FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Dimitrios Moskofidis

Research Profile

Living Beings

Disorders

Anatomy

Chemicals & Drugs

Procedures

Passive Immunization

Physiology

Cytotoxicity, Immunologic

Co-author Network

Publications

TOP 3
Xiongjie Jin; Wonkyoung Cho; Binnur Eroglu; Dimitrios Moskofidis; Yukihiro Yamaguchi; Nahid F Mivechi
Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis in vivo.
Xiongjie Jin; Dimitrios Moskofidis; Nahid F Mivechi
Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome.
Xiongjie Jin; Binnur Eroglu; Dimitrios Moskofidis; Nahid F Mivechi
Targeted deletion of Hsf1, 2, and 4 genes in mice.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Dimitrios Moskofidis (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Xiongjie Jin; Wonkyoung Cho; Binnur Eroglu; Dimitrios Moskofidis; Yukihiro Yamaguchi; Nahid F Mivechi
Inactivation of heat shock factor Hsf4 induces cellular senescence and suppresses tumorigenesis in vivo.
Molecular cancer research : MCR 2012;10(4):523-34.
2011: Xiongjie Jin; Dimitrios Moskofidis; Nahid F Mivechi
Heat shock transcription factor 1 is a key determinant of HCC development by regulating hepatic steatosis and metabolic syndrome.
Cell metabolism 2011;14(1):91-103.
2011: Xiongjie Jin; Binnur Eroglu; Dimitrios Moskofidis; Nahid F Mivechi
Targeted deletion of Hsf1, 2, and 4 genes in mice.
Methods in molecular biology (Clifton, N.J.) 2011;787():1-20.
2010: Binnur Eroglu; Dimitrios Moskofidis; Nahid F Mivechi
Loss of Hsp110 leads to age-dependent tau hyperphosphorylation and early accumulation of insoluble amyloid beta.
Molecular and cellular biology 2010;30(19):4626-43.
2009: Xiongjie Jin; Dimitrios Moskofidis; Yanzhong Hu; Andrew Phillips; Nahid F Mivechi
Heat shock factor 1 deficiency via its downstream target gene alphaB-crystallin (Hspb5) impairs p53 degradation.
Journal of cellular biochemistry 2009;107(3):504-15.
2008: Minjie Chen; Shuiyun Lan; Rong Ou; Graeme E Price; Hong Jiang; Juan Carlos de la Torre; Dimitrios Moskofidis
Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system.
The Journal of general virology 2008;89(Pt 6):1421-33.
2008: Rong Ou; Menghua Zhang; Lei Huang; Dimitrios Moskofidis
Control of virus-specific CD8+ T-cell exhaustion and immune-mediated pathology by E3 ubiquitin ligase Cbl-b during chronic viral infection.
Journal of virology 2008;82(7):3353-68.
2008: Rong Ou; Menghua Zhang; Lei Huang; Richard A Flavell; Pandelakis Koni; Dimitrios Moskofidis
Regulation of immune response and inflammatory reactions against viral infection by VCAM-1.
Journal of virology 2008;82(6):2952-65.
2007: Jin-Na Min; Lei Huang; Drazen Zimonjic; Dimitrios Moskofidis; Nahid F Mivechi
Selective suppression of lymphomas by functional loss of Hsf1 in a p53-deficient mouse model for spontaneous tumors.
Oncogene 2007;26(35):5086-97.
2007: Lei Huang; Jin-Na Min; Shane Masters; Nahid F Mivechi; Dimitrios Moskofidis
Insights into function and regulation of small heat shock protein 25 (HSPB1) in a mouse model with targeted gene disruption.
Genesis (New York, N.Y. : 2000) 2007;45(8):487-501.
2005: Graeme E Price; Lei Huang; Rong Ou; Menghua Zhang; Dimitrios Moskofidis
Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus.
Journal of virology 2005;79(13):8545-59.
2004: Jin-Na Min; Yan Zhang; Dimitrios Moskofidis; Nahid F Mivechi
Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation.
Genesis (New York, N.Y. : 2000) 2004;40(4):205-17.
2004: Matthew A Gronski; Jonathan M Boulter; Dimitrios Moskofidis; Linh T Nguyen; Kaisa Holmberg; Alisha R Elford; Elissa K Deenick; Hee O Kim; Josef M Penninger; Bernhard Odermatt; Awen Gallimore; Nicholas R J Gascoigne; Pamela S Ohashi
TCR affinity and negative regulation limit autoimmunity.
Nature medicine 2004;10(11):1234-9.
2004: Shenghua Zhou; Rong Ou; Lei Huang; Graeme E Price; Dimitrios Moskofidis
Differential tissue-specific regulation of antiviral CD8+ T-cell immune responses during chronic viral infection.
Journal of virology 2004;78(7):3578-600.
2004: Guanghu Wang; Zhekang Ying; Xiongjie Jin; Naxin Tu; Yan Zhang; Michele Phillips; Dimitrios Moskofidis; Nahid F Mivechi
Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility.
Genesis (New York, N.Y. : 2000) 2004;38(2):66-80.
2003: Guanghu Wang; Jing Zhang; Dimitrios Moskofidis; Nahid F Mivechi
Targeted disruption of the heat shock transcription factor (hsf)-2 gene results in increased embryonic lethality, neuronal defects, and reduced spermatogenesis.
Genesis (New York, N.Y. : 2000) 2003;36(1):48-61.
2002: Yan Zhang; Lei Huang; Jing Zhang; Dimitrios Moskofidis; Nahid F Mivechi
Targeted disruption of hsf1 leads to lack of thermotolerance and defines tissue-specific regulation for stress-inducible Hsp molecular chaperones.
Journal of cellular biochemistry 2002;86(2):376-93.
2002: Shenghua Zhou; Rong Ou; Lei Huang; Dimitrios Moskofidis
Critical role for perforin-, Fas/FasL-, and TNFR1-mediated cytotoxic pathways in down-regulation of antigen-specific T cells during persistent viral infection.
Journal of virology 2002;76(2):829-40.
2001: Lei Huang; Nahid F Mivechi; Dimitrios Moskofidis
Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.
Molecular and cellular biology 2001;21(24):8575-91.
2001: Rong Ou; Shenghua Zhou; Lei Huang; Dimitrios Moskofidis
Critical role for alpha/beta and gamma interferons in persistence of lymphocytic choriomeningitis virus by clonal exhaustion of cytotoxic T cells.
Journal of virology 2001;75(18):8407-23.
2001: Srinagesh V Koushik; Jian Wang; Rhonda Rogers; Dimitrios Moskofidis; Nevin A Lambert; Tony L Creazzo; Simon J Conway
Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(7):1209-11.
2000: Graeme E Price; Rong Ou; H Jiang; Lei Huang; Dimitrios Moskofidis
Viral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia.
The Journal of experimental medicine 2000;191(11):1853-67.
2000: Graeme E Price; A Gaszewska-Mastarlarz; Dimitrios Moskofidis
The role of alpha/beta and gamma interferons in development of immunity to influenza A virus in mice.
Journal of virology 2000;74(9):3996-4003.
1998: Dimitrios Moskofidis; Dimitris Kioussis
Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model.
The Journal of experimental medicine 1998;188(2):223-32.
1998: R Tarazona; Owen Williams; Dimitrios Moskofidis; Lesley A Smyth; Y Tanaka; M Murdjeva; A Wack; Clio Mamalaki; Dimitris Kioussis
Susceptibility and resistance to antigen-induced apoptosis in the thymus of transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5397-403.
1997: Dimitrios Moskofidis; M Moskophidis; J Löhler
Virus-specific IgD in acute viral infection of mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(3):1254-61.
1995: Dimitrios Moskofidis; Rolf M Zinkernagel
Immunobiology of cytotoxic T-cell escape mutants of lymphocytic choriomeningitis virus.
Journal of virology 1995;69(4):2187-93.
1995: Dimitrios Moskofidis; M Battegay; Maries van den Broek; Elisabeth Laine; Urs Hoffmann-Rohrer; Rolf M Zinkernagel
Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus.
The Journal of general virology 1995;76 ( Pt 2)():381-91.
1994: M Battegay; Dimitrios Moskofidis; Amin Rahemtulla; Hans Hengartner; T W Mak; Rolf M Zinkernagel
Enhanced establishment of a virus carrier state in adult CD4+ T-cell-deficient mice.
Journal of virology 1994;68(7):4700-4.
1994: P Corbella; Dimitrios Moskofidis; E Spanopoulou; Clio Mamalaki; Mauro Tolaini; A Itano; D Lans; David Baltimore; Ellen A Robey; Dimitris Kioussis
Functional commitment to helper T cell lineage precedes positive selection and is independent of T cell receptor MHC specificity.
Immunity 1994;1(4):269-76.
1994: Dimitrios Moskofidis; F Lechner; Hans Hengartner; Rolf M Zinkernagel
MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(10):4976-83.
1994: Dimitrios Moskofidis; M Battegay; M A Bruendler; Elisabeth Laine; I Gresser; Rolf M Zinkernagel
Resistance of lymphocytic choriomeningitis virus to alpha/beta interferon and to gamma interferon.
Journal of virology 1994;68(3):1951-5.
1993: Dimitrios Moskofidis; Elisabeth Laine; Rolf M Zinkernagel
Peripheral clonal deletion of antiviral memory CD8+ T cells.
European journal of immunology 1993;23(12):3306-11.
1993: M Battegay; Dimitrios Moskofidis; H Waldner; M A Bründler; W P Fung-Leung; T W Mak; Hans Hengartner; Rolf M Zinkernagel
Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(10):5408-15.
1993: Rolf M Zinkernagel; Dimitrios Moskofidis; TM Kündig; Stephan Oehen; Hanspeter Pircher; Hans Hengartner
Effector T-cell induction and T-cell memory versus peripheral deletion of T cells.
Immunological reviews 1993;133():199-223.
1993: Dimitrios Moskofidis; F Lechner; Hanspeter Pircher; Rolf M Zinkernagel
Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells.
Nature 1993;362(6422):758-61.
1992: Alana Althage; B Odermatt; Dimitrios Moskofidis; TM Kündig; Urs Hoffmann-Rohrer; Hans Hengartner; Rolf M Zinkernagel
Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation.
European journal of immunology 1992;22(7):1803-12.
1992: Dimitrios Moskofidis; Hanspeter Pircher; I Ciernik; B Odermatt; Hans Hengartner; Rolf M Zinkernagel
Suppression of virus-specific antibody production by CD8+ class I-restricted antiviral cytotoxic T cells in vivo.
Journal of virology 1992;66(6):3661-8.
1991: T Aebischer; Dimitrios Moskofidis; Urs Hoffmann-Rohrer; Rolf M Zinkernagel; Hans Hengartner
In vitro selection of lymphocytic choriomeningitis virus escape mutants by cytotoxic T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11047-51.
1991: Hanspeter Pircher; Urs Hoffmann-Rohrer; Dimitrios Moskofidis; Rolf M Zinkernagel; Hans Hengartner
Lower receptor avidity required for thymic clonal deletion than for effector T-cell function.
Nature 1991;351(6326):482-5.
1991: Dimitrios Moskofidis; K Frei; Jürgen Löhler; A Fontana; Rolf M Zinkernagel
Production of random classes of immunoglobulins in brain tissue during persistent viral infection paralleled by secretion of interleukin-6 (IL-6) but not IL-4, IL-5, and gamma interferon.
Journal of virology 1991;65(3):1364-9.
1990: Hanspeter Pircher; Dimitrios Moskofidis; Urs Hoffmann-Rohrer; K Bürki; Hans Hengartner; Rolf M Zinkernagel
Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo.
Nature 1990;346(6285):629-33.
1990: Dimitrios Moskofidis; L Fang; J Gossmann; R Drjupin; Jürgen Löhler; Michael Bruns; F Lehmann-Grube
Virus-specific delayed-type hypersensitivity (DTH). Cells mediating lymphocytic choriomeningitis virus-specific DTH reaction in mice.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(5):1926-34.
1989: Dimitrios Moskofidis; L Fang; J Gossmann; F Lehmann-Grube
Mechanism of recovery from acute virus infection. IX. Clearance of lymphocytic choriomeningitis (LCM) virus from the feet of mice undergoing LCM virus-specific delayed-type hypersensitivity reaction.
The Journal of general virology 1989;70 ( Pt 12)():3305-16.
1989: Dimitrios Moskofidis; F Lehmann-Grube
Virus-induced delayed-type hypersensitivity reaction is sequentially mediated by CD8+ and CD4+ T lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(9):3291-5.
1989: A Gessner; Dimitrios Moskofidis; F Lehmann-Grube
Enumeration of single IFN-gamma-producing cells in mice during viral and bacterial infection.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(4):1293-8.
1989: F Lehmann-Grube; Dimitrios Moskofidis
Lymphocytic choriomeningitis virus-specific delayed-type hypersensitivity reaction in mice.
Advances in experimental medicine and biology 1989;257():91-107.
1988: F Lehmann-Grube; Dimitrios Moskofidis; Jürgen Löhler
Recovery from acute virus infection. Role of cytotoxic T lymphocytes in the elimination of lymphocytic choriomeningitis virus from spleens of mice.
Annals of the New York Academy of Sciences 1988;532():238-56.
1987: Dimitrios Moskofidis; U Assmann-Wischer; M M Simon; F Lehmann-Grube
The immune response of the mouse to lymphocytic choriomeningitis virus. V. High numbers of cytolytic T lymphocytes are generated in the spleen during acute infection.
European journal of immunology 1987;17(7):937-42.
1987: Dimitrios Moskofidis; S P Cobbold; H Waldmann; F Lehmann-Grube
Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response.
Journal of virology 1987;61(6):1867-74.
1987: F Lehmann-Grube; I Krenz; T Krahnert; R Schwachenwald; Dimitrios Moskofidis; Jürgen Löhler; C J Villeda Posada
Mechanism of recovery from acute virus infection. IV. Questionable role of mononuclear phagocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(7):2282-9.
1987: Dimitrios Moskofidis; Jürgen Löhler; F Lehmann-Grube
Antiviral antibody-producing cells in parenchymatous organs during persistent virus infection.
The Journal of experimental medicine 1987;165(3):705-19.
1986: Dimitrios Moskofidis; Jürgen Löhler; F Lehmann-Grube
Antiviral antibody production in parenchymatous organs of lymphocytic choriomeningitis virus carrier mice. Enumeration of antibody-producing cells and immunohistochemical investigation of mononuclear cell infiltrates.
Medical microbiology and immunology 1986;175(2-3):113-6.
1986: U Assmann-Wischer; Dimitrios Moskofidis; M M Simon; F Lehmann-Grube
Numbers of cytolytic T lymphocytes (CTL) and CTL precursor cells in spleens of mice acutely infected with lymphocytic choriomeningitis virus.
Medical microbiology and immunology 1986;175(2-3):141-3.
1986: F Lehmann-Grube; U Assmann-Wischer; R Schwachenwald; I Krenz; T Krahnert; Dimitrios Moskofidis
Questionable role of mononuclear phagocytes in the elimination of lymphocytic choriomeningitis virus from spleens of acutely infected mice.
Medical microbiology and immunology 1986;175(2-3):145-8.
1985: F Lehmann-Grube; U Assmann; C Löliger; Dimitrios Moskofidis; Jürgen Löhler
Mechanism of recovery from acute virus infection. I. Role of T lymphocytes in the clearance of lymphocytic choriomeningitis virus from spleens of mice.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(1):608-15.
1984: Dimitrios Moskofidis; F Lehmann-Grube
The immune response of the mouse to lymphocytic choriomeningitis virus. IV. Enumeration of antibody-producing cells in spleens during acute and persistent infection.
Journal of immunology (Baltimore, Md. : 1950) 1984;133(6):3366-70.
1983: Dimitrios Moskofidis; F Lehmann-Grube
The immune response of the mouse to lymphocytic choriomeningitis virus. III. Differences of numbers of cytotoxic T lymphocytes in spleens of mice of different strains.
Cellular immunology 1983;77(2):279-89.