Parmiani; Graham Pawelec; Enrico Proietti; Shukui Qin; Robert Rees; Antoni Ribas; Ruggero Ridolfi; Gerd Ritter; Licia Rivoltini; Pedro J Romero; Mohamed L Salem; Dolores J Schendel; Rik J Scheper; Barbara Seliger; Padmanee Sharma; Hiroshi Shiku; Harpreet Singh-Jasuja; Wenru Song; Per Thor Straten; Hideaki Tahara; Zhigang Tian; Sjoerd H van der burg; Paul von Hoegen; Ena Wang; Marij Jp Welters; JON WIGGINTON; Hauke Winter; Tara Withington; Jedd D Wolchok; Weihua Xiao; Laurence Zitvogel; Heinz Zwierzina; Steinar Aamdal; James P Allison; Paolo Antonio Ascierto; Michael B Atkins; Jirina Bartunkova; Lothar Bergmann; Neil Berinstein; Cristina C Bonorino; Ernest Borden; Jonathan L Bramson; Cedrik M Britten; Lisa H Butterfield; Xuetao Cao; William E Carson; Alfred E Chang; Dainius Characiejus; A Raja Choudhury; George Coukos; Tanja de Gruijl; Robert O Dillman; Harry Dolstra; Glenn Dranoff; Lindy G Durrant; James H Finke; Mary L Disis
Defining the critical hurdles in cancer immunotherapy.
Journal of translational medicine 2011;9(1):214.
2010: Jonathan M Weiss; Lisa A Ridnour; Tim Back; S Perwez Hussain; Peijun He; Anna E Maciag; Larry K Keefer; William Murphy; Curtis C Harris; David A Wink; Robert H Wiltrout
Macrophage-dependent nitric oxide expression regulates tumor cell detachment and metastasis after IL-2/anti-CD40 immunotherapy.
The Journal of experimental medicine 2010;207(11):2455-67.
2010: Qing Zhou; Meghan E Munger; Steven L Highfill; Jakub Tolar; Brenda J Weigel; Megan Riddle; Arlene H Sharpe; Daniel A Vallera; Miyuki Azuma; Bruce L Levine; Carl H June; William Murphy; David H Munn; Bruce R Blazar
Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.
Blood 2010;116(14):2484-93.
2010: Dennis D Taub; William Murphy; Dan L Longo
Rejuvenation of the aging thymus: growth hormone-mediated and ghrelin-mediated signaling pathways.
Current opinion in pharmacology 2010;10(4):408-24.
2010: Maite Urbieta; Isabel Barao; Monica Jones; Roland Jurecic; Angela Panoskaltsis-Mortari; Bruce R Blazar; William Murphy; Robert B Levy
Hematopoietic progenitor cell regulation by CD4+CD25+ T cells.
Blood 2010;115(23):4934-43.
2010: Minghui Li; Kai Sun; Doug Redelman; Lisbeth A Welniak; William Murphy
The triterpenoid CDDO-Me delays murine acute graft-versus-host disease with the preservation of graft-versus-tumor effects after allogeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(6):739-50.
2010: Bo Hu; Yan He; Yan Wu; Guangming Bao; Haiyan Liu; Lisbeth A Welniak; William Murphy
Activated allogeneic NK cells as suppressors of alloreactive responses.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(6):772-81.
2010: Myriam N Bouchlaka; Doug Redelman; William Murphy
Immunotherapy following hematopoietic stem cell transplantation: potential for synergistic effects.
Immunotherapy 2010;2(3):399-418.
2010: Jeffrey S Miller; Edus H Warren; Marcel R M van den Brink; Jerome Ritz; Warren D Shlomchik; William Murphy; A John Barrett; Hans Jochem Kolb; Sergio Giralt; Michael R Bishop; Bruce R Blazar; J H Frederik Falkenburg
NCI First International Workshop on The Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biology Underlying Recurrence of Malignant Disease following Allogeneic HSCT: Graft-versus-Tumor/Leukemia Reaction.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(5):565-86.
2010: Mark T Orr; William Murphy; Lewis L Lanier
'Unlicensed' natural killer cells dominate the response to cytomegalovirus infection.
Nature immunology 2010;11(4):321-7.
2010: Kory L Alderson; William Murphy
Antigen specific memory T cells and their putative need for the generation of sustained anti-tumor responses.
Advances in experimental medicine and biology 2010;684():155-65.
2009: William Murphy; Andrew S Artz; Richard E Champlin; John Koreth; Dan L Longo; Marcel R M van den Brink
Blood stem cell transplantation in older patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(12):1638-9.
2009: John Koreth; Edwin P Alyea; William Murphy; Lisbeth A Welniak
Proteasome inhibition and allogeneic hematopoietic stem cell transplantation: a review.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009;15(12):1502-12.
2009: Jonathan M Weiss; Timothy C Back; Anthony J Scarzello; Jeffrey Subleski; Veronica L Hall; Jimmy K Stauffer; Xin Chen; Dejan Micic; Kory Alderson; William Murphy; Robert Wiltrout
Successful immunotherapy with IL-2/anti-CD40 induces the chemokine-mediated mitigation of an immunosuppressive tumor microenvironment.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19455-60.
2009: Matthew J O'Shaughnessy; C Vogtenhuber; K Sun; R Sitcheran; A S Baldwin; William Murphy; L Dang; B Jaffee; E Palmer; Jonathan S Serody; Bruce R Blazar
Ex vivo inhibition of NF-kappaB signaling in alloreactive T-cells prevents graft-versus-host disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(3):452-62.
2009: E Ames; William H D Hallett; William Murphy
Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition.
Clinical and experimental immunology 2009;155(3):504-13.
2009: Kory L Alderson; William Murphy
Effects of cancer immunotherapy regimens on primary vs. secondary immune responses and the potential impact on long-term antitumor responses.
Advances in experimental medicine and biology 2009;633():81-9.
2008: William Murphy
Raising the spectra of T-cell profiling.
Blood 2008;112(8):3008-9.
2008: Patricia A Taylor; Michael J Ehrhardt; Christopher J Lees; Angela Panoskaltsis-Mortari; Arthur M Krieg; Arlene H Sharpe; William Murphy; Jonathan S Serody; Hiroaki Hemmi; Shizuo Akira; Robert B Levy; Bruce R Blazar
TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection.
Blood 2008;112(8):3508-16.
2008: William H D Hallett; Erik Ames; Maite Alvarez; Isabel Barao; Patricia A Taylor; Bruce R Blazar; William Murphy
Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(10):1088-99.
2008: Minghui Li; Kai Sun; Lisbeth A Welniak; William Murphy
Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease.
Expert opinion on pharmacotherapy 2008;9(13):2305-16.
2008: Kai Sun; Minghui Li; Thomas J Sayers; Lisbeth A Welniak; William Murphy
Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation.
Blood 2008;112(4):1522-9.
2008: Roman Puliaev; Irina Puliaeva; Lisbeth A Welniak; Abigail E Ryan; Mark Haas; William Murphy; Charles S Via
CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(1):47-61.
2008: Anil Shanker; Alan David Brooks; Carlos Alberto Tristan; John William Wine; Peter John Elliott; Hideo Yagita; Kazuyoshi Takeda; Mark John Smyth; William Murphy; Thomas Joseph Sayers
Treating metastatic solid tumors with bortezomib and a tumor necrosis factor-related apoptosis-inducing ligand receptor agonist antibody.
Journal of the National Cancer Institute 2008;100(9):649-62.
2008: Doug Redelman; Lisbeth A Welniak; Dennis Taub; William Murphy
Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network.
Cellular immunology 2008;252(1-2):111-21.
2008: Kory L Alderson; Qing Zhou; Vanessa Berner; Danice E C Wilkins; Jonathan M Weiss; Bruce R Blazar; Lisbeth A Welniak; Robert Wiltrout; Doug Redelman; William Murphy
Regulatory and conventional CD4+ T cells show differential effects correlating with PD-1 and B7-H1 expression after immunotherapy.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):2981-8.
2008: William H D Hallett; Erik Ames; Milad Motarjemi; Isabel Barao; Anil Shanker; David L Tamang; Thomas J Sayers; Dorothy Hudig; William Murphy
Sensitization of tumor cells to NK cell-mediated killing by proteasome inhibition.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):163-70.
2007: Kai Sun; Minghui Li; Marina Konopleva; Sergej Konoplev; L Clifton Stephens; Steven M Kornblau; Olga Frolova; Danice E C Wilkins; Weihong Ma; Lisbeth A Welniak; Michael Andreeff; William Murphy
The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(5):521-9.
2007: Qing Zhou; Ruth A Gault; Thomas R Kozel; William Murphy
Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5753-61.
2007: Lauren H Mattingly; Ruth A Gault; William Murphy
Use of systemic proteasome inhibition as an immune-modulating agent in disease.
Endocrine, metabolic & immune disorders drug targets 2007;7(1):29-34.
2007: Vanessa Berner; Haiyan Liu; Qing Zhou; Kory L Alderson; Kai Sun; Jonathan M Weiss; Timothy C Back; Dan Longo; Bruce R Blazar; Robert Wiltrout; Lisbeth A Welniak; Doug Redelman; William Murphy
IFN-gamma mediates CD4+ T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy.
Nature medicine 2007;13(3):354-60.
2007: Lisbeth A Welniak; Bruce R Blazar; William Murphy
Immunobiology of allogeneic hematopoietic stem cell transplantation.
Annual review of immunology 2007;25():139-70.
2006: Zhao Wang; William Murphy
[Relationship between CCR5 and acute graft-versus-host disease in murine bone marrow transplantation].
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology 2006;14(5):934-40.
2006: William H D Hallett; William Murphy
Positive and negative regulation of Natural Killer cells: therapeutic implications.
Seminars in cancer biology 2006;16(5):367-82.
2006: Lynnette Shorts; Jonathan M Weiss; Jong-Keuk Lee; Lisbeth A Welniak; Jeffrey Subleski; Timothy C Back; William Murphy; Robert Wiltrout
Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6543-52.
2006: Isabel Barao; Alan M Hanash; William H D Hallett; Lisbeth A Welniak; Kai Sun; Doug Redelman; Bruce R Blazar; Robert B Levy; William Murphy
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(14):5460-5.
2006: Qing Zhou; Ruth A Gault; Thomas R Kozel; William Murphy
Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis.
Infection and immunity 2006;74(4):2161-8.
2006: Qing Zhou; William Murphy
Immune response and immunotherapy to Cryptococcus infections.
Immunologic research 2006;35(3):191-208.
2006: Lisbeth A Welniak; Dmitry V Kuprash; Alexei Tumanov; Angela Panoskaltsis-Mortari; Bruce R Blazar; Kai Sun; Sergei A Nedospasov; William Murphy
Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation.
Blood 2006;107(1):410-2.
2006: Thomas J Sayers; William Murphy
Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy.
Cancer immunology, immunotherapy : CII 2006;55(1):76-84.
2005: Alan D Brooks; Teresa Ramirez; Uhi Toh; Jennifer Onksen; Peter J Elliott; William Murphy; Thomas J Sayers
The proteasome inhibitor bortezomib (Velcade) sensitizes some human tumor cells to Apo2L/TRAIL-mediated apoptosis.
Annals of the New York Academy of Sciences 2005;1059():160-7.
2005: Kai Sun; Danice E C Wilkins; Miriam R Anver; Thomas J Sayers; Angela Panoskaltsis-Mortari; Bruce R Blazar; Lisbeth A Welniak; William Murphy
Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity.
Blood 2005;106(9):3293-9.
2005: Bruce R Blazar; William Murphy
Bone marrow transplantation and approaches to avoid graft-versus-host disease (GVHD).
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1461):1747-67.
2005: John R Ortaldo; Robin Winkler-Pickett; Earl W Bere; Morihiro Watanabe; William Murphy; Robert Wiltrout
In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):693-9.
2005: Jong-Keuk Lee; Naoko Seki; Thomas J Sayers; Jeffrey Subleski; E M Gruys; William Murphy; Robert Wiltrout
Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L.
Cellular immunology 2005;235(2):145-52.
2005: Dmitry V Kuprash; Alexei Tumanov; Dmitry J Liepinsh; Ekaterina P Koroleva; Marina S Drutskaya; Andrei A Kruglov; Alexander N Shakhov; Eileen Southon; William Murphy; Lino Tessarollo; Sergei Grivennikov; Sergei A Nedospasov
Novel tumor necrosis factor-knockout mice that lack Peyer's patches.
European journal of immunology 2005;35(5):1592-600.
2005: Crystal Y Koh; Lisbeth A Welniak; William Murphy
Lack of correlation between an assay used to determine early marrow allograft rejection and long-term chimerism after murine allogeneic bone marrow transplantation: effects of marrow dose.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(4):252-9.
2005: Maria Gendelman; Nadine Halligan; Richard A Komorowski; Brent Logan; William Murphy; Bruce R Blazar; Kirkwood A Pritchard; William R Drobyski
Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration.
Blood 2005;105(1):428-31.
2004: William Murphy; Pavel A Pevzner; Stephen J O'Brien
Mammalian phylogenomics comes of age.
Trends in genetics : TIG 2004;20(12):631-9.
2004: Lisbeth A Welniak; Lynnette Shorts; Jeffrey Subleski; Bruce R Blazar; Robert Wiltrout; William Murphy
Tumor regression by anti-CD40 and interleukin-2: role of CD40 in hematopoietic cells and organ-specific effects.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(8):534-9.
2004: Kai Sun; Lisbeth A Welniak; Angela Panoskaltsis-Mortari; Matthew J O'Shaughnessy; Haiyan Liu; Isabel Barao; William Riordan; Raquel Sitcheran; Christian Wysocki; Jonathan S Serody; Bruce R Blazar; Thomas J Sayers; William Murphy
Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):8120-5.
2004: Thomas R Kozel; William Murphy; Suzanne Brandt; Bruce R Blazar; Julie Lovchik; Peter Thorkildson; Ann Percival; C Rick Lyons
mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):5042-7.
2004: Lisbeth A Welniak; Zhao Wang; Kai Sun; William Kuziel; Miriam R Anver; Bruce R Blazar; William Murphy
An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease.
Experimental hematology 2004;32(3):318-24.
2004: William H D Hallett; William Murphy
Natural killer cells: biology and clinical use in cancer therapy.
Cellular & molecular immunology 2004;1(1):12-21.
2004: John R Ortaldo; Howard A Young; Robin Winkler-Pickett; Earl W Bere; William Murphy; Robert Wiltrout
Dissociation of NKT stimulation, cytokine induction, and NK activation in vivo by the use of distinct TCR-binding ceramides.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(2):943-53.
2004: Lisbeth A Welniak; Michael Karas; Shoshana Yakar; Miriam R Anver; William Murphy; Derek LeRoith
Effects of organ-specific loss of insulin-like growth factor-I production on murine hematopoiesis.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2004;10(1):32-9.
2003: Isabel Barao; William Murphy
The immunobiology of natural killer cells and bone marrow allograft rejection.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(12):727-41.
2003: Crystal Y Koh; John R Ortaldo; Bruce R Blazar; Michael Bennett; William Murphy
NK-cell purging of leukemia: superior antitumor effects of NK cells H2 allogeneic to the tumor and augmentation with inhibitory receptor blockade.
Blood 2003;102(12):4067-75.
2003: Kenneth Dorshkind; Lisbeth A Welniak; Ruth A Gault; Julie A Hixon; Encarnacion Montecino-Rodriguez; Nelson D Horseman; Joseph M Gertner; William Murphy
Effects of housing on the thymic deficiency in dwarf mice and its reversal by growth hormone administration.
Clinical immunology (Orlando, Fla.) 2003;109(2):197-202.
2003: Rosalba Salcedo; Xia Zhang; Howard A Young; Nelson Michael; Ken Wasserman; Wei-Hong Ma; Manuela Martins-Green; William Murphy; Joost J Oppenheim
Angiogenic effects of prostaglandin E2 are mediated by up-regulation of CXCR4 on human microvascular endothelial cells.
Blood 2003;102(6):1966-77.
2003: Rui Sun; Ruth A Gault; Lisbeth A Welniak; Zhigang G Tian; Susan Richards; William Murphy
Immunologic and hematopoietic effects of recombinant human prolactin after syngeneic bone marrow transplantation in mice.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2003;9(7):426-34.
2003: Thomas J Sayers; Alan D Brooks; Crystal Y Koh; Weihong Ma; Naoko Seki; Arati Raziuddin; Bruce R Blazar; Xia Zhang; Peter J Elliott; William Murphy
The proteasome inhibitor PS-341 sensitizes neoplastic cells to TRAIL-mediated apoptosis by reducing levels of c-FLIP.
Blood 2003;102(1):303-10.
2003: Zong-ming Chen; Matthew J O'Shaughnessy; Irene Gramaglia; Angela Panoskaltsis-Mortari; William Murphy; Satwant Narula; Maria G Roncarolo; Bruce R Blazar
IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function.
Blood 2003;101(12):5076-83.
2003: William Murphy; Lisbeth A Welniak; Timothy C Back; Julie A Hixon; Jeffrey Subleski; Naoko Seki; JON WIGGINTON; Susan E Wilson; Bruce R Blazar; Anatoli Malyguine; Thomas J Sayers; Robert Wiltrout
Synergistic anti-tumor responses after administration of agonistic antibodies to CD40 and IL-2: coordination of dendritic and CD8+ cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2727-33.
2002: Arati Raziuddin; Dan Longo; Michael Bennett; Robin Winkler-Pickett; John R Ortaldo; William Murphy
Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens.
Blood 2002;100(8):3026-33.
2002: Rosalba Salcedo; Manuela Martins-Green; Barry Gertz; Joost J Oppenheim; William Murphy
Combined administration of antibodies to human interleukin 8 and epidermal growth factor receptor results in increased antimetastatic effects on human breast carcinoma xenografts.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(8):2655-65.
2002: Jamie L Szocinski; Annette Khaled; Julie Hixon; Douglas Halverson; Satoshi Funakoshi; William C Fanslow; Ann Boyd; Dennis D Taub; Scott K Durum; Clay B Siegall; Dan Longo; William Murphy
Activation-induced cell death of aggressive histology lymphomas by CD40 stimulation: induction of bax.
Blood 2002;100(1):217-23.
2002: Lisbeth A Welniak; Rui Sun; William Murphy
The role of growth hormone in T-cell development and reconstitution.
Journal of leukocyte biology 2002;71(3):381-7.
2002: Suzanne Kadereit; Linda S Deeds; Stephen E Haynesworth; Omer N Koc; Margaret M Kozik; Emese Szekely; Kathleen Daum-Woods; Glenn W Goetchius; Pingfu Fu; Lisbeth A Welniak; William Murphy; Mary J Laughlin
Expansion of LTC-ICs and maintenance of p21 and BCL-2 expression in cord blood CD34(+)/CD38(-) early progenitors cultured over human MSCs as a feeder layer.
Stem cells (Dayton, Ohio) 2002;20(6):573-82.
2002: Julie A Hixon; Miriam R Anver; Bruce R Blazar; Angela Panoskaltsis-Mortari; Robert Wiltrout; William Murphy
Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(6):316-25.
2002: Crystal Y Koh; Arati Raziuddin; Lisbeth A Welniak; Bruce R Blazar; Michael Bennett; William Murphy
NK inhibitory-receptor blockade for purging of leukemia: effects on hematopoietic reconstitution.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2002;8(1):17-25.
2002: You-Hong Cui; Yingying Le; Wanghua Gong; Paul Proost; Jo Van Damme; William Murphy; Ji Ming Wang
Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(1):434-42.
2001: G P Schneider; Rosalba Salcedo; Lisbeth Welniak; O M Zack Howard; William Murphy
The diverse role of chemokines in tumor progression: prospects for intervention (Review).
International journal of molecular medicine 2001;8(3):235-44.
2001: Rosalba Salcedo; Howard A Young; M L Ponce; J M Ward; Hynda K Kleinman; William Murphy; Joost J Oppenheim
Eotaxin (CCL11) induces in vivo angiogenic responses by human CCR3+ endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7571-8.
2001: William Murphy; Crystal Y Koh; Arati Raziuddin; Michael Bennett; Dan Longo
Immunobiology of natural killer cells and bone marrow transplantation: merging of basic and preclinical studies.
Immunological reviews 2001;181():279-89.
2001: Crystal Y Koh; Bruce R Blazar; T George; Lisbeth A Welniak; C M Capitini; Arati Raziuddin; William Murphy; Michael Bennett
Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo.
Blood 2001;97(10):3132-7.
2001: K Tani; William Murphy; Oleg Chertov; Joost J Oppenheim; Ji Ming Wang
The neutrophil granule protein cathepsin G activates murine T lymphocytes and upregulates antigen-specific IG production in mice.
Biochemical and biophysical research communications 2001;282(4):971-6.
2001: C K Lee ; Kyungjae Kim; Lisbeth Welniak; William Murphy; Kathrin Muegge; Scott K Durum
Thymic emigrants isolated by a new method possess unique phenotypic and functional properties.
Blood 2001;97(5):1360-9.
2001: Lisbeth A Welniak; Annette Khaled; Miriam R Anver; Kristin L Komschlies; Robert Wiltrout; Scott K Durum; F R Ruscetti; B R Blazar; William Murphy
Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):2924-8.
2001: Lisbeth A Welniak; B R Blazar; Robert Wiltrout; Miriam R Anver; William Murphy
Role of interleukin-12 in acute graft-versus-host disease(1).
Transplantation proceedings 2001;33(1-2):1752-3.
2001: William Murphy; Eduardo Eizirik; Warren E Johnson; Y P Zhang; O A Ryder; Stephen J O'Brien
Molecular phylogenetics and the origins of placental mammals.
Nature 2001;409(6820):614-8.
2001: Vassiliki A Boussiotis; Z M Chen; J C Zeller; William Murphy; Alla Berezovskaya; S Narula; M G Roncarolo; B R Blazar
Altered T-cell receptor + CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease.
Blood 2001;97(2):565-71.
2001: Lisbeth Welniak; S M Richards; William Murphy
Effects of prolactin on hematopoiesis.
Lupus 2001;10(10):700-5.
2001: Julie A Hixon; Bruce R Blazar; Miriam R Anver; Robert Wiltrout; William Murphy
Antibodies to CD40 induce a lethal cytokine cascade after syngeneic bone marrow transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001;7(3):136-43.
2000: Angela Panoskaltsis-Mortari; Patricia A Taylor; Jeffrey S Rubin; Aykut Uren; Lisbeth A Welniak; William Murphy; Kate Farrell; David L Lacey; Bruce R Blazar
Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury.
Blood 2000;96(13):4350-6.
2000: Bruce R Blazar; Christopher J Lees; P J Martin; Randolph J Noelle; B Kwon; William Murphy; Patricia A Taylor
Host T cells resist graft-versus-host disease mediated by donor leukocyte infusions.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):4901-9.
2000: Crystal Y Koh; Lisbeth A Welniak; William Murphy
Adoptive cellular immunotherapy: NK cells and bone marrow transplantation.
Histology and histopathology 2000;15(4):1201-10.
2000: William Murphy
Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes.
The Journal of clinical investigation 2000;106(6):745-7.
2000: S M Richards; William Murphy
Use of human prolactin as a therapeutic protein to potentiate immunohematopoietic function.
Journal of neuroimmunology 2000;109(1):56-62.
2000: Lisbeth A Welniak; Zhigang G Tian; Rui Sun; Jonathan Keller; S Richards; Francis W Ruscetti; William Murphy
Effects of growth hormone and prolactin on hematopoiesis.
Leukemia & lymphoma 2000;38(5-6):435-45.
2000: Angela Panoskaltsis-Mortari; R M Strieter; J R Hermanson; Konstantin Fegeding; William Murphy; Kate Farrell; David L Lacey; Bruce R Blazar
Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation.
Blood 2000;96(3):834-9.
2000: Rosalba Salcedo; M L Ponce; Howard A Young; Ken Wasserman; J M Ward; Hynda K Kleinman; Joost J Oppenheim; William Murphy
Human endothelial cells express CCR2 and respond to MCP-1: direct role of MCP-1 in angiogenesis and tumor progression.
Blood 2000;96(1):34-40.
2000: Arati Raziuddin; Michael Bennett; Robin Winkler-Pickett; John R Ortaldo; Dan Longo; William Murphy
Synergistic effects of in vivo depletion of Ly-49A and Ly-49G2 natural killer cell subsets in the rejection of H2(b) bone marrow cell allografts.
Blood 2000;95(12):3840-4.
2000: AB Alexandroff; andrew jackson; T Paterson; J L Haley; J A Ross; Dan Longo; William Murphy; Keith James; D D Taub
Role for CD40-CD40 ligand interactions in the immune response to solid tumours.
Molecular immunology 2000;37(9):515-26.
2000: William Murphy; Dan Longo
Growth hormone as an immunomodulating therapeutic agent.
Immunology today 2000;21(5):211-3.
2000: K Tani; William Murphy; Oleg Chertov; Rosalba Salcedo; C Y Koh; I Utsunomiya; Satoshi Funakoshi; Osamu Asai; S H Herrmann; Ji Ming Wang; Larry W Kwak; Joost J Oppenheim
Defensins act as potent adjuvants that promote cellular and humoral immune responses in mice to a lymphoma idiotype and carrier antigens.
International immunology 2000;12(5):691-700.
2000: Lisbeth A Welniak; B R Blazar; Miriam R Anver; Robert Wiltrout; William Murphy
Opposing roles of interferon-gamma on CD4+ T cell-mediated graft-versus-host disease: effects of conditioning.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2000;6(6):604-12.
2000: J L Ziebold; J Hixon; A Boyd; William Murphy
Differential effects of CD40 stimulation on normal and neoplastic cell growth.
Archivum immunologiae et therapiae experimentalis 2000;48(4):225-33.
1999: William Murphy; B R Blazar
New strategies for preventing graft-versus-host disease.
Current opinion in immunology 1999;11(5):509-15.
1999: J C Zeller; Angela Panoskaltsis-Mortari; William Murphy; F W Ruscetti; S Narula; M G Roncarolo; Bruce R Blazar
Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(7):3684-91.
1999: John R Ortaldo; Anna T Mason; Robin Winkler-Pickett; Arati Raziuddin; William Murphy; Llewellyn H Mason
Ly-49 receptor expression and functional analysis in multiple mouse strains.
Journal of leukocyte biology 1999;66(3):512-20.
1999: Robert A Kirken; RA Erwin; D Taub; William Murphy; Fariba Behbod; L Wang; Federica Pericle; William L Farrar
Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells.
Journal of leukocyte biology 1999;65(6):891-9.
1999: MA Woody; Lisbeth A Welniak; Rui Sun; Zhigang G Tian; M Henry; S Richards; Arati Raziuddin; Dan Longo; William Murphy
Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine.
Experimental hematology 1999;27(5):811-6.
1999: A Hirano; Dan Longo; Dennis D Taub; D K Ferris; L S Young; A G Eliopoulos; A Agathanggelou; N Cullen; J Macartney; William C Fanslow; William Murphy
Inhibition of human breast carcinoma growth by a soluble recombinant human CD40 ligand.
Blood 1999;93(9):2999-3007.
1999: Rosalba Salcedo; Ken Wasserman; Howard A Young; MC Grimm; O M Zack Howard; M R Anver; Hynda K Kleinman; William Murphy; Joost J Oppenheim
Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization induced by stromal-derived factor-1alpha.
The American journal of pathology 1999;154(4):1125-35.
1999: C K Lee; K Kim; Theresa M Geiman; William Murphy; Kathrin Muegge; Scott K Durum
Cloning thymic precursor cells: demonstration that individual pro-T1 cells have dual T-NK potential and individual pro-T2 cells have dual alphabeta-gammadelta T cell potential.
Cellular immunology 1999;191(2):139-44.
1999: William Murphy; Satoshi Funakoshi; William C Fanslow; H C Rager; Dennis D Taub; Dan Longo
CD40 stimulation promotes human secondary immunoglobulin responses in HuPBL-SCID chimeras.
Clinical immunology (Orlando, Fla.) 1999;90(1):22-7.
1999: MA Woody; Lisbeth A Welniak; S Richards; D D Taub; Z Tian; Rui Sun; Dan Longo; William Murphy
Use of neuroendocrine hormones to promote reconstitution after bone marrow transplantation.
Neuroimmunomodulation 1999;6(1-2):69-80.
1998: William Murphy; Lisbeth A Welniak; D D Taub; Robert Wiltrout; Patricia A Taylor; DA Vallera; M Kopf; H Young; Dan Longo; Bruce R Blazar
Differential effects of the absence of interferon-gamma and IL-4 in acute graft-versus-host disease after allogeneic bone marrow transplantation in mice.
The Journal of clinical investigation 1998;102(9):1742-8.
1998: Scott K Durum; C K Lee; Theresa M Geiman; William Murphy; Kathrin Muegge
CD16 cross-linking blocks rearrangement of the TCR beta locus and development of alpha beta T cells and induces development of NK cells from thymic progenitors.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3325-9.
1998: Sally E Spence; Jonathan Keller; Francis W Ruscetti; Christine S McCauslin; John Gooya; Satoshi Funakoshi; Dan Longo; William Murphy
Engraftment of ex vivo expanded and cycling human cord blood hematopoietic progenitor cells in SCID mice.
Experimental hematology 1998;26(6):507-14.
1998: BY Nguyen; M Clerici; D J Venzon; S Bauza; William Murphy; Dan Longo; M Baseler; N Gesundheit; S Broder; G Shearer; Robert Yarchoan
Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients.
AIDS (London, England) 1998;12(8):895-904.
1998: Emmanuel Contassot; William Murphy; Régis Angonin; JJ Pavy; Marcelo de Carvalho Bittencourt; Eric Robinet; CW Reynolds; Jean-Yves Cahn; Patrick Hervé; Pierre Tiberghien
In vivo alloreactive potential of ex vivo-expanded primary T lymphocytes.
Transplantation 1998;65(10):1365-70.
1998: Osamu Asai; Dan Longo; Zhigang G Tian; R L Hornung; Dennis D Taub; Francis W Ruscetti; William Murphy
Suppression of graft-versus-host disease and amplification of graft-versus-tumor effects by activated natural killer cells after allogeneic bone marrow transplantation.
The Journal of clinical investigation 1998;101(9):1835-42.
1998: Zhigang G Tian; MA Woody; Rui Sun; Lisbeth A Welniak; Arati Raziuddin; Satoshi Funakoshi; G Tsarfaty; Dan Longo; William Murphy
Recombinant human growth hormone promotes hematopoietic reconstitution after syngeneic bone marrow transplantation in mice.
Stem cells (Dayton, Ohio) 1998;16(3):193-9.
1998: Arati Raziuddin; Dan Longo; Llewellyn H Mason; John R Ortaldo; Michael Bennett; William Murphy
Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):87-94.
1997: Joost J Oppenheim; William Murphy; O Chertox; V Schirrmacher; J M Wang
Prospects for cytokine and chemokine biotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(12 Pt 2):2682-6.
1997: Satoshi Funakoshi; A Hirano; M Beckwith; Osamu Asai; G Jorgensen; Z Tian; JL Hornick; Peisheng Hu; Leslie A Khawli; Alan L Epstein; Dan Longo; William Murphy
Antitumor effects of nonconjugated murine Lym-2 and human-mouse chimeric CLL-1 monoclonal antibodies against various human lymphoma cell lines in vitro and in vivo.
Blood 1997;90(8):3160-6.
1997: Oleg Chertov; H Ueda; L L Xu; K Tani; William Murphy; J M Wang; O M Zack Howard; Thomas J Sayers; Joost J Oppenheim
Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils.
The Journal of experimental medicine 1997;186(5):739-47.
1997: William Murphy; Dan Longo
The potential role of NK cells in the separation of graft-versus-tumor effects from graft-versus-host disease after allogeneic bone marrow transplantation.
Immunological reviews 1997;157():167-76.
1997: Dennis D Taub; William Murphy; Osamu Asai; Robert G Fenton; G Peltz; M L Key; SM Turcovski-Corrales; Dan Longo
Induction of alloantigen-specific T cell tolerance through the treatment of human T lymphocytes with wortmannin.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(6):2745-55.
1997: Satoshi Funakoshi; Dennis D Taub; M R Anver; Arati Raziuddin; Osamu Asai; V Reddy; H Rager; William C Fanslow; Dan Longo; William Murphy
Immunologic and hematopoietic effects of CD40 stimulation after syngeneic bone marrow transplantation in mice.
The Journal of clinical investigation 1997;99(3):484-91.
1997: D D Taub; M L Key; Dan Longo; William Murphy
Chemokine-induced human lymphocyte infiltration and engraftment in huPBL-SCID mice.
Methods in enzymology 1997;287():265-91.
1997: Satoshi Funakoshi; Dennis D Taub; Osamu Asai; A Hirano; Francis W Ruscetti; Dan Longo; William Murphy
Effects of CD40 stimulation in the prevention of human EBV-lymphomagenesis.
Leukemia & lymphoma 1997;24(3-4):187-99.
1996: A Raziuddin; Dan Longo; L Mason; J R Ortaldo; William Murphy
Ly-49 G2+ NK cells are responsible for mediating the rejection of H-2b bone marrow allografts in mice.
International immunology 1996;8(12):1833-9.
1996: K C Conlon; M R Anver; Dan Longo; John R Ortaldo; William Murphy
Adoptive immunotherapy involving recombinant human M-CSF and R24 anti-melanoma antibody induces human T-cell infiltration into human melanoma xenografts.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(5):317-23.
1996: William Murphy; D D Taub; Dan Longo
The huPBL-SCID mouse as a means to examine human immune function in vivo.
Seminars in immunology 1996;8(4):233-41.
1996: D D Taub; M Anver; J J Oppenheim; Dan Longo; William Murphy
T lymphocyte recruitment by interleukin-8 (IL-8). IL-8-induced degranulation of neutrophils releases potent chemoattractants for human T lymphocytes both in vitro and in vivo.
The Journal of clinical investigation 1996;97(8):1931-41.
1996: Paul Schwarzenberger; S Spence; N Lohrey; T Kmiecik; Dan Longo; William Murphy; Francis W Ruscetti; Jonathan Keller
Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection.
Blood 1996;87(7):2723-31.
1996: William Murphy; Zhigang G Tian; Osamu Asai; Satoshi Funakoshi; P Rotter; M Henry; R M Strieter; Steven Kunkel; Dan Longo; Dennis D Taub
Chemokines and T lymphocyte activation: II. Facilitation of human T cell trafficking in severe combined immunodeficiency mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(6):2104-11.
1996: Dennis D Taub; SM Turcovski-Corrales; M L Key; Dan Longo; William Murphy
Chemokines and T lymphocyte activation: I. Beta chemokines costimulate human T lymphocyte activation in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(6):2095-2103.
1996: Satoshi Funakoshi; Dan Longo; William Murphy
Differential in vitro and in vivo antitumor effects mediated by anti-CD40 and anti-CD20 monoclonal antibodies against human B-cell lymphomas.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1996;19(2):93-101.
1996: D D Taub; Dan Longo; William Murphy
Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice.
Blood 1996;87(4):1423-31.
1996: O Chertov; D F Michiel; Luoling Xu; Ji Ming Wang; K Tani; William Murphy; Dan Longo; D D Taub; Joost J Oppenheim
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils.
The Journal of biological chemistry 1996;271(6):2935-40.
1996: D D Taub; J R Ortaldo; SM Turcovski-Corrales; M L Key; Dan Longo; William Murphy
Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production.
Journal of leukocyte biology 1996;59(1):81-9.
1995: Zhigang G Tian; Dan Longo; Satoshi Funakoshi; Osamu Asai; Douglass K Ferris; M Widmer; William Murphy
In vivo antitumor effects of unconjugated CD30 monoclonal antibodies on human anaplastic large-cell lymphoma xenografts.
Cancer research 1995;55(22):5335-41.
1995: Sally E Spence; Jonathan Keller; Francis W Ruscetti; K T Czarra; John Gooya; S Funakoshi; Dan Longo; William Murphy
Engraftment of SCID mice by human bone marrow hematopoietic cells cultured in vitro: an in vivo model for human gene transfer.
Leukemia 1995;9 Suppl 1():S43-7.
1995: William Murphy; A Raziuddin; L Mason; V Kumar; M Bennett; Dan Longo
NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(6):2911-7.
1995: William Murphy; Satoshi Funakoshi; M Beckwith; S E Rushing; D K Conley; R J Armitage; William C Fanslow; H C Rager; Dennis D Taub; Francis W Ruscetti
Antibodies to CD40 prevent Epstein-Barr virus-mediated human B-cell lymphomagenesis in severe combined immune deficient mice given human peripheral blood lymphocytes.
Blood 1995;86(5):1946-53.
1995: L Xu; Raffaele Badolato; William Murphy; Dan Longo; M Anver; S Hale; Joost J Oppenheim; Ji Ming Wang
A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1184-90.
1995: J M Turley; S Funakoshi; Francis W Ruscetti; J Kasper; William Murphy; Dan Longo; Maria C Birchenall-Roberts
Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1995;6(6):655-63.
1995: D D Taub; P Proost; William Murphy; M Anver; Dan Longo; J van Damme; J J Oppenheim
Monocyte chemotactic protein-1 (MCP-1), -2, and -3 are chemotactic for human T lymphocytes.
The Journal of clinical investigation 1995;95(3):1370-6.
1995: Robert Wiltrout; T A Gregorio; Robert G Fenton; Dan Longo; P Ghosh; William Murphy; Kristin L Komschlies
Cellular and molecular studies in the treatment of murine renal cancer.
Seminars in oncology 1995;22(1):9-16.
1995: Satoshi Funakoshi; M Beckwith; William C Fanslow; Dan Longo; William Murphy
Epstein-Barr virus-induced human B-cell lymphoma arising in HuPBL-SCID chimeric mice: characterization and the role of CD40 stimulation in their treatment and prevention.
Pathobiology : journal of immunopathology, molecular and cellular biology 1995;63(3):133-42.
1995: William Murphy; H Rui; Dan Longo
Effects of growth hormone and prolactin immune development and function.
Life sciences 1995;57(1):1-14.
1994: G Tsarfaty; Dan Longo; William Murphy
Human insulin-like growth factor I exerts hematopoietic growth-promoting effects after in vivo administration.
Experimental hematology 1994;22(13):1273-7.
1994: Pierre Tiberghien; CW Reynolds; J Keller; S Spence; ML Deschaseaux; Jean Marie Certoux; Emmanuel Contassot; William Murphy; R Lyons; Y Chiang
Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?
Blood 1994;84(4):1333-41.
1994: William Murphy; Scott K Durum; M R Anver; Douglass K Ferris; Daniel W McVicar; John O'Shea; S K Ruscetti; M R Smith; Howard A Young; Dan Longo
Induction of T cell differentiation and lymphomagenesis in the thymus of mice with severe combined immune deficiency (SCID).
Journal of immunology (Baltimore, Md. : 1950) 1994;153(3):1004-14.
1994: William Murphy; D D Taub; M Anver; K Conlon; Joost J Oppenheim; David J Kelvin; Dan Longo
Human RANTES induces the migration of human T lymphocytes into the peripheral tissues of mice with severe combined immune deficiency.
European journal of immunology 1994;24(8):1823-7.
1994: D D Taub; G Tsarfaty; A R Lloyd; S K Durum; Dan Longo; William Murphy
Growth hormone promotes human T cell adhesion and migration to both human and murine matrix proteins in vitro and directly promotes xenogeneic engraftment.
The Journal of clinical investigation 1994;94(1):293-300.
1994: Raffaele Badolato; Ji Ming Wang; William Murphy; A R Lloyd; D F Michiel; L L Bausserman; David J Kelvin; Joost J Oppenheim
Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.
The Journal of experimental medicine 1994;180(1):203-9.
1994: Satoshi Funakoshi; Dan Longo; M Beckwith; D K Conley; G Tsarfaty; Ilan Tsarfaty; R J Armitage; William C Fanslow; M K Spriggs; William Murphy
Inhibition of human B-cell lymphoma growth by CD40 stimulation.
Blood 1994;83(10):2787-94.
1993: A K Siefer; Dan Longo; C L Harrison; C W Reynolds; William Murphy
Activated natural killer cells and interleukin-2 promote granulocytic and megakaryocytic reconstitution after syngeneic bone marrow transplantation in mice.
Blood 1993;82(8):2577-84.
1993: William Murphy; T C Back; K C Conlon; Kristin L Komschlies; John R Ortaldo; Thomas J Sayers; Robert Wiltrout; Dan Longo
Antitumor effects of interleukin-7 and adoptive immunotherapy on human colon carcinoma xenografts.
The Journal of clinical investigation 1993;92(4):1918-24.
1993: William Murphy; C W Reynolds; P Tiberghien; Dan Longo
Natural killer cells and bone marrow transplantation.
Journal of the National Cancer Institute 1993;85(18):1475-82.
1993: William Murphy; S K Durum; Dan Longo
Differential effects of growth hormone and prolactin on murine T cell development and function.
The Journal of experimental medicine 1993;178(1):231-6.
1993: William Murphy; K C Conlon; Thomas J Sayers; Robert Wiltrout; T C Back; John R Ortaldo; Dan Longo
Engraftment and activity of anti-CD3-activated human peripheral blood lymphocytes transferred into mice with severe combined immune deficiency.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(8 Pt 1):3634-42.
1992: William Murphy; S K Durum; Dan Longo
Role of neuroendocrine hormones in murine T cell development. Growth hormone exerts thymopoietic effects in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(12):3851-7.
1992: William Murphy; S K Durum; M Anver; M Frazier; Dan Longo
Recombinant human growth hormone promotes human lymphocyte engraftment in immunodeficient mice and results in an increased incidence of human Epstein Barr virus-induced B-cell lymphoma.
Brain, behavior, and immunity 1992;6(4):355-64.
1992: William Murphy; G Tsarfaty; Dan Longo
Growth hormone exerts hematopoietic growth-promoting effects in vivo and partially counteracts the myelosuppressive effects of azidothymidine.
Blood 1992;80(6):1443-7.
1992: William Murphy; Dan Longo
Hematopoietic growth-promoting effects of natural killer cells in mice in response to in vivo administration of human interleukin-2.
Journal of the National Cancer Institute 1992;84(15):1195-200.
1992: William Murphy; Jonathan Keller; C L Harrison; H A Young; Dan Longo
Interleukin-2-activated natural killer cells can support hematopoiesis in vitro and promote marrow engraftment in vivo.
Blood 1992;80(3):670-7.
1992: William Murphy; Scott K Durum; M R Anver; Dan Longo
Immunologic and hematologic effects of neuroendocrine hormones. Studies on DW/J dwarf mice.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(12):3799-805.
1992: William Murphy; M Bennett; M R Anver; M Baseler; Dan Longo
Human-mouse lymphoid chimeras: host-vs.-graft and graft-vs.-host reactions.
European journal of immunology 1992;22(6):1421-7.
1992: William Murphy; S K Durum; Dan Longo
Human growth hormone promotes engraftment of murine or human T cells in severe combined immunodeficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4481-5.
1992: William Murphy; M Bennett; V Kumar; Dan Longo
Donor-type activated natural killer cells promote marrow engraftment and B cell development during allogeneic bone marrow transplantation.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2953-60.
1990: William Murphy; Vinay Kumar; Michael Bennett
Natural killer cells activated with interleukin 2 in vitro can be adoptively transferred and mediate hematopoietic histocompatibility-1 antigen-specific bone marrow rejection in vivo.
European journal of immunology 1990;20(8):1729-34.
1990: William Murphy; Vinay Kumar; J C Cope; Michael Bennett
An absence of T cells in murine bone marrow allografts leads to an increased susceptibility to rejection by natural killer cells and T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3305-11.
1989: William Murphy; V Kumar; M Bennett
Immunobiology of bone marrow transplantation: studies using scid mice.
Current topics in microbiology and immunology 1989;152():251-8.
1987: Michael Bennett; Vinay Kumar; A Mikhael; William Murphy; R M Rembecki; charles sentman; Chella S David
Rejection of bone marrow cells by irradiated mice: NK and T cells recognize different antigens.
Transplantation proceedings 1987;19(6 Suppl 7):5-11.
1987: William Murphy; Vinay Kumar; Michael Bennett
Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized.
The Journal of experimental medicine 1987;166(5):1499-509.
1987: William Murphy; V Kumar; M Bennett
Rejection of bone marrow allografts by mice with severe combined immune deficiency (SCID). Evidence that natural killer cells can mediate the specificity of marrow graft rejection.
The Journal of experimental medicine 1987;165(4):1212-7.
1983: J Battey; C Moulding; R Taub; William Murphy; T Stewart; H Potter; G Lenoir; P Leder
The human c-myc oncogene: structural consequences of translocation into the IgH locus in Burkitt lymphoma.
Cell 1983;34(3):779-87.