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Anatoliy Yashin

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Alexander Kulminski; Svetlana V Ukraintseva; Konstantin G Arbeev; Liubov Arbeeva; Irina Culminskaya; Anatoliy Yashin
Trade-off in the effect of the APOE gene on the ages at onset of cardiocascular disease and cancer across ages, gender, and human generations.
Anatoliy Yashin; Deqing Wu; Konstantin G Arbeev; Kenneth C Land; Eric Stallard; Svetlana V Ukraintseva
How genes influence life span: the biodemography of human survival.
Anatoliy Yashin; Deqing Wu; Konstantin G Arbeev; Svetlana V Ukraintseva
Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.

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2013: Alexander Kulminski; Svetlana V Ukraintseva; Konstantin G Arbeev; Liubov Arbeeva; Irina Culminskaya; Anatoliy Yashin
Trade-off in the effect of the APOE gene on the ages at onset of cardiocascular disease and cancer across ages, gender, and human generations.
Rejuvenation research 2013;16(1):28-34.
2012: Anatoliy Yashin; Deqing Wu; Konstantin G Arbeev; Kenneth C Land; Eric Stallard; Svetlana V Ukraintseva
How genes influence life span: the biodemography of human survival.
Rejuvenation research 2012;15(4):374-80.
2012: Anatoliy Yashin; Deqing Wu; Konstantin G Arbeev; Svetlana V Ukraintseva
Polygenic effects of common single-nucleotide polymorphisms on life span: when association meets causality.
Rejuvenation research 2012;15(4):381-94.
2012: Anatoliy Yashin; Eric Stallard; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Alexander Kulminski; K C Land
The quadratic hazard model for analyzing longitudinal data on aging, health, and the life span.
Physics of life reviews 2012;9(2):177-88; discussion 195-7.
2012: Igor Akushevich; Konstantin G Arbeev; Julia S Kravchenko; Svetlana V Ukraintseva; Galina Veremeyeva; Alexander V Akleyev; Anatoliy Yashin
New stochastic carcinogenesis model with covariates: an approach involving intracellular barrier mechanisms.
Mathematical biosciences 2012;236(1):16-30.
2011: Alexander Kulminski; Konstantin G Arbeev; Kaare Christensen; Richard Mayeux; Anne B Newman; Michael A Province; Evan C Hadley; Winifred Rossi; Thomas T Perls; Irma T Elo; Anatoliy Yashin
Do gender, disability, and morbidity affect aging rate in the LLFS? Application of indices of cumulative deficits.
Mechanisms of ageing and development 2011;132(4):195-201.
2011: Konstantin G Arbeev; Steven C Hunt; Masayuki Kimura; Abraham Aviv; Anatoliy Yashin
Leukocyte telomere length, breast cancer risk in the offspring: the relations with father's age at birth.
Mechanisms of ageing and development 2011;132(4):149-53.
2011: Konstantin G Arbeev; Svetlana V Ukraintseva; Liubov S Arbeeva; Igor Akushevich; Alexander Kulminski; Anatoliy Yashin
Evaluation of genotype-specific survival using joint analysis of genetic and non-genetic subsamples of longitudinal data.
Biogerontology 2011;12(2):157-66.
2011: Konstantin G Arbeev; Svetlana V Ukraintseva; Igor Akushevich; Alexander Kulminski; Liubov S Arbeeva; Lucy Akushevich; Irina V Culminskaya; Anatoliy Yashin
Age trajectories of physiological indices in relation to healthy life course.
Mechanisms of ageing and development 2011;132(3):93-102.
2011: Igor Akushevich; Lucy Akushevich; Konstantin G Arbeev; Julia S Kravchenko; Svetlana V Ukraintseva; Anatoliy Yashin
Cancer Risk and Behavioral Factors, Comorbidities, and Functional Status in the US Elderly Population.
ISRN oncology 2011;2011():415790.
2010: Svetlana V Ukraintseva; Konstantin G Arbeev; Igor Akushevich; Alexander Kulminski; Liubov Arbeeva; Irina Culminskaya; Lucy Akushevich; Anatoliy Yashin
Trade-offs between cancer and other diseases: do they exist and influence longevity?
Rejuvenation research 2010;13(4):387-96.
2010: Anatoliy Yashin; Konstantin G Arbeev; Igor Akushevich; Svetlana V Ukraintseva; Alexander Kulminski; Liubov S Arbeeva; Irina Culminskaya
Exceptional survivors have lower age trajectories of blood glucose: lessons from longitudinal data.
Biogerontology 2010;11(3):257-65.
2010: Alexander Kulminski; Irina Culminskaya; Svetlana V Ukraintseva; Konstantin G Arbeev; Kenneth C Land; Anatoliy Yashin
Beta2-adrenergic receptor gene polymorphisms as systemic determinants of healthy aging in an evolutionary context.
Mechanisms of ageing and development 2010;131(5):338-45.
2010: Anatoliy Yashin; Igor Akushevich; Svetlana V Ukraintseva; Lucy Akushevich; Konstantin G Arbeev; Alexander Kulminski
Trends in survival and recovery from stroke: evidence from the National Long-Term Care Survey/Medicare data.
Stroke; a journal of cerebral circulation 2010;41(3):563-5.
2010: Alexander Kulminski; Irina V Culminskaya; Svetlana V Ukraintseva; Konstantin G Arbeev; Igor Akushevich; Kenneth C Land; Anatoliy Yashin
Polymorphisms in the ACE and ADRB2 genes and risks of aging-associated phenotypes: the case of myocardial infarction.
Rejuvenation research 2010;13(1):13-21.
2010: A Wienke; S Ripatti; J Palmgren; Anatoliy Yashin
A bivariate survival model with compound Poisson frailty.
Statistics in medicine 2010;29(2):275-83.
2010: Anatoliy Yashin; Konstantin G Arbeev; Igor Akushevich; Liubov Arbeeva; Julia Kravchenko; Dora Il'yasova; Alexander Kulminski; Lucy Akushevich; Irina Culminskaya; Deqing Wu; Svetlana V Ukraintseva
Dynamic determinants of longevity and exceptional health.
Current gerontology and geriatrics research 2010;():.
2009: Alexander Kulminski; Freerk Molleman; Irina V Culminskaya; Konstantin G Arbeev; Svetlana V Ukraintseva; James R Carey; Anatoliy Yashin
Date of eclosion modulates longevity: insights across dietary-restriction gradients and female reproduction in the mexfly Anastrepha ludens.
Experimental gerontology 2009;44(11):718-26.
2009: Anatoliy Yashin; Svetlana V Ukraintseva; Konstantin G Arbeev; Igor Akushevich; Liubov S Arbeeva; Alexander Kulminski
Maintaining physiological state for exceptional survival: What is the normal level of blood glucose and does it change with age?
Mechanisms of ageing and development 2009;130(9):611-8.
2009: Deqing Wu; James R Cypser; Anatoliy Yashin; Thomas Johnson
Multiple mild heat-shocks decrease the Gompertz component of mortality in Caenorhabditis elegans.
Experimental gerontology 2009;44(9):607-12.
2009: Konstantin G Arbeev; Igor Akushevich; Alexander Kulminski; Liubov S Arbeeva; Lucy Akushevich; Svetlana V Ukraintseva; Irina V Culminskaya; Anatoliy Yashin
Genetic model for longitudinal studies of aging, health, and longevity and its potential application to incomplete data.
Journal of theoretical biology 2009;258(1):103-11.
2009: Igor Sidorov; Masayuki Kimura; Anatoliy Yashin; Abraham Aviv
Leukocyte telomere dynamics and human hematopoietic stem cell kinetics during somatic growth.
Experimental hematology 2009;37(4):514-24.
2009: Anatoliy Yashin; Igor Akushevich; Konstantin G Arbeev; Lucy Akushevich; Alexander Kulminski; Svetlana V Ukraintseva
Studying health histories of cancer: a new model connecting cancer incidence and survival.
Mathematical biosciences 2009;218(2):88-97.
2009: Alexander Kulminski; Konstantin G Arbeev; Irina V Culminskaya; Svetlana V Ukraintseva; Kaare Christensen; Anatoliy Yashin
Health-related phenotypes and longevity in danish twins.
The journals of gerontology. Series A, Biological sciences and medical sciences 2009;64(1):1-8.
2009: Anatoliy Yashin; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Alexander Kulminski; Lucy Akushevich
Trade-off between cancer and aging: what role do other diseases play? Evidence from experimental and human population studies.
Mechanisms of ageing and development 2009;130(1-2):98-104.
2008: Alexander Kulminski; Irina V Culminskaya; Svetlana V Ukraintseva; Konstantin G Arbeev; Kenneth C Land; Anatoliy Yashin
Sex-specific health deterioration and mortality: the morbidity-mortality paradox over age and time.
Experimental gerontology 2008;43(12):1052-7.
2008: Alexander Kulminski; Svetlana V Ukraintseva; Irina V Culminskaya; Konstantin G Arbeev; Kenneth C Land; Lucy Akushevich; Anatoliy Yashin
Cumulative deficits and physiological indices as predictors of mortality and long life.
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(10):1053-9.
2008: Alexander M Kulminski; Konstantin G Arbeev; Svetlana V Ukraintseva; Irina V Culminskaya; Kenneth Land; Anatoliy Yashin
Changes in health status among participants of the Framingham Heart Study from the 1960s to the 1990s: application of an index of cumulative deficits.
Annals of epidemiology 2008;18(9):696-701.
2008: Deqing Wu; James R Cypser; Anatoliy Yashin; Thomas Johnson
The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality?
The journals of gerontology. Series A, Biological sciences and medical sciences 2008;63(7):660-8.
2008: Alexander Kulminski; Svetlana V Ukraintseva; Irina V Kulminskaya; Konstantin G Arbeev; Kenneth C Land; Anatoliy Yashin
Cumulative deficits better characterize susceptibility to death in elderly people than phenotypic frailty: lessons from the Cardiovascular Health Study.
Journal of the American Geriatrics Society 2008;56(5):898-903.
2008: Alexander Kulminski; Svetlana V Ukraintseva; Konstantin G Arbeev; Kenneth G Manton; Oshima Junko; George M Martin; Anatoliy Yashin
Association between APOE epsilon 2/epsilon 3/epsilon 4 polymorphism and disability severity in a national long-term care survey sample.
Age and ageing 2008;37(3):288-93.
2008: Anatoliy Yashin; Konstantin G Arbeev; Alexander Kulminski; Igor Akushevich; Lucy Akushevich; Svetlana V Ukraintseva
What age trajectories of cumulative deficits and medical costs tell us about individual aging and mortality risk: Findings from the NLTCS-Medicare data.
Mechanisms of ageing and development 2008;129(4):191-200.
2008: Alexander Kulminski; Svetlana V Ukraintseva; Konstantin G Arbeev; Kenneth G Manton; Oshima Junko; George M Martin; Dora Il'yasova; Anatoliy Yashin
Health-protective and adverse effects of the apolipoprotein E epsilon2 allele in older men.
Journal of the American Geriatrics Society 2008;56(3):478-83.
2008: Alexander Kulminski; Irina V Kulminskaya; Svetlana V Ukraintseva; Kenneth C Land; Anatoliy Yashin
An inverse association between self-reported arthritis and mortality in the elderly: findings from the national long-term care survey.
Rejuvenation research 2008;11(1):251-7.
2008: Anatoliy Yashin; Konstantin G Arbeev; Igor Akushevich; Alexander Kulminski; Lucy Akushevich; Svetlana V Ukraintseva
Model of hidden heterogeneity in longitudinal data.
Theoretical population biology 2008;73(1):1-10.
2008: Svetlana V Ukraintseva; Konstantin G Arbeev; Anatoliy Yashin
Epidemiology of hormone-associated cancers as a reflection of age.
Advances in experimental medicine and biology 2008;630():57-71.
2008: Alexander Kulminski; Konstantin G Arbeev; Irina V Kulminskaya; Svetlana V Ukraintseva; Kenneth C Land; Igor Akushevich; Anatoliy Yashin
Body mass index and nine-year mortality in disabled and nondisabled older U.S. individuals.
Journal of the American Geriatrics Society 2008;56(1):105-10.
2007: Alexander V Khalyavkin; Anatoliy Yashin
Nonpathological senescence arises from unsuitable external influences.
Annals of the New York Academy of Sciences 2007;1119():306-9.
2007: Alexander Kulminski; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Kenneth C Land; Anatoliy Yashin
Accelerated accumulation of health deficits as a characteristic of aging.
Experimental gerontology 2007;42(10):963-70.
2007: Isabella Locatelli; Alessandro Rosina; Paul Lichtenstein; Anatoliy Yashin
A correlated frailty model with long-term survivors for estimating the heritability of breast cancer.
Statistics in medicine 2007;26(20):3722-34.
2007: Alexander Kulminski; Svetlana V Ukraintseva; Anatoliy Yashin
The apolipoprotein E epsilon2 allele and aging-associated health deterioration in older males.
Journal of the American Geriatrics Society 2007;55(9):1479-80.
2007: Anatoliy Yashin; Konstantin G Arbeev; Igor Akushevich; Alexander Kulminski; Lucy Akushevich; Svetlana V Ukraintseva
Stochastic model for analysis of longitudinal data on aging and mortality.
Mathematical biosciences 2007;208(2):538-51.
2007: Alexander Kulminski; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Anatoliy Yashin
Cumulative index of health deficiencies as a characteristic of long life.
Journal of the American Geriatrics Society 2007;55(6):935-40.
2007: Anatoliy Yashin; Konstantin G Arbeev; Alexander Kulminski; Igor Akushevich; Lucy Akushevich; Svetlana V Ukraintseva
Health decline, aging and mortality: how are they related?
Biogerontology 2007;8(3):291-302.
2007: Anatoliy Yashin; Konstantin G Arbeev; Svetlana V Ukraintseva
The accuracy of statistical estimates in genetic studies of aging can be significantly improved.
Biogerontology 2007;8(3):243-55.
2007: Anatoliy Yashin; Konstantin G Arbeev; Alexander Kulminski; Igor Akushevich; Lucy Akushevich; Svetlana V Ukraintseva
Cumulative index of elderly disorders and its dynamic contribution to mortality and longevity.
Rejuvenation research 2007;10(1):75-86.
2007: Alexander Kulminski; Anatoliy Yashin; Konstantin G Arbeev; Igor Akushevich; Svetlana V Ukraintseva; Kenneth C Land; Kenneth G Manton
Cumulative index of health disorders as an indicator of aging-associated processes in the elderly: results from analyses of the National Long Term Care Survey.
Mechanisms of ageing and development 2007;128(3):250-8.
2006: Igor Akushevich; Kenneth G Manton; Alexander Kulminski; M Kovtun; Julia S Kravchenko; Anatoliy Yashin
Population models for the health effects of ionizing radiation.
Radiatsionnaia biologiia, radioecologiia / Rossiĭskaia akademiia nauk 2006;46(6):663-74.
2006: Alexander Kulminski; Anatoliy Yashin; Svetlana V Ukraintseva; Igor Akushevich; Konstantin G Arbeev; Kenneth C Land; Kenneth G Manton
Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.
Mechanisms of ageing and development 2006;127(11):840-8.
2006: Michael Golubovsky; Nataly Y Weisman; Konstantin G Arbeev; Svetlana V Ukraintseva; Anatoliy Yashin
Decrease in the lgl tumor suppressor dose in Drosophila increases survival and longevity in stress conditions.
Experimental gerontology 2006;41(9):819-27.
2006: Alexander V Khalyavkin; Anatoliy Yashin
Inadequate intensity of various components of total environmental signals can lead to natural aging.
Annals of the New York Academy of Sciences 2006;1067():45-6.
2006: Svetlana V Ukraintseva; Frank A Sloan; Konstantin G Arbeev; Anatoliy Yashin
Increasing rates of dementia at time of declining mortality from stroke.
Stroke; a journal of cerebral circulation 2006;37(5):1155-9.
2006: Deqing Wu; Shane L Rea; Anatoliy Yashin; Thomas Johnson
Visualizing hidden heterogeneity in isogenic populations of C. elegans.
Experimental gerontology 2006;41(3):261-70.
2005: Vladimir N Anisimov; Lev M Berstein; Irina G Popovich; Mark A Zabezhinski; Peter A Egormin; Margarita L Tyndyk; Ivan V Anikin; Anna V Semenchenko; Anatoliy Yashin
Central and peripheral effects of insulin/IGF-1 signaling in aging and cancer: antidiabetic drugs as geroprotectors and anticarcinogens.
Annals of the New York Academy of Sciences 2005;1057():220-34.
2005: Andreas Wienke; Konstantin G Arbeev; Isabella Locatelli; Anatoliy Yashin
A comparison of different bivariate correlated frailty models and estimation strategies.
Mathematical biosciences 2005;198(1):1-13.
2005: Vladimir N Anisimov; Svetlana V Ukraintseva; Anatoliy Yashin
Cancer in rodents: does it tell us about cancer in humans?
Nature reviews. Cancer 2005;5(10):807-19.
2005: Vassily Novoseltsev; Robert Arking; James R Carey; Janna A Novoseltseva; Anatoliy Yashin
Individual fecundity and senescence in Drosophila and medfly.
The journals of gerontology. Series A, Biological sciences and medical sciences 2005;60(8):953-62.
2005: Irina G Popovich; Mark A Zabezhinski; Peter A Egormin; Margarita L Tyndyk; Ivan V Anikin; Alexander A Spasov; Anna V Semenchenko; Anatoliy Yashin; Vladimir N Anisimov
Insulin in aging and cancer: antidiabetic drug Diabenol as geroprotector and anticarcinogen.
The international journal of biochemistry & cell biology 2005;37(5):1117-29.
2005: Armand M Leroi; Andrzej Bartke; Giovanna De Benedictis; Claudio Franceschi; Anton Gartner; Efstathios S Gonos; Eleftherios Gonos; Martin E Fedei; Martin E Feder; Toomas Kivisild; Sylvia Lee; Nesrin Kartaf-Ozer; Nesrin Kartal-Ozer; Michael Schumacher; Ewa Sikora; Eline Slagboom; Mark Tatar; Anatoliy Yashin; Jan Vijg; Bas Zwaan
What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?
Mechanisms of ageing and development 2005;126(3):421-9.
2005: Andreas Wienke; Anne Maria Herskind; Kaare Christensen; Axel Skytthe; Anatoliy Yashin
The heritability of CHD mortality in danish twins after controlling for smoking and BMI.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2005;8(1):53-9.
2005: Alexander Z Begun; Anatoliy Yashin
Genetic markers data in survival studies of twins: the results of a simulation study.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2005;8(1):34-8.
2005: Qihua Tan; Lene Christiansen; Lise Bathum; Jing Hua Zhao; Anatoliy Yashin; James W Vaupel; Kaare Christensen; Torben A Kruse
Estimating haplotype relative risks on human survival in population-based association studies.
Human heredity 2005;59(2):88-97.
2005: Svetlana V Ukraintseva; Anatoliy Yashin
Treating cancer with embryonic stem cells: rationale comes from aging studies.
Frontiers in bioscience : a journal and virtual library 2005;10():588-95.
2004: Slobodan Zdravkovic; Andreas Wienke; Nancy L Pedersen; Marjorie E Marenberg; Anatoliy Yashin; Ulf de Faire
Genetic influences on CHD-death and the impact of known risk factors: comparison of two frailty models.
Behavior genetics 2004;34(6):585-92.
2004: Ganna V Semenchenko; Vladimir N Anisimov; Anatoliy Yashin
Stressors and antistressors: how do they influence life span in HER-2/neu transgenic mice?
Experimental gerontology 2004;39(10):1499-511.
2004: Vladimir N Anisimov; Dmitri A Baturin; Irina G Popovich; Mark A Zabezhinski; Kenneth G Manton; Anna V Semenchenko; Anatoliy Yashin
Effect of exposure to light-at-night on life span and spontaneous carcinogenesis in female CBA mice.
International journal of cancer. Journal international du cancer 2004;111(4):475-9.
2004: A A Romaniukha; J R Carey; Arseniy Karkach; Anatoliy Yashin
[A model of resource reallocation during physiological adaptation in Mediterranean fruit fly females].
Biofizika 2004;49(5):897-903.
2004: Alexei Romanyukha; J R Carey; Arseniy Karkach; Anatoliy Yashin
The impact of diet switching on resource allocation to reproduction and longevity in Mediterranean fruitflies.
Proceedings. Biological sciences / The Royal Society 2004;271(1545):1319-24.
2004: Vassily Novoseltsev; Robert Arking; J R Carey; Janna A Novoseltseva; Anatoliy Yashin
How an individual fecundity pattern looks in Drosophila and medflies.
Annals of the New York Academy of Sciences 2004;1019():577-80.
2004: Svetlana V Ukraintseva; Konstantin G Arbeev; Anatoly I Michalsky; Anatoliy Yashin
Antiaging treatments have been legally prescribed for approximately thirty years.
Annals of the New York Academy of Sciences 2004;1019():64-9.
2004: Vladimir N Anisimov; Konstantin G Arbeev; Irina G Popovich; Mark A Zabezhinksi; Lyubov S Arbeeva; Anatoliy Yashin
Is early life body weight a predictor of longevity and tumor risk in rats?
Experimental gerontology 2004;39(5):807-16.
2004: Isabella Locatelli; Paul Lichtenstein; Anatoliy Yashin
The heritability of breast cancer: a Bayesian correlated frailty model applied to Swedish twins data.
Twin research : the official journal of the International Society for Twin Studies 2004;7(2):182-91.
2004: Vladimir N Anisimov; Konstantin G Arbeev; Irina G Popovich; Mark A Zabezhinksi; Svetlana V Rosenfeld; Tatiana S Piskunova; Lyubov S Arbeeva; Anna V Semenchenko; Anatoliy Yashin
Body weight is not always a good predictor of longevity in mice.
Experimental gerontology 2004;39(3):305-19.
2004: Konstantin G Arbeev; Alexander A Butov; Kenneth G Manton; Igor A Sannikov; Anatoliy Yashin
Disability trends in gender and race groups of early retirement ages in the USA.
Sozial- und Präventivmedizin 2004;49(2):142-51.
2004: Ganna V Semenchenko; Aziz A Khazaeli; James W Curtsinger; Anatoliy Yashin
Stress resistance declines with age: analysis of data from a survival experiment with Drosophila melanogaster.
Biogerontology 2004;5(1):17-30.
2004: Qihua Tan; Giovanna De Benedictis; Anatoliy Yashin; Lise Bathum; Lene Christiansen; Jesper Dahlgaard; N Frizner; W Vach; James W Vaupel; Kaare Christensen; Torben A Kruse
Assessing genetic association with human survival at multi-allelic loci.
Biogerontology 2004;5(2):89-97.
2004: Vassily Novoseltsev; R J Carey; Janna A Novoseltseva; Nikos Papadopoulos; S Blay; Anatoliy Yashin
Systemic mechanisms of individual reproductive life history in female Medflies.
Mechanisms of ageing and development 2004;125(1):77-87.
2003: Andreas Wienke; Niels V Holm; Kaare Christensen; Axel Skytthe; James W Vaupel; Anatoliy Yashin
The heritability of cause-specific mortality: a correlated gamma-frailty model applied to mortality due to respiratory diseases in Danish twins born 1870-1930.
Statistics in medicine 2003;22(24):3873-87.
2003: Irina G Popovich; MA Zabezhinskii; Vladimir N Anisimov; AL Kovalenko; A Yu Petrov; Anna V Semenchenko; Anatoliy Yashin
Effect of neuronol on lifespan and development of spontaneous tumors in SAMP-1 mice with genetically accelerated aging.
Bulletin of experimental biology and medicine 2003;136(6):595-8.
2003: Svetlana V Ukraintseva; Anatoliy Yashin
Opposite phenotypes of cancer and aging arise from alternative regulation of common signaling pathways.
Annals of the New York Academy of Sciences 2003;1010():489-92.
2003: Andreas Wienke; Paul Lichtenstein; Anatoliy Yashin
A bivariate frailty model with a cure fraction for modeling familial correlations in diseases.
Biometrics 2003;59(4):1178-83; discussion 1184-5.
2003: Qihua Tan; Lise Bathum; Lene Christiansen; Giovanna De Benedictis; Jesper Dahlgaard; N Frizner; W Vach; James W Vaupel; Anatoliy Yashin; Kaare Christensen; Torben A Kruse
Logistic regression models for polymorphic and antagonistic pleiotropic gene action on human aging and longevity.
Annals of human genetics 2003;67(Pt 6):598-607.
2003: Giuseppina Rose; Serena Dato; Katia Altomare; Dina Bellizzi; Sabrina Garasto; Valentina Greco; Giuseppe Passarino; Emidio Feraco; Vincenzo Mari; Cristiana Barbi; Massimiliano Bonafe; Claudio Franceschi; Q Tan; Serge I Boiko; Anatoliy Yashin; Giovanna De Benedictis
Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly.
Experimental gerontology 2003;38(10):1065-70.
2003: Vassily Novoseltsev; Janna A Novoseltseva; Sergei I Boyko; Anatoliy Yashin
What fecundity patterns indicate about aging and longevity: insights from Drosophila studies.
The journals of gerontology. Series A, Biological sciences and medical sciences 2003;58(6):484-94.
2003: Irina G Popovich; Boris O Voitenkov; Vladimir N Anisimov; Vadim T Ivanov; Inessa I Mikhaleva; Mark A Zabezhinski; Irina N Alimova; Dmitri A Baturin; Natalia Yu Zavarzina; Svetlana V Rosenfeld; Anna V Semenchenko; Anatoliy Yashin
Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice.
Mechanisms of ageing and development 2003;124(6):721-31.
2003: Vassily Novoseltsev; Janna A Novoseltseva; Anatoliy Yashin
What does a fly's individual fecundity pattern look like? The dynamics of resource allocation in reproduction and ageing.
Mechanisms of ageing and development 2003;124(5):605-17.
2003: Vladimir N Anisimov; Irina G Popovich; Irina N Alimova; Mark A Zabezhinski; Anna V Semenchenko; Anatoliy Yashin
Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice.
Cancer letters 2003;193(1):49-55.
2003: Alexei Romanyukha; Anatoliy Yashin
Age related changes in population of peripheral T cells: towards a model of immunosenescence.
Mechanisms of ageing and development 2003;124(4):433-43.
2003: Vladimir N Anisimov; Irina N Alimova; Dmitri A Baturin; Irina G Popovich; Mark A Zabezhinski; Svetlana V Rosenfeld; Kenneth G Manton; Anna V Semenchenko; Anatoliy Yashin
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
Experimental gerontology 2003;38(4):449-61.
2003: Vladimir N Anisimov; Irina N Alimova; Dmitri A Baturin; Irina G Popovich; Mark A Zabezhinski; Kenneth G Manton; Anna V Semenchenko; Anatoliy Yashin
The effect of melatonin treatment regimen on mammary adenocarcinoma development in HER-2/neu transgenic mice.
International journal of cancer. Journal international du cancer 2003;103(3):300-5.
2003: Alexander V Khalyavkin; Anatoliy Yashin
How the analysis of genetic mutations can help us to solve basic problems in gerontology? II. Life extending genetic modifications in budding yeast S. cereviseae, fruit fly D. melanogaster and laboratory mice M. musculus.
Advances in gerontology = Uspekhi gerontologii / Rossiĭskai͡a akademii͡a nauk, Gerontologicheskoe obshchestvo 2003;12():46-56.
2003: Alexander A Butov; James R Carey; Maxim A Volkov; Mary Sehl; Anatoliy Yashin
Reproduction and survival in Mediterranean fruit flies: a "protein and energy" free radical model of aging.
Biogerontology 2003;4(6):387-95.
2003: Vladimir N Anisimov; Anna V Semenchenko; Anatoliy Yashin
Insulin and longevity: antidiabetic biguanides as geroprotectors.
Biogerontology 2003;4(5):297-307.
2003: Vladimir N Anisimov; Vladimir Kh Khavinson; Irina G Popovich; Mark A Zabezhinski; Irina N Alimova; Svetlana V Rosenfeld; Natalia Yu Zavarzina; Anna V Semenchenko; Anatoliy Yashin
Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice.
Biogerontology 2003;4(4):193-202.
2003: Alexander V Khalyavkin; Anatoliy Yashin
How the analysis of genetic mutations can help us to solve basic problems in gerontology? I. Life extending genetic modifications in round worm C. elegans.
Advances in gerontology = Uspekhi gerontologii / Rossiĭskai͡a akademii͡a nauk, Gerontologicheskoe obshchestvo 2003;11():34-42.
2002: Giuseppe Passarino; C Calignano; A Vallone; C Franceschi; Bernard Jeune; Jean-Marie Robine; Anatoliy Yashin; L Luca Cavalli-Sforza; Giovanna De Benedictis
Male/female ratio in centenarians: a possible role played by population genetic structure.
Experimental gerontology 2002;37(10-11):1283-9.
2002: Nicole Giard; Paul Lichtenstein; Anatoliy Yashin
A multistate model for the genetic analysis of the ageing process.
Statistics in medicine 2002;21(17):2511-26.
2002: Anatoliy Yashin; Svetlana V Ukraintseva; Serge I Boiko; Konstantin G Arbeev
Individual aging and mortality rate: how are they related?
Social biology 2002;49(3-4):206-17.
2002: Slobodan Zdravkovic; A Wienke; N L Pedersen; Marjorie E Marenberg; Anatoliy Yashin; Ulf de Faire
Heritability of death from coronary heart disease: a 36-year follow-up of 20 966 Swedish twins.
Journal of internal medicine 2002;252(3):247-54.
2002: Vladimir N Anisimov; Vladimir Kh Khavinson; Irina N Alimova; A V Semchenko; Anatoliy Yashin
Epithalon decelerates aging and suppresses development of breast adenocarcinomas in transgenic her-2/neu mice.
Bulletin of experimental biology and medicine 2002;134(2):187-90.
2002: Qihua Tan; Dina Bellizzi; G Rose; Sabrina Garasto; Claudio Franceschi; T Kruse; James W Vaupel; Giovanna De Benedictis; Anatoliy Yashin
The influences on human longevity by HUMTHO1.STR polymorphism (Tyrosine Hydroxylase gene). A relative risk approach.
Mechanisms of ageing and development 2002;123(10):1403-10.
2002: Vassily Novoseltsev; Robert Arking; Janna A Novoseltseva; Anatoliy Yashin
Evolutionary optimality applied to Drosophila experiments: hypothesis of constrained reproductive efficiency.
Evolution; international journal of organic evolution 2002;56(6):1136-49.
2002: Qihua Tan; Anatoliy Yashin; Else Marie Bladbjerg; Moniek P M de Maat; Karen Andersen-Ranberg; Bernard Jeune; Kaare Christensen; James W Vaupel
A case-only approach for assessing gene by sex interaction in human longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences 2002;57(4):B129-33.
2002: Anatoliy Yashin; Alexander S Begun; Serge I Boiko; Svetlana V Ukraintseva; Jim Oeppen
New age patterns of survival improvement in Sweden: do they characterize changes in individual aging?
Mechanisms of ageing and development 2002;123(6):637-47.
2002: Massimiliano Bonafè; Cristiana Barbi; Fabiola Olivieri; Anatoliy Yashin; Kirill F Andreev; James W Vaupel; Giovanna De Benedictis; Giuseppina Rose; Giuseppina Carrieri; S Michal Jazwinski; Claudio Franceschi
An allele of HRAS1 3'variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity.
Gene 2002;286(1):121-6.
2002: Anatoliy Yashin; James W Cypser; Thomas Johnson; Anatoli I Michalski; Sergei I Boyko; Vassily Novoseltsev
Heat shock changes the heterogeneity distribution in populations of Caenorhabditis elegans: does it tell us anything about the biological mechanism of stress response?
The journals of gerontology. Series A, Biological sciences and medical sciences 2002;57(3):B83-92.
2002: Qihua Tan; Giovanna De Benedictis; Svetlana V Ukraintseva; Claudio Franceschi; James W Vaupel; Anatoliy Yashin
A centenarian-only approach for assessing gene-gene interaction in human longevity.
European journal of human genetics : EJHG 2002;10(2):119-24.
2002: Alexander A Butov; Maxim A Volkov; Vladimir N Anisimov; Mary Sehl; Anatoliy Yashin
A model of accelerated aging induced by 5-bromodeoxyuridine.
Biogerontology 2002;3(3):175-82.
2002: Anatoli I Michalski; Anatoliy Yashin
Detection of hormesis effect in longevity: simulation approach for heterogeneous population.
Mathematical biosciences 2002;175(1):57-66.
2001: Qihua Tan; Anatoliy Yashin; Giovanna De Benedictis; F Cintolesi; Giuseppina Rose; Massimiliano Bonafe; Claudio Franceschi; W Vach; James W Vaupel
A logistic regression model for measuring gene-longevity associations.
Clinical genetics 2001;60(6):463-9.
2001: Anatoliy Yashin; Alexander S Begun; Serge I Boiko; Svetlana V Ukraintseva; Jim Oeppen
The new trends in survival improvement require a revision of traditional gerontological concepts.
Experimental gerontology 2001;37(1):157-67.
2001: A Butov; T Johnson; J Cypser; I Sannikov; M Volkov; M Sehl; Anatoliy Yashin
Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: the model of balance between cell damage and HSP levels.
Experimental gerontology 2001;37(1):57-66.
2001: Kaare Christensen; Andreas Wienke; Axel Skytthe; Niels V Holm; James W Vaupel; Anatoliy Yashin
Cardiovascular mortality in twins and the fetal origins hypothesis.
Twin research : the official journal of the International Society for Twin Studies 2001;4(5):344-9.
2001: Anatoliy Yashin; Svetlana V Ukraintseva; Giovanna De Benedictis; Vladimir N Anisimov; Alexander A Butov; Konstantin G Arbeev; Dmitri A Jdanov; Serge I Boiko; Alexander S Begun; Massimiliano Bonafe; Claudio Franceschi
Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival.
The journals of gerontology. Series A, Biological sciences and medical sciences 2001;56(10):B432-42.
2001: Anatoliy Yashin; J R Cypser; Thomas Johnson; Anatoli I Michalski; Sergei I Boyko; Vassily Novoseltsev
Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans.
Mechanisms of ageing and development 2001;122(13):1477-95.
2001: Svetlana V Ukraintseva; Anatoliy Yashin
How individual age-associated changes may influence human morbidity and mortality patterns.
Mechanisms of ageing and development 2001;122(13):1447-60.
2001: Andreas Wienke; Niels V Holm; Axel Skytthe; Anatoliy Yashin
The heritability of mortality due to heart diseases: a correlated frailty model applied to Danish twins.
Twin research : the official journal of the International Society for Twin Studies 2001;4(4):266-74.
2001: Q Tan; Anatoliy Yashin; Else Marie Bladbjerg; M P de Maat; Karen Andersen-Ranberg; Bernard Jeune; K Christensen; James W Vaupel
Variations of cardiovascular disease associated genes exhibit sex-dependent influence on human longevity.
Experimental gerontology 2001;36(8):1303-15.
2001: Giovanna De Benedictis; Qihua Tan; B Jeune; K Christensen; Svetlana V Ukraintseva; Massimiliano Bonafè; Claudio Franceschi; James W Vaupel; Anatoliy Yashin
Recent advances in human gene-longevity association studies.
Mechanisms of ageing and development 2001;122(9):909-20.
2001: O Varcasia; Sabrina Garasto; T Rizza; Karen Andersen-Ranberg; B Jeune; Lise Bathum; Kirill F Andreev; Qihua Tan; Anatoliy Yashin; Massimiliano Bonafè; Claudio Franceschi; Giovanna De Benedictis
Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus.
Annals of human genetics 2001;65(Pt 4):371-6.
2001: Vladimir N Anisimov; Natalia Yu Zavarzina; Mark A Zabezhinski; Irina G Popovich; OA Zimina; A V Shtylick; Alexander V Arutjunyan; Tatiana I Oparina; VM Prokopenko; A I Mikhalski; Anatoliy Yashin
Melatonin increases both life span and tumor incidence in female CBA mice.
The journals of gerontology. Series A, Biological sciences and medical sciences 2001;56(7):B311-23.
2001: Giuseppina Carrieri; Massimiliano Bonafè; M De Luca; Giuseppina Rose; O Varcasia; Amalia C Bruni; Raffaele Maletta; Benedetta Nacmias; Sandro Sorbi; F Corsonello; Emidio Feraco; Kirill F Andreev; Anatoliy Yashin; Claudio Franceschi; Giovanna De Benedictis
Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease.
Human genetics 2001;108(3):194-8.
2001: Anatoli I Michalski; Thomas Johnson; J R Cypser; Anatoliy Yashin
Heating stress patterns in Caenorhabditis elegans longevity and survivorship.
Biogerontology 2001;2(1):35-44.
2001: Vassily Novoseltsev; Janna A Novoseltseva; Anatoliy Yashin
A homeostatic model of oxidative damage explains paradoxes observed in earlier aging experiments: a fusion and extension of older theories of aging.
Biogerontology 2001;2(2):127-38.
2001: V N Anisimov; V K Khavinson; A I Mikhalski; Anatoliy Yashin
Effect of synthetic thymic and pineal peptides on biomarkers of ageing, survival and spontaneous tumour incidence in female CBA mice.
Mechanisms of ageing and development 2001;122(1):41-68.
2000: Vassily Novoseltsev; J Carey; Pablo Liedo; Janna A Novoseltseva; Anatoliy Yashin
Anticipation of oxidative damage decelerates aging in virgin female medflies: hypothesis tested by statistical modeling.
Experimental gerontology 2000;35(8):971-87.
2000: Claudio Franceschi; Silvana Valensin; Massimiliano Bonafè; Giuseppe Paolisso; Anatoliy Yashin; Daniela Monti; Giovanna De Benedictis
The network and the remodeling theories of aging: historical background and new perspectives.
Experimental gerontology 2000;35(6-7):879-96.
2000: Kaare Christensen; Matt McGue; Anatoliy Yashin; Ivan Iachine; N V Holm; James W Vaupel
Genetic and environmental influences on functional abilities in Danish twins aged 75 years and older.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(8):M446-52.
2000: Anatoliy Yashin; Giovanna De Benedictis; James W Vaupel; Qihua Tan; Kirill F Andreev; Ivan Iachine; Massimiliano Bonafe; Silvana Valensin; M De Luca; L Carotenuto; Claudio Franceschi
Genes and longevity: lessons from studies of centenarians.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(7):B319-28.
2000: Alexander Z Begun; Ivan Iachine; Anatoliy Yashin
Genetic nature of individual frailty: comparison of two approaches.
Twin research : the official journal of the International Society for Twin Studies 2000;3(1):51-7.
2000: A Begun; B Desjardins; Ivan Iachine; Anatoliy Yashin
Multivariate frailty model with a major gene: application to genealogical data.
Studies in health technology and informatics 2000;77():412-6.
2000: Andreas Wienke; Kaare Christensen; Niels V Holm; Anatoliy Yashin
Heritability of death from respiratory diseases: an analysis of Danish twin survival data using a correlated frailty model.
Studies in health technology and informatics 2000;77():407-11.
2000: S M Zuev; Anatoliy Yashin; Kenneth G Manton; E Dowd; I B Pogojev; R N Usmanov
Vitality index in survival modeling: how physiological aging influences mortality.
The journals of gerontology. Series A, Biological sciences and medical sciences 2000;55(1):B10-9.
1999: Anatoliy Yashin; Giovanna De Benedictis; James W Vaupel; Qihua Tan; Kirill F Andreev; Ivan Iachine; Massimiliano Bonafe; M DeLuca; Silvana Valensin; L Carotenuto; Claudio Franceschi
Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevity.
American journal of human genetics 1999;65(4):1178-93.
1999: Anatoliy Yashin; Alexander Z Begun; Ivan Iachine
Genetic factors in susceptibility to death: a comparative analysis of bivariate survival models.
Journal of epidemiology and biostatistics 1999;4(1):53-60.
1999: Anatoliy Yashin; Ivan Iachine; J R Harris
Half of the variation in susceptibility to mortality is genetic: findings from Swedish twin survival data.
Behavior genetics 1999;29(1):11-9.
1999: Anatoliy Yashin; Ivan Iachine
What difference does the dependence between durations make? Insights for population studies of aging.
Lifetime data analysis 1999;5(1):5-22.
1998: Ivan Iachine; Niels V Holm; J R Harris; Alexander Z Begun; M K Iachina; M Laitinen; Jaakko Kaprio; Anatoliy Yashin
How heritable is individual susceptibility to death? The results of an analysis of survival data on Danish, Swedish and Finnish twins.
Twin research : the official journal of the International Society for Twin Studies 1998;1(4):196-205.
1998: Giovanna De Benedictis; L Carotenuto; Giuseppina Carrieri; M De Luca; E Falcone; Giuseppina Rose; S Cavalcanti; F Corsonello; Emidio Feraco; Giovannella Baggio; S Bertolini; Daniela Mari; R Mattace; Anatoliy Yashin; Massimiliano Bonafè; Claudio Franceschi
Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).
European journal of human genetics : EJHG 1998;6(6):534-41.
1998: James W Vaupel; James R Carey; Kaare Christensen; Thomas Johnson; Anatoliy Yashin; Niels V Holm; Ivan Iachine; V Kannisto; Aziz A Khazaeli; Pablo Liedo; Valter D Longo; Y Zeng; K G Manton; James W Curtsinger
Biodemographic trajectories of longevity.
Science (New York, N.Y.) 1998;280(5365):855-60.
1998: Anatoliy Yashin; Ivan Iachine; Kaare Christensen; Niels V Holm; James W Vaupel
The genetic component of discrete disability traits: an analysis using liability models with age-dependent thresholds.
Behavior genetics 1998;28(3):207-14.
1998: Giovanna De Benedictis; L Carotenuto; Giuseppina Carrieri; M De Luca; E Falcone; Giuseppina Rose; Anatoliy Yashin; Massimiliano Bonafè; Claudio Franceschi
Age-related changes of the 3'APOB-VNTR genotype pool in ageing cohorts.
Annals of human genetics 1998;62(Pt 2):115-22.
1997: Anatoliy Yashin; I A Iachine
How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach.
Demography 1997;34(1):31-48.
1996: Kaare Christensen; James W Vaupel; Niels V Holm; Anatoliy Yashin
[Mortality among twins after the age of six: the programming hypothesis versus the twin-method].
Ugeskrift for laeger 1996;158(51):7415-9.
1996: Charlotte Leboeuf-Yde; Anatoliy Yashin; torsten lauritzen
Does smoking cause low back pain? Results from a population-based study.
Journal of manipulative and physiological therapeutics 1996;19(2):99-108.
1995: Charlotte Leboeuf-Yde; Anatoliy Yashin
Smoking and low back pain: is the association real?
Journal of manipulative and physiological therapeutics 1995;18(7):457-63.
1995: Anatoliy Yashin; Ivan Iachine
How long can humans live? Lower bound for biological limit of human longevity calculated from Danish twin data using correlated frailty model.
Mechanisms of ageing and development 1995;80(3):147-69.
1995: Kaare Christensen; James W Vaupel; Niels V Holm; Anatoliy Yashin
Mortality among twins after age 6: fetal origins hypothesis versus twin method.
BMJ (Clinical research ed.) 1995;310(6977):432-6.
1995: Anatoliy Yashin; Ivan Iachine
Survival of related individuals: an extension of some fundamental results of heterogeneity analysis.
Mathematical population studies 1995;5(4):321-39, 377.
1995: Anatoliy Yashin; James W Vaupel; Ivan Iachine
Correlated individual frailty: an advantageous approach to survival analysis of bivariate data.
Mathematical population studies 1995;5(2):145-59, 183.
1995: Anatoliy Yashin; K G Manton; M A Woodbury; E Stallard
The effects of health histories on stochastic process models of aging and mortality.
Journal of mathematical biology 1995;34(1):1-16.
1995: Anatoliy Yashin; Ivan Iachine
Genetic analysis of durations: correlated frailty model applied to survival of Danish twins.
Genetic epidemiology 1995;12(5):529-38.
1994: J W Wood; Darryl J Holman; Anatoliy Yashin; R J Peterson; M Weinstein; M C Chang
A multistate model of fecundability and sterility.
Demography 1994;31(3):403-26.
1994: Anatoliy Yashin; James W Vaupel; Ivan Iachine
A duality in aging: the equivalence of mortality models based on radically different concepts.
Mechanisms of ageing and development 1994;74(1-2):1-14.
1993: K G Manton; G Lowrimore; Anatoliy Yashin
Methods for combining ancillary data in stochastic compartment models of cancer mortality: generalization of heterogeneity models.
Mathematical population studies 1993;4(2):133-47, 149.
1989: Anatoliy Yashin; K G Manton; E Stallard
The propagation of uncertainty in human mortality processes operating in stochastic environments.
Theoretical population biology 1989;35(2):119-41.
1988: M A Woodbury; Kenneth G Manton; Anatoliy Yashin
Estimating hidden morbidity via its effect on mortality and disability.
Statistics in medicine 1988;7(1-2):325-36.
1987: G Caselli; J Vallin; James W Vaupel; Anatoliy Yashin
Age-specific mortality trends in France and Italy since 1900: period and cohort effects.
European journal of population = Revue européenne de démographie 1987;3(1):33-60.
1987: James W Vaupel; Anatoliy Yashin
Targeting lifesaving: demographic linkages between population structure and life expectancy.
European journal of population = Revue européenne de démographie 1987;2(3/4):335-60.
1987: James W Vaupel; Anatoliy Yashin
Repeated resuscitation: how lifesaving alters life tables.
Demography 1987;24(1):123-35.
1987: James W Vaupel; Anatoliy Yashin; K G Manton
Debilitation's aftermath: stochastic process models of mortality.
Mathematical population studies 1987;1(1):21-48.
1986: Anatoliy Yashin; K G Manton; E Stallard
Dependent competing risks: a stochastic process model.
Journal of mathematical biology 1986;24(2):119-40.
1985: James W Vaupel; Anatoliy Yashin
Heterogeneity's ruses: some surprising effects of selection on population dynamics.
The American statistician 1985;39(3):176-85.
1985: Anatoliy Yashin; K G Manton; James W Vaupel
Mortality and aging in a heterogeneous population: a stochastic process model with observed and unobserved variables.
Theoretical population biology 1985;27(2):154-75.
1985: G Caselli; James W Vaupel; Anatoliy Yashin
Mortality in Italy: contours of a century of evolution.
Genus 1985;41(1-2):39-55.