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Marzia Capelletti

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Chemicals & Drugs

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Physiology

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Alexis B Cortot; Dalia Ercan; Nathanael S Gray; Claire E Repellin; Takeshi Shimamura; Kwok-Kin Wong; Kreshnik Zejnullahu; Marzia Capelletti; James G Christensen; Pasi A Janne
Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway.
Dalia Ercan; Levi A Garraway; Eva M Goetz; Nathanael S Gray; Elena V Ivanova; Mohit Butaney; Marzia Capelletti; Matthew J Lazzara; Anthony Letai; Ophélia Maertens; Calixte S Monast; Joan Montero; Christine A Pratilas; Claire Repellin; Andrew Rogers; Neal Rosen; Takeshi Shimamura; Lynette Sholl; Madhavi Tadi; Kwok-Kin Wong; Chunxiao Xu; Masahiko Yanagita; Pasi A Janne
Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors.
Pasi A Janne; Robert Kratzke; Marzia Capelletti; Jeffrey Crawford; Martin J Edelman; Lin Gu; Mark A Socinski; Thomas E Stinchcombe; Miguel A Villalona-Calero; Everett E Vokes; Xiaofei Wang; Vincent A Miller
Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial.

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All Publications

2013: Alexis B Cortot; Dalia Ercan; Nathanael S Gray; Claire E Repellin; Takeshi Shimamura; Kwok-Kin Wong; Kreshnik Zejnullahu; Marzia Capelletti; James G Christensen; Pasi A Janne
Resistance to irreversible EGF receptor tyrosine kinase inhibitors through a multistep mechanism involving the IGF1R pathway.
Cancer research 2013;73(2):834-43.
2012: Dalia Ercan; Levi A Garraway; Eva M Goetz; Nathanael S Gray; Elena V Ivanova; Mohit Butaney; Marzia Capelletti; Matthew J Lazzara; Anthony Letai; Ophélia Maertens; Calixte S Monast; Joan Montero; Christine A Pratilas; Claire Repellin; Andrew Rogers; Neal Rosen; Takeshi Shimamura; Lynette Sholl; Madhavi Tadi; Kwok-Kin Wong; Chunxiao Xu; Masahiko Yanagita; Pasi A Janne
Reactivation of ERK signaling causes resistance to EGFR kinase inhibitors.
Cancer discovery 2012;2(10):934-47.
2012: Pasi A Janne; Robert Kratzke; Marzia Capelletti; Jeffrey Crawford; Martin J Edelman; Lin Gu; Mark A Socinski; Thomas E Stinchcombe; Miguel A Villalona-Calero; Everett E Vokes; Xiaofei Wang; Vincent A Miller
Randomized phase II trial of erlotinib alone or with carboplatin and paclitaxel in patients who were never or light former smokers with advanced lung adenocarcinoma: CALGB 30406 trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(17):2063-9.
2012: Sinead Cuffe; Caroline Domerg; Monia Ezzalfani; Stephen Graziano; Pasi A Janne; Jean-Pierre Pignon; Lesley Seymour; Abderrahmane Bourredjem; Ronald Burkes; Marzia Capelletti; Elizabeth Strevel; Ming-Sound Tsao; Frances A Shepherd
A pooled exploratory analysis of the effect of tumor size and KRAS mutations on survival benefit from adjuvant platinum-based chemotherapy in node-negative non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(6):963-72.
2012: Mai He; Pasi A Janne; Mark G Kris; Marc Ladanyi; Vincent A Miller; Khedoudja Nafa; Maria E Arcila; Marzia Capelletti; Michael J Eck; Michelle S Ginsberg; Cai-Hong Yun; Binsheng Zhao; Geoffrey R Oxnard
EGFR exon 19 insertions: a new family of sensitizing EGFR mutations in lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(6):1790-7.
2011: Takaaki Sasaki; Takeshi Shimamura; Magda Stumpfova; Stanislawa Weremowicz; Keith Wilner; Kwok-Kin Wong; Yun Xiao; Masahiko Yanagita; Wei Zheng; Mohit Butaney; Marzia Capelletti; James G Christensen; Jinyan Du; Michael J Eck; Dalia Ercan; Nathanael S Gray; Stephanie Heon; Jussi Koivunen; Christopher Lathan; Neal Lindeman; J Paul Marcoux; Sarah Nikiforow; Atsuko Ogino; Katsuhiro Okuda; Scott J Rodig; Pasi A Janne
A novel ALK secondary mutation and EGFR signaling cause resistance to ALK kinase inhibitors.
Cancer research 2011;71(18):6051-60.
2010: Takaaki Sasaki; Katsuhiro Okuda; Wei Zheng; James E Butrynski; Marzia Capelletti; Liping Wang; Nathanael S Gray; Keith Wilner; James G Christensen; George D Demetri; Geoffrey I Shapiro; Scott J Rodig; Michael J Eck; Pasi A Janne
The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancers.
Cancer research 2010;70(24):10038-43.
2010: Zhao Chen; Takaaki Sasaki; Xiaohong Tan; Julian Carretero; Takeshi Shimamura; Danan Li; Chunxiao Xu; Yuchuan Wang; Guillaume O Adelmant; Marzia Capelletti; Hyun Joo Lee; Scott J Rodig; Christa Borgman; Seung-Il Park; Hyeong Ryul Kim; Robert F Padera; Jarrod A Marto; Nathanael S Gray; Andrew L Kung; Geoffrey I Shapiro; Pasi A Janne; Kwok-Kin Wong
Inhibition of ALK, PI3K/MEK, and HSP90 in murine lung adenocarcinoma induced by EML4-ALK fusion oncogene.
Cancer research 2010;70(23):9827-36.
2010: James E Butrynski; David R D'Adamo; Jason L Hornick; Paola Dal Cin; Cristina R Antonescu; Suresh C Jhanwar; Marc Ladanyi; Marzia Capelletti; Scott J Rodig; Nikhil H Ramaiya; Eunice L Kwak; Jeffrey W Clark; Keith D Wilner; James G Christensen; Pasi A Janne; ROBERT G MAKI; George D Demetri; Geoffrey I Shapiro
Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.
The New England journal of medicine 2010;363(18):1727-33.
2010: L M Flores; D W Kindelberger; Azra H Ligon; Marzia Capelletti; M Fiorentino; Massimo Loda; E S Cibas; Pasi A Janne; Ian Krop
Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer.
British journal of cancer 2010;102(10):1495-502.
2010: Marcello Tiseo; Giulio Rossi; Marzia Capelletti; Giuliana Sartori; Elena Spiritelli; Alessandro Marchioni; Cecilia Bozzetti; giuseppe de palma; Costanza Lagrasta; Nicoletta Campanini; Roberta Camisa; Luca Boni; Vittorio Franciosi; Guido Rindi; Andrea Ardizzoni
Predictors of gefitinib outcomes in advanced non-small cell lung cancer (NSCLC): study of a comprehensive panel of molecular markers.
Lung cancer (Amsterdam, Netherlands) 2010;67(3):355-60.
2010: Alexa B Turke; Kreshnik Zejnullahu; Yi-Long Wu; Youngchul Song; Dora Dias-Santagata; Eugene Lifshits; Luca Toschi; Andrew Rogers; Tony Shu Kam Mok; Lecia Sequist; Neal Lindeman; Carly Murphy; Sara Akhavanfard; Beow Y Yeap; Yun Xiao; Marzia Capelletti; A John Iafrate; Charles Lee; James G Christensen; Jeffrey A Engelman; Pasi A Janne
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.
Cancer cell 2010;17(1):77-88.
2009: Wenjun Zhou; Dalia Ercan; Liang Chen; Cai-Hong Yun; Danan Li; Marzia Capelletti; Alexis B Cortot; Lucian R Chirieac; Roxana E Iacob; Robert F Padera; John R Engen; Kwok-Kin Wong; Michael J Eck; Nathanael S Gray; Pasi A Janne
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M.
Nature 2009;462(7276):1070-4.
2009: Silvia La Monica; Maricla Galetti; Roberta R Alfieri; Andrea Cavazzoni; Andrea Ardizzoni; Marcello Tiseo; Marzia Capelletti; Matteo Goldoni; Sara Tagliaferri; Antonio Mutti; Claudia Fumarola; Mara A Bonelli; daniele generali; Pier Giorgio Petronini
Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines.
Biochemical pharmacology 2009;78(5):460-8.
2008: Marcello Tiseo; Marzia Capelletti; giuseppe de palma; Vittorio Franciosi; Andrea Cavazzoni; Paola Mozzoni; Roberta R Alfieri; Matteo Goldoni; Maricla Galetti; Beatrice Bortesi; Cecilia Bozzetti; Maura Loprevite; Luca Boni; Roberta Camisa; Guido Rindi; Pier Giorgio Petronini; Andrea Ardizzoni
Epidermal growth factor receptor intron-1 polymorphism predicts gefitinib outcome in advanced non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(10):1104-11.
2008: Marcello Tiseo; Elena Spiritelli; Marzia Capelletti; Guido Rindi; Andrea Ardizzoni
Refractory pleural small cell carcinoma in never smoker. A case report.
Tumori 2008;94(3):434-6.
2008: Antonino Musolino; Nadia Naldi; Beatrice Bortesi; Debora Pezzuolo; Marzia Capelletti; Gabriele Missale; Diletta Laccabue; Alessandro Zerbini; Roberta Camisa; Giancarlo Bisagni; Tauro Maria Neri; Andrea Ardizzoni
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(11):1789-96.
2007: Maura Loprevite; Marcello Tiseo; maurizio chiaramondia; Marzia Capelletti; Cecilia Bozzetti; Beatrice Bortesi; Nadia Naldi; Rita Nizzoli; Patrizia Dadati; Annalisa Kunkl; Daniela Zennaro; Costanza Lagrasta; Nicoletta Campanini; Elena Spiritelli; Roberta Camisa; Francesco Grossi; Guido Rindi; Vittorio Franciosi; Andrea Ardizzoni
Buccal mucosa cells as in vivo model to evaluate gefitinib activity in patients with advanced non small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(21):6518-26.
2007: Antonino Musolino; Maria A Bella; Beatrice Bortesi; Maria Michiara; Nadia Naldi; Paola Zanelli; Marzia Capelletti; Debora Pezzuolo; Roberta Camisa; Mario Savi; Tauro M Neri; Andrea Ardizzoni
BRCA mutations, molecular markers, and clinical variables in early-onset breast cancer: a population-based study.
Breast (Edinburgh, Scotland) 2007;16(3):280-92.
2006: Alessandra Vottero; Vincenzo Rochira; Marzia Capelletti; Isabella Viani; Lucia Zirilli; Tauro M Neri; Cesare Carani; Sergio Bernasconi; Lucia Ghizzoni
Aromatase is differentially expressed in peripheral blood leukocytes from children, and adult female and male subjects.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(3):425-31.
2006: Alessandra Vottero; Marzia Capelletti; Silvia Giuliodori; Isabella Viani; Maria Angela Ziveri; Tauro M Neri; Sergio Bernasconi; Lucia Ghizzoni
Decreased androgen receptor gene methylation in premature pubarche: a novel pathogenetic mechanism?
The Journal of clinical endocrinology and metabolism 2006;91(3):968-72.
2005: Antonino Musolino; Maria Michiara; Maria A Bella; Nadia Naldi; Paola Zanelli; Beatrice Bortesi; Marzia Capelletti; Linda Soldani; Roberta Camisa; Eugenia Martella; Vittorio Franciosi; Mario Savi; Tauro M Neri; Andrea Ardizzoni; Stefano Cascinu
Molecular profile and clinical variables in BRCA1-positive breast cancers. A population-based study.
Tumori 2005;91(6):505-12.
2005: Antonino Musolino; Nadia Naldi; Maria Michiara; Maria A Bella; Paola Zanelli; Beatrice Bortesi; Marzia Capelletti; Mario Savi; Tauro M Neri; Andrea Ardizzoni
A breast cancer patient from Italy with germline mutations in both the BRCA1 and BRCA2 genes.
Breast cancer research and treatment 2005;91(2):203-5.
2004: Paola Mozzoni; giuseppe de palma; Eleonora Scotti; Marzia Capelletti; Antonio Mutti
Characterization of GSTM3 polymorphism by real-time polymerase chain reaction with LightCycler.
Analytical biochemistry 2004;330(1):175-7.