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Dong-Hyun Kim

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Ting Fu; Sung-E Choi; Dong-Hyun Kim; Sunmi Seok; Kelly M Suino-Powell; H Eric Xu; Jongsook Kim Kemper
Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.
Deepthi Kanamaluru; Zhen Xiao; Sungsoon Fang; Sung-E Choi; Dong-Hyun Kim; Timothy D Veenstra; Jongsook Kim Kemper
Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner.
Ji-Yeon Kang; Dooil Kim; Dong-Hyun Kim; Keon-Hee Kim; So-Young Kim; Jae-Gu Pan; Sun-Ha Park; Sun-Mi Shin; Taeho Ahn; Ho Zoon Chae; Youn-Tae Chi; Young Hee Joung; Heung-Chae Jung; Chul-Ho Yun
Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium.

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All Publications

2012: Ting Fu; Sung-E Choi; Dong-Hyun Kim; Sunmi Seok; Kelly M Suino-Powell; H Eric Xu; Jongsook Kim Kemper
Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(40):16137-42.
2011: Deepthi Kanamaluru; Zhen Xiao; Sungsoon Fang; Sung-E Choi; Dong-Hyun Kim; Timothy D Veenstra; Jongsook Kim Kemper
Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner.
Molecular and cellular biology 2011;31(7):1540-50.
2011: Ji-Yeon Kang; Dooil Kim; Dong-Hyun Kim; Keon-Hee Kim; So-Young Kim; Jae-Gu Pan; Sun-Ha Park; Sun-Mi Shin; Taeho Ahn; Ho Zoon Chae; Youn-Tae Chi; Young Hee Joung; Heung-Chae Jung; Chul-Ho Yun
Characterization of diverse natural variants of CYP102A1 found within a species of Bacillus megaterium.
AMB Express 2011;1(1):1.
2011: Keon-Hee Kim; Ji-Yeon Kang; Dong-Hyun Kim; Sun-Ha Park; Seon Ha Park; Dooil Kim; Ki Deok Park; Young Ju Lee; Heung-Chae Jung; Jae-Gu Pan; Taeho Ahn; Chul-Ho Yun
Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(1):140-50.
2010: Bhaskar Ponugoti; Dong-Hyun Kim; Zhen Xiao; Zachary Smith; Ji Miao; Mengwei Zang; Shwu-Yuan Wu; Cheng-Ming Chiang; Timothy D Veenstra; Jongsook Kim Kemper
SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism.
The Journal of biological chemistry 2010;285(44):33959-70.
2010: Sun-Ha Park; Dong-Hyun Kim; Dooil Kim; Dong-Hyun Kim; Heung-Chae Jung; Jae-Gu Pan; Taeho Ahn; Donghak Kim; Chul-Ho Yun
Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(5):732-9.
2010: Sung-Kun Yim; Dong-Hyun Kim; Heung-Chae Jung; Jae-Gu Pan; Hyung-Sik Kang; Taeho Ahn; Chul-Ho Yun
Surface display of heme- and diflavin-containing cytochrome P450 BM3 in Escherichia coli: a whole cell biocatalyst for oxidation.
Journal of microbiology and biotechnology 2010;20(4):712-7.
2010: Hyun-Hee Jang; Dong-Hyun Kim; Taeho Ahn; Chul-Ho Yun
Functional and conformational modulation of human cytochrome P450 1B1 by anionic phospholipids.
Archives of biochemistry and biophysics 2010;493(2):143-50.
2009: Dong-Hyun Kim; Taeho Ahn; Heung-Chae Jung; Jae-Gu Pan; Chul-Ho Yun
Generation of the human metabolite piceatannol from the anticancer-preventive agent resveratrol by bacterial cytochrome P450 BM3.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(5):932-6.
2009: Dong-Hyun Kim; Sung-Kun Yim; Keon-Hee Kim; Taeho Ahn; Chul-Ho Yun
Continuous spectrofluorometric and spectrophotometric assays for NADPH-cytochrome P450 reductase activity using 5-cyano-2,3-ditolyl tetrazolium chloride.
Biotechnology letters 2009;31(2):271-5.
2008: Dong-Hyun Kim; Keon-Hee Kim; Dae-Hwan Kim; Kwang-Hyeon Liu; Heung-Chae Jung; Jae-Gu Pan; Chul-Ho Yun
Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(11):2166-70.
2008: Dong-Hyun Kim; Keon-Hee Kim; Emre M Isin; F Peter Guengerich; Ho Zoon Chae; Taeho Ahn; Chul-Ho Yun
Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli.
Protein expression and purification 2008;57(2):188-200.
2007: Keon-Hee Kim; Dong-Hyun Kim; Hyun-Hee Jang; Mihee Kim; Dong-Hyun Kim; Joon-Sik Kim; Jeong-Il Kim; Ho Zoon Chae; Taeho Ahn; Chul-Ho Yun
Lateral segregation of anionic phospholipids in model membranes induced by cytochrome P450 2B1: bi-directional coupling between CYP2B1 and anionic phospholipid.
Archives of biochemistry and biophysics 2007;468(2):226-33.
2007: Chul-Ho Yun; Keon-Hee Kim; Dong-Hyun Kim; Heung-Chae Jung; Jae-Gu Pan
The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities.
Trends in biotechnology 2007;25(7):289-98.
2006: Chul-Ho Yun; Sung-Kun Yim; Dong-Hyun Kim; Taeho Ahn
Functional expression of human cytochrome P450 enzymes in Escherichia coli.
Current drug metabolism 2006;7(4):411-29.
2006: Keon-Hee Kim; Emre M Isin; Chul-Ho Yun; Dong-Hyun Kim; F Peter Guengerich
Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
The FEBS journal 2006;273(10):2223-31.