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Anthony Basile

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Katherine L Nicholson; Robert L Balster; Krystyna Golembiowska; Magdalena Kowalska; Joseph P Tizzano; Phil Skolnick; Anthony Basile
Preclinical evaluation of the abuse potential of the analgesic bicifadine.
Joseph P Tizzano; D Sloan Stribling; Diego Perez-Tilve; Alison M Strack; Andrea Frassetto; Richard Z Chen; Tung M Fong; Lauren P Shearman; Philip Krieter; Matthias H Tschöp; Phil Skolnick; Anthony Basile
The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity.
Dmytro Berezhnoy; Maria C Gravielle; Scott Downing; Emmanuel Kostakis; Anthony Basile; Phil Skolnick; Terrell T Gibbs; David H Farb
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.

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2009: Katherine L Nicholson; Robert L Balster; Krystyna Golembiowska; Magdalena Kowalska; Joseph P Tizzano; Phil Skolnick; Anthony Basile
Preclinical evaluation of the abuse potential of the analgesic bicifadine.
The Journal of pharmacology and experimental therapeutics 2009;330(1):236-48.
2008: Joseph P Tizzano; D Sloan Stribling; Diego Perez-Tilve; Alison M Strack; Andrea Frassetto; Richard Z Chen; Tung M Fong; Lauren P Shearman; Philip Krieter; Matthias H Tschöp; Phil Skolnick; Anthony Basile
The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity.
The Journal of pharmacology and experimental therapeutics 2008;324(3):1111-26.
2008: Dmytro Berezhnoy; Maria C Gravielle; Scott Downing; Emmanuel Kostakis; Anthony Basile; Phil Skolnick; Terrell T Gibbs; David H Farb
Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.
BMC pharmacology 2008;8():11.
2007: Brian A McMillen; J Elizabeth Shank; Kirstin B Jordan; Helen L Williams; Anthony Basile
Effect of DOV 102,677 on the volitional consumption of ethanol by Myers' high ethanol-preferring rat.
Alcoholism, clinical and experimental research 2007;31(11):1866-71.
2007: shengzhou/sheng-zhou wu; Anthony Basile; Steven W Barger
Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP).
Current Alzheimer research 2007;4(3):243-51.
2007: Anthony Basile; Aaron Janowsky; Krystyna Golembiowska; Magdalena Kowalska; Eyal Tam; Morris J Benveniste; Piotr Popik; Agnieszka Nikiforuk; Martyna Krawczyk; Gabriel Nowak; Philip Krieter; Arnold S Lippa; Phil Skolnick; Elena Koustova
Characterization of the antinociceptive actions of bicifadine in models of acute, persistent, and chronic pain.
The Journal of pharmacology and experimental therapeutics 2007;321(3):1208-25.
2007: Phil Skolnick; Anthony Basile
Triple reuptake inhibitors ("broad spectrum" antidepressants).
CNS & neurological disorders drug targets 2007;6(2):141-9.
2006: Piotr Popik; Emmanuel Kostakis; Martyna Krawczyk; Gabriel Nowak; Bernadeta Szewczyk; Philip Krieter; Zhengming Chen; Shelley J Russek; Terrell T Gibbs; David H Farb; Phil Skolnick; Arnold S Lippa; Anthony Basile
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
The Journal of pharmacology and experimental therapeutics 2006;319(3):1244-52.
2006: Piotr Popik; Martyna Krawczyk; Krystyna Golembiowska; Gabriel Nowak; Aaron Janowsky; Phil Skolnick; Arnold S Lippa; Anthony Basile
Pharmacological profile of the "triple" monoamine neurotransmitter uptake inhibitor, DOV 102,677.
Cellular and molecular neurobiology 2006;26(4-6):857-73.
2004: Thomas Seeger; Irina Fedorova; Fang Zheng; Tsuyoshi Miyakawa; Elena Koustova; Jesus Gomeza; Anthony Basile; Christian Alzheimer; Jürgen Wess
M2 muscarinic acetylcholine receptor knock-out mice show deficits in behavioral flexibility, working memory, and hippocampal plasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(45):10117-27.
2004: Anthony Basile; Arnold S Lippa; Phil Skolnick
Anxioselective anxiolytics: can less be more?
European journal of pharmacology 2004;500(1-3):441-51.
2004: raymond bartus; Dwaine F Emerich; Pam Snodgrass-Belt; Karen Fu; Heather Salzberg-Brenhouse; Denise Lafreniere; Leah Novak; Ee-Sing Lo; Thomas Cooper; Anthony Basile
A pulmonary formulation of L-dopa enhances its effectiveness in a rat model of Parkinson's disease.
The Journal of pharmacology and experimental therapeutics 2004;310(2):828-35.
2004: Yanlei Hao; Anthony Basile; Guang Chen; Lei Zhang
Glutamate-induced over-expression of GAD is down-regulated by acetyl-L-carnitine in rat islet cells.
Endocrine research 2004;30(1):107-16.
2003: Masahisa Yamada; Anthony Basile; Irina Fedorova; Weilie Zhang; Alokesh Duttaroy; Yinghong Cui; Kathryn G Lamping; Frank M Faraci; Chu-Xia Deng; Jürgen Wess
Novel insights into M5 muscarinic acetylcholine receptor function by the use of gene targeting technology.
Life sciences 2003;74(2-3):345-53.
2003: raymond bartus; Dwaine F Emerich; Joyce Hotz; Marc Blaustein; Reginald L Dean; Brigido Perdomo; Anthony Basile
Vivitrex, an injectable, extended-release formulation of naltrexone, provides pharmacokinetic and pharmacodynamic evidence of efficacy for 1 month in rats.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(11):1973-82.
2003: Heather C Salzberg-Brenhouse; Er-Yun Chen; Dwaine F Emerich; Sam Baldwin; Ken Hogeland; Sharon Ranelli; Denise Lafreniere; Brigido Perdomo; Leah Novak; Theodora Kladis; Karen Fu; Anthony Basile; Jeffrey Kordower; raymond bartus
Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration.
The Journal of pharmacology and experimental therapeutics 2003;306(1):218-28.
2002: Alokesh Duttaroy; Jesus Gomeza; Jai-Wei Gan; Nasir Siddiqui; Anthony Basile; W Dean Harman; Philip L Smith; Christian Felder; Allan Levey; Jürgen Wess
Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice.
Molecular pharmacology 2002;62(5):1084-93.
2002: Anthony Basile; Irina Fedorova; Agustin Zapata; Xiaoguang Liu; Toni S Shippenberg; Alokesh Duttaroy; Masahisa Yamada; Jürgen Wess
Deletion of the M5 muscarinic acetylcholine receptor attenuates morphine reinforcement and withdrawal but not morphine analgesia.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(17):11452-7.
2002: Weilie Zhang; Masahisa Yamada; Jesus Gomeza; Anthony Basile; Jürgen Wess
Multiple muscarinic acetylcholine receptor subtypes modulate striatal dopamine release, as studied with M1-M5 muscarinic receptor knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(15):6347-52.
2002: Anthony Basile
Direct and indirect enhancement of GABAergic neurotransmission by ammonia: implications for the pathogenesis of hyperammonemic syndromes.
Neurochemistry international 2002;41(2-3):115-22.
2002: Michael G Espey; Anthony Basile; Robert K Heaton; Ronald J Ellis
Increased glutamate in CSF and plasma of patients with HIV dementia.
Neurology 2002;58(9):1439; author reply 1439-40.
2002: Pierre Casellas; Sylvaine Galiegue; Anthony Basile
Peripheral benzodiazepine receptors and mitochondrial function.
Neurochemistry international 2002;40(6):475-86.
2002: Weilie Zhang; Anthony Basile; Jesus Gomeza; Laura A Volpicelli; Allan Levey; Jürgen Wess
Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(5):1709-17.
2002: Yoshitatsu Sei; Anthony Basile
A murine model of retroviral encephalopathy.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2002;Chapter 9():Unit9.8.
2001: Anthony Basile; Elena Koustova; P Ioan; S Rizzoli; Michael A Rogawski; P N Usherwood
IgG isolated from LP-BM5 infected mouse brain activates ionotropic glutamate receptors.
Neurobiology of disease 2001;8(6):1069-81.
2001: Wallace B Mendelson; Anthony Basile
The hypnotic actions of the fatty acid amide, oleamide.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(5 Suppl):S36-9.
2001: Irina Fedorova; A Hashimoto; Robert A Fecik; Michael P Hedrick; LO Hanus; Dale L Boger; Kenner C Rice; Anthony Basile
Behavioral evidence for the interaction of oleamide with multiple neurotransmitter systems.
The Journal of pharmacology and experimental therapeutics 2001;299(1):332-42.
2001: Anthony Basile; K Mullen
Preclinical models of hepatic encephalopathy.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2001;Chapter 9():Unit9.3.
2001: C Hernández-Sánchez; Anthony Basile; Irina Fedorova; H Arima; Bethel Stannard; Ana M Fernandez; Y Ito; Derek LeRoith
Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3549-54.
2001: Elena Koustova; Yoshitatsu Sei; LH Fossom; M L Wei; P N Usherwood; N B Keele; Michael A Rogawski; Anthony Basile
LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor.
The Journal of clinical investigation 2001;107(6):737-44.
2001: Steven W Barger; Anthony Basile
Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.
Journal of neurochemistry 2001;76(3):846-54.
2000: Elena Koustova; Yoshitatsu Sei; T McCarty; Michael G Espey; R Ming; Herbert C Morse; Anthony Basile
Accelerated development of neurochemical and behavioral deficits in LP-BM5 infected mice with targeted deletions of the IFN-gamma gene.
Journal of neuroimmunology 2000;108(1-2):112-21.
2000: R Iida; K Saito; Kiyofumi Yamada; Anthony Basile; K Sekikawa; M Takemura; H Fujii; H Wada; Mitsuru Seishima; Toshitaka Nabeshima
Suppression of neurocognitive damage in LP-BM5-infected mice with a targeted deletion of the TNF-alpha gene.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(7):1023-31.
1999: Wallace B Mendelson; Anthony Basile
The hypnotic actions of oleamide are blocked by a cannabinoid receptor antagonist.
Neuroreport 1999;10(15):3237-9.
1999: Michael G Espey; R J Ellis; R K Heaton; Anthony Basile
Relevance of glutamate levels in the CSF of patients with HIV-1-associated dementia complex.
Neurology 1999;53(5):1144-5.
1999: Y Kustova; A Grinberg; Anthony Basile
Increased blood-brain barrier permeability in LP-BM5 infected mice is mediated by neuroexcitatory mechanisms.
Brain research 1999;839(1):153-63.
1999: JW Allen; SA Ivanova; L Fan; Michael G Espey; Anthony Basile; Alan Faden
Group II metabotropic glutamate receptor activation attenuates traumatic neuronal injury and improves neurological recovery after traumatic brain injury.
The Journal of pharmacology and experimental therapeutics 1999;290(1):112-20.
1999: LO Hanus; H M Fales; T F Spande; Anthony Basile
A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids.
Analytical biochemistry 1999;270(1):159-66.
1999: Anthony Basile; A M Brichta; BD Harris; D Morse; D Coling; Phil Skolnick
Dizocilpine attenuates streptomycin-induced vestibulotoxicity in rats.
Neuroscience letters 1999;265(2):71-4.
1999: Michael G Espey; Anthony Basile
Glutamate augments retrovirus-induced immunodeficiency through chronic stimulation of the hypothalamic-pituitary- adrenal axis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4998-5002.
1999: Anthony Basile; LO Hanus; Wallace B Mendelson
Characterization of the hypnotic properties of oleamide.
Neuroreport 1999;10(5):947-51.
1999: Yoshitatsu Sei; Kathleen L Gallagher; Anthony Basile
Skeletal muscle type ryanodine receptor is involved in calcium signaling in human B lymphocytes.
The Journal of biological chemistry 1999;274(9):5995-6002.
1998: E Anthony Jones; Anthony Basile
Does ammonia contribute to increased GABA-ergic neurotransmission in liver failure?
Metabolic brain disease 1998;13(4):351-60.
1998: Y Kustova; Yoshitatsu Sei; Herbert C Morse; Anthony Basile
The influence of a targeted deletion of the IFNgamma gene on emotional behaviors.
Brain, behavior, and immunity 1998;12(4):308-24.
1998: Michael G Espey; Y Kustova; Yoshitatsu Sei; Anthony Basile
Extracellular glutamate levels are chronically elevated in the brains of LP-BM5-infected mice: a mechanism of retrovirus-induced encephalopathy.
Journal of neurochemistry 1998;71(5):2079-87.
1998: Y Kustova; Michael G Espey; E G Sung; D Morse; Yoshitatsu Sei; Anthony Basile
Evidence of neuronal degeneration in C57B1/6 mice infected with the LP-BM5 leukemia retrovirus mixture.
Molecular and chemical neuropathology / sponsored by the International Society for Neurochemistry and the World Federation of Neurology and research groups on neurochemistry and cerebrospinal fluid 1998;35(1-3):39-59.
1998: Y Kustova; J H Ha; Michael G Espey; Yoshitatsu Sei; D Morse; Anthony Basile
The pattern of neurotransmitter alterations in LP-BM5 infected mice is consistent with glutamatergic hyperactivation.
Brain research 1998;793(1-2):119-26.
1998: Yoshitatsu Sei; Y Kustova; Yong Li; Herbert C Morse; Phil Skolnick; Anthony Basile
The encephalopathy associated with murine acquired immunodeficiency syndrome.
Annals of the New York Academy of Sciences 1998;840():822-34.
1998: Yoshitatsu Sei; LH Fossom; Gertrud Goping; Phil Skolnick; Anthony Basile
Quinolinic acid protects rat cerebellar granule cells from glutamate-induced apoptosis.
Neuroscience letters 1998;241(2-3):180-4.
1997: Robert C Drugan; Anthony Basile; J H Ha; D Healy; R J Ferland
Analysis of the importance of controllable versus uncontrollable stress on subsequent behavioral and physiological functioning.
Brain research. Brain research protocols 1997;2(1):69-74.
1997: Anthony Basile; E Anthony Jones
Ammonia and GABA-ergic neurotransmission: interrelated factors in the pathogenesis of hepatic encephalopathy.
Hepatology (Baltimore, Md.) 1997;25(6):1303-5.
1997: Lidia Kupczyk-Subotkowska; Teruna J Siahaan; Anthony Basile; H S Friedman; P E Higgins; D Song; J M Gallo
Modulation of melphalan resistance in glioma cells with a peripheral benzodiazepine receptor ligand-melphalan conjugate.
Journal of medicinal chemistry 1997;40(11):1726-30.
1997: Yoshitatsu Sei; K Nishida; Y Kustova; Sanford Markey; Herbert C Morse; Anthony Basile
Pentoxifylline decreases brain levels of platelet activating factor in murine AIDS.
European journal of pharmacology 1997;325(1):81-4.
1997: Yong Li; Y Kustova; Yoshitatsu Sei; Anthony Basile
Regional changes in constitutive, but not inducible NOS expression in the brains of mice infected with the LP-BM5 leukemia virus.
Brain research 1997;752(1-2):107-16.
1997: Y Kustova; Michael G Espey; Yoshitatsu Sei; Anthony Basile
Regional decreases [corrected] in AMPA receptor density in mice infected with the LP-BM5 murine leukemia virus.
Neuroreport 1997;8(5):1243-7.
1997: JB Acri; G Wong; T Lyon; Jeffrey M Witkin; Anthony Basile
Localization and pharmacological characterization of pigeon diazepam-insensitive GABAA receptors.
Neuroscience 1997;77(2):371-8.
1997: J H Ha; S Knauer; EJ Moody; E Anthony Jones; Anthony Basile
Direct enhancement of GABA-ergic neurotransmission by ammonia.
Advances in experimental medicine and biology 1997;420():85-94.
1997: E Anthony Jones; Anthony Basile
The involvement of ammonia with the mechanisms that enhance GABA-ergic neurotransmission in hepatic failure.
Advances in experimental medicine and biology 1997;420():75-83.
1996: Y Kustova; Yoshitatsu Sei; Gertrud Goping; Anthony Basile
Gliosis in the LP-BM5 murine leukemia virus-infected mouse: an animal model of retrovirus-induced dementia.
Brain research 1996;742(1-2):271-82.
1996: Anthony Basile; J M Huang; C Xie; D Webster; C Berlin; Phil Skolnick
N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss.
Nature medicine 1996;2(12):1338-43.
1996: Maurizio Anzini; Andrea Cappelli; Salvatore Vomero; Gianluca Giorgi; T Langer; Giancarlo Bruni; M R Romeo; Anthony Basile
Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem.
Journal of medicinal chemistry 1996;39(21):4275-84.
1996: J H Ha; Anthony Basile
Modulation of ligand binding to components of the GABAA receptor complex by ammonia: implications for the pathogenesis of hyperammonemic syndromes.
Brain research 1996;720(1-2):35-44.
1996: Kuniaki Saito; K Suyama; K Nishida; Y Sei; Anthony Basile
Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain.
Neuroscience letters 1996;206(2-3):149-52.
1996: Yoshitatsu Sei; Luke Whitesell; Y Kustova; I A Paul; Herbert C Morse; Phil Skolnick; Anthony Basile
Altered brain fyn kinase in a murine acquired immunodeficiency syndrome.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(2):339-44.
1996: K Nishida; Sanford Markey; Y Kustova; Herbert C Morse; Phil Skolnick; Anthony Basile; Yoshitatsu Sei
Increased brain levels of platelet-activating factor in a murine acquired immune deficiency syndrome are NMDA receptor-mediated.
Journal of neurochemistry 1996;66(1):433-5.
1995: LH Fossom; Anthony Basile; Phil Skolnick
Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition.
Molecular pharmacology 1995;48(6):981-7.
1995: Anthony Basile; K Saito; Yong Li; M P Heyes
The relationship between plasma and brain quinolinic acid levels and the severity of hepatic encephalopathy in animal models of fulminant hepatic failure.
Journal of neurochemistry 1995;64(6):2607-14.
1995: Cihan Yurdaydin; T J Walsh; H D Engler; J H Ha; Yong Li; E Anthony Jones; Anthony Basile
Gut bacteria provide precursors of benzodiazepine receptor ligands in a rat model of hepatic encephalopathy.
Brain research 1995;679(1):42-8.
1995: Cihan Yurdaydin; Yong Li; J H Ha; E Anthony Jones; R Rothman; Anthony Basile
Brain and plasma levels of opioid peptides are altered in rats with thioacetamide-induced fulminant hepatic failure: implications for the treatment of hepatic encephalopathy with opioid antagonists.
The Journal of pharmacology and experimental therapeutics 1995;273(1):185-92.
1995: J H Ha; Yoshitatsu Sei; Anthony Basile
Striatal met-enkephalin and substance P levels are decreased in mice infected with the LP-BM5 murine leukemia virus.
Journal of neurochemistry 1995;64(4):1896-8.
1995: Anthony Basile; K Saito; Hanan Al Mardini; Christopher Oswold Record; R D Hughes; Phillip Harrison; R Williams; Yong Li; M P Heyes
The relationship between plasma and brain quinolinic acid levels and the severity of hepatic encephalopathy.
Gastroenterology 1995;108(3):818-23.
1994: Robert C Drugan; Anthony Basile; J H Ha; R J Ferland
The protective effects of stress control may be mediated by increased brain levels of benzodiazepine receptor agonists.
Brain research 1994;661(1-2):127-36.
1994: Anthony Basile; E A Jones
The involvement of benzodiazepine receptor ligands in hepatic encephalopathy.
Hepatology (Baltimore, Md.) 1994;20(2):541-3.
1994: Bradford Harris; EJ Moody; Anthony Basile; Phil Skolnick
Volatile anesthetics bidirectionally and stereospecifically modulate ligand binding to GABA receptors.
European journal of pharmacology 1994;267(3):269-74.
1994: Yoshitatsu Sei; K J Von Lubitz; Anthony Basile; M M Borner; RC Lin; Phil Skolnick; LH Fossom
Internucleosomal DNA fragmentation in gerbil hippocampus following forebrain ischemia.
Neuroscience letters 1994;171(1-2):179-82.
1994: Anthony Basile; B DeCosta; I A Paul
Multiple [3H]DTG binding sites in guinea pig cerebellum: evidence for the presence of non-specific binding.
European journal of pharmacology 1994;252(2):139-46.
1994: Anthony Basile; Phillip Harrison; R D Hughes; Z Q Gu; L Pannell; A McKinney; E Anthony Jones; R Williams
Relationship between plasma benzodiazepine receptor ligand concentrations and severity of hepatic encephalopathy.
Hepatology (Baltimore, Md.) 1994;19(1):112-21.
1994: E Anthony Jones; Cihan Yurdaydin; Anthony Basile
The GABA hypothesis--state of the art.
Advances in experimental medicine and biology 1994;368():89-101.
1993: K D Mullen; Anthony Basile
Benzodiazepine-receptor antagonists and hepatic encephalopathy: where do we stand?
Gastroenterology 1993;105(3):937-40.
1993: I A Paul; Anthony Basile; Eduardo Rojas; Moussa B H Youdim; B De Costa; Phil Skolnick; Harvey B Pollard; G A Kuijpers
Sigma receptors modulate nicotinic receptor function in adrenal chromaffin cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(12):1171-8.
1993: R I Fryer; P Zhang; R Rios; Z Q Gu; Anthony Basile; Phil Skolnick
Structure-activity relationship studies at the benzodiazepine receptor (BZR): a comparison of the substitutent effects of pyrazoloquinolinone analogs.
Journal of medicinal chemistry 1993;36(11):1669-73.
1993: Cihan Yurdaydin; Z Q Gu; G Nowak; C Fromm; A G Holt; Anthony Basile
Benzodiazepine receptor ligands are elevated in an animal model of hepatic encephalopathy: relationship between brain concentration and severity of encephalopathy.
The Journal of pharmacology and experimental therapeutics 1993;265(2):565-71.
1993: E Anthony Jones; Anthony Basile; Cihan Yurdaydin; P Skolnich
Do benzodiazepine ligands contribute to hepatic encephalopathy?
Advances in experimental medicine and biology 1993;341():57-69.
1993: E Anthony Jones; Cihan Yurdaydin; Anthony Basile
The role of endogenous benzodiazepines in hepatic encephalopathy: animal studies.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1993;2():175-80.
1992: Anthony Basile; I A Paul; A Mirchevich; G Kuijpers; B De Costa
Modulation of (+)-[3H]pentazocine binding to guinea pig cerebellum by divalent cations.
Molecular pharmacology 1992;42(5):882-9.
1992: Anthony Basile; I A Paul; B de Costa
Differential effects of cytochrome P-450 induction on ligand binding to sigma receptors.
European journal of pharmacology 1992;227(1):95-8.
1991: Anthony Basile; R D Hughes; Phillip Harrison; Y Murata; L Pannell; E Anthony Jones; R Williams; Phil Skolnick
Elevated brain concentrations of 1,4-benzodiazepines in fulminant hepatic failure.
The New England journal of medicine 1991;325(7):473-8.
1991: Rafael Moreno-Sanchez; Barbara A Hogue; Concepción Bravo; A H Newman; Anthony Basile; P K Chiang
Inhibition of substrate oxidation in mitochondria by the peripheral-type benzodiazepine receptor ligand AHN 086.
Biochemical pharmacology 1991;41(10):1479-84.
1991: Anthony Basile; E Anthony Jones; Phil Skolnick
The pathogenesis and treatment of hepatic encephalopathy: evidence for the involvement of benzodiazepine receptor ligands.
Pharmacological reviews 1991;43(1):27-71.
1991: Anthony Basile
The contribution of endogenous benzodiazepine receptor ligands to the pathogenesis of hepatic encephalopathy.
Synapse (New York, N.Y.) 1991;7(2):141-50.
1990: Anthony Basile; L Pannell; T Jaouni; S H Gammal; H M Fales; E Anthony Jones; Phil Skolnick
Brain concentrations of benzodiazepines are elevated in an animal model of hepatic encephalopathy.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5263-7.
1990: S H Gammal; Anthony Basile; D Geller; Phil Skolnick; E Anthony Jones
Reversal of the behavioral and electrophysiological abnormalities of an animal model of hepatic encephalopathy by benzodiazepine receptor ligands.
Hepatology (Baltimore, Md.) 1990;11(3):371-8.
1990: Anthony Basile; N L Ostrowski; S H Gammal; E Anthony Jones; Phil Skolnick
The GABAA receptor complex in hepatic encephalopathy. Autoradiographic evidence for the presence of elevated levels of a benzodiazepine receptor ligand.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1990;3(1):61-71.
1990: E Anthony Jones; Anthony Basile; Kevin D Mullen; S H Gammal
Flumazenil: potential implications for hepatic encephalopathy.
Pharmacology & therapeutics 1990;45(3):331-43.
1990: E Anthony Jones; Anthony Basile; Phil Skolnick
Hepatic encephalopathy, GABA-ergic neurotransmission and benzodiazepine receptor ligands.
Advances in experimental medicine and biology 1990;272():121-34.
1990: Anthony Basile; N L Ostrowski; S H Gammal; E Anthony Jones; Phil Skolnick
The involvement of the benzodiazepine receptor in hepatic encephalopathy: evidence for the presence of a benzodiazepine receptor ligand.
Advances in biochemical psychopharmacology 1990;46():189-200.
1989: Anthony Basile; S H Gammal; E Anthony Jones; Phil Skolnick
GABAA receptor complex in an experimental model of hepatic encephalopathy: evidence for elevated levels of an endogenous benzodiazepine receptor ligand.
Journal of neurochemistry 1989;53(4):1057-63.
1989: E Anthony Jones; Phil Skolnick; S H Gammal; Anthony Basile; Kevin D Mullen
NIH conference. The gamma-aminobutyric acid A (GABAA) receptor complex and hepatic encephalopathy. Some recent advances.
Annals of internal medicine 1989;110(7):532-46.
1989: G T Bolger; Amy Hauck Newman; Kenner C Rice; H W Lueddens; Anthony Basile; Phil Skolnick
Characterization of the effects of AHN 086, an irreversible ligand of "peripheral" benzodiazepine receptors, on contraction in guinea-pig atrial and ileal longitudinal smooth muscle.
Canadian journal of physiology and pharmacology 1989;67(2):126-34.
1989: Anthony Basile; G T Bolger; H W Lueddens; Phil Skolnick
Electrophysiological actions of Ro5-4864 on cerebellar Purkinje neurons: evidence for "peripheral" benzodiazepine receptor-mediated depression.
The Journal of pharmacology and experimental therapeutics 1989;248(1):463-9.
1988: Anthony Basile; S H Gammal
Evidence for the involvement of the benzodiazepine receptor complex in hepatic encephalopathy. Implications for treatment with benzodiazepine receptor antagonists.
Clinical neuropharmacology 1988;11(5):401-22.
1988: R C Drugan; Anthony Basile; Jacqueline N Crawley; S M Paul; P Skolnick
Characterization of stress-induced alterations in [3H] Ro5-4864 binding to peripheral benzodiazepine receptors in rat heart and kidney.
Pharmacology, biochemistry, and behavior 1988;30(4):1015-20.
1988: Anthony Basile; S H Gammal; Kevin D Mullen; E Anthony Jones; Phil Skolnick
Differential responsiveness of cerebellar Purkinje neurons to GABA and benzodiazepine receptor ligands in an animal model of hepatic encephalopathy.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1988;8(7):2414-21.
1988: G T Bolger; P Lesieur; Anthony Basile; Phil Skolnick
Modulation of neurotransmitter metabolism by dihydropyridine calcium channel ligands in mouse brain.
Brain research 1988;438(1-2):101-7.
1988: Anthony Basile; H W Lueddens; Phil Skolnick
Regulation of renal peripheral benzodiazepine receptors by anion transport inhibitors.
Life sciences 1988;42(6):715-26.
1988: Anthony Basile; Phil Skolnick
Tissue specific regulation of "peripheral-type" benzodiazepine receptor density after chemical sympathectomy.
Life sciences 1988;42(3):273-83.
1987: Anthony Basile; B A Weissman; Phil Skolnick
Maximal electroshock increases the density of [3H]Ro 5-4864 binding to mouse cerebral cortex.
Brain research bulletin 1987;19(1):1-7.
1987: Anthony Basile; P Skolnick
Preservation of "peripheral" benzodiazepine receptors: differential effects of freezing on [3H]Ro 5-4864 and [3H]PK 11195 binding.
Journal of pharmacological methods 1987;17(2):149-56.
1987: Anthony Basile; N L Ostrowski; P Skolnick
Aldosterone-reversible decrease in the density of renal peripheral benzodiazepine receptors in the rat after adrenalectomy.
The Journal of pharmacology and experimental therapeutics 1987;240(3):1006-13.
1987: M L Trudell; Anthony Basile; H E Shannon; Phil Skolnick; James M Cook
Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands.
Journal of medicinal chemistry 1987;30(3):456-8.
1987: G T Bolger; Anthony Basile; Aaron Janowsky; S M Paul; P Skolnick
Regulation of dihydropyridine calcium antagonist binding sites in the rat hippocampus following neurochemical lesions.
Journal of neuroscience research 1987;17(3):285-90.
1987: R C Drugan; Anthony Basile; Jacqueline N Crawley; S M Paul; P Skolnick
"Peripheral" benzodiazepine binding sites in the Maudsley reactive rat: selective decrease confined to peripheral tissues.
Brain research bulletin 1987;18(1):143-5.
1986: Anthony Basile; David Klein; P Skolnick
Characterization of benzodiazepine receptors in the bovine pineal gland: evidence for the presence of an atypical binding site.
Brain research 1986;387(2):127-35.
1986: R C Drugan; Anthony Basile; Jacqueline N Crawley; S M Paul; P Skolnick
Inescapable shock reduces [3H]Ro 5-4864 binding to "peripheral-type" benzodiazepine receptors in the rat.
Pharmacology, biochemistry, and behavior 1986;24(6):1673-7.
1986: Anthony Basile; P Skolnick
Subcellular localization of "peripheral-type" binding sites for benzodiazepines in rat brain.
Journal of neurochemistry 1986;46(1):305-8.
1985: G T Bolger; B A Weissman; H Lueddens; Anthony Basile; C R Mantione; J E Barrett; J M Witkin; S M Paul; Phil Skolnick
Late evolutionary appearance of 'peripheral-type' binding sites for benzodiazepines.
Brain research 1985;338(2):366-70.
1985: M R Palmer; Anthony Basile; W R Proctor; R C Baker; T V Dunwiddie
Ethanol tolerance of cerebellar purkinje neurons from selectively outbred mouse lines: in vivo and in vitro electrophysiological investigations.
Alcoholism, clinical and experimental research 1985;9(3):291-6.
1985: Anthony Basile; S M Paul; P Skolnick
Adrenalectomy reduces the density of 'peripheral-type' binding sites for benzodiazepines in the rat kidney.
European journal of pharmacology 1985;110(1):149-50.
1984: Anthony Basile; T V Dunwiddie
Norepinephrine elicits both excitatory and inhibitory responses from Purkinje cells in the in vitro rat cerebellar slice.
Brain research 1984;296(1):15-25.
1984: T V Dunwiddie; Anthony Basile; M R Palmer
Electrophysiological responses to adenosine analogs in rat hippocampus and cerebellum: evidence for mediation by adenosine receptors of the A1 subtype.
Life sciences 1984;34(1):37-47.