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Lakshmi Santhanam

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

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Disorders

Vasodilation

Physiology

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Publications

TOP 3
Caroline J Smith; Lakshmi Santhanam; Lacy M Alexander
Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans.
Simran K Jandu; Daniel Nyhan; Alina Pak; Alexey M Belkin; Dan E Berkowitz; Nicholas Flavahan; Baris Sevinc; Alanah K Webb; Lakshmi Santhanam
Nitric oxide regulates tissue transglutaminase localization and function in the vasculature.
Timothy J George; Simran K Jandu; Lakshmi Santhanam; George J Arnaoutakis; Claude A Beaty; Dan E Berkowitz; Ashish S Shah
Inhaled hydrogen sulfide improves graft function in an experimental model of lung transplantation.

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All Publications

2013: Caroline J Smith; Lakshmi Santhanam; Lacy M Alexander
Rho-Kinase activity and cutaneous vasoconstriction is upregulated in essential hypertensive humans.
Microvascular research 2013;87():58-64.
2013: Simran K Jandu; Daniel Nyhan; Alina Pak; Alexey M Belkin; Dan E Berkowitz; Nicholas Flavahan; Baris Sevinc; Alanah K Webb; Lakshmi Santhanam
Nitric oxide regulates tissue transglutaminase localization and function in the vasculature.
Amino acids 2013;44(1):261-9.
2012: Timothy J George; Simran K Jandu; Lakshmi Santhanam; George J Arnaoutakis; Claude A Beaty; Dan E Berkowitz; Ashish S Shah
Inhaled hydrogen sulfide improves graft function in an experimental model of lung transplantation.
The Journal of surgical research 2012;178(2):593-600.
2012: Timothy J George; Simran K Jandu; Lakshmi Santhanam; George J Arnaoutakis; Claude A Beaty; Dan E Berkowitz; Ashish S Shah
Hydrogen sulfide decreases reactive oxygen in a model of lung transplantation.
The Journal of surgical research 2012;178(1):494-501.
2012: Mehnaz Khan; Daniel Nyhan; Sungwoo Ryoo; Lakshmi Santhanam; Karl H Schuleri; Artin A Shoukas; Jochen Steppan; Eric Tuday; Karl H Schuleri; Tal Berkowitz; Lukasz Bugaj; Dan E Berkowitz
Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve.
European journal of applied physiology 2012;112(8):2933-41.
2012: Rebecca S Bruning; Dan E Berkowitz; W Larry Kenney; Lakshmi Santhanam; Caroline J Smith; Anna E Stanhewicz; Lacy A Holowatz
Endothelial nitric oxide synthase mediates cutaneous vasodilation during local heating and is attenuated in middle-aged human skin.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(12):2019-26.
2011: Caroline J Smith; Anna Stanhewicz; Dan E Berkowitz; Rebecca S Bruning; Lakshmi Santhanam; Lacy A Holowatz
Upregulation of inducible nitric oxide synthase contributes to attenuated cutaneous vasodilation in essential hypertensive humans.
Hypertension 2011;58(5):935-42.
2011: Lakshmi Santhanam; Dan E Berkowitz; Alexey M Belkin
Nitric oxide regulates non-classical secretion of tissue transglutaminase.
Communicative & integrative biology 2011;4(5):584-6.
2011: Jessilyn Dunn; Sarah Gutbrod; Simran K Jandu; Alina Pak; Dan E Berkowitz; Anil K Bhunia; Alanah Webb; Lakshmi Santhanam
S-nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase.
Molecular and cellular biochemistry 2011;355(1-2):83-9.
2011: Lacy A Holowatz; Lakshmi Santhanam; Alanah Webb; Dan E Berkowitz; W Larry Kenney
Oral atorvastatin therapy restores cutaneous microvascular function by decreasing arginase activity in hypercholesterolaemic humans.
The Journal of physiology 2011;589(Pt 8):2093-103.
2010: Lakshmi Santhanam; Eric C Tuday; Alanah K Webb; Phillip Dowzicky; Jae Hyung Kim; Young Jun Oh; Gautam Sikka; Maggie Kuo; Marc K Halushka; Anne M Macgregor; Jessilyn Dunn; Sarah Gutbrod; David Yin; Artin A Shoukas; Daniel Nyhan; Nicholas Flavahan; Alexey M Belkin; Dan E Berkowitz
Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness.
Circulation research 2010;107(1):117-25.
2010: Kevin G Soucy; Hyun Kyo Lim; David O Attarzadeh; Lakshmi Santhanam; Jae Hyung Kim; Anil K Bhunia; Baris Sevinc; Sungwoo Ryoo; Marcelo E Vazquez; Daniel Nyhan; Artin A Shoukas; Dan E Berkowitz
Dietary inhibition of xanthine oxidase attenuates radiation-induced endothelial dysfunction in rat aorta.
Journal of applied physiology (Bethesda, Md. : 1985) 2010;108(5):1250-8.
2009: Jae Hyung Kim; Lukasz J Bugaj; Young Jun Oh; Trinity J Bivalacqua; Sungwoo Ryoo; Kevin G Soucy; Lakshmi Santhanam; Alanah Webb; Andre Camara; Gautam Sikka; Daniel Nyhan; Artin A Shoukas; Monica Ilies; David W Christianson; Hunter C Champion; Dan E Berkowitz
Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;107(4):1249-57.
2009: Caitlin S Thompson-Torgerson; Hunter C Champion; Lakshmi Santhanam; Z Leah Harris; Artin A Shoukas
Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function.
American journal of physiology. Heart and circulatory physiology 2009;296(6):H1926-32.
2008: Lakshmi Santhanam; David W Christianson; Daniel Nyhan; Dan E Berkowitz
Arginase and vascular aging.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(5):1632-42.
2008: Lakshmi Santhanam; Marjan Gucek; Tashalee R Brown; Malini Mansharamani; Sungwoo Ryoo; Christopher A Lemmon; Lewis H Romer; Artin A Shoukas; Dan E Berkowitz; Robert N Cole
Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2008;19(3):295-302.
2008: Sungwoo Ryoo; Gaurav Gupta; Alexandre Benjo; Hyun Kyo Lim; Andre Camara; Gautam Sikka; Hyun Kyo Lim; Jayson Sohi; Lakshmi Santhanam; Kevin G Soucy; Eric Tuday; Ezra Baraban; Monica Ilies; Gary Gerstenblith; Daniel Nyhan; Artin A Shoukas; David W Christianson; Nicholas J Alp; Hunter C Champion; David L Huso; Dan E Berkowitz
Endothelial arginase II: a novel target for the treatment of atherosclerosis.
Circulation research 2008;102(8):923-32.
2007: Lakshmi Santhanam; Hyun Kyo Lim; Hyun Kyoung Lim; Victor Miriel; Tashalee Brown; Meet Patel; Sarit Balanson; Sungwoo Ryoo; Mirinda Anderson; Kaikobad Irani; Firdous A Khanday; Luigi Di Costanzo; Daniel Nyhan; Joshua M Hare; David W Christianson; RICHARD RIVERS; Artin A Shoukas; Dan E Berkowitz
Inducible NO synthase dependent S-nitrosylation and activation of arginase1 contribute to age-related endothelial dysfunction.
Circulation research 2007;101(7):692-702.
2007: Kenji Kasuno; Asma Naqvi; Jeremy Dericco; Tohru Yamamori; Lakshmi Santhanam; Ilwola Mattagajasingh; S Yang; F L Meyskens; Anja Bosserhoff; Kaikobad Irani
Antagonism of p66shc by melanoma inhibitory activity.
Cell death and differentiation 2007;14(8):1414-21.
2007: Kevin G Soucy; Hyun Kyo Lim; Alexandre Benjo; Lakshmi Santhanam; Sungwoo Ryoo; Artin A Shoukas; Marcelo E Vazquez; Dan E Berkowitz
Single exposure gamma-irradiation amplifies xanthine oxidase activity and induces endothelial dysfunction in rat aorta.
Radiation and environmental biophysics 2007;46(2):179-86.
2006: Jochen Steppan; Sungwoo Ryoo; Karl H Schuleri; Chris Gregg; Rani K Hasan; Anthony R White; Lukasz J Bugaj; Mehnaz Khan; Lakshmi Santhanam; Daniel Nyhan; Artin A Shoukas; Joshua M Hare; Dan E Berkowitz
Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(12):4759-64.
2006: Firdous A Khanday; Lakshmi Santhanam; Kenji Kasuno; Tohru Yamamori; Asma Naqvi; Jeremy Dericco; Artem Bugayenko; Ilwola Mattagajasingh; Andrea Disanza; Giorgio Scita; Kaikobad Irani
Sos-mediated activation of rac1 by p66shc.
The Journal of cell biology 2006;172(6):817-22.
2006: Firdous A Khanday; Tohru Yamamori; Ilwola Mattagajasingh; Zhe Zhang; Artem Bugayenko; Asma Naqvi; Lakshmi Santhanam; Nusrat Nabi; Kenji Kasuno; Billy W Day; Kaikobad Irani
Rac1 leads to phosphorylation-dependent increase in stability of the p66shc adaptor protein: role in Rac1-induced oxidative stress.
Molecular biology of the cell 2006;17(1):122-9.
2004: Sylvain Antoniotti; Lakshmi Santhanam; Disha Ahuja; Michael G Hogg; Jonathan S Dordick
Structural diversity of peroxidase-catalyzed oxidation products of o-methoxyphenols.
Organic letters 2004;6(12):1975-8.
2002: David K Johnson; Kurt J Schillinger; David M Kwait; Chambers V Hughes; Erin J McNamara; Fauod Ishmael; Robert W O'Donnell; Ming-Mei Chang; Michael G Hogg; Jonathan S Dordick; Lakshmi Santhanam; Linda M Ziegler; James A Holland
Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols.
Endothelium : journal of endothelial cell research 2002;9(3):191-203.