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Wolfgang Siess

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Andreas Schober; Wolfgang Siess
Lysophosphatidic acid in atherosclerotic diseases.
Roghieh Djafarzadeh; Pankaj Goyal; Susanne Himmelein; Elfriede Noessner; Susan Notohamiprodjo; Andrea Ribeiro; Matthias Sauter; Wolfgang Siess; Thomas Sitter; Markus Wörnle; Peter J Nelson
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells.
Lisa J Schober; Richard Brandl; Suman Dwivedi; Anna L Khandoga; Takayuki Maruyama; Sandra Penz; Wolfgang Siess
The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood.

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All Publications

2012: Andreas Schober; Wolfgang Siess
Lysophosphatidic acid in atherosclerotic diseases.
British journal of pharmacology 2012;167(3):465-82.
2012: Roghieh Djafarzadeh; Pankaj Goyal; Susanne Himmelein; Elfriede Noessner; Susan Notohamiprodjo; Andrea Ribeiro; Matthias Sauter; Wolfgang Siess; Thomas Sitter; Markus Wörnle; Peter J Nelson
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells.
PloS one 2012;7(4):e33963.
2011: Lisa J Schober; Richard Brandl; Suman Dwivedi; Anna L Khandoga; Takayuki Maruyama; Sandra Penz; Wolfgang Siess
The role of PGE(2) in human atherosclerotic plaque on platelet EP(3) and EP(4) receptor activation and platelet function in whole blood.
Journal of thrombosis and thrombolysis 2011;32(2):158-66.
2011: Anna L Khandoga; Dharmendra Pandey; Ulrich Welsch; Richard Brandl; Wolfgang Siess
GPR92/LPA₅ lysophosphatidate receptor mediates megakaryocytic cell shape change induced by human atherosclerotic plaques.
Cardiovascular research 2011;90(1):157-64.
2011: Pankaj Goyal; Antje Behring; Abhishek Kumar; Wolfgang Siess
STK35L1 associates with nuclear actin and regulates cell cycle and migration of endothelial cells.
PloS one 2011;6(1):e16249.
2010: Suman Dwivedi; Dharmendra Pandey; Anna L Khandoga; Richard Brandl; Wolfgang Siess
Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque.
Journal of translational medicine 2010;8():128.
2010: Sandra Penz; Isabell Bernlochner; Orsolya Tóth; Reinhard Lorenz; Andreas Calatzis; Wolfgang Siess
Selective and rapid monitoring of dual platelet inhibition by aspirin and P2Y12 antagonists by using multiple electrode aggregometry.
Thrombosis journal 2010;8():9.
2009: Dharmendra Pandey; Pankaj Goyal; Suman Dwivedi; Wolfgang Siess
Unraveling a novel Rac1-mediated signaling pathway that regulates cofilin dephosphorylation and secretion in thrombin-stimulated platelets.
Blood 2009;114(2):415-24.
2009: Jesica R Williams; Anna L Khandoga; Pankaj Goyal; James I Fells; Donna H Perygin; Wolfgang Siess; Abby L Parrill; Gabor Tigyi; Yuko Fujiwara
Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation.
The Journal of biological chemistry 2009;284(25):17304-19.
2009: Pankaj Goyal; Antje Behring; Abhishek Kumar; Wolfgang Siess
Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates.
PloS one 2009;4(9):e6981.
2008: A L Khandoga; Y Fujiwara; Pankaj Goyal; Dharmendra Pandey; R Tsukahara; A Bolen; H Guo; N Wilke; J Liu; W J Valentine; G G Durgam; D D Miller; G Jiang; G D Prestwich; Gabor Tigyi; Wolfgang Siess
Lysophosphatidic acid-induced platelet shape change revealed through LPA(1-5) receptor-selective probes and albumin.
Platelets 2008;19(6):415-27.
2008: Christian Schulz; Sandra Penz; Christof Hoffmann; Harald Langer; Angelika Gillitzer; Simon Schneider; Richard Brandl; Stefan Seidl; Steffen Massberg; Bernd Pichler; Elisabeth Kremmer; Konstantinos Stellos; Tanja Schönberger; Wolfgang Siess; Meinrad Gawaz
Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo.
Basic research in cardiology 2008;103(4):356-67.
2008: Vera Krump-Konvalinkova; Ilona Chwalla; Wolfgang Siess
FTY720 inhibits S1P-mediated endothelial healing: relationship to S1P1-receptor surface expression.
Biochemical and biophysical research communications 2008;370(4):603-8.
2007: Navneet K Tyagi; Azad Kumar; Pankaj Goyal; Dharmendra Pandey; Wolfgang Siess; Rolf Kinne
D-Glucose-recognition and phlorizin-binding sites in human sodium/D-glucose cotransporter 1 (hSGLT1): a tryptophan scanning study.
Biochemistry 2007;46(47):13616-28.
2007: Dharmendra Pandey; Pankaj Goyal; Wolfgang Siess
Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation.
Blood cells, molecules & diseases 2007;38(3):269-79.
2007: Azad Kumar; Navneet K Tyagi; Pankaj Goyal; Dharmendra Pandey; Wolfgang Siess; Rolf Kinne
Sodium-independent low-affinity D-glucose transport by human sodium/D-glucose cotransporter 1: critical role of tryptophan 561.
Biochemistry 2007;46(10):2758-66.
2007: Sandra Penz; Armin J Reininger; Orsolya Toth; Hans Deckmyn; Richard Brandl; Wolfgang Siess
Glycoprotein Ibalpha inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques.
Thrombosis and haemostasis 2007;97(3):435-43.
2006: Orsolya Tóth; Andreas Calatzis; Sandra Penz; Hajna Losonczy; Wolfgang Siess
Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood.
Thrombosis and haemostasis 2006;96(6):781-8.
2006: Pankaj Goyal; Dharmendra Pandey; Wolfgang Siess
Phosphorylation-dependent regulation of unique nuclear and nucleolar localization signals of LIM kinase 2 in endothelial cells.
The Journal of biological chemistry 2006;281(35):25223-30.
2006: Dharmendra Pandey; Pankaj Goyal; James R Bamburg; Wolfgang Siess
Regulation of LIM-kinase 1 and cofilin in thrombin-stimulated platelets.
Blood 2006;107(2):575-83.
2006: Wolfgang Siess
Platelet interaction with bioactive lipids formed by mild oxidation of low-density lipoprotein.
Pathophysiology of haemostasis and thrombosis 2006;35(3-4):292-304.
2005: Navneet K Tyagi; Pankaj Goyal; Azad Kumar; Dharmendra Pandey; Wolfgang Siess; Rolf Kinne
High-yield functional expression of human sodium/d-glucose cotransporter1 in Pichia pastoris and characterization of ligand-induced conformational changes as studied by tryptophan fluorescence.
Biochemistry 2005;44(47):15514-24.
2005: Pankaj Goyal; Dharmendra Pandey; Antje Behring; Wolfgang Siess
Inhibition of nuclear import of LIMK2 in endothelial cells by protein kinase C-dependent phosphorylation at Ser-283.
The Journal of biological chemistry 2005;280(30):27569-77.
2005: Gangadhar G Durgam; Tamas Virag; Michelle D Walker; Ryoko Tsukahara; Satoshi Yasuda; Karoly Liliom; Laurens van Meeteren; Wouter H Moolenaar; Nicole Wilke; Wolfgang Siess; Gabor Tigyi; Duane D Miller
Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.
Journal of medicinal chemistry 2005;48(15):4919-30.
2005: Sandra Penz; Armin J Reininger; Richard Brandl; Pankaj Goyal; Tamer Rabie; Isabell Bernlochner; Enno Rother; Christine Goetz; Bernd Engelmann; Peter A Smethurst; Willem H Ouwehand; Richard W Farndale; Bernhard Nieswandt; Wolfgang Siess
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):898-909.
2005: Matthias S Göpfert; Frank Siedler; Wolfgang Siess; Alois Sellmayer
Structural identification of oxidized acyl-phosphatidylcholines that induce platelet activation.
Journal of vascular research 2005;42(2):120-32.
2005: Vera Krump-Konvalinkova; Satoshi Yasuda; Tina Rubic; Natalia Makarova; Jörg Mages; Wolfgang Erl; Claudia A Vosseler; Charles James Kirkpatrick; Gabor Tigyi; Wolfgang Siess
Stable knock-down of the sphingosine 1-phosphate receptor S1P1 influences multiple functions of human endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):546-52.
2004: Wolfgang Siess; Gabor Tigyi
Thrombogenic and atherogenic activities of lysophosphatidic acid.
Journal of cellular biochemistry 2004;92(6):1086-94.
2004: Nadine Haserück; Wolfgang Erl; Dharmendra Pandey; Gabor Tigyi; Philippe Ohlmann; Catherine Ravanat; Christian Gachet; Wolfgang Siess
The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors.
Blood 2004;103(7):2585-92.
2003: G Sandmann; Wolfgang Siess; Markus Essler
Lysophosphatidic acid is the unique platelet-activating substance in human malignant ascites.
European journal of medical research 2003;8(9):397-404.
2003: Enno Rother; Richard Brandl; Daniel L Baker; Pankaj Goyal; Harry Gebhard; Gabor Tigyi; Wolfgang Siess
Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques.
Circulation 2003;108(6):741-7.
2003: Markus Fueller; Dong-An Wang; Gabor Tigyi; Wolfgang Siess
Activation of human monocytic cells by lysophosphatidic acid and sphingosine-1-phosphate.
Cellular signalling 2003;15(4):367-75.
2002: Wolfgang Siess
Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate.
Biochimica et biophysica acta 2002;1582(1-3):204-15.
2001: Wolfgang Erl; Wolfgang Siess
Sphingosine-1-phosphate and the leading Edg-1 of vascular smooth muscle cells.
Circulation research 2001;89(6):474-6.
2001: M Bauer; P Maschberger; L Quek; S J Briddon; D Dash; M Weiss; Steve P Watson; Wolfgang Siess
Genetic and pharmacological analyses of involvement of Src-family, Syk and Btk tyrosine kinases in platelet shape change. Src-kinases mediate integrin alphaIIb beta3 inside-out signalling during shape change.
Thrombosis and haemostasis 2001;85(2):331-40.
2001: Regis BOBE; Jonathan Wilde; P Maschberger; Kanamarlapudi Venkateswarlu; Peter J Cullen; Wolfgang Siess; Steve P Watson
Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation.
Blood 2001;97(3):678-84.
2000: K Bauer; M Kratzer; M Otte; K L de Quintana; J Hagmann; G J Arnold; C Eckerskorn; F Lottspeich; Wolfgang Siess
Human CLP36, a PDZ-domain and LIM-domain protein, binds to alpha-actinin-1 and associates with actin filaments and stress fibers in activated platelets and endothelial cells.
Blood 2000;96(13):4236-45.
2000: Jonathan Wilde; Michaela Retzer; Wolfgang Siess; Steve P Watson
ADP-induced platelet shape change: an investigation of the signalling pathways involved and their dependence on the method of platelet preparation.
Platelets 2000;11(5):286-95.
2000: P Maschberger; M Bauer; J Baumann-Siemons; KJ Zangl; E V Negrescu; Armin J Reininger; Wolfgang Siess
Mildly oxidized low density lipoprotein rapidly stimulates via activation of the lysophosphatidic acid receptor Src family and Syk tyrosine kinases and Ca2+ influx in human platelets.
The Journal of biological chemistry 2000;275(25):19159-66.
2000: Markus Essler; Michaela Retzer; M Bauer; KJ Zangl; Gabor Tigyi; Wolfgang Siess
Stimulation of platelets and endothelial cells by mildly oxidized LDL proceeds through activation of lysophosphatidic acid receptors and the Rho/Rho-kinase pathway. Inhibition by lovastatin.
Annals of the New York Academy of Sciences 2000;905():282-6.
2000: Wolfgang Siess; Markus Essler; Richard Brandl
Lysophosphatidic acid and sphingosine 1-phosphate: two lipid villains provoking cardiovascular diseases?
IUBMB life 2000;49(3):167-71.
2000: Michaela Retzer; Wolfgang Siess; Markus Essler
Mildly oxidised low density lipoprotein induces platelet shape change via Rho-kinase-dependent phosphorylation of myosin light chain and moesin.
FEBS letters 2000;466(1):70-4.
1999: Markus Essler; Michaela Retzer; M Bauer; J W Heemskerk; Martin Aepfelbacher; Wolfgang Siess
Mildly oxidized low density lipoprotein induces contraction of human endothelial cells through activation of Rho/Rho kinase and inhibition of myosin light chain phosphatase.
The Journal of biological chemistry 1999;274(43):30361-4.
1999: M Bauer; Michaela Retzer; Jonathan Wilde; P Maschberger; Markus Essler; Martin Aepfelbacher; Steve P Watson; Wolfgang Siess
Dichotomous regulation of myosin phosphorylation and shape change by Rho-kinase and calcium in intact human platelets.
Blood 1999;94(5):1665-72.
1999: Wolfgang Siess; KJ Zangl; Markus Essler; M Bauer; Richard Brandl; C Corrinth; R Bittman; Gabor Tigyi; Martin Aepfelbacher
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6931-6.
1999: Steffen Massberg; Matthias Sausbier; Peter Klatt; M Bauer; Alexander Pfeifer; Wolfgang Siess; Reinhard Fässler; Peter Ruth; Fritz Krombach; Franz Hofmann
Increased adhesion and aggregation of platelets lacking cyclic guanosine 3',5'-monophosphate kinase I.
The Journal of experimental medicine 1999;189(8):1255-64.
1998: Bernd Engelmann; B Schaipp; P Dobner; Mechthild Stoeckelhuber; C Kögl; Wolfgang Siess; A Hermetter
Platelet agonists enhance the import of phosphatidylethanolamine into human platelets.
The Journal of biological chemistry 1998;273(43):27800-8.
1996: E V Negrescu; Wolfgang Siess
Dissociation of the alphaIIbbeta3-integrin by EGTA stimulates the tyrosine kinase pp72(syk) without inducing platelet activation.
The Journal of biological chemistry 1996;271(43):26547-53.
1995: E V Negrescu; B Grünberg; M A Kratzer; R Lorenz; Wolfgang Siess
Interaction of antiplatelet drugs in vitro: aspirin, iloprost, and the nitric oxide donors SIN-1 and sodium nitroprusside.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 1995;9(4):619-29.
1995: A Weidtmann; R Scheithe; Nina Hrboticky; A Pietsch; R Lorenz; Wolfgang Siess
Mildly oxidized LDL induces platelet aggregation through activation of phospholipase A2.
Arteriosclerosis, thrombosis, and vascular biology 1995;15(8):1131-8.
1995: D Dash; Martin Aepfelbacher; Wolfgang Siess
Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets.
The Journal of biological chemistry 1995;270(29):17321-6.
1995: Christian Weber; E Negrescu; Wolfgang Erl; A Pietsch; Marion Frankenberger; HW Ziegler-Heitbrock; Wolfgang Siess; Peter C Weber
Inhibitors of protein tyrosine kinase suppress TNF-stimulated induction of endothelial cell adhesion molecules.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(1):445-51.
1995: D Dash; Martin Aepfelbacher; Wolfgang Siess
The association of pp125FAK, pp60Src, CDC42Hs and Rap1B with the cytoskeleton of aggregated platelets is a reversible process regulated by calcium.
FEBS letters 1995;363(3):231-4.
1995: B Grünberg; H J Kruse; E V Negrescu; Wolfgang Siess
Platelet rap1B phosphorylation is a sensitive marker for the action of cyclic AMP- and cyclic GMP-increasing platelet inhibitors and vasodilators.
Journal of cardiovascular pharmacology 1995;25(4):545-51.
1995: B Grünberg; E Negrescu; Wolfgang Siess
Synergistic phosphorylation of platelet rap1B by SIN-1 and iloprost.
European journal of pharmacology 1995;288(3):329-33.
1995: E V Negrescu; K L de Quintana; Wolfgang Siess
Platelet shape change induced by thrombin receptor activation. Rapid stimulation of tyrosine phosphorylation of novel protein substrates through an integrin- and Ca(2+)-independent mechanism.
The Journal of biological chemistry 1995;270(3):1057-61.
1995: H J Kruse; C Mayerhofer; Wolfgang Siess; Peter C Weber
Thrombin receptor-activating peptide sensitizes the human endothelial thrombin receptor.
The American journal of physiology 1995;268(1 Pt 1):C36-44.
1995: M A Kratzer; E V Negrescu; A Hirai; Y K Yeo; P Franke; Wolfgang Siess
The Thrombostat system. A useful method to test antiplatelet drugs and diets.
Seminars in thrombosis and hemostasis 1995;21 Suppl 2():25-31.
1994: H J Kruse; B Grünberg; Wolfgang Siess; Peter C Weber
Formation of biologically active autacoids is regulated by calcium influx in endothelial cells.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(11):1821-8.
1994: H Haag; B Grünberg; Christian Weber; F Vauti; Martin Aepfelbacher; Wolfgang Siess
Lovastatin inhibits receptor-stimulated Ca(2+)-influx in retinoic acid differentiated U937 and HL-60 cells.
Cellular signalling 1994;6(7):735-42.
1994: H J Kruse; E V Negrescu; Peter C Weber; Wolfgang Siess
Thrombin-induced Ca2+ influx and protein tyrosine phosphorylation in endothelial cells is inhibited by herbimycin A.
Biochemical and biophysical research communications 1994;202(3):1651-6.
1994: K Luber; Wolfgang Siess
Integrin-dependent protein dephosphorylation on tyrosine induced by activation of the thrombin receptor in human platelets.
Cellular signalling 1994;6(3):279-84.
1993: T Eisenhut; Bhanu Sinha; E Gröttrup-Wolfers; J Semmler; Wolfgang Siess; Stefan Endres
Prostacyclin analogs suppress the synthesis of tumor necrosis factor-alpha in LPS-stimulated human peripheral blood mononuclear cells.
Immunopharmacology 1993;26(3):259-64.
1993: F Vauti; Wolfgang Siess
Simple method of RNA isolation from human leucocytic cell lines.
Nucleic acids research 1993;21(20):4852-3.
1993: B Wilhelm; Wolfgang Siess
Activation of the cloned platelet thrombin receptor decreases the pertussis-toxin-dependent ADP-ribosylation of the membrane and soluble inhibitory guanine-nucleotide-binding-alpha proteins. Inhibition by the prostacyclin analog, iloprost.
European journal of biochemistry / FEBS 1993;216(1):81-8.
1993: Wolfgang Siess; B Grünberg
Phosphorylation of rap1B by protein kinase A is not involved in platelet inhibition by cyclic AMP.
Cellular signalling 1993;5(2):209-14.
1993: Wolfgang Siess; B Grünberg; K Luber
Functional relationship between cyclic AMP-dependent protein phosphorylation and platelet inhibition.
Advances in experimental medicine and biology 1993;344():229-35.
1992: Wolfgang Siess; B Grünberg; K Luber; F Vauti; B Wilhelm
Platelet signal transduction mechanisms induced by eicosanoids.
Eicosanoids 1992;5 Suppl():S13-5.
1991: Wolfgang Siess; B Wilhelm; Martin Aepfelbacher; J M Gennity
Ca2+ ionophore A23187 and thrombin inhibit the pertussis-toxin-induced ADP-ribosylation of the alpha-subunit of the inhibitory guanine-nucleotide-binding protein and other proteins in human platelets.
European journal of biochemistry / FEBS 1991;202(1):145-50.
1991: J M Gennity; Wolfgang Siess
Thrombin inhibits the pertussis-toxin-dependent ADP-ribosylation of a novel soluble Gi-protein in human platelets.
The Biochemical journal 1991;279 ( Pt 3)():643-50.
1990: Wolfgang Siess; E G Lapetina
Functional relationship between cyclic AMP-dependent protein phosphorylation and platelet inhibition.
The Biochemical journal 1990;271(3):815-9.
1990: Wolfgang Siess; Deborah Winegar; E G Lapetina
Rap1-B is phosphorylated by protein kinase A in intact human platelets.
Biochemical and biophysical research communications 1990;170(2):944-50.
1990: Wolfgang Siess
Platelets in the pathogenesis of atherosclerosis.
Advances in experimental medicine and biology 1990;273():119-27.
1989: Wolfgang Siess; E G Lapetina
Platelet aggregation induced by alpha 2-adrenoceptor and protein kinase C activation. A novel synergism.
The Biochemical journal 1989;263(2):377-85.
1989: Wolfgang Siess; E G Lapetina
Prostacyclin inhibits platelet aggregation induced by phorbol ester or Ca2+ ionophore at steps distal to activation of protein kinase C and Ca2+-dependent protein kinases.
The Biochemical journal 1989;258(1):57-65.
1989: C Olbrich; Wolfgang Siess
Epinephrine and the Ca2+ ionophore A23187 synergistically induce platelet aggregation without protein kinase C activation.
FEBS letters 1989;243(2):275-9.
1989: C Olbrich; Martin Aepfelbacher; Wolfgang Siess
Epinephrine potentiates calcium mobilization and activation of protein kinases in platelets stimulated by ADP through a mechanism unrelated to phospholipase C.
Cellular signalling 1989;1(5):483-92.
1989: Wolfgang Siess
Molecular mechanisms of platelet activation.
Physiological reviews 1989;69(1):58-178.
1988: Wolfgang Siess; E G Lapetina
Ca2+ mobilization primes protein kinase C in human platelets. Ca2+ and phorbol esters stimulate platelet aggregation and secretion synergistically through protein kinase C.
The Biochemical journal 1988;255(1):309-18.
1988: Rupert Gerzer; B Karrenbrock; Wolfgang Siess; J M Heim
Direct comparison of the effects of nitroprusside, SIN 1, and various nitrates on platelet aggregation and soluble guanylate cyclase activity.
Thrombosis research 1988;52(1):11-21.
1987: Wolfgang Siess; E G Lapetina
Phorbol esters sensitize platelets to activation by physiological agonists.
Blood 1987;70(5):1373-81.
1987: E G Lapetina; Wolfgang Siess
Measurement of inositol phospholipid turnover in platelets.
Methods in enzymology 1987;141():176-92.
1986: Wolfgang Siess; E G Lapetina
Neomycin inhibits inositol phosphate formation in human platelets stimulated by thrombin but not other agonists.
FEBS letters 1986;207(1):53-7.
1986: Wolfgang Siess
Inositol phospholipid metabolism and platelet function.
Biochemical pharmacology 1986;35(18):3184-7.
1986: Wolfgang Siess; M Stifel; H Binder; P C Weber
Activation of V1-receptors by vasopressin stimulates inositol phospholipid hydrolysis and arachidonate metabolism in human platelets.
The Biochemical journal 1986;233(1):83-91.
1985: H Binder; P C Weber; Wolfgang Siess
Separation of inositol phosphates and glycerophosphoinositol phosphates by high-performance liquid chromatography.
Analytical biochemistry 1985;148(1):220-7.
1985: Wolfgang Siess
Evidence for the formation of inositol 4-monophosphate in stimulated human platelets.
FEBS letters 1985;185(1):151-6.
1985: Wolfgang Siess; B Boehlig; P C Weber; E G Lapetina
Prostaglandin endoperoxide analogues stimulate phospholipase C and protein phosphorylation during platelet shape change.
Blood 1985;65(5):1141-8.
1985: C von Schacky; Wolfgang Siess; S Fischer; P C Weber
A comparative study of eicosapentaenoic acid metabolism by human platelets in vivo and in vitro.
Journal of lipid research 1985;26(4):457-64.
1985: Wolfgang Siess; H Binder
Thrombin induces the rapid formation of inositol bisphosphate and inositol trisphosphate in human platelets.
FEBS letters 1985;180(1):107-12.
1985: E G Lapetina; S P Watson; Wolfgang Siess
Prostaglandin endoperoxide analogues stimulate formation of 1,2-diacylglycerol and myo-inositol 1,4,5-triphosphate in human platelets.
Advances in prostaglandin, thromboxane, and leukotriene research 1985;15():115-7.
1984: Wolfgang Siess; F L Siegel; E G Lapetina
Dihomogammalinolenic acid, but not eicosapentaenoic acid, activates washed human platelets.
Biochimica et biophysica acta 1984;801(2):265-76.
1984: Wolfgang Siess; P C Weber; E G Lapetina
Activation of phospholipase C is dissociated from arachidonate metabolism during platelet shape change induced by thrombin or platelet-activating factor. Epinephrine does not induce phospholipase C activation or platelet shape change.
The Journal of biological chemistry 1984;259(13):8286-92.
1984: S Fischer; C von Schacky; Wolfgang Siess; T Strasser; P C Weber
Uptake, release and metabolism of docosahexaenoic acid (DHA, c22:6 omega 3) in human platelets and neutrophils.
Biochemical and biophysical research communications 1984;120(3):907-18.
1984: C V Schacky; Wolfgang Siess; R Lorenz; P C Weber
[Unsaturated fatty acids, eicosanoids and atherosclerosis].
Der Internist 1984;25(5):268-74.
1984: P C Weber; B Scherer; Wolfgang Siess
Prostaglandins and hypertension.
Advances in experimental medicine and biology 1984;164():269-81.
1983: Wolfgang Siess; F L Siegel; E G Lapetina
Arachidonic acid stimulates the formation of 1,2-diacylglycerol and phosphatidic acid in human platelets. Degree of phospholipase C activation correlates with protein phosphorylation, platelet shape change, serotonin release, and aggregation.
The Journal of biological chemistry 1983;258(18):11236-42.
1983: E G Lapetina; Wolfgang Siess
The role of phospholipase C in platelet responses.
Life sciences 1983;33(11):1011-8.
1983: Wolfgang Siess; E G Lapetina
Properties and distribution of phosphatidylinositol-specific phospholipase C in human and horse platelets.
Biochimica et biophysica acta 1983;752(2):329-38.
1983: Wolfgang Siess; P Cuatrecasas; E G Lapetina
A role for cyclooxygenase products in the formation of phosphatidic acid in stimulated human platelets. Differential mechanisms of action of thrombin and collagen.
The Journal of biological chemistry 1983;258(8):4683-6.
1983: Wolfgang Siess; R Lorenz; P Roth; P C Weber
Effects of propranolol in vitro and in vivo on platelet function and thromboxane formation in normal volunteers.
Agents and actions 1983;13(1):29-34.
1982: Wolfgang Siess; E G Lapetina; P Cuatrecasas
Cytochalasins inhibit arachidonic acid metabolism in thrombin-stimulated platelets.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(24):7709-13.
1982: Wolfgang Siess; R Lorenz; P Roth; P C Weber
Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infusion.
Circulation 1982;66(1):44-8.
1982: P C Weber; Wolfgang Siess; B Scherer; E Held; H Witzgall; R Lorenz
Arachidonic acid metabolites, hypertension and arteriosclerosis.
Klinische Wochenschrift 1982;60(10):479-88.
1982: Wolfgang Siess; F Dray
Very low levels of 6-keto-prostaglandin F1 alpha in human plasma.
The Journal of laboratory and clinical medicine 1982;99(3):388-98.
1982: J Sraer; Wolfgang Siess; L Moulonguet-Doleris; J P Oudinet; F Dray; Raymond Ardaillou
In vitro prostaglandin synthesis by various rat renal preparations.
Biochimica et biophysica acta 1982;710(1):45-52.
1982: B Scherer; S Fischer; Wolfgang Siess; P C Weber
Analysis of 6-keto-prostaglandin F1 alpha in human urine: age-specific differences.
Prostaglandins 1982;23(1):41-52.
1981: J Randon; T Lecompte; Michel Chignard; Wolfgang Siess; G Marlas; F Dray; B Boris Vargaftig
Dissociation of platelet activation from transmethylation of their membrane phospholipids.
Nature 1981;293(5834):660-2.
1981: M M Landgraf-Leurs; A Loy; C Christea; P C Weber; Wolfgang Siess; L L Herberg; Rüdiger Landgraf
Aggregation and thromboxane B2 formation in platelets and vascular prostacyclin production from genetically obese rats.
Prostaglandins 1981;22(4):521-36.
1981: Wolfgang Siess; P Roth; P C Weber
Stimulated platelet aggregation, thromboxane B2 formation and platelet sensitivity to prostacyclin - a critical evaluation.
Thrombosis and haemostasis 1981;45(3):204-7.
1981: R Lorenz; Wolfgang Siess; P C Weber
Effects of very low versus standard dose acetyl salicylic acid, dipyridamole and sulfinpyrazone on platelet function and thromboxane formation in man.
European journal of pharmacology 1981;70(4):511-8.
1981: Wolfgang Siess; F Dray; C Seillan; C Ody; F Russo-Marie
Prostanoid synthesis by vascular slices and cultured vascular cells of piglet aorta.
Biochemical and biophysical research communications 1981;99(2):608-16.
1981: P C Weber; Wolfgang Siess
Interactions of renal prostaglandins with the renin-angiotensin system.
Pharmacology & therapeutics 1981;15(2):321-37.
1981: P C Weber; Wolfgang Siess; R Lorenz; B Scherer
The role of prostaglandins in essential hypertension.
International journal of obesity 1981;5 suppl 1():125-33.
1980: Wolfgang Siess; P Roth; B Scherer; I Kurzmann; B Böhlig; P C Weber
Platelet-membrane fatty acids, platelet aggregation, and thromboxane formation during a mackerel diet.
Lancet 1980;1(8166):441-4.
1980: P C Weber; Wolfgang Siess; B Scherer
Possible significance of renal prostaglandins in essential hypertension.
Clinical and experimental hypertension 1980;2(3-4):741-60.
1980: P C Weber; B Scherer; E Held; Wolfgang Siess
Reduction of renal prostaglandin E formation in essential hypertension.
Advances in prostaglandin and thromboxane research 1980;7():1145-8.
1980: P C Weber; B Scherer; Wolfgang Siess; E Held; J Schnermann
Possible significance of renal prostaglandins for renin release and blood pressure control.
Advances in prostaglandin and thromboxane research 1980;7():1067-77.
1979: P C Weber; B Scherer; E Held; Wolfgang Siess; H Stoffel
Urinary prostaglandins and kallikrein in essential hypertension.
Clinical science (London, England : 1979) 1979;57 Suppl 5():259s-261s.
1979: P C Weber; B Scherer; Wolfgang Siess; E Held; J Schnermann
Formation and action of prostaglandins in the kidney.
Klinische Wochenschrift 1979;57(19):1021-9.
1979: P C Weber; Wolfgang Siess; B Scherer
[Prostaglandins in cardiovascular and renal function. Biochemical, physiological and clinical findings (author's transl)].
Klinische Wochenschrift 1979;57(9):425-44.
1978: H H Lange; E Held; B Scherer; Wolfgang Siess; H Witzgall; P C Weber
[Pathogenetic, pathophysiological and biochemical aspects of essential hypertension (author's transl)].
Herz 1978;3(4):252-60.
1977: B Scherer; Wolfgang Siess; P C Weber
Radioimmunological and biological measurement of prostaglandins in rabbit urine: decrease of PGE2 excretion at high NaCl intake.
Prostaglandins 1977;13(6):1127-39.